## Sat Jan 4 12:18:39 2025 ## emapper-2.1.12 ## /data/home/zhuyingjie/miniforge3/envs/eggnog/bin/emapper.py -i /data/home/zhuyingjie/01_Project/01_metagenome/mangrove/mmseqs_cluster/PRJNA437562/SRR6820483/SRR6820483_p_cluster_rep_seq.fasta --output PRJNA437562_SRR6820483 --data_dir /data/software/eggnog_database -m diamond --sensmode fast --output_dir /data/home/zhuyingjie/01_Project/01_metagenome/mangrove/annotation --temp_dir /data/software/eggnog_database/temp --excel --dbmem --cpu 24 ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs k59_206704_3 1236542.BALM01000032_gene2206 3.28e-25 101.0 2DNV9@1|root,32ZB3@2|Bacteria,1MZGP@1224|Proteobacteria,1TB15@1236|Gammaproteobacteria,2QCDU@267890|Shewanellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_158114_2 1408418.JNJH01000002_gene2754 4.46e-14 79.3 COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,2TT4Q@28211|Alphaproteobacteria,2JV16@204441|Rhodospirillales 204441|Rhodospirillales L Uracil DNA glycosylase superfamily - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_145954_2 1234888.K0A2J2_9VIRU 5.71e-79 262.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_194558_1 428125.CLOLEP_01375 2.52e-64 224.0 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia,3WNBH@541000|Ruminococcaceae 186801|Clostridia S DNA polymerase type-B family - - - - - - - - - - - - - k59_85226_3 1197951.I6S2A3_9CAUD 2.26e-29 117.0 4QAIV@10239|Viruses,4QYFZ@35237|dsDNA viruses no RNA stage,4QQUY@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_170260_1 490913.B0FLN5_9CAUD 5.54e-46 166.0 4QGGR@10239|Viruses,4QZHR@35237|dsDNA viruses no RNA stage,4QUGZ@28883|Caudovirales,4QNY3@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_170260_2 1477404.A0A023NGT6_9CAUD 1.75e-30 128.0 4QEQT@10239|Viruses,4QYJH@35237|dsDNA viruses no RNA stage,4QQ1B@28883|Caudovirales,4QNPW@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_267331_6 1121033.AUCF01000017_gene3816 9.62e-39 135.0 COG0741@1|root,COG0741@2|Bacteria,1N0U8@1224|Proteobacteria,2UICK@28211|Alphaproteobacteria,2JTZJ@204441|Rhodospirillales 204441|Rhodospirillales M lytic transglycosylase activity - - - - - - - - - - - - - k59_267331_11 1122201.AUAZ01000017_gene2962 4.88e-14 83.6 COG4675@1|root,COG4675@2|Bacteria 2|Bacteria M tail collar domain protein - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - Collar,Phage_fiber_2 k59_255203_1 97139.C824_00718 1.51e-67 228.0 COG5525@1|root,COG5525@2|Bacteria,1TQBY@1239|Firmicutes,248DP@186801|Clostridia,36GN9@31979|Clostridiaceae 186801|Clostridia S Phage terminase large subunit (GpA) - - - - - - - - - - - - Terminase_GpA k59_255203_3 198467.NP92_02815 9.66e-167 489.0 COG5511@1|root,COG5511@2|Bacteria,1TQ8B@1239|Firmicutes,4HCQE@91061|Bacilli 91061|Bacilli S Portal protein - - - - - - - - - - - - Phage_portal_2 k59_255203_4 1265502.KB905934_gene3148 4.66e-26 117.0 COG0616@1|root,COG0616@2|Bacteria,1QGPW@1224|Proteobacteria,2VJ0N@28216|Betaproteobacteria,4AB1E@80864|Comamonadaceae 28216|Betaproteobacteria OU PFAM peptidase S49 - - - - - - - - - - - - Peptidase_S49 k59_255203_5 1041159.AZUW01000001_gene3268 6.54e-59 187.0 2AD4I@1|root,300N2@2|Bacteria,1PR6C@1224|Proteobacteria,2V3HE@28211|Alphaproteobacteria,4BKMT@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_255203_6 1121918.ARWE01000001_gene767 1.39e-106 320.0 COG4397@1|root,COG4397@2|Bacteria,1MWX8@1224|Proteobacteria,42QUQ@68525|delta/epsilon subdivisions,2WN4N@28221|Deltaproteobacteria,43VF0@69541|Desulfuromonadales 28221|Deltaproteobacteria S Mu-like prophage major head subunit gpT - - - - - - - - - - - - Mu-like_gpT k59_255203_14 1492922.GY26_15975 1.22e-35 149.0 COG1196@1|root,COG1511@1|root,COG1196@2|Bacteria,COG1511@2|Bacteria 2|Bacteria Q domain protein - - - ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - DUF349 k59_255203_16 1121861.KB899916_gene1627 8.7e-155 468.0 COG4733@1|root,COG4733@2|Bacteria,1R7KR@1224|Proteobacteria,2TWI9@28211|Alphaproteobacteria,2JUCZ@204441|Rhodospirillales 204441|Rhodospirillales S Putative phage tail protein - - - - - - - - - - - - Phage-tail_3 k59_255203_18 1307436.PBF_16639 4.31e-67 234.0 29SKA@1|root,30DRK@2|Bacteria,1UBKX@1239|Firmicutes,4IN15@91061|Bacilli,1ZMHH@1386|Bacillus 91061|Bacilli S Right handed beta helix region - - - - - - - - - - - - Beta_helix k59_255203_21 255131.Q6JIG5_9CAUD 1.19e-52 171.0 4QC6A@10239|Viruses,4QWAW@35237|dsDNA viruses no RNA stage,4QPWF@28883|Caudovirales,4QMHG@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_255203_22 765913.ThidrDRAFT_2489 1.37e-52 184.0 COG0582@1|root,COG0582@2|Bacteria,1QB64@1224|Proteobacteria,1S8Y0@1236|Gammaproteobacteria,1X12F@135613|Chromatiales 135613|Chromatiales L Belongs to the 'phage' integrase family - - - - - - - - - - - - - k59_255203_23 634500.EbC_32190 2.1e-94 284.0 COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,1T9QJ@1236|Gammaproteobacteria,3X7X3@551|Erwinia 1236|Gammaproteobacteria H C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_377741_4 758.BBIX01000008_gene920 1.52e-40 154.0 2CI0W@1|root,2Z81W@2|Bacteria,1R9FZ@1224|Proteobacteria,1S0NA@1236|Gammaproteobacteria,1Y9SV@135625|Pasteurellales 135625|Pasteurellales S Phage X family - - - - - - - - - - - - Phage_CRI,Phage_X k59_377741_10 1122194.AUHU01000013_gene665 5.91e-62 205.0 COG4128@1|root,COG4128@2|Bacteria,1REHG@1224|Proteobacteria,1S491@1236|Gammaproteobacteria,46BRE@72275|Alteromonadaceae 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_256101_4 1410666.JHXG01000008_gene681 2.87e-11 60.8 COG4734@1|root,COG4734@2|Bacteria 2|Bacteria S Antirestriction protein (ArdA) ardA - - - - - - - - - - - ArdA k59_171123_1 1123320.KB889698_gene9323 9.75e-07 55.5 COG2133@1|root,COG3055@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3055@2|Bacteria,COG3291@2|Bacteria 2|Bacteria S metallopeptidase activity - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - Calx-beta,GSDH,Laminin_G_3,Malectin,PKD k59_134563_2 1173264.KI913949_gene405 2.85e-19 87.8 COG0451@1|root,COG0451@2|Bacteria,1G02N@1117|Cyanobacteria,1H7SE@1150|Oscillatoriales 1117|Cyanobacteria GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction fcl - 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R05692 RC01014 ko00000,ko00001,ko01000 - - - Epimerase k59_317049_1 999541.bgla_1g23430 1.03e-17 96.3 COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,1MUG9@1224|Proteobacteria,2VIKN@28216|Betaproteobacteria,1K18Q@119060|Burkholderiaceae 28216|Betaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_37501_2 1121930.AQXG01000006_gene890 1.31e-19 99.4 COG3941@1|root,COG3941@2|Bacteria 2|Bacteria O tape measure - - - - - - - - - - - - Tape_meas_lam_C k59_207801_2 86106.I862_04250 8.59e-24 97.4 COG0791@1|root,COG0791@2|Bacteria,1Q7G2@1224|Proteobacteria,2VDMF@28211|Alphaproteobacteria,47GHF@766|Rickettsiales 766|Rickettsiales M NLP P60 protein - - - - - - - - - - - - - k59_207801_3 311402.Avi_1351 9.79e-14 72.4 COG5449@1|root,COG5449@2|Bacteria,1MXK2@1224|Proteobacteria,2TTWS@28211|Alphaproteobacteria,4BBHK@82115|Rhizobiaceae 28211|Alphaproteobacteria S Phage conserved hypothetical protein BR0599 - - - - - - - - - - - - DUF2163,Phage_BR0599 k59_98274_3 202954.BBNK01000034_gene3794 8.76e-45 149.0 2A3Q7@1|root,30S7S@2|Bacteria,1NP2K@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_365354_1 1484158.PSNIH1_19155 4.28e-38 140.0 28J67@1|root,2Z91Y@2|Bacteria,1R7RG@1224|Proteobacteria,1RZB8@1236|Gammaproteobacteria,3W0AP@53335|Pantoea 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_292732_1 1541960.KQ78_01196 1.43e-10 70.5 28MKK@1|root,2ZAWR@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_377851_3 666509.RCA23_c02160 5.26e-20 90.9 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 k59_12965_4 401053.AciPR4_3094 4.47e-20 93.2 COG0270@1|root,COG0270@2|Bacteria,3Y5V5@57723|Acidobacteria,2JNSG@204432|Acidobacteriia 204432|Acidobacteriia L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_50756_2 1166948.JPZL01000002_gene1836 1.86e-21 87.4 2EMXC@1|root,33FJM@2|Bacteria,1NFNP@1224|Proteobacteria,1SIUQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_160285_1 1788445.A0A190WHA3_9CIRC 1.02e-55 187.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_111460_1 1396858.Q666_00425 4.96e-08 60.5 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,465DD@72275|Alteromonadaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_99289_4 795666.MW7_1046 1.6e-14 79.7 COG4733@1|root,COG4733@2|Bacteria,1MXB4@1224|Proteobacteria,2VJS7@28216|Betaproteobacteria 28216|Betaproteobacteria M Putative phage tail protein - - - - - - - - - - - - Phage-tail_3 k59_13574_3 1385658.U5KPZ6_9VIRU 8.51e-203 582.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_13574_7 1609634.A0A0C5AFT2_9VIRU 1.09e-19 92.8 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_306017_1 1676988.A0A0H4FV52_9CIRC 4.55e-55 191.0 4QGVY@10239|Viruses,4QUKN@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_135665_1 1385658.U5KNR1_9VIRU 1.58e-27 111.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_135665_3 1609634.A0A0C5AFV4_9VIRU 9.34e-09 56.2 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_330440_2 1121935.AQXX01000096_gene2564 2.35e-10 61.6 COG1396@1|root,COG1396@2|Bacteria,1N6TH@1224|Proteobacteria,1SFCK@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Helix-turn-helix domain - - - - - - - - - - - - HTH_19,HTH_3,HTH_31 k59_50767_1 105154.Q9MBU3_9VIRU 1.06e-15 79.0 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_50767_2 1609634.A0A0C5AFV4_9VIRU 1.94e-101 312.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_13576_1 105154.Q9MBU6_9VIRU 3.26e-75 247.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_2132_1 1150626.PHAMO_180128 5.95e-13 77.4 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,2TVGJ@28211|Alphaproteobacteria,2JPR0@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_330446_1 1609634.A0A0C5AFV4_9VIRU 6.49e-54 188.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_172263_1 1618248.A0A0C5IB82_9CIRC 8.43e-100 302.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_172263_2 1692242.A0A0K1RKZ2_9CIRC 0.000674 48.9 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_318356_1 1500301.JQMF01000006_gene1773 5.49e-08 59.3 COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria,2U1JR@28211|Alphaproteobacteria,4BC0X@82115|Rhizobiaceae 28211|Alphaproteobacteria K DNA-directed RNA polymerase N-terminal - - - - - - - - - - - - RNA_pol,RPOL_N k59_99300_2 670292.JH26_14425 1.12e-67 210.0 2DIG9@1|root,3036R@2|Bacteria,1RBPA@1224|Proteobacteria,2U6EP@28211|Alphaproteobacteria,1JV25@119045|Methylobacteriaceae 28211|Alphaproteobacteria L YqaJ-like viral recombinase domain - - - - - - - - - - - - YqaJ k59_135666_2 1692244.A0A0K1RLR5_9CIRC 2.17e-40 147.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_342396_6 1589751.A0A0C5AEN1_9CAUD 2.39e-11 72.8 4QBNM@10239|Viruses,4QPUI@28883|Caudovirales,4QKV6@10699|Siphoviridae 10699|Siphoviridae S Clp protease - - - - - - - - - - - - - k59_342396_8 1437882.AZRU01000081_gene6687 1.25e-38 147.0 28H75@1|root,2Z7JG@2|Bacteria,1MU3Y@1224|Proteobacteria,1S198@1236|Gammaproteobacteria,1YI2X@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Phage major capsid protein E - - - - - - - - - - - - Phage_cap_E k59_209918_2 1986029.Q9MBM3_9VIRU 4.68e-67 219.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_331345_2 1618259.A0A0C5I2B5_9CIRC 3.54e-104 313.0 4QE84@10239|Viruses,4QUKR@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_184172_1 352165.HMPREF7215_2560 1.47e-44 167.0 COG0749@1|root,COG0749@2|Bacteria 2|Bacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_pol_A,RNase_H_2 k59_184172_3 935261.JAGL01000009_gene1171 1.72e-51 175.0 COG0258@1|root,COG0258@2|Bacteria,1MYSI@1224|Proteobacteria,2U60N@28211|Alphaproteobacteria 28211|Alphaproteobacteria L 5'-3' exonuclease, N-terminal resolvase-like domain - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc_N k59_184172_4 563192.HMPREF0179_02930 6.12e-19 80.1 2EI4V@1|root,33BW7@2|Bacteria,1NN3Z@1224|Proteobacteria,432C4@68525|delta/epsilon subdivisions,2WXM5@28221|Deltaproteobacteria,2MFUS@213115|Desulfovibrionales 1224|Proteobacteria S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_319174_3 1618256.A0A0C5IM93_9CIRC 3.15e-44 160.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_197366_1 760117.JN27_02580 2.71e-08 59.7 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,475VU@75682|Oxalobacteraceae 28216|Betaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GAF_2,GGDEF,PAS_3,PAS_9,Response_reg k59_124773_1 428125.CLOLEP_01412 6.66e-45 163.0 28JK5@1|root,2Z9D1@2|Bacteria,1UJZJ@1239|Firmicutes,24D64@186801|Clostridia,3WMZ3@541000|Ruminococcaceae 186801|Clostridia S Caudovirus prohead serine protease - - - - - - - - - - - - Peptidase_S78 k59_342978_1 1449335.JQLG01000003_gene5 4.74e-20 95.5 COG0270@1|root,COG0863@1|root,COG1092@1|root,COG0270@2|Bacteria,COG0863@2|Bacteria,COG1092@2|Bacteria,1TSNX@1239|Firmicutes,4HFAI@91061|Bacilli,27GXX@186828|Carnobacteriaceae 91061|Bacilli L C-5 cytosine-specific DNA methylase dcm GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0008168,GO:0009307,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0032776,GO:0034641,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044728,GO:0046483,GO:0050896,GO:0071704,GO:0090304,GO:0099046,GO:1901360 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase,N6_N4_Mtase k59_342978_3 1172190.M947_08555 3.29e-08 58.2 COG4627@1|root,COG4627@2|Bacteria,1R035@1224|Proteobacteria,42Q15@68525|delta/epsilon subdivisions,2YRTE@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S overlaps another CDS with the same product name - - - - - - - - - - - - Methyltransf_11 k59_14215_2 411460.RUMTOR_01348 2.55e-172 496.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_14215_3 691965.D4P7D6_9CAUD 4.17e-219 635.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_14215_4 411460.RUMTOR_01344 1.01e-37 129.0 2E2Y0@1|root,32XYV@2|Bacteria,1VD9S@1239|Firmicutes,24PK0@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_14215_5 691965.D4P7D8_9CAUD 4.27e-39 132.0 4QBBW@10239|Viruses,4QXCP@35237|dsDNA viruses no RNA stage,4QQ3N@28883|Caudovirales,4QN1X@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_14215_6 742733.HMPREF9469_05026 1.33e-85 260.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia,221N8@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_14215_7 428125.CLOLEP_01417 4.71e-49 164.0 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia,3WMXK@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_14215_10 691965.D4P7E5_9CAUD 6.29e-38 131.0 4QEVD@10239|Viruses,4QW84@35237|dsDNA viruses no RNA stage,4QQSX@28883|Caudovirales,4QMU4@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_27407_2 1211640.K4JUD3_9CAUD 3.32e-17 82.4 4QB08@10239|Viruses,4QY8E@35237|dsDNA viruses no RNA stage,4QRIV@28883|Caudovirales,4QM5X@10699|Siphoviridae 10699|Siphoviridae S exonuclease activity - - - - - - - - - - - - - k59_331525_1 324057.Pjdr2_5076 1.56e-06 51.2 COG1554@1|root,COG1621@1|root,COG1653@1|root,COG2374@1|root,COG3250@1|root,COG3828@1|root,COG4733@1|root,COG1554@2|Bacteria,COG1621@2|Bacteria,COG1653@2|Bacteria,COG2374@2|Bacteria,COG3250@2|Bacteria,COG3828@2|Bacteria,COG4733@2|Bacteria,1TQ2S@1239|Firmicutes,4HF4P@91061|Bacilli 91061|Bacilli G Glycosyl hydrolase family 65, N-terminal domain - - - - - - - - - - - - Glyco_hyd_65N_2 k59_3303_1 742740.HMPREF9474_02271 4.73e-149 434.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia,221RR@1506553|Lachnoclostridium 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_222148_1 1054213.HMPREF9946_02152 5.68e-12 74.3 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TTEX@28211|Alphaproteobacteria,2JVUB@204441|Rhodospirillales 204441|Rhodospirillales S Terminase - - - - - - - - - - - - Terminase_1 k59_124919_1 488538.SAR116_0377 3.82e-128 383.0 COG4373@1|root,COG4373@2|Bacteria 2|Bacteria - - gp17a - - ko:K06909 - - - - ko00000 - - - Terminase_6,Terminase_6C k59_88976_2 181604.Q8W6D1_9VIRU 5.37e-07 51.6 4QGF7@10239|Viruses,4QUKH@29258|ssDNA viruses,4QP4F@10860|Inoviridae 10860|Inoviridae S Protein of unknown function (DUF2523) - - - - - - - - - - - - - k59_52467_3 1121441.AUCX01000014_gene514 1.04e-70 231.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,43BCR@68525|delta/epsilon subdivisions,2X6RN@28221|Deltaproteobacteria,2MA58@213115|Desulfovibrionales 28221|Deltaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_52467_4 1121921.KB898707_gene975 2.47e-82 261.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,1RY0J@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_4111_3 1048339.KB913029_gene3504 1.11e-67 228.0 COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4ERCB@85013|Frankiales 201174|Actinobacteria P Ammonium Transporter amtB - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k59_65029_1 2002.JOEQ01000057_gene7009 2.29e-34 130.0 2AW6S@1|root,31N1T@2|Bacteria,2INYW@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_295676_2 1172188.KB911820_gene2858 8.35e-26 116.0 COG0739@1|root,COG0741@1|root,COG0739@2|Bacteria,COG0741@2|Bacteria,2IGMV@201174|Actinobacteria 201174|Actinobacteria M Transglycosylase SLT domain - - - - - - - - - - - - PG_binding_1,SLT,T7SS_ESX_EspC k59_295676_8 1121370.AQUY01000001_gene998 2.14e-20 89.4 COG4570@1|root,COG4570@2|Bacteria,2GV9V@201174|Actinobacteria,22PE8@1653|Corynebacteriaceae 201174|Actinobacteria L Endodeoxyribonuclease RusA - - - - - - - - - - - - RusA k59_295676_10 1034101.G1D1F5_9CAUD 1.35e-67 221.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_211041_1 1234888.K0A2J2_9VIRU 2.88e-37 141.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_234798_1 888743.HMPREF9141_0984 0.000468 49.3 2EVUA@1|root,33P81@2|Bacteria,4P82D@976|Bacteroidetes,2FV68@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_307924_1 1122962.AULH01000009_gene3851 8.82e-48 179.0 28IJ1@1|root,2Z8K0@2|Bacteria,1R5PC@1224|Proteobacteria,2U0RA@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_40128_1 1238450.VIBNISOn1_1190023 4.22e-16 82.4 2F6W9@1|root,33ZCB@2|Bacteria,1NZ0D@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_247748_1 1986029.Q9MBM3_9VIRU 4.13e-70 227.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_321168_1 765910.MARPU_05585 9.44e-15 77.8 COG1074@1|root,COG1074@2|Bacteria,1QUUZ@1224|Proteobacteria,1T21W@1236|Gammaproteobacteria 1236|Gammaproteobacteria L PDDEXK-like domain of unknown function (DUF3799) - - - - - - - - - - - - DUF3799 k59_212215_2 665956.HMPREF1032_00640 1.03e-45 162.0 2A0KC@1|root,2ZGJK@2|Bacteria,1V2JS@1239|Firmicutes,24H6R@186801|Clostridia,3WNJK@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_321339_1 1323663.AROI01000010_gene3261 2.06e-06 54.7 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RMJ1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase k59_199488_2 69279.BG36_20805 5.24e-24 108.0 2AA25@1|root,30ZAV@2|Bacteria,1PM8F@1224|Proteobacteria,2UZVR@28211|Alphaproteobacteria,43QIT@69277|Phyllobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_138657_1 1234888.K0A2J2_9VIRU 2.69e-94 294.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_286038_2 631362.Thi970DRAFT_03408 3.42e-16 77.0 COG4627@1|root,COG4627@2|Bacteria,1N2HA@1224|Proteobacteria,1SJB1@1236|Gammaproteobacteria 1236|Gammaproteobacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Methyltransf_11 k59_16240_1 1692244.A0A0K1RLR5_9CIRC 2.3e-53 176.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_369213_1 1321814.HMPREF9089_00915 1.94e-16 81.6 COG0827@1|root,COG0827@2|Bacteria,1UZYQ@1239|Firmicutes,24E9W@186801|Clostridia 186801|Clostridia L DNA restriction-modification system - - - - - - - - - - - - - k59_369213_4 1282887.AUJG01000002_gene983 2.04e-29 132.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia 186801|Clostridia L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_321352_2 1157637.KB892115_gene4570 3.07e-30 129.0 COG5280@1|root,COG5283@1|root,COG5280@2|Bacteria,COG5283@2|Bacteria,2I3FN@201174|Actinobacteria 201174|Actinobacteria M NLP P60 protein - - - - - - - - - - - - PhageMin_Tail k59_248839_1 1123248.KB893322_gene688 9.93e-25 108.0 COG0582@1|root,COG0582@2|Bacteria,4NDZJ@976|Bacteroidetes,1ISHB@117747|Sphingobacteriia 976|Bacteroidetes L Phage integrase SAM-like domain - - - - - - - - - - - - Arm-DNA-bind_5,Phage_int_SAM_5,Phage_integrase k59_54460_2 753085.F4YCV3_9CAUD 7.27e-76 250.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_225136_1 665950.HMPREF1025_02725 1.35e-11 68.2 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,27RPP@186928|unclassified Lachnospiraceae 186801|Clostridia L DNA polymerase family A - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_273261_1 742918.D4N3P2_9CIRC 1.25e-11 68.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_236533_1 571166.KI421509_gene1201 6.43e-10 67.4 COG3598@1|root,COG3598@2|Bacteria,1R8YZ@1224|Proteobacteria,2U4ZD@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction - - - - - - - - - - - - DUF3987,PriCT_2,Prim-Pol,RepB_primase k59_260633_1 742733.HMPREF9469_05039 2.71e-38 147.0 28JED@1|root,2Z98K@2|Bacteria,1TW1U@1239|Firmicutes,24CFD@186801|Clostridia,2226E@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - GerE k59_260633_2 665956.HMPREF1032_00664 8.33e-68 212.0 29YRZ@1|root,30KMY@2|Bacteria,1V4Y4@1239|Firmicutes,24HPY@186801|Clostridia,3WNNS@541000|Ruminococcaceae 186801|Clostridia S Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_260633_4 742733.HMPREF9469_05062 2.16e-159 462.0 COG0553@1|root,COG0553@2|Bacteria,1TS9W@1239|Firmicutes,24CGX@186801|Clostridia,222GT@1506553|Lachnoclostridium 186801|Clostridia KL Helicase conserved C-terminal domain - - - - - - - - - - - - - k59_127760_2 1379709.S5TMV0_9CIRC 4.29e-72 225.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_151860_1 67267.JNXT01000054_gene2973 1.61e-29 114.0 2EGA5@1|root,33A1Y@2|Bacteria,2GSDD@201174|Actinobacteria 201174|Actinobacteria S HNH endonuclease - - - - - - - - - - - - HNH_3 k59_213255_1 1609634.A0A0C5AFV4_9VIRU 1.09e-203 585.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_213255_3 1609634.A0A0C5AFT2_9VIRU 2.05e-98 298.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_358057_1 326424.FRAAL2754 1.62e-41 151.0 28HEE@1|root,2Z7QU@2|Bacteria,2I1I5@201174|Actinobacteria 201174|Actinobacteria S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_115166_1 145579.REP_BPPHM 3.37e-94 287.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_17161_1 744980.TRICHSKD4_2401 5.04e-31 122.0 COG0863@1|root,COG0863@2|Bacteria,1MY4G@1224|Proteobacteria,2U1X0@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_346336_2 691965.D4P7D9_9CAUD 3.04e-76 236.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_128633_1 1313265.JNIE01000002_gene1000 3.29e-29 124.0 COG0305@1|root,COG0305@2|Bacteria,2G3QP@200783|Aquificae 200783|Aquificae L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_226094_2 1007096.BAGW01000031_gene130 0.000102 48.9 COG4220@1|root,COG4220@2|Bacteria,1VGX7@1239|Firmicutes,24S8B@186801|Clostridia,2N7VZ@216572|Oscillospiraceae 186801|Clostridia L Psort location Cytoplasmic, score - - - - - - - - - - - - - k59_164893_3 1499967.BAYZ01000154_gene1521 1.9e-23 102.0 COG3409@1|root,COG3772@1|root,COG3409@2|Bacteria,COG3772@2|Bacteria 2|Bacteria S cytolysis by virus of host cell - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Amidase_2,CW_binding_1,PG_binding_1,Phage_lysozyme k59_382959_24 926550.CLDAP_29840 3.05e-29 132.0 COG3023@1|root,COG4423@1|root,COG3023@2|Bacteria,COG4423@2|Bacteria 2|Bacteria S positive regulation of growth - - - ko:K19687 - - - - ko00000,ko02048 - - - Amidase_2,PG_binding_1,PSK_trans_fac k59_177528_4 1121459.AQXE01000021_gene67 1.62e-12 65.9 2DMPB@1|root,32SV8@2|Bacteria,1NHUE@1224|Proteobacteria,430VU@68525|delta/epsilon subdivisions,2WW0U@28221|Deltaproteobacteria,2MCJ3@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_226351_1 1414742.V5R8Z5_9CAUD 4.85e-19 95.5 4QBMM@10239|Viruses,4QUYD@35237|dsDNA viruses no RNA stage,4QPIA@28883|Caudovirales,4QMA3@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_371181_1 1168547.L7P648_9CIRC 1.97e-19 92.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_55570_1 247490.KSU1_C1049 2.21e-07 57.8 COG1196@1|root,COG1196@2|Bacteria 2|Bacteria D nuclear chromosome segregation - - - - - - - - - - - - - k59_141401_1 1385658.U5KPZ6_9VIRU 8.28e-36 134.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_80705_1 553217.ENHAE0001_1429 1.16e-161 462.0 COG5527@1|root,COG5527@2|Bacteria,1PR7P@1224|Proteobacteria,1TB4K@1236|Gammaproteobacteria,3NR9Q@468|Moraxellaceae 1236|Gammaproteobacteria L Initiator Replication protein - - - - - - - - - - - - Rep_3 k59_80705_3 1002339.HMPREF9373_2624 7.25e-147 441.0 COG0507@1|root,COG0507@2|Bacteria,1MUTR@1224|Proteobacteria,1RQS3@1236|Gammaproteobacteria,3NJSK@468|Moraxellaceae 1236|Gammaproteobacteria L MobA/MobL family - - - - - - - - - - - - MobA_MobL k59_262457_1 1380394.JADL01000007_gene4591 1.04e-60 202.0 COG0451@1|root,COG0451@2|Bacteria,1RKFJ@1224|Proteobacteria,2UAT9@28211|Alphaproteobacteria 28211|Alphaproteobacteria GM 3-beta hydroxysteroid dehydrogenase/isomerase family - - - - - - - - - - - - Epimerase k59_262457_2 479434.Sthe_2756 7.01e-07 52.8 COG0399@1|root,COG0399@2|Bacteria,2G7XI@200795|Chloroflexi 200795|Chloroflexi E DegT/DnrJ/EryC1/StrS aminotransferase family - - - - - - - - - - - - DegT_DnrJ_EryC1 k59_18636_5 202954.BBNK01000034_gene3794 7.18e-44 146.0 2A3Q7@1|root,30S7S@2|Bacteria,1NP2K@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_129700_1 111780.Sta7437_2298 2.98e-10 66.2 COG1216@1|root,COG1216@2|Bacteria,1G2VA@1117|Cyanobacteria,3VI9D@52604|Pleurocapsales 1117|Cyanobacteria S Glycosyltransferase like family 2 - - - - - - - - - - - - Glyco_tranf_2_2,Glycos_transf_2 k59_238378_1 658655.HMPREF0988_00774 1.65e-09 64.3 COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,24JDA@186801|Clostridia,27NGD@186928|unclassified Lachnospiraceae 186801|Clostridia M Transglycosylase SLT domain yjbJ - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT k59_80849_1 1120792.JAFV01000001_gene967 1.93e-08 59.7 28H5T@1|root,2Z7IB@2|Bacteria,1N7V9@1224|Proteobacteria,2TTZQ@28211|Alphaproteobacteria,3712F@31993|Methylocystaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_372012_1 395961.Cyan7425_4210 6.26e-28 110.0 COG1442@1|root,COG1442@2|Bacteria,1G3Z0@1117|Cyanobacteria,3KKHS@43988|Cyanothece 1117|Cyanobacteria M PFAM glycosyl transferase family 8 - - - - - - - - - - - - - k59_202322_1 522373.Smlt1886 8.13e-45 168.0 COG3378@1|root,COG3378@2|Bacteria,1MV7I@1224|Proteobacteria,1RRN5@1236|Gammaproteobacteria,1X4S3@135614|Xanthomonadales 135614|Xanthomonadales S D5 N terminal like - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5 k59_56419_1 1040986.ATYO01000045_gene2487 4.32e-09 58.2 COG2852@1|root,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,2UFZ7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF559 k59_202976_1 247156.PNF1_1350 4.24e-24 103.0 COG2425@1|root,COG2425@2|Bacteria,2GMHF@201174|Actinobacteria 201174|Actinobacteria S von Willebrand factor (vWF) type A domain - - - - - - - - - - - - VWA_2 k59_202976_11 1303692.SFUL_553 7.86e-08 54.3 2DMIE@1|root,32RSG@2|Bacteria,2IQEH@201174|Actinobacteria 201174|Actinobacteria K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA - - - ko:K18955 - - - - ko00000,ko03000 - - - Whib k59_263279_1 1410631.JHWZ01000001_gene895 5.25e-19 92.0 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1UMUT@1239|Firmicutes,24FBZ@186801|Clostridia,27KXC@186928|unclassified Lachnospiraceae 186801|Clostridia IM Cytidylyltransferase-like - - - - - - - - - - - - CTP_transf_like,PfkB k59_105593_1 153721.MYP_2105 3.7e-13 75.5 COG3325@1|root,COG5276@1|root,COG3325@2|Bacteria,COG5276@2|Bacteria,4PKN2@976|Bacteroidetes,47S6E@768503|Cytophagia 976|Bacteroidetes G NPCBM/NEW2 domain - - - - - - - - - - - - Big_5,CBM_6,LVIVD,NPCBM k59_203138_12 1217710.F969_02563 3.82e-08 55.1 COG5377@1|root,COG5377@2|Bacteria,1MWP8@1224|Proteobacteria,1RN9Q@1236|Gammaproteobacteria,3NIHJ@468|Moraxellaceae 1236|Gammaproteobacteria L YqaJ-like viral recombinase domain - - - - - - - - - - - - YqaJ k59_290022_1 1220717.L7TND1_9VIRU 1.21e-16 84.0 4QAK6@10239|Viruses 10239|Viruses S N-acetylmuramoyl-L-alanine amidase activity - GO:0005575,GO:0018995,GO:0019012,GO:0030430,GO:0033643,GO:0033646,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_117634_3 1123020.AUIE01000007_gene3229 7.22e-54 177.0 2CJWY@1|root,31CWF@2|Bacteria,1RKEF@1224|Proteobacteria,1S75P@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_117634_4 1123020.AUIE01000007_gene3230 5.32e-43 143.0 COG5614@1|root,COG5614@2|Bacteria,1N9Y5@1224|Proteobacteria,1SHES@1236|Gammaproteobacteria 1236|Gammaproteobacteria S head-tail adaptor - - - - - - - - - - - - Phage_H_T_join k59_117634_5 1123020.AUIE01000007_gene3232 4.38e-11 61.2 2EI3E@1|root,33BUW@2|Bacteria,1NGUW@1224|Proteobacteria,1ST4E@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 k59_19560_7 1609634.A0A0C5AFV4_9VIRU 3.51e-35 139.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_263476_3 1121403.AUCV01000002_gene448 7.68e-08 58.5 COG4733@1|root,COG4932@1|root,COG5492@1|root,COG4733@2|Bacteria,COG4932@2|Bacteria,COG5492@2|Bacteria,1QW0V@1224|Proteobacteria,42U6C@68525|delta/epsilon subdivisions,2WQX8@28221|Deltaproteobacteria,2MN90@213118|Desulfobacterales 28221|Deltaproteobacteria M Parallel beta-helix repeats - - - - - - - - - - - - Beta_helix,Big_3_2,DUF4215 k59_384807_1 1123242.JH636435_gene2401 6.9e-06 53.9 2F294@1|root,348UD@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_228016_2 691965.D4P7L5_9CAUD 5.32e-31 113.0 4QG3V@10239|Viruses,4QW5T@35237|dsDNA viruses no RNA stage,4QSWE@28883|Caudovirales,4QM1Q@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_228016_3 691965.D4P7L6_9CAUD 6.07e-56 180.0 4QFKG@10239|Viruses,4QV77@35237|dsDNA viruses no RNA stage,4QR6Q@28883|Caudovirales,4QMGT@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_69754_2 172088.AUGA01000008_gene989 0.000212 49.3 COG0438@1|root,COG0438@2|Bacteria,1MWU0@1224|Proteobacteria,2UAF5@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 k59_251590_1 1123269.NX02_21990 4.39e-34 126.0 COG0863@1|root,COG0863@2|Bacteria,1NQ2A@1224|Proteobacteria,2UJ12@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase k59_251590_2 595537.Varpa_4652 0.000119 45.1 COG1694@1|root,COG1694@2|Bacteria,1N02D@1224|Proteobacteria,2VU39@28216|Betaproteobacteria,4AF54@80864|Comamonadaceae 28216|Betaproteobacteria S PFAM MazG nucleotide pyrophosphohydrolase - - - - - - - - - - - - MazG-like k59_45073_3 313596.RB2501_01256 1.25e-09 60.1 COG3108@1|root,COG3108@2|Bacteria,4NV14@976|Bacteroidetes,1I63W@117743|Flavobacteriia 976|Bacteroidetes S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k59_45073_6 1609634.A0A0C5AFV4_9VIRU 1.09e-154 459.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_263817_1 316274.Haur_1369 2.74e-43 162.0 COG4372@1|root,COG5283@1|root,COG5412@1|root,COG4372@2|Bacteria,COG5283@2|Bacteria,COG5412@2|Bacteria,2G9J0@200795|Chloroflexi 2|Bacteria M TIGRFAM phage tail tape measure protein, TP901 family Z012_10445 - - ko:K01991,ko:K07161,ko:K07484 ko02026,map02026 - - - ko00000,ko00001,ko02000 1.B.18 - - DDE_Tnp_IS66,DUF3084,LZ_Tnp_IS66,PhageMin_Tail,zf-IS66 k59_70160_1 979535.F1D037_9CAUD 1.37e-24 117.0 4QASG@10239|Viruses,4QZZU@35237|dsDNA viruses no RNA stage,4QT37@28883|Caudovirales,4QNXD@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_70160_2 438753.AZC_3584 9.24e-46 157.0 2ATMD@1|root,31J5V@2|Bacteria,1RH31@1224|Proteobacteria,2UBNT@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tail tubular protein - - - - - - - - - - - - Tube k59_301506_1 1150989.H6WXH4_9CAUD 9.73e-19 80.9 4QB6G@10239|Viruses,4QVYX@35237|dsDNA viruses no RNA stage,4QQS8@28883|Caudovirales 28883|Caudovirales S Peptidase M15 - - - - - - - - - - - - - k59_9005_1 1234888.K0A2J2_9VIRU 2.1e-62 207.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_385202_1 411490.ANACAC_00728 2.21e-15 80.9 COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia 186801|Clostridia E Phage tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail k59_301510_1 640511.BC1002_6529 5.6e-82 250.0 28J67@1|root,2Z91Y@2|Bacteria,1R7RG@1224|Proteobacteria,2VRTM@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_337706_1 40373.F991_00514 6.99e-53 173.0 2E66S@1|root,330VB@2|Bacteria,1N0WA@1224|Proteobacteria 1224|Proteobacteria S TIR domain - - - - - - - - - - - - TIR_2 k59_337706_2 335284.Pcryo_2482 6.94e-34 124.0 COG2197@1|root,COG2197@2|Bacteria,1N33D@1224|Proteobacteria,1RZCA@1236|Gammaproteobacteria,3NNFM@468|Moraxellaceae 1236|Gammaproteobacteria KT Primase C terminal 1 (PriCT-1) - - - - - - - - - - - - HTH_23,PriCT_1,Replicase k59_155327_1 1100814.G8FRZ6_9CAUD 4.19e-57 194.0 4QEXX@10239|Viruses,4QZJB@35237|dsDNA viruses no RNA stage,4QTUZ@28883|Caudovirales,4QN8A@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_301513_1 585502.HMPREF0645_2334 1.53e-14 80.9 COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,2FNG7@200643|Bacteroidia 976|Bacteroidetes L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_385205_1 1385658.U5KPZ6_9VIRU 7.38e-61 206.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_216691_1 1114970.PSF113_4313 7.18e-75 257.0 COG4643@1|root,COG5545@1|root,COG4643@2|Bacteria,COG5545@2|Bacteria,1MVGK@1224|Proteobacteria,1S6W2@1236|Gammaproteobacteria,1YSKX@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria S Virulence-associated protein E - - - ko:K06919 - - - - ko00000 - - - Prim-Pol,Toprim_3,Toprim_4,VirE k59_216691_6 985762.SAGN_11317 1.46e-12 65.9 2E3FM@1|root,32YEF@2|Bacteria,1VF4E@1239|Firmicutes,4IRKE@91061|Bacilli 91061|Bacilli S VRR-NUC domain - - - - - - - - - - - - VRR_NUC k59_118056_3 743721.Psesu_1179 1.54e-19 86.3 2DSRK@1|root,33H6U@2|Bacteria,1P21N@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_229161_1 1203076.CAKF01000016_gene1823 1.45e-33 129.0 COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,4HAG5@91061|Bacilli,3F3KU@33958|Lactobacillaceae 91061|Bacilli L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA k59_217358_1 1692257.A0A0K1RL39_9CIRC 7.65e-19 86.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_290784_1 1095743.HMPREF1054_1770 1.41e-45 168.0 COG5511@1|root,COG5511@2|Bacteria,1MVN4@1224|Proteobacteria,1RRK4@1236|Gammaproteobacteria,1Y7IC@135625|Pasteurellales 135625|Pasteurellales S Bacteriophage capsid protein - - - - - - - - - - - - Phage_portal_2 k59_131753_1 1692253.A0A0K1RLM4_9CIRC 4.11e-26 109.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_34447_1 105154.Q9MBU6_9VIRU 6.27e-194 559.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_34447_3 1165094.RINTHH_3920 9.69e-75 238.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_106847_1 279280.Q6J1S4_9CAUD 5.98e-81 258.0 4QG38@10239|Viruses,4QY33@35237|dsDNA viruses no RNA stage,4QQVI@28883|Caudovirales,4QNWM@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_264396_1 1132026.I6NKZ0_9CAUD 7.98e-22 95.5 4QAQV@10239|Viruses,4QUPK@35237|dsDNA viruses no RNA stage,4QPCB@28883|Caudovirales,4QKM5@10699|Siphoviridae 10699|Siphoviridae S sequence-specific DNA binding - - - - - - - - - - - - - k59_82852_2 105154.Q9MBU6_9VIRU 1.07e-67 224.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_240268_2 1609634.A0A0C5AFV4_9VIRU 5.72e-19 86.3 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_143536_1 1539298.JO41_05835 3.53e-10 69.3 COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2J6RF@203691|Spirochaetes 203691|Spirochaetes M LysM domain M23 M37 peptidase domain protein nlpD - - - - - - - - - - - LysM,Peptidase_M23 k59_361946_3 472175.EL18_01406 1.82e-32 131.0 COG3723@1|root,COG3723@2|Bacteria,1R6DB@1224|Proteobacteria,2U82T@28211|Alphaproteobacteria 28211|Alphaproteobacteria L RecT family - - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_277475_2 1609634.A0A0C5AFV4_9VIRU 6.64e-49 174.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_156584_1 1123487.KB892865_gene1391 1.12e-81 259.0 COG0553@1|root,COG0553@2|Bacteria,1PN7I@1224|Proteobacteria,2VP2N@28216|Betaproteobacteria 28216|Betaproteobacteria L Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair - - - - - - - - - - - - SNF2_N k59_46839_2 1120963.KB894496_gene2684 2.28e-07 52.8 COG0807@1|root,COG5113@1|root,COG0807@2|Bacteria,COG3236@2|Bacteria,1MWZR@1224|Proteobacteria,1RMFX@1236|Gammaproteobacteria,2Q1M9@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate ribA GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25 ko:K01497 ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024 M00125 R00425 RC00293,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DUF1768,GTP_cyclohydro2 k59_168022_1 766499.C357_06926 2.21e-71 221.0 COG1192@1|root,COG1192@2|Bacteria,1MWRE@1224|Proteobacteria,2TSJZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria D Cobyrinic acid a,c-diamide synthase parA1 - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k59_168022_3 911045.PSE_0458 2.98e-16 81.3 2D0K9@1|root,32T8S@2|Bacteria,1MZRW@1224|Proteobacteria,2UDZH@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_338895_1 1121285.AUFK01000002_gene17 7.56e-26 113.0 COG0553@1|root,COG0863@1|root,COG0553@2|Bacteria,COG0863@2|Bacteria,4NHHF@976|Bacteroidetes,1I7WE@117743|Flavobacteriia 976|Bacteroidetes L DNA methylase - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_46840_1 313628.LNTAR_03149 9.03e-21 94.4 COG0028@1|root,COG0028@2|Bacteria 2|Bacteria EH Belongs to the TPP enzyme family ilvB2 - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k59_83463_1 1177928.TH2_05053 2.54e-07 53.9 COG4627@1|root,COG4627@2|Bacteria,1PEWU@1224|Proteobacteria,2VD5J@28211|Alphaproteobacteria,2JUMB@204441|Rhodospirillales 204441|Rhodospirillales S Pfam Methyltransferase - - - - - - - - - - - - - k59_83463_4 485914.Hmuk_1218 5.86e-12 63.9 COG1051@1|root,arCOG01075@2157|Archaea,2XYIN@28890|Euryarchaeota,23W6H@183963|Halobacteria 183963|Halobacteria L NUDIX domain - - - ko:K03207 - - - - ko00000,ko01000 - - - NUDIX k59_229862_4 1385658.U5KNR1_9VIRU 3.74e-61 205.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_229862_7 1986029.Q9MBM8_9VIRU 2.39e-32 124.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_189430_2 888059.HMPREF9071_2133 7.38e-42 157.0 COG1783@1|root,COG1783@2|Bacteria,4NHPB@976|Bacteroidetes,1IH79@117743|Flavobacteriia,1ESIH@1016|Capnocytophaga 976|Bacteroidetes S Phage terminase, large subunit, PBSX family - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_10201_1 588596.U9TRZ4 4.3e-08 60.5 2END3@1|root,2SRUK@2759|Eukaryota,3ATWJ@33154|Opisthokonta,3PH88@4751|Fungi 4751|Fungi S Geminivirus Rep catalytic domain - - - - - - - - - - - - Gemini_AL1 k59_144370_1 870187.Thini_0411 1.58e-25 109.0 2EP1Y@1|root,33GNT@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_10203_1 1329516.JPST01000011_gene358 2.43e-08 55.8 COG0270@1|root,COG0270@2|Bacteria,1TPNE@1239|Firmicutes,4HHQR@91061|Bacilli 91061|Bacilli H C-5 cytosine-specific DNA methylase - - - - - - - - - - - - DNA_methylase k59_374658_1 460265.Mnod_6257 3.1e-16 77.4 2DS0Z@1|root,33E0M@2|Bacteria,1NIVH@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_71990_5 469596.HMPREF9488_03270 1.27e-15 74.3 COG0758@1|root,COG0758@2|Bacteria,1VNFT@1239|Firmicutes 1239|Firmicutes LU Protein of unknown function (DUF2493) - - - - - - - - - - - - DUF2493 k59_327461_2 1215092.PA6_009_00300 1.19e-39 143.0 28JC4@1|root,2Z96S@2|Bacteria,1RI8W@1224|Proteobacteria,1S6FI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S P22 coat protein-protein 5 domain protein - - - - - - - - - - - - - k59_386948_1 1192868.CAIU01000008_gene967 1.5e-59 190.0 COG1738@1|root,COG1738@2|Bacteria,1RDSF@1224|Proteobacteria 1224|Proteobacteria S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage - - - ko:K09125 - - - - ko00000 - - - Vut_1 k59_386948_3 1353531.AZNX01000020_gene4384 2.79e-59 189.0 2A4D4@1|root,30SYX@2|Bacteria,1PCIM@1224|Proteobacteria,2USSQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_157341_1 105154.Q9MBU3_9VIRU 4.9e-08 58.9 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_157341_7 1609634.A0A0C5AFT2_9VIRU 1.55e-39 140.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_230474_1 105154.Q9MBU6_9VIRU 5.03e-92 291.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_339518_1 643562.Daes_0328 7.17e-85 270.0 COG5323@1|root,COG5323@2|Bacteria,1R049@1224|Proteobacteria,42UYF@68525|delta/epsilon subdivisions,2WQN3@28221|Deltaproteobacteria,2M90K@213115|Desulfovibrionales 28221|Deltaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6 k59_339518_5 1121456.ATVA01000014_gene640 1.08e-55 202.0 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,42YKK@68525|delta/epsilon subdivisions,2WUDS@28221|Deltaproteobacteria,2M8E7@213115|Desulfovibrionales 28221|Deltaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_47655_1 243090.RB5015 2.19e-30 115.0 COG0454@1|root,COG0456@2|Bacteria,2IZ5N@203682|Planctomycetes 203682|Planctomycetes K Ribosomal-protein-alanine acetyltransferase - - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 k59_47655_2 344747.PM8797T_06105 1.02e-16 73.9 COG1551@1|root,COG1551@2|Bacteria,2J0QX@203682|Planctomycetes 203682|Planctomycetes J Could accelerate the degradation of some genes transcripts potentially through selective RNA binding - - - ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 - - - ko00000,ko00001,ko03019 - - - CsrA k59_265684_1 1463934.JOCF01000064_gene4216 4.06e-45 154.0 COG0270@1|root,COG0270@2|Bacteria,2GNB2@201174|Actinobacteria 201174|Actinobacteria L DNA (cytosine-5-)-methyltransferase activity - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_278308_1 1692257.A0A0K1RL48_9CIRC 8.72e-28 114.0 4QCY8@10239|Viruses,4QUMD@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_182738_2 1166130.H650_06835 2.59e-50 184.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,1RNR0@1236|Gammaproteobacteria,3X3B1@547|Enterobacter 1236|Gammaproteobacteria S Phage portal protein - - - - - - - - - - - - Phage_portal k59_182738_5 1097668.BYI23_B000660 1.61e-10 65.9 COG3740@1|root,COG3740@2|Bacteria,1N2D8@1224|Proteobacteria,2VWTS@28216|Betaproteobacteria,1K7IS@119060|Burkholderiaceae 28216|Betaproteobacteria S Caudovirus prohead serine protease - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78 k59_182738_7 1432056.X781_8120 6.25e-147 437.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1TKGR@1236|Gammaproteobacteria,1Y7SY@135625|Pasteurellales 135625|Pasteurellales S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_377433_1 645099.MREP_BBTVA 4.31e-07 57.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_61591_2 105154.Q9MBU6_9VIRU 7.74e-195 563.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_146550_2 194699.Q775A7_BPBPP 1.02e-14 81.6 4QC5D@10239|Viruses,4QVY9@35237|dsDNA viruses no RNA stage,4QPVU@28883|Caudovirales,4QNN5@10744|Podoviridae 10744|Podoviridae S Protein of unknown function (DUF2800) - - - - - - - - - - - - - k59_304476_1 525254.HMPREF0072_1327 0.000266 48.1 COG1396@1|root,COG1396@2|Bacteria,1VEU8@1239|Firmicutes,24QN0@186801|Clostridia 186801|Clostridia K DNA-binding helix-turn-helix protein - - - - - - - - - - - - HTH_19,HTH_3 k59_49394_3 480808.A8WA16_9CAUD 5.16e-07 55.1 4QAX2@10239|Viruses,4QPIT@28883|Caudovirales,4QMN7@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_340796_1 1476888.X4YGV5_9CAUD 4.21e-08 60.8 4QF5E@10239|Viruses,4R01K@35237|dsDNA viruses no RNA stage,4QS4R@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_328932_2 1234888.K0A2J2_9VIRU 1.62e-21 93.6 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_196103_1 655097.C8ZKG2_9CAUD 9.32e-57 199.0 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_256837_1 1385658.U5KPZ6_9VIRU 1.23e-115 352.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_305601_2 312309.VF_2017 4.78e-37 129.0 2CPEB@1|root,32SIW@2|Bacteria,1MZE0@1224|Proteobacteria,1SARU@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_305601_8 1536597.A0A088F6J4_9CAUD 1.2e-84 265.0 4QAIK@10239|Viruses,4QPEB@28883|Caudovirales,4QP3P@10744|Podoviridae 10744|Podoviridae S phosphoprotein phosphatase activity - - - - - - - - - - - - - k59_329846_2 158500.BV97_05496 4.72e-22 93.2 2CMPB@1|root,32SF8@2|Bacteria,1RCNY@1224|Proteobacteria,2UPH0@28211|Alphaproteobacteria,2K2QJ@204457|Sphingomonadales 204457|Sphingomonadales S Transcription elongation protein SprT - - - - - - - - - - - - - k59_220662_1 1618258.A0A0C5I9K3_9CIRC 7.35e-16 86.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_50304_3 457421.CBFG_05519 0.000122 51.6 COG2946@1|root,COG2946@2|Bacteria,1UHNT@1239|Firmicutes,24ZUP@186801|Clostridia,26C0F@186813|unclassified Clostridiales 186801|Clostridia L Replication initiation factor - - - ko:K07467 - - - - ko00000 - - - HTH_3,Rep_trans k59_159885_1 631362.Thi970DRAFT_01443 0.000121 46.2 COG1396@1|root,COG1396@2|Bacteria,1N1H0@1224|Proteobacteria,1SD1C@1236|Gammaproteobacteria,1WZEF@135613|Chromatiales 135613|Chromatiales K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - - k59_269043_3 1788444.A0A190WHA5_9CIRC 5.58e-19 91.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_135300_2 263358.VAB18032_03440 6.87e-14 75.9 COG0030@1|root,COG0030@2|Bacteria,2I4EV@201174|Actinobacteria,4DDT8@85008|Micromonosporales 201174|Actinobacteria J Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 k59_135300_4 1538295.JY96_16180 6.91e-78 240.0 COG1442@1|root,COG1442@2|Bacteria,1QH4S@1224|Proteobacteria,2VN0S@28216|Betaproteobacteria,1KN5D@119065|unclassified Burkholderiales 28216|Betaproteobacteria M glycosyl transferase family 8 - - - - - - - - - - - - - k59_171908_2 1173029.JH980292_gene811 3.58e-06 55.1 COG0860@1|root,COG0860@2|Bacteria,1G008@1117|Cyanobacteria,1H876@1150|Oscillatoriales 1117|Cyanobacteria M N-acetylmuramoyl-L-alanine amidase amiC - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3 k59_25992_2 489825.LYNGBM3L_59550 3.9e-40 143.0 COG3772@1|root,COG3772@2|Bacteria,1G7YF@1117|Cyanobacteria,1HASB@1150|Oscillatoriales 1117|Cyanobacteria M Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - PG_binding_1,Phage_lysozyme k59_220777_2 1385658.U5KPZ6_9VIRU 4.61e-146 437.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_210028_1 438753.AZC_3583 8.4e-13 73.2 28IA2@1|root,2Z8CQ@2|Bacteria,1PQM2@1224|Proteobacteria,2TUAP@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_27311_1 1239382.K4P021_9CAUD 1.03e-13 77.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNI0@10744|Podoviridae 10744|Podoviridae S viral capsid - GO:0003674,GO:0005488,GO:0005515,GO:0042802 - - - - - - - - - - - k59_197432_1 1524880.A0A076G697_9VIRU 1.01e-08 61.2 4QD1M@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_197432_5 1524880.A0A076G7N6_9VIRU 3.18e-101 331.0 4QAUF@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_197432_6 1524880.A0A076G6J2_9VIRU 2.76e-155 453.0 4QD9Y@10239|Viruses 10239|Viruses S Pfam:Terminase_6C - - - - - - - - - - - - - k59_173140_1 1692255.A0A0K1RL52_9CIRC 9.9e-21 97.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_112260_1 1609634.A0A0C5AFV4_9VIRU 4.44e-61 203.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_112260_3 1609634.A0A0C5ANA6_9VIRU 4.79e-13 73.2 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_197433_1 1458860.A0A088C4U4_9CAUD 4.79e-20 90.1 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QII1@10662|Myoviridae 10662|Myoviridae S N-methyltransferase activity - - - - - - - - - - - - - k59_245769_1 182217.HCW_02255 6.12e-15 77.8 COG0863@1|root,COG1092@1|root,COG0863@2|Bacteria,COG1092@2|Bacteria,1NXST@1224|Proteobacteria,42Q3Q@68525|delta/epsilon subdivisions,2YN8U@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_14269_1 1121447.JONL01000001_gene569 1.71e-149 442.0 COG5362@1|root,COG5362@2|Bacteria,1PYY9@1224|Proteobacteria,435M3@68525|delta/epsilon subdivisions,2WZZT@28221|Deltaproteobacteria,2M981@213115|Desulfovibrionales 28221|Deltaproteobacteria S TIGRFAM Phage - - - - - - - - - - - - - k59_294605_2 1234888.K0A2J2_9VIRU 5.59e-132 398.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_306915_1 1211777.BN77_4171 0.000126 48.9 2DWRQ@1|root,341KN@2|Bacteria,1NYD8@1224|Proteobacteria,2UTQ9@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_233917_2 1788438.A0A190WHE1_9CIRC 1.55e-15 82.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_75844_2 1231190.NA8A_23409 2.49e-25 100.0 COG4122@1|root,COG4122@2|Bacteria,1QWQR@1224|Proteobacteria,2TX2B@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Methyltransferase domain - - - - - - - - - - - - Methyltransf_24 k59_14277_2 1115653.S5M7Q8_9CAUD 1.45e-31 128.0 4QBNM@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPUI@28883|Caudovirales,4QNGU@10744|Podoviridae 10744|Podoviridae S serine-type endopeptidase activity - - - - - - - - - - - - - k59_126047_1 1033737.CAEV01000001_gene2354 2.18e-13 79.0 2EYIP@1|root,33RSF@2|Bacteria,1VSNU@1239|Firmicutes,24YEW@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_65279_1 1288826.MSNKSG1_16851 1.31e-06 62.8 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,Response_reg k59_247165_1 1618236.A0A0C5I2F3_9CIRC 7.78e-39 147.0 4QGVY@10239|Viruses,4QUKN@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_52926_1 582899.Hden_2973 7.58e-11 63.5 2CK39@1|root,32SBG@2|Bacteria,1MZ6F@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - Phage_connect_1 k59_259268_2 1379722.S5SY31_9CIRC 8.32e-19 85.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_101664_1 57918.XP_004304185.1 9.04e-86 302.0 COG1073@1|root,COG5108@1|root,KOG1038@2759|Eukaryota,KOG1552@2759|Eukaryota,37Q9S@33090|Viridiplantae,3G82K@35493|Streptophyta,4JDS9@91835|fabids 35493|Streptophyta K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates - GO:0000428,GO:0000959,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006351,GO:0006390,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034245,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0098798,GO:0140053,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K10908 - - - - ko00000,ko01000,ko03029 - - - RNA_pol,RPOL_N k59_52929_2 1385658.U5KNR1_9VIRU 5.41e-78 246.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_356787_1 278957.ABEA03000004_gene4552 4.14e-57 204.0 COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,46Y61@74201|Verrucomicrobia,3K8ZZ@414999|Opitutae 414999|Opitutae KL DEAD-like helicases superfamily - - - - - - - - - - - - ResIII k59_40585_1 439375.Oant_1547 1.11e-47 180.0 COG0464@1|root,COG0464@2|Bacteria 2|Bacteria O ATPase activity - - - ko:K06883 - - - - ko00000 - - - AAA,Mrr_cat k59_381133_1 1609634.A0A0C5AFT2_9VIRU 2.21e-17 85.5 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_296080_1 1121106.JQKB01000016_gene5268 1.33e-35 137.0 COG0500@1|root,COG2520@1|root,COG2226@2|Bacteria,COG2520@2|Bacteria,1RIYU@1224|Proteobacteria,2U2ZF@28211|Alphaproteobacteria,2JSTB@204441|Rhodospirillales 204441|Rhodospirillales Q Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 k59_285217_1 504346.TMP_BPPAJ 7.73e-18 88.2 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - GO:0008150,GO:0044403,GO:0044409,GO:0044411,GO:0044419,GO:0051701,GO:0051704,GO:0051828,GO:0051830,GO:0085027 - - - - - - - - - - - k59_126248_1 1609634.A0A0C5AFV4_9VIRU 3.41e-49 173.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_126248_3 1609634.A0A0C5AFT2_9VIRU 1.14e-55 189.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_198804_5 1211640.K4K619_9CAUD 2e-11 65.5 4QHHF@10239|Viruses,4QVRF@35237|dsDNA viruses no RNA stage,4QRG3@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_198804_6 462590.A9J500_BPPYU 8.74e-110 337.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_42051_1 1385658.U5KPZ6_9VIRU 1.81e-28 114.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_382340_2 246200.SPO3258 6.72e-05 52.8 COG3757@1|root,COG3757@2|Bacteria,1N792@1224|Proteobacteria,2TVI6@28211|Alphaproteobacteria,4NBP4@97050|Ruegeria 28211|Alphaproteobacteria M Glycosyl hydrolases family 25 lyc - - ko:K07273 - - - - ko00000 - - - Glyco_hydro_25 k59_382340_7 1206741.BAFX01000172_gene7413 1.61e-08 57.8 2CICW@1|root,346YY@2|Bacteria,2HIJU@201174|Actinobacteria,4G48K@85025|Nocardiaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_248785_1 240016.ABIZ01000001_gene5053 7.76e-09 66.2 2DR7Z@1|root,33AM6@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_151794_1 1121272.KB903272_gene517 3.96e-10 59.7 COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,4DDNH@85008|Micromonosporales 201174|Actinobacteria F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase k59_114968_1 1499683.CCFF01000005_gene42 8.61e-19 81.3 2DRJA@1|root,33C0M@2|Bacteria,1VKIR@1239|Firmicutes,24VD8@186801|Clostridia,36P5U@31979|Clostridiaceae 186801|Clostridia S Domain of Unknown Function with PDB structure (DUF3850) - - - - - - - - - - - - DUF3850 k59_6079_1 399742.Ent638_4279 5.35e-20 95.1 28H9R@1|root,2Z7MD@2|Bacteria,1MVTR@1224|Proteobacteria,1RMPH@1236|Gammaproteobacteria,3X0IF@547|Enterobacter 1236|Gammaproteobacteria S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_54444_1 1140001.I571_01849 1.97e-20 85.5 2EK5K@1|root,33DW0@2|Bacteria,1VKGK@1239|Firmicutes,4HRYF@91061|Bacilli,4B4AI@81852|Enterococcaceae 91061|Bacilli S Putative phage holin Dp-1 - - - - - - - - - - - - Phage_holin_Dp1 k59_91416_2 1527515.A0A088FB58_9CAUD 1.32e-55 199.0 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - GO:0008150,GO:0044403,GO:0044409,GO:0044411,GO:0044419,GO:0051701,GO:0051704,GO:0051828,GO:0051830,GO:0085027 - - - - - - - - - - - k59_54448_1 1385658.U5KPZ6_9VIRU 1.76e-51 183.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_370002_1 145579.CAPSD_BPPHM 2.41e-63 216.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_186294_2 502558.EGYY_19930 3.97e-18 93.2 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4CUSF@84998|Coriobacteriia 84998|Coriobacteriia L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A k59_43862_5 1410624.JNKK01000045_gene546 1.31e-11 72.0 COG1511@1|root,COG4675@1|root,COG1511@2|Bacteria,COG4675@2|Bacteria,1V943@1239|Firmicutes,24PFY@186801|Clostridia 186801|Clostridia S PFAM Tail Collar domain protein - - - - - - - - - - - - Collar k59_153641_1 573174.M4MHJ9_9VIRU 4.76e-31 120.0 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage 10239|Viruses S bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity - - - - - - - - - - - - - k59_153641_3 573174.M4MCV1_9VIRU 6.35e-52 181.0 4QAKZ@10239|Viruses,4QUSW@35237|dsDNA viruses no RNA stage 10239|Viruses S N-acetyltransferase activity - - - - - - - - - - - - - k59_141209_1 1123487.KB892865_gene1380 4.02e-54 189.0 COG3170@1|root,COG3170@2|Bacteria,1PMRK@1224|Proteobacteria,2W7ZG@28216|Betaproteobacteria,2KZB6@206389|Rhodocyclales 206389|Rhodocyclales NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - k59_18479_1 1144664.F973_00712 0.000248 49.7 COG0358@1|root,COG5519@1|root,COG0358@2|Bacteria,COG5519@2|Bacteria,1MW5H@1224|Proteobacteria,1RQ7H@1236|Gammaproteobacteria,3NSKI@468|Moraxellaceae 1236|Gammaproteobacteria L Domain of unknown function (DUF927) Z012_01240 - - ko:K06919 - - - - ko00000 - - - DUF927,Prim_Zn_Ribbon,Toprim_3 k59_299692_2 1788445.A0A190WHA3_9CIRC 1.03e-20 90.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_104680_1 1788444.A0A190WHA5_9CIRC 8.26e-19 90.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_104680_3 1379709.S5TMV0_9CIRC 9.72e-21 91.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_43866_1 105154.Q9MBU3_9VIRU 1.66e-11 68.9 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_43866_2 1609634.A0A0C5AFV4_9VIRU 2.99e-10 60.5 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_68577_1 1283077.M1I7J8_9CAUD 3.86e-57 196.0 4QCWX@10239|Viruses,4QW0V@35237|dsDNA viruses no RNA stage,4QR4Y@28883|Caudovirales,4QP36@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_226880_1 1268072.PSAB_06080 1.13e-27 117.0 2ENRS@1|root,32H5X@2|Bacteria,1U0J9@1239|Firmicutes,4I9Y7@91061|Bacilli,2724K@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - k59_68579_1 1034809.SLUG_08450 1.03e-17 85.5 COG3935@1|root,COG3935@2|Bacteria,1TSHD@1239|Firmicutes,4HIGY@91061|Bacilli,4GYXQ@90964|Staphylococcaceae 91061|Bacilli L Conserved phage C-terminus (Phg_2220_C) - - - - - - - - - - - - Phage_rep_org_N,Phg_2220_C k59_215189_1 378806.STAUR_6166 5.73e-26 115.0 COG5545@1|root,COG5545@2|Bacteria,1MVGK@1224|Proteobacteria 1224|Proteobacteria D virulence-associated E family protein - - - ko:K06919 - - - - ko00000 - - - PriCT_2,Prim-Pol,Toprim_3,VirE k59_165725_1 1217712.F971_02001 5.7e-36 132.0 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,1SA7C@1236|Gammaproteobacteria,3NSKU@468|Moraxellaceae 1236|Gammaproteobacteria G Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - PG_binding_1,Phage_lysozyme k59_227049_2 665950.HMPREF1025_01961 1.12e-146 429.0 COG0553@1|root,COG0553@2|Bacteria,1TS9W@1239|Firmicutes,24CGX@186801|Clostridia 186801|Clostridia KL Helicase conserved C-terminal domain - - - - - - - - - - - - - k59_383861_2 105154.Q9MBU3_9VIRU 2.57e-12 70.5 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_227050_1 1197951.I6S6K3_9CAUD 7.59e-09 67.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_118203_1 794846.AJQU01000075_gene3389 1.82e-27 104.0 2EK9X@1|root,33E07@2|Bacteria,1NP0D@1224|Proteobacteria,2UJQX@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_20344_1 1121441.AUCX01000032_gene3179 4.45e-49 186.0 COG0503@1|root,COG0827@1|root,COG0503@2|Bacteria,COG0827@2|Bacteria,1QZ6D@1224|Proteobacteria,42Z8W@68525|delta/epsilon subdivisions,2WU49@28221|Deltaproteobacteria,2MAY9@213115|Desulfovibrionales 28221|Deltaproteobacteria LMNU Methyltransferase small domain - - - - - - - - - - - - MTS k59_155687_2 1234888.K0A2J2_9VIRU 1.13e-116 355.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_276625_2 573174.M4MBC1_9VIRU 8.67e-61 202.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage 10239|Viruses S N-methyltransferase activity - - - - - - - - - - - - - k59_301857_1 278957.ABEA03000174_gene3380 5.74e-06 48.9 2C4D9@1|root,337PW@2|Bacteria,46YN8@74201|Verrucomicrobia,3K9VC@414999|Opitutae 414999|Opitutae S Protein of unknown function (DUF1353) - - - - - - - - - - - - DUF1353 k59_106574_1 1788454.A0A190WHE4_9CIRC 1.18e-50 172.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_217076_2 261292.Nit79A3_2410 2.57e-39 149.0 COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,2VRW1@28216|Betaproteobacteria,374AK@32003|Nitrosomonadales 28216|Betaproteobacteria S TIGRFAM phage portal protein, HK97 - - - - - - - - - - - - Phage_portal k59_239991_1 411460.RUMTOR_01335 7.27e-12 73.2 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_239991_2 665950.HMPREF1025_02008 9.68e-17 79.7 COG4722@1|root,COG4722@2|Bacteria,1TWDJ@1239|Firmicutes,25AUH@186801|Clostridia,27SSX@186928|unclassified Lachnospiraceae 186801|Clostridia S Phage tail protein - - - - - - - - - - - - Sipho_tail k59_143290_1 1283299.AUKG01000001_gene1988 1.73e-05 51.6 COG4122@1|root,COG4122@2|Bacteria 2|Bacteria E O-methyltransferase activity - - - - - - - - - - - - Methyltransf_24,TylF k59_180237_3 312309.VF_2017 3.38e-20 85.1 2CPEB@1|root,32SIW@2|Bacteria,1MZE0@1224|Proteobacteria,1SARU@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_20364_1 1385658.U5KPZ6_9VIRU 3.54e-110 335.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_351583_1 1348114.OM33_08535 2.45e-31 130.0 COG1196@1|root,COG2911@1|root,COG1196@2|Bacteria,COG2911@2|Bacteria 2|Bacteria S protein secretion lgt - - ko:K09800,ko:K13735 ko05100,map05100 - - - ko00000,ko00001,ko02000 - - - PhageMin_Tail k59_157520_2 530564.Psta_2248 5.6e-27 107.0 COG3566@1|root,COG3566@2|Bacteria 2|Bacteria S Uncharacterized protein conserved in bacteria (DUF2213) - - - - - - - - - - - - DUF2213 k59_230705_1 188350.Q8H9W3_9CAUD 7.32e-05 49.7 4QE8X@10239|Viruses,4QYGD@35237|dsDNA viruses no RNA stage,4QRJF@28883|Caudovirales,4QNB2@10744|Podoviridae 10744|Podoviridae S Phage phiEco32-like COOH.NH2 ligase-type 2 - - - - - - - - - - - - - k59_181805_4 478749.BRYFOR_08531 6.9e-17 77.4 2CGGA@1|root,345NF@2|Bacteria,1VZU0@1239|Firmicutes,253ZW@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_181805_5 691965.D4P7C0_9CAUD 8.52e-55 175.0 4QDUR@10239|Viruses,4QVMY@35237|dsDNA viruses no RNA stage,4QU8R@28883|Caudovirales,4QKNQ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_181805_9 1122176.KB903532_gene2562 3.75e-09 62.8 COG2931@1|root,COG5295@1|root,COG2931@2|Bacteria,COG5295@2|Bacteria,4NF3S@976|Bacteroidetes,1ISQ8@117747|Sphingobacteriia 976|Bacteroidetes UW domain, Protein - - - - - - - - - - - - Collagen,Peptidase_S74 k59_181805_12 1156844.KB891809_gene7935 7.24e-17 91.7 COG0791@1|root,COG3409@1|root,COG0791@2|Bacteria,COG3409@2|Bacteria,2I61A@201174|Actinobacteria 201174|Actinobacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - NLPC_P60,PG_binding_1 k59_22082_3 1117318.PRUB_08799 6.09e-18 80.1 COG3772@1|root,COG3772@2|Bacteria,1N0ZQ@1224|Proteobacteria,1S9AE@1236|Gammaproteobacteria,2Q38I@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_72251_1 438753.AZC_3583 2.52e-31 129.0 28IA2@1|root,2Z8CQ@2|Bacteria,1PQM2@1224|Proteobacteria,2TUAP@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_145162_1 359.CN09_09380 2.37e-36 139.0 COG0553@1|root,COG0553@2|Bacteria,1R7CK@1224|Proteobacteria,2U228@28211|Alphaproteobacteria,4BN0G@82115|Rhizobiaceae 28211|Alphaproteobacteria KL DNA methylase N-4 - - - - - - - - - - - - Helicase_C,N6_N4_Mtase k59_327687_1 1121033.AUCF01000044_gene4597 0.000869 47.8 COG0457@1|root,COG0457@2|Bacteria,1MUZK@1224|Proteobacteria,2TS0U@28211|Alphaproteobacteria,2JPRT@204441|Rhodospirillales 204441|Rhodospirillales M Tetratricopeptide repeat - - - - - - - - - - - - Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8 k59_278355_2 1530454.A0A076JTZ1_9CIRC 4.11e-14 79.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_47862_6 1141136.K4F786_9CAUD 3.68e-24 106.0 4QAUT@10239|Viruses,4QVIM@35237|dsDNA viruses no RNA stage,4QQ7X@28883|Caudovirales,4QIGV@10662|Myoviridae 10662|Myoviridae S DNA ligase (ATP) activity - - - - - - - - - - - - - k59_230845_1 105154.Q9MBU6_9VIRU 6.3e-48 171.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_303668_1 1122132.AQYH01000015_gene2278 1.87e-12 74.7 COG4675@1|root,COG4675@2|Bacteria,1N9JB@1224|Proteobacteria,2UIAU@28211|Alphaproteobacteria 28211|Alphaproteobacteria S tail collar domain protein - - - - - - - - - - - - - k59_60121_2 1395516.PMO01_05045 1.74e-16 74.3 2D7I9@1|root,32TP3@2|Bacteria,1N2ZM@1224|Proteobacteria,1S9DB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S phage protein ybcO - - - - - - - - - - - DUF1364 k59_241979_2 52598.EE36_07643 2.08e-09 63.9 28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TWC3@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_387394_1 1423144.Gal_02288 2.39e-29 112.0 COG1403@1|root,COG1403@2|Bacteria,1N0FM@1224|Proteobacteria,2TWQN@28211|Alphaproteobacteria 28211|Alphaproteobacteria V ERF superfamily - - - - - - - - - - - - ERF k59_387394_2 1484157.PSNIH2_21350 1.5e-40 143.0 COG4262@1|root,COG4262@2|Bacteria,1QIFV@1224|Proteobacteria,1TGA7@1236|Gammaproteobacteria,3W1JM@53335|Pantoea 1236|Gammaproteobacteria S Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - - - - - - - - - - - k59_254337_1 411465.PEPMIC_00744 8.64e-09 62.8 COG1196@1|root,COG5412@1|root,COG1196@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia,22HH1@1570339|Peptoniphilaceae 186801|Clostridia D Phage tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail k59_351730_1 32057.KB217478_gene2118 7.05e-17 93.2 COG0484@1|root,COG1061@1|root,COG0484@2|Bacteria,COG1061@2|Bacteria,1G2HP@1117|Cyanobacteria 2|Bacteria L Type III restriction enzyme res subunit - - - ko:K03686,ko:K05516 - - - - ko00000,ko03029,ko03036,ko03110 - - - DnaJ,DnaJ_C,Helicase_C,ResIII k59_145886_2 641149.HMPREF9016_01178 1.12e-05 47.4 2EI4V@1|root,33BW7@2|Bacteria,1R1BA@1224|Proteobacteria 1224|Proteobacteria S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_24345_1 525257.HMPREF0204_14084 6.62e-29 129.0 COG0553@1|root,COG0553@2|Bacteria,4NG6P@976|Bacteroidetes,1HZUG@117743|Flavobacteriia,3ZNSK@59732|Chryseobacterium 976|Bacteroidetes L DNA helicase - - - - - - - - - - - - Helicase_C,SNF2_N,SNF2_assoc k59_230944_4 186617.M9M8L2_9VIRU 1.33e-90 291.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_230944_6 1385658.U5KNR1_9VIRU 2.08e-49 175.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_316023_3 1986029.Q9MBM8_9VIRU 4.02e-154 460.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_328153_4 1002672.SAR11G3_01288 8.45e-45 151.0 2AV7S@1|root,31KYE@2|Bacteria,1RKQ6@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_328153_7 1236000.L0AQQ6_9CAUD 3.09e-61 213.0 4QB9Y@10239|Viruses,4QWGZ@35237|dsDNA viruses no RNA stage,4QPTT@28883|Caudovirales,4QJD7@10662|Myoviridae 10662|Myoviridae S hydrolase activity - - - - - - - - - - - - - k59_243117_1 105154.Q9MBU6_9VIRU 1.39e-54 186.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_243117_4 1385658.U5KNR1_9VIRU 2.54e-55 187.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_243117_6 1385658.U5KPZ6_9VIRU 7.96e-147 434.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_194513_1 111105.HR09_00645 2.8e-07 52.4 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,2FM8X@200643|Bacteroidia,22WNP@171551|Porphyromonadaceae 976|Bacteroidetes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_230948_1 1064535.MELS_0539 1.06e-05 53.9 COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,4H2P0@909932|Negativicutes 909932|Negativicutes K Belongs to the ParB family spo0J - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_280022_17 760568.Desku_2077 0.000458 47.8 COG0500@1|root,COG2226@2|Bacteria,1UY28@1239|Firmicutes,24GXH@186801|Clostridia,262Q6@186807|Peptococcaceae 186801|Clostridia Q Nodulation protein S (NodS) - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 k59_280022_20 932213.SPM24T3_23642 1.68e-29 109.0 COG5614@1|root,COG5614@2|Bacteria,1N9Y5@1224|Proteobacteria,1SE8T@1236|Gammaproteobacteria,405JB@613|Serratia 1236|Gammaproteobacteria S COG5614 Bacteriophage head-tail adaptor - - - - - - - - - - - - Phage_H_T_join k59_280022_21 1439940.BAY1663_02344 5.15e-32 116.0 2EI3E@1|root,33BUW@2|Bacteria,1NGUW@1224|Proteobacteria,1ST4E@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 k59_280022_22 932213.SPM24T3_23272 2.84e-35 132.0 COG4695@1|root,COG4695@2|Bacteria,1N389@1224|Proteobacteria,1SNRA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Portal protein - - - - - - - - - - - - - k59_280022_23 1218084.BBJK01000077_gene5333 1e-161 472.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2VP7E@28216|Betaproteobacteria,1KFK1@119060|Burkholderiaceae 28216|Betaproteobacteria S Phage portal protein - - - - - - - - - - - - Phage_portal k59_280022_25 371042.NG99_26210 5.69e-200 583.0 COG3740@1|root,COG4653@1|root,COG3740@2|Bacteria,COG4653@2|Bacteria,1Q3BS@1224|Proteobacteria,1S17W@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_280022_26 1123020.AUIE01000007_gene3237 1.07e-159 466.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1RPEK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase - - - - - - - - - - - - Terminase_1 k59_49140_1 766499.C357_20220 2.65e-23 99.0 COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria 28211|Alphaproteobacteria S ATP-binding protein' - - - - - - - - - - - - Terminase_6,Terminase_6C k59_377155_1 1122175.ATXU01000006_gene1939 5.84e-08 53.9 COG4570@1|root,COG4570@2|Bacteria,2GQT6@201174|Actinobacteria 201174|Actinobacteria L Endodeoxyribonuclease RusA - - - - - - - - - - - - RusA k59_85567_2 1166016.W5S_2328 6.4e-79 250.0 2CI0W@1|root,2Z81W@2|Bacteria,1R9FZ@1224|Proteobacteria,1S0NA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage X family - - - - - - - - - - - - Phage_CRI,Phage_X k59_207119_2 742767.HMPREF9456_03342 1.54e-08 56.2 COG1403@1|root,COG1403@2|Bacteria 2|Bacteria V endonuclease activity - - - ko:K07451 - - - - ko00000,ko01000,ko02048 - - - HNH k59_121936_1 1548903.A0A0A1IWQ8_9CAUD 4.14e-22 97.1 4QAIK@10239|Viruses,4QPEB@28883|Caudovirales 28883|Caudovirales S phosphoprotein phosphatase activity - - - - - - - - - - - - - k59_109782_1 1415780.JPOG01000001_gene1744 1.29e-16 86.3 COG0454@1|root,COG0827@1|root,COG1040@1|root,COG3087@1|root,COG0456@2|Bacteria,COG0827@2|Bacteria,COG1040@2|Bacteria,COG3087@2|Bacteria,1PI1K@1224|Proteobacteria,1T6BU@1236|Gammaproteobacteria,1XB7I@135614|Xanthomonadales 135614|Xanthomonadales D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - - - - - - - - - - - k59_292051_1 1385658.U5KPZ6_9VIRU 8.95e-186 538.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_316389_1 1391027.T1YRW7_9VIRU 1.19e-16 84.3 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_328591_1 160488.PP_2273 8.48e-70 236.0 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,1SJP1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA polymerase family A - - - - - - - - - - - - DNA_pol_A k59_243293_8 1120985.AUMI01000019_gene2252 3.66e-34 134.0 COG5377@1|root,COG5377@2|Bacteria,1TS2Y@1239|Firmicutes,4H426@909932|Negativicutes 909932|Negativicutes L YqaJ viral recombinase family protein - - - - - - - - - - - - YqaJ k59_243293_9 760568.Desku_0904 9.47e-26 112.0 2EI39@1|root,33BUS@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_243293_10 1396418.BATQ01000046_gene6174 7.24e-14 75.1 2CHG1@1|root,32YZS@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_243293_15 335543.Sfum_1872 1.68e-19 85.9 2AD08@1|root,312N7@2|Bacteria,1NDC4@1224|Proteobacteria,42VQI@68525|delta/epsilon subdivisions,2WS8T@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_243293_18 1346330.M472_21355 9.74e-30 112.0 2DMYE@1|root,32UDK@2|Bacteria,4P1A5@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - k59_243293_20 903818.KI912269_gene35 7.22e-10 67.0 COG0823@1|root,COG4676@1|root,COG0823@2|Bacteria,COG4676@2|Bacteria 2|Bacteria UW Protein conserved in bacteria - - - - - - - - - - - - DUF3253,UPF0560 k59_1092_3 1795991.A0A140CTS1_9CIRC 9.06e-07 54.3 4QHM9@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_377847_1 401053.AciPR4_3094 3.93e-60 197.0 COG0270@1|root,COG0270@2|Bacteria,3Y5V5@57723|Acidobacteria,2JNSG@204432|Acidobacteriia 204432|Acidobacteriia L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_25309_2 1158614.I592_02317 2.22e-06 49.3 2EK5K@1|root,33DW0@2|Bacteria,1VKGK@1239|Firmicutes,4HRYF@91061|Bacilli,4B4AI@81852|Enterococcaceae 91061|Bacilli S Putative phage holin Dp-1 - - - - - - - - - - - - Phage_holin_Dp1 k59_256208_3 1609634.A0A0C5ANA6_9VIRU 1.09e-17 84.3 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_49770_1 1280001.BAOA01000081_gene3007 1.17e-21 88.2 2EVSB@1|root,33P68@2|Bacteria,1P3SK@1224|Proteobacteria,1SS80@1236|Gammaproteobacteria,1XYJ3@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1353) - - - - - - - - - - - - DUF1353 k59_49770_3 1325372.N0DPG8_9CAUD 9.73e-13 71.2 4QBHW@10239|Viruses,4QW8N@35237|dsDNA viruses no RNA stage,4QTT7@28883|Caudovirales,4QJZQ@10662|Myoviridae 10662|Myoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_49770_4 205914.HS_1385 5.89e-47 176.0 COG1783@1|root,COG1783@2|Bacteria,1RAGC@1224|Proteobacteria 1224|Proteobacteria S phage Terminase large subunit - - - - - - - - - - - - - k59_37588_2 1527506.A0A088FBX6_9CAUD 1.78e-15 79.3 4QCM5@10239|Viruses,4QQFH@28883|Caudovirales,4QNDH@10744|Podoviridae 10744|Podoviridae S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_159215_6 655097.C8ZKG3_9CAUD 1.13e-89 272.0 4QEMD@10239|Viruses,4R0JN@35237|dsDNA viruses no RNA stage,4QUGF@28883|Caudovirales,4QNXF@10744|Podoviridae 10744|Podoviridae S AAA domain - - - - - - - - - - - - - k59_159215_7 490913.C4NTD5_9CAUD 3.98e-210 615.0 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_159215_8 490913.C4NTD3_9CAUD 6.57e-11 62.8 4QEG2@10239|Viruses,4QVSD@35237|dsDNA viruses no RNA stage,4QRJ9@28883|Caudovirales,4QP0R@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_244015_3 1217705.F900_01843 2.15e-24 115.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,1S0Q1@1236|Gammaproteobacteria,3NQUM@468|Moraxellaceae 1236|Gammaproteobacteria L DNA polymerase family A - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_341264_3 1283077.M1INZ1_9CAUD 2.7e-72 247.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales,4QNDH@10744|Podoviridae 10744|Podoviridae S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_377944_1 1429767.W6AR86_9CAUD 8.02e-39 145.0 4QEQT@10239|Viruses,4QYJH@35237|dsDNA viruses no RNA stage,4QQ1B@28883|Caudovirales,4QNPW@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_49897_1 1219049.SP5_035_01180 5.21e-27 120.0 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,2TT3N@28211|Alphaproteobacteria,2K7A3@204457|Sphingomonadales 204457|Sphingomonadales S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_256326_1 1122247.C731_3016 2.84e-111 333.0 2A0ZI@1|root,30P4U@2|Bacteria,2IBKD@201174|Actinobacteria,23DBE@1762|Mycobacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_353757_1 114615.BRADO3645 9.62e-08 55.1 COG0791@1|root,COG0791@2|Bacteria,1N732@1224|Proteobacteria,2UH6X@28211|Alphaproteobacteria,3K18Y@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M NlpC/P60 family - - - - - - - - - - - - NLPC_P60 k59_122819_1 1380356.JNIK01000013_gene4367 5.09e-05 50.1 COG1158@1|root,COG1158@2|Bacteria 2|Bacteria K DNA-templated transcription, termination rho GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K02887,ko:K03628 ko03010,ko03018,map03010,map03018 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind k59_37597_1 105154.Q9MBU3_9VIRU 3.99e-09 61.6 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_123912_2 1121447.JONL01000007_gene1400 3.47e-06 53.5 2EP8M@1|root,33GVD@2|Bacteria,1NI3X@1224|Proteobacteria,436AD@68525|delta/epsilon subdivisions,2X0VB@28221|Deltaproteobacteria,2MDHN@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_63170_2 1379695.S5TNA9_9CIRC 3.22e-37 142.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_282338_4 1235661.K0IK58_9CAUD 1.94e-34 131.0 4QNC3@10744|Podoviridae 10744|Podoviridae S endonuclease activity - - - - - - - - - - - - - k59_196689_1 948071.S4S2N2_9CAUD 8.23e-74 237.0 4QH10@10239|Viruses,4QVVN@35237|dsDNA viruses no RNA stage,4QSY9@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_87192_1 691965.D4P7D6_9CAUD 2.67e-54 192.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_244930_1 1692242.A0A0K1RL37_9CIRC 1.05e-35 131.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_111487_1 105154.Q9MBU6_9VIRU 5.27e-160 469.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_111487_7 2003327.CAPSD_BPCHP 1.3e-49 173.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_13594_1 1986029.Q9MBM3_9VIRU 3.29e-22 102.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_13594_4 1385658.U5KPZ6_9VIRU 6.12e-195 560.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_75022_1 428125.CLOLEP_01409 2.15e-68 224.0 COG4626@1|root,COG4626@2|Bacteria,1TT9I@1239|Firmicutes,24AFK@186801|Clostridia,3WNF4@541000|Ruminococcaceae 186801|Clostridia S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_75023_1 1465639.A0A060BH36_9CAUD 4.1e-22 99.8 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_269392_1 1165094.RINTHH_3920 1.44e-40 146.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_111496_1 1609634.A0A0C5AFV4_9VIRU 1.59e-08 55.1 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_306073_1 1234888.K0A2J2_9VIRU 5.78e-46 165.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_244941_1 1692249.A0A0K1RL40_9CIRC 1.21e-05 52.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_306150_2 1003200.AXXA_28010 4.89e-24 103.0 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,2VU8A@28216|Betaproteobacteria,3T6RG@506|Alcaligenaceae 28216|Betaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_161314_1 1297863.APJF01000025_gene2996 1.36e-19 93.2 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,2U0EG@28211|Alphaproteobacteria,3JXF7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6C k59_283672_2 272568.GDI3580 3.34e-08 58.5 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2TS2G@28211|Alphaproteobacteria,2JQ5C@204441|Rhodospirillales 204441|Rhodospirillales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k59_258271_1 1379708.S5SYC3_9CIRC 2.22e-33 128.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_210172_5 1234888.K0A2J2_9VIRU 6.22e-78 259.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_173522_1 11082.PRO_0000037753 1.77e-128 391.0 4QBXT@10239|Viruses,4R138@439488|ssRNA viruses,4R0R1@35278|ssRNA positive-strand viruses no DNA stage 10239|Viruses K ATP-dependent helicase activity - GO:0000122,GO:0001172,GO:0001510,GO:0001558,GO:0001817,GO:0001818,GO:0001932,GO:0001933,GO:0001934,GO:0001959,GO:0001960,GO:0001961,GO:0002039,GO:0002673,GO:0002674,GO:0002682,GO:0002683,GO:0002694,GO:0002695,GO:0002697,GO:0002698,GO:0002791,GO:0002792,GO:0002831,GO:0002832,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003725,GO:0003727,GO:0003824,GO:0003968,GO:0004175,GO:0004252,GO:0004483,GO:0005102,GO:0005124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005793,GO:0006139,GO:0006355,GO:0006357,GO:0006396,GO:0006417,GO:0006508,GO:0006725,GO:0006807,GO:0006810,GO:0006897,GO:0006898,GO:0007155,GO:0007159,GO:0008104,GO:0008134,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008174,GO:0008233,GO:0008236,GO:0008270,GO:0008284,GO:0008285,GO:0008757,GO:0009058,GO:0009059,GO:0009451,GO:0009452,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010562,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010639,GO:0010646,GO:0010647,GO:0010648,GO:0010692,GO:0010694,GO:0010803,GO:0010804,GO:0010821,GO:0010823,GO:0010921,GO:0010922,GO:0010941,GO:0015031,GO:0015833,GO:0016020,GO:0016032,GO:0016070,GO:0016071,GO:0016192,GO:0016462,GO:0016556,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017016,GO:0017111,GO:0017137,GO:0017151,GO:0017171,GO:0018130,GO:0018995,GO:0019048,GO:0019049,GO:0019050,GO:0019054,GO:0019056,GO:0019058,GO:0019065,GO:0019068,GO:0019080,GO:0019082,GO:0019215,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019899,GO:0019900,GO:0019902,GO:0019903,GO:0020012,GO:0022610,GO:0023051,GO:0023056,GO:0023057,GO:0030162,GO:0030234,GO:0030260,GO:0030307,GO:0030430,GO:0030682,GO:0030683,GO:0030888,GO:0030889,GO:0031072,GO:0031090,GO:0031267,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031329,GO:0031330,GO:0031347,GO:0031348,GO:0031369,GO:0031399,GO:0031400,GO:0031401,GO:0031952,GO:0031953,GO:0032069,GO:0032074,GO:0032101,GO:0032102,GO:0032259,GO:0032268,GO:0032269,GO:0032270,GO:0032386,GO:0032465,GO:0032467,GO:0032675,GO:0032715,GO:0032774,GO:0032780,GO:0032879,GO:0032880,GO:0032944,GO:0032945,GO:0032991,GO:0032993,GO:0033036,GO:0033043,GO:0033116,GO:0033592,GO:0033643,GO:0033644,GO:0033645,GO:0033646,GO:0033647,GO:0033648,GO:0033650,GO:0033655,GO:0033662,GO:0033663,GO:0033668,GO:0033673,GO:0034062,GO:0034121,GO:0034122,GO:0034135,GO:0034136,GO:0034143,GO:0034144,GO:0034155,GO:0034156,GO:0034163,GO:0034164,GO:0034248,GO:0034250,GO:0034641,GO:0034654,GO:0035303,GO:0035306,GO:0035325,GO:0035663,GO:0035821,GO:0036260,GO:0036265,GO:0039502,GO:0039503,GO:0039506,GO:0039507,GO:0039513,GO:0039516,GO:0039526,GO:0039527,GO:0039547,GO:0039560,GO:0039580,GO:0039584,GO:0039612,GO:0039613,GO:0039644,GO:0039653,GO:0039656,GO:0039657,GO:0039713,GO:0039714,GO:0040008,GO:0042000,GO:0042025,GO:0042127,GO:0042287,GO:0042288,GO:0042325,GO:0042326,GO:0042327,GO:0042509,GO:0042532,GO:0042802,GO:0042886,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043085,GO:0043086,GO:0043122,GO:0043123,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043414,GO:0043462,GO:0043487,GO:0043489,GO:0043549,GO:0043656,GO:0043657,GO:0043900,GO:0043901,GO:0043902,GO:0043903,GO:0044003,GO:0044053,GO:0044068,GO:0044092,GO:0044093,GO:0044164,GO:0044165,GO:0044167,GO:0044177,GO:0044186,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044220,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044279,GO:0044359,GO:0044362,GO:0044403,GO:0044409,GO:0044413,GO:0044414,GO:0044415,GO:0044417,GO:0044419,GO:0044422,GO:0044424,GO:0044444,GO:0044464,GO:0044501,GO:0044531,GO:0044532,GO:0044766,GO:0044833,GO:0044877,GO:0045069,GO:0045070,GO:0045088,GO:0045184,GO:0045727,GO:0045787,GO:0045824,GO:0045862,GO:0045892,GO:0045927,GO:0045934,GO:0045936,GO:0045937,GO:0046425,GO:0046426,GO:0046483,GO:0046718,GO:0046755,GO:0046762,GO:0046774,GO:0046794,GO:0046872,GO:0046914,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048524,GO:0048583,GO:0048584,GO:0048585,GO:0050670,GO:0050672,GO:0050687,GO:0050688,GO:0050689,GO:0050690,GO:0050691,GO:0050708,GO:0050709,GO:0050727,GO:0050728,GO:0050730,GO:0050732,GO:0050776,GO:0050777,GO:0050789,GO:0050790,GO:0050792,GO:0050794,GO:0050864,GO:0050865,GO:0050866,GO:0050869,GO:0050896,GO:0051020,GO:0051046,GO:0051047,GO:0051048,GO:0051049,GO:0051050,GO:0051051,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051223,GO:0051224,GO:0051234,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051249,GO:0051250,GO:0051252,GO:0051253,GO:0051302,GO:0051336,GO:0051338,GO:0051345,GO:0051346,GO:0051348,GO:0051701,GO:0051704,GO:0051707,GO:0051726,GO:0051781,GO:0051805,GO:0051806,GO:0051807,GO:0051808,GO:0051817,GO:0051828,GO:0051832,GO:0051833,GO:0051834,GO:0051836,GO:0052026,GO:0052027,GO:0052029,GO:0052031,GO:0052037,GO:0052038,GO:0052040,GO:0052041,GO:0052053,GO:0052055,GO:0052056,GO:0052148,GO:0052150,GO:0052167,GO:0052170,GO:0052173,GO:0052199,GO:0052200,GO:0052203,GO:0052204,GO:0052205,GO:0052230,GO:0052248,GO:0052250,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052312,GO:0052433,GO:0052490,GO:0052493,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0060147,GO:0060149,GO:0060255,GO:0060338,GO:0060339,GO:0060341,GO:0060548,GO:0060589,GO:0060590,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0060759,GO:0060760,GO:0060761,GO:0060966,GO:0060967,GO:0060968,GO:0060969,GO:0065007,GO:0065008,GO:0065009,GO:0070011,GO:0070103,GO:0070104,GO:0070201,GO:0070486,GO:0070663,GO:0070664,GO:0071593,GO:0071702,GO:0071704,GO:0071705,GO:0072583,GO:0075109,GO:0075111,GO:0075112,GO:0075114,GO:0075136,GO:0075344,GO:0075509,GO:0075512,GO:0075528,GO:0080009,GO:0080090,GO:0080134,GO:0080135,GO:0090068,GO:0090087,GO:0090199,GO:0090201,GO:0090304,GO:0097159,GO:0097617,GO:0097659,GO:0097677,GO:0097747,GO:0098588,GO:0098609,GO:0098657,GO:0098772,GO:0106005,GO:0140096,GO:0140098,GO:1900101,GO:1900102,GO:1900117,GO:1900118,GO:1900368,GO:1900369,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901576,GO:1902369,GO:1902531,GO:1902532,GO:1902533,GO:1902579,GO:1902679,GO:1903265,GO:1903506,GO:1903507,GO:1903530,GO:1903531,GO:1903573,GO:1903719,GO:1903721,GO:1903900,GO:1903902,GO:1904892,GO:1904893,GO:1904950,GO:1905897,GO:1990214,GO:1990216,GO:1990219,GO:1990254,GO:1990814,GO:1990904,GO:2000112,GO:2000113,GO:2001141,GO:2001233,GO:2001234 - - - - - - - - - - - k59_100638_1 438753.AZC_3585 1.96e-72 233.0 28IR7@1|root,2Z8QR@2|Bacteria,1PBTP@1224|Proteobacteria,2U248@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_125165_1 1692242.A0A0K1RKZ2_9CIRC 1.73e-40 148.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_125165_2 1692256.A0A0K1RL85_9CIRC 2.55e-89 275.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_39461_2 1117943.SFHH103_00136 4.97e-25 105.0 2AIT3@1|root,319A1@2|Bacteria,1Q25I@1224|Proteobacteria,2V9MC@28211|Alphaproteobacteria,4BJY9@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_270450_3 1609634.A0A0C5AFT2_9VIRU 1.06e-107 323.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_161477_1 926561.KB900623_gene745 7.44e-28 118.0 COG1196@1|root,COG1196@2|Bacteria,1TQY7@1239|Firmicutes,248AP@186801|Clostridia 186801|Clostridia D nuclear chromosome segregation - - - - - - - - - - - - AAA_15,AAA_23,AAA_27,AAA_29,DUF2813 k59_126459_3 1165094.RINTHH_3920 1.01e-57 192.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_65649_7 1114959.SZMC14600_22475 6.22e-48 160.0 arCOG05626@1|root,30CNA@2|Bacteria,2I38B@201174|Actinobacteria,4EDYI@85010|Pseudonocardiales 201174|Actinobacteria - - - - - - - - - - - - - - - k59_101981_2 396014.BF93_12555 1.22e-05 50.8 COG1403@1|root,COG1403@2|Bacteria,2GMJV@201174|Actinobacteria,4FCIP@85020|Dermabacteraceae 201174|Actinobacteria L HNH endonuclease - - - - - - - - - - - - HNH,HNH_5 k59_53277_1 311424.DhcVS_1286 3.17e-12 70.9 2DBHG@1|root,2Z99H@2|Bacteria 2|Bacteria - - mom - - ko:K21527 - - - - ko00000,ko01000 - - - - k59_368851_5 665956.HMPREF1032_00650 9.93e-49 168.0 COG0553@1|root,COG0553@2|Bacteria,1TS9W@1239|Firmicutes,24CGX@186801|Clostridia,3WN6X@541000|Ruminococcaceae 186801|Clostridia KL Helicase conserved C-terminal domain - - - - - - - - - - - - - k59_4946_4 1046714.AMRX01000006_gene3163 1.51e-24 95.9 2D7I9@1|root,32TP3@2|Bacteria,1N2ZM@1224|Proteobacteria,1S9DB@1236|Gammaproteobacteria,46BK3@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1364) ybcO - - - - - - - - - - - DUF1364 k59_113686_1 1385658.U5KPZ6_9VIRU 1.04e-11 65.1 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_126466_1 1406780.U5PWH9_9CAUD 6.2e-18 87.4 4QBY0@10239|Viruses,4QW35@35237|dsDNA viruses no RNA stage,4QQ4Q@28883|Caudovirales,4QNNN@10744|Podoviridae 10744|Podoviridae S UvrD-like helicase C-terminal domain - - - - - - - - - - - - - k59_162780_1 629773.AORY01000012_gene1045 9.91e-68 228.0 COG4733@1|root,COG4733@2|Bacteria,1NSJG@1224|Proteobacteria,2UR1D@28211|Alphaproteobacteria,2KDBE@204457|Sphingomonadales 204457|Sphingomonadales S cellulase activity - - - - - - - - - - - - - k59_65669_1 1415780.JPOG01000001_gene1744 1.6e-12 73.6 COG0454@1|root,COG0827@1|root,COG1040@1|root,COG3087@1|root,COG0456@2|Bacteria,COG0827@2|Bacteria,COG1040@2|Bacteria,COG3087@2|Bacteria,1PI1K@1224|Proteobacteria,1T6BU@1236|Gammaproteobacteria,1XB7I@135614|Xanthomonadales 135614|Xanthomonadales D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - - - - - - - - - - - k59_4949_1 1220717.L7TL12_9VIRU 8.53e-45 165.0 4QCWX@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_356865_2 419665.Maeo_0388 1.6e-07 57.4 COG0399@1|root,arCOG00118@2157|Archaea,2XTRQ@28890|Euryarchaeota,23QJ1@183939|Methanococci 28890|Euryarchaeota E Belongs to the DegT DnrJ EryC1 family - - 1.17.1.1,2.6.1.102 ko:K12452,ko:K13010 ko00520,map00520 - R03391,R03392,R10460 RC00006,RC00230,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 - - - DegT_DnrJ_EryC1 k59_175018_6 1692252.A0A0K1RL35_9CIRC 3.89e-45 163.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_369925_1 1408419.JHYG01000005_gene718 1.6e-07 57.8 COG0582@1|root,COG0582@2|Bacteria,1N2H9@1224|Proteobacteria,2TS7K@28211|Alphaproteobacteria,2JRTQ@204441|Rhodospirillales 204441|Rhodospirillales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_int_SAM_1,Phage_integrase k59_297718_1 1788445.A0A190WHA3_9CIRC 3.27e-24 101.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_286989_2 1692244.A0A0K1RLR5_9CIRC 5.12e-43 149.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_286989_3 1692255.A0A0K1RL52_9CIRC 1.89e-25 104.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_225004_1 1165094.RINTHH_3920 3.31e-25 105.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_225004_3 1609634.A0A0C5AFV4_9VIRU 3.04e-125 377.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_200262_3 1206741.BAFX01000186_gene6740 4.33e-21 107.0 COG0791@1|root,COG5280@1|root,COG0791@2|Bacteria,COG5280@2|Bacteria,2I3FN@201174|Actinobacteria,4FXRG@85025|Nocardiaceae 201174|Actinobacteria M Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_139656_2 630626.EBL_c21830 2.23e-78 249.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,1RY0J@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_346235_2 1280688.AUJB01000011_gene2236 8.98e-07 53.9 COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,3NGI4@46205|Pseudobutyrivibrio 186801|Clostridia L zinc finger dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k59_236558_1 1220717.L7TND1_9VIRU 1e-12 80.1 4QAK6@10239|Viruses 10239|Viruses S N-acetylmuramoyl-L-alanine amidase activity - GO:0005575,GO:0018995,GO:0019012,GO:0030430,GO:0033643,GO:0033646,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_78935_4 1214065.BAGV01000099_gene2075 9.42e-50 166.0 COG1475@1|root,COG1475@2|Bacteria,1R5VN@1224|Proteobacteria,1RZ7C@1236|Gammaproteobacteria 1236|Gammaproteobacteria K ParB-like nuclease domain ybdM - - - - - - - - - - - ParBc k59_358085_1 399795.CtesDRAFT_PD2911 2.59e-11 72.8 COG2304@1|root,COG3209@1|root,COG4733@1|root,COG2304@2|Bacteria,COG3209@2|Bacteria,COG4733@2|Bacteria,1MXB4@1224|Proteobacteria,2VJS7@28216|Betaproteobacteria,4AHBA@80864|Comamonadaceae 28216|Betaproteobacteria M Putative phage tail protein - - - - - - - - - - - - Phage-tail_3 k59_348076_1 675815.VOA_001658 2.93e-14 83.2 COG5362@1|root,COG5362@2|Bacteria,1N1KT@1224|Proteobacteria,1RRC7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S TIGRFAM Phage - - - - - - - - - - - - - k59_141369_1 646529.Desaci_1311 2.47e-23 106.0 COG5280@1|root,COG5280@2|Bacteria,1UHTF@1239|Firmicutes,25ECD@186801|Clostridia 186801|Clostridia M Tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail k59_336089_1 1123279.ATUS01000001_gene2720 4.42e-57 190.0 COG4128@1|root,COG4128@2|Bacteria,1RCY8@1224|Proteobacteria,1S4JQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_238205_2 1692253.A0A0K1RLM4_9CIRC 1.18e-26 114.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_348079_1 861530.ALOZ01000059_gene122 1.02e-12 80.5 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,4GXIN@90964|Staphylococcaceae 91061|Bacilli L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A k59_68720_2 1234888.K0A2J2_9VIRU 5.57e-42 152.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_178293_1 1221537.B807_216 1.22e-22 102.0 COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,4HAG5@91061|Bacilli,3F3KU@33958|Lactobacillaceae 91061|Bacilli L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA - - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA k59_383809_1 1370121.AUWS01000008_gene5592 1.04e-10 73.9 COG0791@1|root,COG1388@1|root,COG5412@1|root,COG0791@2|Bacteria,COG1388@2|Bacteria,COG5412@2|Bacteria,2GNNQ@201174|Actinobacteria,23809@1762|Mycobacteriaceae 201174|Actinobacteria M phage tail tape measure protein - - - - - - - - - - - - PhageMin_Tail,SLT k59_33959_3 593117.TGAM_0130 7.32e-40 146.0 COG0468@1|root,arCOG00415@2157|Archaea,2XT80@28890|Euryarchaeota,242UY@183968|Thermococci 183968|Thermococci L Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules radA GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - ko:K04483 - - - - ko00000,ko03400 - - - HHH_5,Intein_splicing,LAGLIDADG_3,Rad51 k59_228666_1 1463856.JOHY01000005_gene2033 2e-13 65.5 2C3CA@1|root,2ZUNU@2|Bacteria,2GZBJ@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_263961_1 1477404.A0A023NH97_9CAUD 1.26e-146 449.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNBK@10744|Podoviridae 10744|Podoviridae S Ribonucleotide reductase, barrel domain - - - - - - - - - - - - - k59_180002_1 414684.RC1_1106 0.00017 43.1 COG3926@1|root,COG3926@2|Bacteria,1MVXW@1224|Proteobacteria,2TT3H@28211|Alphaproteobacteria,2JXDU@204441|Rhodospirillales 204441|Rhodospirillales S Glycosyl hydrolase 108 - - - - - - - - - - - - Glyco_hydro_108,PG_binding_3 k59_313129_1 1618260.A0A0C5I2C5_9CIRC 1.21e-19 86.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_216840_1 573174.M4M9T1_9VIRU 3.64e-71 227.0 4QAR1@10239|Viruses,4QUNA@35237|dsDNA viruses no RNA stage 10239|Viruses S ATPase activity - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039686,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_385323_2 348824.LPU83_0595 4.13e-32 126.0 COG3740@1|root,COG3740@2|Bacteria,1QVIJ@1224|Proteobacteria,2TVIM@28211|Alphaproteobacteria,4BNVZ@82115|Rhizobiaceae 28211|Alphaproteobacteria S Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_228671_1 1476391.X5KNB4_9CAUD 2.3e-59 221.0 4QAXA@10239|Viruses,4QYJI@35237|dsDNA viruses no RNA stage,4QQ1A@28883|Caudovirales,4QNU7@10744|Podoviridae 10744|Podoviridae S metallopeptidase activity - - - - - - - - - - - - - k59_360960_2 469610.HMPREF0189_01104 3.6e-05 46.6 COG1783@1|root,COG5323@1|root,COG1783@2|Bacteria,COG5323@2|Bacteria 2|Bacteria M Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_252349_5 1187851.A33M_1701 1.25e-45 181.0 COG1345@1|root,COG1511@1|root,COG1345@2|Bacteria,COG1511@2|Bacteria,1QW8I@1224|Proteobacteria,2TU4X@28211|Alphaproteobacteria 28211|Alphaproteobacteria N Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end - - - - - - - - - - - - TMP_2 k59_167211_3 1562701.BBOF01000081_gene253 3.58e-77 248.0 28NGF@1|root,2Z9HT@2|Bacteria,1R9QF@1224|Proteobacteria,2VPSU@28216|Betaproteobacteria,1KD23@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_203913_1 1069080.KB913028_gene1828 1.75e-86 266.0 COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,4H1YW@909932|Negativicutes 909932|Negativicutes L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N k59_385475_1 1379717.S5SY19_9CIRC 1.44e-54 186.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_218557_2 682795.AciX8_1851 6.99e-11 68.9 COG3772@1|root,COG3772@2|Bacteria,3Y8CN@57723|Acidobacteria,2JNC8@204432|Acidobacteriia 204432|Acidobacteriia S Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_362440_1 1385658.U5KPZ6_9VIRU 1.28e-22 104.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_253938_1 1540098.A0A0A0RQI2_9CAUD 8.64e-33 134.0 4QB5I@10239|Viruses,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_21831_5 145579.B_BPPHM 6.71e-22 93.2 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_230480_1 764299.STRIC_2110 1.09e-32 138.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,4H9Z7@91061|Bacilli 91061|Bacilli L DNA polymerase polA_2 - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_327478_1 1445613.JALM01000071_gene6643 3.81e-23 98.6 COG1398@1|root,COG1398@2|Bacteria,2GJJF@201174|Actinobacteria,4E1KH@85010|Pseudonocardiales 201174|Actinobacteria I PFAM Fatty acid desaturase - - 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 - R02222 RC00917 ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase k59_362609_2 490913.C4NTD0_9CAUD 6.85e-19 85.1 4QBY0@10239|Viruses,4QW35@35237|dsDNA viruses no RNA stage,4QQ4Q@28883|Caudovirales,4QNNN@10744|Podoviridae 10744|Podoviridae S UvrD-like helicase C-terminal domain - - - - - - - - - - - - - k59_10551_1 1618259.A0A0C5I2B5_9CIRC 2.21e-07 57.0 4QE84@10239|Viruses,4QUKR@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_144889_2 942016.E9NIF8_9CAUD 4.43e-62 204.0 4QAR1@10239|Viruses,4QUNA@35237|dsDNA viruses no RNA stage,4QPJE@28883|Caudovirales,4QNDS@10744|Podoviridae 10744|Podoviridae S ATPase activity - - - - - - - - - - - - - k59_189753_1 1618247.A0A0C5IMK7_9CIRC 0.000932 47.4 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_218699_5 1505227.A0A076GAF9_9CAUD 1.48e-52 167.0 4QGQX@10239|Viruses,4QQ2D@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_24210_1 1609634.A0A0C5ANA6_9VIRU 2.18e-16 77.8 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_24210_2 1609634.A0A0C5AFV4_9VIRU 4.18e-227 643.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_388402_2 1618238.A0A0C5IB41_9CIRC 3.05e-10 68.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388405_1 1234888.K0A2J2_9VIRU 1.29e-50 176.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_388405_5 888743.HMPREF9141_0984 2.89e-08 63.2 2EVUA@1|root,33P81@2|Bacteria,4P82D@976|Bacteroidetes,2FV68@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_388405_7 1234888.K0A2J2_9VIRU 1.52e-98 306.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_191781_1 1165094.RINTHH_3920 6.6e-22 97.1 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_388409_1 1611039.A0A0C5C3Z3_9CIRC 4.78e-28 114.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388409_2 1618248.A0A0C5IB82_9CIRC 2.44e-25 105.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388415_1 1692249.A0A0K1RLN8_9CIRC 2.04e-30 117.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_388416_1 1788444.A0A190WHB9_9CIRC 3.34e-30 118.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_388624_1 1618248.A0A0C5IB82_9CIRC 1.05e-87 271.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_341450_3 1121448.DGI_2053 1.68e-97 299.0 COG4653@1|root,COG4653@2|Bacteria,1MXMN@1224|Proteobacteria,42UKA@68525|delta/epsilon subdivisions,2WQZV@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_365713_1 348824.LPU83_0595 1.32e-37 143.0 COG3740@1|root,COG3740@2|Bacteria,1QVIJ@1224|Proteobacteria,2TVIM@28211|Alphaproteobacteria,4BNVZ@82115|Rhizobiaceae 28211|Alphaproteobacteria S Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_244213_3 948071.S4S2D9_9CAUD 1.01e-255 724.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae 10744|Podoviridae S ribonucleoside-triphosphate reductase activity - - - - - - - - - - - - - k59_244213_5 194699.Q774Z7_BPBPP 1.77e-19 82.0 4QAZF@10239|Viruses,4QUTY@35237|dsDNA viruses no RNA stage,4QPH6@28883|Caudovirales,4QNEM@10744|Podoviridae 10744|Podoviridae S Protein of unknwon function (DUF3310) - - - - - - - - - - - - - k59_171631_7 32057.KB217478_gene2672 1.85e-36 129.0 COG5113@1|root,COG3236@2|Bacteria 2|Bacteria O hydrolase activity, hydrolyzing N-glycosyl compounds - - - ko:K09935 - - - - ko00000 - - - DUF1768 k59_74555_1 1005994.GTGU_01420 1.82e-05 54.7 28HCK@1|root,2Z7PE@2|Bacteria,1NK7S@1224|Proteobacteria,1S03Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_256699_1 1449126.JQKL01000002_gene1685 2.43e-28 118.0 COG3170@1|root,COG3170@2|Bacteria,1UMRZ@1239|Firmicutes,24SRA@186801|Clostridia 186801|Clostridia NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - k59_50226_2 279303.Q6J817_9CAUD 1.84e-29 121.0 4QG9U@10239|Viruses,4R0A6@35237|dsDNA viruses no RNA stage,4QSKC@28883|Caudovirales,4QM4R@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_317650_1 1379715.S5TMW6_9CIRC 1.12e-51 176.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_62530_2 1795988.A0A140CTK3_9VIRU 2.33e-26 114.0 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_135052_1 742740.HMPREF9474_02273 3.51e-05 47.4 2EAAT@1|root,334F2@2|Bacteria,1VJJI@1239|Firmicutes,24TQU@186801|Clostridia,223KD@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_135052_2 691965.D4P7C3_9CAUD 2.48e-31 114.0 4QDCX@10239|Viruses,4R0GS@35237|dsDNA viruses no RNA stage,4QS3P@28883|Caudovirales,4QKU8@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_135052_3 742733.HMPREF9469_05036 3.13e-53 171.0 2AIHK@1|root,318ZG@2|Bacteria,1V7P0@1239|Firmicutes,24KNU@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_135052_5 691965.D4P7B9_9CAUD 2.58e-29 108.0 4QFDH@10239|Viruses,4QWV5@35237|dsDNA viruses no RNA stage,4QPB8@28883|Caudovirales,4QKNN@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_135052_6 935848.JAEN01000011_gene1848 1.98e-07 58.9 COG3409@1|root,COG3409@2|Bacteria,1RAYU@1224|Proteobacteria,2U6D1@28211|Alphaproteobacteria,2PXU7@265|Paracoccus 28211|Alphaproteobacteria M N-acetylmuramidase - - - - - - - - - - - - Muraidase,PG_binding_1 k59_305437_1 292414.TM1040_1655 3.65e-12 71.2 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - ko:K12287 - - - - ko00000,ko02044 - - - DUF11,VCBS k59_38722_1 621372.ACIH01000214_gene1012 3.88e-09 64.3 2BUJY@1|root,32PWF@2|Bacteria,1VP06@1239|Firmicutes,4I0WX@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k59_38722_3 1150621.SMUL_1732 1.48e-13 75.9 29X4D@1|root,30IT8@2|Bacteria,1Q30S@1224|Proteobacteria,42WJT@68525|delta/epsilon subdivisions,2YQ6Y@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S Domain of unknown function (DUF4373) - - - - - - - - - - - - DUF4373 k59_38722_4 279808.SH1757 0.00011 48.1 COG3440@1|root,COG3440@2|Bacteria,1V6VD@1239|Firmicutes,4HUXV@91061|Bacilli 91061|Bacilli V Restriction endonuclease - - - - - - - - - - - - DUF2726 k59_221661_1 579138.Zymop_0823 1.42e-179 513.0 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,2TV42@28211|Alphaproteobacteria,2K7D4@204457|Sphingomonadales 204457|Sphingomonadales S TIGRFAM phage terminase, large subunit, PBSX family - - - ko:K06909 - - - - ko00000 - - - Terminase_3 k59_111871_3 322855.Q52PN4_9CAUD 5.3e-81 270.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales 28883|Caudovirales S N-methyltransferase activity - - - - - - - - - - - - - k59_26919_1 1117943.SFHH103_00150 1.85e-28 116.0 2DPZ1@1|root,3340X@2|Bacteria,1R2EE@1224|Proteobacteria,2TZIB@28211|Alphaproteobacteria,4BP2Q@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_136233_2 1379695.S5SXZ1_9CIRC 1.49e-20 102.0 4QD5V@10239|Viruses 10239|Viruses S Viral coat protein (S domain) - GO:0003674,GO:0003676,GO:0003723,GO:0005198,GO:0005488,GO:0005509,GO:0005575,GO:0008289,GO:0019012,GO:0019028,GO:0019030,GO:0039617,GO:0039660,GO:0043167,GO:0043169,GO:0044423,GO:0046872,GO:0097159,GO:1901363 - - - - - - - - - - - k59_124431_5 585.DR95_1301 4.26e-36 127.0 COG3108@1|root,COG3108@2|Bacteria,1RICX@1224|Proteobacteria,1S6D5@1236|Gammaproteobacteria 1236|Gammaproteobacteria S peptidase M15 - - - ko:K17733 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M15_4 k59_342706_1 1122132.AQYH01000015_gene2270 4.52e-37 149.0 COG3170@1|root,COG3170@2|Bacteria,1QVEE@1224|Proteobacteria,2TWDG@28211|Alphaproteobacteria,4BHSG@82115|Rhizobiaceae 28211|Alphaproteobacteria NU Phage P22-like portal protein - - - - - - - - - - - - P22_portal k59_136356_4 475178.B2BTN9_9CAUD 1.52e-10 64.7 4QB9J@10239|Viruses,4QXFE@35237|dsDNA viruses no RNA stage,4QS1Z@28883|Caudovirales,4QN8F@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_269885_1 1234888.K0A2J2_9VIRU 1.34e-70 229.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_355177_2 1556290.A0A0A0RL61_9CAUD 1.72e-86 271.0 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - GO:0005575,GO:0019012,GO:0019028,GO:0032991,GO:0044423,GO:0046806 - - - - - - - - - - - k59_294393_1 1692249.A0A0K1RLN8_9CIRC 1.94e-25 107.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_149614_2 1071073.KI530537_gene2289 5.09e-30 117.0 COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4HB7M@91061|Bacilli,1ZB7H@1386|Bacillus 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII k59_356198_1 1385658.U5KPZ6_9VIRU 2.96e-75 245.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_113068_1 1100720.ALKN01000018_gene1726 8.8e-127 382.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2VNHP@28216|Betaproteobacteria,4AC68@80864|Comamonadaceae 28216|Betaproteobacteria S Terminase - - - - - - - - - - - - Terminase_1 k59_113068_2 1469948.JPNB01000001_gene691 6.83e-28 114.0 COG4695@1|root,COG4695@2|Bacteria,1TP8B@1239|Firmicutes,2497C@186801|Clostridia,36H1A@31979|Clostridiaceae 186801|Clostridia S Phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_343994_1 476272.RUMHYD_01785 5.95e-22 100.0 COG1511@1|root,COG3941@1|root,COG5412@1|root,COG1511@2|Bacteria,COG3941@2|Bacteria,COG5412@2|Bacteria,1TQDE@1239|Firmicutes,249I0@186801|Clostridia,3Y0ZQ@572511|Blautia 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_28207_1 1234888.K0A2J2_9VIRU 6.33e-59 200.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_210911_1 1463854.JOHT01000033_gene2588 2.21e-09 63.9 COG0863@1|root,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - 2.1.1.72 ko:K00571,ko:K07319 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_344002_2 1219035.NT2_13_00580 1.43e-25 106.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_125808_9 500632.CLONEX_02252 6.88e-50 171.0 COG0270@1|root,COG0270@2|Bacteria,1TS3G@1239|Firmicutes,249Q9@186801|Clostridia 186801|Clostridia H Psort location Cytoplasmic, score - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_320232_3 156889.Mmc1_1558 5.55e-37 137.0 COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,2TRJX@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Belongs to the KdsA family kdsA - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 k59_223086_2 645099.MREP_BBTVA 7.92e-13 75.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_356380_1 1609634.A0A0C5AFT2_9VIRU 1.86e-78 246.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_125816_1 32057.KB217478_gene2057 8.64e-29 111.0 2DR0J@1|root,32UQ6@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_53983_1 1618236.A0A0C5IB23_9CIRC 8.58e-32 130.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_175824_1 665956.HMPREF1032_00674 0.000842 45.8 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia,3WNJZ@541000|Ruminococcaceae 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_102784_1 1219035.NT2_15_00110 2.37e-14 74.7 2CFWB@1|root,2Z8W6@2|Bacteria,1PRU1@1224|Proteobacteria,2TUGM@28211|Alphaproteobacteria,2K8GY@204457|Sphingomonadales 204457|Sphingomonadales S Antitoxin of toxin-antitoxin stability system - - - - - - - - - - - - - k59_286538_2 488538.SAR116_0382 4.94e-15 82.0 28S81@1|root,2ZEJD@2|Bacteria,1RCNN@1224|Proteobacteria,2U6Z0@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_260306_1 999549.KI421514_gene429 6.2e-11 65.9 COG1961@1|root,COG1961@2|Bacteria,1MXXT@1224|Proteobacteria,2U9WZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Site-specific recombinases, DNA invertase Pin homologs tnpR - - ko:K14060 - - - - ko00000 - - - HTH_7,Resolvase k59_357579_1 1121377.KB906398_gene1999 8.86e-50 186.0 COG0507@1|root,COG0507@2|Bacteria 2|Bacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - - - - - - - - - - AAA_30,HTH_31,N_BRCA1_IG k59_102788_2 2003327.CAPSD_BPCHP 1.52e-52 191.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_286547_2 999611.KI421504_gene3031 2.94e-60 189.0 2E04N@1|root,32VT5@2|Bacteria,1N310@1224|Proteobacteria,2URAT@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_78393_3 1385658.U5KPZ6_9VIRU 5.31e-201 577.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_78393_4 105154.Q9MBU3_9VIRU 1.01e-10 62.4 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_272946_1 49964.Q94MS1_9CAUD 3.23e-72 228.0 4QB4H@10239|Viruses,4QYQI@35237|dsDNA viruses no RNA stage,4QUAR@28883|Caudovirales,4QNUV@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_151478_2 767029.HMPREF9154_3098 1.9e-31 127.0 COG0791@1|root,COG3409@1|root,COG0791@2|Bacteria,COG3409@2|Bacteria,2IK6V@201174|Actinobacteria 201174|Actinobacteria M NLP P60 protein - - - - - - - - - - - - CHAP,NLPC_P60 k59_383294_1 1609634.A0A0C5AFV4_9VIRU 1.02e-184 533.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_383294_4 1609634.A0A0C5AFT2_9VIRU 1.88e-105 317.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_177659_1 35754.JNYJ01000012_gene914 1.77e-30 115.0 COG0638@1|root,COG0638@2|Bacteria,2IHBU@201174|Actinobacteria,4DH8W@85008|Micromonosporales 201174|Actinobacteria O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine - - - - - - - - - - - - - k59_153270_1 226185.EF_0330 7.01e-36 137.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H9YP@91061|Bacilli,4B1S9@81852|Enterococcaceae 91061|Bacilli KL SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_226480_3 1609634.A0A0C5AFV4_9VIRU 1.63e-120 363.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_311058_2 202956.BBNL01000011_gene2402 3.37e-56 191.0 2CHRY@1|root,30Z9E@2|Bacteria,1RGQK@1224|Proteobacteria,1T1AM@1236|Gammaproteobacteria,3NKV5@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - RecT k59_311058_4 911008.GLAD_00750 1.23e-16 80.9 COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,1RPSH@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase,Dam,MethyltransfD12 k59_165334_1 1536772.R70723_27470 8.56e-12 65.9 COG0457@1|root,COG0463@1|root,COG0457@2|Bacteria,COG0463@2|Bacteria,1TRCN@1239|Firmicutes,4I294@91061|Bacilli,26U0U@186822|Paenibacillaceae 91061|Bacilli M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2,TPR_16,TPR_7,TPR_8 k59_43680_1 105154.Q9MBU0_9VIRU 1.26e-38 144.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_129187_1 1248916.ANFY01000003_gene847 9.46e-31 116.0 COG3409@1|root,COG3409@2|Bacteria,1REI1@1224|Proteobacteria,2U734@28211|Alphaproteobacteria,2K4CS@204457|Sphingomonadales 204457|Sphingomonadales M Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_1 k59_141039_1 187764.Q8SCG7_9CAUD 1.53e-13 76.6 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_94908_1 1788445.A0A190WHA3_9CIRC 3.82e-22 94.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_276213_1 225937.HP15_3095 2.45e-32 124.0 COG4128@1|root,COG4128@2|Bacteria,1N0I7@1224|Proteobacteria,1SAH8@1236|Gammaproteobacteria,46BMP@72275|Alteromonadaceae 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) zot GO:0001906,GO:0006810,GO:0006996,GO:0007010,GO:0008150,GO:0009405,GO:0009987,GO:0016043,GO:0031640,GO:0035821,GO:0042044,GO:0042045,GO:0044364,GO:0044419,GO:0051179,GO:0051234,GO:0051704,GO:0070633,GO:0071840 - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_166768_1 1219049.SP5_030_00160 1.24e-11 70.9 COG4227@1|root,COG4227@2|Bacteria,1MU8I@1224|Proteobacteria,2TRIT@28211|Alphaproteobacteria,2K1FU@204457|Sphingomonadales 204457|Sphingomonadales L Domain of unknown function (DUF1738) - - - - - - - - - - - - DUF1738 k59_373132_3 1123060.JONP01000017_gene5390 5.34e-37 136.0 2CWYZ@1|root,32T0P@2|Bacteria,1MZEM@1224|Proteobacteria,2UCCZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_45382_1 1082932.ATCR1_06771 9.42e-104 310.0 28NGF@1|root,2ZBII@2|Bacteria,1R9KY@1224|Proteobacteria,2U1P7@28211|Alphaproteobacteria,4B747@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_360731_1 1336243.JAEA01000002_gene2660 5.69e-53 190.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT52@1224|Proteobacteria,2TVNI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_2 k59_33681_1 595537.Varpa_1991 3.97e-09 62.8 COG0863@1|root,COG0863@2|Bacteria,1MY4G@1224|Proteobacteria,2VQD7@28216|Betaproteobacteria 28216|Betaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_337574_1 716928.AJQT01000109_gene1197 1.09e-13 73.6 2AM58@1|root,31BZI@2|Bacteria,1P06W@1224|Proteobacteria,2UU8Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_8886_1 1484479.DI14_04720 1.67e-19 95.1 COG5280@1|root,COG5283@1|root,COG5412@1|root,COG5280@2|Bacteria,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HAFE@91061|Bacilli,3WF4W@539002|Bacillales incertae sedis 91061|Bacilli S Phage tail tape measure protein - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,SLT k59_228314_1 1692259.A0A0K1RL59_9CIRC 0.000344 45.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_360901_2 1692262.A0A0K1RL89_9CIRC 3.6e-18 88.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_59279_1 742740.HMPREF9474_02303 2.56e-66 228.0 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia,221YV@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_71671_1 658401.C7F4B8_9CAUD 0.000115 53.5 4QH5W@10239|Viruses,4QYFG@35237|dsDNA viruses no RNA stage,4QQD8@28883|Caudovirales,4QN2T@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_265283_1 411460.RUMTOR_01335 2.45e-81 288.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_374842_2 1042375.AFPL01000026_gene3607 2.01e-30 124.0 COG5283@1|root,COG5283@2|Bacteria,1QZAD@1224|Proteobacteria,1RYP3@1236|Gammaproteobacteria 1236|Gammaproteobacteria D nuclear chromosome segregation - - - - - - - - - - - - - k59_59282_1 596323.HMPREF0554_0847 4.35e-20 85.5 2FCPU@1|root,344T2@2|Bacteria,37CG7@32066|Fusobacteria 32066|Fusobacteria - - - - - - - - - - - - - - - k59_314795_2 648757.Rvan_3315 3.55e-26 109.0 COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,3N62D@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_3,Terminase_6,Terminase_6C k59_168584_1 1234888.K0A2J2_9VIRU 5.18e-54 186.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_375048_1 1788438.A0A190WHE1_9CIRC 8.45e-12 72.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_47420_2 883067.HMPREF9237_00672 5.29e-05 47.4 COG2197@1|root,COG2197@2|Bacteria 2|Bacteria K response regulator - - - - - - - - - - - - GerE,Phosphonate-bd k59_253846_1 1288083.AUKR01000017_gene2523 7.88e-23 98.6 COG3409@1|root,COG3409@2|Bacteria 2|Bacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - Amidase_2,PG_binding_1 k59_314803_2 291603.MREP_FBNY1 3.1e-14 77.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_157251_2 633.DJ40_1485 2.6e-15 84.3 29F24@1|root,301ZW@2|Bacteria,1RDF7@1224|Proteobacteria,1S5EJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Head binding - - - - - - - - - - - - Head_binding k59_388441_1 1379709.S5TMV0_9CIRC 3.49e-13 71.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388441_3 1234880.K0A2H8_9CIRC 1.01e-24 105.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388451_1 145579.CAPSD_BPPHM 3e-51 182.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_388451_3 145579.REP_BPPHM 9.41e-34 131.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_388451_6 1385658.U5KPZ6_9VIRU 2.77e-93 293.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_388452_1 1692249.A0A0K1RL40_9CIRC 1.62e-07 56.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388457_1 1788439.A0A190WHD0_9CIRC 2.16e-26 110.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388457_7 291607.MREP_SCSVF 2.91e-06 49.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388462_1 1618241.A0A0C5I2I4_9CIRC 8.73e-93 284.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388462_2 1618236.A0A0C5I2F3_9CIRC 2.9e-48 172.0 4QGVY@10239|Viruses,4QUKN@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_192199_1 1234888.K0A2J2_9VIRU 6.4e-58 196.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_192199_7 1234888.K0A2J2_9VIRU 1.29e-38 142.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_73170_1 1692244.A0A0K1RLR5_9CIRC 1.05e-13 77.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_292176_1 1618254.A0A0C5IBG4_9CIRC 2.73e-21 91.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_24803_16 691965.D4P7I3_9CAUD 0.0 1362.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_195075_2 1026955.F5B4A4_9CAUD 1.01e-53 175.0 4QCXM@10239|Viruses,4QZZ5@35237|dsDNA viruses no RNA stage,4QT8U@28883|Caudovirales,4QJ27@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_61531_1 1322246.BN4_12396 3.06e-63 208.0 COG5323@1|root,COG5323@2|Bacteria,1R049@1224|Proteobacteria,42UYF@68525|delta/epsilon subdivisions,2WQN3@28221|Deltaproteobacteria,2M90K@213115|Desulfovibrionales 28221|Deltaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6 k59_328762_1 99179.B5TR86_9CAUD 1.79e-05 47.0 4QBK0@10239|Viruses,4QUSV@35237|dsDNA viruses no RNA stage,4QU9J@28883|Caudovirales,4QMQ0@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_24910_5 1609634.A0A0C5AFV4_9VIRU 2.08e-68 234.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_61539_2 1262532.R9R4J4_9CAUD 1.22e-60 194.0 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QPEB@28883|Caudovirales 28883|Caudovirales S phosphoprotein phosphatase activity - - - - - - - - - - - - - k59_304429_2 1120966.AUBU01000001_gene1209 0.000932 44.3 COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,47KP4@768503|Cytophagia 976|Bacteroidetes C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) pdhC - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k59_304429_9 720555.BATR1942_09815 6.8e-07 51.2 2EF0S@1|root,338TW@2|Bacteria,1VHGU@1239|Firmicutes,4HRI3@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k59_304429_11 649639.Bcell_2106 4.23e-37 158.0 COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HAFE@91061|Bacilli,1ZS5N@1386|Bacillus 91061|Bacilli D Phage tail tape measure protein - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,SLT k59_195999_1 942016.E9NIF8_9CAUD 1.93e-18 88.6 4QAR1@10239|Viruses,4QUNA@35237|dsDNA viruses no RNA stage,4QPJE@28883|Caudovirales,4QNDS@10744|Podoviridae 10744|Podoviridae S ATPase activity - - - - - - - - - - - - - k59_50233_13 691965.D4P7I3_9CAUD 0.0 1240.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_50233_14 742733.HMPREF9469_05065 2.21e-37 133.0 2E0G5@1|root,324TP@2|Bacteria,1UQZN@1239|Firmicutes,258ST@186801|Clostridia,222Q1@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_50233_15 742733.HMPREF9469_05062 1.65e-128 382.0 COG0553@1|root,COG0553@2|Bacteria,1TS9W@1239|Firmicutes,24CGX@186801|Clostridia,222GT@1506553|Lachnoclostridium 186801|Clostridia KL Helicase conserved C-terminal domain - - - - - - - - - - - - - k59_50233_17 478749.BRYFOR_08535 9.98e-52 171.0 29YRZ@1|root,30KMY@2|Bacteria,1V4Y4@1239|Firmicutes,24HPY@186801|Clostridia 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - DUF2800 k59_50233_18 691965.D4P7L7_9CAUD 1.67e-193 575.0 4QB9J@10239|Viruses,4QXFE@35237|dsDNA viruses no RNA stage,4QS1Z@28883|Caudovirales,4QN8F@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_268894_1 642492.Clole_0800 1.16e-07 54.3 COG4570@1|root,COG4570@2|Bacteria,1VF2H@1239|Firmicutes,24P18@186801|Clostridia 186801|Clostridia L Endodeoxyribonuclease RusA rusA - - - - - - - - - - - RusA k59_378244_2 1122138.AQUZ01000004_gene991 1.33e-22 95.9 COG3772@1|root,COG3772@2|Bacteria,2I4U1@201174|Actinobacteria 201174|Actinobacteria V hydrolase, family 25 - - - - - - - - - - - - - k59_305506_1 1165094.RINTHH_3920 3.47e-48 168.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_305506_3 105154.Q9MBU6_9VIRU 1.27e-227 646.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_220587_1 551789.ATVJ01000001_gene1805 4.63e-22 105.0 COG1573@1|root,COG1573@2|Bacteria,1MW8T@1224|Proteobacteria,2TSAR@28211|Alphaproteobacteria,43XC4@69657|Hyphomonadaceae 28211|Alphaproteobacteria L Domain of unknown function (DUF4130 - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - DUF4130,UDG k59_220587_4 907348.TresaDRAFT_0826 2.89e-06 57.8 COG1475@1|root,COG1475@2|Bacteria,2J5S6@203691|Spirochaetes 203691|Spirochaetes K Belongs to the ParB family spo0J - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_354182_2 1692252.A0A0K1RL35_9CIRC 4.27e-31 118.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_50239_2 1379717.S5SY19_9CIRC 3.07e-11 70.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_110966_1 929562.Emtol_1027 6.14e-07 59.3 COG1044@1|root,COG5295@1|root,COG1044@2|Bacteria,COG5295@2|Bacteria,4NKG1@976|Bacteroidetes,47NK6@768503|Cytophagia 976|Bacteroidetes MUW domain, Protein - - - - - - - - - - - - Peptidase_S74 k59_38081_2 663610.JQKO01000006_gene2685 6.33e-25 111.0 2EBXN@1|root,335X0@2|Bacteria,1RCC3@1224|Proteobacteria,2U2ZA@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_136272_2 1042375.AFPL01000042_gene3813 4.68e-39 133.0 2AD08@1|root,312N7@2|Bacteria,1NDC4@1224|Proteobacteria,1SAPT@1236|Gammaproteobacteria,467W0@72275|Alteromonadaceae 1236|Gammaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_233525_1 1403819.BATR01000046_gene1341 2.12e-34 129.0 COG0616@1|root,COG0616@2|Bacteria 2|Bacteria OU serine-type peptidase activity sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 k59_257759_1 240016.ABIZ01000001_gene1613 3.94e-42 157.0 COG0270@1|root,COG0270@2|Bacteria 2|Bacteria L DNA (cytosine-5-)-methyltransferase activity dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_63719_1 1191299.AJYX01000097_gene1585 4.83e-06 57.4 COG3325@1|root,COG3979@1|root,COG3325@2|Bacteria,COG3979@2|Bacteria,1MWAR@1224|Proteobacteria,1RPNS@1236|Gammaproteobacteria,1XT0T@135623|Vibrionales 135623|Vibrionales G COG3325 Chitinase chiA - 3.2.1.14 ko:K01183 ko00520,ko01100,map00520,map01100 - R01206,R02334 RC00467 ko00000,ko00001,ko01000 - GH18 - CBM_5_12,ChitinaseA_N,Glyco_hydro_18,REJ k59_63719_3 138119.DSY3134 0.000198 53.9 COG2247@1|root,COG4932@1|root,COG2247@2|Bacteria,COG4932@2|Bacteria,1V5FN@1239|Firmicutes 1239|Firmicutes M Cell wall-binding - - - - - - - - - - - - Big_1,CW_binding_2,CarboxypepD_reg k59_355054_2 877455.Metbo_2475 4.23e-29 135.0 COG3291@1|root,arCOG02516@1|root,arCOG09475@1|root,arCOG02508@2157|Archaea,arCOG02510@2157|Archaea,arCOG02516@2157|Archaea,arCOG09475@2157|Archaea,2Y7U0@28890|Euryarchaeota 28890|Euryarchaeota S Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - - - - - - - - - - PKD k59_136279_2 314262.MED193_12573 1.94e-17 79.7 28NSJ@1|root,2ZBRH@2|Bacteria,1RAXM@1224|Proteobacteria,2U60W@28211|Alphaproteobacteria,2P4CP@2433|Roseobacter 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_124492_1 1618237.A0A0C5IMG6_9CIRC 5.91e-12 72.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_148266_3 1122201.AUAZ01000017_gene2950 8.02e-32 125.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,1RY1X@1236|Gammaproteobacteria,46BED@72275|Alteromonadaceae 1236|Gammaproteobacteria S associated with various cellular activities - - - - - - - - - - - - AAA,AAA_5 k59_75651_3 673376.F2VHW2_9CAUD 1.66e-26 99.8 4QCCA@10239|Viruses,4QY28@35237|dsDNA viruses no RNA stage,4QU0Q@28883|Caudovirales,4QNA0@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_245569_1 1234888.K0A2J2_9VIRU 4.48e-87 275.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_355185_1 1231190.NA8A_04863 8.89e-10 68.9 2FEZT@1|root,346YB@2|Bacteria,1RB9X@1224|Proteobacteria,2U5I3@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - Collagen k59_331238_1 1986029.Q9MBM8_9VIRU 1.54e-30 121.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_87909_1 1082933.MEA186_01041 1.06e-26 115.0 2CDQ7@1|root,2Z7KV@2|Bacteria,1MY2D@1224|Proteobacteria,2TR92@28211|Alphaproteobacteria,43J4F@69277|Phyllobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_343881_2 1609634.A0A0C5ANA6_9VIRU 1.36e-20 93.6 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_343881_7 1609634.A0A0C5AFT2_9VIRU 3.55e-138 401.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_343881_9 1609634.A0A0C5AFV4_9VIRU 2.6e-181 522.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_184852_7 1609634.A0A0C5ANA6_9VIRU 1.51e-21 95.9 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_184852_8 1609634.A0A0C5AFV4_9VIRU 1.75e-187 540.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_258881_7 453591.Igni_1062 5.12e-07 57.0 COG1948@1|root,arCOG04206@2157|Archaea,2XQJU@28889|Crenarchaeota 28889|Crenarchaeota L ERCC4 domain protein - - - ko:K10848 ko03420,ko03460,map03420,map03460 - - - ko00000,ko00001,ko01000,ko03032,ko03400 - - - ERCC4,HHH_5 k59_15158_1 279280.Q6J1R6_9CAUD 7.03e-16 80.5 4QBMX@10239|Viruses,4QV9I@35237|dsDNA viruses no RNA stage,4QQGF@28883|Caudovirales,4QNC1@10744|Podoviridae 10744|Podoviridae S Pfam:Tube - GO:0005575,GO:0019012 - - - - - - - - - - - k59_210935_1 1121406.JAEX01000001_gene220 2.94e-31 127.0 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,42YKK@68525|delta/epsilon subdivisions,2WUDS@28221|Deltaproteobacteria,2M8E7@213115|Desulfovibrionales 28221|Deltaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_284560_1 1548903.A0A0A1IWQ8_9CAUD 1.34e-73 232.0 4QAIK@10239|Viruses,4QPEB@28883|Caudovirales 28883|Caudovirales S phosphoprotein phosphatase activity - - - - - - - - - - - - - k59_137344_1 1423724.BAMM01000010_gene1226 0.000472 48.9 COG1475@1|root,COG1475@2|Bacteria,1TP0I@1239|Firmicutes,4HAC6@91061|Bacilli,3F4RU@33958|Lactobacillaceae 91061|Bacilli K Belongs to the ParB family noc - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_113106_1 1424334.W822_20180 4.8e-11 62.8 COG0582@1|root,COG0582@2|Bacteria,1QB64@1224|Proteobacteria,2VRP1@28216|Betaproteobacteria,3T1G1@506|Alcaligenaceae 28216|Betaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k59_125736_1 398578.Daci_1943 3.72e-51 191.0 COG3064@1|root,COG3064@2|Bacteria,1R6JV@1224|Proteobacteria 1224|Proteobacteria M Membrane - - - - - - - - - - - - - k59_284561_2 563192.HMPREF0179_01740 8.41e-47 165.0 28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria,42QIP@68525|delta/epsilon subdivisions,2WKTY@28221|Deltaproteobacteria,2MA65@213115|Desulfovibrionales 28221|Deltaproteobacteria S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_101332_1 105154.Q9MBU6_9VIRU 3.46e-55 190.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_223014_1 1618248.A0A0C5IB82_9CIRC 1.96e-13 70.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_4168_1 1692252.A0A0K1RL35_9CIRC 1.78e-55 184.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_4168_2 1692242.A0A0K1RKZ2_9CIRC 1.13e-24 107.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_4168_3 1618248.A0A0C5IB82_9CIRC 4.19e-32 122.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_286222_2 1123008.KB905702_gene2321 1.51e-26 103.0 2EAUN@1|root,334W9@2|Bacteria,4NW5Y@976|Bacteroidetes,2G1QR@200643|Bacteroidia,23121@171551|Porphyromonadaceae 976|Bacteroidetes - - - - - - - - - - - - - - - k59_235843_2 2003327.CAPSD_BPCHP 7.54e-27 114.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_309151_1 266835.14027380 7.19e-33 124.0 COG3756@1|root,COG3756@2|Bacteria,1R95D@1224|Proteobacteria,2UMRW@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF1376) - - - - - - - - - - - - DUF1376 k59_151016_1 391616.OA238_c38720 1.37e-23 97.8 COG3409@1|root,COG4322@1|root,COG3409@2|Bacteria,COG4322@2|Bacteria,1NCJ6@1224|Proteobacteria,2U1UB@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_1 k59_151016_2 398525.KB900701_gene5067 8.39e-28 102.0 2BZTS@1|root,33131@2|Bacteria,1NBBP@1224|Proteobacteria,2UIZA@28211|Alphaproteobacteria,3K1K3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_235847_2 716928.AJQT01000109_gene1217 2.68e-43 146.0 2FEUE@1|root,346TC@2|Bacteria,1MZPB@1224|Proteobacteria,2UC4Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_199592_8 1379712.S5TMV9_9CIRC 9.74e-17 89.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_175587_1 1123052.AUDF01000002_gene631 3.68e-56 188.0 COG2089@1|root,COG2089@2|Bacteria,2GJC9@201174|Actinobacteria,4FKD6@85023|Microbacteriaceae 201174|Actinobacteria M NeuB family - - 2.5.1.132,2.5.1.56,2.5.1.57 ko:K05304 ko00520,ko01100,map00520,map01100 - R04435 RC00159 ko00000,ko00001,ko01000 - - - AP_endonuc_2,NeuB,SAF k59_90473_1 1219045.BV98_000569 3.17e-38 162.0 COG0358@1|root,COG3378@1|root,COG0358@2|Bacteria,COG3378@2|Bacteria,1MV7I@1224|Proteobacteria,2TRS2@28211|Alphaproteobacteria,2K264@204457|Sphingomonadales 204457|Sphingomonadales L D5 N terminal like - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,Prim-Pol k59_90473_3 665942.HMPREF1022_02898 1.47e-68 226.0 COG0863@1|root,COG0863@2|Bacteria,1PCS6@1224|Proteobacteria,42XRD@68525|delta/epsilon subdivisions,2WW4I@28221|Deltaproteobacteria,2MDD6@213115|Desulfovibrionales 28221|Deltaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_66375_1 78245.Xaut_3704 6.72e-67 217.0 COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,3EYR8@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_200924_32 49964.Q94MR5_9CAUD 3.49e-08 63.2 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNBD@10744|Podoviridae 10744|Podoviridae S outer membrane - - - - - - - - - - - - - k59_200924_34 375286.mma_2198 2.85e-110 345.0 28QU5@1|root,2ZD9H@2|Bacteria,1RAU8@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_200924_45 652103.Rpdx1_2524 2.71e-49 163.0 2EP91@1|root,33GVT@2|Bacteria,1NHCT@1224|Proteobacteria,2UJY7@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_200924_46 375286.mma_2202 1.56e-112 336.0 28NGF@1|root,2Z9HT@2|Bacteria,1R9QF@1224|Proteobacteria,2VPSU@28216|Betaproteobacteria,47599@75682|Oxalobacteraceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_55137_2 1410665.JNKR01000017_gene212 1.05e-42 167.0 COG0272@1|root,COG0507@1|root,COG0272@2|Bacteria,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4H24B@909932|Negativicutes 909932|Negativicutes L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k59_176998_1 526227.Mesil_2398 1.41e-12 77.0 2DR99@1|root,33ARP@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_213883_1 1158150.KB906242_gene236 6.95e-44 152.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,1SQ0T@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_370712_1 1314.HKU360_01215 3.21e-26 117.0 COG5283@1|root,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,4HEHJ@91061|Bacilli 91061|Bacilli D Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_335031_1 1385658.U5KNR1_9VIRU 4.16e-24 103.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_274048_1 444875.E3SMD8_9CAUD 7.08e-44 147.0 4QD0J@10239|Viruses,4R0A5@35237|dsDNA viruses no RNA stage,4QSK9@28883|Caudovirales,4QNR4@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_214107_1 525264.HMPREF0305_12478 0.00074 44.3 2AV5J@1|root,31KVW@2|Bacteria,2HPM8@201174|Actinobacteria,22PZ7@1653|Corynebacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_128572_2 1618258.A0A0C5I9K3_9CIRC 3.37e-33 129.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_287966_1 658401.C7F4B8_9CAUD 1.21e-10 68.6 4QH5W@10239|Viruses,4QYFG@35237|dsDNA viruses no RNA stage,4QQD8@28883|Caudovirales,4QN2T@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_166110_1 1498011.A0A096XUU0_9CAUD 6.54e-91 281.0 4QG38@10239|Viruses,4QQVI@28883|Caudovirales,4QNWM@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_130131_1 1788447.A0A190WHJ9_9CIRC 3.99e-62 199.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_154413_1 351016.RAZWK3B_14868 1.38e-39 146.0 COG1475@1|root,COG1475@2|Bacteria,1N9EP@1224|Proteobacteria,2UM9Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria K DNA binding - - - - - - - - - - - - HTH_23 k59_289552_1 344747.PM8797T_10219 2.46e-132 389.0 COG2401@1|root,COG2401@2|Bacteria,2IYZ0@203682|Planctomycetes 203682|Planctomycetes K acetyltransferase - - - - - - - - - - - - - k59_300503_2 145579.C_BPPHM 7.86e-15 71.2 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_300503_3 186617.M9M8L2_9VIRU 1.13e-60 204.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_227496_1 1196029.ALIM01000051_gene74 2.2e-13 72.0 COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,1ZCZ4@1386|Bacillus 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily sigW - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k59_69299_1 397945.Aave_2383 2.06e-20 96.3 COG0454@1|root,COG0503@1|root,COG0827@1|root,COG0456@2|Bacteria,COG0503@2|Bacteria,COG0827@2|Bacteria,1PE9Y@1224|Proteobacteria,2VP0T@28216|Betaproteobacteria,4AGXR@80864|Comamonadaceae 28216|Betaproteobacteria K Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis - - - - - - - - - - - - - k59_312143_4 1234888.K0A2J2_9VIRU 5e-174 505.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_202655_1 178901.AmDm5_1921 1.28e-09 64.3 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,2U0EG@28211|Alphaproteobacteria,2JSYH@204441|Rhodospirillales 204441|Rhodospirillales S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_227500_1 1234888.K0A2J2_9VIRU 3.71e-61 206.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_372366_1 411460.RUMTOR_01356 1.5e-59 211.0 28JED@1|root,2Z98K@2|Bacteria,1TW1U@1239|Firmicutes,24CFD@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - GerE k59_238837_2 1127695.HMPREF9163_00377 2.23e-11 66.2 2DHKB@1|root,32U9C@2|Bacteria,1VBER@1239|Firmicutes,4H5W5@909932|Negativicutes 909932|Negativicutes - - - - - - - - - - - - - - DUF669 k59_227501_2 1005395.CSV86_13860 1.07e-42 151.0 COG0338@1|root,COG0338@2|Bacteria 2|Bacteria L D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_94102_2 1141106.CAIB01000133_gene1116 1.11e-10 66.6 COG1372@1|root,COG1783@1|root,COG1372@2|Bacteria,COG1783@2|Bacteria,1TRQP@1239|Firmicutes,4HCUQ@91061|Bacilli,4H1J5@90964|Staphylococcaceae 91061|Bacilli L Terminase RNAseH like domain - - - - - - - - - - - - Terminase_3,Terminase_3C k59_384380_1 428125.CLOLEP_01423 2.15e-34 132.0 2E2JP@1|root,32XP4@2|Bacteria,1VAIM@1239|Firmicutes,24PPR@186801|Clostridia,3WI4W@541000|Ruminococcaceae 186801|Clostridia S Phage tail protein - - - - - - - - - - - - Sipho_tail k59_166125_2 1219035.NT2_13_00580 7.81e-31 123.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_179127_1 1167006.UWK_02006 4.1e-10 62.8 COG0463@1|root,COG0463@2|Bacteria,1QYVD@1224|Proteobacteria,43CR9@68525|delta/epsilon subdivisions,2X8N9@28221|Deltaproteobacteria,2MPQ0@213118|Desulfobacterales 68525|delta/epsilon subdivisions M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k59_130367_1 1692256.A0A0K1RL85_9CIRC 3.54e-13 69.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_179128_1 1380394.JADL01000006_gene5303 3.12e-18 92.0 COG0468@1|root,COG0468@2|Bacteria,1PK58@1224|Proteobacteria,2UB77@28211|Alphaproteobacteria,2JV8V@204441|Rhodospirillales 204441|Rhodospirillales L AAA domain - - - - - - - - - - - - AAA_24 k59_373969_1 1300350.DSW25_10755 6.64e-17 82.8 COG3914@1|root,COG3914@2|Bacteria,1RC2I@1224|Proteobacteria,2U5BE@28211|Alphaproteobacteria,3ZVJF@60136|Sulfitobacter 28211|Alphaproteobacteria O O-linked N-acetylglucosamine transferase SPINDLY family - - - - - - - - - - - - - k59_143622_1 1239962.C943_04156 7.49e-43 161.0 COG1061@1|root,COG1061@2|Bacteria,4NECV@976|Bacteroidetes,47NKQ@768503|Cytophagia 976|Bacteroidetes L Type III restriction enzyme, res subunit - - - - - - - - - - - - DUF3427,Helicase_C,PLDc_2,ResIII,WG_beta_rep k59_95915_2 1121344.JHZO01000006_gene1818 1.85e-26 107.0 28MKK@1|root,2ZAWR@2|Bacteria,1UYAT@1239|Firmicutes,24GI2@186801|Clostridia,3WR2E@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_338359_1 49964.Q94MS4_9CAUD 2.91e-43 160.0 4QCUF@10239|Viruses,4QV7U@35237|dsDNA viruses no RNA stage,4QQ89@28883|Caudovirales,4QNCY@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_302277_1 438753.AZC_3607 1.52e-70 240.0 COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria,2U1JR@28211|Alphaproteobacteria 28211|Alphaproteobacteria K DNA-dependent RNA polymerase - - - - - - - - - - - - RNA_pol,RPOL_N k59_9607_1 1788447.A0A190WHJ9_9CIRC 9.34e-82 251.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_252706_2 1423775.BAMN01000011_gene594 9.51e-06 49.3 2DR9Y@1|root,33AUY@2|Bacteria 2|Bacteria L HNH endonuclease domain protein - - - - - - - - - - - - HNH_3,NUMOD4 k59_264498_2 556268.OFAG_02256 3.72e-41 141.0 2A24E@1|root,30QER@2|Bacteria,1NZ1I@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_20871_3 1229205.BUPH_03810 3.72e-22 89.7 2E3RU@1|root,32YPG@2|Bacteria,1NAWV@1224|Proteobacteria,2VSXN@28216|Betaproteobacteria,1K9YG@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_204436_1 401526.TcarDRAFT_1293 2.69e-23 108.0 COG0503@1|root,COG0741@1|root,COG0503@2|Bacteria,COG0741@2|Bacteria,1TSYQ@1239|Firmicutes,4H5A6@909932|Negativicutes 909932|Negativicutes F protein secretion by the type IV secretion system - - - - - - - - - - - - SLT k59_252855_1 1165094.RINTHH_3920 3.74e-32 124.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_133554_1 691965.D4P7E6_9CAUD 5.34e-05 47.4 4QAK6@10239|Viruses,4R01K@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_120249_2 195105.CN97_00790 3.37e-66 226.0 COG3567@1|root,COG3567@2|Bacteria,1R45U@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF1073) - - - ko:K09961 - - - - ko00000 - - - DUF1073 k59_22251_2 1449347.JQLN01000004_gene7007 8.28e-27 109.0 COG5323@1|root,COG5323@2|Bacteria,2I1XF@201174|Actinobacteria,2M5NQ@2063|Kitasatospora 201174|Actinobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_205833_2 224911.27349518 3.15e-09 59.7 29WU4@1|root,30IFI@2|Bacteria,1Q0E1@1224|Proteobacteria,2UFWS@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_181985_2 1380894.S5TR92_9CIRC 6.44e-42 153.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_265943_1 1452718.JBOY01000021_gene717 1.46e-36 136.0 2DKZ2@1|root,32UFZ@2|Bacteria,1N5GS@1224|Proteobacteria,1SP03@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - PDDEXK_1 k59_47932_1 1121396.KB893070_gene1348 2.77e-60 201.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,42QA8@68525|delta/epsilon subdivisions,2WJBW@28221|Deltaproteobacteria,2MIKF@213118|Desulfobacterales 28221|Deltaproteobacteria S PFAM ATPase associated with various cellular activities - - - - - - - - - - - - AAA_3,AAA_5 k59_242027_1 196367.JNFG01000015_gene3881 2.33e-12 76.6 2DM1V@1|root,31D5J@2|Bacteria,1QWVQ@1224|Proteobacteria,2WH21@28216|Betaproteobacteria,1K6TV@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_169143_1 1609634.A0A0C5AFV4_9VIRU 7.14e-37 140.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_11055_1 1123487.KB892865_gene1375 1.77e-39 142.0 28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria,2VPRP@28216|Betaproteobacteria,2KZJK@206389|Rhodocyclales 206389|Rhodocyclales S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_363096_1 545695.TREAZ_0592 4.92e-56 189.0 COG1196@1|root,COG1196@2|Bacteria 2|Bacteria D nuclear chromosome segregation - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - Dam,PhageMin_Tail k59_190197_1 1120941.AUBL01000026_gene2 1.17e-62 211.0 COG2304@1|root,COG2304@2|Bacteria,2HMJ4@201174|Actinobacteria,4D74C@85005|Actinomycetales 201174|Actinobacteria S TROVE domain - - - - - - - - - - - - TROVE k59_11270_1 460265.Mnod_5105 1.71e-74 234.0 COG4422@1|root,COG4422@2|Bacteria,1MXQI@1224|Proteobacteria,2TVMB@28211|Alphaproteobacteria,1JUZR@119045|Methylobacteriaceae 28211|Alphaproteobacteria S PFAM Gp37Gp68 family protein - - - - - - - - - - - - DUF5131 k59_133790_1 742740.HMPREF9474_02303 1.59e-52 187.0 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia,221YV@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_340337_1 2003327.CAPSD_BPCHP 5.35e-14 74.7 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_303932_1 1385658.U5KPZ6_9VIRU 1.12e-45 161.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_145977_1 1618240.A0A0C5IMJ1_9CIRC 1.11e-51 174.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_316063_1 1322246.BN4_11055 6.19e-12 77.4 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,2M7UN@213115|Desulfovibrionales 28221|Deltaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_194589_2 1636270.A0A0E3JSB2_9CAUD 1.56e-06 58.9 4QBFN@10239|Viruses,4QPTW@28883|Caudovirales,4QNPZ@10744|Podoviridae 10744|Podoviridae S Phage stabilisation protein - - - - - - - - - - - - - k59_194608_2 1449357.JQLK01000001_gene1384 1.03e-46 172.0 COG3864@1|root,COG3864@2|Bacteria,1WJSF@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N k59_121702_2 1692249.A0A0K1RLN8_9CIRC 4.63e-50 169.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_48859_1 1385658.U5KPZ6_9VIRU 6.39e-143 425.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_303973_1 1279015.KB908455_gene1439 3.64e-21 88.6 COG4570@1|root,COG4570@2|Bacteria,1N92D@1224|Proteobacteria,1SDZ5@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC rusA GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008821,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.1.22.4 ko:K01160 - - - - ko00000,ko01000,ko03400 - - - RusA k59_291779_1 1609634.A0A0C5AFT2_9VIRU 4.83e-82 254.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_279737_1 1162305.I3PV34_9CAUD 5.41e-14 70.1 4QAZF@10239|Viruses,4QUTY@35237|dsDNA viruses no RNA stage,4QPH6@28883|Caudovirales,4QNEM@10744|Podoviridae 10744|Podoviridae S Protein of unknwon function (DUF3310) - - - - - - - - - - - - - k59_279737_4 445693.E3SN95_9CAUD 2.8e-17 79.3 4QASP@10239|Viruses,4QVR8@35237|dsDNA viruses no RNA stage,4QR4Z@28883|Caudovirales,4QNQ0@10744|Podoviridae 10744|Podoviridae S deoxyribonuclease IV (phage-T4-induced) activity - - - - - - - - - - - - - k59_279737_5 182217.HCW_03660 1.93e-11 70.5 COG0258@1|root,COG0258@2|Bacteria 2|Bacteria L nuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_340367_2 1385658.U5KPZ6_9VIRU 1.22e-184 536.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_340367_4 105154.Q9MBU2_9VIRU 1.55e-16 78.6 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_231245_1 935261.JAGL01000009_gene1165 2.82e-72 238.0 COG0209@1|root,COG0209@2|Bacteria,1PM78@1224|Proteobacteria,2UZUM@28211|Alphaproteobacteria,43QGW@69277|Phyllobacteriaceae 28211|Alphaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - - - - - - - - - - - - k59_133977_6 65071.PYU1_T010251 6.79e-07 61.6 KOG2373@1|root,KOG2373@2759|Eukaryota,1MBHA@121069|Pythiales 121069|Pythiales L Twinkle protein. Source PGD - - - - - - - - - - - - AAA_25,Toprim_2 k59_340558_1 1234888.K0A2J2_9VIRU 1.17e-66 219.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_304300_4 1472912.A0A023NH00_9CAUD 6.25e-22 99.4 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QPEB@28883|Caudovirales 28883|Caudovirales S phosphoprotein phosphatase activity - - - - - - - - - - - - - k59_304300_5 562742.F4YXL8_9CAUD 1.71e-172 502.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_328562_3 105154.Q9MBU6_9VIRU 1.07e-180 527.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_12494_1 1123312.KB904575_gene69 5.41e-42 164.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,4H9Z7@91061|Bacilli 91061|Bacilli L DNA polymerase polA_2 - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_134007_1 105154.Q9MBU6_9VIRU 1.3e-130 396.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_61294_1 913865.DOT_1568 8.09e-67 215.0 28MC2@1|root,2ZAQD@2|Bacteria,1VSEU@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - k59_146273_1 428125.CLOLEP_01422 3.17e-62 227.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,3WN92@541000|Ruminococcaceae 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_62236_1 467481.B0VK31_9CAUD 2.2e-40 155.0 4QAYV@10239|Viruses,4QUZ7@35237|dsDNA viruses no RNA stage,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - k59_62236_2 1392838.AWNM01000004_gene1802 2.64e-09 59.7 COG3740@1|root,COG3740@2|Bacteria,1NHKT@1224|Proteobacteria,2VV07@28216|Betaproteobacteria,3T8GV@506|Alcaligenaceae 28216|Betaproteobacteria S Caudovirus prohead serine protease - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78 k59_220205_6 1385658.U5KPZ6_9VIRU 9e-137 414.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_317280_3 1100720.ALKN01000018_gene1738 4.14e-120 370.0 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,2VQF3@28216|Betaproteobacteria,4ADUP@80864|Comamonadaceae 28216|Betaproteobacteria L Helicase conserved C-terminal domain - - - - - - - - - - - - Helicase_C,ResIII,UPF0547 k59_232063_2 1788443.A0A190WHB4_9CIRC 3.39e-26 107.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_281186_2 679926.Mpet_2297 3.18e-36 137.0 COG0863@1|root,arCOG00115@2157|Archaea,2Y00D@28890|Euryarchaeota 28890|Euryarchaeota L modification methylase - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_171325_3 645099.MREP_BBTVA 3.24e-56 191.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_377997_1 172088.AUGA01000033_gene4632 9.02e-56 188.0 28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria,2U265@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_207931_1 645099.MREP_BBTVA 2.52e-33 130.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_13009_1 691965.D4P7E6_9CAUD 2.3e-11 71.2 4QAK6@10239|Viruses,4R01K@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_13009_15 691965.D4P7I3_9CAUD 0.0 1465.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_13009_16 665950.HMPREF1025_01958 1.44e-43 148.0 2E0G5@1|root,32W28@2|Bacteria,1VAS0@1239|Firmicutes,24NYA@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_354723_1 1122243.KB903787_gene4 1.13e-06 52.4 COG3108@1|root,COG3108@2|Bacteria,1RICX@1224|Proteobacteria,1S6D5@1236|Gammaproteobacteria,3NSUJ@468|Moraxellaceae 1236|Gammaproteobacteria S D-alanyl-D-alanine carboxypeptidase - - - ko:K17733 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M15_4 k59_257378_2 1692252.A0A0K1RL35_9CIRC 1.35e-29 120.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_318492_4 1460635.JCM19038_645 2.54e-19 86.3 COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli 91061|Bacilli L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_293898_4 1609634.A0A0C5AFT2_9VIRU 1.78e-55 190.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_293898_6 1385658.U5KPZ6_9VIRU 2.65e-172 501.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_63300_3 1420600.W5RNT1_9CIRC 8.74e-16 78.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_293899_1 348824.LPU83_1717 2.4e-19 86.7 28PTM@1|root,2ZCEU@2|Bacteria,1R5DD@1224|Proteobacteria,2TVG7@28211|Alphaproteobacteria,4BGD7@82115|Rhizobiaceae 28211|Alphaproteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_282671_1 1238450.VIBNISOn1_1190023 4.04e-28 118.0 2F6W9@1|root,33ZCB@2|Bacteria,1NZ0D@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_75244_1 1415780.JPOG01000001_gene1761 2.84e-08 62.8 COG3170@1|root,COG3170@2|Bacteria,1N4R0@1224|Proteobacteria,1RY0B@1236|Gammaproteobacteria,1X91G@135614|Xanthomonadales 135614|Xanthomonadales NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - k59_209351_1 665942.HMPREF1022_03280 4.33e-19 91.3 2DUXE@1|root,32UY2@2|Bacteria,1N2YI@1224|Proteobacteria,430A8@68525|delta/epsilon subdivisions,2WVIN@28221|Deltaproteobacteria,2MCZ8@213115|Desulfovibrionales 28221|Deltaproteobacteria S Phage T7 capsid assembly protein - - - - - - - - - - - - Phage_T7_Capsid k59_197798_2 1279019.ARQK01000045_gene517 3.16e-40 150.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1R97W@1224|Proteobacteria,1TK9M@1236|Gammaproteobacteria,1X0PG@135613|Chromatiales 135613|Chromatiales D Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_149022_1 1986029.Q9MBM7_9VIRU 5.88e-19 85.9 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_149022_2 1385658.U5KPZ6_9VIRU 1.79e-65 216.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_258505_12 102125.Xen7305DRAFT_00008360 5.19e-22 104.0 COG4886@1|root,COG4886@2|Bacteria,1G0NZ@1117|Cyanobacteria,3VKP8@52604|Pleurocapsales 1117|Cyanobacteria S Leucine-rich repeat (LRR) protein - - - ko:K13730 ko05100,map05100 - - - ko00000,ko00001 - - - - k59_64490_2 426117.M446_3418 6.44e-57 204.0 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,2TUXC@28211|Alphaproteobacteria,1JTIG@119045|Methylobacteriaceae 28211|Alphaproteobacteria L DEAD DEAH box helicase domain protein - - - ko:K19789 - - - - ko00000,ko03400 - - - DUF3427,HIT,Helicase_C,PLDc_2,ResIII,UPF0547 k59_88580_1 36875.HQ29_02650 8.39e-05 51.2 COG0454@1|root,COG0553@1|root,COG0456@2|Bacteria,COG0553@2|Bacteria,4NZK9@976|Bacteroidetes,2FRRF@200643|Bacteroidia,22Z0V@171551|Porphyromonadaceae 976|Bacteroidetes KL acetyltransferase - - - - - - - - - - - - - k59_283995_1 691965.D4P7L7_9CAUD 1.4e-199 593.0 4QB9J@10239|Viruses,4QXFE@35237|dsDNA viruses no RNA stage,4QS1Z@28883|Caudovirales,4QN8F@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_295121_1 1234888.K0A2J2_9VIRU 1.66e-24 106.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_136915_2 1296654.S5MLY3_9CAUD 0.000171 46.6 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QKM7@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k59_307450_1 1217720.ALOX01000106_gene1193 2.19e-35 138.0 28IJ1@1|root,2Z8K0@2|Bacteria,1R5PC@1224|Proteobacteria,2U0RA@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_331863_2 768066.HELO_2115 9.74e-31 115.0 COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria 1224|Proteobacteria KT HNH endonuclease - - - - - - - - - - - - HNH_3 k59_331863_6 1380347.JNII01000006_gene1446 2.56e-64 250.0 COG1749@1|root,COG2372@1|root,COG5184@1|root,COG1749@2|Bacteria,COG2372@2|Bacteria,COG5184@2|Bacteria,2I2X3@201174|Actinobacteria,4EUDH@85013|Frankiales 201174|Actinobacteria N Bacterial Ig-like domain - - - - - - - - - - - - Big_5,DUF4082,Mo-co_dimer,fn3 k59_380076_2 1692249.A0A0K1RL40_9CIRC 1.62e-07 56.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_162807_5 1121106.JQKB01000016_gene5268 3.17e-41 152.0 COG0500@1|root,COG2520@1|root,COG2226@2|Bacteria,COG2520@2|Bacteria,1RIYU@1224|Proteobacteria,2U2ZF@28211|Alphaproteobacteria,2JSTB@204441|Rhodospirillales 204441|Rhodospirillales Q Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 k59_199111_2 1618241.A0A0C5I2I4_9CIRC 2.89e-38 145.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_102037_2 40571.JOEA01000004_gene6228 0.000202 49.3 COG0110@1|root,COG0110@2|Bacteria,2IDUP@201174|Actinobacteria,4E2NR@85010|Pseudonocardiales 201174|Actinobacteria S sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family - - - - - - - - - - - - Hexapep,Hexapep_2 k59_296397_1 1385658.U5KPZ6_9VIRU 9.19e-47 170.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_41068_2 461711.A0A096VKV8_9CAUD 4.33e-24 106.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_272025_1 1054461.G0XNT8_9CAUD 7.98e-21 92.8 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_272025_2 207656.S6ANT1_9CAUD 2.35e-19 87.8 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QI6J@10662|Myoviridae 10662|Myoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_176460_1 1692252.A0A0K1RL35_9CIRC 3.84e-79 243.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_176461_1 1408428.JNJP01000003_gene3493 5.6e-68 215.0 COG0270@1|root,COG0270@2|Bacteria 2|Bacteria L DNA (cytosine-5-)-methyltransferase activity - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_30862_2 158190.SpiGrapes_2410 4.12e-25 103.0 COG2856@1|root,COG3093@1|root,COG2856@2|Bacteria,COG3093@2|Bacteria,2J9C8@203691|Spirochaetes 203691|Spirochaetes K Helix-turn-helix - - - ko:K18831 - - - - ko00000,ko02048,ko03000 - - - HTH_3,Peptidase_M78 k59_346507_1 105154.Q9MBU6_9VIRU 1.35e-97 304.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_334494_2 1234880.K0A2H8_9CIRC 7.77e-13 73.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_103556_1 1117943.SFHH103_00150 2e-10 67.4 2DPZ1@1|root,3340X@2|Bacteria,1R2EE@1224|Proteobacteria,2TZIB@28211|Alphaproteobacteria,4BP2Q@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_322573_1 1231190.NA8A_23312 8.58e-07 57.8 COG1196@1|root,COG1196@2|Bacteria,1R27D@1224|Proteobacteria,2TZCI@28211|Alphaproteobacteria,43IIZ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria D Prophage tail length tape measure protein - - - - - - - - - - - - TMP_2 k59_382671_1 1379709.S5TMV0_9CIRC 1.23e-10 67.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_334496_1 1111732.AZOD01000014_gene1501 1.52e-24 105.0 COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,1RMHP@1236|Gammaproteobacteria,1X49Q@135614|Xanthomonadales 135614|Xanthomonadales L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071496 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA k59_310204_1 42565.FP66_04545 4.49e-78 254.0 COG0740@1|root,COG0740@2|Bacteria,1MUQ9@1224|Proteobacteria,1RRQA@1236|Gammaproteobacteria,1XQSC@135619|Oceanospirillales 135619|Oceanospirillales OU Belongs to the peptidase S14 family - - - - - - - - - - - - CLP_protease k59_164364_1 1449063.JMLS01000027_gene39 2.18e-12 69.3 COG0500@1|root,COG2226@2|Bacteria,1TXXF@1239|Firmicutes,4I701@91061|Bacilli,26VPX@186822|Paenibacillaceae 91061|Bacilli Q Pfam Transposase IS66 - - - - - - - - - - - - Methyltransf_11 k59_103561_2 49964.Q94MS1_9CAUD 1.18e-62 203.0 4QB4H@10239|Viruses,4QYQI@35237|dsDNA viruses no RNA stage,4QUAR@28883|Caudovirales,4QNUV@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_17302_1 1385658.U5KPZ6_9VIRU 2.71e-47 167.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_359589_1 243233.MCA1516 1.14e-14 79.0 COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,1S4C5@1236|Gammaproteobacteria 1236|Gammaproteobacteria M tpr domain protein - - - - - - - - - - - - DUF29,Glyco_transf_9,TPR_1,TPR_16,TPR_19,TPR_2,TPR_8 k59_43950_1 1380346.JNIH01000064_gene5195 0.00041 43.5 2DNZ6@1|root,32ZV6@2|Bacteria,2GR6G@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_43950_3 1517681.HW45_02700 9.08e-29 120.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1QZAD@1224|Proteobacteria,1RYP3@1236|Gammaproteobacteria 1236|Gammaproteobacteria D nuclear chromosome segregation - - - - - - - - - - - - - k59_104763_1 1475143.W8SNN0_9CIRC 1.02e-24 108.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_288911_1 1165094.RINTHH_3920 2.04e-13 71.6 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_336020_1 626887.J057_01665 1.17e-57 200.0 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,1RR0M@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_178217_2 1068980.ARVW01000001_gene5467 9.32e-05 53.9 COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria,4DZUE@85010|Pseudonocardiales 201174|Actinobacteria G Beta galactosidase small chain - - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Laminin_G_3,NPCBM,NPCBM_assoc k59_383736_2 178901.AmDm5_1921 1.86e-31 135.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,2U0EG@28211|Alphaproteobacteria,2JSYH@204441|Rhodospirillales 204441|Rhodospirillales S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_165600_3 1331060.RLDS_03865 5.24e-21 88.6 2CMPB@1|root,32SF8@2|Bacteria,1RCNY@1224|Proteobacteria,2UPH0@28211|Alphaproteobacteria,2K2QJ@204457|Sphingomonadales 204457|Sphingomonadales S Transcription elongation protein SprT - - - - - - - - - - - - - k59_300068_1 1618248.A0A0C5IB82_9CIRC 1.16e-15 76.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_348235_1 1732201.A0A0N9N7I3_9CIRC 1.23e-19 92.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_129671_2 1506583.JQJY01000003_gene3390 1.99e-08 61.2 COG1196@1|root,COG1511@1|root,COG1196@2|Bacteria,COG1511@2|Bacteria 2|Bacteria Q domain protein yjeP - - ko:K01421,ko:K02004,ko:K02316,ko:K05802,ko:K10953,ko:K12684,ko:K22051 ko03030,ko05110,map03030,map05110 M00258 - - ko00000,ko00001,ko00002,ko01000,ko02000,ko02042,ko02044,ko03032 1.A.23.1.1,1.A.23.1.2,1.A.23.1.3,1.B.12.4,3.A.1 - - AAA_15,MS_channel,MscS_TM,MscS_porin k59_116813_3 1234888.K0A2J2_9VIRU 8.2e-148 437.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_116813_7 1234888.K0A2R8_9VIRU 1.8e-43 155.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_142986_1 395493.BegalDRAFT_1453 4.54e-22 101.0 COG0582@1|root,COG0582@2|Bacteria,1MWBN@1224|Proteobacteria,1RPD0@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k59_290390_1 406818.XBJ1_1276 1.03e-28 126.0 COG1196@1|root,COG5281@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5281@2|Bacteria,COG5283@2|Bacteria,1R47M@1224|Proteobacteria,1RYE6@1236|Gammaproteobacteria 1236|Gammaproteobacteria D COG5281, Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail,Phage_HK97_TLTM,Tape_meas_lam_C k59_373331_1 373994.Riv7116_2243 3.16e-08 59.7 COG2242@1|root,COG2242@2|Bacteria,1GAGS@1117|Cyanobacteria,1HQ7G@1161|Nostocales 1117|Cyanobacteria H Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 k59_106230_5 1197951.I6RT34_9CAUD 3.52e-215 612.0 4QGAG@10239|Viruses,4R0KB@35237|dsDNA viruses no RNA stage,4QUA4@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_106230_6 1161935.H9D1H5_9CAUD 5.68e-160 477.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales,4QNDH@10744|Podoviridae 10744|Podoviridae S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_106230_8 1197951.I6S6J9_9CAUD 2.67e-09 63.5 4QE6E@10239|Viruses,4QV23@35237|dsDNA viruses no RNA stage,4QTFG@28883|Caudovirales 28883|Caudovirales S protein dimerization activity - - - - - - - - - - - - - k59_70384_1 596152.DesU5LDRAFT_1418 4.1e-12 65.5 COG1896@1|root,COG1896@2|Bacteria,1RACF@1224|Proteobacteria,431GD@68525|delta/epsilon subdivisions,2WWJC@28221|Deltaproteobacteria 28221|Deltaproteobacteria S hydrolases of HD superfamily - - - ko:K06952 - - - - ko00000 - - - - k59_34082_2 412597.AEPN01000003_gene3392 9.46e-11 67.4 28H5T@1|root,2Z7IB@2|Bacteria,1N7V9@1224|Proteobacteria,2TTZQ@28211|Alphaproteobacteria,2PUKQ@265|Paracoccus 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_290564_1 1692249.A0A0K1RL40_9CIRC 4.62e-17 85.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_290564_3 1692253.A0A0K1RLM4_9CIRC 1.15e-13 70.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_228830_1 1449126.JQKL01000051_gene3168 1.21e-10 64.3 2CK39@1|root,32SBG@2|Bacteria,1V8KG@1239|Firmicutes,249UQ@186801|Clostridia 186801|Clostridia S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 k59_228832_2 641112.ACOK01000086_gene3447 1.61e-15 80.9 COG3866@1|root,COG4677@1|root,COG3866@2|Bacteria,COG4677@2|Bacteria,1TSCD@1239|Firmicutes,24AHP@186801|Clostridia,3WHG8@541000|Ruminococcaceae 186801|Clostridia G Pectinesterase - - - - - - - - - - - - Pectinesterase k59_188591_1 1123263.AUKY01000025_gene817 2.35e-20 105.0 COG0749@1|root,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,3VNWN@526524|Erysipelotrichia 526524|Erysipelotrichia L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A k59_47441_2 759938.F5BSB4_9CIRC 1.19e-27 117.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_168626_1 1479238.JQMZ01000001_gene2201 1.64e-69 227.0 COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,2U64S@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_168627_1 428125.CLOLEP_01375 2.36e-51 185.0 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia,3WNBH@541000|Ruminococcaceae 186801|Clostridia S DNA polymerase type-B family - - - - - - - - - - - - - k59_108108_2 396513.SCA_0478 7.1e-34 130.0 COG3935@1|root,COG3935@2|Bacteria,1TSHD@1239|Firmicutes,4HIGY@91061|Bacilli,4GYXQ@90964|Staphylococcaceae 91061|Bacilli L Conserved phage C-terminus (Phg_2220_C) - - - - - - - - - - - - Phage_rep_org_N,Phg_2220_C k59_218671_3 316057.RPD_1319 0.00027 44.3 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,2TT83@28211|Alphaproteobacteria 28211|Alphaproteobacteria S associated with various cellular activities - - - - - - - - - - - - AAA,AAA_3,AAA_5 k59_327414_2 1268072.PSAB_06050 2.39e-12 70.5 COG3728@1|root,COG3728@2|Bacteria,1VAD9@1239|Firmicutes,4HNDI@91061|Bacilli 91061|Bacilli L terminase small subunit - - - ko:K07474 - - - - ko00000 - - - Terminase_2 k59_327414_3 118005.AWNK01000018_gene935 1.56e-123 377.0 COG5565@1|root,COG5565@2|Bacteria 2|Bacteria S DNA packaging protein gp2 - - - - - - - - - - - Terminase_6,Terminase_6C k59_327414_4 570952.ATVH01000011_gene364 1.05e-92 309.0 28P6A@1|root,2ZC10@2|Bacteria,1RBZE@1224|Proteobacteria,2UQEG@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_10659_2 1242864.D187_008748 6.04e-52 178.0 COG0338@1|root,COG0338@2|Bacteria,1Q9YJ@1224|Proteobacteria,438CP@68525|delta/epsilon subdivisions,2X1WK@28221|Deltaproteobacteria,2YWK0@29|Myxococcales 28221|Deltaproteobacteria L D12 class N6 adenine-specific DNA methyltransferase - - - - - - - - - - - - MethyltransfD12 k59_181757_3 1165094.RINTHH_3920 1.05e-19 91.7 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_181757_5 145579.C_BPPHM 1.49e-06 50.1 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_181757_6 105154.Q9MBU6_9VIRU 3.83e-202 580.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_388607_3 44088.Q6VZJ4_CNPV 1.09e-07 54.7 4QB1C@10239|Viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_97647_1 1096546.WYO_0193 1.56e-122 362.0 28JC4@1|root,2Z96S@2|Bacteria,1RI8W@1224|Proteobacteria 1224|Proteobacteria S P22 coat protein-protein 5 domain protein - - - - - - - - - - - - - k59_255539_3 1210884.HG799466_gene12740 1.23e-16 82.4 2C9JF@1|root,32RPD@2|Bacteria 2|Bacteria S Erf family - - - - - - - - - - - - ERF k59_194988_1 2003327.CAPSD_BPCHP 9.55e-22 99.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_352918_1 742733.HMPREF9469_05062 5.47e-154 449.0 COG0553@1|root,COG0553@2|Bacteria,1TS9W@1239|Firmicutes,24CGX@186801|Clostridia,222GT@1506553|Lachnoclostridium 186801|Clostridia KL Helicase conserved C-terminal domain - - - - - - - - - - - - - k59_352918_7 525268.HMPREF0308_2070 6.8e-16 75.5 29XNQ@1|root,30JE6@2|Bacteria,2HZTS@201174|Actinobacteria,22PVB@1653|Corynebacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_49156_8 318464.IO99_13290 6.42e-74 246.0 2DKKM@1|root,309U3@2|Bacteria,1USJV@1239|Firmicutes,24ZBP@186801|Clostridia,36R54@31979|Clostridiaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_328599_2 105154.Q9MBU3_9VIRU 2.07e-11 67.4 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_340990_3 311402.Avi_2984 6.45e-28 130.0 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2TV2W@28211|Alphaproteobacteria,4BIQV@82115|Rhizobiaceae 28211|Alphaproteobacteria S COG4733 Phage-related protein, tail component - - - - - - - - - - - - Phage-tail_3 k59_12799_1 1609634.A0A0C5AFV4_9VIRU 1.87e-103 320.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_231736_3 1609634.A0A0C5AFT2_9VIRU 4.45e-11 70.1 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_110316_1 1609634.A0A0C5AFV4_9VIRU 2.46e-50 181.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_12858_1 1692250.A0A0K1RLR1_9CIRC 2.81e-104 313.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_98114_2 1123499.KB908025_gene1635 1.87e-24 102.0 COG0500@1|root,COG2226@2|Bacteria,1RD1J@1224|Proteobacteria,2VR3V@28216|Betaproteobacteria 28216|Betaproteobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 k59_98114_3 883.DvMF_1653 5.13e-07 54.7 2DHKE@1|root,3004J@2|Bacteria,1Q8XZ@1224|Proteobacteria,42QB1@68525|delta/epsilon subdivisions,2WMCM@28221|Deltaproteobacteria,2MCJA@213115|Desulfovibrionales 28221|Deltaproteobacteria S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 k59_341052_5 472759.Nhal_1137 7.32e-38 132.0 COG1403@1|root,COG1403@2|Bacteria,1N6FJ@1224|Proteobacteria 1224|Proteobacteria V HNH endonuclease - - - - - - - - - - - - - k59_292577_1 1165094.RINTHH_3920 6.95e-121 351.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_377737_4 626522.GCWU000325_02317 2.72e-08 62.0 COG4974@1|root,COG4974@2|Bacteria,4NFAD@976|Bacteroidetes,2FMYI@200643|Bacteroidia 976|Bacteroidetes L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_1,Phage_integrase k59_268253_2 216432.CA2559_11618 4.06e-16 76.6 2DMPB@1|root,32SV8@2|Bacteria,4NSG4@976|Bacteroidetes,1I3FJ@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_61888_4 1072685.IX83_07200 5.37e-26 106.0 2DIG9@1|root,3036R@2|Bacteria,1RBPA@1224|Proteobacteria,2WH3R@28216|Betaproteobacteria,3T9JP@506|Alcaligenaceae 28216|Betaproteobacteria L YqaJ-like viral recombinase domain - - 3.1.11.3 ko:K01143 - - - - ko00000,ko01000 - - - YqaJ k59_122511_1 160488.PP_2284 1.15e-31 125.0 28IA2@1|root,2Z8CQ@2|Bacteria,1PQM2@1224|Proteobacteria,1SN3W@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_25173_2 349163.Acry_1504 2.77e-15 86.7 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,2JQ4K@204441|Rhodospirillales 204441|Rhodospirillales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_231744_1 1692249.A0A0K1RL40_9CIRC 6.09e-35 132.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_365245_6 398578.Daci_3225 6.19e-24 93.6 2EI4V@1|root,33BW7@2|Bacteria,1NN3Z@1224|Proteobacteria 1224|Proteobacteria S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_86457_1 1380355.JNIJ01000010_gene1478 8.12e-25 115.0 COG3598@1|root,COG3598@2|Bacteria,1R5TK@1224|Proteobacteria,2TZF9@28211|Alphaproteobacteria 28211|Alphaproteobacteria L AAA domain - - - - - - - - - - - - AAA_25 k59_86457_2 191610.CATYP_10670 2.66e-63 223.0 COG0749@1|root,COG0749@2|Bacteria,2IG0A@201174|Actinobacteria,22MKV@1653|Corynebacteriaceae 201174|Actinobacteria L DNA polymerase I - 3'-5' exonuclease and polymerase domains - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_1524_1 176299.Atu3854 9.78e-11 72.8 COG3598@1|root,COG3598@2|Bacteria,1R4EA@1224|Proteobacteria,2U8VM@28211|Alphaproteobacteria,4BH1Z@82115|Rhizobiaceae 28211|Alphaproteobacteria L AAA domain - - - - - - - - - - - - AAA_25,Prim-Pol k59_183270_1 1165094.RINTHH_3920 1.38e-60 201.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_281498_2 593750.Metfor_0579 1.46e-06 52.0 arCOG03850@1|root,arCOG03850@2157|Archaea 2157|Archaea S Methyltransferase domain - - - - - - - - - - - - Methyltransf_24,TylF k59_159549_2 1692256.A0A0K1RL85_9CIRC 1.34e-66 217.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_195861_5 1609634.A0A0C5AFV4_9VIRU 2.72e-79 264.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_110866_2 211114.JOEF01000022_gene5584 3.28e-13 78.6 2E9RT@1|root,333Y0@2|Bacteria,2IESW@201174|Actinobacteria,4E4UX@85010|Pseudonocardiales 201174|Actinobacteria S Siphovirus ReqiPepy6 Gp37-like protein - - - - - - - - - - - - Sipho_Gp37 k59_110866_3 1144313.PMI10_02192 5.64e-05 56.2 COG1345@1|root,COG3386@1|root,COG1345@2|Bacteria,COG3386@2|Bacteria,4NM9F@976|Bacteroidetes,1I33Y@117743|Flavobacteriia,2P0DI@237|Flavobacterium 976|Bacteroidetes GN Domain of unknown function (DUF5122) beta-propeller - - - - - - - - - - - - DUF5008,DUF5122,DUF5124 k59_110866_4 1007103.AFHW01000034_gene2067 3.04e-13 83.6 COG3941@1|root,COG3941@2|Bacteria,1V33U@1239|Firmicutes,4HMR7@91061|Bacilli,2711P@186822|Paenibacillaceae 91061|Bacilli S tape measure - - - - - - - - - - - - - k59_147404_18 1166948.JPZL01000002_gene1629 7.72e-19 85.1 2DRN8@1|root,33CCM@2|Bacteria,1NGRN@1224|Proteobacteria 1224|Proteobacteria - - - - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - - k59_147404_19 1429916.X566_20010 7.27e-44 148.0 COG1917@1|root,COG1917@2|Bacteria,1N6Q0@1224|Proteobacteria,2UKI2@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - - k59_244338_1 595536.ADVE02000001_gene2073 1.19e-40 150.0 COG0535@1|root,COG0535@2|Bacteria,1N633@1224|Proteobacteria,2UHNT@28211|Alphaproteobacteria 28211|Alphaproteobacteria S radical SAM domain protein - - - - - - - - - - - - - k59_232401_3 1234888.K0A2J2_9VIRU 2.3e-144 429.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_13269_5 1406840.Q763_11510 2.09e-14 78.6 COG4675@1|root,COG4675@2|Bacteria,4NQJR@976|Bacteroidetes,1I31T@117743|Flavobacteriia,2NX1Q@237|Flavobacterium 976|Bacteroidetes S PFAM phage Tail Collar domain - - - - - - - - - - - - Collar k59_13269_9 1341151.ASZU01000008_gene1553 1.29e-08 60.5 COG3409@1|root,COG5632@1|root,COG3409@2|Bacteria,COG5632@2|Bacteria,1V7KT@1239|Firmicutes,4HJ9N@91061|Bacilli,27BVQ@186824|Thermoactinomycetaceae 91061|Bacilli M Ami_2 - - - - - - - - - - - - Amidase_2,DUF3597,PG_binding_1,SH3_5,SPOR k59_98754_2 700598.Niako_7157 5.04e-10 68.9 COG4886@1|root,COG4886@2|Bacteria 2|Bacteria S regulation of response to stimulus - - - - - - - - - - - - Flg_new,LRR_5,MucBP k59_147816_21 986075.CathTA2_0677 8.12e-19 101.0 COG0741@1|root,COG4942@1|root,COG0741@2|Bacteria,COG4942@2|Bacteria,1V8NJ@1239|Firmicutes,4HKSS@91061|Bacilli 91061|Bacilli D Transglycosylase SLT domain - - - - - - - - - - - - Peptidase_M23,SLT_2 k59_135676_1 1234888.K0A2J2_9VIRU 1.13e-93 293.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_172272_2 1788439.A0A190WHD0_9CIRC 1.09e-17 89.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_354650_5 1385658.U5KPZ6_9VIRU 1.21e-148 444.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_330482_1 1237500.ANBA01000003_gene4740 1.18e-07 59.3 COG4653@1|root,COG4653@2|Bacteria,2I9AZ@201174|Actinobacteria 201174|Actinobacteria S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_75027_2 1232410.KI421417_gene2764 3.5e-22 99.4 2E91C@1|root,333AP@2|Bacteria,1NAQH@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_135738_1 1385658.U5KPZ6_9VIRU 7.31e-143 426.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_196707_1 1380347.JNII01000007_gene395 7.66e-10 64.7 COG2227@1|root,COG2227@2|Bacteria 2|Bacteria H 3-demethylubiquinone-9 3-O-methyltransferase activity - - - - - - - - - - - - MethyTransf_Reg,Methyltransf_13,Methyltransf_14,Methyltransf_23,Methyltransf_25,Methyltransf_31 k59_257343_2 856793.MICA_588 6.18e-36 139.0 COG0468@1|root,COG0468@2|Bacteria,1PK58@1224|Proteobacteria,2UB77@28211|Alphaproteobacteria 28211|Alphaproteobacteria L AAA domain - - - - - - - - - - - - AAA_24 k59_50818_1 1986029.Q9MBM3_9VIRU 8.04e-39 139.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_50818_3 105154.Q9MBU3_9VIRU 6.88e-18 86.3 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_50818_4 1385658.U5KPZ6_9VIRU 6.14e-223 632.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_50818_6 1385658.U5KNR1_9VIRU 5.69e-27 110.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_183704_2 1380894.S5TR92_9CIRC 3.48e-33 125.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_183704_3 1380894.S5TR92_9CIRC 5.13e-16 79.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_269409_5 742740.HMPREF9474_02314 1.28e-42 150.0 2A0KC@1|root,30NQJ@2|Bacteria,1V3K4@1239|Firmicutes,24HYK@186801|Clostridia,222N6@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_123955_1 1304872.JAGC01000009_gene780 1.27e-18 84.3 2C6KN@1|root,32Y69@2|Bacteria,1N8AV@1224|Proteobacteria,433PH@68525|delta/epsilon subdivisions,2WX67@28221|Deltaproteobacteria,2ME4E@213115|Desulfovibrionales 28221|Deltaproteobacteria S VRR_NUC - - - - - - - - - - - - VRR_NUC k59_378796_1 294631.Q5ZGG2_9CAUD 6.85e-47 171.0 4QFGZ@10239|Viruses,4QY9R@35237|dsDNA viruses no RNA stage,4QPY9@28883|Caudovirales,4QMRF@10699|Siphoviridae 10699|Siphoviridae S Phage terminase large subunit - - - - - - - - - - - - - k59_99974_1 570952.ATVH01000019_gene756 7.67e-24 103.0 COG1783@1|root,COG1783@2|Bacteria,1RAGC@1224|Proteobacteria,2U6JF@28211|Alphaproteobacteria,2JSIA@204441|Rhodospirillales 204441|Rhodospirillales S phage Terminase large subunit - - - - - - - - - - - - - k59_221946_3 1499680.CCFE01000031_gene3747 9.25e-17 79.0 292XD@1|root,2ZQEV@2|Bacteria,1V0SE@1239|Firmicutes,4HKHI@91061|Bacilli,1ZI63@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k59_197287_7 1068978.AMETH_6319 6.03e-13 76.3 COG3409@1|root,COG3409@2|Bacteria,2GRFR@201174|Actinobacteria,4EE9A@85010|Pseudonocardiales 201174|Actinobacteria M Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_1 k59_379471_3 1348662.CARG_02545 1.42e-07 60.8 COG0863@1|root,COG0863@2|Bacteria,2GU0U@201174|Actinobacteria,22PUX@1653|Corynebacteriaceae 201174|Actinobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_379471_4 765765.I3UMF8_9CAUD 4.21e-26 116.0 4QBY0@10239|Viruses,4QW35@35237|dsDNA viruses no RNA stage,4QQ4Q@28883|Caudovirales,4QNAU@10699|Siphoviridae 10699|Siphoviridae S UvrD-like helicase C-terminal domain - - - - - - - - - - - - - k59_75691_1 105154.Q9MBU6_9VIRU 8.32e-97 299.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_124668_3 1120956.JHZK01000002_gene902 0.000185 46.2 COG0745@1|root,COG0745@2|Bacteria,1Q6QE@1224|Proteobacteria,2VCTF@28211|Alphaproteobacteria,1JQE2@119043|Rhodobiaceae 28211|Alphaproteobacteria KT Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Trans_reg_C k59_124668_4 114615.BRADO6930 1.95e-10 61.6 2EHBB@1|root,33B36@2|Bacteria,1RGAQ@1224|Proteobacteria,2U70Q@28211|Alphaproteobacteria,3JZ8Y@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_124668_5 861208.AGROH133_06170 5.74e-55 188.0 COG3409@1|root,COG3772@1|root,COG3409@2|Bacteria,COG3772@2|Bacteria,1PSK5@1224|Proteobacteria,2U7GS@28211|Alphaproteobacteria,4BHG5@82115|Rhizobiaceae 28211|Alphaproteobacteria M Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - PG_binding_1,Phage_lysozyme k59_233720_1 1618251.A0A0C5I2L8_9CIRC 4.18e-35 136.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_367647_1 469660.A8HNV9_9CAUD 1.35e-11 72.4 4QBTM@10239|Viruses,4QWCV@35237|dsDNA viruses no RNA stage,4QRTG@28883|Caudovirales,4QNB6@10744|Podoviridae 10744|Podoviridae S Methyltransferase small domain - - - - - - - - - - - - - k59_3716_2 1692253.A0A0K1RLM4_9CIRC 3.49e-46 165.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_380179_4 1219035.NT2_13_00580 8.76e-58 193.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_355919_1 1385658.U5KPZ6_9VIRU 2.15e-77 248.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_295250_1 596153.Alide_3542 2.08e-37 148.0 2F07H@1|root,33TAZ@2|Bacteria,1NTT7@1224|Proteobacteria,2W1S2@28216|Betaproteobacteria,4AGRU@80864|Comamonadaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_64613_1 478749.BRYFOR_08569 2.41e-28 114.0 2A0KC@1|root,30NQJ@2|Bacteria,1V3K4@1239|Firmicutes,24HYK@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_234424_1 945021.TEH_08390 1.64e-06 50.8 COG3935@1|root,COG3935@2|Bacteria,1TPPF@1239|Firmicutes,4HNK6@91061|Bacilli 91061|Bacilli L Psort location Cytoplasmic, score - - - - - - - - - - - - DnaB_2,Phg_2220_C k59_76361_6 1234888.K0A2J2_9VIRU 9.53e-149 440.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_210557_1 420324.KI911970_gene1455 2.56e-53 176.0 2ATMD@1|root,31J5V@2|Bacteria,1RH31@1224|Proteobacteria,2UBNT@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tail tubular protein - - - - - - - - - - - - Tube k59_137564_2 1788447.A0A190WHJ9_9CIRC 1.15e-87 270.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_308095_1 4792.ETI31775 4.33e-105 332.0 2C7RP@1|root,2SPXE@2759|Eukaryota 2759|Eukaryota - - - - - - - - - - - - - - - k59_185055_1 438753.AZC_3583 7.89e-13 74.7 28IA2@1|root,2Z8CQ@2|Bacteria,1PQM2@1224|Proteobacteria,2TUAP@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_125982_1 1692253.A0A0K1RLM4_9CIRC 7.15e-16 84.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_344383_1 491915.Aflv_0673 3.41e-18 97.8 COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HAFE@91061|Bacilli,21W37@150247|Anoxybacillus 91061|Bacilli S Phage tail tape measure protein - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,SLT k59_15435_1 1618242.A0A0C5IBR9_9CIRC 6.98e-25 105.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_271356_3 948071.S4S2F7_9CAUD 7.47e-22 108.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_247084_1 1379725.S5TMY9_9CIRC 3.95e-13 72.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_15444_1 1280664.AUIX01000015_gene2196 5.02e-43 152.0 COG0535@1|root,COG0535@2|Bacteria,1UET7@1239|Firmicutes,24F49@186801|Clostridia,4C0TW@830|Butyrivibrio 186801|Clostridia S Iron-sulfur cluster-binding domain - - - - - - - - - - - - Fer4_12,Radical_SAM,SPASM k59_65222_1 145579.CAPSD_BPPHM 6.83e-114 351.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_65222_7 105154.Q9MBU6_9VIRU 1.58e-30 121.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_89363_1 1217705.F900_01855 2.1e-10 64.3 COG3179@1|root,COG3179@2|Bacteria,1R71F@1224|Proteobacteria,1RZTY@1236|Gammaproteobacteria,3NJ60@468|Moraxellaceae 1236|Gammaproteobacteria S Chitinase class I - - - - - - - - - - - - Glyco_hydro_19,PG_binding_1 k59_4443_1 1492922.GY26_16080 1.45e-79 257.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1RP8Z@1236|Gammaproteobacteria,1J8Y8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_101578_1 186617.M9M8L2_9VIRU 7e-32 133.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_113407_1 525246.HMPREF0058_0733 1.09e-47 182.0 COG0749@1|root,COG0749@2|Bacteria,2IG0A@201174|Actinobacteria,4D4MC@85005|Actinomycetales 201174|Actinobacteria L DNA polymerase - - - - - - - - - - - - DNA_pol_A k59_126559_1 1219035.NT2_13_00580 4.2e-68 228.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_333018_4 260827.Q6R6B4_9CAUD 9.63e-65 219.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales,4QNDH@10744|Podoviridae 10744|Podoviridae S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_175130_1 428125.CLOLEP_01425 5.38e-52 177.0 292XD@1|root,2ZQEV@2|Bacteria,1V48I@1239|Firmicutes,24GZD@186801|Clostridia,3WNVV@541000|Ruminococcaceae 186801|Clostridia S COG NOG18825 non supervised orthologous group - - - - - - - - - - - - - k59_16001_2 1498011.A0A096XUV1_9CAUD 2.25e-19 85.9 4QAZF@10239|Viruses,4QPH6@28883|Caudovirales 28883|Caudovirales S Protein of unknwon function (DUF3310) - - - - - - - - - - - - - k59_16001_5 948071.S4S2D9_9CAUD 4.26e-112 344.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae 10744|Podoviridae S ribonucleoside-triphosphate reductase activity - - - - - - - - - - - - - k59_321090_5 1618242.A0A0C5IBR9_9CIRC 5.25e-27 116.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_40994_1 398578.Daci_1943 2.54e-97 316.0 COG3064@1|root,COG3064@2|Bacteria,1R6JV@1224|Proteobacteria 1224|Proteobacteria M Membrane - - - - - - - - - - - - - k59_162886_2 1234888.K0A2J2_9VIRU 1.35e-54 189.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_53385_2 1122135.KB893169_gene2483 3.91e-27 106.0 COG0741@1|root,COG0741@2|Bacteria,1N1XZ@1224|Proteobacteria,2UB2Y@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Transglycosylase SLT domain - - - - - - - - - - - - SLT k59_199204_2 1265756.AWZW01000008_gene1118 3.41e-16 77.8 2AN8I@1|root,31D6K@2|Bacteria,1P458@1224|Proteobacteria,2UWQ2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_199204_3 935261.JAGL01000009_gene1165 3.09e-34 130.0 COG0209@1|root,COG0209@2|Bacteria,1PM78@1224|Proteobacteria,2UZUM@28211|Alphaproteobacteria,43QGW@69277|Phyllobacteriaceae 28211|Alphaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - - - - - - - - - - - - k59_211981_2 1560342.A0A0A0RLW6_9CAUD 5.2e-35 142.0 4QAR1@10239|Viruses,4QPJE@28883|Caudovirales,4QJ64@10662|Myoviridae 10662|Myoviridae S ATPase activity - - - - - - - - - - - - - k59_102243_1 1234888.K0A2J2_9VIRU 1.29e-84 267.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_235599_3 1122963.AUHB01000026_gene1117 1.72e-07 57.8 2DBI5@1|root,2Z9EN@2|Bacteria,1PMHG@1224|Proteobacteria 1224|Proteobacteria L PDDEXK-like domain of unknown function (DUF3799) - - - ko:K10906 - - - - ko00000,ko01000,ko03400 - - - DUF3799 k59_53474_1 1150626.PHAMO_30123 9.19e-06 47.4 2E5X1@1|root,330KZ@2|Bacteria,1N8Z4@1224|Proteobacteria,2UF7M@28211|Alphaproteobacteria,2JU50@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_53474_2 1054213.HMPREF9946_00294 5.56e-06 48.9 28RDB@1|root,2ZDSP@2|Bacteria,1RBF9@1224|Proteobacteria,2U586@28211|Alphaproteobacteria,2JRSR@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - Tube k59_139215_1 1382306.JNIM01000001_gene1971 2.21e-05 45.8 COG2120@1|root,COG2120@2|Bacteria 2|Bacteria S N-acetylglucosaminylinositol deacetylase activity - - - - - - - - - - - - PIG-L k59_139215_2 456320.Mvol_0245 1.85e-37 141.0 COG3919@1|root,arCOG06897@2157|Archaea 2157|Archaea S COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ) - - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_3,ATPgrasp_Ter k59_30306_1 1121378.KB899701_gene2068 5.74e-09 56.6 2EH5P@1|root,33AXK@2|Bacteria 2|Bacteria S Bacteriophage HK97-gp10, putative tail-component - - - - - - - - - - - - HK97-gp10_like k59_54219_1 279714.FuraDRAFT_0273 1.39e-50 181.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2VJKE@28216|Betaproteobacteria,2KQ0H@206351|Neisseriales 206351|Neisseriales S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_151518_1 1009370.ALO_12301 1.36e-15 89.7 COG0553@1|root,COG0827@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,1VMRR@1239|Firmicutes,4H73C@909932|Negativicutes 909932|Negativicutes L Type III restriction enzyme, res subunit - - - - - - - - - - - - ResIII k59_41966_1 428125.CLOLEP_01379 4.14e-67 218.0 COG0553@1|root,COG0553@2|Bacteria,1TS9W@1239|Firmicutes,24CGX@186801|Clostridia,3WN6X@541000|Ruminococcaceae 186801|Clostridia KL Helicase conserved C-terminal domain - - - - - - - - - - - - - k59_309586_1 935261.JAGL01000016_gene2794 2.26e-30 125.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2TSF9@28211|Alphaproteobacteria,43I71@69277|Phyllobacteriaceae 28211|Alphaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_321915_2 1417599.U6C6Z0_9CAUD 4.5e-22 95.5 4QB55@10239|Viruses,4QW4S@35237|dsDNA viruses no RNA stage,4QSJ0@28883|Caudovirales,4QNGX@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_272973_1 204669.Acid345_3174 3.44e-29 120.0 COG5511@1|root,COG5511@2|Bacteria,3Y69V@57723|Acidobacteria,2JKEE@204432|Acidobacteriia 204432|Acidobacteriia S Phage portal protein, lambda family - - - - - - - - - - - - Phage_portal_2 k59_297541_1 990285.RGCCGE502_22705 1.21e-05 52.0 COG5283@1|root,COG5283@2|Bacteria,1NFKU@1224|Proteobacteria,2U1H4@28211|Alphaproteobacteria,4BCD7@82115|Rhizobiaceae 28211|Alphaproteobacteria S Phage-related minor tail protein - - - - - - - - - - - - Peptidase_M15_3,PhageMin_Tail k59_213681_1 1210884.HG799467_gene13131 1.3e-117 355.0 COG0553@1|root,COG0553@2|Bacteria 2|Bacteria L helicase activity - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_261010_1 1089548.KI783301_gene2629 7.46e-20 88.2 COG0863@1|root,COG0863@2|Bacteria,1UZIN@1239|Firmicutes,4HU16@91061|Bacilli 91061|Bacilli L DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_261010_2 1111454.HMPREF1250_1035 5.23e-32 124.0 COG0553@1|root,COG0553@2|Bacteria,1TP2C@1239|Firmicutes,4H2V4@909932|Negativicutes 909932|Negativicutes KL DEAD-like helicases superfamily - - - - - - - - - - - - N6_N4_Mtase k59_79328_2 1176422.I6S6Y5_9CAUD 4.66e-25 108.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - GO:0008150,GO:0044403,GO:0044409,GO:0044411,GO:0044419,GO:0051701,GO:0051704,GO:0051828,GO:0051830,GO:0085027 - - - - - - - - - - - k59_164454_2 1197951.I6S2A9_9CAUD 1.54e-161 476.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales 28883|Caudovirales S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_103625_1 1122201.AUAZ01000017_gene2947 9.26e-69 234.0 COG0749@1|root,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,465DD@72275|Alteromonadaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - - - - - - - - - - - DNA_pol_A k59_103625_2 10752.A0MZC9_BPN4 6.56e-49 180.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_310304_1 2003327.REP_BPCHP 1.63e-07 60.1 4QCVK@10239|Viruses,4QUMV@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_249286_2 194802.Q8LT46_9CAUD 0.000123 47.0 4QE6E@10239|Viruses,4QV23@35237|dsDNA viruses no RNA stage,4QTFG@28883|Caudovirales 28883|Caudovirales S protein dimerization activity - - - - - - - - - - - - - k59_370497_1 1028800.RG540_CH13830 3.51e-53 178.0 2DUXE@1|root,312CE@2|Bacteria,1PQIE@1224|Proteobacteria,2V2XC@28211|Alphaproteobacteria,4BJT8@82115|Rhizobiaceae 28211|Alphaproteobacteria S Phage T7 capsid assembly protein - - - - - - - - - - - - Phage_T7_Capsid k59_17405_1 691965.D4P7C3_9CAUD 3.18e-33 119.0 4QDCX@10239|Viruses,4R0GS@35237|dsDNA viruses no RNA stage,4QS3P@28883|Caudovirales,4QKU8@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_17405_2 691965.D4P7C0_9CAUD 3.96e-58 183.0 4QDUR@10239|Viruses,4QVMY@35237|dsDNA viruses no RNA stage,4QU8R@28883|Caudovirales,4QKNQ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_17405_3 691965.D4P7B9_9CAUD 9.52e-28 105.0 4QFDH@10239|Viruses,4QWV5@35237|dsDNA viruses no RNA stage,4QPB8@28883|Caudovirales,4QKNN@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_186435_3 925984.E5AGG0_9CAUD 1.19e-27 103.0 4QD1J@10239|Viruses,4QW7G@35237|dsDNA viruses no RNA stage,4QQDR@28883|Caudovirales,4QI14@10662|Myoviridae 10662|Myoviridae S Protein of unknown function (DUF1364) - - - - - - - - - - - - - k59_186435_7 180332.JTGN01000026_gene1584 8.54e-05 51.2 COG1196@1|root,COG1572@1|root,COG3209@1|root,COG3210@1|root,COG5434@1|root,COG1196@2|Bacteria,COG1572@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG5434@2|Bacteria 2|Bacteria M polygalacturonase activity - - 3.2.1.97 ko:K02004,ko:K17624,ko:K20951,ko:K20952,ko:K21493 ko05111,map05111 M00258 - - ko00000,ko00001,ko00002,ko01000,ko02000,ko02048 3.A.1 GH101 - F5_F8_type_C,FIVAR,Glyco_hydro_28,LRR_5,Laminin_G_3 k59_176828_1 1125863.JAFN01000001_gene3537 1.66e-52 178.0 28WDW@1|root,2ZIE6@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_176829_1 1609634.A0A0C5AFV4_9VIRU 1.52e-67 223.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_176913_1 2003327.CAPSD_BPCHP 4.79e-29 122.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_7329_1 1302286.BAOT01000027_gene1327 9.04e-25 108.0 COG0209@1|root,COG0209@2|Bacteria,1TT3U@1239|Firmicutes,4HFF1@91061|Bacilli,3F3VU@33958|Lactobacillaceae 91061|Bacilli F ribonucleoside-triphosphate reductase activity rtpR - 1.17.4.2 ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02014,R02020,R02022,R02023,R04315 RC00013,RC00613 ko00000,ko00001,ko00002,ko01000 - - - Ribonuc_red_lgC k59_165228_1 1986029.Q9MBM3_9VIRU 4.46e-42 151.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_165228_3 1385658.U5KPZ6_9VIRU 1.31e-37 139.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_226531_1 1096930.L284_17065 7.65e-88 285.0 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,2TVEI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA polymerase family A - - - - - - - - - - - - DNA_pol_A k59_383339_1 352165.HMPREF7215_0583 2.82e-25 112.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,3T9XW@508458|Synergistetes 508458|Synergistetes L DNA polymerase I polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A k59_7433_1 1415780.JPOG01000001_gene1751 2.74e-25 111.0 291GM@1|root,2ZP3A@2|Bacteria,1RD1E@1224|Proteobacteria,1S4X6@1236|Gammaproteobacteria,1X9SN@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k59_68453_1 2342.SOPEG_1868 2.15e-14 71.6 COG5164@1|root,COG5164@2|Bacteria,1N5J8@1224|Proteobacteria,1SAJD@1236|Gammaproteobacteria 1224|Proteobacteria K regulation of DNA-templated transcription, elongation - - - - - - - - - - - - - k59_383491_1 272568.GDI3670 3.94e-27 114.0 COG0234@1|root,COG0234@2|Bacteria,1NJKP@1224|Proteobacteria,2UM25@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter - - - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - - k59_141063_1 421531.IX38_09265 7.49e-05 50.8 COG0657@1|root,COG0657@2|Bacteria,4NIQ0@976|Bacteroidetes,1I4XI@117743|Flavobacteriia,3ZPUW@59732|Chryseobacterium 976|Bacteroidetes I Carboxylesterase family - - - - - - - - - - - - Abhydrolase_3,Peptidase_S9 k59_371489_1 1380355.JNIJ01000008_gene1966 2.25e-50 168.0 COG1442@1|root,COG1442@2|Bacteria,1QH4S@1224|Proteobacteria,2U2NZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria M glycosyl transferase family 8 - - - - - - - - - - - - - k59_31987_1 1692248.A0A0K1RLN2_9CIRC 8.1e-36 131.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_359975_12 5671.XP_001468508.1 1.56e-21 105.0 COG0749@1|root,KOG0950@2759|Eukaryota,3XSG4@5653|Kinetoplastida 5653|Kinetoplastida H Mitochondrial DNA polymerase I protein A POL1A - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_pol_A k59_324541_2 691965.D4P7I3_9CAUD 5.4e-257 749.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_117051_1 794903.OPIT5_06130 3.34e-50 172.0 COG0270@1|root,COG0270@2|Bacteria 2|Bacteria L DNA (cytosine-5-)-methyltransferase activity ydiP - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_227403_2 644282.Deba_1727 1.3e-21 98.6 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2WJCA@28221|Deltaproteobacteria 28221|Deltaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_44478_4 1622193.A0A0E3XA19_9CAUD 1.47e-21 91.3 4QAU9@10239|Viruses,4QQV4@28883|Caudovirales,4QKUJ@10699|Siphoviridae 10699|Siphoviridae S Single-strand binding protein family - - - - - - - - - - - - - k59_384242_2 545693.BMQ_5109 9.3e-05 43.5 COG1551@1|root,COG1551@2|Bacteria,1VEEF@1239|Firmicutes,4HNPJ@91061|Bacilli,1ZJ2S@1386|Bacillus 91061|Bacilli T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding csrA - - ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 - - - ko00000,ko00001,ko03019 - - - CsrA k59_202559_1 1305732.JAGG01000001_gene1901 1.13e-31 123.0 COG0463@1|root,COG0463@2|Bacteria,2IB0Y@201174|Actinobacteria,4FNC2@85023|Microbacteriaceae 201174|Actinobacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_4 k59_141819_1 490913.C4NTE4_9CAUD 4.82e-60 205.0 4QBYE@10239|Viruses,4QVYH@35237|dsDNA viruses no RNA stage,4QQTP@28883|Caudovirales,4QP46@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_359986_2 1177928.TH2_09534 1.11e-44 154.0 28HS3@1|root,2Z7ZE@2|Bacteria,1QH9A@1224|Proteobacteria,2TVB0@28211|Alphaproteobacteria,2JPPD@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_187618_1 933262.AXAM01000022_gene3212 4.34e-06 55.5 COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,42PA8@68525|delta/epsilon subdivisions,2X7NH@28221|Deltaproteobacteria 28221|Deltaproteobacteria L DNA methylase - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_227410_2 1327036.R4JHP8_9CAUD 6.98e-20 94.0 4QCEF@10239|Viruses,4QVWZ@35237|dsDNA viruses no RNA stage,4QTBA@28883|Caudovirales,4QMGR@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_117070_2 768710.DesyoDRAFT_5152 1.21e-08 60.5 2DT4K@1|root,33INK@2|Bacteria,1VQEE@1239|Firmicutes,253M4@186801|Clostridia 1239|Firmicutes - - - - - - - - - - - - - - - k59_215550_1 204669.Acid345_4387 1.78e-05 55.5 COG3420@1|root,COG3420@2|Bacteria,3Y6PA@57723|Acidobacteria,2JMNE@204432|Acidobacteriia 204432|Acidobacteriia P Parallel beta-helix repeats - - - - - - - - - - - - Beta_helix k59_202663_1 1622193.A0A0E3XB61_9CAUD 2.11e-08 60.8 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_360108_1 1329516.JPST01000005_gene1303 4.78e-34 127.0 COG0863@1|root,COG0863@2|Bacteria,1UWKM@1239|Firmicutes,4IC4N@91061|Bacilli,27D8U@186824|Thermoactinomycetaceae 91061|Bacilli L DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_34002_2 1548905.A0A0A1IVS4_9CAUD 2.71e-53 184.0 4QH9I@10239|Viruses,4QTW6@28883|Caudovirales,4QMZW@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_188530_1 1453503.AU05_17305 3.71e-29 127.0 2E983@1|root,333GI@2|Bacteria,1N8C3@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_325836_1 857087.Metme_2336 1.76e-109 330.0 2CI0W@1|root,2Z81W@2|Bacteria,1R9FZ@1224|Proteobacteria,1S0NA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage X family - - - - - - - - - - - - Phage_CRI,Phage_X k59_290511_1 1391025.T1YRV6_9VIRU 1.57e-12 71.2 4QHM9@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_290511_2 1634486.A0A0E3M1X5_9VIRU 6.77e-36 138.0 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_9185_3 1002672.SAR11G3_01288 1.75e-60 191.0 2AV7S@1|root,31KYE@2|Bacteria,1RKQ6@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_9185_7 1122599.AUGR01000001_gene288 3.55e-09 56.6 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,1SQ0T@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_70412_1 1548151.LS70_02045 4.35e-06 46.6 COG1551@1|root,COG1551@2|Bacteria,1Q4KC@1224|Proteobacteria,42W0C@68525|delta/epsilon subdivisions,2YQ7K@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria J Belongs to the CsrA family csrA - - ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 - - - ko00000,ko00001,ko03019 - - - CsrA k59_385435_1 1123499.KB908022_gene1048 0.000433 46.2 COG1442@1|root,COG1442@2|Bacteria,1NJ1J@1224|Proteobacteria,2VK7G@28216|Betaproteobacteria,2KSPD@206351|Neisseriales 206351|Neisseriales M glycosyl transferase family 8 - - - - - - - - - - - - - k59_131381_1 428125.CLOLEP_01409 1.82e-72 234.0 COG4626@1|root,COG4626@2|Bacteria,1TT9I@1239|Firmicutes,24AFK@186801|Clostridia,3WNF4@541000|Ruminococcaceae 186801|Clostridia S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_45898_1 1123288.SOV_4c02780 2.05e-75 259.0 COG0503@1|root,COG0553@1|root,COG2263@1|root,COG3846@1|root,COG0503@2|Bacteria,COG0553@2|Bacteria,COG2263@2|Bacteria,COG3846@2|Bacteria,1TSYQ@1239|Firmicutes,4H5A6@909932|Negativicutes 909932|Negativicutes F protein secretion by the type IV secretion system - - - - - - - - - - - - SLT k59_325936_2 937777.Deipe_2101 5.33e-44 149.0 2BYEQ@1|root,32SXE@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_82543_1 445971.ANASTE_00711 9.27e-08 62.0 COG1783@1|root,COG1783@2|Bacteria,1TRQP@1239|Firmicutes,248E9@186801|Clostridia,25YQA@186806|Eubacteriaceae 186801|Clostridia S Phage terminase, large subunit, PBSX family - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_143204_1 697281.Mahau_0365 0.000176 44.3 COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,24HHC@186801|Clostridia,42GBY@68295|Thermoanaerobacterales 186801|Clostridia F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk - 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Thymidylate_kin k59_144355_1 1126411.I1TEL3_9CIRC 8.06e-14 75.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_21342_1 927704.SELR_23640 1.95e-45 164.0 COG0535@1|root,COG0535@2|Bacteria,1VSG9@1239|Firmicutes 1239|Firmicutes S radical SAM domain protein - - - - - - - - - - - - - k59_241080_3 1120971.AUCA01000053_gene371 3.9e-19 85.5 COG0863@1|root,COG0863@2|Bacteria,1UZIN@1239|Firmicutes,4HU16@91061|Bacilli 91061|Bacilli L DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_204932_1 1385658.U5KPZ6_9VIRU 1.97e-80 257.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_265109_3 272560.BPSS1438 8.32e-12 67.4 COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,2VJNV@28216|Betaproteobacteria,1K2NV@119060|Burkholderiaceae 28216|Betaproteobacteria M Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8 k59_362133_1 1121441.AUCX01000016_gene2326 5.09e-39 145.0 COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,42N4A@68525|delta/epsilon subdivisions,2WMCH@28221|Deltaproteobacteria,2M9HC@213115|Desulfovibrionales 28221|Deltaproteobacteria M PFAM UDP-N-acetylglucosamine 2-epimerase - - 3.2.1.183,5.1.3.14 ko:K01791,ko:K08068 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase_2 k59_327108_1 1481112.A0A023W4N6_9CAUD 1.16e-18 86.3 4QASV@10239|Viruses,4QWD9@35237|dsDNA viruses no RNA stage,4QQ4N@28883|Caudovirales,4QIBN@10662|Myoviridae 10662|Myoviridae S recA bacterial DNA recombination protein - - - - - - - - - - - - - k59_218226_1 1618248.A0A0C5IB82_9CIRC 8.17e-51 174.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_339078_4 105154.Q9MBU6_9VIRU 1.07e-163 483.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_96684_1 105154.Q9MBU6_9VIRU 6.88e-86 270.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_59112_1 1149133.ppKF707_0770 8.85e-26 110.0 COG0740@1|root,COG0740@2|Bacteria,1MUQ9@1224|Proteobacteria,1RYWV@1236|Gammaproteobacteria,1YIT5@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria OU Clp protease - - - - - - - - - - - - CLP_protease k59_168317_2 1121363.KB902191_gene233 1.5e-12 73.6 COG1475@1|root,COG1475@2|Bacteria,2H100@201174|Actinobacteria 201174|Actinobacteria K ParB-like nuclease domain - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_169064_1 1096546.WYO_0201 9.14e-99 315.0 28P6A@1|root,2ZC10@2|Bacteria,1RBZE@1224|Proteobacteria,2UQEG@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_169064_4 768066.HELO_2643 1.6e-51 179.0 28JC4@1|root,2Z96S@2|Bacteria,1RI8W@1224|Proteobacteria,1S6FI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S P22 coat protein-protein 5 domain protein - - - - - - - - - - - - - k59_169064_7 1204524.K4HY20_9CAUD 1.54e-15 76.6 4QHN2@10239|Viruses,4QVFE@35237|dsDNA viruses no RNA stage,4QTI8@28883|Caudovirales,4QMAV@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_120215_2 1530186.JQEY01000026_gene1786 2.28e-18 84.7 COG2369@1|root,COG2369@2|Bacteria,1PERP@1224|Proteobacteria,2UJA0@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage Mu protein F like protein - - - - - - - - - - - - Phage_Mu_F k59_145366_1 105154.Q9MBU3_9VIRU 4.07e-17 83.2 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_145366_3 115711.CP_0543 5.23e-15 76.3 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_145366_4 105154.Q9MBT9_9VIRU 2.9e-16 73.9 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_145366_5 1385658.U5KPZ6_9VIRU 5.17e-209 598.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_265932_1 411460.RUMTOR_02036 3.21e-156 482.0 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_351747_2 1279015.KB908467_gene500 3.68e-08 58.5 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1Y3QX@135624|Aeromonadales 135624|Aeromonadales K Belongs to the ParB family - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_351749_1 1122132.AQYH01000015_gene2287 2.68e-17 86.3 COG1408@1|root,COG1408@2|Bacteria,1NUS0@1224|Proteobacteria,2UR92@28211|Alphaproteobacteria 28211|Alphaproteobacteria S metallophosphoesterase - - - - - - - - - - - - - k59_170102_3 870967.VIS19158_03906 1.19e-10 63.2 2DMPB@1|root,32SV8@2|Bacteria,1NHUE@1224|Proteobacteria,1SIKI@1236|Gammaproteobacteria,1XY3E@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k59_364161_25 266834.SMc04187 2.48e-70 239.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,2U1P9@28211|Alphaproteobacteria,4BDQ9@82115|Rhizobiaceae 28211|Alphaproteobacteria S DNA packaging protein gp2 - - - - - - - - - - - - Terminase_6,Terminase_6C k59_364161_36 95619.PM1_0217520 2.93e-15 76.6 COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria 1224|Proteobacteria KT HNH endonuclease - - - - - - - - - - - - HNH_3 k59_364161_40 666685.R2APBS1_1628 9.17e-41 166.0 COG3598@1|root,COG3598@2|Bacteria 2|Bacteria L Psort location Cytoplasmic, score - - - - - - - - - - - - AAA_25,DUF927,HTH_23,Prim-Pol,RepB_primase k59_364161_42 317936.Nos7107_2419 9.24e-23 95.5 COG0338@1|root,COG0338@2|Bacteria,1G5RN@1117|Cyanobacteria,1HN98@1161|Nostocales 1117|Cyanobacteria L D12 class N6 adenine-specific DNA methyltransferase - - - - - - - - - - - - - k59_364161_43 1122243.KB903771_gene1522 2.44e-11 66.6 2C6KN@1|root,32Y69@2|Bacteria,1N8AV@1224|Proteobacteria,1SFCN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S VRR-NUC domain - - - - - - - - - - - - VRR_NUC k59_364161_49 329254.Q2NPG0_9CAUD 6.48e-32 121.0 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QKM7@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k59_266994_1 366394.Smed_1830 2.47e-10 66.6 28PTM@1|root,2ZCIH@2|Bacteria,1RBCN@1224|Proteobacteria,2VGPG@28211|Alphaproteobacteria,4BDH5@82115|Rhizobiaceae 28211|Alphaproteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_191173_2 1609634.A0A0C5AFV4_9VIRU 8.73e-69 230.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_243623_1 1156919.QWC_12603 2.22e-12 70.9 COG0741@1|root,COG0741@2|Bacteria,1N5XK@1224|Proteobacteria 1224|Proteobacteria M lytic transglycosylase activity - - - ko:K02395 - - - - ko00000,ko02035 - - - - k59_292421_1 1385658.U5KPZ6_9VIRU 9.87e-27 109.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_292421_3 1165094.RINTHH_3920 4.7e-51 176.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_353292_1 105154.Q9MBU6_9VIRU 8.28e-122 369.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_24992_1 573174.M4MA32_9VIRU 2.4e-60 203.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage 10239|Viruses S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_24992_2 1218084.BBJK01000077_gene5333 1.43e-37 150.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2VP7E@28216|Betaproteobacteria,1KFK1@119060|Burkholderiaceae 28216|Betaproteobacteria S Phage portal protein - - - - - - - - - - - - Phage_portal k59_24992_3 573174.M4MBI0_9VIRU 2.29e-231 659.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage 10239|Viruses S Phage Terminase - - - - - - - - - - - - - k59_73751_1 246197.MXAN_1209 4.8e-21 100.0 COG5545@1|root,COG5545@2|Bacteria,1MVGK@1224|Proteobacteria 1224|Proteobacteria D virulence-associated E family protein - - - ko:K06919 - - - - ko00000 - - - PriCT_2,Prim-Pol,Toprim_3,VirE k59_292423_1 1219049.SP5_069_01280 1.79e-65 209.0 2DRE2@1|root,33BCC@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_61702_1 1220601.L7TLX3_9CAUD 1.58e-118 358.0 4QF7H@10239|Viruses,4R06M@35237|dsDNA viruses no RNA stage,4QQTS@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_328927_1 1237149.C900_04204 9.56e-16 90.5 COG3291@1|root,COG4099@1|root,COG4932@1|root,COG3291@2|Bacteria,COG4099@2|Bacteria,COG4932@2|Bacteria,4NP7H@976|Bacteroidetes,47XCB@768503|Cytophagia 976|Bacteroidetes M Immunoglobulin like - - - - - - - - - - - - - k59_365129_1 59538.XP_005976423.1 5.24e-51 176.0 COG0629@1|root,COG1252@1|root,KOG1653@2759|Eukaryota,KOG2495@2759|Eukaryota,3A4A4@33154|Opisthokonta,3BPVJ@33208|Metazoa,3D6VW@33213|Bilateria 33208|Metazoa L single-stranded DNA binding - - - - - - - - - - - - SSB k59_365129_2 196490.AUEZ01000004_gene3956 7.82e-48 160.0 2A4D4@1|root,30SYX@2|Bacteria,1PCIM@1224|Proteobacteria,2USSQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_365129_3 1353531.AZNX01000020_gene4385 7.41e-55 178.0 COG1738@1|root,COG1738@2|Bacteria,1RDSF@1224|Proteobacteria 1224|Proteobacteria S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage - - - ko:K09125 - - - - ko00000 - - - Vut_1 k59_122324_1 1788438.A0A190WHE1_9CIRC 2.92e-06 55.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_49470_2 1609634.A0A0C5AFV4_9VIRU 2.6e-61 206.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_292487_1 935565.JAEM01000006_gene3917 5.13e-18 84.0 2E03M@1|root,32VSF@2|Bacteria,1N1I1@1224|Proteobacteria,2UN7W@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_231695_1 1463934.JOCF01000064_gene4216 9.09e-41 143.0 COG0270@1|root,COG0270@2|Bacteria,2GNB2@201174|Actinobacteria 201174|Actinobacteria L DNA (cytosine-5-)-methyltransferase activity - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_317350_1 1385658.U5KNR1_9VIRU 7.3e-74 236.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_159417_2 1692244.A0A0K1RLR5_9CIRC 7.33e-105 312.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_220358_1 285514.JNWO01000004_gene6414 2.46e-12 75.1 2C0VQ@1|root,33I0S@2|Bacteria,2IAD1@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_268686_1 1609634.A0A0C5AFV4_9VIRU 9.68e-49 172.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_195774_2 948071.S4S2E3_9CAUD 6.91e-25 99.4 4QGDB@10239|Viruses,4QZHU@35237|dsDNA viruses no RNA stage,4QSG0@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_37840_1 76114.ebA7094 4.15e-08 60.8 COG1793@1|root,COG1793@2|Bacteria,1MUW3@1224|Proteobacteria,2VI3P@28216|Betaproteobacteria,2KUKX@206389|Rhodocyclales 206389|Rhodocyclales L DNA ligase dnaL - 6.5.1.1,6.5.1.6,6.5.1.7 ko:K10747 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00381,R00382,R10822,R10823 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_ligase_A_M,DNA_ligase_OB_2 k59_293108_6 1385658.U5KPZ6_9VIRU 9.98e-130 395.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_110816_1 1165094.RINTHH_3920 5.41e-75 238.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_329509_4 525256.HMPREF0091_11228 2.1e-08 57.8 COG1403@1|root,COG1403@2|Bacteria,2IJEJ@201174|Actinobacteria 201174|Actinobacteria L HNH endonuclease - - - ko:K07451 - - - - ko00000,ko01000,ko02048 - - - HNH k59_98585_2 1618248.A0A0C5IB82_9CIRC 8.84e-15 82.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_220370_1 279383.Q5DN91_9CAUD 1.54e-82 264.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_110818_1 691965.D4P7L7_9CAUD 3.15e-28 115.0 4QB9J@10239|Viruses,4QXFE@35237|dsDNA viruses no RNA stage,4QS1Z@28883|Caudovirales,4QN8F@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_134886_1 1234888.K0A2J2_9VIRU 5.8e-92 290.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_293116_1 1297863.APJF01000020_gene2704 1.58e-12 73.6 28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TURR@28211|Alphaproteobacteria,3JUCC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_281365_1 1120977.JHUX01000003_gene1143 3.23e-18 96.7 COG0507@1|root,COG1372@1|root,COG0507@2|Bacteria,COG1372@2|Bacteria,1R1AT@1224|Proteobacteria,1RZWT@1236|Gammaproteobacteria,3NKPB@468|Moraxellaceae 1236|Gammaproteobacteria L Participates in initiation and elongation during chromosome replication - - - - - - - - - - - - Hom_end_hint k59_282197_1 1449355.JQNR01000006_gene2143 8.54e-05 51.2 2D784@1|root,32TNH@2|Bacteria,2GRDQ@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_123768_3 561231.Pecwa_1656 1.03e-12 72.0 COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,1RPSH@1236|Gammaproteobacteria,1MT52@122277|Pectobacterium 1236|Gammaproteobacteria H C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase,Dam,MethyltransfD12 k59_50681_1 1120963.KB894518_gene2798 6.11e-20 94.4 COG2887@1|root,COG2887@2|Bacteria,1QEBA@1224|Proteobacteria,1RSK2@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_366297_2 645099.MREP_BBTVA 1.33e-08 63.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_293760_1 1609634.A0A0C5AFV4_9VIRU 5.8e-80 259.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_318262_2 765910.MARPU_09550 1.4e-23 105.0 COG4653@1|root,COG4653@2|Bacteria,1MWMB@1224|Proteobacteria,1S4MJ@1236|Gammaproteobacteria,1X0RU@135613|Chromatiales 135613|Chromatiales S Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_111396_1 1538804.A0A088FAR2_9CAUD 6.43e-35 147.0 4QAQ9@10239|Viruses,4QPTV@28883|Caudovirales,4QKRS@10699|Siphoviridae 10699|Siphoviridae S Putative phage tail protein - GO:0005575,GO:0008150,GO:0016032,GO:0018995,GO:0019012,GO:0019058,GO:0019062,GO:0022610,GO:0030430,GO:0033643,GO:0033646,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044403,GO:0044406,GO:0044419,GO:0044650,GO:0051704 - - - - - - - - - - - k59_50686_1 744980.TRICHSKD4_6171 3.6e-82 250.0 COG1961@1|root,COG1961@2|Bacteria,1MXXT@1224|Proteobacteria,2U9WZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Site-specific recombinases, DNA invertase Pin homologs - - - ko:K14060 - - - - ko00000 - - - Resolvase k59_135564_5 1676184.A0A186YBN5_9CIRC 8.2e-33 130.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_99226_3 1609634.A0A0C5AFT2_9VIRU 8.31e-36 137.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_26220_1 742740.HMPREF9474_02303 1.11e-13 70.5 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia,221YV@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_318265_1 386043.lwe1578 9.33e-16 87.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,26J7D@186820|Listeriaceae 91061|Bacilli L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A k59_99231_2 153948.NAL212_2341 3.57e-05 45.1 2E7GT@1|root,331ZH@2|Bacteria,1NAHD@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_366364_2 56780.SYN_00585 3.65e-94 287.0 COG0451@1|root,COG0451@2|Bacteria,1MUGT@1224|Proteobacteria,42M12@68525|delta/epsilon subdivisions,2WIJX@28221|Deltaproteobacteria,2MQ3S@213462|Syntrophobacterales 28221|Deltaproteobacteria GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction fcl - 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R05692 RC01014 ko00000,ko00001,ko01000 - - iAF987.Gmet_1312 Epimerase k59_355005_1 929712.KI912613_gene4087 2.35e-46 171.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,2IEA1@201174|Actinobacteria 201174|Actinobacteria S TIGRFAM Phage - - - - - - - - - - - - Terminase_6,Terminase_6C k59_148213_2 1439940.BAY1663_02360 1.43e-35 140.0 28JTG@1|root,2Z9IR@2|Bacteria,1PCXZ@1224|Proteobacteria,1SIJB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_148213_3 1429912.V5R9A1_9CAUD 1.33e-07 59.3 4QB4T@10239|Viruses,4QYFG@35237|dsDNA viruses no RNA stage,4QR7K@28883|Caudovirales,4QN2T@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_245393_3 630626.EBL_c21840 1.3e-30 117.0 2D0K9@1|root,32T8S@2|Bacteria,1MZRW@1224|Proteobacteria,1SF0N@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_26905_1 1609634.A0A0C5ANA6_9VIRU 7.12e-19 87.4 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_209588_1 655097.C8ZKI1_9CAUD 1.64e-56 201.0 4QF3C@10239|Viruses,4QWIA@35237|dsDNA viruses no RNA stage,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_197181_11 1121441.AUCX01000031_gene1701 2.51e-08 53.1 2AFF0@1|root,315F0@2|Bacteria,1RHGE@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_366876_2 1211115.ALIQ01000188_gene655 2.78e-101 326.0 28MS5@1|root,2ZB0J@2|Bacteria,1PTV9@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_136289_1 1266908.AQPB01000051_gene2466 4.19e-27 115.0 COG4653@1|root,COG4653@2|Bacteria,1MWMB@1224|Proteobacteria,1S4MJ@1236|Gammaproteobacteria,1X0RU@135613|Chromatiales 135613|Chromatiales S Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_136289_7 272942.RCAP_rcc00971 6.06e-66 216.0 28M7D@1|root,2ZAKV@2|Bacteria,1R6BC@1224|Proteobacteria,2U3UN@28211|Alphaproteobacteria,1FCRU@1060|Rhodobacter 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_136289_10 1517681.HW45_02700 7.8e-43 176.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1QZAD@1224|Proteobacteria,1RYP3@1236|Gammaproteobacteria 1236|Gammaproteobacteria D nuclear chromosome segregation - - - - - - - - - - - - - k59_136289_13 1121935.AQXX01000130_gene2403 1.24e-12 82.0 COG4733@1|root,COG4733@2|Bacteria,1R77Q@1224|Proteobacteria,1S1WT@1236|Gammaproteobacteria,1XMZT@135619|Oceanospirillales 135619|Oceanospirillales D Fibronectin type 3 domain - - - - - - - - - - - - - k59_173423_2 1151292.QEW_2472 3.53e-16 87.8 COG2887@1|root,COG2887@2|Bacteria,1TPIC@1239|Firmicutes,247TB@186801|Clostridia,25SE0@186804|Peptostreptococcaceae 186801|Clostridia L Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_173423_3 1392501.JIAC01000001_gene1519 2.74e-17 79.7 28J2E@1|root,2Z8YX@2|Bacteria,1TRF9@1239|Firmicutes,4H491@909932|Negativicutes 909932|Negativicutes S Protein of unknown function (DUF2815) - - - - - - - - - - - - DUF2815 k59_343302_2 444859.E3SIB0_9CAUD 4.78e-05 53.5 4QCZH@10239|Viruses,4QPND@28883|Caudovirales,4QI11@10662|Myoviridae 10662|Myoviridae S Bacteriophage T4 gp9/10-like protein - GO:0005575,GO:0019012,GO:0044423,GO:0098015,GO:0098025 - - - - - - - - - - - k59_343302_5 266779.Meso_0243 3.76e-36 133.0 COG3179@1|root,COG3179@2|Bacteria,1R71F@1224|Proteobacteria,2UD1N@28211|Alphaproteobacteria,43MAV@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S chitinase - - - - - - - - - - - - Glyco_hydro_19 k59_343302_9 76869.PputGB1_1746 6.22e-150 445.0 COG0507@1|root,COG0507@2|Bacteria,1R1AT@1224|Proteobacteria,1RS66@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Participates in initiation and elongation during chromosome replication - - - - - - - - - - - - - k59_136779_2 1506572.A0A097ZPG0_9CIRC 3.52e-36 138.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_14573_1 289376.THEYE_A0412 0.000259 47.4 COG0859@1|root,COG0859@2|Bacteria,3J1EW@40117|Nitrospirae 40117|Nitrospirae M Glycosyltransferase family 9 (heptosyltransferase) - - - - - - - - - - - - Glyco_transf_9 k59_270423_1 105154.Q9MBU6_9VIRU 1.37e-196 566.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_270423_2 1986029.Q9MBM7_9VIRU 4.6e-13 72.0 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_270423_7 1165094.RINTHH_3920 7.33e-75 239.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_234239_1 1463921.JODF01000008_gene5477 8.67e-06 57.4 COG5434@1|root,COG5434@2|Bacteria,2I4GP@201174|Actinobacteria 201174|Actinobacteria M Parallel beta-helix repeats - - - - - - - - - - - - Beta_helix,Pectate_lyase_3 k59_222376_1 1283079.M1ID95_9CAUD 2.66e-40 162.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_76133_1 1121940.AUDZ01000012_gene1108 4.06e-06 56.6 COG5295@1|root,COG5295@2|Bacteria,1N338@1224|Proteobacteria,1RPXV@1236|Gammaproteobacteria 1236|Gammaproteobacteria UW Autotransporter adhesin - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - ESPR,YadA_head,YadA_stalk k59_39439_2 546271.Selsp_1353 0.000399 46.2 COG5377@1|root,COG5377@2|Bacteria,1TS2Y@1239|Firmicutes,4H426@909932|Negativicutes 909932|Negativicutes L YqaJ viral recombinase family protein - - - - - - - - - - - - YqaJ k59_3562_1 82995.CR62_24080 1.37e-15 77.0 COG0582@1|root,COG0582@2|Bacteria,1MWBN@1224|Proteobacteria,1RPD0@1236|Gammaproteobacteria,4049X@613|Serratia 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k59_76137_1 247156.NFA_40330 1.97e-19 85.9 COG0863@1|root,COG0863@2|Bacteria,2I9DJ@201174|Actinobacteria,4G51U@85025|Nocardiaceae 201174|Actinobacteria L DNA methylase - - 2.1.1.113,2.1.1.72 ko:K00571,ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_343384_2 1609634.A0A0C5ANA6_9VIRU 9.49e-23 98.6 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_52642_1 1121947.AUHK01000002_gene944 7.05e-06 54.7 COG3941@1|root,COG5412@1|root,COG3941@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia,22HH1@1570339|Peptoniphilaceae 186801|Clostridia D Phage tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail k59_76907_1 1788447.A0A190WHJ9_9CIRC 6.98e-18 82.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_380684_1 1385658.U5KPZ6_9VIRU 4.34e-111 340.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_356406_2 1468411.X2L015_9CAUD 3.09e-07 56.6 4QB0T@10239|Viruses,4QV4X@35237|dsDNA viruses no RNA stage,4QPUT@28883|Caudovirales,4QKQK@10699|Siphoviridae 10699|Siphoviridae S Protein of unknown function (DUF669) - - - - - - - - - - - - - k59_344217_1 1609634.A0A0C5AFV4_9VIRU 6.29e-73 236.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_15302_2 41431.PCC8801_4554 3.32e-79 242.0 COG1192@1|root,COG1192@2|Bacteria,1G1EV@1117|Cyanobacteria,3KJGU@43988|Cyanothece 1117|Cyanobacteria D Cobyrinic acid ac-diamide synthase - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31,CbiA k59_211085_1 691965.D4P7D6_9CAUD 3.9e-63 224.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_307973_2 1327981.S0A2G1_9CAUD 9.61e-129 389.0 4QAYV@10239|Viruses,4QUZ7@35237|dsDNA viruses no RNA stage,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - k59_307973_3 246194.CHY_1680 4.51e-11 65.5 COG1783@1|root,COG1783@2|Bacteria,1TRQP@1239|Firmicutes,248E9@186801|Clostridia,42I1E@68295|Thermoanaerobacterales 186801|Clostridia S Terminase RNAseH like domain - - - ko:K06909 - - - - ko00000 - - - Terminase_2,Terminase_3,Terminase_3C k59_149823_1 1120973.AQXL01000096_gene3002 6.72e-37 142.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1TSMG@1239|Firmicutes,4HBFH@91061|Bacilli,279IG@186823|Alicyclobacillaceae 91061|Bacilli S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_15303_2 1155714.KB891988_gene1269 4.79e-15 77.0 COG0791@1|root,COG3409@1|root,COG0791@2|Bacteria,COG3409@2|Bacteria,2I61A@201174|Actinobacteria 201174|Actinobacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - NLPC_P60,PG_binding_1 k59_4306_1 1380347.JNII01000006_gene1446 6.15e-07 57.0 COG1749@1|root,COG2372@1|root,COG5184@1|root,COG1749@2|Bacteria,COG2372@2|Bacteria,COG5184@2|Bacteria,2I2X3@201174|Actinobacteria,4EUDH@85013|Frankiales 201174|Actinobacteria N Bacterial Ig-like domain - - - - - - - - - - - - Big_5,DUF4082,Mo-co_dimer,fn3 k59_65176_1 696281.Desru_1084 1.51e-18 92.4 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia 186801|Clostridia L snf2 family - - - - - - - - - - - - SNF2_N k59_295813_2 1379710.S5TNC2_9CIRC 1.86e-26 106.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_321041_2 348824.LPU83_1707 4.76e-07 57.4 28S81@1|root,2ZEJD@2|Bacteria,1RCNN@1224|Proteobacteria,2UUXX@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_4981_10 710243.XP_007596484.1 4.54e-05 56.2 2CNC5@1|root,2QV54@2759|Eukaryota,39S8X@33154|Opisthokonta,3NW2N@4751|Fungi,3QMXN@4890|Ascomycota,211EZ@147550|Sordariomycetes,1EVZF@1028384|Glomerellales 4751|Fungi O Glucan 1,3-beta-glucosidase - - 3.2.1.58 ko:K01210 ko00500,map00500 - R00308,R03115 RC00467 ko00000,ko00001,ko01000 - - - Pectate_lyase_3 k59_53342_1 2003327.CAPSD_BPCHP 7.17e-50 176.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_53396_1 1385658.U5KNR1_9VIRU 2.68e-77 242.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_271988_3 1692252.A0A0K1RL35_9CIRC 4.07e-27 108.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_175189_1 1609634.A0A0C5AFV4_9VIRU 3.53e-40 146.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_223900_1 1408311.JNJM01000048_gene89 4.19e-23 95.1 COG1611@1|root,COG1611@2|Bacteria,1V7HV@1239|Firmicutes,24JN5@186801|Clostridia,2PTJ9@265975|Oribacterium 186801|Clostridia S Belongs to the LOG family - - - - - - - - - - - - - k59_150648_2 886882.PPSC2_p0514 1.83e-50 174.0 2EN4Y@1|root,30UJG@2|Bacteria,1U1MI@1239|Firmicutes,4IB3Y@91061|Bacilli,273NQ@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - k59_345033_1 759914.BP951000_1469 2.86e-25 114.0 COG5283@1|root,COG5283@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - PhageMin_Tail k59_65838_2 1004149.AFOE01000041_gene1173 1.88e-05 53.9 COG0457@1|root,COG2911@1|root,COG0457@2|Bacteria,COG2911@2|Bacteria,4NPJI@976|Bacteroidetes,1I2IK@117743|Flavobacteriia 976|Bacteroidetes M Pkd domain containing protein - - - - - - - - - - - - - k59_175190_1 1071679.BG57_05880 1.06e-14 82.4 COG4974@1|root,COG4974@2|Bacteria,1QZ7D@1224|Proteobacteria,2WHIV@28216|Betaproteobacteria,1K6U5@119060|Burkholderiaceae 28216|Betaproteobacteria L Pfam:DUF3596 - - - ko:K14059 - - - - ko00000 - - - Arm-DNA-bind_2,Phage_integrase k59_199259_1 105154.Q9MBU6_9VIRU 3.11e-86 271.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_199259_2 1609634.A0A0C5ANA6_9VIRU 6.92e-10 64.7 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_235531_2 1028800.RG540_CH13810 5.69e-26 108.0 28MSK@1|root,2ZB0X@2|Bacteria,1R7CY@1224|Proteobacteria,2U2MY@28211|Alphaproteobacteria,4BJ92@82115|Rhizobiaceae 28211|Alphaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_271990_1 626887.J057_01705 5.29e-75 245.0 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,1RZ7H@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_138409_2 697282.Mettu_1302 1.06e-59 197.0 COG0535@1|root,COG0535@2|Bacteria,1PHAQ@1224|Proteobacteria 1224|Proteobacteria C Radical SAM - - - - - - - - - - - - Fer4_14,Radical_SAM,SPASM k59_90163_1 457415.HMPREF1006_02476 7.03e-23 100.0 COG3087@1|root,COG3087@2|Bacteria,3TAF9@508458|Synergistetes 508458|Synergistetes D Caudovirus prohead serine protease - - - - - - - - - - - - Peptidase_S78 k59_260425_1 1173025.GEI7407_1172 8.67e-85 265.0 COG1089@1|root,COG1089@2|Bacteria,1G0M4@1117|Cyanobacteria,1H6XT@1150|Oscillatoriales 1117|Cyanobacteria M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose gmd - 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd k59_273036_2 1609634.A0A0C5ANA6_9VIRU 4.7e-22 97.4 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_369805_1 33898.JRHJ01000001_gene713 1.19e-21 91.3 2EHNC@1|root,33BE4@2|Bacteria,2IPVK@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - Phage_tail_2 k59_151605_1 1209072.ALBT01000003_gene703 1.02e-73 238.0 COG0582@1|root,COG0582@2|Bacteria,1QWI5@1224|Proteobacteria,1T2VS@1236|Gammaproteobacteria 1236|Gammaproteobacteria L viral genome integration into host DNA - - - - - - - - - - - - - k59_16819_2 61647.LG71_19615 6.22e-22 90.9 COG4570@1|root,COG4570@2|Bacteria,1N92D@1224|Proteobacteria,1S5SJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC rusA - 3.1.22.4 ko:K01160 - - - - ko00000,ko01000,ko03400 - - - RusA k59_103073_2 1536592.A0A088FB29_9VIRU 3.41e-76 238.0 4QB5I@10239|Viruses 10239|Viruses S N-methyltransferase activity - - - - - - - - - - - - - k59_139371_1 36080.S2KHZ6 6.6e-08 58.9 COG1061@1|root,2QT4U@2759|Eukaryota,38GE0@33154|Opisthokonta,3NWXY@4751|Fungi,1GSGB@112252|Fungi incertae sedis 4751|Fungi A Type III restriction enzyme, res subunit irc3 GO:0000002,GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005739,GO:0005759,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0007005,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010467,GO:0010501,GO:0016043,GO:0016070,GO:0016072,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022613,GO:0031974,GO:0031981,GO:0032042,GO:0033676,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042623,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070035,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 - ko:K17677 - - - - ko00000,ko01000,ko03029 - - - Helicase_C,ResIII k59_103079_2 1692250.A0A0K1RLR1_9CIRC 1.27e-29 113.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_322002_1 1370120.AUWR01000011_gene999 1.6e-07 59.7 COG0537@1|root,COG1061@1|root,COG1974@1|root,COG2932@1|root,COG3886@1|root,COG0537@2|Bacteria,COG1061@2|Bacteria,COG1974@2|Bacteria,COG2932@2|Bacteria,COG3886@2|Bacteria,2GJ4Y@201174|Actinobacteria,23706@1762|Mycobacteriaceae 201174|Actinobacteria L helicase superfamily c-terminal domain - - - - - - - - - - - - DUF3427,Helicase_C,PLDc_2,ResIII k59_54288_2 691966.D4P730_9CAUD 4.29e-48 185.0 4QG4M@10239|Viruses,4R0DJ@35237|dsDNA viruses no RNA stage,4QR3G@28883|Caudovirales,4QM6E@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_213026_1 9483.ENSCJAP00000022729 7.47e-12 70.9 COG0553@1|root,KOG1000@2759|Eukaryota,38C05@33154|Opisthokonta,3BE0M@33208|Metazoa,3CT9F@33213|Bilateria,4833X@7711|Chordata,4986G@7742|Vertebrata,3J96H@40674|Mammalia,35INY@314146|Euarchontoglires,4MI77@9443|Primates 33208|Metazoa B regulator of chromatin, subfamily a-like SMARCAL1 GO:0000278,GO:0000723,GO:0000724,GO:0000725,GO:0000726,GO:0000733,GO:0001325,GO:0001501,GO:0001525,GO:0001568,GO:0001944,GO:0002376,GO:0002520,GO:0003674,GO:0003676,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005700,GO:0005705,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006302,GO:0006310,GO:0006355,GO:0006357,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007049,GO:0007275,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009378,GO:0009653,GO:0009790,GO:0009888,GO:0009889,GO:0009987,GO:0010171,GO:0010172,GO:0010468,GO:0010556,GO:0010709,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030097,GO:0030491,GO:0031297,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0032200,GO:0032392,GO:0032501,GO:0032502,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0035239,GO:0035295,GO:0035861,GO:0036292,GO:0036310,GO:0040007,GO:0042592,GO:0042623,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044464,GO:0045002,GO:0045003,GO:0045005,GO:0046483,GO:0048513,GO:0048514,GO:0048534,GO:0048589,GO:0048598,GO:0048646,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051216,GO:0051252,GO:0051276,GO:0051716,GO:0060249,GO:0060255,GO:0061306,GO:0061448,GO:0065007,GO:0065008,GO:0070013,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0072358,GO:0072359,GO:0080090,GO:0090304,GO:0090656,GO:0090734,GO:0090737,GO:0097159,GO:0097617,GO:0098687,GO:0140097,GO:1901360,GO:1901363,GO:1901576,GO:1903506,GO:1990163,GO:2000112,GO:2001141 3.6.4.12 ko:K14440 - - - - ko00000,ko01000,ko03036 - - - HARP,Helicase_C,SNF2_N k59_139374_1 1178825.ALIH01000009_gene1304 2.63e-21 95.5 COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,1HXB2@117743|Flavobacteriia 976|Bacteroidetes M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose rmlD - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind k59_224951_1 1609634.A0A0C5ANA6_9VIRU 1.56e-09 62.4 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_31194_1 675817.VDA_000908 5.59e-13 74.3 COG0454@1|root,COG0503@1|root,COG1040@1|root,COG0456@2|Bacteria,COG0503@2|Bacteria,COG1040@2|Bacteria,1QV41@1224|Proteobacteria,1RSAP@1236|Gammaproteobacteria,1XVT9@135623|Vibrionales 135623|Vibrionales K acetyltransferase - - - - - - - - - - - - - k59_370753_2 760142.Hipma_1002 1.13e-13 76.6 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,42M8S@68525|delta/epsilon subdivisions,2WNG8@28221|Deltaproteobacteria,2M6PR@213113|Desulfurellales 28221|Deltaproteobacteria K ParB-like nuclease domain parB - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_55199_1 412597.AEPN01000059_gene3564 9.84e-43 158.0 COG3505@1|root,COG3505@2|Bacteria 412597.AEPN01000059_gene3564|- U unidirectional conjugation - - - - - - - - - - - - - k59_6787_1 1234888.K0A2J2_9VIRU 3.39e-43 156.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_200985_1 469660.A8HNV7_9CAUD 1.05e-05 53.1 4QBDF@10239|Viruses,4QTX8@28883|Caudovirales,4QP0C@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_115590_1 1385658.U5KPZ6_9VIRU 6.33e-77 249.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_79603_1 395493.BegalDRAFT_1453 7.4e-12 68.6 COG0582@1|root,COG0582@2|Bacteria,1MWBN@1224|Proteobacteria,1RPD0@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k59_92444_1 1382306.JNIM01000001_gene4138 1.05e-07 60.1 COG0358@1|root,COG0358@2|Bacteria,2G65X@200795|Chloroflexi 200795|Chloroflexi L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k59_43092_3 76636.JOEC01000001_gene1138 4.94e-46 170.0 2AYQQ@1|root,31QVM@2|Bacteria,2HT0W@201174|Actinobacteria,4FR6P@85023|Microbacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_67774_2 1122609.AUGT01000008_gene2868 6.86e-22 108.0 COG0366@1|root,COG0515@1|root,COG2133@1|root,COG3227@1|root,COG4733@1|root,COG0366@2|Bacteria,COG0515@2|Bacteria,COG2133@2|Bacteria,COG3227@2|Bacteria,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - 3.2.1.3 ko:K01178,ko:K14645,ko:K18546 ko00500,ko01100,ko02024,map00500,map01100,map02024 - R01790,R01791,R06199 - ko00000,ko00001,ko01000,ko01002,ko03110 - GH15 - Alpha-amylase,GSDH,He_PIG,PKD,Pro_Al_protease,SLH,Trypsin,fn3 k59_186665_2 658086.HMPREF0994_05076 0.000126 46.2 COG3103@1|root,COG3103@2|Bacteria,1W0I8@1239|Firmicutes,253VT@186801|Clostridia 186801|Clostridia T Sh3 type 3 domain protein - - - - - - - - - - - - - k59_249753_1 691965.D4P7D3_9CAUD 1.79e-07 54.7 4QAYV@10239|Viruses,4QUZ7@35237|dsDNA viruses no RNA stage,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - k59_249753_2 691965.D4P7D6_9CAUD 1.5e-129 401.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_55332_3 1618257.A0A0C5IBI9_9CIRC 1.02e-09 66.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_274082_2 290633.GOX2477 6.08e-07 55.1 2CHRY@1|root,30Z9E@2|Bacteria,1RGQK@1224|Proteobacteria,2U9J0@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - RecT k59_299821_11 694427.Palpr_1970 2.55e-14 77.0 COG4675@1|root,COG4675@2|Bacteria 2|Bacteria M tail collar domain protein - - - - - - - - - - - - Collar k59_371787_1 1217705.F900_01055 7.63e-11 63.2 2DYV8@1|root,32V63@2|Bacteria,1QNWV@1224|Proteobacteria,1ST2X@1236|Gammaproteobacteria,3NNP1@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_289100_1 935948.KE386495_gene1350 7.21e-06 49.3 2BX5K@1|root,32R8G@2|Bacteria,1V9DD@1239|Firmicutes 1239|Firmicutes L HNH endonuclease - - - - - - - - - - - - HNH_3 k59_56353_2 1379719.S5TMX6_9CIRC 2.11e-37 143.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_80800_3 1429916.X566_17650 2.42e-11 64.7 COG5055@1|root,COG5055@2|Bacteria,1QWK7@1224|Proteobacteria,2U07V@28211|Alphaproteobacteria,3JU49@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Protein of unknown function (DUF968) - - - - - - - - - - - - DUF968,ERF k59_300049_1 1280950.HJO_16280 3.83e-24 106.0 COG0500@1|root,COG1216@1|root,COG1216@2|Bacteria,COG2226@2|Bacteria,1RBVM@1224|Proteobacteria,2U91B@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Glycosyl transferase family 2 - - - - - - - - - - - - CmcI,Glycos_transf_2 k59_250730_1 86416.Clopa_3150 9.29e-06 47.8 COG1032@1|root,COG1032@2|Bacteria,1TRY3@1239|Firmicutes,249Q1@186801|Clostridia,36HCS@31979|Clostridiaceae 186801|Clostridia C Psort location Cytoplasmic, score - - - - - - - - - - - - - k59_348209_1 2754.EH55_13250 2.67e-10 65.5 COG0419@1|root,COG3064@1|root,COG3941@1|root,COG0419@2|Bacteria,COG3064@2|Bacteria,COG3941@2|Bacteria 2|Bacteria O tape measure - - 2.1.1.80,3.1.1.61 ko:K03529,ko:K13582,ko:K13924 ko02020,ko02030,ko04112,map02020,map02030,map04112 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035,ko03036 - - - AAA_15,AAA_21 k59_44138_1 1121943.KB899989_gene3404 5.78e-24 107.0 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,1RNAN@1236|Gammaproteobacteria,1XH5K@135619|Oceanospirillales 135619|Oceanospirillales L helicase superfamily c-terminal domain - - - ko:K19789 - - - - ko00000,ko03400 - - - Helicase_C,ResIII k59_32447_1 1131814.JAFO01000001_gene2083 6.09e-46 166.0 COG0507@1|root,COG5362@1|root,COG0507@2|Bacteria,COG5362@2|Bacteria,1R90H@1224|Proteobacteria,2U236@28211|Alphaproteobacteria 28211|Alphaproteobacteria L TIGRFAM Phage - - - - - - - - - - - - Terminase_6 k59_104946_1 942016.E9NIH0_9CAUD 2.02e-53 188.0 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_93593_1 644107.SL1157_2511 2.61e-07 60.5 COG3391@1|root,COG3391@2|Bacteria,1MXN7@1224|Proteobacteria,2TR83@28211|Alphaproteobacteria,4NAE9@97050|Ruegeria 28211|Alphaproteobacteria S GTA TIM-barrel-like domain - - - - - - - - - - - - GTA_TIM,Phage-tail_3 k59_93593_3 631454.N177_3939 3.52e-23 104.0 COG5449@1|root,COG5449@2|Bacteria,1MXK2@1224|Proteobacteria,2TTWS@28211|Alphaproteobacteria,1JNAE@119043|Rhodobiaceae 28211|Alphaproteobacteria S Phage conserved hypothetical protein BR0599 - - - - - - - - - - - - DUF2163,Phage_BR0599 k59_93593_4 323098.Nwi_0796 8.87e-29 113.0 COG5448@1|root,COG5448@2|Bacteria,1MXM8@1224|Proteobacteria,2U8KA@28211|Alphaproteobacteria,3K44P@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Conserved hypothetical protein 2217 (DUF2460) - - - - - - - - - - - - DUF2460 k59_93593_5 504346.TMP_BPPAJ 1.73e-11 65.9 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - GO:0008150,GO:0044403,GO:0044409,GO:0044411,GO:0044419,GO:0051701,GO:0051704,GO:0051828,GO:0051830,GO:0085027 - - - - - - - - - - - k59_289117_1 1498011.A0A096XUT2_9CAUD 2.04e-20 88.6 4QAK6@10239|Viruses,4QRSI@28883|Caudovirales,4QNEJ@10744|Podoviridae 10744|Podoviridae S Pfam:DUF5309 - - - - - - - - - - - - - k59_56373_1 1609634.A0A0C5AFV4_9VIRU 5.28e-41 152.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_117801_3 1192124.LIG30_0373 3.75e-33 119.0 COG4678@1|root,COG4678@2|Bacteria,1R92U@1224|Proteobacteria,2VUZ6@28216|Betaproteobacteria,1K9F9@119060|Burkholderiaceae 28216|Betaproteobacteria G lysozyme - - - - - - - - - - - - Phage_lysozyme k59_94809_1 1234888.K0A2J2_9VIRU 6.14e-68 223.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_188207_3 1379722.S5SY31_9CIRC 1.64e-95 288.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_216374_2 1385658.U5KQQ9_9VIRU 1.13e-13 74.7 4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_349378_2 1437448.AZRT01000050_gene164 6.5e-44 160.0 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,2TUXC@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Type III restriction enzyme res subunit - - - ko:K19789 - - - - ko00000,ko03400 - - - DUF3427,HIT,Helicase_C,PLDc_2,ResIII,UPF0547 k59_360636_1 753084.F4YCR0_9CAUD 4.06e-34 133.0 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QPEB@28883|Caudovirales,4QKNC@10699|Siphoviridae 10699|Siphoviridae S hydrolase activity - - - - - - - - - - - - - k59_301231_3 1040987.AZUY01000006_gene1806 1.47e-25 117.0 COG3598@1|root,COG3598@2|Bacteria,1R4GJ@1224|Proteobacteria,2TUNT@28211|Alphaproteobacteria 28211|Alphaproteobacteria L AAA domain - - - - - - - - - - - - AAA_25 k59_69910_4 1120953.AUBH01000001_gene618 0.000761 43.9 COG1228@1|root,COG1228@2|Bacteria,1MXXR@1224|Proteobacteria,1RRK7@1236|Gammaproteobacteria,46458@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1,Amidohydro_3 k59_337520_2 768710.DesyoDRAFT_5152 1.91e-05 51.6 2DT4K@1|root,33INK@2|Bacteria,1VQEE@1239|Firmicutes,253M4@186801|Clostridia 1239|Firmicutes - - - - - - - - - - - - - - - k59_312782_1 1692245.A0A0K1RL45_9CIRC 6.1e-13 71.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_251857_3 1370122.JHXQ01000018_gene66 9.07e-35 140.0 COG5283@1|root,COG5283@2|Bacteria,1NFKU@1224|Proteobacteria,2U1H4@28211|Alphaproteobacteria,4BCD7@82115|Rhizobiaceae 28211|Alphaproteobacteria S Phage-related minor tail protein - - - - - - - - - - - - Peptidase_M15_3,PhageMin_Tail k59_301282_1 86106.I862_04325 1.1e-45 171.0 COG5511@1|root,COG5511@2|Bacteria,1MVN4@1224|Proteobacteria,2TSGI@28211|Alphaproteobacteria,47G98@766|Rickettsiales 766|Rickettsiales S Phage portal protein, lambda family - - - - - - - - - - - - Phage_portal_2 k59_276197_1 1176422.I6R1A9_9CAUD 4.94e-65 229.0 4QFI3@10239|Viruses,4QZBZ@35237|dsDNA viruses no RNA stage,4QUAE@28883|Caudovirales,4QN5M@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_263662_3 1219035.NT2_13_00580 8.15e-76 249.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_83028_1 1420600.W5RNT1_9CIRC 1.24e-19 90.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_302374_1 1005994.GTGU_01420 6.16e-43 163.0 28HCK@1|root,2Z7PE@2|Bacteria,1NK7S@1224|Proteobacteria,1S03Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_34697_1 1096930.L284_17050 3.03e-68 226.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT52@1224|Proteobacteria,2TVNI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_2 k59_96216_1 1144313.PMI10_00661 1.21e-10 69.7 2DNIX@1|root,32XR6@2|Bacteria,4NU21@976|Bacteroidetes,1I3XV@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_264712_1 1234888.K0A2J2_9VIRU 1.02e-64 213.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_350441_1 1458357.BG58_33085 1.3e-14 82.8 COG5283@1|root,COG5283@2|Bacteria,1R5FU@1224|Proteobacteria,2VPNW@28216|Betaproteobacteria,1K6D9@119060|Burkholderiaceae 28216|Betaproteobacteria D tape measure - - - - - - - - - - - - - k59_386120_1 2003327.CAPSD_BPCHP 1.2e-39 151.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_20975_2 691965.D4P7D3_9CAUD 3.86e-179 514.0 4QAYV@10239|Viruses,4QUZ7@35237|dsDNA viruses no RNA stage,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - k59_326667_1 1556290.A0A0A0RM00_9CAUD 1.33e-65 219.0 4QAXQ@10239|Viruses,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_264715_2 1692256.A0A0K1RL85_9CIRC 5.5e-127 372.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_386129_1 1609634.A0A0C5AFT2_9VIRU 2.47e-89 273.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_189091_1 1283077.M1HLI2_9CAUD 1.25e-11 77.0 4QC24@10239|Viruses,4QZPR@35237|dsDNA viruses no RNA stage,4QRZK@28883|Caudovirales,4QP0N@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_9829_1 1493509.A0A0E3HQ43_9CAUD 1.97e-23 100.0 4QHDM@10239|Viruses,4QRD0@28883|Caudovirales,4QI2W@10662|Myoviridae 10662|Myoviridae S Terminase-like family - GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016032,GO:0016043,GO:0016787,GO:0016788,GO:0019058,GO:0019068,GO:0019069,GO:0019072,GO:0019075,GO:0022607,GO:0032991,GO:0034641,GO:0043170,GO:0043493,GO:0044085,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0046483,GO:0046797,GO:0051704,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0098009,GO:1901360,GO:1902494,GO:1904949 - - - - - - - - - - - k59_34850_5 349102.Rsph17025_0104 2.75e-25 118.0 COG0616@1|root,COG0616@2|Bacteria,1QGPW@1224|Proteobacteria,2TUGQ@28211|Alphaproteobacteria,1FBCT@1060|Rhodobacter 28211|Alphaproteobacteria OU PFAM peptidase - - - - - - - - - - - - Peptidase_S49 k59_364335_1 1122931.AUAE01000001_gene741 2.51e-09 65.9 COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,2FMV1@200643|Bacteroidia,22WQI@171551|Porphyromonadaceae 976|Bacteroidetes L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k59_364335_2 936572.HMPREF1148_0674 6.09e-14 70.5 2E3FM@1|root,32YEF@2|Bacteria,1VF4E@1239|Firmicutes 1239|Firmicutes S VRR-NUC domain - - - - - - - - - - - - VRR_NUC k59_23982_1 1609634.A0A0C5AFV4_9VIRU 2.54e-42 155.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_388356_3 1385658.U5KPZ6_9VIRU 2.76e-100 319.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_267271_1 655097.C8ZKE0_9CAUD 1.36e-22 105.0 4QBG4@10239|Viruses,4QUZA@35237|dsDNA viruses no RNA stage,4QRSK@28883|Caudovirales,4QP0Z@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_24015_1 691965.D4P7I3_9CAUD 4.02e-62 214.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_388358_6 1609634.A0A0C5AFT2_9VIRU 2.97e-120 356.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_388358_9 1609634.A0A0C5AFV4_9VIRU 6.78e-231 654.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_388358_10 1609634.A0A0C5ANA6_9VIRU 1.03e-11 70.1 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_388361_1 1618247.A0A0C5IMK7_9CIRC 1.04e-08 61.6 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_364340_2 478749.BRYFOR_08514 1.3e-35 125.0 2ARVA@1|root,31H70@2|Bacteria,1V7JT@1239|Firmicutes,24JPE@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - HK97-gp10_like k59_364340_3 742733.HMPREF9469_05020 2.27e-229 734.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,221IX@1506553|Lachnoclostridium 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_364340_5 411460.RUMTOR_01333 1.23e-90 283.0 28K55@1|root,2Z9TX@2|Bacteria,1V0P7@1239|Firmicutes,24DCX@186801|Clostridia,3Y0KI@572511|Blautia 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - Sipho_Gp37 k59_364340_8 742740.HMPREF9474_02251 4.07e-18 78.2 2EK5K@1|root,33DW0@2|Bacteria,1UU54@1239|Firmicutes,255II@186801|Clostridia 186801|Clostridia S Putative phage holin Dp-1 - - - - - - - - - - - - Phage_holin_Dp1 k59_24043_1 758.BBIX01000009_gene1627 4.76e-35 129.0 2B9XI@1|root,323AV@2|Bacteria,1NZM3@1224|Proteobacteria,1SQ2M@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Protein of unknown function (DUF1071) - - - - - - - - - - - - DUF1071 k59_267301_2 1121459.AQXE01000001_gene2767 8.85e-21 90.9 COG3023@1|root,COG3023@2|Bacteria,1N032@1224|Proteobacteria,432MJ@68525|delta/epsilon subdivisions,2WX9X@28221|Deltaproteobacteria,2MCUI@213115|Desulfovibrionales 28221|Deltaproteobacteria V PFAM N-acetylmuramoyl-L-alanine amidase family 2 - - - - - - - - - - - - Amidase_2 k59_364357_1 1609634.A0A0C5AFV4_9VIRU 2.13e-51 181.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_388504_1 1618248.A0A0C5IB82_9CIRC 3.76e-55 185.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388504_3 1618248.A0A0C5IB82_9CIRC 1.57e-27 108.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_157997_1 1038860.AXAP01000015_gene2060 9.98e-44 154.0 COG0741@1|root,COG0741@2|Bacteria,1MX5R@1224|Proteobacteria,2TVHC@28211|Alphaproteobacteria,3JUU6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Transglycosylase SLT domain - - - - - - - - - - - - SLT k59_72923_5 768710.DesyoDRAFT_5152 6.01e-06 53.1 2DT4K@1|root,33INK@2|Bacteria,1VQEE@1239|Firmicutes,253M4@186801|Clostridia 1239|Firmicutes - - - - - - - - - - - - - - - k59_352408_3 1420600.W5RNT1_9CIRC 7.09e-34 132.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_279527_7 1234888.K0A2J2_9VIRU 2.03e-107 330.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_230903_2 1618248.A0A0C5IB82_9CIRC 4.72e-90 277.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_206610_1 1123277.KB893184_gene4032 6.67e-18 92.4 COG0467@1|root,COG0467@2|Bacteria,4NIAQ@976|Bacteroidetes 976|Bacteroidetes T Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - AAA_25 k59_206610_2 411473.RUMCAL_00274 8.65e-108 333.0 COG0553@1|root,COG0553@2|Bacteria,1TP2C@1239|Firmicutes,24DVA@186801|Clostridia,3WP9W@541000|Ruminococcaceae 186801|Clostridia KL DEAD-like helicases superfamily - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_328111_4 1234888.K0A2J2_9VIRU 4.04e-130 393.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_170163_2 1609634.A0A0C5ANA6_9VIRU 7.31e-19 89.7 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_170163_7 1609634.A0A0C5AFT2_9VIRU 1.37e-120 357.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_170163_10 186617.M9M8L2_9VIRU 2.22e-152 444.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_218784_2 1136163.M565_ctg5P0621 5.32e-55 174.0 2DN9C@1|root,32W8M@2|Bacteria,1N2J0@1224|Proteobacteria,1SBVC@1236|Gammaproteobacteria,1XY4C@135623|Vibrionales 135623|Vibrionales S Phage related protein - - - - - - - - - - - - DUF3693 k59_121539_1 145579.CAPSD_BPPHM 2.02e-67 223.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_170169_1 1692255.A0A0K1RL52_9CIRC 2.23e-62 203.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_85125_1 392499.Swit_4440 4.91e-64 206.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,2U1P9@28211|Alphaproteobacteria,2KAJR@204457|Sphingomonadales 204457|Sphingomonadales S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6C k59_60843_5 1476391.X5KNB4_9CAUD 1.46e-37 152.0 4QAXA@10239|Viruses,4QYJI@35237|dsDNA viruses no RNA stage,4QQ1A@28883|Caudovirales,4QNU7@10744|Podoviridae 10744|Podoviridae S metallopeptidase activity - - - - - - - - - - - - - k59_291682_5 1385658.U5KPZ6_9VIRU 3.03e-179 520.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_61659_2 1226994.AMZB01000137_gene5401 6.61e-52 180.0 28PTM@1|root,2ZCEU@2|Bacteria,1R5DD@1224|Proteobacteria 1224|Proteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_85738_4 1231190.NA8A_00010 9.94e-19 89.0 COG2755@1|root,COG2755@2|Bacteria 2|Bacteria E lipolytic protein G-D-S-L family - - - - - - - - - - - - Cadherin,Calx-beta,FG-GAP,Flg_new,Laminin_G_3,Lipase_GDSL_2,M60-like_N,PA14,Peptidase_M60 k59_365100_2 926562.Oweho_1765 0.000622 44.7 COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,1HZ6M@117743|Flavobacteriia,2PA4P@246874|Cryomorphaceae 976|Bacteroidetes C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) pdhC - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k59_304523_1 186617.M9MJB7_9VIRU 3.04e-06 55.1 4QB1C@10239|Viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_268014_3 716928.AJQT01000109_gene1217 3.12e-06 48.1 2FEUE@1|root,346TC@2|Bacteria,1MZPB@1224|Proteobacteria,2UC4Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_158783_1 1217713.F993_01646 1.5e-22 95.5 COG3179@1|root,COG3179@2|Bacteria,1R71F@1224|Proteobacteria,1RZTY@1236|Gammaproteobacteria,3NJ60@468|Moraxellaceae 1236|Gammaproteobacteria S Chitinase class I - - - - - - - - - - - - Glyco_hydro_19,PG_binding_1 k59_158783_4 1304877.KI519399_gene4996 1.87e-144 508.0 COG0454@1|root,COG0827@1|root,COG1203@1|root,COG0456@2|Bacteria,COG0827@2|Bacteria,COG1203@2|Bacteria,1QZ6D@1224|Proteobacteria,2U5JW@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA restriction-modification system - - - - - - - - - - - - AAA_34 k59_85834_1 89187.ISM_05190 9.41e-23 99.4 COG5281@1|root,COG5281@2|Bacteria,1R47M@1224|Proteobacteria,2TUIV@28211|Alphaproteobacteria,46QA2@74030|Roseovarius 28211|Alphaproteobacteria S COG5281 Phage-related minor tail protein - - - - - - - - - - - - - k59_134370_1 105154.Q9MBU6_9VIRU 2.79e-86 278.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_49481_2 1788454.A0A190WHE4_9CIRC 4.85e-14 74.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_146709_2 477184.KYC_18280 4.38e-27 108.0 COG3740@1|root,COG3740@2|Bacteria,1NHKT@1224|Proteobacteria,2VV07@28216|Betaproteobacteria 28216|Betaproteobacteria S Phage prohead protease, HK97 family - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78 k59_61751_1 35241.Q9XJE8_BPTU2 7.4e-08 55.1 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_25085_1 1117943.SFHH103_00150 7.79e-14 76.6 2DPZ1@1|root,3340X@2|Bacteria,1R2EE@1224|Proteobacteria,2TZIB@28211|Alphaproteobacteria,4BP2Q@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_98023_1 935848.JAEN01000011_gene1848 3.46e-55 182.0 COG3409@1|root,COG3409@2|Bacteria,1RAYU@1224|Proteobacteria,2U6D1@28211|Alphaproteobacteria,2PXU7@265|Paracoccus 28211|Alphaproteobacteria M N-acetylmuramidase - - - - - - - - - - - - Muraidase,PG_binding_1 k59_243719_1 938709.AUSH02000051_gene230 0.000791 52.0 COG4733@1|root,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - - - - - - - - - - - - k59_208550_1 2003327.CAPSD_BPCHP 2.04e-13 76.6 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_293578_2 1385658.U5KPZ6_9VIRU 6.06e-193 556.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_293578_4 1165094.RINTHH_3920 4.31e-69 224.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_135345_1 1234888.K0A2J2_9VIRU 3.45e-48 171.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_318005_1 742733.HMPREF9469_05030 3.42e-36 137.0 28JK5@1|root,2Z9D1@2|Bacteria,1UJZJ@1239|Firmicutes,24D64@186801|Clostridia,222M5@1506553|Lachnoclostridium 186801|Clostridia S Caudovirus prohead serine protease - - - - - - - - - - - - Peptidase_S78 k59_305760_1 1234888.K0A2J2_9VIRU 7.41e-64 213.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_38174_1 1370121.AUWS01000008_gene5580 3.3e-29 129.0 COG0791@1|root,COG5632@1|root,COG0791@2|Bacteria,COG5632@2|Bacteria,2IH42@201174|Actinobacteria 201174|Actinobacteria M N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2,LGFP k59_38174_2 1210884.HG799463_gene10190 2.86e-07 58.2 COG3209@1|root,COG3209@2|Bacteria,2IY61@203682|Planctomycetes 203682|Planctomycetes M TIGRFAM RHS repeat-associated core domain - - - - - - - - - - - - FG-GAP,RHS_repeat k59_38176_1 926551.KB900709_gene1100 9.29e-06 52.8 COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,1HWYY@117743|Flavobacteriia,1EQI9@1016|Capnocytophaga 976|Bacteroidetes M N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA bshA - - ko:K00754 - - - - ko00000,ko01000 - GT4 - Glyco_transf_4,Glycos_transf_1 k59_281905_3 1137269.AZWL01000002_gene6168 4.67e-12 65.9 COG1652@1|root,COG1652@2|Bacteria,2GK68@201174|Actinobacteria 201174|Actinobacteria M domain protein - - - ko:K21687 - - - - ko00000 - GH23 - LysM,Transglycosylas k59_26014_2 1475143.W8SNN0_9CIRC 1.7e-23 105.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_160833_1 1537917.JU82_03700 1.52e-13 71.2 COG0553@1|root,COG0553@2|Bacteria 2|Bacteria L helicase activity - - - - - - - - - - - - Helicase_C,PLDc_2,ResIII,SNF2_N k59_124591_1 1609634.A0A0C5AFV4_9VIRU 1.67e-62 210.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_63795_5 1208918.CDEE_0591 1.37e-06 56.2 COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2VHDG@28216|Betaproteobacteria,1KPN9@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria I Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep k59_2876_1 592028.GCWU000321_01359 2.55e-55 189.0 COG0553@1|root,COG0553@2|Bacteria,1TP2C@1239|Firmicutes,4H2V4@909932|Negativicutes 909932|Negativicutes KL DEAD-like helicases superfamily - - - - - - - - - - - - N6_N4_Mtase k59_99897_1 1234888.K0A2J2_9VIRU 1.47e-72 234.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_294363_1 716928.AJQT01000109_gene1226 2.34e-47 157.0 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2U7RQ@28211|Alphaproteobacteria,4BAG3@82115|Rhizobiaceae 28211|Alphaproteobacteria G Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_257858_1 658086.HMPREF0994_01340 1.49e-32 126.0 COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,27IB7@186928|unclassified Lachnospiraceae 186801|Clostridia M DegT/DnrJ/EryC1/StrS aminotransferase family - - - - - - - - - - - - DegT_DnrJ_EryC1 k59_257858_2 626522.GCWU000325_00073 2.59e-20 87.0 COG0662@1|root,COG0662@2|Bacteria,4NQ4K@976|Bacteroidetes,2FSU2@200643|Bacteroidia,1WDJT@1283313|Alloprevotella 976|Bacteroidetes G WxcM-like, C-terminal wxcM - - - - - - - - - - - FdtA k59_258002_2 1217705.F900_01036 2.04e-14 76.6 COG5527@1|root,COG5527@2|Bacteria,1R2VT@1224|Proteobacteria,1T5YN@1236|Gammaproteobacteria,3NTUV@468|Moraxellaceae 1236|Gammaproteobacteria L Helix-turn-helix domain - - - - - - - - - - - - HTH_36 k59_355306_1 1121459.AQXE01000001_gene2748 2.1e-33 122.0 2AGTB@1|root,3171D@2|Bacteria,1RJGM@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - DUF2833 k59_294510_1 105154.Q9MBU6_9VIRU 3.91e-113 342.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_306806_1 471855.Shel_27870 2.39e-26 111.0 COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria,4CUUP@84998|Coriobacteriia 84998|Coriobacteriia L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_148509_3 573174.M4MBC3_9VIRU 1.01e-45 161.0 4QBY0@10239|Viruses,4QW35@35237|dsDNA viruses no RNA stage 10239|Viruses S AAA domain - - - - - - - - - - - - - k59_270029_1 1498011.A0A096XUS7_9CAUD 2.47e-44 177.0 4QAUF@10239|Viruses,4QQIV@28883|Caudovirales,4QNZ6@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_380317_1 1304874.JAFY01000002_gene708 1.79e-09 63.5 COG0209@1|root,COG0209@2|Bacteria,3TAE6@508458|Synergistetes 508458|Synergistetes F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen - - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN k59_258715_2 428125.CLOLEP_03914 8.23e-06 54.3 COG1215@1|root,COG1216@1|root,COG2227@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,COG2227@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia,3WHZS@541000|Ruminococcaceae 186801|Clostridia M Glycosyltransferase, group 2 family protein - - - ko:K20444 - - - - ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 - Glycos_transf_2 k59_210705_3 504832.OCAR_4842 3.63e-13 70.5 COG0791@1|root,COG0791@2|Bacteria,1RK6X@1224|Proteobacteria,2U93K@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Phage cell wall peptidase, NlpC P60 family - - - - - - - - - - - - NLPC_P60 k59_64757_2 1609634.A0A0C5ANA6_9VIRU 4.41e-18 85.9 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_64757_4 1609634.A0A0C5AFV4_9VIRU 2.36e-150 444.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_173824_2 406818.XBJ1_0385 1.43e-44 162.0 COG5424@1|root,COG5424@2|Bacteria,1PIA6@1224|Proteobacteria,1SJXQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Iron-containing redox enzyme - - - - - - - - - - - - Haem_oxygenas_2 k59_137140_2 1692257.A0A0K1RL39_9CIRC 2.35e-13 75.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_246505_1 105154.Q9MBT9_9VIRU 3.54e-12 63.2 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_307760_3 10228.TriadP52877 2.24e-05 51.6 2D04N@1|root,2SCSW@2759|Eukaryota,3AE35@33154|Opisthokonta 33154|Opisthokonta - - - - - - - - - - - - - - - k59_52460_1 717772.THIAE_06260 8.67e-33 130.0 COG4123@1|root,COG4123@2|Bacteria,1R93X@1224|Proteobacteria,1S0JD@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4942) - - - - - - - - - - - - DUF4942 k59_295525_1 411468.CLOSCI_00575 6.42e-42 155.0 COG0270@1|root,COG0270@2|Bacteria,1V3W2@1239|Firmicutes,24HK1@186801|Clostridia,22348@1506553|Lachnoclostridium 186801|Clostridia L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K17398 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko03032,ko03036 - - - DNA_methylase k59_88974_1 756277.M1PJJ8_9VIRU 1.48e-23 107.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage 10239|Viruses S DnaB-like helicase C terminal domain - - - - - - - - - - - - - k59_174003_2 278957.ABEA03000173_gene2450 3.7e-10 63.2 2BS3N@1|root,32M4F@2|Bacteria,46YQK@74201|Verrucomicrobia,3KA06@414999|Opitutae 414999|Opitutae - - - - - - - - - - - - - - - k59_284467_2 1112204.GPOL_c32270 1.25e-06 54.3 2CESS@1|root,33C6B@2|Bacteria,2GYQ3@201174|Actinobacteria,4GG6M@85026|Gordoniaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_15102_2 1618259.A0A0C5I2B5_9CIRC 2.53e-09 61.6 4QE84@10239|Viruses,4QUKR@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_368022_1 28176.CF66_1032 9.52e-18 87.4 COG0749@1|root,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1XUAZ@135623|Vibrionales 135623|Vibrionales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_198211_1 865861.AZSU01000001_gene227 7.99e-74 252.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,36DHP@31979|Clostridiaceae 186801|Clostridia L DNA polymerase dnaE - 2.7.7.7 ko:K02337,ko:K14162 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k59_343960_2 1379719.S5TMX6_9CIRC 3.58e-07 57.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_222932_2 556269.ACDQ01000006_gene1592 1.04e-43 169.0 2CENN@1|root,32VYV@2|Bacteria,1N4RC@1224|Proteobacteria,2W1J6@28216|Betaproteobacteria,476WV@75682|Oxalobacteraceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_126467_3 1122614.JHZF01000011_gene1718 1.37e-15 74.7 2C7JB@1|root,2ZXVG@2|Bacteria,1P7GB@1224|Proteobacteria,2UYPK@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_126467_8 1031288.AXAA01000003_gene1627 2.97e-06 49.7 2EUFA@1|root,33MXK@2|Bacteria,1VQFP@1239|Firmicutes,24S0X@186801|Clostridia,36N6B@31979|Clostridiaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_126467_9 226185.EF_2318 1.93e-10 63.5 COG0739@1|root,COG0791@1|root,COG0739@2|Bacteria,COG0791@2|Bacteria,1TP24@1239|Firmicutes,4I29P@91061|Bacilli,4B53D@81852|Enterococcaceae 91061|Bacilli M NlpC/P60 family - - - - - - - - - - - - NLPC_P60 k59_126467_11 478749.BRYFOR_08524 5.16e-62 208.0 COG4626@1|root,COG4626@2|Bacteria,1TT9I@1239|Firmicutes,24AFK@186801|Clostridia 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - Terminase_1 k59_211863_2 598467.BrE312_3469 2.02e-31 124.0 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RNE0@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family int - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k59_175052_1 1540097.A0A0A0YRN0_9CAUD 1.83e-63 214.0 4QF3C@10239|Viruses,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_381522_2 525244.HMPREF0023_0080 1.6e-70 231.0 28HEE@1|root,2Z7QU@2|Bacteria,1MXU6@1224|Proteobacteria,1RZSJ@1236|Gammaproteobacteria,3NJ4Z@468|Moraxellaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_381522_3 1445810.A0A0A0PJ06_9CAUD 8.04e-13 68.2 4QGDB@10239|Viruses,4QZHU@35237|dsDNA viruses no RNA stage,4QSG0@28883|Caudovirales,4QHVH@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_175199_4 742740.HMPREF9474_02265 4.79e-49 162.0 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia,222RY@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_126637_7 331869.BAL199_07918 9.11e-06 47.0 2DNV9@1|root,32ZB3@2|Bacteria,1MZGP@1224|Proteobacteria,2UG3I@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_357068_1 105154.Q9MBU6_9VIRU 2.76e-142 424.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_29493_1 1165094.RINTHH_3920 2.64e-14 73.2 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_185523_2 1609634.A0A0C5AFT2_9VIRU 1.57e-112 334.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_185523_5 1609634.A0A0C5ANA6_9VIRU 4.23e-25 104.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_369028_1 1121033.AUCF01000019_gene3705 8.56e-89 273.0 COG0535@1|root,COG0535@2|Bacteria,1N5G8@1224|Proteobacteria,2VB0H@28211|Alphaproteobacteria,2JVSF@204441|Rhodospirillales 204441|Rhodospirillales S Iron-sulfur cluster-binding domain - - - - - - - - - - - - Radical_SAM,SPASM k59_369028_2 1121028.ARQE01000025_gene14 1.55e-51 174.0 COG1442@1|root,COG1442@2|Bacteria,1QH4S@1224|Proteobacteria,2U2NZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria M glycosyl transferase family 8 - - - - - - - - - - - - - k59_256283_2 1235689.K4NWI2_9CAUD 9.09e-10 68.2 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNG7@10744|Podoviridae 10744|Podoviridae S lytic transglycosylase activity - GO:0008150,GO:0016032,GO:0019058,GO:0030260,GO:0039678,GO:0044403,GO:0044409,GO:0044411,GO:0044419,GO:0046718,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0051830,GO:0085027 - - - - - - - - - - - k59_171194_2 1692249.A0A0K1RL40_9CIRC 1.13e-50 176.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_110516_1 1986029.Q9MBM3_9VIRU 1.62e-54 184.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_292819_1 1234888.K0A2J2_9VIRU 2.51e-44 160.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_62106_3 1165094.RINTHH_3920 1.72e-62 207.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_62106_5 105154.Q9MBU6_9VIRU 1.09e-133 406.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_86137_3 1548905.A0A0A1IUN0_9CAUD 9.07e-14 72.8 4QB07@10239|Viruses,4QPGS@28883|Caudovirales,4QMBY@10699|Siphoviridae 10699|Siphoviridae S Domain of unknown function (DUF4326) - - - - - - - - - - - - - k59_62111_1 355246.Q333G3_9CAUD 5.02e-09 63.2 4QGM3@10239|Viruses,4QYG4@35237|dsDNA viruses no RNA stage,4QPTC@28883|Caudovirales,4QMVS@10699|Siphoviridae 10699|Siphoviridae S oxidoreductase activity - - - - - - - - - - - - - k59_256288_3 1502724.FF80_03299 1.27e-67 214.0 COG0175@1|root,COG0175@2|Bacteria 2|Bacteria EH sulfate reduction - - - - - - - - - - - - PAPS_reduct k59_159207_1 553204.CORAM0001_1910 7.68e-36 137.0 COG2304@1|root,COG2304@2|Bacteria 2|Bacteria IU oxidoreductase activity mtsE - - ko:K11089 ko05322,map05322 - - - ko00000,ko00001 - - - TROVE,VWA_2 k59_341240_1 1732201.A0A0N9N7I3_9CIRC 1.32e-31 125.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_281188_1 1385658.U5KPZ6_9VIRU 3.53e-45 163.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_281189_1 633149.Bresu_1398 4.66e-09 60.8 2DSRK@1|root,33H6U@2|Bacteria,1P21N@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_232065_1 1089552.KI911559_gene3672 2.91e-19 100.0 COG2755@1|root,COG2931@1|root,COG3420@1|root,COG4254@1|root,COG2755@2|Bacteria,COG2931@2|Bacteria,COG3420@2|Bacteria,COG4254@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,2JQMP@204441|Rhodospirillales 204441|Rhodospirillales OQ COG2931 RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - HemolysinCabind k59_365541_1 1116369.KB890024_gene2539 6.6e-08 53.5 COG4834@1|root,COG5410@1|root,COG4834@2|Bacteria,COG5410@2|Bacteria,1QWIG@1224|Proteobacteria,2TXBQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Protein conserved in bacteria - - - - - - - - - - - - - k59_195630_1 457398.HMPREF0326_03026 4.18e-54 177.0 2D1GK@1|root,32TAP@2|Bacteria,1QV4T@1224|Proteobacteria,43CXG@68525|delta/epsilon subdivisions,2X85J@28221|Deltaproteobacteria,2MFAA@213115|Desulfovibrionales 28221|Deltaproteobacteria L C-5 cytosine-specific DNA methylase - - - - - - - - - - - - - k59_353812_1 1234888.K0A2J2_9VIRU 8.44e-105 322.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_353812_5 1234888.K0A2J2_9VIRU 1.89e-41 152.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_306272_1 1618248.A0A0C5IB82_9CIRC 1.11e-84 263.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_306381_2 320837.Q4ZCU6_9CAUD 5.66e-63 218.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_294145_4 1517681.HW45_02700 3.17e-42 172.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1QZAD@1224|Proteobacteria,1RYP3@1236|Gammaproteobacteria 1236|Gammaproteobacteria D nuclear chromosome segregation - - - - - - - - - - - - - k59_172671_2 2003327.CAPSD_BPCHP 2.19e-67 232.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_99673_1 1234888.K0A2J2_9VIRU 1.02e-32 131.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_136161_1 1347392.CCEZ01000011_gene2447 3.02e-15 85.5 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,36DTR@31979|Clostridiaceae 186801|Clostridia L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_13908_2 1618248.A0A0C5IB82_9CIRC 1.27e-103 311.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_13908_3 1692242.A0A0K1RKZ2_9CIRC 1.38e-29 115.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_26789_3 247490.KSU1_C1051 1.32e-09 68.6 COG3419@1|root,COG3419@2|Bacteria 2|Bacteria NU Tfp pilus assembly protein tip-associated adhesin pilY1 - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - CarboxypepD_reg,Neisseria_PilC k59_87618_2 1120792.JAFV01000001_gene582 4.13e-38 137.0 2DKVY@1|root,30IDW@2|Bacteria,1RE6Y@1224|Proteobacteria,2U8WV@28211|Alphaproteobacteria 28211|Alphaproteobacteria L YqaJ-like viral recombinase domain - - - - - - - - - - - - YqaJ k59_51126_2 1123034.JMKP01000004_gene1720 2.35e-10 64.7 2CHRY@1|root,30Z9E@2|Bacteria,1RGQK@1224|Proteobacteria,1T1AM@1236|Gammaproteobacteria,3NKV5@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - RecT k59_366699_1 1234888.K0A2J2_9VIRU 2.18e-111 344.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_99676_1 742740.HMPREF9474_01234 1.1e-17 86.7 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,221Y2@1506553|Lachnoclostridium 186801|Clostridia L COG COG0749 DNA polymerase I - 3-5 exonuclease and polymerase domains - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_148161_5 2003327.CAPSD_BPCHP 5.76e-22 99.4 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_282850_1 870967.VIS19158_08213 3.05e-23 105.0 COG0433@1|root,COG0433@2|Bacteria,1QTVP@1224|Proteobacteria,1T1IQ@1236|Gammaproteobacteria,1XY9N@135623|Vibrionales 135623|Vibrionales S Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_282850_3 1122197.ATWI01000011_gene457 1.47e-06 58.2 COG3250@1|root,COG3250@2|Bacteria,1NKEE@1224|Proteobacteria,1SICI@1236|Gammaproteobacteria 1236|Gammaproteobacteria G beta-galactosidase activity - - - - - - - - - - - - - k59_270866_1 1094715.CM001375_gene89 1.52e-06 48.1 COG1551@1|root,COG1551@2|Bacteria,1PD38@1224|Proteobacteria,1T895@1236|Gammaproteobacteria,1JGED@118969|Legionellales 118969|Legionellales T Global regulator protein family - - - - - - - - - - - - CsrA k59_88855_1 691965.D4P7I3_9CAUD 1.72e-128 407.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_161860_5 10855.REP_SPV4 3.3e-30 123.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_161860_7 1385658.U5KPZ6_9VIRU 1.34e-192 555.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_210774_2 626418.bglu_1g12050 6.84e-26 102.0 COG3772@1|root,COG3772@2|Bacteria,1N0ZQ@1224|Proteobacteria,2VVDM@28216|Betaproteobacteria,1K8XQ@119060|Burkholderiaceae 28216|Betaproteobacteria S lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_76573_1 984262.SGRA_0473 3.62e-37 141.0 COG3409@1|root,COG3409@2|Bacteria,4NFKN@976|Bacteroidetes 976|Bacteroidetes M N-acetylmuramidase - - - - - - - - - - - - Muraidase,PG_binding_1 k59_40051_2 1094557.ME3_00391 1.65e-60 202.0 28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria,2U265@28211|Alphaproteobacteria,48T1V@772|Bartonellaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_295637_1 266779.Meso_1199 1.2e-109 332.0 COG0553@1|root,COG0553@2|Bacteria,1R7CK@1224|Proteobacteria,2U228@28211|Alphaproteobacteria,43I7K@69277|Phyllobacteriaceae 28211|Alphaproteobacteria KL DEAD-like helicases superfamily - - - - - - - - - - - - Helicase_C,N6_N4_Mtase k59_89103_1 1234888.K0A2J2_9VIRU 3.6e-51 182.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_210980_1 1397278.AYMV01000039_gene1302 9.7e-06 48.1 COG1476@1|root,COG1476@2|Bacteria,2H0XR@201174|Actinobacteria,4FQHP@85023|Microbacteriaceae 201174|Actinobacteria K Helix-turn-helix domain - - - - - - - - - - - - HTH_3 k59_15213_1 1273125.Rrhod_0713 7.7e-30 115.0 29YHE@1|root,30KCG@2|Bacteria,2I7H4@201174|Actinobacteria,4FZMV@85025|Nocardiaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_4198_1 94122.Shewana3_1812 1.37e-56 199.0 COG0714@1|root,COG0714@2|Bacteria,1PC08@1224|Proteobacteria,1RQ5U@1236|Gammaproteobacteria,2QA3Y@267890|Shewanellaceae 1236|Gammaproteobacteria S PFAM ATPase associated with various cellular activities, AAA_3 - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_5 k59_234742_1 1618248.A0A0C5IB82_9CIRC 7.94e-89 274.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_40053_1 1357399.HMPREF2087_01424 7.54e-07 55.8 COG4227@1|root,COG4227@2|Bacteria,1MU8I@1224|Proteobacteria,42N43@68525|delta/epsilon subdivisions 1224|Proteobacteria L Domain of unknown function (DUF1738) traC - - - - - - - - - - - DUF1738,Toprim_3,Toprim_4 k59_345378_2 1172188.KB911820_gene2847 1.57e-16 78.6 COG3567@1|root,COG3567@2|Bacteria,2H48H@201174|Actinobacteria 201174|Actinobacteria S Phage portal protein, SPP1 Gp6-like - - - - - - - - - - - - Phage_prot_Gp6 k59_345378_3 440250.A5HL29_9CAUD 4.98e-18 79.3 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QPEB@28883|Caudovirales,4QNC3@10744|Podoviridae 10744|Podoviridae S endonuclease activity - - - - - - - - - - - - - k59_66173_1 195105.CN97_00790 1.56e-11 74.3 COG3567@1|root,COG3567@2|Bacteria,1R45U@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF1073) - - - ko:K09961 - - - - ko00000 - - - DUF1073 k59_41363_2 575540.Isop_2448 4.44e-37 129.0 COG3613@1|root,COG3613@2|Bacteria 2|Bacteria F nucleoside 2-deoxyribosyltransferase - - - - - - - - - - - - DUF1937 k59_41363_3 1123269.NX02_21990 3.49e-49 171.0 COG0863@1|root,COG0863@2|Bacteria,1NQ2A@1224|Proteobacteria,2UJ12@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase k59_272405_1 395492.Rleg2_0727 2.15e-21 98.2 COG2268@1|root,COG2268@2|Bacteria,1NT13@1224|Proteobacteria,2U335@28211|Alphaproteobacteria,4BCZZ@82115|Rhizobiaceae 28211|Alphaproteobacteria S Band 7 protein - - - - - - - - - - - - - k59_235789_2 338966.Ppro_0057 3.4e-37 136.0 KOG1584@1|root,32BW5@2|Bacteria,1PW91@1224|Proteobacteria,42YNQ@68525|delta/epsilon subdivisions,2WTQC@28221|Deltaproteobacteria 28221|Deltaproteobacteria H Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_1 k59_212298_2 378806.STAUR_5910 4.3e-08 59.7 COG0863@1|root,COG4123@1|root,COG0863@2|Bacteria,COG4123@2|Bacteria,1NXST@1224|Proteobacteria,43BMK@68525|delta/epsilon subdivisions,2WTFK@28221|Deltaproteobacteria,2Z33Q@29|Myxococcales 28221|Deltaproteobacteria L DNA methylase - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_150964_2 1210884.HG799462_gene9061 3.38e-16 73.9 2EH0T@1|root,33ASV@2|Bacteria 2|Bacteria S VRR-NUC domain - - - - - - - - - - - - VRR_NUC k59_296861_1 1267535.KB906767_gene846 4.7e-05 51.2 COG4796@1|root,COG4796@2|Bacteria,3Y2G2@57723|Acidobacteria,2JHZH@204432|Acidobacteriia 204432|Acidobacteriia U Belongs to the GSP D family - - - ko:K02453 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - Cohesin,Secretin,Secretin_N k59_53907_10 1123487.KB892865_gene1388 3.43e-98 328.0 COG3378@1|root,COG3378@2|Bacteria 2|Bacteria KL Phage plasmid primase P4 family - - - ko:K06919 - - - - ko00000 - - - PriCT_2,Prim-Pol k59_151153_1 313628.LNTAR_25365 1.28e-12 68.6 COG0317@1|root,COG0317@2|Bacteria 2|Bacteria KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance - - 2.7.6.5,3.1.7.2 ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - - HD_4 k59_357503_1 1203550.HMPREF1475_01956 7.95e-06 48.1 COG0863@1|root,COG2189@1|root,COG0863@2|Bacteria,COG2189@2|Bacteria,4NHTG@976|Bacteroidetes,2FQKU@200643|Bacteroidia 976|Bacteroidetes L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571,ko:K07319 - - - - ko00000,ko01000,ko02048 - - - MerR,N6_N4_Mtase k59_16515_7 1609634.A0A0C5AFV4_9VIRU 2.04e-190 551.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_260206_1 105154.Q9MBU6_9VIRU 1.43e-114 347.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_90638_2 1217710.F969_00036 1.22e-127 386.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,1RY0J@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_369459_1 370438.PTH_2144 4.95e-13 74.3 COG0863@1|root,COG1041@1|root,COG0863@2|Bacteria,COG1041@2|Bacteria,1TRDZ@1239|Firmicutes,249ZT@186801|Clostridia,2652N@186807|Peptococcaceae 186801|Clostridia H DNA methylase - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_212524_1 1123508.JH636446_gene6469 1.88e-20 85.5 arCOG06174@1|root,33GGV@2|Bacteria,2J4EE@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_185806_2 224911.27352791 5.42e-13 70.5 COG0817@1|root,COG0817@2|Bacteria,1NDKU@1224|Proteobacteria,2UFCY@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC - 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - - k59_114408_1 1788454.A0A190WHE4_9CIRC 3.06e-41 146.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_104092_1 1303692.SFUL_3690 1.21e-14 74.7 COG0338@1|root,COG0338@2|Bacteria,2IBJA@201174|Actinobacteria 201174|Actinobacteria L D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_274131_3 1265310.CCBD010000081_gene5127 3.12e-08 64.3 COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,2IBWG@201174|Actinobacteria,236HX@1762|Mycobacteriaceae 201174|Actinobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_1 k59_288052_1 489825.LYNGBM3L_53020 4.59e-09 64.3 COG1216@1|root,COG1216@2|Bacteria,1GCKG@1117|Cyanobacteria 1117|Cyanobacteria S Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k59_177292_1 536019.Mesop_3745 2.95e-09 62.8 COG5511@1|root,COG5511@2|Bacteria,1MVN4@1224|Proteobacteria,2TSGI@28211|Alphaproteobacteria,43KZ5@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Phage portal protein, lambda family - - - - - - - - - - - - Phage_portal_2 k59_177292_2 1211114.ALIP01000015_gene270 6.54e-28 123.0 COG0740@1|root,COG3087@1|root,COG0740@2|Bacteria,COG3087@2|Bacteria,1MUQ9@1224|Proteobacteria,1RRQA@1236|Gammaproteobacteria,1X3TK@135614|Xanthomonadales 135614|Xanthomonadales OU Belongs to the peptidase S14 family - - - - - - - - - - - - CLP_protease,Mu-like_gpT k59_358904_1 1335760.ASTG01000033_gene40 1.4e-95 291.0 COG1783@1|root,COG1783@2|Bacteria 2|Bacteria S DNA packaging - - - - - - - - - - - - Terminase_6,Terminase_6C k59_164904_2 691965.D4P7H8_9CAUD 5.05e-14 75.5 4QG1E@10239|Viruses,4QZE1@35237|dsDNA viruses no RNA stage,4QU6Q@28883|Caudovirales,4QMKH@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_347170_1 186617.M9M8L2_9VIRU 1.95e-38 146.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_140733_2 545693.BMQ_3141 2.49e-10 60.5 COG0860@1|root,COG1388@1|root,COG0860@2|Bacteria,COG1388@2|Bacteria,1V3MD@1239|Firmicutes,4HHD1@91061|Bacilli,1ZGHS@1386|Bacillus 91061|Bacilli M Ami_3 - - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,LysM k59_128847_1 1175654.A0A0S0MVN0_9CAUD 5.57e-92 282.0 4QFED@10239|Viruses,4R072@35237|dsDNA viruses no RNA stage,4QPEH@28883|Caudovirales,4QN2V@10699|Siphoviridae 10699|Siphoviridae S tRNA modification - - - - - - - - - - - - - k59_371145_1 742743.HMPREF9453_00390 6.6e-11 63.5 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4H24B@909932|Negativicutes 909932|Negativicutes L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k59_371145_3 490103.B0FIJ6_BPE32 1.1e-16 84.0 4QDGP@10239|Viruses,4QZGF@35237|dsDNA viruses no RNA stage,4QSDY@28883|Caudovirales,4QNCJ@10744|Podoviridae 10744|Podoviridae S ATP binding - - - - - - - - - - - - - k59_17994_1 1498172.A0A0F6N5K2_9CAUD 4.63e-40 153.0 4QBMV@10239|Viruses,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_33618_1 997346.HMPREF9374_2485 2.07e-31 128.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli,27BA0@186824|Thermoactinomycetaceae 91061|Bacilli L DnaB-like helicase C terminal domain dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_33618_2 1235800.C819_02374 2.48e-32 122.0 COG4725@1|root,COG4725@2|Bacteria,1VSNX@1239|Firmicutes,24Q3G@186801|Clostridia,27MZW@186928|unclassified Lachnospiraceae 186801|Clostridia KT MT-A70 - - - - - - - - - - - - MT-A70 k59_312879_2 691965.D4P7L7_9CAUD 1.87e-92 303.0 4QB9J@10239|Viruses,4QXFE@35237|dsDNA viruses no RNA stage,4QS1Z@28883|Caudovirales,4QN8F@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_33744_1 530564.Psta_2445 2.77e-11 58.9 COG1551@1|root,COG1551@2|Bacteria,2J0QX@203682|Planctomycetes 203682|Planctomycetes J Could accelerate the degradation of some genes transcripts potentially through selective RNA binding - - - ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 - - - ko00000,ko00001,ko03019 - - - CsrA k59_142854_2 1333523.L593_09880 7.01e-06 49.3 COG1199@1|root,arCOG00770@2157|Archaea,2XSWZ@28890|Euryarchaeota,23S1B@183963|Halobacteria 183963|Halobacteria K COG1199 Rad3-related DNA helicases - - - - - - - - - - - - DEAD_2,Helicase_C_2 k59_45458_1 326427.Cagg_2273 4.79e-12 76.3 COG0008@1|root,COG1384@1|root,COG0008@2|Bacteria,COG1384@2|Bacteria,2G5WU@200795|Chloroflexi,376W6@32061|Chloroflexia 32061|Chloroflexia J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c k59_239551_2 1609634.A0A0C5AFV4_9VIRU 3.41e-55 190.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_325562_3 626887.J057_01785 1.65e-10 62.8 2DCM2@1|root,32TZV@2|Bacteria,1NAGE@1224|Proteobacteria,1SMRS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_166840_2 869209.Tresu_2648 1.42e-10 58.2 2A6AJ@1|root,30V37@2|Bacteria,2J9E5@203691|Spirochaetes 203691|Spirochaetes S Protein of unknown function (DUF2997) - - - - - - - - - - - - DUF2997 k59_166840_4 339860.Msp_1550 1.98e-97 311.0 COG0464@1|root,arCOG01308@2157|Archaea,2Y2E2@28890|Euryarchaeota,23PGB@183925|Methanobacteria 183925|Methanobacteria O ATPase family associated with various cellular activities (AAA) - - - - - - - - - - - - AAA k59_70103_1 398578.Daci_3441 9.26e-06 52.8 2EFFY@1|root,3398P@2|Bacteria 2|Bacteria S Prophage minor tail protein Z (GPZ) - - - - - - - - - - - - Minor_tail_Z k59_290368_1 1336243.JAEA01000002_gene2650 1.16e-18 78.6 COG0209@1|root,COG0209@2|Bacteria,1N0E3@1224|Proteobacteria,2UQM4@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Ribonucleotide reductase, barrel domain - - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - Ribonuc_red_lgC k59_156902_2 1131462.DCF50_p1388 1.9e-25 111.0 2C377@1|root,2Z7II@2|Bacteria,1V1QQ@1239|Firmicutes,24ETZ@186801|Clostridia 186801|Clostridia S P22 coat protein - gene protein 5 - - - - - - - - - - - - P22_CoatProtein k59_181340_1 2003327.CAPSD_BPCHP 5.88e-18 90.5 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_181340_5 105154.Q9MBU0_9VIRU 6.44e-27 114.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_181340_7 1234888.K0A2J2_9VIRU 5.26e-88 277.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_21451_2 525255.HMPREF0077_0836 6.44e-11 67.8 COG0732@1|root,COG0732@2|Bacteria,1V24U@1239|Firmicutes,24EH7@186801|Clostridia,22IN1@1570339|Peptoniphilaceae 186801|Clostridia V Type I restriction modification DNA specificity domain - - 3.1.21.3 ko:K01154 - - - - ko00000,ko01000,ko02048 - - - Methylase_S k59_59220_1 1219035.NT2_13_00580 6.61e-46 167.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_132693_1 592316.Pat9b_2114 5.7e-15 82.8 COG1511@1|root,COG1511@2|Bacteria,1QWV3@1224|Proteobacteria,1T4UM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S tail tape measure protein - - - - - - - - - - - - - k59_230138_2 1788454.A0A190WHE4_9CIRC 1.87e-52 181.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_277775_1 1029823.AFIE01000007_gene1908 0.000402 47.0 29WEM@1|root,30I0C@2|Bacteria,1QV42@1224|Proteobacteria,1T27I@1236|Gammaproteobacteria,3NMCG@468|Moraxellaceae 1236|Gammaproteobacteria S Helix-turn-helix domain - - - - - - - - - - - - HTH_36 k59_303004_2 1540097.A0A0A0YWA1_9CAUD 1.09e-08 60.1 4QCT5@10239|Viruses,4QTPG@28883|Caudovirales,4QNK2@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_189508_1 1385658.U5KPZ6_9VIRU 1.33e-118 359.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_21456_2 1416009.V9VCY0_9CAUD 1.99e-21 93.2 4QD56@10239|Viruses,4QY23@35237|dsDNA viruses no RNA stage,4QS8U@28883|Caudovirales,4QNR8@10744|Podoviridae 10744|Podoviridae S nucleic acid binding - - - - - - - - - - - - - k59_107802_2 1296416.JACB01000017_gene5220 5.28e-26 105.0 COG0107@1|root,COG0107@2|Bacteria,4NM6U@976|Bacteroidetes,1I1G9@117743|Flavobacteriia,2YJDG@290174|Aquimarina 976|Bacteroidetes E Histidine biosynthesis protein - - - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth k59_168495_1 4641.GSMUA_Achr11P13660_001 2.61e-80 273.0 28HK1@1|root,2QPXS@2759|Eukaryota,37NXW@33090|Viridiplantae,3GF00@35493|Streptophyta,3KSZH@4447|Liliopsida 35493|Streptophyta L Toprim domain - GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0004003,GO:0004386,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016043,GO:0016070,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032392,GO:0032508,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051276,GO:0055086,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090407,GO:0097159,GO:0097747,GO:0140097,GO:0140098,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_4 k59_277969_1 1034769.KB910518_gene4197 6.32e-25 99.0 2DMNG@1|root,32SP1@2|Bacteria,1VAXC@1239|Firmicutes,4HM1Q@91061|Bacilli,26ZFG@186822|Paenibacillaceae 91061|Bacilli S COG NOG14552 non supervised orthologous group - - - - - - - - - - - - - k59_265396_2 1081640.AGFU01000049_gene794 2.54e-10 67.8 COG3756@1|root,COG3756@2|Bacteria,1RFD3@1224|Proteobacteria,2VGAE@28211|Alphaproteobacteria,2K78F@204457|Sphingomonadales 204457|Sphingomonadales S Protein of unknown function (DUF1376) - - - - - - - - - - - - DUF1376 k59_364079_2 742740.HMPREF9474_02271 3.28e-137 407.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia,221RR@1506553|Lachnoclostridium 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_364079_3 691965.D4P7C5_9CAUD 7.92e-309 854.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_364079_8 411460.RUMTOR_01353 1.9e-20 85.9 2CGGA@1|root,345NF@2|Bacteria,1VZU0@1239|Firmicutes,253ZW@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_364079_10 172088.AUGA01000072_gene7109 1.21e-14 85.1 COG5164@1|root,COG5164@2|Bacteria,1N2ZN@1224|Proteobacteria 1224|Proteobacteria K regulation of DNA-templated transcription, elongation - - - - - - - - - - - - Collagen k59_388366_4 1385658.U5KPZ6_9VIRU 4.24e-124 380.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_191503_1 948071.S4S2T1_9CAUD 4.9e-59 205.0 4QHPY@10239|Viruses,4QWIA@35237|dsDNA viruses no RNA stage,4QSXS@28883|Caudovirales,4QNJ2@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_24100_7 12336.Q331V6_CBCP 3.02e-05 52.0 4QAPV@10239|Viruses,4QV7H@35237|dsDNA viruses no RNA stage,4QPC3@28883|Caudovirales,4QINS@10662|Myoviridae 10662|Myoviridae S DNA binding - - - - - - - - - - - - - k59_388373_5 1379718.S5TMX4_9CIRC 8.46e-21 97.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_24122_3 189753.AXAS01000008_gene6703 2.83e-08 60.1 COG3409@1|root,COG3926@1|root,COG3409@2|Bacteria,COG3926@2|Bacteria,1MVXW@1224|Proteobacteria,2TT3H@28211|Alphaproteobacteria,3K0NK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Predicted Peptidoglycan domain - - - ko:K17733 - - - - ko00000,ko01000,ko01002,ko01011 - - - Glyco_hydro_108,PG_binding_1,PG_binding_3,VanY k59_24130_2 1618248.A0A0C5IB82_9CIRC 2.76e-23 98.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_364410_2 643648.Slip_1827 6.97e-41 145.0 2C585@1|root,338E0@2|Bacteria,1VUPX@1239|Firmicutes,250IR@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_316286_7 2003327.REP_BPCHP 3.32e-08 63.2 4QCVK@10239|Viruses,4QUMV@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_316286_10 2003327.CAPSD_BPCHP 2.3e-28 125.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_219158_1 428125.CLOLEP_01411 2.09e-58 197.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia,3WNJZ@541000|Ruminococcaceae 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_219158_2 691965.D4P7D6_9CAUD 3.58e-26 114.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_304165_1 1234888.K0A2J2_9VIRU 8.25e-45 161.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_328455_2 1394176.AWUO01000014_gene644 2.34e-16 81.6 2BWS4@1|root,32XQ0@2|Bacteria,2GR3P@201174|Actinobacteria,4D1S1@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - k59_255402_2 264462.Bd2582 6.54e-07 56.2 COG2911@1|root,COG3210@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,1NED3@1224|Proteobacteria,42WDX@68525|delta/epsilon subdivisions,2MTVC@213481|Bdellovibrionales,2WRDH@28221|Deltaproteobacteria 213481|Bdellovibrionales U cell wall surface anchor family protein - - - - - - - - - - - - Peptidase_S74 k59_291940_1 1121456.ATVA01000014_gene632 2.46e-43 155.0 COG1783@1|root,COG1783@2|Bacteria,1RAGC@1224|Proteobacteria,42Z29@68525|delta/epsilon subdivisions,2WTUP@28221|Deltaproteobacteria,2MCJK@213115|Desulfovibrionales 28221|Deltaproteobacteria S phage Terminase large subunit - - - - - - - - - - - - - k59_158359_1 1453505.JASY01000036_gene3902 0.000426 46.6 COG2374@1|root,COG4932@1|root,COG2374@2|Bacteria,COG4932@2|Bacteria,4PKCH@976|Bacteroidetes,1IJQJ@117743|Flavobacteriia 976|Bacteroidetes M Protein conserved in bacteria - - - - - - - - - - - - CHU_C,DUF11,OmpA,SprB k59_328463_1 471854.Dfer_0352 6.91e-05 50.8 COG2755@1|root,COG3391@1|root,COG2755@2|Bacteria,COG3391@2|Bacteria,4PN20@976|Bacteroidetes,47TKQ@768503|Cytophagia 976|Bacteroidetes E Carbohydrate esterase, sialic acid-specific acetylesterase - - - - - - - - - - - - SASA k59_340478_13 1121033.AUCF01000004_gene4632 1.13e-06 57.4 COG2227@1|root,COG2227@2|Bacteria,1RAQ6@1224|Proteobacteria,2U62S@28211|Alphaproteobacteria,2JWU8@204441|Rhodospirillales 204441|Rhodospirillales H Methyltransferase domain - - - - - - - - - - - - Methyltransf_23 k59_231175_1 1692255.A0A0K1RL52_9CIRC 8.16e-17 84.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_219660_2 1692256.A0A0K1RL85_9CIRC 1.32e-66 215.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_134284_1 742725.HMPREF9450_02123 1.06e-52 197.0 COG1196@1|root,COG1196@2|Bacteria,4NMBI@976|Bacteroidetes,2FR6N@200643|Bacteroidia 976|Bacteroidetes D nuclear chromosome segregation - - - - - - - - - - - - - k59_122309_1 1609634.A0A0C5AFV4_9VIRU 5.88e-132 395.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_37167_2 1127692.HMPREF9075_02379 6.92e-69 223.0 COG0270@1|root,COG0270@2|Bacteria,4NVMZ@976|Bacteroidetes,1IEAJ@117743|Flavobacteriia,1EQWM@1016|Capnocytophaga 976|Bacteroidetes L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_255829_3 105154.Q9MBU0_9VIRU 1.12e-46 167.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_85763_1 1609634.A0A0C5AFT2_9VIRU 2.97e-77 244.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_255943_2 1089111.G8I7S6_9CAUD 6.34e-13 67.4 4QAV0@10239|Viruses,4QY41@35237|dsDNA viruses no RNA stage,4QSR9@28883|Caudovirales,4QKWJ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_49495_1 511.JT27_18230 8.76e-86 276.0 2F26G@1|root,33V4S@2|Bacteria,1NUS1@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_73801_1 626887.J057_01665 8.42e-105 338.0 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,1RR0M@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_146722_2 105154.Q9MBU2_9VIRU 3.64e-14 73.2 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_170879_1 1463841.JOIR01000004_gene6130 8.77e-11 66.6 COG1652@1|root,COG1652@2|Bacteria 2|Bacteria S positive regulation of growth rate ygaU GO:0003674,GO:0005488,GO:0008150,GO:0010035,GO:0010038,GO:0030955,GO:0031420,GO:0035864,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896 - ko:K21687 - - - - ko00000 - GH23 - BON,LysM,Transglycosylas k59_110209_1 105154.Q9MBU0_9VIRU 5.34e-19 90.5 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_243726_3 1126885.I3VYX0_9CAUD 6e-10 60.1 4QG21@10239|Viruses,4QYV7@35237|dsDNA viruses no RNA stage,4QRQT@28883|Caudovirales,4QM3S@10699|Siphoviridae 10699|Siphoviridae S Phage terminase large subunit - - - - - - - - - - - - - k59_328979_1 1165094.RINTHH_3920 4.9e-23 100.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_255945_1 216594.MMAR_3451 3.36e-14 75.1 COG1409@1|root,COG1409@2|Bacteria,2GRKX@201174|Actinobacteria,236UU@1762|Mycobacteriaceae 201174|Actinobacteria S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - - - - - - - - - - Metallophos,Metallophos_2 k59_855_2 645099.MREP_BBTVA 1.94e-12 74.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_316753_2 105154.Q9MBU0_9VIRU 9.39e-23 103.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_316753_3 2003327.CAPSD_BPCHP 1.89e-21 96.3 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_207532_3 1609634.A0A0C5AFV4_9VIRU 6.6e-223 631.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_195240_1 696281.Desru_1076 5.95e-20 90.9 28J2E@1|root,2Z8YX@2|Bacteria,1TRF9@1239|Firmicutes,249U3@186801|Clostridia 186801|Clostridia S Protein of unknown function (DUF2815) - - - - - - - - - - - - DUF2815 k59_340977_1 1070319.CAGGBEG34_190022 2.3e-09 63.5 COG3723@1|root,COG3723@2|Bacteria,1R6DB@1224|Proteobacteria,2VNV4@28216|Betaproteobacteria,1K7AD@119060|Burkholderiaceae 28216|Betaproteobacteria L PFAM RecT protein recT - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_182840_1 1692244.A0A0K1RLR5_9CIRC 1.27e-49 168.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_147464_1 1524880.A0A076G697_9VIRU 0.00064 47.4 4QD1M@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_305671_1 1564096.A0A0A0YVJ4_9CAUD 1.82e-30 120.0 4QHG7@10239|Viruses,4QRS2@28883|Caudovirales,4QJX5@10662|Myoviridae 10662|Myoviridae S PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - - k59_317926_1 1125863.JAFN01000001_gene3090 8.32e-09 57.8 COG1734@1|root,COG1734@2|Bacteria,1N8RB@1224|Proteobacteria,42W5H@68525|delta/epsilon subdivisions,2WSAD@28221|Deltaproteobacteria 28221|Deltaproteobacteria T RNA polymerase-binding protein DksA dksA - - ko:K06204 ko02026,map02026 - - - ko00000,ko00001,ko03000,ko03009,ko03021 - - - zf-dskA_traR k59_62775_1 691965.D4P7D6_9CAUD 6.04e-191 562.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_62775_4 742740.HMPREF9474_02267 3.87e-82 251.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia,221N8@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_62775_5 1537917.JU82_06570 6.84e-56 181.0 2CGG9@1|root,2ZVSJ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_62775_6 691965.D4P7D9_9CAUD 8.89e-44 155.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_147553_1 311424.DhcVS_33 7.29e-09 56.6 COG0194@1|root,COG0194@2|Bacteria,2G6EW@200795|Chloroflexi,34D78@301297|Dehalococcoidia 301297|Dehalococcoidia F Essential for recycling GMP and indirectly, cGMP gmk - 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin k59_147553_2 1122132.AQYH01000005_gene637 8e-38 149.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,2TQQ8@28211|Alphaproteobacteria,4B7MU@82115|Rhizobiaceae 28211|Alphaproteobacteria M penicillin-binding protein pbpC - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase k59_329955_1 1265845.PWEIH_00500 2.23e-18 85.1 28MC2@1|root,2ZAQD@2|Bacteria,1VSEU@1239|Firmicutes,4HT1S@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k59_208612_1 105154.Q9MBU6_9VIRU 6.7e-06 48.5 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_208612_3 145579.REP_BPPHM 3.4e-13 75.5 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_354281_1 240016.ABIZ01000001_gene310 1.34e-17 88.2 COG4122@1|root,COG4122@2|Bacteria 2|Bacteria E O-methyltransferase activity - - - - - - - - - - - - Methyltransf_24 k59_354281_3 1197719.A464_2019 4.95e-33 129.0 COG0740@1|root,COG0740@2|Bacteria,1MUQ9@1224|Proteobacteria,1RRQA@1236|Gammaproteobacteria 1236|Gammaproteobacteria OU Belongs to the peptidase S14 family - - - - - - - - - - - - CLP_protease k59_354281_4 1461579.CCNK01000031_gene1097 2.1e-34 142.0 COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,1RPB0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S portal protein - - - - - - - - - - - - Phage_portal k59_354281_5 1005048.CFU_3368 1.98e-16 84.3 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2VNHP@28216|Betaproteobacteria,478Q0@75682|Oxalobacteraceae 28216|Betaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_14005_11 1471542.A0A023ZWF6_9CAUD 1.58e-12 74.7 4QM6C@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_14005_13 716928.AJQT01000006_gene2795 4.23e-29 112.0 COG0791@1|root,COG0791@2|Bacteria,1N19W@1224|Proteobacteria,2UD6N@28211|Alphaproteobacteria,4BMUC@82115|Rhizobiaceae 28211|Alphaproteobacteria M NLP P60 protein - - - - - - - - - - - - - k59_14005_15 351016.RAZWK3B_16805 1.25e-32 128.0 2C2XN@1|root,32GT6@2|Bacteria,1REZE@1224|Proteobacteria,2U8HW@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM ERF family protein - - - - - - - - - - - - ERF k59_14005_17 319224.Sputcn32_0640 4e-35 128.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,2Q8X8@267890|Shewanellaceae 1236|Gammaproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363,GO:1901576 - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_14005_19 1235689.K4NZ61_9CAUD 1.92e-09 59.3 4QAQA@10239|Viruses,4QXB8@35237|dsDNA viruses no RNA stage,4QQ03@28883|Caudovirales,4QNPC@10744|Podoviridae 10744|Podoviridae S NinB protein - - - - - - - - - - - - - k59_172800_1 1609634.A0A0C5AFV4_9VIRU 1.37e-42 154.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_111928_2 156889.Mmc1_1690 7.03e-128 386.0 COG1783@1|root,COG1783@2|Bacteria,1MVJB@1224|Proteobacteria,2U2BM@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_233545_2 445972.ANACOL_02159 3.1e-08 61.2 COG1215@1|root,COG1216@1|root,COG2227@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,COG2227@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia,3WHZS@541000|Ruminococcaceae 186801|Clostridia M Glycosyltransferase, group 2 family protein - - - ko:K20444 - - - - ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 - Glycos_transf_2 k59_294323_1 1217710.F969_00036 9.51e-47 169.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,1RY0J@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_197171_1 751945.Theos_2083 1.33e-24 107.0 COG0358@1|root,COG4643@1|root,COG0358@2|Bacteria,COG4643@2|Bacteria,1WK40@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L Toprim domain - - - - - - - - - - - - Toprim_3 k59_245462_3 1120936.KB907208_gene1108 1.44e-96 297.0 COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4EGN4@85012|Streptosporangiales 201174|Actinobacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - - - - - - - - - - RecA k59_209677_2 1236501.BAJU01000072_gene3212 1.14e-95 282.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2TU8N@28211|Alphaproteobacteria,2JXEZ@204441|Rhodospirillales 204441|Rhodospirillales L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_160851_1 1200557.JHWV01000001_gene275 5.31e-10 65.1 28HPK@1|root,2Z7XJ@2|Bacteria,1UZP3@1239|Firmicutes,4H2MM@909932|Negativicutes 909932|Negativicutes S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_342824_5 1457393.AZ09_10465 2.23e-47 160.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2TU8N@28211|Alphaproteobacteria,2JXEZ@204441|Rhodospirillales 204441|Rhodospirillales L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_197235_1 666681.M301_0132 4.66e-29 121.0 2D784@1|root,32TNH@2|Bacteria,1N098@1224|Proteobacteria,2VX0M@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_27082_1 1140.Synpcc7942_0725 1.79e-115 352.0 COG1061@1|root,COG1061@2|Bacteria,1G2HP@1117|Cyanobacteria,1H08U@1129|Synechococcus 1117|Cyanobacteria L Helicase conserved C-terminal domain - - - - - - - - - - - - DUF3427,Helicase_C,ResIII k59_27082_4 310539.Q5G7P7_9CAUD 9.02e-08 57.8 4QGB5@10239|Viruses,4QXR2@35237|dsDNA viruses no RNA stage,4QSQD@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_27082_5 90371.CY43_09840 2.5e-27 119.0 2DBI5@1|root,2Z9EN@2|Bacteria,1PMHG@1224|Proteobacteria,1RQE1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Exodeoxyribonuclease VIII - - - ko:K10906 - - - - ko00000,ko01000,ko03400 - - - DUF3799 k59_27082_7 1304878.AUGD01000009_gene6429 1.62e-32 133.0 COG3723@1|root,COG3723@2|Bacteria,1R6DB@1224|Proteobacteria,2U82T@28211|Alphaproteobacteria,3K2R8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L RecT family - - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_306635_1 1392490.JHZX01000001_gene963 5.37e-18 91.3 COG1475@1|root,COG1475@2|Bacteria,4NHT0@976|Bacteroidetes,1HZJ4@117743|Flavobacteriia 976|Bacteroidetes K Belongs to the ParB family - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_294366_1 1414737.V9QJ75_9CAUD 1.33e-05 53.1 4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019058,GO:0019062,GO:0022610,GO:0039638,GO:0044403,GO:0044406,GO:0044419,GO:0044423,GO:0044650,GO:0051704,GO:0098015,GO:0098024 - - - - - - - - - - - k59_379410_2 1280944.HY17_04705 6.1e-15 84.0 2E8SI@1|root,3333B@2|Bacteria,1N7MG@1224|Proteobacteria,2UJSF@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_295465_5 1141137.K4F7V9_9CAUD 0.000147 50.4 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QP39@10744|Podoviridae 10744|Podoviridae S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_284393_1 1463854.JOHT01000033_gene2588 2.59e-10 65.9 COG0863@1|root,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - 2.1.1.72 ko:K00571,ko:K07319 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_343894_2 1472912.A0A023NGC4_9CAUD 1.55e-08 53.9 4QAQV@10239|Viruses,4QUPK@35237|dsDNA viruses no RNA stage,4QPCB@28883|Caudovirales 28883|Caudovirales S protein disulfide oxidoreductase activity - - - - - - - - - - - - - k59_76621_1 691965.D4P7L7_9CAUD 1.18e-219 645.0 4QB9J@10239|Viruses,4QXFE@35237|dsDNA viruses no RNA stage,4QS1Z@28883|Caudovirales,4QN8F@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_258772_1 1123247.AUIJ01000002_gene2243 2.8e-49 166.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2TU8N@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_246651_1 1234888.K0A2J2_9VIRU 2.27e-103 324.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_380393_2 1327036.R4JHP8_9CAUD 3.63e-09 65.1 4QCEF@10239|Viruses,4QVWZ@35237|dsDNA viruses no RNA stage,4QTBA@28883|Caudovirales,4QMGR@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_332290_2 234621.RER_25240 4.41e-17 79.3 2DYV8@1|root,32V63@2|Bacteria,2GRK5@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_332290_14 1187851.A33M_4269 2.27e-09 56.2 COG3514@1|root,COG3514@2|Bacteria,1N7KA@1224|Proteobacteria,2UGW1@28211|Alphaproteobacteria 28211|Alphaproteobacteria S BrnA antitoxin of type II toxin-antitoxin system - - - - - - - - - - - - BrnA_antitoxin k59_332290_28 268739.Nmlp_2675 7.63e-19 97.1 COG4983@1|root,arCOG06276@2157|Archaea,2XUG1@28890|Euryarchaeota,23SRM@183963|Halobacteria 183963|Halobacteria L Phage plasmid primase, P4 - - - ko:K06919 - - - - ko00000 - - - - k59_332290_30 926560.KE387023_gene2268 1.13e-22 95.5 COG4712@1|root,COG4712@2|Bacteria,1WIU2@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Rad52 22 double-strand break repair protein ddrA GO:0001101,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009269,GO:0009314,GO:0009414,GO:0009415,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010212,GO:0010332,GO:0031668,GO:0033554,GO:0034641,GO:0042221,GO:0042631,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070887,GO:0071214,GO:0071229,GO:0071462,GO:0071465,GO:0071478,GO:0071479,GO:0071480,GO:0071496,GO:0071704,GO:0090304,GO:0104004,GO:1901360,GO:1901700,GO:1901701 - - - - - - - - - - Rad52_Rad22 k59_271116_1 145579.CAPSD_BPPHM 2.61e-31 126.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_284640_1 56780.SYN_03204 2.46e-27 110.0 COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2WMUI@28221|Deltaproteobacteria,2MQH5@213462|Syntrophobacterales 28221|Deltaproteobacteria L TIGRFAM hydrolase, TatD family tatD - - ko:K03424 - - - - ko00000,ko01000 - - - Fer4_14,Radical_SAM,TatD_DNase k59_162082_1 1524882.A0A076G6H8_9CAUD 2.38e-112 342.0 4QC8M@10239|Viruses,4QQU8@28883|Caudovirales,4QM0A@10699|Siphoviridae 10699|Siphoviridae S Protein of unknown function (DUF1073) - - - - - - - - - - - - - k59_162082_2 195105.CN97_00795 5.8e-149 433.0 COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria 28211|Alphaproteobacteria S ATP-binding protein' - - - - - - - - - - - - Terminase_3,Terminase_6,Terminase_6C k59_15227_2 351348.Maqu_1500 2.5e-06 52.0 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RMJ1@1236|Gammaproteobacteria,465VD@72275|Alteromonadaceae 1236|Gammaproteobacteria L Arm DNA-binding domain - - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k59_76836_2 1385658.U5KPZ6_9VIRU 4.12e-48 172.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_125778_2 1156919.QWC_17152 4.17e-07 51.6 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2VTZX@28216|Betaproteobacteria,3T4AD@506|Alcaligenaceae 28216|Betaproteobacteria G lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_184897_1 742740.HMPREF9474_02262 5.23e-12 72.4 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,221IX@1506553|Lachnoclostridium 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_380600_1 626887.J057_01665 2.25e-41 155.0 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,1RR0M@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_333409_1 1273125.Rrhod_0707 1.59e-33 131.0 2ANQ2@1|root,31DPJ@2|Bacteria,2I9V0@201174|Actinobacteria,4G8YR@85025|Nocardiaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_212318_2 1313304.CALK_0081 5.16e-10 61.6 COG0566@1|root,COG0566@2|Bacteria 2|Bacteria J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family - - 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind k59_357342_1 1408428.JNJP01000009_gene1355 1.11e-16 78.2 COG3108@1|root,COG3108@2|Bacteria,1NCZX@1224|Proteobacteria,42VTQ@68525|delta/epsilon subdivisions,2WMR2@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k59_212320_1 91604.ID47_02960 2.41e-46 161.0 28HS3@1|root,2Z7ZE@2|Bacteria,1QH9A@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_41398_2 1123322.KB904687_gene4986 0.000551 47.4 COG4122@1|root,COG4122@2|Bacteria,2GQ0Z@201174|Actinobacteria 201174|Actinobacteria S Methyltransferase domain - - - - - - - - - - - - Methyltransf_24 k59_185710_1 1609634.A0A0C5AFV4_9VIRU 2.56e-199 572.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_78090_2 329381.D9ICX0_9CAUD 1.17e-14 82.8 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QI82@10662|Myoviridae 10662|Myoviridae S virus tail, fiber - - - - - - - - - - - - - k59_138800_1 298653.Franean1_5323 7.37e-24 106.0 COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria,4ESP4@85013|Frankiales 201174|Actinobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_3,Phage_integrase k59_369304_6 1123321.KB905821_gene4242 1.69e-47 171.0 2BMCR@1|root,32FWY@2|Bacteria,2GZKQ@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_114429_2 1609634.A0A0C5AFV4_9VIRU 1.52e-126 384.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_67597_2 156889.Mmc1_1716 4.44e-51 172.0 28NGF@1|root,2ZBII@2|Bacteria,1R9KY@1224|Proteobacteria,2U1P7@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_128439_1 1609634.A0A0C5AFV4_9VIRU 1.6e-53 186.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_43061_10 136084.Q9G0F7_9CAUD 1.42e-88 300.0 4QH2I@10239|Viruses,4QWWD@35237|dsDNA viruses no RNA stage,4QQE9@28883|Caudovirales,4QNFX@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_43061_16 213236.Q716M6_9CAUD 7.02e-06 55.8 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_67740_2 525245.HMPREF0044_1105 5.24e-12 71.6 COG0467@1|root,COG3378@1|root,COG0467@2|Bacteria,COG3378@2|Bacteria,2H1DT@201174|Actinobacteria 201174|Actinobacteria T Phage plasmid primase, P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,PriCT_1,Prim-Pol k59_186643_3 105154.Q9MBU0_9VIRU 1.2e-52 182.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_186643_5 145579.H_BPPHM 1.88e-05 52.4 4QCA6@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_186643_6 2003327.CAPSD_BPCHP 2.71e-75 249.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_6868_1 1410628.JNKS01000023_gene1763 1.56e-18 88.2 COG0270@1|root,COG0270@2|Bacteria,1UDJE@1239|Firmicutes,25IAY@186801|Clostridia,27S1J@186928|unclassified Lachnospiraceae 186801|Clostridia L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_310656_2 714961.BFZC1_09565 2.7e-05 47.4 COG0270@1|root,COG0270@2|Bacteria,1TS3G@1239|Firmicutes,4HC1I@91061|Bacilli,3IYQF@400634|Lysinibacillus 91061|Bacilli H C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase,HTH_3 k59_140456_1 1165094.RINTHH_3920 3.08e-27 111.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_17763_1 115417.EPrPW00000014670 7.91e-09 62.8 COG3914@1|root,KOG4626@2759|Eukaryota,1MCNY@121069|Pythiales 121069|Pythiales GOT TPR Domain containing protein. Source PGD - - - - - - - - - - - - - k59_300737_3 1609634.A0A0C5AFT2_9VIRU 8.07e-40 143.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_324942_1 115711.CP_0543 2.83e-23 95.5 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_44838_2 1454010.JEOE01000073_gene2 4.7e-48 164.0 2DP06@1|root,33008@2|Bacteria,2GTMC@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_179142_4 28369.VG55_BPMD2 1.2e-12 71.2 4QAV0@10239|Viruses,4QY41@35237|dsDNA viruses no RNA stage,4QSR9@28883|Caudovirales,4QKWJ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_33200_1 55601.VANGNB10_cI1598c 1.88e-31 114.0 2DNA4@1|root,32WDI@2|Bacteria,1RH8K@1224|Proteobacteria,1S8YN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage tail tube, TTP, lambda-like - - - - - - - - - - - - Phage_TTP_11 k59_239063_1 438753.AZC_0843 7.15e-41 147.0 28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria,2U265@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_57042_2 443152.MDG893_20669 2.9e-36 129.0 COG3772@1|root,COG3772@2|Bacteria,1N0ZQ@1224|Proteobacteria,1S9AE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_289768_1 351627.Csac_1450 1.82e-25 110.0 COG3723@1|root,COG3723@2|Bacteria,1V3B6@1239|Firmicutes,24HHQ@186801|Clostridia,42HHM@68295|Thermoanaerobacterales 186801|Clostridia L recombination protein Bet bet - - - - - - - - - - - RecT k59_94379_1 1429046.RR21198_0302 1.43e-07 57.0 2EC0B@1|root,335ZK@2|Bacteria,2I86C@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_117408_1 796620.VIBC2010_19925 1.73e-29 121.0 COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,1RN7C@1236|Gammaproteobacteria,1XW4M@135623|Vibrionales 135623|Vibrionales S AAA domain (dynein-related subfamily) cobS - 6.6.1.2 ko:K09882 ko00860,ko01100,map00860,map01100 - R05227 RC02000 ko00000,ko00001,ko01000 - - - AAA_5,CbbQ_C,CobS_N k59_348950_2 584708.Apau_1083 5.52e-76 239.0 COG0037@1|root,COG0037@2|Bacteria 2|Bacteria D tRNA processing tilS - 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C k59_324948_1 1166018.FAES_1810 5.02e-35 132.0 COG0863@1|root,COG0863@2|Bacteria,4PP8R@976|Bacteroidetes 976|Bacteroidetes L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_154728_1 1472912.A0A023NGU4_9CAUD 2.56e-08 62.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019058,GO:0019062,GO:0022610,GO:0039638,GO:0044403,GO:0044406,GO:0044419,GO:0044423,GO:0044650,GO:0051704,GO:0098015,GO:0098024 - - - - - - - - - - - k59_384614_1 313612.L8106_22826 1.38e-30 119.0 COG4422@1|root,COG4422@2|Bacteria,1G1Q2@1117|Cyanobacteria,1HA22@1150|Oscillatoriales 1117|Cyanobacteria S COG4422 Bacteriophage protein gp37 - - - - - - - - - - - - DUF5131 k59_325148_7 1385658.U5KNR1_9VIRU 4.15e-58 194.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_360446_2 443152.MDG893_20594 9e-45 150.0 2DNB5@1|root,32WIW@2|Bacteria,1N0BM@1224|Proteobacteria,1S8UT@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacteriophage HK97-gp10, putative tail-component - - - - - - - - - - - - HK97-gp10_like k59_81737_1 105154.Q9MBU6_9VIRU 1.72e-102 314.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_217669_2 1234888.K0A2R8_9VIRU 3.54e-33 125.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_277142_1 1279017.AQYJ01000026_gene5 1.28e-19 82.4 2AD08@1|root,312N7@2|Bacteria,1NDC4@1224|Proteobacteria,1SAPT@1236|Gammaproteobacteria,467W0@72275|Alteromonadaceae 1236|Gammaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_291051_3 910964.GEAM_4248 3.15e-10 72.4 COG1196@1|root,COG1196@2|Bacteria,1MU81@1224|Proteobacteria,1RS6P@1236|Gammaproteobacteria 1236|Gammaproteobacteria D tail length tape measure - - - - - - - - - - - - TMP_2,Tape_meas_lam_C k59_96185_1 502025.Hoch_0231 2.86e-16 85.5 COG2425@1|root,COG2425@2|Bacteria,1N1RQ@1224|Proteobacteria,42Z19@68525|delta/epsilon subdivisions,2WZHK@28221|Deltaproteobacteria,2Z261@29|Myxococcales 28221|Deltaproteobacteria S von Willebrand factor (vWF) type A domain - - - - - - - - - - - - VWA_CoxE k59_71187_1 1862825.A0A193CE78_9VIRU 6.69e-19 87.8 4QAZA@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_107411_1 1236508.BAKF01000055_gene2399 4.21e-35 141.0 COG3941@1|root,COG3941@2|Bacteria,4NRSR@976|Bacteroidetes 976|Bacteroidetes D nuclear chromosome segregation - - - - - - - - - - - - - k59_21127_1 1247726.MIM_c10800 6.4e-19 92.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2VNHP@28216|Betaproteobacteria,3T3DM@506|Alcaligenaceae 28216|Betaproteobacteria S COG4626 Phage terminase-like protein, large subunit - - - - - - - - - - - - Terminase_1 k59_156498_1 1123288.SOV_4c02780 1.75e-64 224.0 COG0503@1|root,COG0553@1|root,COG2263@1|root,COG3846@1|root,COG0503@2|Bacteria,COG0553@2|Bacteria,COG2263@2|Bacteria,COG3846@2|Bacteria,1TSYQ@1239|Firmicutes,4H5A6@909932|Negativicutes 909932|Negativicutes F protein secretion by the type IV secretion system - - - - - - - - - - - - SLT k59_338781_1 1163398.AJJP01000172_gene939 3.65e-34 121.0 2DNA4@1|root,32WDI@2|Bacteria,1RH8K@1224|Proteobacteria,1S8YN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage tail tube, TTP, lambda-like - - - - - - - - - - - - Phage_TTP_11 k59_338781_2 443152.MDG893_20574 1.32e-42 143.0 2CHRA@1|root,32S6D@2|Bacteria,1MZ8I@1224|Proteobacteria,1SHSQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage tail assembly chaperone, TAC - - - - - - - - - - - - Phage_TAC_13 k59_291209_1 338966.Ppro_3121 5.65e-13 71.2 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,42N7I@68525|delta/epsilon subdivisions,2WJG8@28221|Deltaproteobacteria,43TS1@69541|Desulfuromonadales 28221|Deltaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k59_254444_1 1234888.K0A2J2_9VIRU 8.06e-141 419.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_48136_1 1692244.A0A0K1RLR5_9CIRC 2.99e-28 114.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_363318_1 421052.F945_01954 8.31e-10 65.9 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,1RZ7H@1236|Gammaproteobacteria,3NMFD@468|Moraxellaceae 1236|Gammaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_278657_2 665956.HMPREF1032_00668 8.3e-48 157.0 2AIHK@1|root,318ZG@2|Bacteria,1V7P0@1239|Firmicutes,24KNU@186801|Clostridia,3WNH7@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_120426_1 1038867.AXAY01000004_gene2382 5.98e-27 119.0 COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,2TU4W@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_11292_1 551895.B5AX37_9CAUD 3.85e-37 145.0 4QGM3@10239|Viruses,4QYG4@35237|dsDNA viruses no RNA stage,4QPTC@28883|Caudovirales,4QJW3@10662|Myoviridae 10662|Myoviridae S Pfam:Terminase_6C - - - - - - - - - - - - - k59_60396_1 438753.AZC_3589 9.06e-61 206.0 COG0209@1|root,COG0209@2|Bacteria,1N0E3@1224|Proteobacteria,2UQM4@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Ribonucleotide reductase, barrel domain - - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - Ribonuc_red_lgC k59_315480_1 1788454.A0A190WHE4_9CIRC 2.37e-33 128.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_120431_1 460265.Mnod_2611 9.99e-34 130.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria,1JXFW@119045|Methylobacteriaceae 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_351971_1 1788444.A0A190WHB9_9CIRC 2.38e-12 65.9 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_351971_2 1788444.A0A190WHB9_9CIRC 6.01e-47 162.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_327981_1 1286171.EAL2_c10940 4.96e-14 70.5 COG1694@1|root,COG1694@2|Bacteria,1VIQA@1239|Firmicutes,24SKH@186801|Clostridia 186801|Clostridia S MazG nucleotide pyrophosphohydrolase - - - - - - - - - - - - MazG k59_327981_4 1500281.JQKZ01000050_gene4139 3.64e-14 78.2 COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,1HXPM@117743|Flavobacteriia,3ZNI6@59732|Chryseobacterium 976|Bacteroidetes L DNA-directed DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon k59_72753_1 1609634.A0A0C5AFV4_9VIRU 1.27e-96 303.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_145651_1 1385658.U5KPZ6_9VIRU 9.49e-84 265.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_72761_1 1609634.A0A0C5ANA6_9VIRU 1.39e-19 91.3 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_72761_2 1609634.A0A0C5AFV4_9VIRU 1.27e-23 99.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_37207_2 488538.SAR116_0377 8.34e-51 189.0 COG4373@1|root,COG4373@2|Bacteria 2|Bacteria - - gp17a - - ko:K06909 - - - - ko00000 - - - Terminase_6,Terminase_6C k59_304581_1 1217720.ALOX01000106_gene1193 1.14e-11 65.1 28IJ1@1|root,2Z8K0@2|Bacteria,1R5PC@1224|Proteobacteria,2U0RA@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_316691_1 443152.MDG893_20574 3.46e-22 90.5 2CHRA@1|root,32S6D@2|Bacteria,1MZ8I@1224|Proteobacteria,1SHSQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage tail assembly chaperone, TAC - - - - - - - - - - - - Phage_TAC_13 k59_316691_2 211586.SO_2956 7.32e-26 101.0 2DNA4@1|root,32WDI@2|Bacteria,1RH8K@1224|Proteobacteria,1S8YN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage tail tube, TTP, lambda-like - - - - - - - - - - - - Phage_TTP_11 k59_37211_2 1229755.K7R2J6_9CAUD 1.17e-21 102.0 4QASV@10239|Viruses,4QWD9@35237|dsDNA viruses no RNA stage,4QQ4N@28883|Caudovirales 28883|Caudovirales S recA bacterial DNA recombination protein - - - - - - - - - - - - - k59_243772_1 1429912.V5R9A1_9CAUD 8.41e-07 58.5 4QB4T@10239|Viruses,4QYFG@35237|dsDNA viruses no RNA stage,4QR7K@28883|Caudovirales,4QN2T@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_182876_2 1618248.A0A0C5IB82_9CIRC 7.09e-13 75.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_37310_1 439235.Dalk_1042 1.43e-07 59.7 COG1216@1|root,COG4122@1|root,COG1216@2|Bacteria,COG4122@2|Bacteria,1N2AR@1224|Proteobacteria,42R09@68525|delta/epsilon subdivisions,2WMWB@28221|Deltaproteobacteria 28221|Deltaproteobacteria G Methyltransferase domain - - - - - - - - - - - - Methyltransf_24 k59_317985_1 445688.E3SNL6_9CAUD 5.57e-24 111.0 4QGP7@10239|Viruses,4QQ0Q@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_281877_1 694060.D2K0B8_9CAUD 1.55e-17 92.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QI32@10662|Myoviridae 10662|Myoviridae S DNA polymerase family A - - - - - - - - - - - - - k59_147723_1 4792.ETI31775 3.24e-66 225.0 2C7RP@1|root,2SPXE@2759|Eukaryota 2759|Eukaryota - - - - - - - - - - - - - - - k59_330156_1 1609634.A0A0C5AFV4_9VIRU 3.84e-51 179.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_183529_3 1201035.KE007212_gene1396 2.29e-07 57.8 COG3756@1|root,COG3756@2|Bacteria,1QYEJ@1224|Proteobacteria,2UKMJ@28211|Alphaproteobacteria,48TGW@772|Bartonellaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1376) - - - - - - - - - - - - DUF1376 k59_26106_1 1692248.A0A0K1RLN2_9CIRC 3.75e-36 133.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_86928_2 1618248.A0A0C5IB82_9CIRC 5.72e-12 72.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_38261_1 1609634.A0A0C5AFV4_9VIRU 1.15e-66 224.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_123649_5 1234888.K0A2J2_9VIRU 7.85e-85 273.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_366222_1 291112.PAU_03137 5.43e-14 69.7 2CAZB@1|root,2Z9VC@2|Bacteria,1R89D@1224|Proteobacteria,1RPMA@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - AAA_24 k59_99115_3 1385658.U5KNR1_9VIRU 5.84e-48 168.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_99115_5 1385658.U5KPZ6_9VIRU 9.27e-175 510.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_99115_6 105154.Q9MBU3_9VIRU 3.26e-14 76.6 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_208838_2 477974.Daud_1778 3.27e-12 68.9 COG1086@1|root,COG1086@2|Bacteria,1TPTC@1239|Firmicutes,247YC@186801|Clostridia,261P4@186807|Peptococcaceae 186801|Clostridia M PFAM polysaccharide biosynthesis protein pseB - 4.2.1.115,5.1.3.2 ko:K15894,ko:K17716 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00362 R00291,R09697 RC00289,RC02609 ko00000,ko00001,ko00002,ko01000 - - - Polysacc_synt_2 k59_343155_7 388399.SSE37_25383 1.12e-36 130.0 2DQ7M@1|root,3354I@2|Bacteria,1QZPB@1224|Proteobacteria,2TYBB@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage tail tube protein - - - - - - - - - - - - Phage_tail_2 k59_210109_3 1609634.A0A0C5AFT2_9VIRU 4.69e-31 123.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_197533_1 2003327.REP_BPCHP 3.73e-05 53.5 4QCVK@10239|Viruses,4QUMV@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_3321_3 1609634.A0A0C5AFV4_9VIRU 3.09e-269 750.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_3321_4 1609634.A0A0C5ANA6_9VIRU 1.38e-29 113.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_136643_1 1385658.U5KPZ6_9VIRU 6.06e-42 156.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_51743_2 28358.Q9MBK0_9CAUD 1.24e-09 65.5 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - GO:0003674,GO:0003824,GO:0005575,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019012,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 - - - - - - - - - - - k59_294766_1 105154.Q9MBU6_9VIRU 3.5e-92 286.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_3324_1 633149.Bresu_1402 2.96e-44 149.0 COG3108@1|root,COG3108@2|Bacteria,1RICX@1224|Proteobacteria,2UDAG@28211|Alphaproteobacteria,2KJH3@204458|Caulobacterales 204458|Caulobacterales S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Peptidase_M15_4 k59_355524_3 77856.REP_BFDV 1.91e-40 151.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_294768_1 1187851.A33M_3329 2.41e-49 171.0 2C5GI@1|root,2Z8C1@2|Bacteria,1R8XM@1224|Proteobacteria,2TUME@28211|Alphaproteobacteria 28211|Alphaproteobacteria S P22 coat protein - gene protein 5 - - - - - - - - - - - - P22_CoatProtein k59_136652_1 1211777.BN77_4166 5.99e-42 157.0 COG3170@1|root,COG3170@2|Bacteria,1QVEE@1224|Proteobacteria,2TWDG@28211|Alphaproteobacteria,4BHSG@82115|Rhizobiaceae 28211|Alphaproteobacteria NU Phage P22-like portal protein - - - - - - - - - - - - P22_portal k59_148928_1 742733.HMPREF9469_05020 1.52e-125 437.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,221IX@1506553|Lachnoclostridium 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_148928_2 1537917.JU82_09980 5.29e-24 96.3 2ARVA@1|root,31H70@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - HK97-gp10_like k59_148928_5 742733.HMPREF9469_05026 3.75e-58 190.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia,221N8@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_148928_8 691965.D4P7D6_9CAUD 4.05e-126 399.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_148928_9 428125.CLOLEP_01411 7.92e-22 96.3 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia,3WNJZ@541000|Ruminococcaceae 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_222308_1 438753.AZC_3598 2.22e-36 137.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT52@1224|Proteobacteria,2TVNI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_2 k59_125070_1 313596.RB2501_01415 6.11e-141 413.0 COG1061@1|root,COG2093@1|root,COG1061@2|Bacteria,COG2093@2|Bacteria,4NECV@976|Bacteroidetes,1HXAD@117743|Flavobacteriia 976|Bacteroidetes L Domain of unknown function (DUF3427) - - - - - - - - - - - - Helicase_C,ResIII k59_125070_2 445970.ALIPUT_01612 3.36e-90 280.0 COG0270@1|root,COG0270@2|Bacteria,4NJPP@976|Bacteroidetes,2FKYT@200643|Bacteroidia 976|Bacteroidetes H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_125070_3 1327974.S0A0U7_9CAUD 1.21e-47 173.0 4QCHV@10239|Viruses,4QUW9@35237|dsDNA viruses no RNA stage,4QQEZ@28883|Caudovirales,4QMEA@10699|Siphoviridae 10699|Siphoviridae S Virulence-associated protein E - - - - - - - - - - - - - k59_367387_1 1185766.DL1_19620 4.47e-29 108.0 COG3409@1|root,COG3409@2|Bacteria,1RAYU@1224|Proteobacteria,2U6D1@28211|Alphaproteobacteria 28211|Alphaproteobacteria M N-acetylmuramidase - - - - - - - - - - - - Muraidase,PG_binding_1 k59_113556_2 1165094.RINTHH_3920 5.6e-37 138.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_223412_1 684719.HIMB114_00009450 9.47e-08 61.2 COG4547@1|root,COG4547@2|Bacteria,1MX11@1224|Proteobacteria,2TS4N@28211|Alphaproteobacteria,4BPRN@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria H Cobalamin biosynthesis protein CobT cobT - 6.6.1.2 ko:K09883 ko00860,ko01100,map00860,map01100 - R05227 RC02000 ko00000,ko00001,ko01000 - - - CobT,CobT_C k59_185166_2 1235661.K0IK54_9CAUD 9.37e-08 59.3 4QDZP@10239|Viruses,4R039@35237|dsDNA viruses no RNA stage,4QSG5@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_29026_4 761193.Runsl_4413 6.49e-08 58.2 COG0338@1|root,COG0338@2|Bacteria,4NRXP@976|Bacteroidetes 976|Bacteroidetes L DNA N-6-adenine-methyltransferase (Dam) - - - - - - - - - - - - Dam k59_285310_1 742918.D4N3P2_9CIRC 9.49e-12 71.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_4734_1 1458697.W6EKG4_9CAUD 6.07e-13 70.9 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QM2K@10699|Siphoviridae 10699|Siphoviridae S Phage Tail Collar Domain - - - - - - - - - - - - - k59_247394_2 195105.CN97_04315 4.35e-06 53.1 COG3740@1|root,COG3740@2|Bacteria,1N2D8@1224|Proteobacteria,2UD3U@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Phage prohead protease, HK97 family - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78 k59_4736_1 1088721.NSU_0767 3.99e-09 63.5 2EG1N@1|root,339TN@2|Bacteria,1NEFY@1224|Proteobacteria,2UGTQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S prophage protein Bartonella henselae str. Houston-1 gi 49237922 emb CAF27125.1 - - - - - - - - - - - - - k59_320811_1 1609634.A0A0C5ANA6_9VIRU 1.02e-14 78.2 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_53137_1 1609634.A0A0C5AFV4_9VIRU 4.74e-207 592.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_235279_1 1609634.A0A0C5AFT2_9VIRU 1.21e-65 212.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_30599_4 105154.Q9MBT9_9VIRU 9.35e-09 54.3 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_164070_2 237727.NAP1_00795 6.27e-54 179.0 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2UG3A@28211|Alphaproteobacteria,2KCE6@204457|Sphingomonadales 204457|Sphingomonadales G Phage lysozyme - - - - - - - - - - - - Phage_lysozyme k59_30600_1 1476391.X5L0Y2_9CAUD 5.19e-40 146.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_346209_3 1123489.AUAN01000002_gene671 2.46e-06 55.8 COG3935@1|root,COG3935@2|Bacteria,1VHH7@1239|Firmicutes,4H5YT@909932|Negativicutes 909932|Negativicutes L DnaD domain protein - - - - - - - - - - - - - k59_103309_1 1618248.A0A0C5IB82_9CIRC 7.81e-48 166.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_334228_2 243233.MCA2930 1.99e-14 75.9 COG5301@1|root,COG5301@2|Bacteria,1NDIE@1224|Proteobacteria,1SFIF@1236|Gammaproteobacteria 1236|Gammaproteobacteria G cellulose 1,4-beta-cellobiosidase activity - - - - - - - - - - - - - k59_176406_1 105154.Q9MBU3_9VIRU 1.77e-17 82.8 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_176406_2 1986029.Q9MBM8_9VIRU 7.48e-16 76.6 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_358065_2 331869.BAL199_22387 3e-12 65.1 COG0582@1|root,COG0582@2|Bacteria,1RD46@1224|Proteobacteria,2U7Q0@28211|Alphaproteobacteria,4BSQ5@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria L COG0582 Integrase - - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_integrase k59_236551_1 472759.Nhal_3989 1.56e-38 140.0 28H9R@1|root,2Z7MD@2|Bacteria,1MVTR@1224|Proteobacteria,1RMPH@1236|Gammaproteobacteria,1X2QH@135613|Chromatiales 135613|Chromatiales S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_42303_2 991905.SL003B_0918 1.11e-33 133.0 COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,2TQNG@28211|Alphaproteobacteria,4BPWK@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N k59_115065_1 428125.CLOLEP_03521 3.5e-11 64.3 COG4712@1|root,COG4712@2|Bacteria,1VENV@1239|Firmicutes,25DT0@186801|Clostridia,3WMEW@541000|Ruminococcaceae 186801|Clostridia S Rad52/22 family double-strand break repair protein - - - - - - - - - - - - Rad52_Rad22 k59_200420_2 1304275.C41B8_05408 5.26e-47 162.0 2DVPY@1|root,33WQ8@2|Bacteria,1N9VQ@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_17019_1 794846.AJQU01000075_gene3388 1.39e-35 129.0 2CK39@1|root,32SBG@2|Bacteria,1MZ6F@1224|Proteobacteria,2UBT5@28211|Alphaproteobacteria,4BCFY@82115|Rhizobiaceae 28211|Alphaproteobacteria S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 k59_186234_4 566461.SSFG_01013 5.02e-65 216.0 COG0438@1|root,COG0438@2|Bacteria,2HH27@201174|Actinobacteria 201174|Actinobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 k59_176407_1 105154.Q9MBU6_9VIRU 2.11e-128 385.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_176407_5 1165094.RINTHH_3920 9.32e-72 231.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_249021_1 1122599.AUGR01000001_gene288 2.23e-50 167.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,1SQ0T@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_274808_1 1223545.GS4_51_00120 1.84e-35 131.0 2CJW6@1|root,32SAX@2|Bacteria,2ISQ9@201174|Actinobacteria,4GGDY@85026|Gordoniaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_104704_2 1692244.A0A0K1RLR5_9CIRC 5.06e-83 257.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_18511_1 744980.TRICHSKD4_0700 9.33e-74 232.0 COG3772@1|root,COG3772@2|Bacteria 2|Bacteria S cytolysis by virus of host cell - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_226902_1 1219035.NT2_16_00120 5.52e-09 60.8 COG1196@1|root,COG1196@2|Bacteria 2|Bacteria D nuclear chromosome segregation - - - - - - - - - - - - Cytochrome_C554,Dam,FIVAR,Multi-haem_cyto,PhageMin_Tail k59_56067_3 479433.Caci_7461 3.5e-10 70.1 COG3979@1|root,COG4934@1|root,COG3979@2|Bacteria,COG4934@2|Bacteria 2|Bacteria O collagen metabolic process - - 3.2.1.14,3.2.1.4 ko:K01179,ko:K01183 ko00500,ko00520,ko01100,map00500,map00520,map01100 - R01206,R02334,R06200,R11307,R11308 RC00467 ko00000,ko00001,ko01000 - GH18,GH5,GH9 - CBM_5_12,Glyco_hydro_18,He_PIG,fn3 k59_141241_1 1197951.I6RT34_9CAUD 9.35e-154 449.0 4QGAG@10239|Viruses,4R0KB@35237|dsDNA viruses no RNA stage,4QUA4@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_347946_1 1692249.A0A0K1RLN8_9CIRC 2.01e-20 92.4 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_371673_1 1498011.A0A096XUU5_9CAUD 1e-43 158.0 4QAUT@10239|Viruses,4QQ7X@28883|Caudovirales,4QNET@10744|Podoviridae 10744|Podoviridae S DNA ligase (ATP) activity - - - - - - - - - - - - - k59_215167_1 926564.KI911577_gene479 1.52e-16 77.8 COG5492@1|root,COG5492@2|Bacteria,2IK71@201174|Actinobacteria 201174|Actinobacteria N domain, Protein - - - - - - - - - - - - - k59_202191_1 351160.RCIX2617 1.04e-07 58.2 COG0863@1|root,arCOG00115@2157|Archaea,2XT30@28890|Euryarchaeota,2NAWJ@224756|Methanomicrobia 224756|Methanomicrobia L to Modification methylase in Methanococcus jannaschii (Q58392) and Methanobacterium thermoformicicum (P29568) - - 2.1.1.113,2.1.1.72 ko:K00571,ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_44072_1 46429.BV95_02394 1.12e-08 63.9 COG3598@1|root,COG3598@2|Bacteria,1R4EA@1224|Proteobacteria,2U8VM@28211|Alphaproteobacteria 28211|Alphaproteobacteria L AAA domain - - - - - - - - - - - - AAA_25,DnaB,Prim-Pol k59_359712_1 1027292.HMPREF9372_1263 7.91e-57 197.0 COG4626@1|root,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,4HAXI@91061|Bacilli,26GFD@186818|Planococcaceae 91061|Bacilli S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_80731_1 1081640.AGFU01000065_gene3708 1.35e-66 210.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2TU8N@28211|Alphaproteobacteria,2K409@204457|Sphingomonadales 204457|Sphingomonadales L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_32399_2 1266925.JHVX01000006_gene2058 4.61e-19 81.6 2DSDE@1|root,33FMS@2|Bacteria,1NJ0C@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_348138_5 251221.35211274 9.85e-16 79.3 COG4712@1|root,COG4712@2|Bacteria 2|Bacteria S DNA recombination - - - - - - - - - - - - Rad52_Rad22 k59_348138_6 1005395.CSV86_06221 3.35e-20 89.7 2E5K5@1|root,330BC@2|Bacteria,1RG8X@1224|Proteobacteria,1S3Z1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Siphovirus Gp157 - - - - - - - - - - - - Sipho_Gp157 k59_348138_7 38033.XP_001221915.1 2.8e-07 55.8 COG0445@1|root,KOG2311@2759|Eukaryota,38BWB@33154|Opisthokonta,3NUU9@4751|Fungi,3QJZZ@4890|Ascomycota,211WM@147550|Sordariomycetes,3U4Y1@5139|Sordariales,3HF88@35718|Chaetomiaceae 4751|Fungi J GidA associated domain 3 MTO1 GO:0000166,GO:0000959,GO:0000963,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0030488,GO:0032259,GO:0032543,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043414,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0070525,GO:0070899,GO:0070900,GO:0071704,GO:0090304,GO:0090646,GO:0097159,GO:0140053,GO:1900864,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K03495,ko:K12479 ko04138,ko04144,map04138,map04144 - R08701 RC00053,RC00209,RC00870 ko00000,ko00001,ko03016,ko03036,ko04131 - - - GIDA,GIDA_assoc k59_262478_1 1297581.H919_10118 1.98e-22 102.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,21VBU@150247|Anoxybacillus 91061|Bacilli L DNA polymerase alpha chain like domain dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k59_276602_1 652103.Rpdx1_2951 6.23e-25 107.0 COG3064@1|root,COG3064@2|Bacteria,1R6JV@1224|Proteobacteria,2U5NE@28211|Alphaproteobacteria,3JTDC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Membrane - - - - - - - - - - - - - k59_228884_2 1219035.NT2_13_00580 1.17e-18 87.8 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_313304_1 575540.Isop_2441 3.26e-45 151.0 2CEI6@1|root,2ZED5@2|Bacteria,2J3S1@203682|Planctomycetes 203682|Planctomycetes S Protein of unknown function (DUF669) - - - - - - - - - - - - DUF669 k59_313304_2 575540.Isop_2440 1.43e-66 213.0 28HHC@1|root,2Z7T2@2|Bacteria,2J15Z@203682|Planctomycetes 203682|Planctomycetes S AAA domain - - - - - - - - - - - - AAA_24 k59_180183_5 1121406.JAEX01000037_gene733 1.32e-12 70.1 COG1948@1|root,COG1948@2|Bacteria,1R6ZP@1224|Proteobacteria,43BE0@68525|delta/epsilon subdivisions,2X6SI@28221|Deltaproteobacteria,2MH69@213115|Desulfovibrionales 28221|Deltaproteobacteria L ERCC4 domain - - - - - - - - - - - - ERCC4 k59_180183_6 1123322.KB904659_gene1021 5.63e-12 73.9 COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria 201174|Actinobacteria L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k59_45911_2 349520.PPE_03839 2.79e-15 81.6 COG1216@1|root,COG1216@2|Bacteria,1V5RV@1239|Firmicutes,4HIMX@91061|Bacilli,26TUK@186822|Paenibacillaceae 91061|Bacilli S glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k59_228885_1 1336243.JAEA01000002_gene2645 1.39e-05 46.2 28PTM@1|root,2ZCEU@2|Bacteria,1R5DD@1224|Proteobacteria,2TVG7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_228885_4 488538.SAR116_0371 5.29e-44 152.0 2CBYP@1|root,33HT7@2|Bacteria,1NJP6@1224|Proteobacteria,2UN9N@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_9215_1 1192759.AKIB01000023_gene2907 3.02e-22 103.0 COG0553@1|root,COG0827@1|root,COG3087@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG3087@2|Bacteria,COG4646@2|Bacteria,1PGZG@1224|Proteobacteria,2TVEU@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DEAD-like helicases superfamily - - - - - - - - - - - - Helicase_C,N6_Mtase,ResIII,SNF2_N k59_361213_2 323261.Noc_1974 1.84e-16 80.5 COG0823@1|root,COG0823@2|Bacteria,1R4CN@1224|Proteobacteria,1S0NH@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - PD40 k59_313460_1 1082932.ATCR1_06741 3.93e-62 206.0 COG5323@1|root,COG5323@2|Bacteria,1R049@1224|Proteobacteria 1224|Proteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6 k59_361216_1 1268068.PG5_42330 9.58e-47 166.0 COG4386@1|root,COG4386@2|Bacteria,1MXZD@1224|Proteobacteria,1RN4Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria N Tail sheath protein - - - - - - - - - - - - Phage_sheath_1,Phage_sheath_1C k59_303396_2 443143.GM18_1664 4.37e-09 60.5 COG0744@1|root,COG4932@1|root,COG0744@2|Bacteria,COG4932@2|Bacteria 2|Bacteria M domain protein mrcB - 2.4.1.129,3.4.16.4 ko:K05365,ko:K05366,ko:K20276,ko:K21464 ko00550,ko01100,ko01501,ko02024,map00550,map01100,map01501,map02024 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,UB2H k59_157414_2 1618256.A0A0C5IM93_9CIRC 2.85e-21 98.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_315102_1 105154.Q9MBU6_9VIRU 9.06e-59 200.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_327705_1 382640.BT_0457 8.53e-26 120.0 COG4643@1|root,COG4643@2|Bacteria,1N08G@1224|Proteobacteria,2U9N8@28211|Alphaproteobacteria,48SYH@772|Bartonellaceae 28211|Alphaproteobacteria S membrane spanning protein Brucella melitensis 16M gi 17987979 ref - - - - - - - - - - - - DUF3987 k59_181834_3 1609634.A0A0C5ANA6_9VIRU 1.74e-20 92.8 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_230715_2 1502851.FG93_01933 9.6e-54 215.0 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2TV2W@28211|Alphaproteobacteria,3JW1G@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S COG4733 Phage-related protein, tail component - - - - - - - - - - - - Phage-tail_3 k59_230715_6 1096546.WYO_4119 2.43e-15 79.3 COG5281@1|root,COG5281@2|Bacteria,1R47M@1224|Proteobacteria,2TUIV@28211|Alphaproteobacteria,1JV0F@119045|Methylobacteriaceae 28211|Alphaproteobacteria S COG5281, Phage-related minor tail protein - - - - - - - - - - - - - k59_168939_1 428125.CLOLEP_01413 2.81e-31 113.0 2E2Y0@1|root,32XYV@2|Bacteria,1VD9S@1239|Firmicutes,24PK0@186801|Clostridia,3WPDR@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_278382_1 670252.C8CLI5_9CAUD 8.36e-35 143.0 4QCM6@10239|Viruses,4QVAQ@35237|dsDNA viruses no RNA stage,4QPVV@28883|Caudovirales,4QNID@10744|Podoviridae 10744|Podoviridae S actin binding - - - - - - - - - - - - - k59_278382_2 78245.Xaut_3704 1.42e-154 451.0 COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,3EYR8@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_47760_1 426114.THI_1948 6.99e-52 181.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2VNHP@28216|Betaproteobacteria 28216|Betaproteobacteria S Terminase - - - - - - - - - - - - Terminase_1 k59_315110_2 1379725.S5SYG4_9CIRC 2.13e-14 79.7 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_49009_1 105154.Q9MBU6_9VIRU 2.12e-21 93.6 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_340468_2 768706.Desor_0348 0.000376 43.5 COG2089@1|root,COG2089@2|Bacteria,1TS09@1239|Firmicutes,249DN@186801|Clostridia,2614N@186807|Peptococcaceae 186801|Clostridia M SAF domain neuB - 2.5.1.101,2.5.1.56 ko:K01654,ko:K18430 ko00520,ko01100,map00520,map01100 - R01804,R04435,R10304 RC00159 ko00000,ko00001,ko01000 - - - NeuB,SAF k59_316264_1 156889.Mmc1_1716 0.000106 50.8 28NGF@1|root,2ZBII@2|Bacteria,1R9KY@1224|Proteobacteria,2U1P7@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_316264_3 1211115.ALIQ01000188_gene655 3.5e-152 466.0 28MS5@1|root,2ZB0J@2|Bacteria,1PTV9@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_316264_4 1156919.QWC_12533 8.58e-81 263.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,2VM59@28216|Betaproteobacteria,3T7Q0@506|Alcaligenaceae 28216|Betaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_146139_4 1242864.D187_000285 1.24e-56 183.0 COG4422@1|root,COG4422@2|Bacteria,1MXQI@1224|Proteobacteria,42NZ6@68525|delta/epsilon subdivisions,2WKPZ@28221|Deltaproteobacteria,2YWD6@29|Myxococcales 28221|Deltaproteobacteria S Pfam:Gp37_Gp68 - - - - - - - - - - - - DUF5131 k59_291911_2 1123503.KB908056_gene1316 7.93e-05 50.1 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TRIQ@28211|Alphaproteobacteria,2KF7K@204458|Caulobacterales 204458|Caulobacterales M Belongs to the DegT DnrJ EryC1 family - - - - - - - - - - - - DegT_DnrJ_EryC1 k59_61109_1 1986029.Q9MBM8_9VIRU 8.95e-42 151.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_61109_2 105154.Q9MBU3_9VIRU 6.38e-10 59.3 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_377039_3 1347392.CCEZ01000011_gene2447 1.4e-43 156.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,36DTR@31979|Clostridiaceae 186801|Clostridia L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_61142_1 186617.M9M8L2_9VIRU 9.97e-30 126.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_121827_1 438753.AZC_3592 2.88e-42 148.0 COG0258@1|root,COG0258@2|Bacteria,1MYSI@1224|Proteobacteria,2U60N@28211|Alphaproteobacteria 28211|Alphaproteobacteria L 5'-3' exonuclease, N-terminal resolvase-like domain - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc_N k59_121827_4 1282876.BAOK01000002_gene600 8.69e-28 115.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS19@28211|Alphaproteobacteria,4BP86@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdZ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k59_194815_1 582345.D6RRL4_BPKPP 2.62e-50 174.0 4QARC@10239|Viruses,4QV4E@35237|dsDNA viruses no RNA stage,4QPDS@28883|Caudovirales,4QIV1@10662|Myoviridae 10662|Myoviridae S nucleic acid binding - - - - - - - - - - - - - k59_291943_2 525368.HMPREF0591_4797 3.91e-14 71.6 2DYV8@1|root,32V63@2|Bacteria,2GRK5@201174|Actinobacteria,23EHA@1762|Mycobacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_219163_1 1609634.A0A0C5AFV4_9VIRU 4.95e-44 165.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_146162_1 2003327.CAPSD_BPCHP 3.89e-17 90.1 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_146162_4 913970.F8RW84_9VIRU 3.08e-08 62.4 4QCVK@10239|Viruses,4QUMV@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_316594_25 163164.WD_1012 1.28e-18 95.9 COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,2TT33@28211|Alphaproteobacteria,47EUP@766|Rickettsiales 766|Rickettsiales S Phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_316594_29 1232436.CAPF01000054_gene164 1.16e-60 212.0 COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria,4CUUP@84998|Coriobacteriia 84998|Coriobacteriia L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_316594_36 999550.KI421507_gene2208 4.08e-16 80.5 2DPEC@1|root,331RJ@2|Bacteria,1N7D6@1224|Proteobacteria,2UFU5@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_316594_46 378806.STAUR_3110 6.4e-07 58.5 COG3409@1|root,COG3409@2|Bacteria,1N9AN@1224|Proteobacteria,42XYC@68525|delta/epsilon subdivisions,2WSN6@28221|Deltaproteobacteria,2YZQ1@29|Myxococcales 28221|Deltaproteobacteria M Putative peptidoglycan binding domain - - - ko:K17733 - - - - ko00000,ko01000,ko01002,ko01011 - - - PG_binding_1,VanY k59_316594_48 1391647.AVSV01000028_gene177 2e-07 54.7 COG0860@1|root,COG3409@1|root,COG0860@2|Bacteria,COG3409@2|Bacteria,1V7G8@1239|Firmicutes,248ER@186801|Clostridia,36E0H@31979|Clostridiaceae 186801|Clostridia M N-acetylmuramoyl-L-alanine amidase - - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,PG_binding_1,SH3_3 k59_231583_1 1986029.Q9MBM8_9VIRU 1.24e-61 207.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_243575_1 759938.F5BSB4_9CIRC 1.52e-20 95.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_219721_1 1692255.A0A0K1RL52_9CIRC 3.06e-85 265.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_195209_11 530564.Psta_0658 1.34e-49 184.0 COG5362@1|root,COG5362@2|Bacteria,2J0FK@203682|Planctomycetes 203682|Planctomycetes S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_195209_13 1437603.BMON_0140 0.000101 53.5 2C9AC@1|root,2Z7TR@2|Bacteria,2I07F@201174|Actinobacteria,4D2I2@85004|Bifidobacteriales 201174|Actinobacteria S Phage portal protein, SPP1 Gp6-like - - - - - - - - - - - - Phage_prot_Gp6 k59_195209_23 67267.JNXT01000054_gene2989 5.61e-17 94.7 2F1HE@1|root,33UHX@2|Bacteria,2IH41@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_195209_33 1121864.OMO_01316 1.26e-60 235.0 COG5283@1|root,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,4HEHJ@91061|Bacilli 91061|Bacilli D Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_195209_44 317936.Nos7107_2133 9.99e-09 62.8 COG3409@1|root,COG3409@2|Bacteria,1GIYB@1117|Cyanobacteria,1HT7U@1161|Nostocales 1117|Cyanobacteria M Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_1 k59_366034_1 105154.Q9MBU0_9VIRU 1.37e-37 140.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_111112_1 428125.CLOLEP_01417 7.96e-29 112.0 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia,3WMXK@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_111112_2 742740.HMPREF9474_02263 1.08e-24 97.4 2ARVA@1|root,31H70@2|Bacteria,1V7JT@1239|Firmicutes,24JPE@186801|Clostridia,222RD@1506553|Lachnoclostridium 186801|Clostridia S Bacteriophage HK97-gp10, putative tail-component - - - - - - - - - - - - HK97-gp10_like k59_329916_1 1005994.GTGU_04125 3.47e-25 99.8 COG3409@1|root,COG3409@2|Bacteria,1R4RS@1224|Proteobacteria,1S346@1236|Gammaproteobacteria 1236|Gammaproteobacteria M CHAP domain - - - - - - - - - - - - CHAP k59_281763_3 28377.ENSACAP00000004404 1.94e-22 97.4 KOG2401@1|root,KOG2401@2759|Eukaryota,3A0U0@33154|Opisthokonta,3BPQY@33208|Metazoa,3CSD1@33213|Bilateria,47Z8J@7711|Chordata,498H2@7742|Vertebrata 33208|Metazoa L AAA domain N4BP2L1 - - - - - - - - - - - AAA_33 k59_111113_1 1234888.K0A2R8_9VIRU 9.14e-46 158.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_38088_1 1618248.A0A0C5IB82_9CIRC 4.5e-16 82.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_305654_1 1121456.ATVA01000015_gene2512 2.11e-05 48.1 2C9JF@1|root,32RPD@2|Bacteria,1N8CG@1224|Proteobacteria,42REW@68525|delta/epsilon subdivisions,2WNQ1@28221|Deltaproteobacteria,2MB30@213115|Desulfovibrionales 28221|Deltaproteobacteria S ERF superfamily - - - - - - - - - - - - ERF k59_135247_3 1556290.A0A0A0RM00_9CAUD 5.51e-44 160.0 4QAXQ@10239|Viruses,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_25939_1 1692253.A0A0K1RLM4_9CIRC 1.76e-22 99.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_98932_2 1177928.TH2_05253 1.14e-13 73.6 COG1511@1|root,COG3941@1|root,COG1511@2|Bacteria,COG3941@2|Bacteria 2|Bacteria O tape measure - - - - - - - - - - - - DUF4175,TMP_2,Tape_meas_lam_C k59_366039_1 746697.Aeqsu_0485 1.67e-14 80.9 COG2706@1|root,COG2706@2|Bacteria,4NN57@976|Bacteroidetes 976|Bacteroidetes G Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - VCBS k59_196179_1 1121459.AQXE01000001_gene2737 1.73e-30 114.0 2EMTV@1|root,33FG7@2|Bacteria 2|Bacteria S Gene 88 protein - - - - - - - - - - - - GP88 k59_305656_1 1688.BCUN_0824 4.71e-31 130.0 COG0553@1|root,COG0553@2|Bacteria,2IC31@201174|Actinobacteria 201174|Actinobacteria KL Superfamily II DNA RNA helicases, SNF2 family - - - - - - - - - - - - SNF2_N k59_281907_1 935866.JAER01000003_gene1168 4.6e-20 96.3 COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,4DPA7@85009|Propionibacteriales 201174|Actinobacteria E D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT k59_366100_1 1185652.USDA257_c43080 3.6e-15 76.6 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,2U1P9@28211|Alphaproteobacteria,4BDQ9@82115|Rhizobiaceae 28211|Alphaproteobacteria S DNA packaging protein gp2 - - - - - - - - - - - - Terminase_6,Terminase_6C k59_183491_1 457415.HMPREF1006_02476 8.49e-14 78.6 COG3087@1|root,COG3087@2|Bacteria,3TAF9@508458|Synergistetes 508458|Synergistetes D Caudovirus prohead serine protease - - - - - - - - - - - - Peptidase_S78 k59_99944_1 1609634.A0A0C5AFV4_9VIRU 6.11e-120 359.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_294418_2 1089551.KE386572_gene1280 1.54e-20 90.1 COG2520@1|root,COG2520@2|Bacteria,1MZTC@1224|Proteobacteria,2UE8C@28211|Alphaproteobacteria,4BSBW@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria J Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 k59_366961_3 158189.SpiBuddy_1836 1.8e-15 81.3 COG0629@1|root,COG0629@2|Bacteria 2|Bacteria L single-stranded DNA binding - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - ERF,SSB k59_366961_6 1408415.JHXL01000003_gene1141 1.08e-05 55.1 COG3598@1|root,COG3598@2|Bacteria 2|Bacteria L Psort location Cytoplasmic, score - - - ko:K07505 - - - - ko00000 - - - AAA_25,PriCT_2 k59_209806_3 1618248.A0A0C5IB82_9CIRC 1.64e-87 270.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_379448_1 1385658.U5KPZ6_9VIRU 5.39e-46 166.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_233695_2 266835.14021429 4.71e-30 119.0 COG1783@1|root,COG1783@2|Bacteria,1MVJB@1224|Proteobacteria,2U2BM@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_319071_2 1379718.S5TMX4_9CIRC 5.77e-63 206.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_221926_1 1618248.A0A0C5IB82_9CIRC 3.67e-28 112.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_209940_1 27679.XP_010331018.1 1.61e-21 96.7 COG2036@1|root,KOG4012@1|root,KOG1745@2759|Eukaryota,KOG3467@2759|Eukaryota,KOG4012@2759|Eukaryota,3A2P2@33154|Opisthokonta,3BQQV@33208|Metazoa,3CS7Q@33213|Bilateria,48562@7711|Chordata,492U7@7742|Vertebrata,3JE5M@40674|Mammalia,3590T@314146|Euarchontoglires,4M8VZ@9443|Primates 33208|Metazoa B Histone cluster 1, H1b HIST1H1B GO:0000122,GO:0000228,GO:0000785,GO:0000790,GO:0000792,GO:0001558,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005720,GO:0006325,GO:0006355,GO:0006357,GO:0006996,GO:0007275,GO:0007517,GO:0008104,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010604,GO:0010605,GO:0010629,GO:0010638,GO:0016043,GO:0019219,GO:0019222,GO:0019899,GO:0030307,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031399,GO:0031401,GO:0031490,GO:0031647,GO:0031974,GO:0031981,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0033036,GO:0033043,GO:0033044,GO:0033365,GO:0034502,GO:0034613,GO:0040008,GO:0042826,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0045184,GO:0045892,GO:0045927,GO:0045934,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0050821,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051276,GO:0051570,GO:0051574,GO:0051641,GO:0060255,GO:0061061,GO:0065007,GO:0065008,GO:0070013,GO:0070199,GO:0070727,GO:0071168,GO:0071169,GO:0071840,GO:0072594,GO:0080090,GO:0097159,GO:1901363,GO:1902275,GO:1902679,GO:1903506,GO:1903507,GO:1905269,GO:2000112,GO:2000113,GO:2001141,GO:2001252 - ko:K11252,ko:K11254,ko:K11275 ko05034,ko05203,ko05322,map05034,map05203,map05322 - - - ko00000,ko00001,ko03036,ko04147 - - - Linker_histone k59_39039_1 626887.J057_01635 1.55e-22 99.8 COG4932@1|root,COG5434@1|root,COG4932@2|Bacteria,COG5434@2|Bacteria 2|Bacteria M polygalacturonase activity - - - - - - - - - - - - Beta_helix,Big_2,F5_F8_type_C,HemolysinCabind,SdrD_B k59_88052_1 649638.Trad_1810 2.23e-17 85.9 COG4983@1|root,COG4983@2|Bacteria,1WKF7@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L DNA primase - - - - - - - - - - - - - k59_271067_1 1121468.AUBR01000006_gene314 2.06e-48 173.0 COG4626@1|root,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,248RI@186801|Clostridia,42EYP@68295|Thermoanaerobacterales 186801|Clostridia L Phage Terminase - - - - - - - - - - - - Terminase_1 k59_332391_2 428125.CLOLEP_01413 2.43e-32 116.0 2E2Y0@1|root,32XYV@2|Bacteria,1VD9S@1239|Firmicutes,24PK0@186801|Clostridia,3WPDR@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_162180_1 247490.KSU1_C0231 7.73e-25 105.0 2CDQ7@1|root,2Z7KV@2|Bacteria,2J41Q@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_15313_1 1122139.KB907868_gene1223 1.03e-10 73.6 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1XI69@135619|Oceanospirillales 135619|Oceanospirillales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_89235_1 243924.LT42_17145 3.65e-123 368.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1RP8Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria K terminase - - - - - - - - - - - - Terminase_1 k59_89236_2 521460.Athe_2026 1.41e-08 57.0 COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,42F9X@68295|Thermoanaerobacterales 186801|Clostridia L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_3,Phage_integrase k59_174348_1 1618248.A0A0C5IB82_9CIRC 9.05e-18 89.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_28414_1 1147150.K7PM60_9CAUD 4.65e-44 151.0 4QB1F@10239|Viruses,4QUYH@35237|dsDNA viruses no RNA stage,4QPSW@28883|Caudovirales,4QKPW@10699|Siphoviridae 10699|Siphoviridae S exonuclease activity - - - - - - - - - - - - - k59_28414_2 1123279.ATUS01000005_gene3102 1.33e-36 138.0 2CJWY@1|root,31CWF@2|Bacteria,1RKEF@1224|Proteobacteria,1S75P@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_127109_3 691965.D4P7B9_9CAUD 1.17e-24 97.1 4QFDH@10239|Viruses,4QWV5@35237|dsDNA viruses no RNA stage,4QPB8@28883|Caudovirales,4QKNN@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_127109_4 748727.CLJU_c03740 3.87e-14 78.6 COG3103@1|root,COG5632@1|root,COG4991@2|Bacteria,COG5632@2|Bacteria,1V7KT@1239|Firmicutes,24G8M@186801|Clostridia,36I7B@31979|Clostridiaceae 186801|Clostridia M N-acetylmuramoyl-L-alanine amidase ampD - 3.5.1.28 ko:K01447,ko:K11062 - - R04112 RC00064,RC00141 ko00000,ko01000,ko02042 - - - Amidase_2,CW_binding_1,DUF4214,Glucosaminidase,PG_binding_1,SH3_3 k59_381958_1 471881.PROPEN_02005 1.12e-21 93.2 2CWYZ@1|root,32T0P@2|Bacteria,1MZEM@1224|Proteobacteria,1S9HP@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_357547_1 445692.E3SP83_9CAUD 1.86e-85 257.0 4QD0J@10239|Viruses,4R0A5@35237|dsDNA viruses no RNA stage,4QSK9@28883|Caudovirales,4QNR4@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_102738_1 1348908.KI518589_gene2548 4.35e-07 60.8 COG3378@1|root,COG3378@2|Bacteria,1TQP9@1239|Firmicutes,4HA5U@91061|Bacilli,1ZQE6@1386|Bacillus 91061|Bacilli S Phage plasmid primase, P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5 k59_345664_1 1121127.JAFA01000044_gene6695 1.6e-06 57.4 COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,2VIEC@28216|Betaproteobacteria,1K27X@119060|Burkholderiaceae 28216|Betaproteobacteria L helicase - - 2.7.11.1 ko:K08282 - - - - ko00000,ko01000 - - - DUF3670,Helicase_C,SNF2_N,SWIM k59_5641_1 215158.FIBER_BPE15 5.5e-20 93.6 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNBD@10744|Podoviridae 10744|Podoviridae S outer membrane - GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0008150,GO:0016032,GO:0016787,GO:0016798,GO:0019012,GO:0019058,GO:0019062,GO:0022610,GO:0044403,GO:0044406,GO:0044409,GO:0044411,GO:0044419,GO:0044423,GO:0044650,GO:0051701,GO:0051704,GO:0051828,GO:0051830,GO:0085027,GO:0098015,GO:0098024 - - - - - - - - - - - k59_66380_1 1122222.AXWR01000006_gene2725 2.79e-25 110.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1WIA1@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,Taq-exonuc k59_151238_1 469596.HMPREF9488_03270 1.38e-14 72.4 COG0758@1|root,COG0758@2|Bacteria,1VNFT@1239|Firmicutes 1239|Firmicutes LU Protein of unknown function (DUF2493) - - - - - - - - - - - - DUF2493 k59_5645_1 1452718.JBOY01000021_gene717 2.75e-34 129.0 2DKZ2@1|root,32UFZ@2|Bacteria,1N5GS@1224|Proteobacteria,1SP03@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - PDDEXK_1 k59_357553_1 990285.RGCCGE502_09275 2.76e-24 99.8 COG3740@1|root,COG3740@2|Bacteria,1NHKT@1224|Proteobacteria,2U82W@28211|Alphaproteobacteria,4BDKN@82115|Rhizobiaceae 28211|Alphaproteobacteria S Caudovirus prohead serine protease - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78 k59_151240_1 742766.HMPREF9455_03102 7.36e-27 116.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,4NMBI@976|Bacteroidetes,2FR6N@200643|Bacteroidia 976|Bacteroidetes D nuclear chromosome segregation - - - - - - - - - - - - - k59_309342_1 211586.SO_2958 0.000416 45.4 2DNB5@1|root,32WIW@2|Bacteria,1N0BM@1224|Proteobacteria,1S8UT@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacteriophage HK97-gp10, putative tail-component - - - - - - - - - - - - HK97-gp10_like k59_345666_2 1618238.A0A0C5IB41_9CIRC 2.63e-08 62.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_78343_1 411460.RUMTOR_02036 1.92e-103 335.0 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_333804_1 314231.FP2506_00470 2.62e-13 73.2 COG1475@1|root,COG1475@2|Bacteria,1MVF9@1224|Proteobacteria,2TR0P@28211|Alphaproteobacteria,2PJQC@255475|Aurantimonadaceae 28211|Alphaproteobacteria K ParB domain protein nuclease - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_333804_3 1408428.JNJP01000010_gene1294 1.14e-29 125.0 COG4227@1|root,COG4643@1|root,COG4227@2|Bacteria,COG4643@2|Bacteria,1MU8I@1224|Proteobacteria,42N43@68525|delta/epsilon subdivisions,2WM7N@28221|Deltaproteobacteria,2M823@213115|Desulfovibrionales 28221|Deltaproteobacteria L Domain of unknown function (DUF1738) - - - - - - - - - - - - DUF1738,Toprim_3 k59_333804_5 1121123.AUAO01000004_gene1662 1.72e-27 106.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2U5BZ@28211|Alphaproteobacteria,2KGA6@204458|Caulobacterales 204458|Caulobacterales L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_333804_7 69279.BG36_21015 2.76e-52 176.0 COG3206@1|root,COG3206@2|Bacteria,1ND5H@1224|Proteobacteria,2UIQZ@28211|Alphaproteobacteria,43P6G@69277|Phyllobacteriaceae 28211|Alphaproteobacteria M protein involved in exopolysaccharide biosynthesis - - - - - - - - - - - - - k59_333804_9 1121105.ATXL01000006_gene1360 5.58e-09 63.9 COG5377@1|root,COG5377@2|Bacteria,1TS2Y@1239|Firmicutes,4HAFK@91061|Bacilli,4B20D@81852|Enterococcaceae 91061|Bacilli L YqaJ-like viral recombinase domain yqaJ - - - - - - - - - - - YqaJ k59_333804_11 1094560.ME9_00989 1.79e-07 57.0 COG3756@1|root,COG3756@2|Bacteria,1P6UX@1224|Proteobacteria,2UC8G@28211|Alphaproteobacteria,48UNA@772|Bartonellaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1376) - - - - - - - - - - - - DUF1376 k59_30214_1 1121459.AQXE01000001_gene2765 2.13e-61 208.0 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,42YUP@68525|delta/epsilon subdivisions,2WTS1@28221|Deltaproteobacteria,2MAPB@213115|Desulfovibrionales 28221|Deltaproteobacteria L DNA polymerase A domain - - - - - - - - - - - - DNA_pol_A k59_297388_2 322855.Q52PN4_9CAUD 4.11e-45 173.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales 28883|Caudovirales S N-methyltransferase activity - - - - - - - - - - - - - k59_214120_1 105154.Q9MBU6_9VIRU 8.03e-57 200.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_310684_1 1432056.X781_8090 3.86e-41 149.0 COG4653@1|root,COG4653@2|Bacteria,1MYMH@1224|Proteobacteria,1RR5E@1236|Gammaproteobacteria,1Y809@135625|Pasteurellales 135625|Pasteurellales S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_358837_1 622637.KE124774_gene3857 6.92e-25 104.0 COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,2TT4K@28211|Alphaproteobacteria,36YBH@31993|Methylocystaceae 28211|Alphaproteobacteria M Polysaccharide biosynthesis protein capD - 5.1.3.2 ko:K17716 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00362 R00291 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Polysacc_syn_2C,Polysacc_synt_2 k59_358837_3 1122947.FR7_2451 4.69e-66 212.0 COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,4H3QB@909932|Negativicutes 909932|Negativicutes M UDP-N-acetylglucosamine 2-epimerase - - 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase_2 k59_310685_1 1385658.U5KNR1_9VIRU 5.13e-30 119.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_383066_1 172088.AUGA01000106_gene3334 2.46e-06 52.8 2D2PS@1|root,32TD8@2|Bacteria,1N5HS@1224|Proteobacteria,2UDMM@28211|Alphaproteobacteria,3JZ1B@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_115944_2 283699.D172_4039 7.76e-24 96.3 COG3772@1|root,COG3772@2|Bacteria,1N0ZQ@1224|Proteobacteria,1S9AE@1236|Gammaproteobacteria,2Q38I@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_17941_1 1379708.S5SYC3_9CIRC 3.49e-27 110.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_67995_1 105154.Q9MBU6_9VIRU 8.41e-99 308.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_128784_1 248742.XP_005647828.1 4.47e-48 168.0 COG0180@1|root,KOG2713@2759|Eukaryota,37SNS@33090|Viridiplantae,34GYE@3041|Chlorophyta 3041|Chlorophyta J Belongs to the class-I aminoacyl-tRNA synthetase family - - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b k59_323339_1 330214.NIDE0885 5.21e-35 134.0 COG0399@1|root,COG0399@2|Bacteria,3J09X@40117|Nitrospirae 2|Bacteria E Belongs to the DegT DnrJ EryC1 family spsC - 2.6.1.102 ko:K13010 ko00520,map00520 - R10460 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 - - - DegT_DnrJ_EryC1 k59_288218_1 411476.BACOVA_03891 3.16e-09 58.5 COG3935@1|root,COG3935@2|Bacteria,4PMTW@976|Bacteroidetes,2FTAY@200643|Bacteroidia,4ARAF@815|Bacteroidaceae 976|Bacteroidetes L DnaD domain protein - - - - - - - - - - - - - k59_274234_1 240015.ACP_1361 3.21e-56 188.0 COG0451@1|root,COG0451@2|Bacteria 2|Bacteria GM ADP-glyceromanno-heptose 6-epimerase activity sqdB - 3.13.1.1 ko:K06118 ko00520,ko00561,map00520,map00561 - R05775 RC01469 ko00000,ko00001,ko01000 - - iJN678.sqdB Epimerase k59_383071_2 1609634.A0A0C5ANA6_9VIRU 8.68e-10 64.7 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_186797_1 58123.JOFJ01000005_gene1530 4.84e-13 75.5 COG4886@1|root,COG4886@2|Bacteria,2GNZ0@201174|Actinobacteria,4EI25@85012|Streptosporangiales 201174|Actinobacteria S Leucine-rich repeat (LRR) protein - - - - - - - - - - - - - k59_249957_1 1385658.U5KPZ6_9VIRU 2.82e-87 275.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_249957_2 105154.Q9MBU3_9VIRU 8.59e-10 63.5 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_7093_1 1415166.NONO_c60570 1.36e-61 204.0 COG4641@1|root,COG4641@2|Bacteria,2H1Z7@201174|Actinobacteria 201174|Actinobacteria S Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_2 k59_177458_1 438753.AZC_3583 1.51e-49 178.0 28IA2@1|root,2Z8CQ@2|Bacteria,1PQM2@1224|Proteobacteria,2TUAP@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_325115_1 632518.Calow_0840 1.95e-11 69.7 COG3941@1|root,COG3941@2|Bacteria,1V33U@1239|Firmicutes 1239|Firmicutes M tape measure - - - - - - - - - - - - SLT k59_69679_1 1234888.K0A2J2_9VIRU 4.45e-47 167.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_105696_1 2903.EOD09222 3.2e-05 50.4 COG0318@1|root,KOG1176@2759|Eukaryota 2759|Eukaryota IQ ligase activity - - - - - - - - - - - - AMP-binding,AMP-binding_C,Condensation,FSH1,PP-binding k59_203089_1 1234888.K0A2J2_9VIRU 1.54e-56 192.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_179355_2 1089551.KE386572_gene951 3.14e-48 162.0 COG4725@1|root,COG4725@2|Bacteria,1R553@1224|Proteobacteria,2TRP6@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT Belongs to the MT-A70-like family - - - - - - - - - - - - MT-A70 k59_19516_4 926561.KB900622_gene630 3.93e-14 72.0 COG3108@1|root,COG3108@2|Bacteria,1VFRJ@1239|Firmicutes,24R9N@186801|Clostridia 186801|Clostridia M Peptidase M15A - - 3.4.17.14 ko:K08640 - - - - ko00000,ko01000,ko01002,ko01011 - - - PG_binding_1,Peptidase_M15_3 k59_94556_1 1232437.KL662011_gene1483 3.76e-32 138.0 COG3292@1|root,COG5306@1|root,COG3292@2|Bacteria,COG5306@2|Bacteria 2|Bacteria - - exbB2 - - ko:K03561,ko:K12287 - - - - ko00000,ko02000,ko02044 1.A.30.2.1 - - DUF2341,DUF5074,Laminin_G_3,MotA_ExbB,PKD_3,Reg_prop k59_263564_4 288000.BBta_5776 1.29e-16 76.3 2CC8P@1|root,2ZI81@2|Bacteria,1N10A@1224|Proteobacteria,2UD9A@28211|Alphaproteobacteria,3K0MK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_263564_5 1094557.ME3_00393 4.75e-54 196.0 2CC8M@1|root,308VJ@2|Bacteria,1R789@1224|Proteobacteria,2U2NB@28211|Alphaproteobacteria,48T5T@772|Bartonellaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_19689_3 572265.HDEF_1701 4.67e-34 123.0 2AD08@1|root,312N7@2|Bacteria,1NDC4@1224|Proteobacteria,1SAPT@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_240994_1 873448.STRPO_0046 1.86e-25 108.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H9YP@91061|Bacilli 91061|Bacilli L SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_35184_1 509191.AEDB02000020_gene3287 7.8e-11 68.2 2CC4J@1|root,2Z7W8@2|Bacteria,1UX5W@1239|Firmicutes,24DCZ@186801|Clostridia,3WGCS@541000|Ruminococcaceae 186801|Clostridia S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_204829_2 1196322.A370_04497 2.23e-22 104.0 COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia,36JX7@31979|Clostridiaceae 186801|Clostridia O PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - 3.4.21.66 ko:K08651,ko:K13274,ko:K14645,ko:K20486 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - Big_2,Peptidase_S8,SLH k59_327026_1 1385658.U5KPZ6_9VIRU 1.26e-71 235.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_47069_1 555793.WSK_4248 3.61e-11 67.0 COG0859@1|root,COG0859@2|Bacteria,1QUID@1224|Proteobacteria,2TW45@28211|Alphaproteobacteria,2K153@204457|Sphingomonadales 204457|Sphingomonadales M COG0457 FOG TPR repeat - - - - - - - - - - - - Glyco_transf_9 k59_47069_2 589924.Ferp_2404 1.11e-06 55.5 arCOG03850@1|root,arCOG03850@2157|Archaea,2XYUB@28890|Euryarchaeota 28890|Euryarchaeota S Cephalosporin hydroxylase - - - - - - - - - - - - Methyltransf_24 k59_96749_1 439497.RR11_2712 1.74e-34 126.0 COG0692@1|root,COG0692@2|Bacteria,1MV80@1224|Proteobacteria,2U1VI@28211|Alphaproteobacteria,4NBHV@97050|Ruegeria 28211|Alphaproteobacteria L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung - 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_277730_2 1515613.HQ37_02150 3.4e-32 125.0 COG1212@1|root,COG1212@2|Bacteria,4NG4B@976|Bacteroidetes,2FMHD@200643|Bacteroidia,22XG8@171551|Porphyromonadaceae 976|Bacteroidetes M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB - 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 k59_10244_1 1692242.A0A0K1RKZ2_9CIRC 1.38e-12 71.2 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_362207_1 443598.AUFA01000017_gene7339 1.08e-33 125.0 COG2813@1|root,COG2813@2|Bacteria,1QYWA@1224|Proteobacteria,2TY0H@28211|Alphaproteobacteria,3K6VG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Specifically methylates the guanine in position - - - - - - - - - - - - - k59_119409_2 1537917.JU82_09980 1.59e-21 90.1 2ARVA@1|root,31H70@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - HK97-gp10_like k59_230091_2 1071177.G3EN97_9CAUD 1.74e-26 115.0 4QAYV@10239|Viruses,4QUZ7@35237|dsDNA viruses no RNA stage,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - k59_327180_1 1204534.J9QD24_9CAUD 2.39e-14 68.9 4QBV5@10239|Viruses,4QVEI@35237|dsDNA viruses no RNA stage,4QPNX@28883|Caudovirales,4QKH1@10662|Myoviridae 10662|Myoviridae S Domain of Unknown Function with PDB structure (DUF3850) - - - - - - - - - - - - - k59_352364_1 742740.HMPREF9474_02299 6.29e-104 316.0 COG0553@1|root,COG0553@2|Bacteria,1TS9W@1239|Firmicutes,24CGX@186801|Clostridia,222GT@1506553|Lachnoclostridium 186801|Clostridia KL Helicase conserved C-terminal domain - - - - - - - - - - - - - k59_22998_1 1618242.A0A0C5IB65_9CIRC 6.42e-08 54.7 4QAUG@10239|Viruses,4QUM5@29258|ssDNA viruses 10239|Viruses L Parvovirus non-structural protein NS1 - GO:0001906,GO:0001907,GO:0005575,GO:0008150,GO:0009889,GO:0010556,GO:0010941,GO:0010942,GO:0016032,GO:0018995,GO:0019048,GO:0019051,GO:0019054,GO:0019056,GO:0019058,GO:0019079,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031341,GO:0031343,GO:0031640,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0035821,GO:0039526,GO:0039592,GO:0039656,GO:0039685,GO:0039693,GO:0042025,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043656,GO:0043657,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044071,GO:0044215,GO:0044216,GO:0044217,GO:0044364,GO:0044403,GO:0044419,GO:0044531,GO:0044532,GO:0044533,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051709,GO:0051712,GO:0051726,GO:0051817,GO:0051818,GO:0051883,GO:0052026,GO:0052040,GO:0052042,GO:0052150,GO:0052151,GO:0052248,GO:0052312,GO:0052330,GO:0052433,GO:0052501,GO:0060139,GO:0060153,GO:0060255,GO:0065007,GO:0080090,GO:2001141 - - - - - - - - - - - k59_22998_2 1692256.A0A0K1RL85_9CIRC 2.64e-15 82.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_376409_2 1167006.UWK_01394 8.35e-74 254.0 COG2204@1|root,COG2461@1|root,COG3275@1|root,COG4191@1|root,COG2204@2|Bacteria,COG2461@2|Bacteria,COG3275@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MJ29@213118|Desulfobacterales 28221|Deltaproteobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3,dCache_3 k59_376411_1 1096930.L284_16985 6.52e-36 143.0 COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria,2U1JR@28211|Alphaproteobacteria,2K8IS@204457|Sphingomonadales 204457|Sphingomonadales K DNA-directed RNA polymerase N-terminal - - - - - - - - - - - - RNA_pol,RPOL_N k59_266826_1 1234888.K0A2J2_9VIRU 8.16e-128 384.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_266826_4 145579.REP_BPPHM 8.81e-10 66.2 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_190981_1 1385658.U5KPZ6_9VIRU 6.01e-44 158.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_121423_1 1618236.A0A0C5IB23_9CIRC 3.38e-31 127.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388309_3 1385658.U5KPZ6_9VIRU 2.6e-172 504.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_316188_1 990285.RGCCGE502_22660 7.45e-28 110.0 COG3179@1|root,COG3179@2|Bacteria,1RFSU@1224|Proteobacteria,2UDYJ@28211|Alphaproteobacteria,4BCH1@82115|Rhizobiaceae 28211|Alphaproteobacteria S chitinase - - - ko:K03791 - - - - ko00000 - GH19 - Glyco_hydro_19 k59_158269_1 1267535.KB906767_gene157 3.38e-74 236.0 COG1215@1|root,COG1215@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_tranf_2_4 k59_158269_2 1045856.EcWSU1_01383 4.39e-20 92.4 COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,1RNWN@1236|Gammaproteobacteria,3X12T@547|Enterobacter 1236|Gammaproteobacteria H Catalyzes the reversible formation of fructose 6- phosphate from dihydroxyacetone and D-glyceraldehyde 3-phosphate via an aldolization reaction fsaA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016832,GO:0044424,GO:0044464,GO:0097023 - ko:K08313,ko:K08314 - - - - ko00000,ko01000 - - iEC042_1314.EC042_0914,iSBO_1134.SBO_0715,iSF_1195.SF0775,iSFxv_1172.SFxv_0845,iS_1188.S0818 TAL_FSA k59_158269_4 398525.KB900701_gene2875 9.26e-62 204.0 COG0451@1|root,COG0451@2|Bacteria,1MUGT@1224|Proteobacteria,2TRF6@28211|Alphaproteobacteria,3JTUM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction fcl - 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R05692 RC01014 ko00000,ko00001,ko01000 - - - Epimerase k59_97418_1 1234888.K0A2J2_9VIRU 3.88e-43 157.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_231034_4 694427.Palpr_1970 2.18e-15 82.8 COG4675@1|root,COG4675@2|Bacteria 2|Bacteria M tail collar domain protein - - - - - - - - - - - - Collar k59_376946_3 1234888.K0A2R8_9VIRU 8e-10 60.1 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_376949_1 1280679.ATVX01000011_gene2437 1.26e-06 53.5 COG4641@1|root,COG4641@2|Bacteria,1TS28@1239|Firmicutes,24E2J@186801|Clostridia,4BYV0@830|Butyrivibrio 186801|Clostridia S DUF based on E. rectale Gene description (DUF3880) - - - ko:K06320 - - - - ko00000 - - - DUF3880,Glyco_trans_1_2 k59_24518_1 742740.HMPREF9474_02314 8.02e-68 217.0 2A0KC@1|root,30NQJ@2|Bacteria,1V3K4@1239|Firmicutes,24HYK@186801|Clostridia,222N6@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_146100_2 1110502.TMO_1599 3.59e-61 196.0 28NA5@1|root,2ZBDZ@2|Bacteria,1MXY5@1224|Proteobacteria,2TYZX@28211|Alphaproteobacteria,2JWJ4@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_279856_1 882.DVU_1515 2.73e-12 72.0 COG0270@1|root,COG0270@2|Bacteria,1PPPB@1224|Proteobacteria,43A4E@68525|delta/epsilon subdivisions,2WUDB@28221|Deltaproteobacteria,2MB1N@213115|Desulfovibrionales 28221|Deltaproteobacteria L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_376994_3 1035191.HMPREF0185_01995 7.59e-36 136.0 COG4227@1|root,COG4227@2|Bacteria,1MU8I@1224|Proteobacteria,2TRIT@28211|Alphaproteobacteria,2KGTX@204458|Caulobacterales 204458|Caulobacterales L Domain of unknown function (DUF1738) - - - - - - - - - - - - DUF1738 k59_36745_8 234267.Acid_0568 1.63e-56 205.0 COG2192@1|root,COG2192@2|Bacteria,3Y37V@57723|Acidobacteria 57723|Acidobacteria O Carbamoyltransferase C-terminus - - - ko:K00612 - - - - ko00000,ko01000 - - - Carbam_trans_C,Carbam_trans_N k59_36745_9 72019.SARC_05221T0 1.26e-08 65.1 28KVY@1|root,2RXKG@2759|Eukaryota 2759|Eukaryota S Bacterial protein of unknown function (HtrL_YibB) - - - - - - - - - - - - HtrL_YibB k59_158289_16 1029824.AFID01000003_gene199 2.45e-16 80.9 COG0566@1|root,COG0566@2|Bacteria,2GM1A@201174|Actinobacteria,1W7E6@1268|Micrococcaceae 201174|Actinobacteria J rRNA methyltransferase trmH - 2.1.1.34 ko:K00556 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase k59_158289_17 1289387.AUKW01000005_gene1653 3.51e-13 66.6 2CC86@1|root,3043Z@2|Bacteria,2IRMY@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_48976_3 105154.Q9MBU6_9VIRU 1.15e-77 253.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_291872_1 1443111.JASG01000004_gene1249 1.53e-05 52.4 COG2931@1|root,COG4932@1|root,COG5295@1|root,COG2931@2|Bacteria,COG4932@2|Bacteria,COG5295@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,3ZUZ8@60136|Sulfitobacter 28211|Alphaproteobacteria Q Hint domain - - - - - - - - - - - - HemolysinCabind,Hint_2 k59_134096_1 1304878.AUGD01000009_gene6394 5.25e-14 73.9 2BHJH@1|root,32BMY@2|Bacteria,1N52Q@1224|Proteobacteria,2UDD3@28211|Alphaproteobacteria,3K0TQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_340634_1 742738.HMPREF9460_02740 4.37e-17 87.4 COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia,267RH@186813|unclassified Clostridiales 186801|Clostridia D Peptidase family M23 - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 k59_37006_1 1379717.S5SY19_9CIRC 5.62e-18 85.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_243461_1 511.JT27_18325 4.94e-127 403.0 COG0749@1|root,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2VJ57@28216|Betaproteobacteria,3T32Z@506|Alcaligenaceae 1224|Proteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - - - - - - - - - - - DNA_pol_A k59_97767_2 497964.CfE428DRAFT_1361 1.98e-21 100.0 COG5283@1|root,COG5283@2|Bacteria,46VP2@74201|Verrucomicrobia 74201|Verrucomicrobia - - - - - - - - - - - - - - - k59_340713_2 1385658.U5KPZ6_9VIRU 1.11e-142 422.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_195152_1 279010.BL03493 5.28e-28 117.0 COG3378@1|root,COG4983@1|root,COG3378@2|Bacteria,COG4983@2|Bacteria,1TQP9@1239|Firmicutes,4HBTB@91061|Bacilli,1ZEU3@1386|Bacillus 91061|Bacilli S D5 N terminal like - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,PriCT_1,Prim-Pol k59_377352_1 765698.Mesci_4964 3.49e-29 111.0 COG0500@1|root,COG0500@2|Bacteria,1R4KQ@1224|Proteobacteria,2U35H@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q methyltransferase - - - - - - - - - - - - - k59_109963_5 1268072.PSAB_06080 1.84e-35 137.0 2ENRS@1|root,32H5X@2|Bacteria,1U0J9@1239|Firmicutes,4I9Y7@91061|Bacilli,2724K@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - k59_170581_1 1038860.AXAP01000015_gene1988 8.26e-47 174.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria,3JTQV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_255689_1 1278073.MYSTI_01971 4.23e-46 162.0 COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,42UB3@68525|delta/epsilon subdivisions 1224|Proteobacteria H COG0270 Site-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_24905_1 1111454.HMPREF1250_1038 8.55e-16 74.7 2EI4V@1|root,33BW7@2|Bacteria,1VKQH@1239|Firmicutes 1239|Firmicutes S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_24905_2 1410620.SHLA_4c002050 1.86e-12 66.6 COG1694@1|root,COG1694@2|Bacteria,1N3XF@1224|Proteobacteria,2UG4F@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Mazg nucleotide pyrophosphohydrolase - - - - - - - - - - - - - k59_122172_1 262724.TT_C1062 1.15e-37 154.0 COG0210@1|root,COG0210@2|Bacteria,1WI0I@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L PFAM UvrD REP helicase uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - DUF3553,UvrD-helicase,UvrD_C k59_97782_1 1692244.A0A0K1RLR5_9CIRC 2.3e-26 109.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_37036_4 797114.C475_13272 6e-05 55.5 arCOG07813@1|root,arCOG07813@2157|Archaea,2Y1X7@28890|Euryarchaeota 28890|Euryarchaeota G Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - Laminin_G_3 k59_122173_1 693746.OBV_41780 2.29e-12 73.6 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia 186801|Clostridia L DNA polymerase - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_365022_2 742733.HMPREF9469_05020 2.64e-151 518.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,221IX@1506553|Lachnoclostridium 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_365022_3 742740.HMPREF9474_02263 2.47e-27 104.0 2ARVA@1|root,31H70@2|Bacteria,1V7JT@1239|Firmicutes,24JPE@186801|Clostridia,222RD@1506553|Lachnoclostridium 186801|Clostridia S Bacteriophage HK97-gp10, putative tail-component - - - - - - - - - - - - HK97-gp10_like k59_292279_2 450851.PHZ_c2212 2.62e-45 159.0 COG5323@1|root,COG5323@2|Bacteria,1R0EP@1224|Proteobacteria,2TYQ7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - - k59_73582_4 323259.Mhun_0597 2.91e-07 63.2 COG3291@1|root,arCOG02559@1|root,arCOG06792@1|root,arCOG02508@2157|Archaea,arCOG02559@2157|Archaea,arCOG06792@2157|Archaea,2XUY6@28890|Euryarchaeota,2NAFS@224756|Methanomicrobia 224756|Methanomicrobia O PFAM PKD domain containing protein - - - - - - - - - - - - PKD k59_220480_1 1986029.Q9MBM8_9VIRU 4.18e-121 368.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_220480_4 1385658.U5KNR1_9VIRU 5.76e-65 214.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_220480_6 145579.CAPSD_BPPHM 7.98e-41 149.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_268794_1 1246626.BleG1_2873 7.3e-06 56.2 COG1196@1|root,COG4942@1|root,COG5283@1|root,COG1196@2|Bacteria,COG4942@2|Bacteria,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,4HGW7@91061|Bacilli,1ZBWW@1386|Bacillus 91061|Bacilli D phage tail tape measure protein - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,SLT k59_220485_2 1618251.A0A0C5I2L8_9CIRC 1.94e-22 102.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_110875_1 1385658.U5KNR1_9VIRU 1.82e-44 159.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_135014_2 1120963.KB894514_gene385 8.48e-21 86.7 2CPEB@1|root,32SIW@2|Bacteria,1MZE0@1224|Proteobacteria,1SARU@1236|Gammaproteobacteria,2Q4T5@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_305397_1 216142.LT40_12420 1.86e-43 154.0 COG2404@1|root,COG2404@2|Bacteria,1MXEH@1224|Proteobacteria,1SADM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S phosphoesterase DHHA1 - - - - - - - - - - - - DHHA1 k59_305397_3 686340.Metal_1761 1.37e-06 50.8 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria,1XE00@135618|Methylococcales 135618|Methylococcales K sigma54 specific, transcriptional regulator, Fis family - - - ko:K10941 ko02020,ko02025,ko05111,map02020,map02025,map05111 - - - ko00000,ko00001,ko03000 - - - FleQ,HTH_8,Sigma54_activat k59_25823_1 10855.H_SPV4 1.02e-08 58.5 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_86469_5 1197951.I6RT34_9CAUD 3.25e-102 311.0 4QGAG@10239|Viruses,4R0KB@35237|dsDNA viruses no RNA stage,4QUA4@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_317607_5 401053.AciPR4_3094 3.7e-11 62.8 COG0270@1|root,COG0270@2|Bacteria,3Y5V5@57723|Acidobacteria,2JNSG@204432|Acidobacteriia 204432|Acidobacteriia L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_256759_1 237368.SCABRO_02820 0.000151 53.1 COG3209@1|root,COG3209@2|Bacteria 2|Bacteria M self proteolysis - - - - - - - - - - - - CHU_C,Peptidase_S74,SprB,TPR_8 k59_208398_1 1463900.JOIX01000006_gene741 4.96e-15 80.5 COG1783@1|root,COG1783@2|Bacteria,2I8SC@201174|Actinobacteria 201174|Actinobacteria S Terminase-like family - - - - - - - - - - - - Terminase_3,Terminase_6,Terminase_6C k59_354183_1 1385658.U5KPZ6_9VIRU 3.7e-164 479.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_196010_2 161156.JQKW01000006_gene1092 1.08e-10 70.9 COG1475@1|root,COG1475@2|Bacteria,2GGT2@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria K Belongs to the ParB family - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_171709_1 1041142.ATTP01000043_gene5288 1.85e-28 124.0 28QU5@1|root,2ZD9H@2|Bacteria,1RAU8@1224|Proteobacteria,2U2GD@28211|Alphaproteobacteria,4BC6R@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_355031_1 105154.Q9MBU6_9VIRU 6.62e-68 226.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_26934_3 1540095.A0A0A0YP73_9CAUD 2.87e-14 74.7 4QAVB@10239|Viruses,4QPIJ@28883|Caudovirales,4QI48@10662|Myoviridae 10662|Myoviridae S defense response to bacterium - - - - - - - - - - - - - k59_294255_3 234621.RER_13350 1.98e-09 67.0 COG4886@1|root,COG4886@2|Bacteria,2GNZ0@201174|Actinobacteria,4FZF9@85025|Nocardiaceae 201174|Actinobacteria S Leucine-rich repeat (LRR) protein - - - - - - - - - - - - - k59_75495_2 1692250.A0A0K1RLR1_9CIRC 1.35e-51 171.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_99770_2 1692259.A0A0K1RL59_9CIRC 2.97e-17 84.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_355038_1 1445714.W0LJK3_9CAUD 2.18e-85 271.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_148223_3 1385658.U5KPZ6_9VIRU 4.72e-200 575.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_294262_2 1158614.I592_02295 0.000194 48.5 COG1196@1|root,COG1196@2|Bacteria,1TSKM@1239|Firmicutes,4I7Z5@91061|Bacilli,4B103@81852|Enterococcaceae 91061|Bacilli D AAA domain - - - - - - - - - - - - AAA_23 k59_183980_1 105154.Q9MBU6_9VIRU 1.67e-68 228.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_183980_3 1165094.RINTHH_3920 1.24e-56 190.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_331209_2 1041826.FCOL_05440 1.28e-64 205.0 COG0270@1|root,COG0270@2|Bacteria,4P351@976|Bacteroidetes,1I9UJ@117743|Flavobacteriia,2NZ0G@237|Flavobacterium 976|Bacteroidetes L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_209789_4 2003327.REP_BPCHP 1.28e-21 101.0 4QCVK@10239|Viruses,4QUMV@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_258860_1 1215092.PA6_009_00310 3.59e-17 88.6 28TC4@1|root,2ZFKJ@2|Bacteria,1P81C@1224|Proteobacteria,1SUYI@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_380489_1 1211814.CAPG01000097_gene4378 3.55e-06 55.8 COG5412@1|root,COG5412@2|Bacteria,1U9S8@1239|Firmicutes,4IJYV@91061|Bacilli,1ZEP9@1386|Bacillus 91061|Bacilli S phage tail tape measure protein - - - - - - - - - - - - - k59_222972_1 1618237.A0A0C5IMG6_9CIRC 1.54e-103 310.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_210919_1 145579.REP_BPPHM 1.86e-18 90.5 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_344007_1 1385658.U5KPZ6_9VIRU 4.6e-93 292.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_295569_3 1055815.AYYA01000027_gene574 5.61e-142 410.0 COG5527@1|root,COG5527@2|Bacteria,1RD9C@1224|Proteobacteria,1T07W@1236|Gammaproteobacteria,3NTFJ@468|Moraxellaceae 1236|Gammaproteobacteria L Initiator Replication protein - - - - - - - - - - - - Rep_3 k59_4156_1 290633.GOX0604 8.66e-10 61.6 COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2TRPB@28211|Alphaproteobacteria,2JPWI@204441|Rhodospirillales 204441|Rhodospirillales H DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3,DUF3646 k59_149642_1 357808.RoseRS_4066 1.45e-09 60.1 COG2189@1|root,COG2189@2|Bacteria 2|Bacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72,3.1.21.3 ko:K00571,ko:K01154,ko:K03933,ko:K07316 - - - - ko00000,ko01000,ko02048 - AA10,CBM73 - MethyltransfD12,N6_N4_Mtase,PT k59_149642_5 1469245.JFBG01000001_gene513 4.45e-13 69.3 COG5499@1|root,COG5499@2|Bacteria,1MZHS@1224|Proteobacteria 1224|Proteobacteria K transcription regulator containing HTH domain - - - ko:K18831 - - - - ko00000,ko02048,ko03000 - - - HTH_3,Peptidase_M78 k59_89031_1 742740.HMPREF9474_02303 1.48e-78 263.0 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia,221YV@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_356230_2 462590.A9J4Z1_BPPYU 6.42e-22 95.9 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_39983_1 1120983.KB894570_gene1264 1.29e-17 80.1 COG1432@1|root,COG1432@2|Bacteria,1MUAE@1224|Proteobacteria,2TU5M@28211|Alphaproteobacteria,1JNJY@119043|Rhodobiaceae 28211|Alphaproteobacteria S NYN domain MA20_36560 - - - - - - - - - - - NYN k59_210926_1 411901.BACCAC_01192 1.7e-45 157.0 COG0863@1|root,COG0863@2|Bacteria,4NQQ1@976|Bacteroidetes,2G1PS@200643|Bacteroidia,4ARBB@815|Bacteroidaceae 976|Bacteroidetes L DNA methylase - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_368086_2 1192868.CAIU01000008_gene927 1.62e-13 72.0 COG1783@1|root,COG1783@2|Bacteria,1PE12@1224|Proteobacteria,2V9EC@28211|Alphaproteobacteria,43QJZ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Mu-like prophage FluMu protein gp28 - - - - - - - - - - - - - k59_76735_1 1127514.H9C0U8_9CAUD 2.13e-85 272.0 4QFNJ@10239|Viruses,4R06Z@35237|dsDNA viruses no RNA stage,4QQTJ@28883|Caudovirales,4QJW3@10662|Myoviridae 10662|Myoviridae S Pfam:Terminase_6C - - - - - - - - - - - - - k59_113089_1 1379695.S5TNA9_9CIRC 1.31e-12 75.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_4310_2 1541065.JRFE01000034_gene6108 2.38e-31 121.0 2CC4J@1|root,2Z7W8@2|Bacteria,1G4C9@1117|Cyanobacteria 1117|Cyanobacteria S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_223105_2 1403819.BATR01000062_gene1906 0.000409 42.7 2B4Q9@1|root,31XGJ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_66267_1 1304883.KI912532_gene1203 3.45e-12 70.9 COG2369@1|root,COG2369@2|Bacteria,1RFUM@1224|Proteobacteria,2VTZM@28216|Betaproteobacteria 28216|Betaproteobacteria S Phage head morphogenesis protein, SPP1 gp7 family - - - - - - - - - - - - Phage_Mu_F k59_163375_1 1121946.AUAX01000015_gene6048 1.18e-05 52.8 COG2755@1|root,COG5434@1|root,COG2755@2|Bacteria,COG5434@2|Bacteria,2II7D@201174|Actinobacteria,4D8ZD@85008|Micromonosporales 201174|Actinobacteria M Glycosyl hydrolases family 28 - - - - - - - - - - - - Alpha_L_fucos,CBM_35,F5_F8_type_C,Glyco_hydro_28,Pectate_lyase_3 k59_248098_2 766499.C357_06926 1.37e-75 233.0 COG1192@1|root,COG1192@2|Bacteria,1MWRE@1224|Proteobacteria,2TSJZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria D Cobyrinic acid a,c-diamide synthase parA1 - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k59_212386_2 186617.M9M8L2_9VIRU 1.57e-37 140.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_66272_1 1448857.JFAP01000004_gene648 3.07e-10 61.2 COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,42NC6@68525|delta/epsilon subdivisions,2YMJV@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon k59_333495_1 1986029.Q9MBM8_9VIRU 7.66e-21 91.3 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_345486_2 1234888.K0A2R8_9VIRU 1.14e-20 97.4 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_321639_3 186617.M9M8L2_9VIRU 6.71e-54 187.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_199753_3 877415.JNJQ01000005_gene1382 9.55e-08 52.4 COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,3VPAB@526524|Erysipelotrichia 526524|Erysipelotrichia D CobQ CobB MinD ParA nucleotide binding domain protein - - - - - - - - - - - - AAA_31 k59_357511_1 279714.FuraDRAFT_0228 7.56e-08 58.9 COG0438@1|root,COG0438@2|Bacteria,1PEZ0@1224|Proteobacteria,2W92V@28216|Betaproteobacteria,2KT86@206351|Neisseriales 206351|Neisseriales M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k59_127096_2 903814.ELI_3221 1.42e-14 78.2 COG5519@1|root,COG5519@2|Bacteria,1TRMV@1239|Firmicutes,24BJ9@186801|Clostridia 186801|Clostridia L Psort location Cytoplasmic, score - - - - - - - - - - - - DUF927 k59_16537_1 1443113.LC20_03898 5.57e-17 84.7 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1RP8Z@1236|Gammaproteobacteria,41GWS@629|Yersinia 1236|Gammaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_381933_2 366394.Smed_1911 9.9e-61 197.0 COG2813@1|root,COG2813@2|Bacteria,1QYWA@1224|Proteobacteria,2TY0H@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Specifically methylates the guanine in position - - - - - - - - - - - - - k59_381933_7 1114964.L485_07205 2.74e-103 316.0 COG0175@1|root,COG0175@2|Bacteria 2|Bacteria EH sulfate reduction - - - - - - - - - - - - PAPS_reduct k59_163488_1 2003327.CAPSD_BPCHP 3.45e-84 268.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_334652_2 1165094.RINTHH_3920 1.25e-58 196.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_176978_1 626418.bglu_1g20910 6.76e-13 71.2 28KIJ@1|root,2ZA3S@2|Bacteria,1R4PD@1224|Proteobacteria,2VP07@28216|Betaproteobacteria,1KBS4@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_42920_1 1123508.JH636439_gene1604 1.37e-14 77.8 29XN2@1|root,30JDF@2|Bacteria,2J498@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_128369_1 1385658.U5KQQ9_9VIRU 1.04e-07 57.8 4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_346859_2 420324.KI911948_gene9072 3.24e-08 56.2 COG1403@1|root,COG1403@2|Bacteria,1NGV5@1224|Proteobacteria,2UMQJ@28211|Alphaproteobacteria,1JWF5@119045|Methylobacteriaceae 28211|Alphaproteobacteria V HNH nucleases - - - - - - - - - - - - HNH k59_382926_2 105154.Q9MBU6_9VIRU 1.59e-77 249.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_103825_1 105154.Q9MBU6_9VIRU 4.92e-113 342.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_152585_1 272942.RCAP_rcc00961 1.12e-17 89.4 COG4672@1|root,COG4672@2|Bacteria 2|Bacteria S Phage minor tail protein L - - - - - - - - - - - - - k59_213859_1 1280944.HY17_04705 2.06e-09 66.2 2E8SI@1|root,3333B@2|Bacteria,1N7MG@1224|Proteobacteria,2UJSF@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_129873_1 1385658.U5KPZ6_9VIRU 5.28e-67 222.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_384151_1 525246.HMPREF0058_0733 1.36e-16 85.1 COG0749@1|root,COG0749@2|Bacteria,2IG0A@201174|Actinobacteria,4D4MC@85005|Actinomycetales 201174|Actinobacteria L DNA polymerase - - - - - - - - - - - - DNA_pol_A k59_384151_2 1460634.JCM19037_3684 6.39e-17 87.4 COG0270@1|root,COG0270@2|Bacteria,1TPNE@1239|Firmicutes,4HHQR@91061|Bacilli 91061|Bacilli H C-5 cytosine-specific DNA methylase - - - - - - - - - - - - DNA_methylase k59_178632_1 1788452.A0A190WHG0_9CIRC 2.86e-39 146.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_32706_1 56780.SYN_00585 4.91e-50 171.0 COG0451@1|root,COG0451@2|Bacteria,1MUGT@1224|Proteobacteria,42M12@68525|delta/epsilon subdivisions,2WIJX@28221|Deltaproteobacteria,2MQ3S@213462|Syntrophobacterales 28221|Deltaproteobacteria GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction fcl - 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R05692 RC01014 ko00000,ko00001,ko01000 - - iAF987.Gmet_1312 Epimerase k59_250950_1 1045854.WKK_06255 2.92e-26 113.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,4AWH8@81850|Leuconostocaceae 91061|Bacilli L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k59_289342_1 1050202.KB913024_gene784 3.86e-05 50.4 COG0463@1|root,COG0463@2|Bacteria,2IG3X@201174|Actinobacteria 201174|Actinobacteria M Glycosyl transferase, family 2 - - - - - - - - - - - - Glycos_transf_2,PqqD k59_215501_1 445696.E3ST04_9CAUD 3.79e-101 325.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QHVQ@10662|Myoviridae 10662|Myoviridae S nucleotide binding - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016032,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019058,GO:0019079,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0039686,GO:0039693,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044403,GO:0044419,GO:0046483,GO:0051704,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_215501_2 1150989.H6WXG4_9CAUD 9.76e-16 78.2 4QG24@10239|Viruses,4QV8E@35237|dsDNA viruses no RNA stage,4QSGP@28883|Caudovirales,4QM3Q@10699|Siphoviridae 10699|Siphoviridae S (deoxy)nucleoside-phosphate kinase activity - GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0044237,GO:0047507 - - - - - - - - - - - k59_141724_2 643867.Ftrac_0413 1.29e-11 65.5 2DMPB@1|root,32SV8@2|Bacteria,4NSG4@976|Bacteroidetes,47SFC@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_32713_2 1150864.MILUP08_41212 3.22e-05 48.9 COG3409@1|root,COG3409@2|Bacteria,2HBCJ@201174|Actinobacteria,4DAUU@85008|Micromonosporales 201174|Actinobacteria M Peptidase M15 - - 3.4.17.14 ko:K08640 - - - - ko00000,ko01000,ko01002,ko01011 - - - PG_binding_1,Peptidase_M15_3 k59_324442_3 1278311.AUAL01000001_gene79 5.69e-05 47.0 COG0568@1|root,COG0568@2|Bacteria,3WSV5@544448|Tenericutes 544448|Tenericutes K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k59_275309_1 477974.Daud_1705 4.18e-06 52.8 COG0250@1|root,COG0250@2|Bacteria 2|Bacteria K Participates in transcription elongation, termination and antitermination nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02601,ko:K05785 - - - - ko00000,ko03000,ko03009,ko03021 - - - KOW,NusG k59_129884_2 1137799.GZ78_25410 4.12e-13 68.2 2DPB2@1|root,331BY@2|Bacteria,1NBDA@1224|Proteobacteria,1SD6C@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_384159_1 1150626.PHAMO_210201 2.53e-11 65.5 2C9JF@1|root,32RPD@2|Bacteria,1N8CG@1224|Proteobacteria 1224|Proteobacteria S ERF superfamily - - - - - - - - - - - - ERF k59_238616_4 1609634.A0A0C5AFV4_9VIRU 2.33e-19 87.4 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_165971_1 1379692.S5SXY7_9CIRC 2.01e-26 110.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_262735_2 1385658.U5KPZ6_9VIRU 1.16e-41 151.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_129887_1 742740.HMPREF9474_02278 4.32e-07 52.4 28JED@1|root,2Z98K@2|Bacteria,1TW1U@1239|Firmicutes,24CFD@186801|Clostridia,2226E@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - GerE k59_251111_3 313612.L8106_13505 1.14e-10 68.2 COG3926@1|root,COG4990@1|root,COG3926@2|Bacteria,COG4990@2|Bacteria,1GHGJ@1117|Cyanobacteria 1117|Cyanobacteria S Peptidase_C39 like family - - - - - - - - - - - - Glyco_hydro_108,Peptidase_C39_2 k59_166085_2 261292.Nit79A3_1464 9.58e-19 82.0 2E4R2@1|root,32ZJM@2|Bacteria,1N9RQ@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_32923_1 1088721.NSU_0749 5.16e-43 149.0 COG3935@1|root,COG3935@2|Bacteria,1NK3U@1224|Proteobacteria,2UM2I@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DnaD domain protein - - - - - - - - - - - - - k59_32923_2 292414.TM1040_1678 1.44e-12 66.6 COG4570@1|root,COG4570@2|Bacteria,1PKG9@1224|Proteobacteria,2UJJJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC - - - - - - - - - - - - - k59_8183_1 268748.Q58N34_BPPRP 5.52e-18 89.0 4QBAU@10239|Viruses,4QW8E@35237|dsDNA viruses no RNA stage,4QPEP@28883|Caudovirales,4QNY1@10744|Podoviridae 10744|Podoviridae S viral capsid assembly - - - - - - - - - - - - - k59_56830_1 1609634.A0A0C5AFV4_9VIRU 2.13e-157 462.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_251115_3 269796.Rru_A1278 3.49e-10 62.4 28N1N@1|root,2ZB7Q@2|Bacteria,1R86T@1224|Proteobacteria,2U0A6@28211|Alphaproteobacteria,2JRMI@204441|Rhodospirillales 204441|Rhodospirillales H Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_1 k59_240081_4 3750.XP_008352071.1 5.37e-05 54.7 COG0553@1|root,KOG1001@2759|Eukaryota,37IVF@33090|Viridiplantae,3G7HD@35493|Streptophyta,4JDHA@91835|fabids 35493|Streptophyta KL SWI SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3-like - - 2.3.2.27 ko:K15711 - - - - ko00000,ko01000,ko03400,ko04121 - - - HIRAN,Helicase_C,SNF2_N,zf-C3HC4,zf-C3HC4_3 k59_167337_1 1519464.HY22_09210 4.34e-08 59.3 COG0451@1|root,COG0451@2|Bacteria 2|Bacteria GM ADP-glyceromanno-heptose 6-epimerase activity - - 5.1.3.10,5.1.3.2 ko:K01784,ko:K12454 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984,R04266 RC00289,RC00528 ko00000,ko00001,ko00002,ko01000 - - - Epimerase k59_167337_2 316055.RPE_1511 8.41e-25 104.0 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,2TRCN@28211|Alphaproteobacteria,3JTVF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - - - - - - - - - - CTP_transf_like,PfkB k59_385592_1 105154.Q9MBU3_9VIRU 2.67e-10 64.3 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_217422_1 1788454.A0A190WHE4_9CIRC 7.44e-40 142.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_217422_2 1379711.S5SYC9_9CIRC 4.67e-15 78.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_131830_1 556269.ACDQ01000003_gene1345 9.83e-46 162.0 COG4653@1|root,COG4653@2|Bacteria,1MWU1@1224|Proteobacteria,2VP0D@28216|Betaproteobacteria,478AT@75682|Oxalobacteraceae 28216|Betaproteobacteria S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_95879_1 1408417.JHYB01000003_gene182 0.000165 52.8 COG0210@1|root,COG0210@2|Bacteria,3WT08@544448|Tenericutes 544448|Tenericutes L DNA helicase pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k59_167558_1 411460.RUMTOR_01356 2.15e-97 312.0 28JED@1|root,2Z98K@2|Bacteria,1TW1U@1239|Firmicutes,24CFD@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - GerE k59_290854_1 1234888.K0A2J2_9VIRU 2.22e-45 165.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_131833_1 1463857.JOFZ01000001_gene5947 2.01e-16 82.8 COG0270@1|root,COG0270@2|Bacteria,2GK6Z@201174|Actinobacteria 201174|Actinobacteria L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_240332_1 933262.AXAM01000071_gene2218 3.42e-15 77.0 28XPA@1|root,2ZJK5@2|Bacteria,1P9T2@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_278561_4 420246.GTNG_1153 1.9e-13 68.9 COG2359@1|root,COG2359@2|Bacteria,1V6G8@1239|Firmicutes,4HIQV@91061|Bacilli,1WGP8@129337|Geobacillus 91061|Bacilli S Stage V sporulation protein S (SpoVS) spoVS - - ko:K06416 - - - - ko00000 - - - SpoVS k59_254435_1 1385658.U5KPZ6_9VIRU 2.22e-61 205.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_254435_3 1165094.RINTHH_3920 7.47e-89 275.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_254435_5 10855.H_SPV4 4.41e-06 52.4 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_254435_6 105154.Q9MBU6_9VIRU 1.29e-149 441.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_157782_1 11082.PRO_0000037746 1.94e-68 223.0 4QBXT@10239|Viruses,4R138@439488|ssRNA viruses,4R0R1@35278|ssRNA positive-strand viruses no DNA stage 10239|Viruses K ATP-dependent helicase activity - GO:0001510,GO:0001959,GO:0001960,GO:0002682,GO:0002683,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003725,GO:0003727,GO:0003824,GO:0004482,GO:0004483,GO:0005488,GO:0005575,GO:0006139,GO:0006370,GO:0006396,GO:0006397,GO:0006508,GO:0006725,GO:0006807,GO:0006810,GO:0006897,GO:0006898,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008171,GO:0008173,GO:0008174,GO:0008233,GO:0008757,GO:0009451,GO:0009452,GO:0009605,GO:0009607,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009968,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010646,GO:0010648,GO:0010941,GO:0016032,GO:0016070,GO:0016071,GO:0016192,GO:0016556,GO:0016740,GO:0016741,GO:0016787,GO:0018995,GO:0019012,GO:0019031,GO:0019048,GO:0019049,GO:0019050,GO:0019054,GO:0019058,GO:0019065,GO:0019068,GO:0019219,GO:0019222,GO:0019538,GO:0020012,GO:0023051,GO:0023057,GO:0030260,GO:0030430,GO:0030682,GO:0030683,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031347,GO:0031348,GO:0032259,GO:0032991,GO:0032993,GO:0033592,GO:0033643,GO:0033646,GO:0033655,GO:0033668,GO:0034641,GO:0035821,GO:0036260,GO:0036265,GO:0036338,GO:0039502,GO:0039503,GO:0039526,GO:0039713,GO:0039714,GO:0042981,GO:0043067,GO:0043069,GO:0043170,GO:0043207,GO:0043412,GO:0043414,GO:0043487,GO:0043489,GO:0043656,GO:0043657,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044068,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044403,GO:0044409,GO:0044413,GO:0044414,GO:0044415,GO:0044419,GO:0044423,GO:0044501,GO:0044531,GO:0044532,GO:0044766,GO:0045069,GO:0045070,GO:0045088,GO:0045824,GO:0045934,GO:0046483,GO:0046718,GO:0046755,GO:0046762,GO:0046794,GO:0048518,GO:0048519,GO:0048523,GO:0048524,GO:0048583,GO:0048585,GO:0050690,GO:0050776,GO:0050777,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051252,GO:0051253,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051806,GO:0051807,GO:0051817,GO:0051828,GO:0051832,GO:0051833,GO:0051834,GO:0052027,GO:0052029,GO:0052031,GO:0052037,GO:0052040,GO:0052041,GO:0052150,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052248,GO:0052250,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052433,GO:0052490,GO:0052493,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0060147,GO:0060149,GO:0060255,GO:0060338,GO:0060339,GO:0060548,GO:0060759,GO:0060761,GO:0060966,GO:0060967,GO:0060968,GO:0060969,GO:0065007,GO:0065008,GO:0071704,GO:0072583,GO:0075109,GO:0075111,GO:0075112,GO:0075114,GO:0075136,GO:0075509,GO:0075512,GO:0075528,GO:0080009,GO:0080090,GO:0080134,GO:0090304,GO:0097159,GO:0097617,GO:0098657,GO:0106005,GO:0140096,GO:0140098,GO:1900368,GO:1900369,GO:1901360,GO:1901363,GO:1901564,GO:1902369,GO:1902579,GO:1903900,GO:1903902,GO:1990814,GO:1990904 - - - - - - - - - - - k59_11098_1 439375.Oant_0240 1.2e-22 101.0 COG4653@1|root,COG4653@2|Bacteria,1Q3BS@1224|Proteobacteria,2TW86@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage major capsid protein - - - - - - - - - - - - Phage_capsid k59_108645_2 929562.Emtol_0759 5.23e-18 87.4 COG0553@1|root,COG0553@2|Bacteria,4NKAA@976|Bacteroidetes,47MHC@768503|Cytophagia 976|Bacteroidetes KL COGs COG0553 Superfamily II DNA RNA helicase SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_278568_2 1120963.KB894501_gene316 1.52e-28 107.0 COG2852@1|root,COG2852@2|Bacteria,1N7EJ@1224|Proteobacteria,1SF5D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - DUF559 k59_48162_1 227086.JGI_V11_91559 5.24e-07 57.0 COG0553@1|root,KOG1000@2759|Eukaryota 2759|Eukaryota L annealing helicase activity - - 3.6.4.12 ko:K14440 - - - - ko00000,ko01000,ko03036 - - - Helicase_C,SNF2_N,zf-GRF k59_363346_1 268746.Q58ML2_BPPRM 3.21e-36 139.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QI9F@10662|Myoviridae 10662|Myoviridae S Type III restriction enzyme, res subunit - - - - - - - - - - - - - k59_182218_1 189753.AXAS01000085_gene6030 1.43e-08 52.4 2EG1N@1|root,339TN@2|Bacteria 2|Bacteria S prophage protein Bartonella henselae str. Houston-1 gi 49237922 emb CAF27125.1 - - - - - - - - - - - - PTR k59_255577_3 645099.MREP_BBTVA 5.2e-14 79.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_24799_3 713586.KB900537_gene3383 1.49e-68 230.0 2DCM2@1|root,32TZV@2|Bacteria,1NAGE@1224|Proteobacteria,1SMRS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_352988_1 311403.Arad_2297 2.42e-84 264.0 COG4653@1|root,COG4653@2|Bacteria,1R76W@1224|Proteobacteria,2TTD3@28211|Alphaproteobacteria,4BN89@82115|Rhizobiaceae 28211|Alphaproteobacteria S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_207219_1 1618259.A0A0C5I2B5_9CIRC 3.4e-26 105.0 4QE84@10239|Viruses,4QUKR@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_182663_1 1234888.K0A2J2_9VIRU 3.22e-25 106.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_231389_4 268407.PWYN_23795 2.11e-06 48.9 COG4186@1|root,COG4186@2|Bacteria,1V6DG@1239|Firmicutes,4HPXG@91061|Bacilli,26VH5@186822|Paenibacillaceae 91061|Bacilli S Phosphoesterase - - - - - - - - - - - - Metallophos,Metallophos_2 k59_109898_1 652103.Rpdx1_2524 3.5e-16 79.0 2EP91@1|root,33GVT@2|Bacteria,1NHCT@1224|Proteobacteria,2UJY7@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_122104_1 2003327.CAPSD_BPCHP 9.59e-23 103.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_12591_1 1385658.U5KPZ6_9VIRU 5.36e-15 75.1 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_639_3 313596.RB2501_01256 7.67e-05 42.7 COG3108@1|root,COG3108@2|Bacteria,4NV14@976|Bacteroidetes,1I63W@117743|Flavobacteriia 976|Bacteroidetes S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k59_364953_2 1609634.A0A0C5ANA6_9VIRU 1.35e-15 80.9 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_364953_3 1609634.A0A0C5AFV4_9VIRU 6.59e-112 349.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_243396_5 1247726.MIM_c15240 8.52e-07 57.0 COG0859@1|root,COG0859@2|Bacteria,1PMN2@1224|Proteobacteria,2VTS5@28216|Betaproteobacteria,3T1S8@506|Alcaligenaceae 28216|Betaproteobacteria M heptosyltransferase waaF - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 k59_377296_2 598467.BrE312_2408 1.06e-14 75.1 COG3566@1|root,COG3566@2|Bacteria,1RAWB@1224|Proteobacteria,1SZWV@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2213) - - - ko:K09960 - - - - ko00000 - - - DUF2213 k59_316500_2 1692249.A0A0K1RL40_9CIRC 1.31e-76 240.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_12967_1 1088721.NSU_0760 1.56e-18 88.2 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,2TT3N@28211|Alphaproteobacteria,2K7A3@204457|Sphingomonadales 204457|Sphingomonadales S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_49789_1 666684.AfiDRAFT_3723 7.9e-11 68.9 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2TS2G@28211|Alphaproteobacteria,3JWPH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k59_280944_1 1692249.A0A0K1RLN8_9CIRC 9.68e-32 123.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_220036_1 479434.Sthe_1140 2.94e-13 74.7 COG0399@1|root,COG0399@2|Bacteria,2G7J4@200795|Chloroflexi 200795|Chloroflexi E Belongs to the DegT DnrJ EryC1 family - - - - - - - - - - - - DegT_DnrJ_EryC1 k59_110466_2 1121413.JMKT01000011_gene2318 2.7e-38 137.0 29UKS@1|root,30FY7@2|Bacteria,1RGKW@1224|Proteobacteria,430C2@68525|delta/epsilon subdivisions,2WW6K@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_317068_4 1136731.J9PTU9_9CAUD 6.06e-08 60.8 4QASV@10239|Viruses,4QWD9@35237|dsDNA viruses no RNA stage,4QQ4N@28883|Caudovirales,4QIBN@10662|Myoviridae 10662|Myoviridae S recA bacterial DNA recombination protein - - - - - - - - - - - - - k59_122675_1 1385658.U5KPZ6_9VIRU 7.48e-108 329.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_122675_6 1385658.U5KNR1_9VIRU 3.54e-43 154.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_74067_2 1986029.Q9MBM3_9VIRU 1.29e-23 103.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_365378_2 1197951.I6S6J6_9CAUD 1.08e-09 63.5 4QH2I@10239|Viruses,4QWWD@35237|dsDNA viruses no RNA stage,4QQE9@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_243963_1 717605.Theco_4114 5.9e-13 71.6 COG0338@1|root,COG0338@2|Bacteria,1UBIY@1239|Firmicutes,4HDX1@91061|Bacilli,26V5F@186822|Paenibacillaceae 91061|Bacilli L D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_378281_2 96561.Dole_1885 1.92e-141 462.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,2MI79@213118|Desulfobacterales 28221|Deltaproteobacteria L DNA polymerase III alpha subunit dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k59_378281_3 536232.CLM_2557 2.41e-05 48.1 COG1694@1|root,COG1694@2|Bacteria 2|Bacteria FG Mazg nucleotide pyrophosphohydrolase - - - - - - - - - - - - MazG k59_378281_4 314254.OA2633_04776 2.24e-32 131.0 COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2TRPR@28211|Alphaproteobacteria,43W8I@69657|Hyphomonadaceae 28211|Alphaproteobacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071496 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA k59_25877_1 665950.HMPREF1025_01581 2.11e-25 117.0 COG5362@1|root,COG5362@2|Bacteria,1TSQB@1239|Firmicutes,24ACE@186801|Clostridia 186801|Clostridia S TIGRFAM Phage - - - - - - - - - - - - - k59_25877_18 504832.OCAR_7567 1.14e-30 138.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,3JRVT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_25877_21 97139.C824_03620 1.1e-12 76.6 COG0863@1|root,COG0863@2|Bacteria,1TRDZ@1239|Firmicutes,249ZT@186801|Clostridia 186801|Clostridia L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_25877_24 331678.Cphamn1_1726 2.3e-41 145.0 COG0847@1|root,COG0847@2|Bacteria,1FF0V@1090|Chlorobi 1090|Chlorobi L PFAM Exonuclease RNase T and DNA polymerase III - - - - - - - - - - - - RNase_T k59_208470_1 1121441.AUCX01000007_gene1212 5.4e-09 63.2 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,2M7UN@213115|Desulfovibrionales 28221|Deltaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_74657_1 1177181.T9A_00229 3.44e-26 109.0 COG2946@1|root,COG2946@2|Bacteria,1RDKM@1224|Proteobacteria,1S7EJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Replication initiation factor - - - - - - - - - - - - Rep_trans k59_341838_2 428125.CLOLEP_01412 4.01e-42 153.0 28JK5@1|root,2Z9D1@2|Bacteria,1UJZJ@1239|Firmicutes,24D64@186801|Clostridia,3WMZ3@541000|Ruminococcaceae 186801|Clostridia S Caudovirus prohead serine protease - - - - - - - - - - - - Peptidase_S78 k59_196147_1 1176422.I6R1A2_9CAUD 2.33e-96 296.0 4QEVG@10239|Viruses,4QYM0@35237|dsDNA viruses no RNA stage,4QRJD@28883|Caudovirales,4QMNF@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_98907_1 1560342.A0A0A0RMR6_9CAUD 1.36e-06 55.5 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QI32@10662|Myoviridae 10662|Myoviridae S DNA polymerase family A - - - - - - - - - - - - - k59_38074_1 742925.D4N3R4_9CIRC 3.27e-20 93.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_171820_1 1127692.HMPREF9075_00026 9.28e-22 100.0 COG1196@1|root,COG3941@1|root,COG1196@2|Bacteria,COG3941@2|Bacteria,4NF3E@976|Bacteroidetes,1I066@117743|Flavobacteriia,1ERB7@1016|Capnocytophaga 976|Bacteroidetes D Tape measure domain protein - - - - - - - - - - - - - k59_329895_1 530564.Psta_0913 1.43e-70 231.0 2FANA@1|root,342W0@2|Bacteria,2J3AN@203682|Planctomycetes 203682|Planctomycetes S Phage major capsid protein E - - - - - - - - - - - - Phage_cap_E k59_1746_1 156889.Mmc1_1716 8.97e-57 189.0 28NGF@1|root,2ZBII@2|Bacteria,1R9KY@1224|Proteobacteria,2U1P7@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_366017_3 1391034.T1YRW5_9VIRU 1.07e-44 159.0 4QAZA@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_341839_1 1609634.A0A0C5AFV4_9VIRU 1.88e-106 328.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_245052_2 652103.Rpdx1_2520 3.11e-69 249.0 COG2268@1|root,COG2268@2|Bacteria,1NT13@1224|Proteobacteria,2U335@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Band 7 protein - - - - - - - - - - - - - k59_245052_3 243275.TDE_1157 1.64e-90 290.0 COG1783@1|root,COG1783@2|Bacteria 2|Bacteria S DNA packaging - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_6 k59_366553_1 113395.AXAI01000008_gene1041 0.000172 43.1 2CYA9@1|root,32T3V@2|Bacteria,1RGRN@1224|Proteobacteria,2U90D@28211|Alphaproteobacteria,3JZUP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_366553_5 504346.B5WZW3_BPPAJ 7.2e-23 95.5 4QCB0@10239|Viruses,4QX81@35237|dsDNA viruses no RNA stage,4QPFH@28883|Caudovirales,4QKQY@10699|Siphoviridae 10699|Siphoviridae S YqaJ-like viral recombinase domain - - - - - - - - - - - - - k59_172455_2 2754.EH55_08555 1.11e-45 179.0 COG4643@1|root,COG5545@1|root,COG4643@2|Bacteria,COG5545@2|Bacteria 2|Bacteria P DNA integration - - - ko:K06919 - - - - ko00000 - - - PriCT_2,Toprim_3,Toprim_4,VirE,VirE_N k59_330641_1 1536592.A0A088F717_9VIRU 1.96e-05 51.6 4QFEB@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_378891_1 1379713.S5SYD9_9CIRC 1.3e-27 114.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_50949_3 145579.B_BPPHM 2.87e-17 80.1 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_50949_4 145579.H_BPPHM 1.24e-13 73.6 4QCA6@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_50949_5 1609634.A0A0C5AFV4_9VIRU 2.18e-10 60.5 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_233144_1 1463841.JOIR01000035_gene7223 2.52e-42 154.0 COG1215@1|root,COG4627@1|root,COG1215@2|Bacteria,COG4627@2|Bacteria,2IAZU@201174|Actinobacteria 201174|Actinobacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2,Methyltransf_11 k59_50951_2 1609634.A0A0C5AFV4_9VIRU 6.78e-82 261.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_196864_1 212035.YL364_MIMIV 1.44e-49 187.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage 10239|Viruses S N-methyltransferase activity - GO:0005575,GO:0019012 - - - - - - - - - - - k59_147974_1 1234888.K0A2J2_9VIRU 2.16e-72 233.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_330645_1 428125.CLOLEP_01423 1.65e-60 199.0 2E2JP@1|root,32XP4@2|Bacteria,1VAIM@1239|Firmicutes,24PPR@186801|Clostridia,3WI4W@541000|Ruminococcaceae 186801|Clostridia S Phage tail protein - - - - - - - - - - - - Sipho_tail k59_69877_2 870967.VIS19158_15149 2.03e-14 68.2 2AXTD@1|root,31PUC@2|Bacteria,1QMHD@1224|Proteobacteria,1TJSR@1236|Gammaproteobacteria,1Y1MU@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k59_117771_1 583345.Mmol_0235 6.62e-16 83.6 COG1475@1|root,COG4725@1|root,COG1475@2|Bacteria,COG4725@2|Bacteria,1R553@1224|Proteobacteria,2WFIC@28216|Betaproteobacteria 28216|Betaproteobacteria KT Belongs to the MT-A70-like family - - - - - - - - - - - - MT-A70,ParBc k59_325333_1 1589298.A0A0B5GYS4_9CAUD 1.32e-99 303.0 4QC2G@10239|Viruses,4QPRR@28883|Caudovirales,4QM50@10699|Siphoviridae 10699|Siphoviridae S Ribonucleotide reductase, small chain - - - - - - - - - - - - - k59_188191_1 469618.FVAG_01342 6.2e-13 74.7 COG2870@1|root,COG2870@2|Bacteria,378KV@32066|Fusobacteria 32066|Fusobacteria M Psort location Cytoplasmic, score rfaE1 - - - - - - - - - - - PfkB k59_276112_1 1121468.AUBR01000104_gene3117 3.73e-41 152.0 COG0863@1|root,COG0863@2|Bacteria,1TR56@1239|Firmicutes,248NR@186801|Clostridia 186801|Clostridia L Belongs to the N(4) N(6)-methyltransferase family cfr9IM - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_105912_3 1385658.U5KPZ6_9VIRU 5.19e-87 275.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_385012_1 145579.CAPSD_BPPHM 3.71e-27 115.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_81981_3 1165094.RINTHH_3920 9.07e-69 222.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_142734_2 365046.Rta_33080 5.24e-21 95.5 COG3405@1|root,COG3405@2|Bacteria,1QZE5@1224|Proteobacteria,2W62R@28216|Betaproteobacteria,4AIQV@80864|Comamonadaceae 28216|Betaproteobacteria G Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - - - - - - - - - - - k59_19798_2 1088721.NSU_0767 2.36e-08 63.9 2EG1N@1|root,339TN@2|Bacteria,1NEFY@1224|Proteobacteria,2UGTQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S prophage protein Bartonella henselae str. Houston-1 gi 49237922 emb CAF27125.1 - - - - - - - - - - - - - k59_251849_2 1121456.ATVA01000014_gene632 6.55e-32 126.0 COG1783@1|root,COG1783@2|Bacteria,1RAGC@1224|Proteobacteria,42Z29@68525|delta/epsilon subdivisions,2WTUP@28221|Deltaproteobacteria,2MCJK@213115|Desulfovibrionales 28221|Deltaproteobacteria S phage Terminase large subunit - - - - - - - - - - - - - k59_69971_1 1382315.JPOI01000001_gene2076 3.8e-20 96.3 COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,4HA1H@91061|Bacilli,1WFT1@129337|Geobacillus 91061|Bacilli E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k59_156014_2 1220717.L7TNH6_9VIRU 1.42e-55 192.0 4QAKZ@10239|Viruses 10239|Viruses S N-acetyltransferase activity - - - - - - - - - - - - - k59_9539_1 105154.Q9MBU6_9VIRU 1.6e-61 206.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_252742_2 1692253.A0A0K1RLM4_9CIRC 1.14e-15 84.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_229368_1 631362.Thi970DRAFT_03408 1.1e-08 59.7 COG4627@1|root,COG4627@2|Bacteria,1N2HA@1224|Proteobacteria,1SJB1@1236|Gammaproteobacteria 1236|Gammaproteobacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Methyltransf_11 k59_82988_1 743721.Psesu_1175 9.05e-19 92.8 2DNH7@1|root,32XH1@2|Bacteria,1RHPW@1224|Proteobacteria,1T56U@1236|Gammaproteobacteria,1X3WB@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k59_20779_1 868864.Dester_0102 0.00097 42.0 COG0863@1|root,COG2189@1|root,COG0863@2|Bacteria,COG2189@2|Bacteria,2G4CN@200783|Aquificae 200783|Aquificae L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_20779_2 1392540.P256_00045 4.77e-27 102.0 2BRZC@1|root,32KZQ@2|Bacteria,1Q31I@1224|Proteobacteria,1RSVN@1236|Gammaproteobacteria,3NRT9@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_350254_1 655097.C8ZKH6_9CAUD 6.78e-17 81.3 4QBYE@10239|Viruses,4QVYH@35237|dsDNA viruses no RNA stage,4QQTP@28883|Caudovirales,4QP46@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_58497_1 2003327.CAPSD_BPCHP 1.75e-22 108.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_34670_1 1218076.BAYB01000015_gene3200 2.84e-17 85.1 COG0305@1|root,COG0305@2|Bacteria,1PP51@1224|Proteobacteria,2VQ9Z@28216|Betaproteobacteria 28216|Betaproteobacteria L DnaB-like helicase C terminal domain - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - AAA_25,DnaB_C k59_167631_1 78398.KS43_20490 7.97e-33 130.0 COG0553@1|root,COG0553@2|Bacteria 2|Bacteria L helicase activity - - - - - - - - - - - - Helicase_C,SNF2_N k59_375000_5 665950.HMPREF1025_01581 3.02e-24 114.0 COG5362@1|root,COG5362@2|Bacteria,1TSQB@1239|Firmicutes,24ACE@186801|Clostridia 186801|Clostridia S TIGRFAM Phage - - - - - - - - - - - - - k59_97051_1 247156.PNF1_100 1.47e-10 66.6 COG0270@1|root,COG0270@2|Bacteria,2GJS2@201174|Actinobacteria,4FYE0@85025|Nocardiaceae 201174|Actinobacteria L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_386848_1 145579.REP_BPPHM 4.59e-44 159.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_218592_1 349161.Dred_1192 3.33e-54 187.0 COG0553@1|root,COG0553@2|Bacteria,1TP2C@1239|Firmicutes,24DVA@186801|Clostridia 186801|Clostridia L DEAD-like helicases superfamily - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_35579_2 1120963.KB894518_gene2794 3.5e-50 193.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,1S0Q1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L ORF located using Glimmer RBSfinder - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_230343_1 105154.Q9MBU0_9VIRU 1.18e-32 125.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_386851_1 627192.SLG_22000 2.02e-53 181.0 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,2TV42@28211|Alphaproteobacteria,2K7D4@204457|Sphingomonadales 204457|Sphingomonadales S TIGRFAM phage terminase, large subunit, PBSX family - - - ko:K06909 - - - - ko00000 - - - Terminase_3 k59_21702_2 582899.Hden_0147 1.02e-23 100.0 2DP75@1|root,330U8@2|Bacteria,1N8XA@1224|Proteobacteria,2UIHW@28211|Alphaproteobacteria 28211|Alphaproteobacteria L PFAM Pathogenesis-related transcriptional factor and ERF protein - - - - - - - - - - - - AP2,HNH_3 k59_327394_23 34506.g5961 5.89e-06 55.5 COG1278@1|root,KOG3070@2759|Eukaryota,3ABXI@33154|Opisthokonta,3BVM8@33208|Metazoa,3DI7P@33213|Bilateria 33208|Metazoa J Cold shock protein domain - - - - - - - - - - - - CSD,Phage_antitermQ k59_266141_3 1211115.ALIQ01000044_gene2940 3.78e-38 143.0 COG5449@1|root,COG5449@2|Bacteria,1MXK2@1224|Proteobacteria,2V9HD@28211|Alphaproteobacteria,3N9WR@45404|Beijerinckiaceae 28211|Alphaproteobacteria S Phage conserved hypothetical protein BR0599 - - - - - - - - - - - - DUF2163,Phage_BR0599 k59_315443_1 1218075.BAYA01000001_gene421 1.33e-35 136.0 28PTM@1|root,2ZCEU@2|Bacteria,1R5DD@1224|Proteobacteria,2W259@28216|Betaproteobacteria 28216|Betaproteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_157922_1 396588.Tgr7_0386 6.53e-58 200.0 COG1345@1|root,COG1345@2|Bacteria,1QZZ9@1224|Proteobacteria 1224|Proteobacteria N Prophage tail length tape measure protein - - - - - - - - - - - - TMP_2 k59_254539_1 1000569.HMPREF1040_0208 1.94e-32 133.0 COG2887@1|root,COG2887@2|Bacteria,1TPIC@1239|Firmicutes,4H2UC@909932|Negativicutes 909932|Negativicutes L Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - DUF2800 k59_254539_2 78398.KS43_20455 1.75e-40 142.0 28J2E@1|root,2Z8YX@2|Bacteria,1REPW@1224|Proteobacteria,1S4IX@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2815) - - - - - - - - - - - - DUF2815 k59_254539_3 1274524.BSONL12_06038 5.44e-50 184.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,4H9Z7@91061|Bacilli,1ZEKP@1386|Bacillus 91061|Bacilli L DNA polymerase A domain - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_351929_1 502025.Hoch_4662 1.81e-11 65.5 COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42MAI@68525|delta/epsilon subdivisions,2WJ8M@28221|Deltaproteobacteria,2YV5P@29|Myxococcales 28221|Deltaproteobacteria J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17,6.1.1.24 ko:K01885,ko:K09698 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c k59_351929_2 515635.Dtur_1020 6.09e-30 119.0 COG0449@1|root,COG0449@2|Bacteria 2|Bacteria M glutamine-fructose-6-phosphate transaminase (isomerizing) activity glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iAF987.Gmet_1487,iE2348C_1286.E2348C_4039,iEC042_1314.EC042_4115,iECIAI39_1322.ECIAI39_4333,iECNA114_1301.ECNA114_3878,iECOK1_1307.ECOK1_4178,iECSF_1327.ECSF_3577,iECUMN_1333.ECUMN_4259,iEcSMS35_1347.EcSMS35_4097,iIT341.HP1532,iLF82_1304.LF82_0844,iNJ661.Rv3436c,iNRG857_1313.NRG857_18570,iSB619.SA_RS11245,iSFV_1184.SFV_3755,iSF_1195.SF3809,iSFxv_1172.SFxv_4151,iS_1188.S3959,iUMN146_1321.UM146_18835,iUTI89_1310.UTI89_C4281,iYO844.BSU01780 GATase_6,SIS k59_205986_2 1540097.A0A0A0YRN0_9CAUD 1.07e-77 258.0 4QF3C@10239|Viruses,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_266154_1 756272.Plabr_0190 0.000348 43.5 COG1357@1|root,COG1357@2|Bacteria,2J1MR@203682|Planctomycetes 203682|Planctomycetes S Pentapeptide repeats (9 copies) - - - - - - - - - - - - Pentapeptide k59_315602_1 105154.Q9MBU3_9VIRU 3e-11 63.9 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_206091_1 247490.KSU1_C1497 3.4e-05 53.9 COG4373@1|root,COG4373@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Terminase_6,Terminase_6C k59_206091_4 1556290.A0A0A0RQK4_9CAUD 1.4e-17 76.6 4QHNZ@10239|Viruses,4QRCH@28883|Caudovirales,4QMHT@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_206091_6 649831.L083_1589 2.92e-35 150.0 COG1372@1|root,COG1702@1|root,COG1372@2|Bacteria,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,4DC9N@85008|Micromonosporales 201174|Actinobacteria T PhoH-like protein phoH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K06217 - - - - ko00000 - - - PhoH k59_278721_3 234267.Acid_6941 2.46e-12 69.7 COG3064@1|root,COG4627@1|root,COG3064@2|Bacteria,COG4627@2|Bacteria 2|Bacteria M translation initiation factor activity - - - ko:K08307,ko:K19140 - - - - ko00000,ko01000,ko01011,ko02048 - - - DDE_Tnp_1,DUF772,Methyltransf_11 k59_72815_1 580331.Thit_1406 1.53e-12 71.6 COG3723@1|root,COG3723@2|Bacteria,1UNDF@1239|Firmicutes,24CI5@186801|Clostridia 186801|Clostridia L RecT family recT - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_352061_1 145579.CAPSD_BPPHM 1.69e-84 268.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_352061_3 1165094.RINTHH_3920 6.35e-62 204.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_352061_6 105154.Q9MBU3_9VIRU 6.67e-18 85.1 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_352061_7 105154.Q9MBU6_9VIRU 7.02e-129 385.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_11417_2 1437882.AZRU01000111_gene4952 8.76e-29 115.0 28J3M@1|root,2Z8ZT@2|Bacteria,1Q2A4@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - PDDEXK_1 k59_254678_1 1463901.JOIY01000021_gene5369 1.19e-07 61.6 COG1061@1|root,COG1061@2|Bacteria 2|Bacteria L Type III restriction enzyme res subunit - - - - - - - - - - - - Helicase_C,ResIII k59_109021_1 1692249.A0A0K1RL40_9CIRC 2.64e-36 131.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_120572_1 1250005.PHEL85_2452 1.67e-38 149.0 COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1HXHB@117743|Flavobacteriia,3VVTA@52959|Polaribacter 976|Bacteroidetes F Ribonucleotide reductase, all-alpha domain nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k59_193925_1 1209989.TepiRe1_2626 8.11e-21 99.8 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,42I55@68295|Thermoanaerobacterales 186801|Clostridia H DNA polymerase A domain - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_193956_1 1234888.K0A2J2_9VIRU 5.96e-107 325.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_193956_6 105154.Q9MBU0_9VIRU 6.6e-27 114.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_193956_7 1234888.K0A2J2_9VIRU 3.4e-62 209.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_194084_1 145579.REP_BPPHM 7.66e-07 52.8 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_194109_2 1618248.A0A0C5IB82_9CIRC 4.17e-17 87.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_194148_1 1096546.WYO_0201 1.55e-170 511.0 28P6A@1|root,2ZC10@2|Bacteria,1RBZE@1224|Proteobacteria,2UQEG@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_194148_4 1046714.AMRX01000006_gene3191 4.48e-22 96.3 28JC4@1|root,2Z96S@2|Bacteria,1RI8W@1224|Proteobacteria,1S6FI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S P22 coat protein-protein 5 domain protein - - - - - - - - - - - - - k59_194206_1 1692255.A0A0K1RL52_9CIRC 5.74e-13 72.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_207221_1 1161931.J7FA60_9CAUD 4.71e-37 143.0 4QB9Y@10239|Viruses,4QWGZ@35237|dsDNA viruses no RNA stage,4QPTT@28883|Caudovirales,4QJD7@10662|Myoviridae 10662|Myoviridae S hydrolase activity - - - - - - - - - - - - - k59_364931_2 1385658.U5KPZ6_9VIRU 1.46e-63 223.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_365273_1 1234888.K0A2J2_9VIRU 5.23e-80 255.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_110354_3 1385935.N836_35740 1.4e-23 96.7 COG0270@1|root,COG0270@2|Bacteria,1GE2G@1117|Cyanobacteria,1HFNE@1150|Oscillatoriales 1117|Cyanobacteria L C-5 cytosine-specific DNA methylase - - - - - - - - - - - - DNA_methylase k59_98158_1 105154.Q9MBU3_9VIRU 1.32e-07 57.8 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_256106_2 1120705.FG95_00895 1.23e-20 99.8 COG1475@1|root,COG1475@2|Bacteria,1MVF9@1224|Proteobacteria,2TR0P@28211|Alphaproteobacteria,2K1WS@204457|Sphingomonadales 204457|Sphingomonadales K partitioning protein, ParB - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_195280_1 1379709.S5TMV0_9CIRC 5.04e-73 229.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_316924_1 1403819.BATR01000081_gene2296 3.84e-21 99.8 COG4675@1|root,COG4675@2|Bacteria 2|Bacteria M tail collar domain protein - - - - - - - - - - - - Collar k59_85964_3 145579.CAPSD_BPPHM 6.57e-80 263.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_122562_1 1215092.PA6_009_00220 9.03e-31 126.0 291GM@1|root,2ZP3A@2|Bacteria,1RD1E@1224|Proteobacteria,1S4X6@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_146882_1 1158150.KB906242_gene233 1.34e-63 213.0 COG5410@1|root,COG5410@2|Bacteria,1N0W2@1224|Proteobacteria 1224|Proteobacteria K chromosome segregation - - - - - - - - - - - - - k59_110359_1 1121459.AQXE01000001_gene2748 1.77e-33 122.0 2AGTB@1|root,3171D@2|Bacteria,1RJGM@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - DUF2833 k59_243893_3 10732.K4HYT8_9CAUD 8.75e-30 119.0 4QGJD@10239|Viruses,4R0CG@35237|dsDNA viruses no RNA stage,4QU69@28883|Caudovirales,4QKQQ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_159104_2 1147.D082_16180 8.49e-18 90.5 COG0582@1|root,COG0582@2|Bacteria,1GHVX@1117|Cyanobacteria,1H61F@1142|Synechocystis 1117|Cyanobacteria L Phage integrase, N-terminal SAM-like domain xerC - - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k59_159104_6 1003195.SCAT_0615 1.98e-53 178.0 28MC2@1|root,2ZAQD@2|Bacteria,2IKMZ@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_316991_1 1122243.KB903788_gene33 7.32e-11 68.9 COG1196@1|root,COG5281@1|root,COG1196@2|Bacteria,COG5281@2|Bacteria,1MX2R@1224|Proteobacteria,1S3MM@1236|Gammaproteobacteria,3NSS7@468|Moraxellaceae 1236|Gammaproteobacteria D tape measure protein Z012_10445 - - - - - - - - - - - Phage_HK97_TLTM,Tape_meas_lam_C k59_122627_2 935837.JAEK01000054_gene1465 4.38e-46 171.0 COG4373@1|root,COG4373@2|Bacteria,1TQNK@1239|Firmicutes,4HDES@91061|Bacilli,1ZBVH@1386|Bacillus 91061|Bacilli S Mu-like prophage FluMu protein gp28 gp17a - - - - - - - - - - - Terminase_6,Terminase_6C k59_147404_6 439235.Dalk_1773 4.3e-06 48.1 COG2161@1|root,COG2161@2|Bacteria,1N07B@1224|Proteobacteria,42UIW@68525|delta/epsilon subdivisions,2WQU3@28221|Deltaproteobacteria,2MKSY@213118|Desulfobacterales 28221|Deltaproteobacteria D Antitoxin component of a toxin-antitoxin (TA) module - - - - - - - - - - - - PhdYeFM_antitox k59_147404_7 65093.PCC7418_0319 3.88e-27 100.0 2C16Q@1|root,330H3@2|Bacteria,1G90Z@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - HicB,RHH_1 k59_147404_8 715451.ambt_15655 1.64e-58 184.0 COG1569@1|root,COG1569@2|Bacteria,1N1T4@1224|Proteobacteria,1S7J5@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Toxin-antitoxin system, toxin component, PIN family - - - - - - - - - - - - PIN_3 k59_147404_13 1417599.U6C697_9CAUD 2.92e-42 164.0 4QBFN@10239|Viruses,4QXWN@35237|dsDNA viruses no RNA stage,4QPTW@28883|Caudovirales,4QNPZ@10744|Podoviridae 10744|Podoviridae S Phage stabilisation protein - - - - - - - - - - - - - k59_1637_1 2003327.CAPSD_BPCHP 7.7e-34 137.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_196028_1 1692244.A0A0K1RLR5_9CIRC 1.82e-49 167.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_317754_2 697281.Mahau_2489 4.7e-19 94.0 2ECUP@1|root,336S6@2|Bacteria,1VIQ7@1239|Firmicutes,252T4@186801|Clostridia,42IN8@68295|Thermoanaerobacterales 186801|Clostridia - - - - - - - - - - - - - - - k59_208423_4 186617.M9M8L2_9VIRU 2.45e-64 212.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_329792_4 595460.RRSWK_03363 1.7e-104 324.0 COG3306@1|root,COG3551@1|root,COG3306@2|Bacteria,COG3551@2|Bacteria,2J3XB@203682|Planctomycetes 203682|Planctomycetes M glycosyltransferase involved in LPS biosynthesis - - - - - - - - - - - - Glyco_transf_25 k59_329792_6 525909.Afer_1971 3.98e-08 59.3 COG0463@1|root,COG1216@1|root,COG0463@2|Bacteria,COG1216@2|Bacteria,2HG1R@201174|Actinobacteria,4CMYI@84992|Acidimicrobiia 84992|Acidimicrobiia M Glycosyltransferase like family 2 - - - ko:K20444 - - - - ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 - Glycos_transf_2 k59_220616_3 546264.NEIFLAOT_00952 9.54e-44 158.0 COG4128@1|root,COG4128@2|Bacteria,1R51Y@1224|Proteobacteria,2VIPX@28216|Betaproteobacteria,2KRCQ@206351|Neisseriales 206351|Neisseriales S Zonular occludens toxin (Zot) - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_341727_2 1692256.A0A0K1RL85_9CIRC 5.86e-89 274.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_13333_1 1385658.U5KPZ6_9VIRU 9.41e-160 470.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_281650_1 315456.RF_1239 2.42e-10 65.9 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,47F10@766|Rickettsiales 766|Rickettsiales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_75160_1 1385658.U5KPZ6_9VIRU 1.08e-69 229.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_282560_2 347834.RHE_CH01097 2.16e-56 187.0 28NGF@1|root,2ZBII@2|Bacteria,1R9KY@1224|Proteobacteria,2U1P7@28211|Alphaproteobacteria,4B747@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_2312_2 1609634.A0A0C5ANA6_9VIRU 0.000181 49.3 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_63342_1 34506.g5960 1.16e-24 108.0 COG3040@1|root,KOG4824@2759|Eukaryota,3AQKQ@33154|Opisthokonta,3C2XJ@33208|Metazoa,3DI0Q@33213|Bilateria 33208|Metazoa M Lipocalin-like domain - - - ko:K03098 - - - - ko00000,ko04147 - - - Lipocalin_2 k59_209266_4 272568.GDI3670 7e-61 220.0 COG0234@1|root,COG0234@2|Bacteria,1NJKP@1224|Proteobacteria,2UM25@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter - - - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - - k59_221375_1 691965.D4P7C5_9CAUD 6.2e-141 417.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_196870_2 1231190.NA8A_14741 6.77e-29 112.0 COG4678@1|root,COG4678@2|Bacteria,1RJEK@1224|Proteobacteria,2U9UF@28211|Alphaproteobacteria,43N2Z@69277|Phyllobacteriaceae 28211|Alphaproteobacteria G Muramidase (Phage lambda lysozyme) - - - - - - - - - - - - - k59_282589_1 1379722.S5SY31_9CIRC 1.24e-46 157.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_318573_2 1000565.METUNv1_01729 3.27e-81 261.0 COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,2VIFH@28216|Betaproteobacteria,2KX72@206389|Rhodocyclales 206389|Rhodocyclales H C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_319134_1 649639.Bcell_2721 1.69e-53 191.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,4HGW7@91061|Bacilli,1ZBWW@1386|Bacillus 91061|Bacilli D phage tail tape measure protein - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,SLT k59_245623_1 2003327.CAPSD_BPCHP 7.05e-50 177.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_269990_1 2003327.CAPSD_BPCHP 9.78e-20 88.6 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_245733_1 511051.CSE_02370 2.8e-11 76.6 COG4733@1|root,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - - - - - - - - - - - Big_5,CW_binding_2,Glyco_hydro_48,SLH,fn3 k59_161082_2 1385658.U5KPZ6_9VIRU 4.08e-210 600.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_3163_1 1123399.AQVE01000045_gene3190 4.56e-23 101.0 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,1RQFD@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage terminase, large subunit Z012_12305 - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_27297_1 927704.SELR_18440 2.96e-09 63.5 COG3935@1|root,COG3935@2|Bacteria,1TQ65@1239|Firmicutes,4H6KQ@909932|Negativicutes 909932|Negativicutes L N-terminal phage replisome organiser (Phage_rep_org_N) - - - - - - - - - - - - Phage_rep_org_N k59_319227_1 886293.Sinac_6305 0.000849 50.1 COG1216@1|root,COG4122@1|root,COG1216@2|Bacteria,COG4122@2|Bacteria,2IYW7@203682|Planctomycetes 203682|Planctomycetes S O-methyltransferase activity - - - - - - - - - - - - Methyltransf_24 k59_331385_1 1122962.AULH01000017_gene92 1.19e-31 115.0 2CJWR@1|root,33Y76@2|Bacteria,1N250@1224|Proteobacteria,2UDF1@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_331385_2 1528098.NOVO_00420 2.73e-08 58.9 2AJ3M@1|root,319N0@2|Bacteria,1Q39Q@1224|Proteobacteria,2UKWC@28211|Alphaproteobacteria,47FRA@766|Rickettsiales 766|Rickettsiales S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 k59_331385_3 649639.Bcell_2100 8.89e-13 66.6 COG5614@1|root,COG5614@2|Bacteria,1UAZR@1239|Firmicutes,4IMCK@91061|Bacilli,1ZJT9@1386|Bacillus 91061|Bacilli S Phage head-tail joining protein - - - - - - - - - - - - Phage_H_T_join k59_295352_7 1385658.U5KPZ6_9VIRU 5.84e-110 334.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_332126_2 1692247.A0A0K1RL30_9CIRC 1.31e-25 110.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_39805_1 913970.F8RW84_9VIRU 1.39e-09 65.1 4QCVK@10239|Viruses,4QUMV@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_307644_2 1450694.BTS2_0497 4.61e-32 115.0 2CDFK@1|root,2Z8BH@2|Bacteria,1V43D@1239|Firmicutes,4HY70@91061|Bacilli 91061|Bacilli S DNA N-6-adenine-methyltransferase (Dam) - - - - - - - - - - - - Dam k59_380335_1 573174.M4MCV1_9VIRU 4.68e-25 110.0 4QAKZ@10239|Viruses,4QUSW@35237|dsDNA viruses no RNA stage 10239|Viruses S N-acetyltransferase activity - - - - - - - - - - - - - k59_161836_1 1197951.I6RT34_9CAUD 3.51e-130 386.0 4QGAG@10239|Viruses,4R0KB@35237|dsDNA viruses no RNA stage,4QUA4@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_161836_2 979533.F1D0V0_9CAUD 8.39e-35 134.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales,4QNDH@10744|Podoviridae 10744|Podoviridae S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_14966_1 1788447.A0A190WHJ9_9CIRC 4.56e-89 271.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_332134_1 1234888.K0A2J2_9VIRU 1.09e-48 172.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_137154_1 1410620.SHLA_15c001200 9.24e-43 143.0 2C58H@1|root,32YYI@2|Bacteria,1N7UA@1224|Proteobacteria,2UHCE@28211|Alphaproteobacteria,4BHYU@82115|Rhizobiaceae 28211|Alphaproteobacteria S NinB protein - - - - - - - - - - - - NinB k59_137154_6 196490.AUEZ01000004_gene4030 5.64e-150 432.0 COG1032@1|root,COG1032@2|Bacteria,1NG4M@1224|Proteobacteria,2UKY8@28211|Alphaproteobacteria 28211|Alphaproteobacteria C radical SAM domain protein - - - - - - - - - - - - - k59_367910_2 1788449.A0A190WHL0_9CIRC 6.97e-32 124.0 4QBFZ@10239|Viruses,4QUKU@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_270838_1 1211777.BN77_4169 5.01e-37 139.0 2C5GI@1|root,2Z8C1@2|Bacteria,1R8XM@1224|Proteobacteria,2TUME@28211|Alphaproteobacteria,4BJKS@82115|Rhizobiaceae 28211|Alphaproteobacteria S P22 coat protein - gene protein 5 - - - - - - - - - - - - P22_CoatProtein k59_125509_3 2003327.CAPSD_BPCHP 1.06e-77 262.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_356043_13 663241.C9E2I7_9CAUD 1.88e-48 178.0 4QFE9@10239|Viruses,4QYP9@35237|dsDNA viruses no RNA stage,4QQZT@28883|Caudovirales,4QMZ7@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_319955_1 742918.D4N3P2_9CIRC 5.9e-25 103.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_88827_1 317655.Sala_2518 1.47e-33 129.0 COG1363@1|root,COG1363@2|Bacteria,1MYM4@1224|Proteobacteria,2UR0H@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Evidence 4 Homologs of previously reported genes of - - - - - - - - - - - - Peptidase_M28 k59_184794_2 1123325.JHUV01000009_gene299 2.63e-06 57.8 COG0741@1|root,COG0741@2|Bacteria,2G442@200783|Aquificae 200783|Aquificae M Lytic transglycosylase catalytic - - - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT k59_271621_1 352165.HMPREF7215_2558 1.68e-10 67.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria 2|Bacteria L DNA primase activity - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - AAA_25,DUF3987,DnaB_C,Toprim_2,Toprim_4 k59_259413_2 1828.JOKB01000010_gene5308 8.54e-21 84.7 2BQQI@1|root,32JM2@2|Bacteria,2GYV9@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_150202_3 1692249.A0A0K1RLN8_9CIRC 7.02e-26 107.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_15666_3 1538804.A0A088F6T3_9CAUD 7.39e-10 60.5 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_211552_1 145579.REP_BPPHM 1.98e-20 94.4 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_356781_2 1692255.A0A0K1RL52_9CIRC 5.83e-10 67.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_77280_1 145579.CAPSD_BPPHM 4.35e-17 85.5 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_296075_1 1150626.PHAMO_280117 7.34e-62 209.0 COG0305@1|root,COG0305@2|Bacteria,1QYEE@1224|Proteobacteria,2TVH2@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - AAA_25,DnaB_C,Toprim_2 k59_320728_1 2003327.CAPSD_BPCHP 8.1e-65 216.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_113627_1 640081.Dsui_0206 9.46e-08 55.1 COG5449@1|root,COG5449@2|Bacteria,1MXK2@1224|Proteobacteria,2VSPS@28216|Betaproteobacteria,2KZ3U@206389|Rhodocyclales 206389|Rhodocyclales S Phage conserved hypothetical protein BR0599 - - - - - - - - - - - - DUF2163,Phage_BR0599 k59_15667_2 1219035.NT2_13_00580 1.38e-67 227.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_174797_3 1101190.ARWB01000001_gene2218 1.31e-24 101.0 COG3409@1|root,COG4322@1|root,COG3409@2|Bacteria,COG4322@2|Bacteria,1R4RS@1224|Proteobacteria,2TYJ9@28211|Alphaproteobacteria 28211|Alphaproteobacteria M CHAP domain - - - - - - - - - - - - CHAP,PG_binding_1 k59_150214_1 742740.HMPREF9474_02310 1.9e-16 81.3 2A0KC@1|root,2ZGJK@2|Bacteria,1V2JS@1239|Firmicutes,24H6R@186801|Clostridia,222B7@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_308472_3 742733.HMPREF9469_05027 1.12e-21 89.0 2E6F6@1|root,3312K@2|Bacteria,1VFHE@1239|Firmicutes,24SVA@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_332843_4 679197.HMPREF9336_02209 1.07e-15 75.9 COG4626@1|root,COG4626@2|Bacteria,2GNSB@201174|Actinobacteria 201174|Actinobacteria S Terminase - - - - - - - - - - - - - k59_40687_3 1385658.U5KNR1_9VIRU 5.65e-40 148.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_4766_3 1168478.I6R9L9_9CAUD 7.57e-43 163.0 4QCHV@10239|Viruses,4QUW9@35237|dsDNA viruses no RNA stage,4QQEZ@28883|Caudovirales,4QMEA@10699|Siphoviridae 10699|Siphoviridae S Virulence-associated protein E - - - - - - - - - - - - - k59_53162_2 460265.Mnod_4078 1.73e-156 458.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria,1JZ7Y@119045|Methylobacteriaceae 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_53162_3 1439940.BAY1663_02340 4.05e-112 345.0 COG3740@1|root,COG3740@2|Bacteria,1QVIJ@1224|Proteobacteria,1T44Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Caudovirus prohead serine protease - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78,Phage_capsid k59_381777_1 1219035.NT2_13_00600 1.27e-26 110.0 290X3@1|root,2ZNIW@2|Bacteria,1P7TA@1224|Proteobacteria,2UXFQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_29852_3 1234888.K0A2J2_9VIRU 2.11e-27 110.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_309256_1 1234888.K0A2J2_9VIRU 8.23e-22 99.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_345553_2 1082931.KKY_773 3.38e-14 74.3 28JTG@1|root,2Z7PY@2|Bacteria,1QVNY@1224|Proteobacteria,2TXVN@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_78236_1 593750.Metfor_0428 1.31e-41 150.0 COG0451@1|root,arCOG04627@2157|Archaea,2XW3U@28890|Euryarchaeota 28890|Euryarchaeota M Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction fcl - 1.1.1.271,4.2.1.46 ko:K01710,ko:K02377 ko00051,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00051,map00520,map00521,map00523,map00525,map01055,map01100,map01130 M00793 R05692,R06513 RC00402,RC01014 ko00000,ko00001,ko00002,ko01000 - - - Epimerase k59_175661_1 1147139.A0A0A6Z5B7_9CAUD 2.76e-54 202.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_138948_2 1173028.ANKO01000014_gene1061 1.81e-07 57.4 COG4122@1|root,COG4122@2|Bacteria,1G5B0@1117|Cyanobacteria,1HB99@1150|Oscillatoriales 1117|Cyanobacteria S Methyltransferase domain - - - - - - - - - - - - Methyltransf_24,TPR_2 k59_224428_1 1609634.A0A0C5AFT2_9VIRU 2.89e-31 119.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_114351_5 1788452.A0A190WHG0_9CIRC 3.83e-25 105.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_78247_2 652103.Rpdx1_2982 1.76e-21 96.3 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT50@1224|Proteobacteria,2TTND@28211|Alphaproteobacteria,3JW9V@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L TOPRIM - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - AAA_25,DnaB_C,Toprim_2,Toprim_4 k59_176626_1 679926.Mpet_2297 3.6e-33 131.0 COG0863@1|root,arCOG00115@2157|Archaea,2Y00D@28890|Euryarchaeota 28890|Euryarchaeota L modification methylase - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_225363_4 1121943.KB900008_gene1990 7.14e-08 55.5 2ER6M@1|root,33IS8@2|Bacteria,1NIM1@1224|Proteobacteria,1SU18@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_225363_5 1249627.D779_2292 5e-30 128.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1R97W@1224|Proteobacteria,1TK9M@1236|Gammaproteobacteria,1X0PG@135613|Chromatiales 135613|Chromatiales D Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_42523_1 1502770.JQMG01000001_gene2157 2.07e-30 126.0 COG0740@1|root,COG0740@2|Bacteria,1MUQ9@1224|Proteobacteria,2W9XP@28216|Betaproteobacteria,2KP1K@206350|Nitrosomonadales 206350|Nitrosomonadales OU Belongs to the peptidase S14 family - - - - - - - - - - - - - k59_287371_1 76869.PputGB1_1760 2.05e-56 200.0 28IJ1@1|root,2Z8K0@2|Bacteria,1R5PC@1224|Proteobacteria,1S1ER@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_17223_4 1618247.A0A0C5I2K0_9CIRC 7.22e-20 92.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_164298_1 1122963.AUHB01000026_gene1118 1.8e-17 84.7 COG3723@1|root,COG3723@2|Bacteria,1R6DB@1224|Proteobacteria,2U82T@28211|Alphaproteobacteria 28211|Alphaproteobacteria L RecT family - - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_79261_2 384616.Pisl_1504 7.73e-05 50.1 COG0451@1|root,arCOG01369@2157|Archaea,2XQCJ@28889|Crenarchaeota 28889|Crenarchaeota M PFAM NAD-dependent epimerase dehydratase - - 4.1.1.35,5.1.3.2 ko:K01784,ko:K08678 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R01384,R02984 RC00289,RC00508 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd k59_260955_1 626418.bglu_1g15240 2.15e-25 98.6 2E04N@1|root,32VT5@2|Bacteria,1N310@1224|Proteobacteria,2W2JF@28216|Betaproteobacteria,1K8RJ@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_186949_2 240016.ABIZ01000001_gene824 1.16e-119 379.0 COG0859@1|root,COG0859@2|Bacteria,46TJT@74201|Verrucomicrobia 74201|Verrucomicrobia M Glycosyltransferase family 9 (heptosyltransferase) - - - - - - - - - - - - Glyco_transf_9,Mannosyl_trans3 k59_311076_1 1088721.NSU_0767 1.08e-08 62.4 2EG1N@1|root,339TN@2|Bacteria,1NEFY@1224|Proteobacteria,2UGTQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S prophage protein Bartonella henselae str. Houston-1 gi 49237922 emb CAF27125.1 - - - - - - - - - - - - - k59_226493_1 1100720.ALKN01000018_gene1738 2.54e-11 70.1 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,2VQF3@28216|Betaproteobacteria,4ADUP@80864|Comamonadaceae 28216|Betaproteobacteria L Helicase conserved C-terminal domain - - - - - - - - - - - - Helicase_C,ResIII,UPF0547 k59_226493_2 1454007.JAUG01000005_gene2805 1.65e-09 61.2 COG0270@1|root,COG0270@2|Bacteria,4NJPP@976|Bacteroidetes,1IYYG@117747|Sphingobacteriia 976|Bacteroidetes L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_335515_2 1175654.A0A0S0N897_9CAUD 5.12e-40 148.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_250122_3 1121022.ABENE_17600 9e-70 228.0 2CDQ7@1|root,2Z7KV@2|Bacteria,1MY2D@1224|Proteobacteria,2TR92@28211|Alphaproteobacteria,2KHVY@204458|Caulobacterales 204458|Caulobacterales - - - - - - - - - - - - - - - k59_43590_1 46234.ANA_C13754 3.76e-11 64.7 COG0720@1|root,COG0720@2|Bacteria,1GKBI@1117|Cyanobacteria,1HSIJ@1161|Nostocales 1117|Cyanobacteria H 6-pyruvoyl tetrahydropterin synthase - - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS k59_237794_1 1380380.JIAX01000015_gene2956 8.7e-09 62.0 COG0553@1|root,COG0553@2|Bacteria,1MXQH@1224|Proteobacteria,2TR5V@28211|Alphaproteobacteria 28211|Alphaproteobacteria KL methylase - - - - - - - - - - - - AAA_34,Helicase_C_4 k59_7373_1 1536770.R50345_20080 1.58e-28 124.0 COG5297@1|root,COG5297@2|Bacteria,1V1T2@1239|Firmicutes,4HUDU@91061|Bacilli,26S1Z@186822|Paenibacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase family 6 guxA - 3.2.1.91 ko:K19668 ko00500,ko01100,ko02020,map00500,map01100,map02020 - R02886,R11308 RC00799 ko00000,ko00001,ko01000 - GH6 - CBM_3,Glyco_hydro_6,fn3 k59_31880_1 1609634.A0A0C5AFT2_9VIRU 2.71e-23 99.4 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_80270_1 7176.CPIJ008169-PA 4.86e-11 62.4 2E4T1@1|root,2SBN4@2759|Eukaryota,3ADG2@33154|Opisthokonta,3BWF0@33208|Metazoa,3DCTZ@33213|Bilateria 33208|Metazoa - - - - - - - - - - - - - - - k59_55835_2 1123279.ATUS01000005_gene3102 3.64e-37 142.0 2CJWY@1|root,31CWF@2|Bacteria,1RKEF@1224|Proteobacteria,1S75P@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_140970_2 1475062.W8TKM5_9CIRC 2.05e-07 60.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_274581_2 330214.NIDE2235 8.64e-14 82.8 COG3299@1|root,COG3299@2|Bacteria 2|Bacteria S Baseplate J-like protein yqbT1 - - - - - - - - - - - Baseplate_J k59_324800_1 105422.BBPM01000058_gene4616 4.31e-48 170.0 COG1475@1|root,COG4422@1|root,COG1475@2|Bacteria,COG4422@2|Bacteria,2IAY7@201174|Actinobacteria,2NK47@228398|Streptacidiphilus 201174|Actinobacteria K DNA binding - - - - - - - - - - - - ParBc k59_372456_1 1618248.A0A0C5IB82_9CIRC 2.57e-09 60.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_348796_2 1618242.A0A0C5IBR9_9CIRC 7.21e-40 144.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_33066_3 760568.Desku_0904 1.37e-32 127.0 2EI39@1|root,33BUS@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_238934_1 273526.SMDB11_2873 7.89e-05 49.3 COG3108@1|root,COG3108@2|Bacteria,1RICX@1224|Proteobacteria,1S6D5@1236|Gammaproteobacteria,4039B@613|Serratia 1236|Gammaproteobacteria S D-alanyl-D-alanine carboxypeptidase - - - ko:K17733 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M15_4 k59_300624_1 504346.B5WZR8_BPPAJ 5.25e-92 285.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_81383_3 1379725.S5SYG4_9CIRC 1.46e-51 175.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_187795_2 717785.HYPMC_1248 0.000396 51.6 2E983@1|root,333GI@2|Bacteria,1N8C3@1224|Proteobacteria,2UITX@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_215783_1 742740.HMPREF9474_01203 8.08e-09 62.4 COG5280@1|root,COG5283@1|root,COG5412@1|root,COG5280@2|Bacteria,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia,21YY2@1506553|Lachnoclostridium 186801|Clostridia M Phage tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail,TMP k59_105386_1 649743.HMPREF0972_01394 4.16e-09 67.0 COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GM2E@201174|Actinobacteria,4D3HI@85005|Actinomycetales 201174|Actinobacteria L Belongs to the helicase family. UvrD subfamily uvrD2 - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k59_105386_12 906968.Trebr_1735 1.46e-14 78.2 COG1475@1|root,COG1475@2|Bacteria,2J7KN@203691|Spirochaetes 203691|Spirochaetes K ParB-like nuclease domain - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_227766_1 2003327.CAPSD_BPCHP 1.45e-35 140.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_301727_1 1692259.A0A0K1RL59_9CIRC 1.91e-20 98.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_143155_1 1609634.A0A0C5AFT2_9VIRU 2.32e-25 104.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_349718_3 445693.E3SND3_9CAUD 8.35e-17 94.4 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNBD@10744|Podoviridae 10744|Podoviridae S outer membrane - - - - - - - - - - - - - k59_349718_7 1117318.PRUB_07920 2.09e-111 334.0 COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,1RP7G@1236|Gammaproteobacteria,2PZT5@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006139,GO:0006629,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045226,GO:0046379,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576,GO:1903509 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - iB21_1397.B21_01936,iECBD_1354.ECBD_1614,iECB_1328.ECB_01947,iECD_1391.ECD_01947,iECIAI39_1322.ECIAI39_0974,iECNA114_1301.ECNA114_3926,iECO26_1355.ECO26_2952,iECSF_1327.ECSF_1930,iECSF_1327.ECSF_3628 GDP_Man_Dehyd k59_349718_9 709991.Odosp_0822 1.98e-49 162.0 2BVF9@1|root,32QUP@2|Bacteria,4NS32@976|Bacteroidetes,2FSIF@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_349718_13 658187.LDG_6143 9.67e-26 122.0 COG0467@1|root,COG1119@1|root,COG0467@2|Bacteria,COG1119@2|Bacteria 2|Bacteria P ATPase activity - - - ko:K03546,ko:K06919,ko:K07452,ko:K08482,ko:K09384,ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko01000,ko02042,ko02048,ko03400 - - - AAA_11,AAA_12,AAA_25,DUF4011 k59_349718_14 202752.JL53_00675 1.33e-53 202.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,4H9Z7@91061|Bacilli,26MH2@186820|Listeriaceae 91061|Bacilli L DNA polymerase A domain polA_2 - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_349718_16 1280671.AUJH01000012_gene3168 3.87e-15 84.3 COG2887@1|root,COG2887@2|Bacteria,1TPIC@1239|Firmicutes,247TB@186801|Clostridia,4C0KN@830|Butyrivibrio 186801|Clostridia L Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_349718_17 930166.CD58_10310 9.45e-17 79.3 COG0317@1|root,COG0317@2|Bacteria,1N2BZ@1224|Proteobacteria,1SB8N@1236|Gammaproteobacteria 1236|Gammaproteobacteria KT HD domain - - - - - - - - - - - - HD_4 k59_349718_23 469616.FMAG_00317 1.2e-06 60.1 COG0553@1|root,COG0553@2|Bacteria,3788I@32066|Fusobacteria 32066|Fusobacteria L Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - Helicase_C,SNF2_N k59_203830_1 504472.Slin_5973 5.08e-56 199.0 COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,47K9B@768503|Cytophagia 976|Bacteroidetes L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k59_167146_2 1121926.AXWO01000004_gene1187 1.68e-14 74.7 2B815@1|root,3218Y@2|Bacteria,2H57E@201174|Actinobacteria 201174|Actinobacteria S Rad52/22 family double-strand break repair protein - - - - - - - - - - - - Rad52_Rad22 k59_155559_2 1618237.A0A0C5IMG6_9CIRC 6.02e-21 100.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_131319_1 1469245.JFBG01000066_gene130 4.26e-37 131.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_228942_1 526226.Gbro_1350 2.05e-06 52.8 COG1051@1|root,COG1051@2|Bacteria,2IQEU@201174|Actinobacteria,4GEZ3@85026|Gordoniaceae 201174|Actinobacteria F NUDIX domain - - - - - - - - - - - - NUDIX k59_240011_1 1041147.AUFB01000014_gene357 1.11e-08 62.4 COG5519@1|root,COG5519@2|Bacteria,1QU3K@1224|Proteobacteria,2TVXZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Bifunctional DNA primase/polymerase, N-terminal - - - - - - - - - - - - DUF3987,Prim-Pol k59_106590_3 1120934.KB894459_gene1381 2.53e-49 170.0 COG0639@1|root,COG0639@2|Bacteria,2GMS4@201174|Actinobacteria,4E9IG@85010|Pseudonocardiales 201174|Actinobacteria T Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos,Metallophos_2 k59_264160_2 525368.HMPREF0591_3583 2.01e-05 49.3 COG1396@1|root,COG1396@2|Bacteria,2IKVI@201174|Actinobacteria,2398E@1762|Mycobacteriaceae 201174|Actinobacteria K transcriptional - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - - - - - - - - - - HTH_3,HTH_31 k59_264160_6 1382304.JNIL01000001_gene195 2.82e-27 110.0 COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli,2789Y@186823|Alicyclobacillaceae 91061|Bacilli E Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - RadC k59_326038_1 488538.SAR116_1492 7.15e-05 46.2 COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,2TTX6@28211|Alphaproteobacteria,4BRBF@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S RmuC family rmuC - - ko:K09760 - - - - ko00000 - - - RmuC k59_156816_1 392499.Swit_4440 1.35e-59 195.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,2U1P9@28211|Alphaproteobacteria,2KAJR@204457|Sphingomonadales 204457|Sphingomonadales S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6C k59_314486_1 643867.Ftrac_1814 1.01e-129 392.0 COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,47JEH@768503|Cytophagia 976|Bacteroidetes F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN k59_132615_1 1453503.AU05_17305 3.02e-31 132.0 2E983@1|root,333GI@2|Bacteria,1N8C3@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_119375_2 1162295.I1TRA9_9CAUD 8.42e-19 88.6 4QCMK@10239|Viruses,4QUPQ@35237|dsDNA viruses no RNA stage,4QS1R@28883|Caudovirales,4QKCR@10662|Myoviridae 10662|Myoviridae S methyltransferase activity - - - - - - - - - - - - - k59_386563_1 312309.VF_0074 1.03e-11 76.6 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1XUAZ@135623|Vibrionales 135623|Vibrionales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_132623_1 1484158.PSNIH1_00490 3.42e-40 150.0 COG5323@1|root,COG5410@1|root,COG5323@2|Bacteria,COG5410@2|Bacteria,1MW8S@1224|Proteobacteria,1SYQD@1236|Gammaproteobacteria,3W1VF@53335|Pantoea 1236|Gammaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6C k59_339111_1 1123367.C666_04180 1.21e-49 185.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2VJ57@28216|Betaproteobacteria,2KUC6@206389|Rhodocyclales 206389|Rhodocyclales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_339111_3 1127696.HMPREF9134_00463 1.42e-07 59.3 COG1100@1|root,COG1100@2|Bacteria,4NEXY@976|Bacteroidetes,2FRU5@200643|Bacteroidia,22ZUP@171551|Porphyromonadaceae 976|Bacteroidetes S AAA domain - - - - - - - - - - - - AAA_24 k59_230083_6 367336.OM2255_10695 5.66e-23 95.5 COG1432@1|root,COG1432@2|Bacteria,1MUAE@1224|Proteobacteria,2TU5M@28211|Alphaproteobacteria 28211|Alphaproteobacteria L NYN domain MA20_36560 - - - - - - - - - - - NYN k59_327157_1 1385658.U5KPZ6_9VIRU 2.52e-25 109.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_218285_1 1498011.A0A096XUV7_9CAUD 4.83e-51 179.0 4QB5I@10239|Viruses,4QPQ9@28883|Caudovirales,4QNX6@10744|Podoviridae 10744|Podoviridae S Helicase conserved C-terminal domain - - - - - - - - - - - - - k59_386574_1 1235661.K0ILM7_9CAUD 1.53e-102 319.0 4QD9Y@10239|Viruses,4QUXQ@35237|dsDNA viruses no RNA stage,4QTPE@28883|Caudovirales,4QNY4@10744|Podoviridae 10744|Podoviridae S Terminase-like family - - - - - - - - - - - - - k59_170140_2 1506572.A0A097ZPG0_9CIRC 1.51e-45 161.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_60781_2 1609634.A0A0C5ANA6_9VIRU 1.65e-29 116.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_72915_2 1144275.COCOR_01852 3.52e-53 177.0 COG2129@1|root,COG2129@2|Bacteria,1R3TH@1224|Proteobacteria 1224|Proteobacteria S phosphoesterases, related to the Icc protein - - - - - - - - - - - - Metallophos,Metallophos_2 k59_72915_3 1211844.CBLM010000098_gene1378 7.15e-10 67.8 COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,3VPQB@526524|Erysipelotrichia 526524|Erysipelotrichia L Phage integrase, N-terminal SAM-like domain - - - - - - - - - - - - Phage_int_SAM_1,Phage_integrase k59_328091_1 1128073.G9LQV6_9CIRC 3.05e-11 66.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_72921_1 1429767.W6AQV5_9CAUD 2.87e-63 220.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_97214_1 948071.S4S2D9_9CAUD 3.53e-162 479.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae 10744|Podoviridae S ribonucleoside-triphosphate reductase activity - - - - - - - - - - - - - k59_230891_1 1536592.A0A088F773_9VIRU 9.07e-53 186.0 4QB5I@10239|Viruses 10239|Viruses S N-methyltransferase activity - - - - - - - - - - - - - k59_24339_1 1234880.K0A2H8_9CIRC 2.57e-13 73.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_121526_4 1385658.U5KPZ6_9VIRU 1.71e-57 208.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_133692_1 691965.D4P7I3_9CAUD 4.27e-97 316.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_218767_1 1408442.JADE01000005_gene1098 0.000206 50.8 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2YM91@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_182300_1 1122223.KB890687_gene2833 3.16e-31 120.0 COG4422@1|root,COG4422@2|Bacteria,1WMFF@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Protein of unknown function (DUF5131) - - - - - - - - - - - - DUF5131 k59_122964_3 1029823.AFIE01000007_gene1892 6.61e-20 86.7 2DYV8@1|root,32V63@2|Bacteria,1QNWV@1224|Proteobacteria,1ST2X@1236|Gammaproteobacteria,3NNP1@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_37768_1 1082932.ATCR1_06741 7.17e-48 172.0 COG5323@1|root,COG5323@2|Bacteria,1R049@1224|Proteobacteria 1224|Proteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6 k59_353893_1 1986029.Q9MBM6_9VIRU 1.39e-19 86.3 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_123050_1 935261.JAGL01000009_gene1165 5.14e-87 278.0 COG0209@1|root,COG0209@2|Bacteria,1PM78@1224|Proteobacteria,2UZUM@28211|Alphaproteobacteria,43QGW@69277|Phyllobacteriaceae 28211|Alphaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - - - - - - - - - - - - k59_208199_2 105154.Q9MBU3_9VIRU 3.16e-07 58.2 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_50119_1 1609634.A0A0C5AFV4_9VIRU 8.57e-49 173.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_220422_1 1609634.A0A0C5AFT2_9VIRU 4.32e-92 280.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_50120_1 1408311.JNJM01000013_gene2333 2.72e-28 122.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,2PQWF@265975|Oribacterium 186801|Clostridia L Helix-hairpin-helix motif - - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k59_281419_1 742817.HMPREF9449_01798 5.13e-55 199.0 28IFC@1|root,2Z8H3@2|Bacteria,4NJUZ@976|Bacteroidetes,2FPHP@200643|Bacteroidia,22WYV@171551|Porphyromonadaceae 976|Bacteroidetes - - - - - - - - - - - - - - - k59_208205_1 365528.KB891217_gene1454 3.74e-94 286.0 COG0451@1|root,COG0451@2|Bacteria,2IDID@201174|Actinobacteria 201174|Actinobacteria GM GDP-mannose 4,6 dehydratase - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase k59_208205_2 702450.CUW_0019 2.06e-11 68.2 COG3774@1|root,COG3774@2|Bacteria,1V3YG@1239|Firmicutes,3VR8W@526524|Erysipelotrichia 526524|Erysipelotrichia M Glycosyltransferase sugar-binding region containing DXD motif - - - - - - - - - - - - Gly_transf_sug k59_208205_3 1123508.JH636439_gene1948 1.54e-12 64.7 2DRCN@1|root,33B89@2|Bacteria,2J3XX@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_74496_1 406817.XNC1_3146 2.6e-17 87.0 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,1RNAN@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Type III restriction protein res subunit yejH GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042221,GO:0042493,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051301,GO:0051716,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - ko:K19789 - - - - ko00000,ko03400 - - - Helicase_C,ResIII k59_329588_1 926569.ANT_31290 0.000311 50.8 COG0739@1|root,COG3103@1|root,COG0739@2|Bacteria,COG4991@2|Bacteria 2|Bacteria T sh3 domain protein - - 3.2.1.96 ko:K01227,ko:K03642 ko00511,map00511 - - - ko00000,ko00001,ko01000 - - - Glucosaminidase,NLPC_P60,Peptidase_M23,SH3_3,SLH k59_62428_1 691965.D4P7D6_9CAUD 5.24e-69 229.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_98632_5 742733.HMPREF9469_05074 1.26e-43 154.0 2A0KC@1|root,2ZGJK@2|Bacteria,1V2JS@1239|Firmicutes,24H6R@186801|Clostridia,222B7@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_87276_3 1524882.A0A076G8G2_9CAUD 2.44e-82 265.0 4QBXF@10239|Viruses,4QRDH@28883|Caudovirales,4QMR4@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_87276_5 911008.GLAD_00711 5.04e-51 181.0 COG1659@1|root,COG1659@2|Bacteria,1R0IH@1224|Proteobacteria,1T4F0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Linocin_M18 bacteriocin protein - - - - - - - - - - - - - k59_87276_7 866895.HBHAL_2430 2.9e-64 233.0 COG2931@1|root,COG2931@2|Bacteria,1TSGB@1239|Firmicutes,4HBZW@91061|Bacilli 91061|Bacilli Q Collagen triple helix repeat (20 copies) - - - - - - - - - - - - Collagen k59_124013_3 1304872.JAGC01000009_gene780 7.1e-20 87.4 2C6KN@1|root,32Y69@2|Bacteria,1N8AV@1224|Proteobacteria,433PH@68525|delta/epsilon subdivisions,2WX67@28221|Deltaproteobacteria,2ME4E@213115|Desulfovibrionales 28221|Deltaproteobacteria S VRR_NUC - - - - - - - - - - - - VRR_NUC k59_342400_2 1380394.JADL01000006_gene5258 7.57e-79 246.0 28NGF@1|root,2ZBII@2|Bacteria,1R9KY@1224|Proteobacteria,2U1P7@28211|Alphaproteobacteria,2JXPF@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_38477_2 1168059.KB899087_gene1184 1.04e-21 93.6 COG3409@1|root,COG3409@2|Bacteria,1REI1@1224|Proteobacteria,2U734@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_1 k59_269474_3 880071.Fleli_0590 4e-14 66.6 2BVK8@1|root,32Y0S@2|Bacteria,4NUUA@976|Bacteroidetes,47RXH@768503|Cytophagia 976|Bacteroidetes S Histone H1-like protein - - - - - - - - - - - - Hc1 k59_378838_1 546266.NEIMUCOT_03987 5.14e-08 59.3 2AUU3@1|root,31KH7@2|Bacteria,1RIUB@1224|Proteobacteria,2VQWT@28216|Betaproteobacteria,2KR1H@206351|Neisseriales 206351|Neisseriales - - - - - - - - - - - - - - - k59_147888_2 1122164.JHWF01000003_gene2091 5.21e-10 60.5 2D0K9@1|root,32T8S@2|Bacteria,1MZRW@1224|Proteobacteria,1SF0N@1236|Gammaproteobacteria,1JEKY@118969|Legionellales 118969|Legionellales - - - - - - - - - - - - - - - k59_209184_1 1618251.A0A0C5I2L8_9CIRC 5.15e-18 86.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_282485_1 1692257.A0A0K1RL39_9CIRC 2.3e-62 201.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_75112_1 645099.MREP_BBTVA 1.53e-12 72.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_26486_1 134676.ACPL_3476 0.000411 47.8 COG0467@1|root,COG0467@2|Bacteria,2I58C@201174|Actinobacteria,4DH7N@85008|Micromonosporales 201174|Actinobacteria T Circadian clock protein KaiC - - - ko:K08482 - - - - ko00000 - - - ATPase k59_99407_1 1215092.PA6_009_00300 1.25e-91 282.0 28JC4@1|root,2Z96S@2|Bacteria,1RI8W@1224|Proteobacteria,1S6FI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S P22 coat protein-protein 5 domain protein - - - - - - - - - - - - - k59_124190_1 1122612.AUBA01000004_gene456 4.41e-27 114.0 COG0507@1|root,COG0507@2|Bacteria,1R1AT@1224|Proteobacteria,2U1ZX@28211|Alphaproteobacteria 28211|Alphaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - - - - - - - - - - Terminase_6 k59_124919_2 1131814.JAFO01000001_gene2097 7.04e-29 129.0 COG3206@1|root,COG3206@2|Bacteria 2|Bacteria M extracellular polysaccharide biosynthetic process - - - ko:K06994 - - - - ko00000 - - - DUF4407,MMPL,Peptidase_S46,Wzz k59_124919_3 488538.SAR116_0376 6.34e-189 558.0 COG3064@1|root,COG3064@2|Bacteria,1R6JV@1224|Proteobacteria,2U5NE@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Membrane - - - - - - - - - - - - - k59_124919_6 488538.SAR116_0374 1.61e-42 157.0 2EGM1@1|root,33AD7@2|Bacteria,1NKQP@1224|Proteobacteria,2UKNH@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_124919_7 652103.Rpdx1_2955 3.22e-38 137.0 28PTM@1|root,2ZCEU@2|Bacteria,1R5DD@1224|Proteobacteria,2TVG7@28211|Alphaproteobacteria,3JU4C@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_379746_2 1219035.NT2_01_03930 5.01e-05 48.1 2C69U@1|root,32STX@2|Bacteria,1RDUC@1224|Proteobacteria,2U7XY@28211|Alphaproteobacteria,2K4F1@204457|Sphingomonadales 204457|Sphingomonadales S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_173240_4 1161401.ASJA01000008_gene1658 6.82e-07 55.8 2CJWY@1|root,33MF9@2|Bacteria,1NKUU@1224|Proteobacteria,2UMVZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_173240_7 1430440.MGMSRv2_3476 4.26e-45 157.0 COG1442@1|root,COG1442@2|Bacteria,1QH4S@1224|Proteobacteria,2U2NZ@28211|Alphaproteobacteria,2JTII@204441|Rhodospirillales 204441|Rhodospirillales M glycosyl transferase family 8 - - - - - - - - - - - - - k59_270240_1 999550.KI421507_gene3095 7.35e-15 80.5 COG0463@1|root,COG0463@2|Bacteria,1R4XG@1224|Proteobacteria,2TZ9Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 k59_331531_1 716928.AJQT01000109_gene1178 2.94e-43 157.0 COG0553@1|root,COG0553@2|Bacteria,1R7CK@1224|Proteobacteria,2U228@28211|Alphaproteobacteria,4BN0G@82115|Rhizobiaceae 28211|Alphaproteobacteria KL DNA methylase N-4 - - - - - - - - - - - - Helicase_C,N6_N4_Mtase k59_148753_2 911008.GLAD_04458 1.14e-07 54.3 28KZZ@1|root,2ZAF4@2|Bacteria,1R6SC@1224|Proteobacteria,1RR2K@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF1367) - - - - - - - - - - - - DUF1367 k59_319332_2 1540095.A0A0A0YP73_9CAUD 2.06e-14 73.6 4QAVB@10239|Viruses,4QPIJ@28883|Caudovirales,4QI48@10662|Myoviridae 10662|Myoviridae S defense response to bacterium - - - - - - - - - - - - - k59_51733_1 240016.ABIZ01000001_gene5053 6.56e-07 58.5 2DR7Z@1|root,33AM6@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_355515_5 324925.Ppha_1670 1.74e-14 75.5 COG0847@1|root,COG0847@2|Bacteria 2|Bacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - 2.7.7.7,3.6.4.12 ko:K02337,ko:K02342,ko:K03654 ko00230,ko00240,ko01100,ko03018,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03018,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DEAD,Helicase_C,Helicase_C_2,RNase_T,RecQ_Zn_bind k59_100410_3 105154.Q9MBU6_9VIRU 1.7e-174 511.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_76028_2 1410624.JNKK01000045_gene546 8.24e-07 56.6 COG1511@1|root,COG4675@1|root,COG1511@2|Bacteria,COG4675@2|Bacteria,1V943@1239|Firmicutes,24PFY@186801|Clostridia 186801|Clostridia S PFAM Tail Collar domain protein - - - - - - - - - - - - Collar k59_14503_2 1986029.Q9MBM3_9VIRU 4.86e-63 207.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_14503_4 1609634.A0A0C5AFV4_9VIRU 8.49e-254 711.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_14503_5 1609634.A0A0C5ANA6_9VIRU 1.04e-17 86.7 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_258990_1 857293.CAAU_0718 3.02e-22 97.1 COG1573@1|root,COG1573@2|Bacteria,1V4M9@1239|Firmicutes,24C6M@186801|Clostridia,36E51@31979|Clostridiaceae 186801|Clostridia L uracil-DNA glycosylase - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_211046_2 1502724.FF80_03325 2.94e-14 72.0 COG0593@1|root,COG0593@2|Bacteria,1P7AH@1224|Proteobacteria,2UXII@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Bacterial dnaA protein helix-turn-helix - - - - - - - - - - - - Bac_DnaA_C k59_356375_2 1121877.JQKF01000007_gene976 5.48e-47 156.0 COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,4CN4R@84992|Acidimicrobiia 84992|Acidimicrobiia L Single-strand binding protein family ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_52619_1 691965.D4P7D6_9CAUD 3.96e-142 434.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_52619_4 1476888.X4Y7Z1_9CAUD 8.17e-63 207.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_52619_8 1537917.JU82_09980 1.54e-24 96.7 2ARVA@1|root,31H70@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - HK97-gp10_like k59_52619_9 411460.RUMTOR_01335 8.28e-65 224.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_65194_1 172088.AUGA01000017_gene2388 7.33e-17 82.0 COG0305@1|root,COG0305@2|Bacteria,1QT50@1224|Proteobacteria,2TTND@28211|Alphaproteobacteria,3JW9V@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L TOPRIM - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - AAA_25,DnaB_C,Toprim_2,Toprim_4 k59_125940_1 1609634.A0A0C5AFV4_9VIRU 3.09e-74 241.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_149915_1 1574422.A0A0A1ENW9_9CIRC 2.43e-62 206.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_234915_1 291603.REP7_FBNY1 4.91e-16 85.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_320373_1 1385658.U5KPZ6_9VIRU 7.11e-105 321.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_77017_2 470.IX87_01465 1.03e-08 59.3 29W53@1|root,30HQ1@2|Bacteria,1PZQ9@1224|Proteobacteria,1SPPX@1236|Gammaproteobacteria 1236|Gammaproteobacteria S HNH endonuclease - - - - - - - - - - - - HNH_3 k59_28499_2 1485544.JQKP01000011_gene745 1.66e-10 62.0 2E645@1|root,330T3@2|Bacteria,1NEGX@1224|Proteobacteria,2VY99@28216|Betaproteobacteria 28216|Betaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_368342_3 340177.Cag_1919 4.58e-05 56.6 COG2911@1|root,COG2931@1|root,COG3210@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria 2|Bacteria U domain, Protein - - 2.7.11.1 ko:K12567,ko:K20276 ko02024,ko05410,ko05414,map02024,map05410,map05414 - - - ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812 - - - Calx-beta,DUF4347,HemolysinCabind k59_356497_2 1788444.A0A190WHB9_9CIRC 4.83e-57 189.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_259138_2 1609634.A0A0C5AFV4_9VIRU 1.41e-35 135.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_90352_3 595460.RRSWK_03642 3.19e-29 131.0 2DME6@1|root,32QWJ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_235716_3 1121011.AUCB01000031_gene2179 1.39e-16 94.7 COG1361@1|root,COG2152@1|root,COG3204@1|root,COG1361@2|Bacteria,COG2152@2|Bacteria,COG3204@2|Bacteria 2|Bacteria L pilus organization - - - ko:K02674,ko:K07004 - - - - ko00000,ko02035,ko02044 - - - DUF11,LTD k59_235716_4 716544.wcw_0671 1.79e-77 251.0 COG4626@1|root,COG4626@2|Bacteria 2|Bacteria S Terminase - - - - - - - - - - - - Terminase_1 k59_235861_1 145579.CAPSD_BPPHM 3.57e-98 312.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_235861_4 145579.REP_BPPHM 7.94e-39 146.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_102577_3 1165094.RINTHH_3920 5.09e-74 237.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_102577_5 105154.Q9MBU6_9VIRU 3.42e-218 622.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_78161_2 1040987.AZUY01000003_gene3422 1.12e-09 55.5 COG3847@1|root,COG3847@2|Bacteria,1NGVU@1224|Proteobacteria,2UJE8@28211|Alphaproteobacteria,43ME8@69277|Phyllobacteriaceae 28211|Alphaproteobacteria U PFAM Flp Fap pilin component pilA - - ko:K02651 ko04112,map04112 - - - ko00000,ko00001,ko02035,ko02044 - - - Flp_Fap k59_260099_2 358220.C380_08845 2.61e-07 60.8 29KX8@1|root,307UQ@2|Bacteria,1RK1N@1224|Proteobacteria,2VXY6@28216|Betaproteobacteria,4AGT1@80864|Comamonadaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_381847_2 1618259.A0A0C5I2B5_9CIRC 3.66e-96 291.0 4QE84@10239|Viruses,4QUKR@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_260105_1 1121448.DGI_2054 7.73e-28 111.0 COG0740@1|root,COG0740@2|Bacteria,1MUQ9@1224|Proteobacteria,42TUH@68525|delta/epsilon subdivisions,2WQCB@28221|Deltaproteobacteria 28221|Deltaproteobacteria OU Serine dehydrogenase proteinase - - - - - - - - - - - - CLP_protease k59_345496_1 565045.NOR51B_489 6.95e-32 131.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1J4Z9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_53835_1 78398.KS43_10190 1.72e-07 53.9 28J67@1|root,2Z91Y@2|Bacteria,1R7RG@1224|Proteobacteria,1RZB8@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_357402_1 369723.Strop_0517 1.14e-53 177.0 2EES9@1|root,338JX@2|Bacteria,2H5MY@201174|Actinobacteria 201174|Actinobacteria L RNase_H superfamily - - - - - - - - - - - - RNase_H_2 k59_151074_1 686340.Metal_0641 4.17e-50 171.0 28MEU@1|root,2ZASF@2|Bacteria,1R7N3@1224|Proteobacteria,1RYFK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S TIGRFAM Phage recombination protein Bet - - - - - - - - - - - - RecT k59_333522_1 640132.Srot_2345 1.39e-35 130.0 2D5AF@1|root,32TIM@2|Bacteria,2IFIY@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - PDDEXK_1 k59_369357_1 335543.Sfum_1893 0.000243 50.8 COG3210@1|root,COG4723@1|root,COG4733@1|root,COG3210@2|Bacteria,COG4723@2|Bacteria,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,42QDD@68525|delta/epsilon subdivisions,2WIU9@28221|Deltaproteobacteria 28221|Deltaproteobacteria U Phage-related protein, tail - - - - - - - - - - - - Phage-tail_3 k59_369361_1 290397.Adeh_3824 0.000442 47.4 COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,42PPW@68525|delta/epsilon subdivisions,2WM1S@28221|Deltaproteobacteria,2YVFT@29|Myxococcales 28221|Deltaproteobacteria L Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - RadC k59_296968_2 369723.Strop_0517 1.43e-77 242.0 2EES9@1|root,338JX@2|Bacteria,2H5MY@201174|Actinobacteria 201174|Actinobacteria L RNase_H superfamily - - - - - - - - - - - - RNase_H_2 k59_127917_2 1120963.KB894501_gene316 2.67e-10 60.8 COG2852@1|root,COG2852@2|Bacteria,1N7EJ@1224|Proteobacteria,1SF5D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - DUF559 k59_127917_3 877418.ATWV01000003_gene583 3.39e-09 59.7 COG1573@1|root,COG1573@2|Bacteria,2J612@203691|Spirochaetes 203691|Spirochaetes L Uracil-DNA glycosylase, family 4 ung - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_152043_1 748280.NH8B_1629 0.000107 50.4 COG4547@1|root,COG4547@2|Bacteria,1MX11@1224|Proteobacteria,2VKXX@28216|Betaproteobacteria 28216|Betaproteobacteria H Cobalt chelatase, CobT subunit cobT - 6.6.1.2 ko:K09883 ko00860,ko01100,map00860,map01100 - R05227 RC02000 ko00000,ko00001,ko01000 - - - CobT,CobT_C k59_346341_1 1536770.R50345_05915 0.000129 50.1 COG2188@1|root,COG2188@2|Bacteria,1UIRR@1239|Firmicutes,4ITSU@91061|Bacilli 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - GntR k59_139790_4 469616.FMAG_01788 9.56e-22 102.0 COG5377@1|root,COG5377@2|Bacteria,37BW3@32066|Fusobacteria 32066|Fusobacteria L YqaJ-like viral recombinase domain - - - - - - - - - - - - YqaJ k59_42461_1 1273711.A0A096VKF5_9CAUD 4.14e-41 160.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales,4QNDH@10744|Podoviridae 10744|Podoviridae S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_260793_3 1234888.K0A2J2_9VIRU 5.77e-111 343.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_139798_1 1385658.U5KPZ6_9VIRU 1.32e-66 219.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_103455_1 1235457.C404_28850 3.31e-70 224.0 COG0827@1|root,COG0827@2|Bacteria,1MUZW@1224|Proteobacteria,2VN3F@28216|Betaproteobacteria,1K4PN@119060|Burkholderiaceae 28216|Betaproteobacteria L Domain of unknown function (DUF4942) - - - - - - - - - - - - DUF4942 k59_67113_1 1454004.AW11_02382 1.04e-22 99.4 COG1074@1|root,COG1074@2|Bacteria,1QUUZ@1224|Proteobacteria,2WI1S@28216|Betaproteobacteria 28216|Betaproteobacteria L PDDEXK-like domain of unknown function (DUF3799) - - - - - - - - - - - - DUF3799 k59_91669_5 1609634.A0A0C5AFT2_9VIRU 2.46e-150 432.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_91669_7 1609634.A0A0C5AFV4_9VIRU 1.41e-170 494.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_273618_3 658655.HMPREF0988_02585 5.56e-19 88.6 COG0629@1|root,COG0629@2|Bacteria,1UI1P@1239|Firmicutes,24MGJ@186801|Clostridia 186801|Clostridia L ERF superfamily - - - - - - - - - - - - ERF k59_139984_1 1385658.U5KPZ6_9VIRU 4.39e-81 263.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_128875_2 1609634.A0A0C5AFV4_9VIRU 2.07e-79 260.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_359072_2 645512.GCWU000246_01672 1.45e-05 52.0 2C4QM@1|root,32REC@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF4355,Phage_GP20 k59_299119_1 1178537.BA1_16711 3.09e-18 84.3 COG3941@1|root,COG3953@1|root,COG5280@1|root,COG3941@2|Bacteria,COG3953@2|Bacteria,COG5280@2|Bacteria,1VAT4@1239|Firmicutes,4HMYI@91061|Bacilli,1ZFFP@1386|Bacillus 91061|Bacilli L Transglycosylase SLT domain xkdO - - - - - - - - - - - SLT k59_31634_1 105154.Q9MBU3_9VIRU 5.17e-10 61.6 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_31635_3 626887.J057_01785 6.42e-19 89.7 2DCM2@1|root,32TZV@2|Bacteria,1NAGE@1224|Proteobacteria,1SMRS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_214396_3 1280952.HJA_12805 1.74e-05 56.2 COG0739@1|root,COG4219@1|root,COG0739@2|Bacteria,COG4219@2|Bacteria,1R8E7@1224|Proteobacteria,2TYFZ@28211|Alphaproteobacteria,43Y69@69657|Hyphomonadaceae 28211|Alphaproteobacteria KMT BlaR1 peptidase M56 - - - - - - - - - - - - Peptidase_M23,Peptidase_M56,TonB_C k59_214396_4 909297.G8CLB0_9CAUD 3.46e-08 58.5 4QGI6@10239|Viruses,4QTVZ@28883|Caudovirales,4QM84@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_214396_7 691965.D4P7C5_9CAUD 0.0 994.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_323427_1 1115515.EV102420_11_00070 1.37e-18 89.0 COG2911@1|root,COG5281@1|root,COG2911@2|Bacteria,COG5281@2|Bacteria 2|Bacteria D sister chromatid segregation - - - - - - - - - - - - Phage_HK97_TLTM,SLT,Tape_meas_lam_C k59_323427_2 443152.MDG893_20574 3.02e-30 112.0 2CHRA@1|root,32S6D@2|Bacteria,1MZ8I@1224|Proteobacteria,1SHSQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage tail assembly chaperone, TAC - - - - - - - - - - - - Phage_TAC_13 k59_383362_1 638303.Thal_1246 7.96e-10 65.5 COG0749@1|root,COG0749@2|Bacteria,2G4NU@200783|Aquificae 200783|Aquificae L DNA polymerase polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_pol_A,DNA_pol_A_exo1 k59_226560_1 312309.VF_0074 8.24e-06 54.7 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1XUAZ@135623|Vibrionales 135623|Vibrionales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_55782_1 1609634.A0A0C5AFV4_9VIRU 3.31e-38 141.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_55782_3 1165094.RINTHH_3920 6.19e-88 272.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_214600_1 49964.Q94MS1_9CAUD 1.06e-48 167.0 4QB4H@10239|Viruses,4QYQI@35237|dsDNA viruses no RNA stage,4QUAR@28883|Caudovirales,4QNUV@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_201652_5 382640.BT_0980 3.86e-28 112.0 2DQEE@1|root,336AX@2|Bacteria,1MY8N@1224|Proteobacteria,2UI1U@28211|Alphaproteobacteria,48SYK@772|Bartonellaceae 28211|Alphaproteobacteria L Exonuclease (EC 3.1.11.3) (P03697 of bacteriophage lambda) - - 3.1.11.3 ko:K01143 - - - - ko00000,ko01000 - - - YqaJ k59_92994_1 1123072.AUDH01000007_gene1234 2.11e-36 144.0 COG0741@1|root,COG3409@1|root,COG0741@2|Bacteria,COG3409@2|Bacteria 2|Bacteria M Peptidoglycan-binding domain 1 protein exeA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 - ko:K02450,ko:K03194,ko:K08309 ko03070,map03070 M00331,M00333 - - ko00000,ko00001,ko00002,ko01000,ko01011,ko02044 9.B.42 GH23 - AAA_22,PG_binding_1,SLT k59_92994_3 1279017.AQYJ01000026_gene5 6.81e-13 69.7 2AD08@1|root,312N7@2|Bacteria,1NDC4@1224|Proteobacteria,1SAPT@1236|Gammaproteobacteria,467W0@72275|Alteromonadaceae 1236|Gammaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_18172_1 264732.Moth_0752 3.45e-29 118.0 COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,42FQR@68295|Thermoanaerobacterales 186801|Clostridia E Belongs to the DegT DnrJ EryC1 family spsC - 2.6.1.102 ko:K13010 ko00520,map00520 - R10460 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 - - - DegT_DnrJ_EryC1 k59_275144_1 1232410.KI421417_gene2767 8.68e-19 89.0 29UKS@1|root,30FY7@2|Bacteria,1RGKW@1224|Proteobacteria,430C2@68525|delta/epsilon subdivisions,2WW6K@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_202328_1 1692249.A0A0K1RLN8_9CIRC 1.74e-20 91.7 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_348531_3 439375.Oant_0213 2.02e-31 129.0 COG0468@1|root,COG0468@2|Bacteria,1PK58@1224|Proteobacteria,2UB77@28211|Alphaproteobacteria 28211|Alphaproteobacteria L AAA domain - - - - - - - - - - - - AAA_24 k59_215533_3 626887.J057_01685 1.54e-78 246.0 28HS3@1|root,2Z7ZE@2|Bacteria,1QH9A@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_238669_1 1122201.AUAZ01000021_gene3147 4.61e-32 125.0 COG1783@1|root,COG1783@2|Bacteria 2|Bacteria S DNA packaging - - - ko:K06909 - - - - ko00000 - - - Terminase_3 k59_238669_2 69279.BG36_20870 1.22e-59 203.0 COG3170@1|root,COG3170@2|Bacteria,1QVEE@1224|Proteobacteria,2TWDG@28211|Alphaproteobacteria 28211|Alphaproteobacteria NU Phage P22-like portal protein - - - - - - - - - - - - P22_portal k59_348536_1 1246459.KB898368_gene2682 2.09e-51 171.0 COG1442@1|root,COG1442@2|Bacteria,1QH4S@1224|Proteobacteria,2U9KQ@28211|Alphaproteobacteria,4B9U9@82115|Rhizobiaceae 28211|Alphaproteobacteria M glycosyl transferase family 8 - - - - - - - - - - - - - k59_275373_2 886293.Sinac_3413 2.13e-27 112.0 COG1216@1|root,COG1216@2|Bacteria 2|Bacteria V Glycosyl transferase, family 2 - - - - - - - - - - - - Glycos_transf_2 k59_275373_3 760192.Halhy_0673 1.34e-28 112.0 COG4122@1|root,COG4122@2|Bacteria 2|Bacteria E O-methyltransferase activity - - - - - - - - - - - - Glycos_transf_2,Methyltransf_24 k59_289427_3 691965.D4P7I3_9CAUD 1.68e-76 261.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_263486_1 1035191.HMPREF0185_03554 4.49e-50 175.0 28IN7@1|root,2Z8NM@2|Bacteria,1NRFQ@1224|Proteobacteria 1224|Proteobacteria S Capsid protein (F protein) - - - - - - - - - - - - Phage_F k59_81745_1 665956.HMPREF1032_00688 5.36e-49 169.0 28K55@1|root,2Z9TX@2|Bacteria,1V0P7@1239|Firmicutes,24DCX@186801|Clostridia,3WK99@541000|Ruminococcaceae 186801|Clostridia S Psort location Cytoplasmic, score 7.50 - - - - - - - - - - - - Sipho_Gp37 k59_81745_2 665956.HMPREF1032_00687 9.24e-77 243.0 2E2JP@1|root,32XP4@2|Bacteria,1VAIM@1239|Firmicutes,24PPR@186801|Clostridia,3WI4W@541000|Ruminococcaceae 186801|Clostridia S Phage tail protein - - - - - - - - - - - - Sipho_tail k59_81745_3 742733.HMPREF9469_05020 1.07e-236 753.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,221IX@1506553|Lachnoclostridium 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_290039_1 1692249.A0A0K1RL40_9CIRC 5.47e-106 315.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_312559_3 654925.Q4A2Q2_EHV8U 1.37e-16 77.0 4QB0E@10239|Viruses,4QXJE@35237|dsDNA viruses no RNA stage 10239|Viruses S Pyrimidine dimer DNA glycosylase - GO:0000704,GO:0003674,GO:0003824,GO:0003906,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0140097 - - - - - - - - - - - k59_373062_2 1029823.AFIE01000007_gene1906 0.000158 46.6 2EMSQ@1|root,33FF4@2|Bacteria,1NDKJ@1224|Proteobacteria,1SDC7@1236|Gammaproteobacteria,3NNBI@468|Moraxellaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1064) - - - - - - - - - - - - DUF1064 k59_8803_1 1692255.A0A0K1RL52_9CIRC 1.34e-105 317.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_166695_5 563192.HMPREF0179_03420 2.07e-23 94.4 2EHVE@1|root,32QS6@2|Bacteria,1P3YB@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_166695_12 1496688.ER33_05835 5.12e-27 122.0 COG0553@1|root,COG0553@2|Bacteria,1GHHG@1117|Cyanobacteria,22RNR@167375|Cyanobium 1117|Cyanobacteria F SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_166695_16 904144.AEJD01000006_gene541 7.97e-27 117.0 COG2887@1|root,COG2887@2|Bacteria,2IBBB@201174|Actinobacteria 201174|Actinobacteria L Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_166695_18 348824.LPU83_1746 1.72e-95 315.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,2UNT9@28211|Alphaproteobacteria,4BJFM@82115|Rhizobiaceae 28211|Alphaproteobacteria L COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_228224_3 1385658.U5KPZ6_9VIRU 7.33e-100 308.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_312761_2 1035196.HMPREF9998_01832 4.96e-09 62.4 COG1357@1|root,COG1357@2|Bacteria,1V3RU@1239|Firmicutes,24F0J@186801|Clostridia,25TKN@186804|Peptostreptococcaceae 186801|Clostridia S Pentapeptide repeat protein - - - - - - - - - - - - Pentapeptide k59_8806_1 1211777.BN77_4181 4.18e-23 102.0 COG4675@1|root,COG4675@2|Bacteria,1QWQH@1224|Proteobacteria,2UUR5@28211|Alphaproteobacteria,4BFMU@82115|Rhizobiaceae 28211|Alphaproteobacteria S tail collar domain protein - - - - - - - - - - - - Collar k59_385004_1 1609634.A0A0C5AFV4_9VIRU 1.67e-55 190.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_228226_1 1385658.U5KPZ6_9VIRU 1.11e-64 215.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_373069_1 348824.LPU83_1717 1.1e-18 85.1 28PTM@1|root,2ZCEU@2|Bacteria,1R5DD@1224|Proteobacteria,2TVG7@28211|Alphaproteobacteria,4BGD7@82115|Rhizobiaceae 28211|Alphaproteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_373069_2 398578.Daci_1945 3.11e-18 86.7 2DTUK@1|root,33MQ2@2|Bacteria,1NPI3@1224|Proteobacteria,2W420@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_349601_4 880073.Calab_1470 4.24e-59 192.0 COG0270@1|root,COG0270@2|Bacteria 2|Bacteria L DNA (cytosine-5-)-methyltransferase activity dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_349601_7 1192868.CAIU01000008_gene937 4.3e-79 251.0 COG0863@1|root,COG0863@2|Bacteria,1NQ2A@1224|Proteobacteria,2UJ12@28211|Alphaproteobacteria,43KMC@69277|Phyllobacteriaceae 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase k59_349601_8 1537917.JU82_00020 4e-72 232.0 COG0553@1|root,COG0553@2|Bacteria,1PM15@1224|Proteobacteria,42ZGS@68525|delta/epsilon subdivisions,2YS8B@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria L DEAD-like helicases superfamily - - - - - - - - - - - - - k59_349601_10 742767.HMPREF9456_03390 8.17e-103 308.0 COG0175@1|root,COG0175@2|Bacteria,4PNYM@976|Bacteroidetes,2G11I@200643|Bacteroidia,230XX@171551|Porphyromonadaceae 2|Bacteria EH Phosphoadenosine phosphosulfate reductase family - - - - - - - - - - - - PAPS_reduct k59_290511_3 1795992.A0A140CTS6_9CIRC 1.9e-50 169.0 4QB6C@10239|Viruses,4QUKM@29258|ssDNA viruses 10239|Viruses J Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_290511_4 1862825.A0A193CE78_9VIRU 2.65e-26 106.0 4QAZA@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_216882_2 7739.XP_002597967.1 6.49e-06 52.4 KOG0613@1|root,KOG4221@1|root,KOG0613@2759|Eukaryota,KOG4221@2759|Eukaryota,38BAS@33154|Opisthokonta,3B9IR@33208|Metazoa,3CRJW@33213|Bilateria,484DC@7711|Chordata 33208|Metazoa T Titin-like unc-22 GO:0000070,GO:0000228,GO:0000278,GO:0000280,GO:0000768,GO:0000793,GO:0000794,GO:0000819,GO:0002682,GO:0003008,GO:0003012,GO:0003674,GO:0003779,GO:0003824,GO:0004672,GO:0004674,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005856,GO:0005859,GO:0005863,GO:0006323,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006936,GO:0006937,GO:0006941,GO:0006942,GO:0006949,GO:0006996,GO:0007010,GO:0007015,GO:0007049,GO:0007059,GO:0007062,GO:0007076,GO:0007275,GO:0007498,GO:0007517,GO:0007519,GO:0007520,GO:0007522,GO:0007525,GO:0007610,GO:0007626,GO:0008092,GO:0008150,GO:0008152,GO:0008307,GO:0008344,GO:0009636,GO:0009653,GO:0009888,GO:0009987,GO:0010638,GO:0010720,GO:0010927,GO:0014706,GO:0014902,GO:0015629,GO:0016043,GO:0016203,GO:0016301,GO:0016310,GO:0016459,GO:0016460,GO:0016740,GO:0016772,GO:0016773,GO:0018105,GO:0018107,GO:0018193,GO:0018209,GO:0018210,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0022402,GO:0022603,GO:0022607,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030154,GO:0030239,GO:0030261,GO:0030534,GO:0031032,GO:0031033,GO:0031034,GO:0031430,GO:0031672,GO:0031674,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032956,GO:0032970,GO:0032982,GO:0032989,GO:0032991,GO:0033043,GO:0034622,GO:0035094,GO:0035095,GO:0035206,GO:0036211,GO:0036379,GO:0040011,GO:0040012,GO:0040017,GO:0042127,GO:0042221,GO:0042493,GO:0042692,GO:0042805,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043412,GO:0043933,GO:0044057,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044877,GO:0045214,GO:0045595,GO:0045597,GO:0045933,GO:0045989,GO:0048285,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048646,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051015,GO:0051094,GO:0051128,GO:0051130,GO:0051146,GO:0051147,GO:0051149,GO:0051153,GO:0051155,GO:0051239,GO:0051240,GO:0051276,GO:0051302,GO:0051371,GO:0051393,GO:0051493,GO:0051495,GO:0051782,GO:0055001,GO:0055002,GO:0060284,GO:0060297,GO:0060298,GO:0060537,GO:0060538,GO:0061061,GO:0065003,GO:0065007,GO:0070013,GO:0070925,GO:0071103,GO:0071688,GO:0071689,GO:0071704,GO:0071840,GO:0090257,GO:0097435,GO:0097493,GO:0098813,GO:0099080,GO:0099081,GO:0099512,GO:0110020,GO:0140014,GO:0140096,GO:1901564,GO:1902115,GO:1902117,GO:1902903,GO:1902905,GO:1903047 2.7.11.1 ko:K12567 ko05410,ko05414,map05410,map05414 - - - ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812 - - - DUF1136,I-set,Ig_3,Pkinase,fn3 k59_301701_1 240016.ABIZ01000001_gene1613 3.6e-27 112.0 COG0270@1|root,COG0270@2|Bacteria 2|Bacteria L DNA (cytosine-5-)-methyltransferase activity dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_118230_2 1986029.Q9MBM8_9VIRU 2.85e-25 104.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_385358_1 1968.JOEV01000056_gene4918 3.94e-45 165.0 2EYX9@1|root,33S42@2|Bacteria,2IABS@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - Phage_capsid k59_106383_1 1121895.Q765_15005 1.54e-05 52.4 2EAST@1|root,334US@2|Bacteria,4NRGD@976|Bacteroidetes,1I583@117743|Flavobacteriia,2NU1I@237|Flavobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - k59_301708_1 444875.E3SMF7_9CAUD 1.2e-05 55.8 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNBD@10744|Podoviridae 10744|Podoviridae S outer membrane - - - - - - - - - - - - - k59_228732_2 4787.PITG_03943T0 3.55e-14 76.3 COG0500@1|root,2S9CR@2759|Eukaryota,3Q9G1@4776|Peronosporales 4776|Peronosporales Q Mycolic acid cyclopropane synthetase - - - - - - - - - - - - Methyltransf_25 k59_143126_6 1133293.H2EIC1_9CAUD 1.01e-24 112.0 4QAUC@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_188549_1 742767.HMPREF9456_03337 9.49e-18 85.9 COG5410@1|root,COG5410@2|Bacteria,4NN30@976|Bacteroidetes,2FM53@200643|Bacteroidia,230ZQ@171551|Porphyromonadaceae 976|Bacteroidetes S domain protein - - - - - - - - - - - - - k59_95312_1 596154.Alide2_4807 5.79e-08 59.7 COG1475@1|root,COG1475@2|Bacteria,1N87M@1224|Proteobacteria 1224|Proteobacteria K ParB-like nuclease domain - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_82440_1 1187851.A33M_1701 8.57e-39 147.0 COG1345@1|root,COG1511@1|root,COG1345@2|Bacteria,COG1511@2|Bacteria,1QW8I@1224|Proteobacteria,2TU4X@28211|Alphaproteobacteria 28211|Alphaproteobacteria N Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end - - - - - - - - - - - - TMP_2 k59_338436_3 1089550.ATTH01000001_gene1848 1.91e-16 80.5 COG0175@1|root,COG0175@2|Bacteria,4NE9H@976|Bacteroidetes 976|Bacteroidetes EH Phosphoadenosine phosphosulfate reductase - - - - - - - - - - - - PAPS_reduct k59_188965_1 158500.BV97_03964 2.63e-82 260.0 COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,2K2BG@204457|Sphingomonadales 204457|Sphingomonadales S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_264571_2 1788447.A0A190WHJ9_9CIRC 1.66e-101 305.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_326455_1 1609634.A0A0C5AFV4_9VIRU 2.62e-35 137.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_302387_1 1121324.CLIT_13c01770 5.84e-05 48.1 COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,25R2J@186804|Peptostreptococcaceae 186801|Clostridia L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC - - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N k59_385976_1 314345.SPV1_02692 4.21e-33 137.0 COG5164@1|root,COG5164@2|Bacteria,1N2ZN@1224|Proteobacteria 1224|Proteobacteria K regulation of DNA-templated transcription, elongation - - - - - - - - - - - - Collagen k59_96049_1 105154.Q9MBU3_9VIRU 1.18e-07 57.4 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_264580_1 1192759.AKIB01000023_gene2907 5.6e-36 141.0 COG0553@1|root,COG0827@1|root,COG3087@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG3087@2|Bacteria,COG4646@2|Bacteria,1PGZG@1224|Proteobacteria,2TVEU@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DEAD-like helicases superfamily - - - - - - - - - - - - Helicase_C,N6_Mtase,ResIII,SNF2_N k59_229422_2 645512.GCWU000246_00697 1.54e-13 80.5 COG4653@1|root,COG4653@2|Bacteria,3TC5W@508458|Synergistetes 508458|Synergistetes S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_118975_2 717605.Theco_3974 6.28e-11 62.0 2E6SZ@1|root,331CZ@2|Bacteria,1VXJJ@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - k59_34894_1 205914.HS_1373 3.83e-20 94.4 2EXSU@1|root,33R23@2|Bacteria,1NS77@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_327123_1 585506.HMPREF0877_1284 1.34e-11 66.2 COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,4HARA@91061|Bacilli,4AX2W@81850|Leuconostocaceae 91061|Bacilli D Belongs to the 'phage' integrase family. XerC subfamily xerC - - ko:K03733,ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k59_374664_1 1304275.C41B8_05453 1.9e-53 192.0 COG0234@1|root,COG0234@2|Bacteria,1NJKP@1224|Proteobacteria 1224|Proteobacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter - - - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - - k59_314462_1 497965.Cyan7822_1900 3.6e-25 113.0 COG1028@1|root,COG2931@1|root,COG1028@2|Bacteria,COG2931@2|Bacteria,1G2IN@1117|Cyanobacteria,3KHMU@43988|Cyanothece 1117|Cyanobacteria IQ oxidoreductase activity - - - - - - - - - - - - - k59_265150_1 278957.ABEA03000161_gene118 9.66e-19 90.5 COG0553@1|root,COG0553@2|Bacteria 2|Bacteria L helicase activity - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_132611_4 869724.H6BI57_9CAUD 6.63e-42 157.0 4QBYN@10239|Viruses,4QZT8@35237|dsDNA viruses no RNA stage,4QR5G@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_157047_1 641147.HMPREF9021_02661 1.94e-06 49.3 2FJUN@1|root,34BH6@2|Bacteria,1P0ZB@1224|Proteobacteria,2W4E0@28216|Betaproteobacteria,2KT8M@206351|Neisseriales 206351|Neisseriales S Protein of unknown function (DUF2523) - - - - - - - - - - - - DUF2523 k59_181420_2 1609634.A0A0C5AFV4_9VIRU 7.35e-100 306.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_351087_1 428125.CLOLEP_01417 1.42e-46 156.0 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia,3WMXK@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_387151_1 698758.AXY_23850 5.47e-29 120.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli 91061|Bacilli L Participates in initiation and elongation during chromosome replication dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_315005_1 1692255.A0A0K1RL52_9CIRC 2.74e-40 141.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_315005_2 1692257.A0A0K1RL48_9CIRC 3.74e-38 145.0 4QCY8@10239|Viruses,4QUMD@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_303465_2 182217.HCW_02255 3.08e-15 80.1 COG0863@1|root,COG1092@1|root,COG0863@2|Bacteria,COG1092@2|Bacteria,1NXST@1224|Proteobacteria,42Q3Q@68525|delta/epsilon subdivisions,2YN8U@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_22013_2 89187.ISM_12830 0.000114 48.1 2DS89@1|root,33EYT@2|Bacteria,1NGG2@1224|Proteobacteria,2UKCA@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_303466_1 2003327.CAPSD_BPCHP 4.37e-30 123.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_351531_1 78245.Xaut_4480 0.000307 49.7 COG4675@1|root,COG4675@2|Bacteria,1PE25@1224|Proteobacteria,2V8UM@28211|Alphaproteobacteria,3F1UP@335928|Xanthobacteraceae 28211|Alphaproteobacteria S tail collar domain protein - - - - - - - - - - - - - k59_265692_1 1330700.JQNC01000003_gene486 6.45e-19 91.7 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1WIA1@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,Taq-exonuc k59_47679_1 749222.Nitsa_1823 1.16e-27 110.0 COG0270@1|root,COG0270@2|Bacteria,1N0XD@1224|Proteobacteria 1224|Proteobacteria H C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_84461_1 1197951.I6R0Z3_9CAUD 2.82e-25 106.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales 28883|Caudovirales S Ribonucleotide reductase, barrel domain - GO:0003674,GO:0003824,GO:0004748,GO:0008150,GO:0008152,GO:0016491,GO:0016725,GO:0016728,GO:0055114,GO:0061731 - - - - - - - - - - - k59_315181_1 1609634.A0A0C5AFV4_9VIRU 1.27e-81 270.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_315181_6 105154.Q9MBU0_9VIRU 8.63e-27 114.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_315181_7 1234888.K0A2J2_9VIRU 1.74e-06 49.3 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_157661_1 556268.OFAG_00940 3.04e-26 117.0 2CENN@1|root,32VYV@2|Bacteria,1N4RC@1224|Proteobacteria,2W1J6@28216|Betaproteobacteria,476WV@75682|Oxalobacteraceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_120187_4 1410619.SRDD_15740 1.25e-05 48.9 COG0863@1|root,COG0863@2|Bacteria,1R7KV@1224|Proteobacteria,1RZ25@1236|Gammaproteobacteria,4048F@613|Serratia 1236|Gammaproteobacteria L DNA methylase VP0394 - 2.1.1.72 ko:K00571,ko:K07319 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_254302_1 1002339.HMPREF9373_2624 2.67e-146 428.0 COG0507@1|root,COG0507@2|Bacteria,1MUTR@1224|Proteobacteria,1RQS3@1236|Gammaproteobacteria,3NJSK@468|Moraxellaceae 1236|Gammaproteobacteria L MobA/MobL family - - - - - - - - - - - - MobA_MobL k59_254302_4 1055815.AYYA01000027_gene573 1.21e-92 271.0 COG0789@1|root,COG0789@2|Bacteria,1NMFG@1224|Proteobacteria,1SZ25@1236|Gammaproteobacteria,3NNN9@468|Moraxellaceae 1236|Gammaproteobacteria K helix_turn_helix, mercury resistance - - - - - - - - - - - - - k59_254302_5 1217710.F969_01524 1.4e-74 224.0 COG5527@1|root,COG5527@2|Bacteria,1P7B0@1224|Proteobacteria,1SW9Q@1236|Gammaproteobacteria,3NSJA@468|Moraxellaceae 1236|Gammaproteobacteria L Initiator Replication protein - - - - - - - - - - - - - k59_278472_1 1000565.METUNv1_01765 1.84e-05 46.2 2CPPK@1|root,32SJJ@2|Bacteria,1MZQ2@1224|Proteobacteria,2VU8G@28216|Betaproteobacteria,2KZ8N@206389|Rhodocyclales 206389|Rhodocyclales S Protein of unknown function (DUF2786) - - - - - - - - - - - - DUF2786 k59_278472_2 1415778.JQMM01000001_gene131 1.8e-12 69.3 COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,1J5Z0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K Response regulator of the LytR AlgR family algR - - ko:K08083 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg k59_205935_7 762903.Pedsa_3094 2.18e-17 76.6 2C8RN@1|root,32RMQ@2|Bacteria,4NSD0@976|Bacteroidetes,1IUGX@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_108959_1 935261.JAGL01000009_gene1160 4.25e-16 82.4 2DUXE@1|root,32UY2@2|Bacteria,1N2YI@1224|Proteobacteria,2UEWK@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage T7 capsid assembly protein - - - - - - - - - - - - Phage_T7_Capsid k59_72805_3 398578.Daci_1946 7.02e-08 60.1 28PTM@1|root,2ZCEU@2|Bacteria,1R5DD@1224|Proteobacteria,2W259@28216|Betaproteobacteria 28216|Betaproteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_11385_2 1609634.A0A0C5ANA6_9VIRU 3.87e-11 67.8 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_169424_7 471852.Tcur_2031 3.46e-14 73.9 arCOG05626@1|root,30CNA@2|Bacteria,2I38B@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_169424_10 742733.HMPREF9469_05062 5.97e-124 367.0 COG0553@1|root,COG0553@2|Bacteria,1TS9W@1239|Firmicutes,24CGX@186801|Clostridia,222GT@1506553|Lachnoclostridium 186801|Clostridia KL Helicase conserved C-terminal domain - - - - - - - - - - - - - k59_72807_1 548477.HMPREF0294_2290 1.66e-33 129.0 COG0562@1|root,COG0562@2|Bacteria,2GK2Z@201174|Actinobacteria,22JKH@1653|Corynebacteriaceae 201174|Actinobacteria M UDP-galactopyranose mutase glf GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008767,GO:0009273,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0030312,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071840,GO:0071944 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 - R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 - - iNJ661.Rv3809c GLF,NAD_binding_8 k59_363413_1 243233.MCA2930 1.28e-45 166.0 COG5301@1|root,COG5301@2|Bacteria,1NDIE@1224|Proteobacteria,1SFIF@1236|Gammaproteobacteria 1236|Gammaproteobacteria G cellulose 1,4-beta-cellobiosidase activity - - - - - - - - - - - - - k59_278712_3 1385658.U5KPZ6_9VIRU 2.03e-144 433.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_376292_1 1123239.KB898628_gene3227 2.27e-14 75.9 2DR9Y@1|root,33AUY@2|Bacteria,1VEP1@1239|Firmicutes,4HP3X@91061|Bacilli 91061|Bacilli L NUMOD4 motif - - - - - - - - - - - - HNH_3,NUMOD4 k59_266489_3 395492.Rleg2_2466 5.79e-25 97.8 2CJKM@1|root,314EI@2|Bacteria,1RGVN@1224|Proteobacteria,2UBK7@28211|Alphaproteobacteria,4BJCA@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_206263_1 1519439.JPJG01000060_gene1885 3.64e-16 84.3 COG1783@1|root,COG4373@1|root,COG1783@2|Bacteria,COG4373@2|Bacteria,1TU2Y@1239|Firmicutes,25MM3@186801|Clostridia,2N7J6@216572|Oscillospiraceae 186801|Clostridia S phage Terminase large subunit - - - - - - - - - - - - Terminase_3 k59_352267_1 1449063.JMLS01000030_gene460 1.18e-11 70.1 COG5280@1|root,COG5412@1|root,COG5280@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HGP4@91061|Bacilli,26UKE@186822|Paenibacillaceae 91061|Bacilli E minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_48554_2 420324.KI912045_gene4340 3.3e-37 129.0 2DTKS@1|root,33KSY@2|Bacteria,1NN6H@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_22843_1 10756.PORTL_BPPH2 2.02e-14 75.5 4QDW3@10239|Viruses 10239|Viruses S Phage Connector (GP10) - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046729,GO:0046798,GO:0051704 - - - - - - - - - - - k59_278967_1 1123508.JH636451_gene6021 5.99e-21 97.1 COG3864@1|root,COG3864@2|Bacteria 2|Bacteria S Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N k59_206266_2 1618248.A0A0C5IB82_9CIRC 1.37e-80 253.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388277_2 1116472.MGMO_205c00050 5.39e-43 146.0 28HVF@1|root,2Z81Q@2|Bacteria,1NZPF@1224|Proteobacteria,1SRZ6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacteriophage scaffolding protein D - - - - - - - - - - - - gpD k59_388277_8 1116472.MGMO_205c00030 7.36e-105 324.0 28IN7@1|root,2Z8NM@2|Bacteria,1NRFQ@1224|Proteobacteria,1SKG7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Capsid protein (F protein) - - - - - - - - - - - - Phage_F k59_364022_3 41875.XP_007508395.1 0.000129 50.1 2CPSB@1|root,2R2IX@2759|Eukaryota,383XZ@33090|Viridiplantae,34JEE@3041|Chlorophyta 3041|Chlorophyta S Methionine biosynthesis protein MetW - - - - - - - - - - - - Methyltransf_11 k59_364022_4 96561.Dole_1632 2.93e-05 51.2 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,42M8S@68525|delta/epsilon subdivisions,2WNG8@28221|Deltaproteobacteria,2MIMS@213118|Desulfobacterales 28221|Deltaproteobacteria K Belongs to the ParB family parB - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_170005_2 1609634.A0A0C5AFV4_9VIRU 1.29e-122 370.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_12029_1 1232410.KI421421_gene3745 4.86e-07 56.6 COG4653@1|root,COG4653@2|Bacteria,1MWMB@1224|Proteobacteria,42UPY@68525|delta/epsilon subdivisions,2WQZZ@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_364025_1 1574422.A0A0A1ENW9_9CIRC 3.38e-53 181.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_206552_2 679189.HMPREF9019_0655 7.11e-07 58.9 COG2189@1|root,COG2189@2|Bacteria,4NHTG@976|Bacteroidetes,2FQKU@200643|Bacteroidia 976|Bacteroidetes L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571,ko:K07319 - - - - ko00000,ko01000,ko02048 - - - MerR,N6_N4_Mtase k59_23152_1 1788443.A0A190WHA2_9CIRC 5.31e-11 67.8 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_190780_1 1197951.I6S2A3_9CAUD 1.46e-40 145.0 4QAIV@10239|Viruses,4QYFZ@35237|dsDNA viruses no RNA stage,4QQUY@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_364031_1 1158150.KB906242_gene227 1.97e-79 266.0 28IA2@1|root,2Z8CQ@2|Bacteria,1PQM2@1224|Proteobacteria,1SN3W@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_388278_1 1385658.U5KPZ6_9VIRU 1.34e-65 217.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_388278_8 1385658.U5KPZ6_9VIRU 2.79e-139 414.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_364036_2 1472912.A0A023NGT1_9CAUD 1.47e-34 134.0 4QAW1@10239|Viruses,4QWUW@35237|dsDNA viruses no RNA stage,4QR8A@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_267103_1 290402.Cbei_4758 1.83e-29 117.0 COG1216@1|root,COG1216@2|Bacteria,1UYRR@1239|Firmicutes,249T1@186801|Clostridia,36HGQ@31979|Clostridiaceae 186801|Clostridia M PFAM Glycosyl transferase family 2 - - - ko:K07011,ko:K20444 - - - - ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 - Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2,Methyltransf_23 k59_388344_2 1379715.S5TMW6_9CIRC 2.15e-36 138.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_191278_3 948071.S4S2F7_9CAUD 4.07e-13 76.3 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_191281_1 1234888.K0A2J2_9VIRU 5.27e-63 211.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_23836_1 1692255.A0A0K1RL52_9CIRC 2.64e-34 127.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_23836_2 1618237.A0A0C5IMG6_9CIRC 9.9e-14 74.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_192235_2 105154.Q9MBU6_9VIRU 8.52e-180 522.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_192267_2 290633.GOX2457 5.74e-69 223.0 COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,2JWSP@204441|Rhodospirillales 204441|Rhodospirillales S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_388473_2 1379724.S5T6B0_9CIRC 4.53e-19 92.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388474_3 142661.REP_CACV 7.33e-41 154.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388476_1 1692244.A0A0K1RLR5_9CIRC 1.85e-40 149.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388480_1 650150.ERH_1292 9.64e-18 89.7 28MKK@1|root,2ZAWR@2|Bacteria,1UYAT@1239|Firmicutes,3VSD5@526524|Erysipelotrichia 526524|Erysipelotrichia S Putative viral replication protein - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_388490_2 1692253.A0A0K1RLM4_9CIRC 1.27e-33 132.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_192360_2 265072.Mfla_2707 3.58e-48 160.0 COG3023@1|root,COG3023@2|Bacteria,1RJ5G@1224|Proteobacteria,2VSE4@28216|Betaproteobacteria 28216|Betaproteobacteria V N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2 k59_303849_1 1414738.V5UQL8_9CAUD 1.32e-90 289.0 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_85201_1 617140.AJZE01000062_gene2963 6.58e-10 65.5 COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,1RPIG@1236|Gammaproteobacteria,1XSC4@135623|Vibrionales 135623|Vibrionales M NeuB family - - 2.5.1.56 ko:K01654 ko00520,ko01100,map00520,map01100 - R01804,R04435 RC00159 ko00000,ko00001,ko01000 - - - NeuB,SAF k59_158104_2 1618238.A0A0C5IB41_9CIRC 0.000278 50.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_352485_3 1618248.A0A0C5IB82_9CIRC 2.83e-55 188.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_109452_3 1379707.S5SXZ4_9CIRC 1.44e-10 65.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_230972_5 883.DvMF_1065 2.96e-09 67.0 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,42Z58@68525|delta/epsilon subdivisions,2WTW4@28221|Deltaproteobacteria,2M8HG@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_109453_1 439235.Dalk_4601 2.29e-18 82.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42TV9@68525|delta/epsilon subdivisions,2WNAN@28221|Deltaproteobacteria,2MKNW@213118|Desulfobacterales 28221|Deltaproteobacteria L Single-stranded DNA-binding protein ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_352486_1 1298858.AUEL01000029_gene80 2.76e-08 63.9 2C2IA@1|root,2ZW5P@2|Bacteria,1PB15@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_328177_2 1547445.LO80_03300 1.52e-13 72.4 COG1783@1|root,COG1783@2|Bacteria,1MWGP@1224|Proteobacteria,1S8D6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_218872_1 1379712.S5TMV9_9CIRC 4.37e-09 65.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_133766_2 1122963.AUHB01000029_gene4522 9.81e-19 88.6 COG0507@1|root,COG0507@2|Bacteria,1R1AT@1224|Proteobacteria,2U1ZX@28211|Alphaproteobacteria 28211|Alphaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - - - - - - - - - - Terminase_6 k59_243129_1 1122137.AQXF01000002_gene217 1.06e-08 67.4 COG3064@1|root,COG3064@2|Bacteria,1NQ5T@1224|Proteobacteria,2UK7G@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Membrane - - - - - - - - - - - - PTR k59_121793_8 401526.TcarDRAFT_1284 3.38e-08 65.9 COG3170@1|root,COG3170@2|Bacteria,1U52E@1239|Firmicutes,4H6S0@909932|Negativicutes 909932|Negativicutes NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - k59_243221_2 765911.Thivi_2068 0.000751 45.1 2DM17@1|root,319VU@2|Bacteria,1R6RI@1224|Proteobacteria,1T0YN@1236|Gammaproteobacteria 1236|Gammaproteobacteria L PFAM GIY-YIG catalytic domain - - - - - - - - - - - - - k59_61095_1 186617.M9M8L2_9VIRU 9.93e-71 231.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_146130_2 1096546.WYO_0201 2.04e-37 143.0 28P6A@1|root,2ZC10@2|Bacteria,1RBZE@1224|Proteobacteria,2UQEG@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_133934_3 1034115.G1D5E6_9CAUD 5.76e-20 85.9 4QE8A@10239|Viruses,4QXTV@35237|dsDNA viruses no RNA stage,4QS6D@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_121795_5 1234888.K0A2J2_9VIRU 8.86e-143 426.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_365545_1 1121033.AUCF01000004_gene4989 3.85e-09 57.8 28NA5@1|root,2ZBDZ@2|Bacteria,1MXY5@1224|Proteobacteria,2TYZX@28211|Alphaproteobacteria,2JWJ4@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_220219_2 1609634.A0A0C5AFV4_9VIRU 1.05e-59 201.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_305112_1 1234888.K0A2J2_9VIRU 5.42e-61 204.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_220221_1 1379709.S5TMV0_9CIRC 1.41e-25 108.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_62243_1 443254.Marpi_0094 1.22e-08 66.2 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GCCM@200918|Thermotogae 200918|Thermotogae L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_37692_2 1385658.U5KPZ6_9VIRU 3.21e-169 497.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_25626_1 691965.D4P7I3_9CAUD 1.91e-185 560.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_98554_2 1986029.Q9MBM6_9VIRU 2.15e-12 67.4 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_13100_1 1437448.AZRT01000037_gene3265 4.63e-14 77.4 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2TSTN@28211|Alphaproteobacteria,1J2MA@118882|Brucellaceae 28211|Alphaproteobacteria K ParB-like nuclease domain parB - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_25629_2 1133293.H2EIC1_9CAUD 3.9e-18 87.8 4QAUC@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_268665_6 1173020.Cha6605_6275 1.04e-13 80.1 2CC4J@1|root,2Z7W8@2|Bacteria,1G4C9@1117|Cyanobacteria 1117|Cyanobacteria S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_159391_1 1609634.A0A0C5AFV4_9VIRU 3.97e-37 142.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_147267_1 1391038.T1YSF1_9VIRU 3.17e-15 73.9 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_147267_2 1795995.A0A140CTL4_9CIRC 0.000199 47.4 4QHFI@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_135809_1 1121098.HMPREF1534_03448 5.93e-09 54.3 28P3F@1|root,2ZBZ4@2|Bacteria,4NMPC@976|Bacteroidetes,2FSJ3@200643|Bacteroidia,4AR09@815|Bacteroidaceae 976|Bacteroidetes - - - - - - - - - - - - - - - k59_354695_1 551790.B5BTW0_9CAUD 7.97e-06 53.9 4QE7X@10239|Viruses,4QVF0@35237|dsDNA viruses no RNA stage,4QPUM@28883|Caudovirales,4QP17@10744|Podoviridae 10744|Podoviridae S Cytidine and deoxycytidylate deaminase zinc-binding region - - - - - - - - - - - - - k59_282699_1 907931.AEIZ01000015_gene1144 1.71e-22 105.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,4AWR6@81850|Leuconostocaceae 91061|Bacilli L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A k59_26660_1 1380391.JIAS01000005_gene2437 1.82e-53 184.0 COG5323@1|root,COG5323@2|Bacteria,1R0EP@1224|Proteobacteria,2TYQ7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - - k59_366627_1 1379708.S5SYC3_9CIRC 4.83e-16 82.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_26662_1 216595.PFLU_2867 6.44e-58 197.0 COG4626@1|root,COG4626@2|Bacteria,1R2FH@1224|Proteobacteria,1RN1F@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Terminase - - - - - - - - - - - - - k59_2401_5 1461580.CCAS010000060_gene3848 3.19e-11 67.4 COG3409@1|root,COG3409@2|Bacteria,1TPV1@1239|Firmicutes,4HI6Q@91061|Bacilli 91061|Bacilli M Domain of unknown function (DUF1906) - - - - - - - - - - - - DUF1906,PG_binding_1 k59_2401_9 696748.ASU2_06645 8.6e-05 50.8 COG5295@1|root,COG5295@2|Bacteria,1N338@1224|Proteobacteria,1RPXV@1236|Gammaproteobacteria,1Y7F2@135625|Pasteurellales 135625|Pasteurellales UW autotransporter adhesin - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - ESPR,YadA_anchor,YadA_head,YadA_stalk k59_13835_1 351016.RAZWK3B_15543 1.87e-05 52.8 COG1783@1|root,COG1783@2|Bacteria,1QZB1@1224|Proteobacteria,2TY6V@28211|Alphaproteobacteria 2|Bacteria S Terminase-like family - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_6 k59_13835_3 532075.B3VCW6_9CAUD 7.11e-24 95.5 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QPEB@28883|Caudovirales,4QNC3@10744|Podoviridae 10744|Podoviridae S endonuclease activity - - - - - - - - - - - - - k59_245157_4 756272.Plabr_0235 1.67e-45 163.0 2CJK2@1|root,33ZA7@2|Bacteria,2J3FD@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_111684_2 1609634.A0A0C5AFV4_9VIRU 2.19e-127 389.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_39672_2 1415780.JPOG01000001_gene1744 4.33e-20 103.0 COG0454@1|root,COG0827@1|root,COG1040@1|root,COG3087@1|root,COG0456@2|Bacteria,COG0827@2|Bacteria,COG1040@2|Bacteria,COG3087@2|Bacteria,1PI1K@1224|Proteobacteria,1T6BU@1236|Gammaproteobacteria,1XB7I@135614|Xanthomonadales 135614|Xanthomonadales D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - - - - - - - - - - - k59_39672_3 1219049.SP5_068_01130 6.61e-55 198.0 2CC8M@1|root,308VJ@2|Bacteria,1R789@1224|Proteobacteria,2U2NB@28211|Alphaproteobacteria,2K46P@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - k59_112815_3 1540095.A0A0A0YP73_9CAUD 1.04e-09 60.8 4QAVB@10239|Viruses,4QPIJ@28883|Caudovirales,4QI48@10662|Myoviridae 10662|Myoviridae S defense response to bacterium - - - - - - - - - - - - - k59_319798_1 1692249.A0A0K1RLN8_9CIRC 5.13e-24 103.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_27882_2 573065.Astex_0887 9.43e-28 108.0 COG1738@1|root,COG1738@2|Bacteria,1N0RB@1224|Proteobacteria,2UCY9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Putative vitamin uptake transporter - - - - - - - - - - - - Vut_1 k59_184658_1 1157634.KB912966_gene2185 1.66e-45 153.0 arCOG05626@1|root,32V4D@2|Bacteria,2I38M@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_343703_1 1609634.A0A0C5AFT2_9VIRU 4.24e-79 245.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_332005_1 1100814.G8FS12_9CAUD 2.15e-45 171.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_39674_1 1131730.BAVI_00810 1.64e-07 58.2 COG1051@1|root,COG1051@2|Bacteria,1V3T8@1239|Firmicutes,4HH2F@91061|Bacilli,1ZGCQ@1386|Bacillus 91061|Bacilli F Belongs to the Nudix hydrolase family - - - - - - - - - - - - NUDIX k59_88698_1 1522072.IL54_3330 1.88e-07 62.0 COG0010@1|root,COG0010@2|Bacteria 2|Bacteria E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines - - 3.5.3.11 ko:K01480 ko00330,ko01100,map00330,map01100 M00133 R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase k59_284136_4 1304877.KI519399_gene5021 1.58e-184 536.0 COG5362@1|root,COG5362@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Terminase_6C k59_112816_1 1609634.A0A0C5AFT2_9VIRU 1e-110 332.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_210765_3 1265502.KB905934_gene3161 2.91e-58 186.0 COG0817@1|root,COG0817@2|Bacteria,1RCYK@1224|Proteobacteria,2VHSV@28216|Betaproteobacteria,4ACUZ@80864|Comamonadaceae 28216|Betaproteobacteria L 16.7 kDa protein gp11 SWALL Q9JMN0 (EMBL AB036666) (151 aa) fasta scores E() 1.7e-13, 36.61 id in 142 aa, and to Ralstonia solanacearum bacteriophage-related protein rsc3228 or rs02445 SWALL Q8XUG0 (EMBL AL646074) (154 aa) fasta scores E() 1.1e-21, 46.35 id in 151 aa - - - - - - - - - - - - - k59_234544_1 1123057.P872_11390 1.02e-19 88.2 COG0417@1|root,COG0417@2|Bacteria,4PKQ5@976|Bacteroidetes,47KCR@768503|Cytophagia 976|Bacteroidetes L 3'-5' exonuclease related to the exonuclease domain of PolB - - - ko:K07501 - - - - ko00000 - - - DNA_pol_B_exo2 k59_234544_2 1444306.JFZC01000099_gene1137 0.000124 42.4 COG1476@1|root,COG1476@2|Bacteria,1VFN1@1239|Firmicutes,4HSHB@91061|Bacilli 91061|Bacilli K Helix-turn-helix - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 k59_184767_1 268747.Q58LL7_BPPRS 7.79e-10 64.3 4QCZH@10239|Viruses,4QXH3@35237|dsDNA viruses no RNA stage,4QPND@28883|Caudovirales,4QI11@10662|Myoviridae 10662|Myoviridae S Bacteriophage T4 gp9/10-like protein - GO:0005575,GO:0019012,GO:0044423,GO:0098015,GO:0098025 - - - - - - - - - - - k59_64839_1 1341151.ASZU01000008_gene1531 5.68e-67 223.0 COG1783@1|root,COG1783@2|Bacteria,1VK0H@1239|Firmicutes,4HQ2H@91061|Bacilli 91061|Bacilli S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_173891_2 1234888.K0A2J2_9VIRU 5.82e-102 316.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_345196_1 717785.HYPMC_1239 7.3e-72 234.0 2CK1H@1|root,33WMM@2|Bacteria,1RF5H@1224|Proteobacteria,2UMV7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_77841_6 1082931.KKY_3127 2.37e-15 71.6 2EK5N@1|root,3193T@2|Bacteria,1Q1QN@1224|Proteobacteria,2VDPN@28211|Alphaproteobacteria,3N987@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_126738_2 411464.DESPIG_01281 1.35e-05 56.6 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,42Z58@68525|delta/epsilon subdivisions,2WTW4@28221|Deltaproteobacteria,2M8HG@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_126738_3 78398.KS43_20360 5.52e-29 132.0 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,1RR0M@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_333364_1 876044.IMCC3088_1879 4.22e-99 301.0 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RMJ1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k59_175506_1 1229205.BUPH_03806 4.3e-15 79.0 COG5377@1|root,COG5377@2|Bacteria,1MWP8@1224|Proteobacteria,2VJH5@28216|Betaproteobacteria,1K2RX@119060|Burkholderiaceae 28216|Betaproteobacteria L YqaJ-like viral recombinase domain - - - - - - - - - - - - YqaJ k59_248014_2 1223523.H340_01349 7.82e-12 68.6 2DC0I@1|root,2ZC7X@2|Bacteria,2IG5R@201174|Actinobacteria 201174|Actinobacteria S P22 coat protein - gene protein 5 - - - - - - - - - - - - P22_CoatProtein k59_212292_3 145579.REP_BPPHM 3.42e-05 49.3 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_163279_2 1057002.KB905370_gene5890 6.27e-28 123.0 COG3064@1|root,COG3064@2|Bacteria,1R6JV@1224|Proteobacteria,2U5NE@28211|Alphaproteobacteria,4BCUU@82115|Rhizobiaceae 28211|Alphaproteobacteria M Membrane - - - - - - - - - - - - - k59_260017_1 1462526.BN990_01842 6.44e-08 57.4 2C1BV@1|root,32ZTD@2|Bacteria,1VGE5@1239|Firmicutes,4HPF9@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - GcrA k59_175508_3 203124.Tery_3529 2.28e-20 90.5 COG0457@1|root,COG1262@1|root,COG0457@2|Bacteria,COG1262@2|Bacteria,1GQW8@1117|Cyanobacteria,1H81P@1150|Oscillatoriales 1117|Cyanobacteria S Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase,TPR_1,TPR_8 k59_90421_1 1234888.K0A2J2_9VIRU 3.42e-35 137.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_345378_1 1172188.KB911820_gene2847 2.18e-08 55.1 COG3567@1|root,COG3567@2|Bacteria,2H48H@201174|Actinobacteria 201174|Actinobacteria S Phage portal protein, SPP1 Gp6-like - - - - - - - - - - - - Phage_prot_Gp6 k59_152690_1 525897.Dbac_0117 3.76e-40 156.0 COG1215@1|root,COG1887@1|root,COG1215@2|Bacteria,COG1887@2|Bacteria,1QUJX@1224|Proteobacteria,42VVR@68525|delta/epsilon subdivisions,2X6XK@28221|Deltaproteobacteria,2MCCT@213115|Desulfovibrionales 28221|Deltaproteobacteria M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_1,Glycos_transf_2 k59_67625_1 1219035.NT2_13_00580 1.51e-44 167.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_273970_1 1112214.AHIS01000083_gene3634 7e-35 130.0 COG0740@1|root,COG0740@2|Bacteria,1MUQ9@1224|Proteobacteria,2U37W@28211|Alphaproteobacteria,2K3UN@204457|Sphingomonadales 204457|Sphingomonadales OU Belongs to the peptidase S14 family - - - - - - - - - - - - CLP_protease k59_273970_2 1028806.GGE_0916 0.000268 48.9 COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,1RPB0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S portal protein - - - - - - - - - - - - Phage_portal k59_55210_1 1234888.K0A2J2_9VIRU 1.53e-45 164.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_17659_1 1385658.U5KPZ6_9VIRU 2.43e-24 103.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_17659_2 105154.Q9MBU3_9VIRU 3.76e-13 68.9 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_261295_2 397945.Aave_1710 2.91e-31 119.0 2AFJZ@1|root,336NA@2|Bacteria,1N9T7@1224|Proteobacteria,2VZ0D@28216|Betaproteobacteria,4AIWD@80864|Comamonadaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_186596_1 1336208.JADY01000011_gene3093 2.97e-08 60.5 COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2TR0Q@28211|Alphaproteobacteria,2JQZC@204441|Rhodospirillales 204441|Rhodospirillales M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k59_17667_2 1410670.JHXF01000015_gene2274 6.47e-15 77.4 COG3378@1|root,COG4983@1|root,COG3378@2|Bacteria,COG4983@2|Bacteria,1TQP9@1239|Firmicutes,24AY6@186801|Clostridia,3WHX7@541000|Ruminococcaceae 186801|Clostridia S Phage plasmid primase, P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,PriCT_1,Prim-Pol k59_115599_2 1201035.KE007212_gene1417 6.01e-42 163.0 2CC8M@1|root,308VJ@2|Bacteria,1R789@1224|Proteobacteria,2U2NB@28211|Alphaproteobacteria,48TVI@772|Bartonellaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_103908_2 1455626.W5ZKV0_9CIRC 7.43e-26 111.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_382959_37 1232410.KI421421_gene3733 2.04e-27 127.0 COG1196@1|root,COG3941@1|root,COG1196@2|Bacteria,COG3941@2|Bacteria,1NTAQ@1224|Proteobacteria,42YU4@68525|delta/epsilon subdivisions,2WUGD@28221|Deltaproteobacteria,43U9F@69541|Desulfuromonadales 28221|Deltaproteobacteria D nuclear chromosome segregation - - - - - - - - - - - - - k59_382959_45 429009.Adeg_1126 0.000386 48.5 COG2227@1|root,COG2227@2|Bacteria,1UKDG@1239|Firmicutes 1239|Firmicutes H Methionine biosynthesis protein MetW - - - - - - - - - - - - Methyltransf_23 k59_382959_54 745776.DGo_CA1966 7.97e-111 339.0 COG1783@1|root,COG1783@2|Bacteria 2|Bacteria S DNA packaging - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_382959_59 742725.HMPREF9450_00200 4.87e-23 112.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,2FM8X@200643|Bacteroidia,22U0S@171550|Rikenellaceae 976|Bacteroidetes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_382959_60 701347.Entcl_1076 9.65e-09 63.5 COG0207@1|root,COG0207@2|Bacteria,1RA8U@1224|Proteobacteria,1S4IG@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Thymidylate synthase - - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k59_382959_61 938289.CAJN020000002_gene799 2.08e-25 101.0 COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia 186801|Clostridia F cytidine and deoxycytidylate deaminase zinc-binding region comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_382959_63 563192.HMPREF0179_01548 3.53e-19 100.0 COG3378@1|root,COG3378@2|Bacteria,1MV7I@1224|Proteobacteria,42QNW@68525|delta/epsilon subdivisions,2WMSE@28221|Deltaproteobacteria,2M9CB@213115|Desulfovibrionales 28221|Deltaproteobacteria L primase, P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N k59_81455_2 34007.IT40_07655 6.7e-54 198.0 2CV95@1|root,32SX6@2|Bacteria,1N2KM@1224|Proteobacteria,2UEE5@28211|Alphaproteobacteria,2PWVC@265|Paracoccus 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_105449_2 101510.RHA1_ro11009 2.48e-28 117.0 COG1857@1|root,COG1857@2|Bacteria,2IE66@201174|Actinobacteria,4G134@85025|Nocardiaceae 201174|Actinobacteria L crispr-associated protein - - - - - - - - - - - - RAMPs k59_117351_1 1192034.CAP_1091 0.000157 48.1 COG0507@1|root,COG0507@2|Bacteria,1R1AT@1224|Proteobacteria,42UU6@68525|delta/epsilon subdivisions,2X85I@28221|Deltaproteobacteria 28221|Deltaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - - - - - - - - - - - k59_187850_1 1210884.HG799464_gene10909 2.35e-85 273.0 COG2425@1|root,COG2425@2|Bacteria 2|Bacteria S positive regulation of ATPase activity coxE - - - - - - - - - - - VWA_2,VWA_CoxE k59_300686_1 412597.AEPN01000037_gene221 4.46e-44 157.0 2CDQ7@1|root,2Z7KV@2|Bacteria,1MY2D@1224|Proteobacteria,2TR92@28211|Alphaproteobacteria,2PVIJ@265|Paracoccus 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_215850_1 1144305.PMI02_04875 2.22e-43 164.0 COG5412@1|root,COG5412@2|Bacteria,1RACA@1224|Proteobacteria,2U6B3@28211|Alphaproteobacteria,2K1YQ@204457|Sphingomonadales 204457|Sphingomonadales D Phage tail tape measure protein TP901 - - - - - - - - - - - - - k59_56997_2 1126627.BAWE01000004_gene4279 2.97e-89 304.0 2DUMH@1|root,33R9V@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_33147_2 1234888.K0A2J2_9VIRU 1.04e-21 94.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_179100_1 574087.Acear_2325 1.13e-35 135.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,3WANE@53433|Halanaerobiales 186801|Clostridia L Replicative DNA helicase dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_105715_2 626887.J057_01900 1.37e-11 66.2 2C2XN@1|root,32GT6@2|Bacteria,1REZE@1224|Proteobacteria,1SG9Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria S ERF superfamily - - - - - - - - - - - - ERF k59_312507_4 1437882.AZRU01000104_gene3919 1.75e-58 200.0 COG2404@1|root,COG2404@2|Bacteria,1MXEH@1224|Proteobacteria,1SADM@1236|Gammaproteobacteria,1YI8A@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S phosphoesterase DHHA1 - - - - - - - - - - - - DHHA1 k59_179359_1 1692244.A0A0K1RLR5_9CIRC 1.2e-12 70.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_349164_1 575540.Isop_2435 2.62e-21 97.4 COG5511@1|root,COG5511@2|Bacteria,2IZFA@203682|Planctomycetes 203682|Planctomycetes S Phage portal protein, lambda family - - - - - - - - - - - - Phage_portal_2 k59_166522_1 521000.PROVRETT_05519 2.32e-14 81.3 28IJ1@1|root,2Z8K0@2|Bacteria,1R5PC@1224|Proteobacteria,1S1ER@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_81729_1 1123312.KB904575_gene72 1.22e-27 115.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H9YP@91061|Bacilli 91061|Bacilli L SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_253239_3 1499967.BAYZ01000036_gene2417 9.07e-10 59.3 COG1793@1|root,COG1793@2|Bacteria 2|Bacteria L dna ligase - - 6.5.1.1 ko:K01971 ko03450,map03450 - R00381 RC00005 ko00000,ko00001,ko01000,ko03400 - - - DNA_ligase_A_C,DNA_ligase_A_M,WGR k59_314282_2 1234888.K0A2J2_9VIRU 9.9e-30 117.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_302741_3 1609634.A0A0C5AFV4_9VIRU 3.1e-77 247.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_264957_1 1504823.CCMM01000006_gene403 2.52e-15 80.5 COG0463@1|root,COG0463@2|Bacteria,2NPWT@2323|unclassified Bacteria 2|Bacteria M Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - Glycos_transf_2,TPR_1,TPR_16,TPR_2,TPR_8 k59_21225_1 1430440.MGMSRv2_1973 2.24e-49 181.0 COG3378@1|root,COG3378@2|Bacteria,1PHUS@1224|Proteobacteria,2V9QS@28211|Alphaproteobacteria,2JXE8@204441|Rhodospirillales 204441|Rhodospirillales S D5 N terminal like - - - ko:K06919 - - - - ko00000 - - - D5_N k59_264959_1 1385658.U5KPZ6_9VIRU 4.32e-83 266.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_218059_2 1385658.U5KPZ6_9VIRU 2.1e-158 465.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_374530_2 279238.Saro_3022 2.01e-09 57.8 2C0VP@1|root,32ZQ9@2|Bacteria,1NENB@1224|Proteobacteria,2UGGI@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_314291_1 1353531.AZNX01000020_gene4384 9.83e-31 116.0 2A4D4@1|root,30SYX@2|Bacteria,1PCIM@1224|Proteobacteria,2USSQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_96514_1 795666.MW7_1318 1.36e-13 74.3 COG0863@1|root,COG2189@1|root,COG0863@2|Bacteria,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,2VI5P@28216|Betaproteobacteria,1KGWF@119060|Burkholderiaceae 28216|Betaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_35109_1 1564096.A0A0A0YRA9_9CAUD 1.6e-82 297.0 4QEE7@10239|Viruses,4QPT7@28883|Caudovirales,4QI2X@10662|Myoviridae 10662|Myoviridae S Pfam:DUF4815 - - - - - - - - - - - - - k59_35109_3 1357714.A0A067XRI9_9CAUD 4.4e-47 162.0 4QCS3@10239|Viruses,4QY7T@35237|dsDNA viruses no RNA stage,4QU2E@28883|Caudovirales,4QKJF@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_107538_3 1123401.JHYQ01000040_gene2434 1.96e-36 139.0 COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,1S28H@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) yjbJ - - - - - - - - - - - DUF4124,SLT k59_361983_2 1165094.RINTHH_3920 2.53e-32 122.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_386364_2 1229172.JQFA01000002_gene4632 2.06e-16 82.0 COG3772@1|root,COG3772@2|Bacteria,1G7YF@1117|Cyanobacteria,1HASB@1150|Oscillatoriales 1117|Cyanobacteria M Phage lysozyme - - - - - - - - - - - - PG_binding_1,Phage_lysozyme k59_388135_3 1385658.U5KNR1_9VIRU 4.99e-11 66.6 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_254915_2 909663.KI867149_gene3275 3.04e-12 68.6 2DMVU@1|root,32TZX@2|Bacteria,1ND1A@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_352336_1 444875.E3SMD8_9CAUD 2.1e-20 87.8 4QD0J@10239|Viruses,4R0A5@35237|dsDNA viruses no RNA stage,4QSK9@28883|Caudovirales,4QNR4@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_169819_1 1121921.KB898711_gene2089 2.49e-36 129.0 COG4508@1|root,COG4508@2|Bacteria,1RAX1@1224|Proteobacteria,1RYFG@1236|Gammaproteobacteria,2PNB5@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S dUTPase dut - - - - - - - - - - - dUTPase_2 k59_255109_1 428125.CLOLEP_01409 1.02e-276 769.0 COG4626@1|root,COG4626@2|Bacteria,1TT9I@1239|Firmicutes,24AFK@186801|Clostridia,3WNF4@541000|Ruminococcaceae 186801|Clostridia S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_388290_1 1618257.A0A0C5IBI9_9CIRC 1.38e-29 120.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_121271_2 1618242.A0A0C5IBR9_9CIRC 6.71e-72 231.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_266725_2 1692244.A0A0K1RLR5_9CIRC 1.59e-60 201.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_170107_3 1379725.S5SYG4_9CIRC 2.58e-31 122.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_376631_1 105154.Q9MBU6_9VIRU 4.11e-120 361.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_376631_2 105154.Q9MBU3_9VIRU 0.000936 47.8 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_376631_4 1385658.U5KNR1_9VIRU 6.84e-77 244.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_376631_6 1609634.A0A0C5AFV4_9VIRU 8.28e-79 253.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_279376_1 1379709.S5TMV0_9CIRC 7.88e-42 153.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_243176_21 926551.KB900735_gene1489 1.13e-22 94.0 COG4696@1|root,COG4696@2|Bacteria,4NNW2@976|Bacteroidetes,1I23U@117743|Flavobacteriia,1ET44@1016|Capnocytophaga 976|Bacteroidetes S Phosphoribosyl-ATP pyrophosphohydrolase - - - - - - - - - - - - PRA-PH k59_243176_24 365044.Pnap_1478 3.26e-19 102.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2VJ57@28216|Betaproteobacteria,4AAFC@80864|Comamonadaceae 28216|Betaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_243176_25 1151014.A0A067YBD2_9CAUD 4.76e-19 87.8 4QG29@10239|Viruses,4QZ7B@35237|dsDNA viruses no RNA stage,4QT35@28883|Caudovirales,4QNCJ@10744|Podoviridae 10744|Podoviridae S ATP binding - - - - - - - - - - - - - k59_243176_26 1121344.JHZO01000007_gene2048 3.2e-34 144.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia,3WGP3@541000|Ruminococcaceae 186801|Clostridia L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k59_48947_2 1166948.JPZL01000002_gene1845 8.99e-132 385.0 28W6R@1|root,2ZI7D@2|Bacteria,1N49N@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_12367_1 298654.FraEuI1c_0194 1.85e-38 140.0 COG1089@1|root,COG1089@2|Bacteria,2GNMA@201174|Actinobacteria,4ERDN@85013|Frankiales 201174|Actinobacteria M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose gmd - 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd k59_298_2 1234888.K0A2R8_9VIRU 9.16e-44 160.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_298_4 1234888.K0A2J2_9VIRU 3.38e-130 393.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_364743_2 1380354.JIAN01000007_gene175 5.1e-16 81.6 COG1191@1|root,COG1191@2|Bacteria,2GKBK@201174|Actinobacteria 201174|Actinobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released whiG - - ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 - - - ko00000,ko00001,ko02035,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k59_364743_3 1470593.BW43_04190 7.5e-29 112.0 COG1896@1|root,COG1896@2|Bacteria,1RACF@1224|Proteobacteria,1S2SY@1236|Gammaproteobacteria 1236|Gammaproteobacteria S 5'-deoxynucleotidase activity yfdR GO:0002953,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897 - ko:K06952 - - - - ko00000 - - - - k59_328362_2 1609634.A0A0C5ANA6_9VIRU 3.8e-11 67.8 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_12614_1 1609634.A0A0C5ANA6_9VIRU 2.63e-07 56.2 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_340687_1 1121434.AULY01000011_gene1824 1.63e-67 221.0 COG5362@1|root,COG5362@2|Bacteria,1PYY9@1224|Proteobacteria,435M3@68525|delta/epsilon subdivisions,2WZZT@28221|Deltaproteobacteria,2M981@213115|Desulfovibrionales 28221|Deltaproteobacteria S TIGRFAM Phage - - - - - - - - - - - - - k59_73529_1 1000565.METUNv1_03733 1.04e-17 89.4 COG1475@1|root,COG1475@2|Bacteria,1R3Q6@1224|Proteobacteria,2VRKG@28216|Betaproteobacteria,2KXDD@206389|Rhodocyclales 206389|Rhodocyclales K ParB-like nuclease domain - - - - - - - - - - - - ParBc k59_134126_1 717774.Marme_1832 6.06e-15 75.9 COG0741@1|root,COG0741@2|Bacteria,1QZ7X@1224|Proteobacteria,1T417@1236|Gammaproteobacteria 1236|Gammaproteobacteria M lytic transglycosylase activity - - - - - - - - - - - - - k59_109918_3 642492.Clole_1479 1.45e-20 94.4 COG3935@1|root,COG3935@2|Bacteria,1W6YJ@1239|Firmicutes,24P7D@186801|Clostridia 186801|Clostridia L DnaD domain protein - - - - - - - - - - - - - k59_61465_1 1379708.S5SYC3_9CIRC 9.67e-35 128.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_328680_1 1556290.A0A0A0RQH0_9CAUD 3.65e-19 95.9 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_328680_10 1556290.A0A0A0RL61_9CAUD 7.89e-67 223.0 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - GO:0005575,GO:0019012,GO:0019028,GO:0032991,GO:0044423,GO:0046806 - - - - - - - - - - - k59_328680_12 1556290.A0A0A0RM05_9CAUD 2.34e-136 411.0 4QAYV@10239|Viruses,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - k59_243427_1 1079986.JH164857_gene7873 7.58e-31 124.0 COG0210@1|root,COG0210@2|Bacteria,2GU9Z@201174|Actinobacteria 201174|Actinobacteria L UvrD-like helicase C-terminal domain - - - - - - - - - - - - AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2 k59_61555_1 428125.CLOLEP_01379 9.76e-25 102.0 COG0553@1|root,COG0553@2|Bacteria,1TS9W@1239|Firmicutes,24CGX@186801|Clostridia,3WN6X@541000|Ruminococcaceae 186801|Clostridia KL Helicase conserved C-terminal domain - - - - - - - - - - - - - k59_61555_3 742740.HMPREF9474_02280 2.91e-32 115.0 2CGGB@1|root,32UNH@2|Bacteria,1VD9W@1239|Firmicutes,24MWC@186801|Clostridia,2235P@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_24916_4 1127673.GLIP_3386 3.01e-14 72.8 2AD08@1|root,312N7@2|Bacteria,1NDC4@1224|Proteobacteria 1224|Proteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_158751_1 227377.CBU_0271 3.28e-58 184.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,1JED6@118969|Legionellales 118969|Legionellales L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_280288_1 347834.RHE_CH01097 3.56e-40 146.0 28NGF@1|root,2ZBII@2|Bacteria,1R9KY@1224|Proteobacteria,2U1P7@28211|Alphaproteobacteria,4B747@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_231509_3 105154.Q9MBU0_9VIRU 4.42e-16 82.8 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_74463_1 1379725.S5TMY9_9CIRC 2.24e-25 110.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_37851_1 1385658.U5KPZ6_9VIRU 2.08e-116 353.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_37851_5 1609634.A0A0C5AFT2_9VIRU 9.75e-53 182.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_159577_1 307480.IW16_26365 1.83e-09 62.4 COG1961@1|root,COG1961@2|Bacteria,4NJM8@976|Bacteroidetes,1I0IY@117743|Flavobacteriia,3ZRIH@59732|Chryseobacterium 976|Bacteroidetes L Resolvase, N terminal domain - - - - - - - - - - - - HTH_7,Resolvase k59_305411_2 1121440.AUMA01000011_gene2485 1.81e-06 53.1 COG0451@1|root,COG0451@2|Bacteria,1QUEV@1224|Proteobacteria,43BNE@68525|delta/epsilon subdivisions,2WKIX@28221|Deltaproteobacteria,2M9U6@213115|Desulfovibrionales 28221|Deltaproteobacteria M PFAM NAD-dependent epimerase dehydratase - - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd k59_244291_4 497965.Cyan7822_1878 8.63e-09 62.8 COG0863@1|root,COG2189@1|root,COG0863@2|Bacteria,COG2189@2|Bacteria,1G3H1@1117|Cyanobacteria,3KK61@43988|Cyanothece 1117|Cyanobacteria H PFAM DNA methylase N-4 N-6 domain protein - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_268814_1 90814.KL370891_gene1642 1.09e-13 75.5 28H5T@1|root,2Z7IB@2|Bacteria,1N7V9@1224|Proteobacteria,1S23F@1236|Gammaproteobacteria,460Z8@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - - k59_25828_1 1215092.PA6_046_00270 7.45e-21 83.6 28QDM@1|root,2ZCVZ@2|Bacteria,1P5MR@1224|Proteobacteria,1SW6Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_25828_2 1166016.W5S_2328 1.52e-125 371.0 2CI0W@1|root,2Z81W@2|Bacteria,1R9FZ@1224|Proteobacteria,1S0NA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage X family - - - - - - - - - - - - Phage_CRI,Phage_X k59_329662_5 1609634.A0A0C5AFV4_9VIRU 4.67e-169 496.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_25829_2 1234888.K0A2R8_9VIRU 4.27e-13 72.4 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_365789_1 441620.Mpop_3229 3.95e-19 98.2 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,2TVG8@28211|Alphaproteobacteria,1JTJN@119045|Methylobacteriaceae 28211|Alphaproteobacteria L Helix-hairpin-helix containing domain - - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,UvrD_C_2,Viral_helicase1 k59_37937_1 1692255.A0A0K1RL52_9CIRC 5.35e-18 86.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_305421_1 743836.AYNA01000129_gene1504 2.79e-73 233.0 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,2TQWC@28211|Alphaproteobacteria,36XBP@31993|Methylocystaceae 28211|Alphaproteobacteria L PIF1-like helicase recD - 3.1.11.5 ko:K01144 - - - - ko00000,ko01000 - - - AAA_30,UvrD_C_2 k59_220508_1 439375.Oant_0230 1.69e-42 152.0 COG0270@1|root,COG0270@2|Bacteria,1R5MR@1224|Proteobacteria,2U53Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_13232_4 1234888.K0A2J2_9VIRU 7.93e-100 311.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_124363_4 1340810.V5UTB4_9CAUD 2.34e-06 58.2 4QB3T@10239|Viruses,4QWCJ@35237|dsDNA viruses no RNA stage,4QS7B@28883|Caudovirales,4QK0J@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_221581_4 1121468.AUBR01000008_gene2081 2.98e-05 47.4 COG4570@1|root,COG4570@2|Bacteria,1UDK7@1239|Firmicutes,24T1T@186801|Clostridia,42INU@68295|Thermoanaerobacterales 186801|Clostridia L PFAM endodeoxyribonuclease RusA - - 3.1.22.4 ko:K01160 - - - - ko00000,ko01000,ko03400 - - - RusA k59_379153_1 1306174.JODP01000021_gene266 7.94e-26 110.0 COG4124@1|root,COG4124@2|Bacteria,2GN8K@201174|Actinobacteria 201174|Actinobacteria G Belongs to the glycosyl hydrolase 26 family - - - - - - - - - - - - Glyco_hydro_26 k59_136176_2 1262914.BN533_00198 6.84e-12 73.9 COG4695@1|root,COG4695@2|Bacteria,1TP8B@1239|Firmicutes 1239|Firmicutes OU Phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_197059_1 1051675.G0YQC3_9CAUD 1.59e-15 81.3 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_148171_4 979556.MTES_3251 9.13e-45 150.0 arCOG05626@1|root,2Z9D9@2|Bacteria,2IIAB@201174|Actinobacteria,4FS1R@85023|Microbacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_136284_2 1343158.SACS_1410 5.45e-16 81.3 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,2TU12@28211|Alphaproteobacteria,2JPDR@204441|Rhodospirillales 204441|Rhodospirillales H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose hldE - 2.7.1.167,2.7.7.70 ko:K03272 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_like,PfkB k59_366830_2 1121459.AQXE01000001_gene2769 8.47e-15 76.6 2AFZH@1|root,3163D@2|Bacteria,1RJUP@1224|Proteobacteria,42ZBP@68525|delta/epsilon subdivisions,2WTYW@28221|Deltaproteobacteria,2MDNE@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_269772_1 2003327.CAPSD_BPCHP 1.13e-99 317.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_269772_6 1385658.U5KPZ6_9VIRU 1.28e-37 140.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_160758_2 1120963.KB894514_gene385 3.21e-25 99.8 2CPEB@1|root,32SIW@2|Bacteria,1MZE0@1224|Proteobacteria,1SARU@1236|Gammaproteobacteria,2Q4T5@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_343768_2 483216.BACEGG_02723 1.16e-06 57.8 2BP9Z@1|root,32I1T@2|Bacteria,4PE07@976|Bacteroidetes,2FW3U@200643|Bacteroidia,4AUA1@815|Bacteroidaceae 976|Bacteroidetes - - - - - - - - - - - - - - - k59_27951_1 1556290.A0A0A0RL96_9CAUD 4.13e-113 350.0 4QGMJ@10239|Viruses,4QSYG@28883|Caudovirales,4QM5B@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_88757_1 1057002.KB905370_gene3601 6.82e-33 131.0 COG0286@1|root,COG0553@1|root,COG0286@2|Bacteria,COG0553@2|Bacteria,1MXQH@1224|Proteobacteria,2TR5V@28211|Alphaproteobacteria,4BC7I@82115|Rhizobiaceae 28211|Alphaproteobacteria KLV C-terminal domain on Strawberry notch homologue - - - - - - - - - - - - AAA_34,Helicase_C_4 k59_270790_3 1392540.P256_00728 9.31e-43 149.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,1SQ0T@1236|Gammaproteobacteria,3NSW6@468|Moraxellaceae 1236|Gammaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_332075_1 1173762.S4TU76_9CAUD 1.31e-105 329.0 4QF3C@10239|Viruses,4QWIA@35237|dsDNA viruses no RNA stage,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_258751_1 330214.NIDE2332 3.73e-32 129.0 COG0028@1|root,COG0028@2|Bacteria,3J0D6@40117|Nitrospirae 2|Bacteria H Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k59_76619_1 349521.HCH_04545 1.36e-08 62.8 COG5283@1|root,COG5283@2|Bacteria,1QZAD@1224|Proteobacteria,1RYP3@1236|Gammaproteobacteria,1XMG9@135619|Oceanospirillales 135619|Oceanospirillales D nuclear chromosome segregation - - - - - - - - - - - - - k59_149541_1 1692252.A0A0K1RL35_9CIRC 2.64e-86 261.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_101205_1 1408428.JNJP01000005_gene5 1.26e-11 67.0 2C9JF@1|root,32RPD@2|Bacteria,1N8CG@1224|Proteobacteria,42REW@68525|delta/epsilon subdivisions,2WNQ1@28221|Deltaproteobacteria,2MB30@213115|Desulfovibrionales 28221|Deltaproteobacteria S ERF superfamily - - - - - - - - - - - - ERF k59_234577_1 1380386.JIAW01000004_gene347 1.05e-35 132.0 COG3541@1|root,COG3541@2|Bacteria,2GUQV@201174|Actinobacteria,238C4@1762|Mycobacteriaceae 201174|Actinobacteria S Predicted nucleotidyltransferase - - - ko:K07074 - - - - ko00000 - - - Nuc-transf k59_198160_2 652103.Rpdx1_2535 3.88e-08 63.9 2DQ9V@1|root,335IH@2|Bacteria 2|Bacteria - - - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - - k59_212153_1 1122217.KB899582_gene1559 1.99e-40 147.0 2CC4J@1|root,2Z7W8@2|Bacteria,1UX5W@1239|Firmicutes,4H2HV@909932|Negativicutes 909932|Negativicutes S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_272200_1 132113.XP_003493950.1 1.17e-40 154.0 COG0768@1|root,2QR8J@2759|Eukaryota,39SBS@33154|Opisthokonta,3BIR4@33208|Metazoa,3DFVW@33213|Bilateria,427JX@6656|Arthropoda,3SI2G@50557|Insecta 33208|Metazoa M Penicillin-binding Protein dimerisation domain - - - - - - - - - - - - FTSW_RODA_SPOVE,PBP_dimer,SPOUT_MTase,Transpeptidase k59_175366_2 926550.CLDAP_25590 1.87e-09 58.5 COG1572@1|root,COG1572@2|Bacteria 2|Bacteria NU bacterial-type flagellum-dependent cell motility - - - - - - - - - - - - BatA,CARDB,DUF3367,DUF4091,DUF4159 k59_321276_1 1788443.A0A190WHB4_9CIRC 2.06e-21 95.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_212154_1 1327956.S4US93_9CAUD 9.18e-09 57.8 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QI6A@10662|Myoviridae 10662|Myoviridae S Ribonucleotide reductase, barrel domain - - - - - - - - - - - - - k59_212154_2 1206557.I7J3U1_9CAUD 4.29e-73 239.0 4QC2G@10239|Viruses,4QV3V@35237|dsDNA viruses no RNA stage,4QPRR@28883|Caudovirales,4QM50@10699|Siphoviridae 10699|Siphoviridae S Ribonucleotide reductase, small chain - - - - - - - - - - - - - k59_212154_3 1357714.A0A067XQR5_9CAUD 2.41e-13 65.9 4QAQV@10239|Viruses,4QUPK@35237|dsDNA viruses no RNA stage,4QPCB@28883|Caudovirales,4QHY7@10662|Myoviridae 10662|Myoviridae S protein disulfide oxidoreductase activity - - - - - - - - - - - - - k59_212154_4 1206545.S6CFB2_9CAUD 4.17e-29 114.0 4QCUC@10239|Viruses,4QY13@35237|dsDNA viruses no RNA stage,4QQ7E@28883|Caudovirales,4QIRS@10662|Myoviridae 10662|Myoviridae S endodeoxyribonuclease activity - - - - - - - - - - - - - k59_212154_5 926551.KB900735_gene1572 5.05e-30 115.0 COG2131@1|root,COG2131@2|Bacteria,4NM48@976|Bacteroidetes,1I1AE@117743|Flavobacteriia,1EQM2@1016|Capnocytophaga 976|Bacteroidetes F Cytidine and deoxycytidylate deaminase zinc-binding region comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_77882_2 864069.MicloDRAFT_00064730 6.37e-55 184.0 28PTM@1|root,2ZCIH@2|Bacteria,1RBCN@1224|Proteobacteria,2VGPG@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_235676_1 595536.ADVE02000001_gene3060 3.56e-54 202.0 COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,2TU4W@28211|Alphaproteobacteria,36Z5E@31993|Methylocystaceae 28211|Alphaproteobacteria L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_260048_1 46234.ANA_C12489 2.62e-14 76.6 COG1215@1|root,COG2890@1|root,COG1215@2|Bacteria,COG2890@2|Bacteria 2|Bacteria J protein-(glutamine-N5) methyltransferase activity - - 2.1.1.209 ko:K20541,ko:K21515 - - - - ko00000,ko01000,ko02000,ko03009 4.D.3.1.6 - - AviRa,Glycos_transf_2,Methyltransf_11,Methyltransf_31 k59_176884_3 118173.KB235914_gene1141 1.05e-45 160.0 COG2404@1|root,COG2404@2|Bacteria,1GIC1@1117|Cyanobacteria,1HG82@1150|Oscillatoriales 1117|Cyanobacteria S hydrolase activity, acting on ester bonds - - - - - - - - - - - - - k59_42790_1 478749.BRYFOR_08560 4.8e-62 214.0 COG3378@1|root,COG3378@2|Bacteria 2|Bacteria KL Phage plasmid primase P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N,DUF3854,P22_AR_N,Pox_D5 k59_79406_1 1234888.K0A2J2_9VIRU 2.59e-62 208.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_186487_1 349741.Amuc_1348 1.67e-06 55.8 COG1196@1|root,COG1196@2|Bacteria 2|Bacteria D nuclear chromosome segregation - - - - - - - - - - - - DUF1542,DUF349,DUF4446,FIVAR,GA,Gram_pos_anchor,PhageMin_Tail k59_298371_5 1618241.A0A0C5I2I4_9CIRC 1.33e-19 92.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_346928_1 105154.Q9MBU3_9VIRU 1.08e-16 82.4 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_346928_2 105154.Q9MBU6_9VIRU 9.29e-42 150.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_42978_2 457398.HMPREF0326_03026 1.52e-56 182.0 2D1GK@1|root,32TAP@2|Bacteria,1QV4T@1224|Proteobacteria,43CXG@68525|delta/epsilon subdivisions,2X85J@28221|Deltaproteobacteria,2MFAA@213115|Desulfovibrionales 28221|Deltaproteobacteria L C-5 cytosine-specific DNA methylase - - - - - - - - - - - - - k59_287797_2 1173762.S4TT79_9CAUD 2.11e-58 189.0 4QGM6@10239|Viruses,4QYNV@35237|dsDNA viruses no RNA stage,4QRH4@28883|Caudovirales,4QP0P@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_79570_1 657309.BXY_43040 1e-09 57.0 COG1226@1|root,COG1226@2|Bacteria,4NWXV@976|Bacteroidetes,2FTXS@200643|Bacteroidia,4ARYW@815|Bacteroidaceae 976|Bacteroidetes P RyR domain - - - - - - - - - - - - RyR k59_225841_1 1122217.KB899582_gene1559 1.52e-08 58.5 2CC4J@1|root,2Z7W8@2|Bacteria,1UX5W@1239|Firmicutes,4H2HV@909932|Negativicutes 909932|Negativicutes S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_287801_1 203119.Cthe_2231 5.98e-23 98.6 COG0500@1|root,COG2226@2|Bacteria,1VQ19@1239|Firmicutes 1239|Firmicutes Q TIGRFAM Pseudaminic acid biosynthesis-associated - - - - - - - - - - - - Methyltransf_11,Methyltransf_23 k59_186569_3 452637.Oter_3947 3.39e-11 70.9 COG4627@1|root,COG4627@2|Bacteria 2|Bacteria - - - - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - Glycos_transf_2,Methyltransf_11,Methyltransf_23 k59_186569_6 395495.Lcho_0484 7.78e-24 113.0 COG2227@1|root,COG2520@1|root,COG2227@2|Bacteria,COG2520@2|Bacteria 2|Bacteria J tRNA (guanine(37)-N(1))-methyltransferase activity - - - - - - - - - - - - Glycos_transf_2,Methyltransf_11,Methyltransf_21,Methyltransf_23,Methyltransf_25 k59_129742_1 105154.Q9MBU3_9VIRU 2.41e-08 59.7 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_262600_2 1265502.KB905977_gene528 2.38e-26 103.0 COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria,2VWX0@28216|Betaproteobacteria,4AIQ3@80864|Comamonadaceae 28216|Betaproteobacteria KT HNH endonuclease - - - - - - - - - - - - HNH_3 k59_8066_3 1234888.K0A2J2_9VIRU 6.45e-35 132.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_32775_2 438482.A4ZRC7_9CAUD 8.23e-26 114.0 4QNBD@10744|Podoviridae 10744|Podoviridae S outer membrane - - - - - - - - - - - - - k59_69163_2 1609634.A0A0C5AFV4_9VIRU 3.61e-38 140.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_178712_1 1385658.U5KPZ6_9VIRU 2.6e-35 136.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_178712_3 913970.F8RW84_9VIRU 5.6e-15 82.0 4QCVK@10239|Viruses,4QUMV@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_300370_1 1396418.BATQ01000151_gene2323 4.79e-12 70.1 COG4123@1|root,COG4123@2|Bacteria,46WKH@74201|Verrucomicrobia 74201|Verrucomicrobia S Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 k59_70770_2 691965.D4P7L3_9CAUD 3.1e-145 429.0 4QBH7@10239|Viruses,4QWWF@35237|dsDNA viruses no RNA stage,4QQ8R@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_70770_4 134676.ACPL_8011 5.1e-40 139.0 arCOG05626@1|root,2Z9D9@2|Bacteria,2IIAB@201174|Actinobacteria,4DMEK@85008|Micromonosporales 201174|Actinobacteria - - - - - - - - - - - - - - - k59_70770_11 665956.HMPREF1032_00648 2.12e-54 176.0 2E0G5@1|root,32W28@2|Bacteria,1VAS0@1239|Firmicutes,24NYA@186801|Clostridia,3WNKT@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_70770_12 691965.D4P7I3_9CAUD 0.0 1638.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_70770_15 691965.D4P7I0_9CAUD 9.92e-59 197.0 4QDSZ@10239|Viruses,4QXJ8@35237|dsDNA viruses no RNA stage,4QPKE@28883|Caudovirales,4QM8R@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_70770_16 691965.D4P7H8_9CAUD 1.62e-58 191.0 4QG1E@10239|Viruses,4QZE1@35237|dsDNA viruses no RNA stage,4QU6Q@28883|Caudovirales,4QMKH@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_70770_18 742733.HMPREF9469_05024 1.52e-28 109.0 2ECB3@1|root,3369E@2|Bacteria,1VEV9@1239|Firmicutes,24R69@186801|Clostridia,223I2@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_70770_19 1256908.HMPREF0373_03028 2.9e-20 85.5 2A2ID@1|root,30QVY@2|Bacteria,1V4BJ@1239|Firmicutes,25E0Y@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_70770_21 742740.HMPREF9474_02314 8.31e-55 184.0 2A0KC@1|root,30NQJ@2|Bacteria,1V3K4@1239|Firmicutes,24HYK@186801|Clostridia,222N6@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_264503_2 3218.PP1S44_312V6.1 3.16e-62 205.0 2CM75@1|root,2QPHU@2759|Eukaryota,37NYC@33090|Viridiplantae,3G7BP@35493|Streptophyta 35493|Streptophyta - - - GO:0000003,GO:0000902,GO:0000904,GO:0003006,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009653,GO:0009826,GO:0009846,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0016043,GO:0016049,GO:0022414,GO:0030154,GO:0032501,GO:0032502,GO:0032989,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0044706,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0051704,GO:0060560,GO:0071840 - - - - - - - - - - - k59_338375_3 388739.RSK20926_08742 5.24e-09 56.6 2DN11@1|root,32UU2@2|Bacteria,1NATN@1224|Proteobacteria,2UDMR@28211|Alphaproteobacteria 28211|Alphaproteobacteria S K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - - - - - - - - - - - k59_82955_1 1207063.P24_15194 2.36e-18 93.2 28ST9@1|root,2ZF32@2|Bacteria,1PA9S@1224|Proteobacteria,2UYDQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_167602_1 1173762.S4TU71_9CAUD 2.82e-10 66.2 4QFCU@10239|Viruses,4QVYH@35237|dsDNA viruses no RNA stage,4QTFF@28883|Caudovirales,4QNUH@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_34611_1 1385658.U5KPZ6_9VIRU 1.75e-57 196.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_217480_1 445683.E3SJQ4_9CAUD 6.71e-47 166.0 4QAJD@10239|Viruses,4QW4M@35237|dsDNA viruses no RNA stage,4QQ7U@28883|Caudovirales,4QIAP@10662|Myoviridae 10662|Myoviridae S gp32 DNA binding protein like - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039686,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_350379_1 1385658.U5KNR1_9VIRU 2.13e-55 186.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_229510_1 1121930.AQXG01000011_gene1697 6.3e-12 70.1 COG0593@1|root,COG0593@2|Bacteria,4NE6Q@976|Bacteroidetes,1INXF@117747|Sphingobacteriia 976|Bacteroidetes L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k59_96165_2 1449346.JQMO01000003_gene5780 2.02e-11 75.5 COG2931@1|root,COG3534@1|root,COG2931@2|Bacteria,COG3534@2|Bacteria,2I945@201174|Actinobacteria 201174|Actinobacteria Q Parallel beta-helix repeats - - - - - - - - - - - - Beta_helix,CBM_4_9,F5_F8_type_C,Laminin_G_3 k59_9772_1 1316936.K678_00420 1.03e-24 103.0 2CJW6@1|root,32SAX@2|Bacteria,1N3WF@1224|Proteobacteria,2USGV@28211|Alphaproteobacteria,2JX0G@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_9772_3 1566993.A0A0A7HER9_9CAUD 1.72e-56 203.0 4QEW8@10239|Viruses,4QTWI@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_133605_2 1041826.FCOL_05440 1.79e-37 131.0 COG0270@1|root,COG0270@2|Bacteria,4P351@976|Bacteroidetes,1I9UJ@117743|Flavobacteriia,2NZ0G@237|Flavobacterium 976|Bacteroidetes L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_375798_1 646529.Desaci_1301 7.77e-68 228.0 COG4653@1|root,COG4653@2|Bacteria,1TS6A@1239|Firmicutes,24994@186801|Clostridia,266IV@186807|Peptococcaceae 186801|Clostridia S TIGRFAM phage major capsid protein, HK97 family - - - - - - - - - - - - Phage_capsid k59_205898_1 1197951.I6R9K8_9CAUD 1.6e-86 265.0 4QFIC@10239|Viruses,4QXG2@35237|dsDNA viruses no RNA stage,4QTVA@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_190097_3 1296416.JACB01000015_gene4794 1.17e-08 57.4 COG0553@1|root,COG0553@2|Bacteria,4NG6P@976|Bacteroidetes,1HZUG@117743|Flavobacteriia,2YGIK@290174|Aquimarina 976|Bacteroidetes L SNF2 family N-terminal domain - - 2.7.11.1 ko:K08282 - - - - ko00000,ko01000 - - - Helicase_C,SNF2_N k59_278576_2 105154.Q9MBU6_9VIRU 8.28e-216 615.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_278576_3 1986029.Q9MBM7_9VIRU 1.68e-14 75.1 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_145492_1 13690.CP98_04997 1.24e-14 76.6 COG4695@1|root,COG4695@2|Bacteria,1N389@1224|Proteobacteria,2UD69@28211|Alphaproteobacteria,2K5UW@204457|Sphingomonadales 204457|Sphingomonadales S Portal protein - - - - - - - - - - - - - k59_60247_5 469604.HMPREF0946_01119 2.37e-14 72.4 2EGZP@1|root,33ART@2|Bacteria,37B5P@32066|Fusobacteria 32066|Fusobacteria S YopX protein - - - - - - - - - - - - YopX k59_36333_1 1005994.GTGU_01433 2.18e-19 95.5 COG3378@1|root,COG5545@1|root,COG3378@2|Bacteria,COG5545@2|Bacteria,1MVGK@1224|Proteobacteria,1S6W2@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Virulence-associated protein - - - ko:K06919 - - - - ko00000 - - - Prim-Pol,Toprim_3,Toprim_4,VirE k59_351812_1 1205681.CALW02000096_gene1175 3.15e-07 54.3 COG0358@1|root,COG0358@2|Bacteria,1R5JV@1224|Proteobacteria,2TW8V@28211|Alphaproteobacteria,48UK0@772|Bartonellaceae 28211|Alphaproteobacteria L Toprim domain - - - - - - - - - - - - Toprim_3 k59_351812_7 573.JG24_10890 8.24e-27 101.0 2CH99@1|root,32S5M@2|Bacteria,1N2GH@1224|Proteobacteria,1T0UT@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Recombination enhancement, RecA-dependent nuclease - - - - - - - - - - - - RecA_dep_nuc k59_351812_9 1198232.CYCME_2441 9.02e-49 160.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,460QZ@72273|Thiotrichales 72273|Thiotrichales L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_351812_12 91604.ID47_02985 4.39e-78 251.0 COG0507@1|root,COG0507@2|Bacteria,1R1AT@1224|Proteobacteria,2U1ZX@28211|Alphaproteobacteria 28211|Alphaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - - - - - - - - - - Terminase_6 k59_61467_2 1609634.A0A0C5AFV4_9VIRU 1.61e-90 288.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_219480_1 1416032.V5URT9_9CAUD 6.77e-25 104.0 4QDSD@10239|Viruses,4QVMR@35237|dsDNA viruses no RNA stage,4QSMJ@28883|Caudovirales,4QNQ9@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_49320_1 595460.RRSWK_05801 1.78e-41 141.0 2DRCN@1|root,33B89@2|Bacteria,2J3XX@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_353063_1 1096546.WYO_0174 3.11e-54 206.0 COG1467@1|root,COG5519@1|root,COG1467@2|Bacteria,COG5519@2|Bacteria,1QTGG@1224|Proteobacteria,2V9QI@28211|Alphaproteobacteria,1JY2B@119045|Methylobacteriaceae 28211|Alphaproteobacteria L DNA primase - - - - - - - - - - - - - k59_37023_7 926566.Terro_1757 1.75e-10 57.4 2FDB9@1|root,345D5@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_37023_18 192875.XP_004364110.1 5.77e-25 112.0 COG1793@1|root,2QTYC@2759|Eukaryota,38GKG@33154|Opisthokonta 33154|Opisthokonta L DNA ligase OB-like domain - - 6.5.1.1,6.5.1.6,6.5.1.7 ko:K10747 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00381,R00382,R10822,R10823 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_A_M,DNA_ligase_OB_2,zf-CCHH k59_231427_1 536227.CcarbDRAFT_2980 1.82e-26 112.0 2DQWK@1|root,3393J@2|Bacteria,1VT3Z@1239|Firmicutes,24ZUC@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_340705_1 641147.HMPREF9021_02663 6.41e-15 82.8 COG3941@1|root,COG3941@2|Bacteria,1RM44@1224|Proteobacteria,2VSWE@28216|Betaproteobacteria,2KPD6@206351|Neisseriales 206351|Neisseriales D nuclear chromosome segregation - - - - - - - - - - - - Tape_meas_lam_C k59_377402_1 1692249.A0A0K1RLN8_9CIRC 2.68e-27 110.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_219573_5 908337.HMPREF9257_0057 1.64e-09 59.3 2EK5K@1|root,33DW0@2|Bacteria,1VKGK@1239|Firmicutes,4HRYF@91061|Bacilli,27E8G@186827|Aerococcaceae 91061|Bacilli S Putative phage holin Dp-1 - - - - - - - - - - - - Phage_holin_Dp1 k59_219573_6 742733.HMPREF9469_05011 3.97e-32 116.0 2BT3T@1|root,30VXX@2|Bacteria,1U239@1239|Firmicutes,25JN1@186801|Clostridia,2232Q@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_340773_1 296587.XP_002506202.1 3.08e-26 116.0 COG0749@1|root,KOG0950@2759|Eukaryota,37SRP@33090|Viridiplantae,34JRW@3041|Chlorophyta 3041|Chlorophyta L 3'-5' exonuclease - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_pol_A,DNA_pol_A_exo1 k59_171788_1 1520935.A0A0H3UB63_9CIRC 2.51e-24 102.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_171788_2 1618247.A0A0C5IMK7_9CIRC 2.12e-09 62.4 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_232602_2 1692252.A0A0K1RL35_9CIRC 4.87e-91 279.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_147583_1 913183.E5RV17_9CAUD 5.09e-22 98.6 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales,4QNDH@10744|Podoviridae 10744|Podoviridae S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_13345_16 469617.FUAG_01977 1.38e-29 134.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,378G8@32066|Fusobacteria 32066|Fusobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,HHH_5 k59_13345_23 1123008.KB905697_gene3236 3.95e-05 55.1 COG3210@1|root,COG3210@2|Bacteria,4PPCP@976|Bacteroidetes 976|Bacteroidetes U Chaperone of endosialidase - - - - - - - - - - - - Peptidase_S74 k59_13345_24 440250.A5HL39_9CAUD 3.2e-24 119.0 4QBWF@10239|Viruses,4QZPF@35237|dsDNA viruses no RNA stage,4QRA3@28883|Caudovirales,4QNG4@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_13345_26 373994.Riv7116_4980 2.91e-15 85.1 COG0739@1|root,COG4678@1|root,COG0739@2|Bacteria,COG4678@2|Bacteria,1G3VG@1117|Cyanobacteria,1HNB1@1161|Nostocales 1117|Cyanobacteria G Muramidase (Phage lambda lysozyme) - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23,Phage_lysozyme k59_13345_33 440250.A5HL28_9CAUD 2.11e-80 273.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales,4QNDH@10744|Podoviridae 10744|Podoviridae S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_13345_34 440250.A5HL30_9CAUD 1.94e-90 298.0 4QGAG@10239|Viruses,4R0KB@35237|dsDNA viruses no RNA stage,4QUA4@28883|Caudovirales,4QNFP@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_244539_1 1692257.A0A0K1RL39_9CIRC 2.45e-05 51.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_354316_1 525246.HMPREF0058_0733 2.09e-23 110.0 COG0749@1|root,COG0749@2|Bacteria,2IG0A@201174|Actinobacteria,4D4MC@85005|Actinomycetales 201174|Actinobacteria L DNA polymerase - - - - - - - - - - - - DNA_pol_A k59_3142_1 272568.GDI3669 4.37e-111 344.0 COG1783@1|root,COG1783@2|Bacteria,1RAGC@1224|Proteobacteria,2U6JF@28211|Alphaproteobacteria,2JSIA@204441|Rhodospirillales 204441|Rhodospirillales S phage Terminase large subunit - - - - - - - - - - - - - k59_306860_1 105154.Q9MBU6_9VIRU 7.33e-106 324.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_233862_3 1122947.FR7_2541 2.1e-10 69.3 COG4675@1|root,COG4675@2|Bacteria,1UNQW@1239|Firmicutes,4H9I3@909932|Negativicutes 909932|Negativicutes S tail collar domain protein - - - - - - - - - - - - - k59_161076_5 311402.Avi_1945 7.28e-11 67.0 COG0484@1|root,COG0484@2|Bacteria,1Q5XG@1224|Proteobacteria,2UQPB@28211|Alphaproteobacteria,4BN22@82115|Rhizobiaceae 28211|Alphaproteobacteria O DnaJ molecular chaperone homology domain - - - - - - - - - - - - DnaJ k59_136456_2 1123013.AUIC01000007_gene161 1.52e-46 164.0 COG4227@1|root,COG4227@2|Bacteria 2|Bacteria L nucleotidyltransferase activity traC - - - - - - - - - - - DUF1738,Toprim_3,Toprim_4 k59_75773_1 1385658.U5KPZ6_9VIRU 1.8e-90 286.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_222060_1 1210884.HG799467_gene13131 3.37e-75 251.0 COG0553@1|root,COG0553@2|Bacteria 2|Bacteria L helicase activity - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_222060_2 1429046.RR21198_1066 2.91e-07 54.3 2CC1Y@1|root,31CU1@2|Bacteria,2HGF5@201174|Actinobacteria,4G3WZ@85025|Nocardiaceae 201174|Actinobacteria K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA - - - ko:K18955 - - - - ko00000,ko03000 - - - Whib k59_222060_3 1688.BCUN_0597 0.00016 46.6 2E0Z5@1|root,32WFJ@2|Bacteria,2IR2P@201174|Actinobacteria,4D1J7@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - k59_14239_2 665942.HMPREF1022_02898 4.91e-98 300.0 COG0863@1|root,COG0863@2|Bacteria,1PCS6@1224|Proteobacteria,42XRD@68525|delta/epsilon subdivisions,2WW4I@28221|Deltaproteobacteria,2MDD6@213115|Desulfovibrionales 28221|Deltaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_14239_6 479431.Namu_4628 2.89e-30 116.0 COG4725@1|root,COG4725@2|Bacteria,2IIR3@201174|Actinobacteria,4EVXR@85013|Frankiales 201174|Actinobacteria KT Belongs to the MT-A70-like family - - - - - - - - - - - - MT-A70 k59_14415_2 105154.Q9MBU3_9VIRU 3.11e-09 62.0 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_14415_3 1385658.U5KPZ6_9VIRU 1.46e-135 405.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_343155_1 1502724.FF80_03352 6.28e-73 247.0 COG4733@1|root,COG4733@2|Bacteria,1Q2WW@1224|Proteobacteria,2TUS9@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Phage-related protein, tail component - - - - - - - - - - - - DUF1983,Phage-tail_3 k59_343155_5 348824.LPU83_0607 5.93e-22 109.0 COG5281@1|root,COG5281@2|Bacteria,1QZ8N@1224|Proteobacteria,2UQY1@28211|Alphaproteobacteria,4BNW0@82115|Rhizobiaceae 28211|Alphaproteobacteria S Prophage tail length tape measure protein - - - - - - - - - - - - TMP_2 k59_343155_6 439375.Oant_0250 4.45e-21 89.4 2A685@1|root,30V0R@2|Bacteria,1N16F@1224|Proteobacteria,2V1R0@28211|Alphaproteobacteria,1J47R@118882|Brucellaceae 28211|Alphaproteobacteria S Phage tail tube protein, GTA-gp10 - - - - - - - - - - - - Phage_TAC_11 k59_368371_1 1385658.U5KPZ6_9VIRU 3.39e-157 461.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_368371_2 105154.Q9MBU3_9VIRU 0.000112 48.5 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_125974_1 1589297.A0A0B5H2N3_9CAUD 0.000208 42.7 4QEMD@10239|Viruses,4QUGF@28883|Caudovirales,4QNXF@10744|Podoviridae 10744|Podoviridae S AAA domain - - - - - - - - - - - - - k59_234946_1 384765.SIAM614_19891 8.77e-32 126.0 COG5362@1|root,COG5362@2|Bacteria,1R90H@1224|Proteobacteria,2U236@28211|Alphaproteobacteria 28211|Alphaproteobacteria L TIGRFAM Phage - - - - - - - - - - - - Terminase_6 k59_113399_2 525246.HMPREF0058_0736 4.61e-14 73.9 COG0553@1|root,COG0553@2|Bacteria,2IC31@201174|Actinobacteria,4D420@85005|Actinomycetales 201174|Actinobacteria KL SNF2 family N-terminal domain protein - - - - - - - - - - - - SNF2_N k59_380869_2 113395.AXAI01000002_gene5441 5.85e-21 94.4 2E4HT@1|root,32ZCW@2|Bacteria,1R6TI@1224|Proteobacteria,2VGSX@28211|Alphaproteobacteria,3JXYD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_356690_2 1510531.JQJJ01000013_gene57 1.01e-06 58.9 COG5362@1|root,COG5362@2|Bacteria,1NKZK@1224|Proteobacteria,2U0EG@28211|Alphaproteobacteria,3JXF7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6C k59_235110_1 652103.Rpdx1_2543 2.37e-13 68.9 2CHQ5@1|root,34CG1@2|Bacteria,1NJER@1224|Proteobacteria,2UYWQ@28211|Alphaproteobacteria,3K5QX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_4563_1 1692259.A0A0K1RL59_9CIRC 1.91e-10 65.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_247226_1 279238.Saro_2236 0.000933 44.3 COG4123@1|root,COG4123@2|Bacteria 2|Bacteria AJ Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) fkbM - - - - - - - - - - - Methyltransf_21 k59_320626_1 1121468.AUBR01000006_gene320 1.7e-16 81.6 2CK39@1|root,32SBG@2|Bacteria,1V8KG@1239|Firmicutes,249UQ@186801|Clostridia,42IH0@68295|Thermoanaerobacterales 186801|Clostridia S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 k59_308270_5 1079460.ATTQ01000019_gene4437 1.44e-52 189.0 2CC8M@1|root,308VJ@2|Bacteria,1R789@1224|Proteobacteria,2U2NB@28211|Alphaproteobacteria,4BHET@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_174688_1 333138.LQ50_19735 0.000864 48.1 COG0791@1|root,COG3409@1|root,COG0791@2|Bacteria,COG3409@2|Bacteria,1V5H7@1239|Firmicutes,4HA49@91061|Bacilli,1ZRDS@1386|Bacillus 91061|Bacilli M NlpC/P60 family lytE - - - - - - - - - - - NLPC_P60,PG_binding_1 k59_65363_1 105154.Q9MBU3_9VIRU 8.71e-11 61.6 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_16844_1 512565.AMIS_80850 3.1e-53 186.0 COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria,4D8N4@85008|Micromonosporales 201174|Actinobacteria L Participates in initiation and elongation during chromosome replication dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3 k59_114835_5 240302.BN982_00207 1.01e-24 115.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,4H9Z7@91061|Bacilli 91061|Bacilli L DNA polymerase - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_54326_1 1278078.G419_04865 1.37e-08 55.8 2AQ0X@1|root,31F5W@2|Bacteria,2HIIW@201174|Actinobacteria,4G466@85025|Nocardiaceae 201174|Actinobacteria K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA - - - ko:K18955 - - - - ko00000,ko03000 - - - Whib k59_151671_3 1385515.N791_11270 0.000154 42.4 COG1551@1|root,COG1551@2|Bacteria,1N6PG@1224|Proteobacteria,1SCB4@1236|Gammaproteobacteria,1X83M@135614|Xanthomonadales 135614|Xanthomonadales J Could accelerate the degradation of some genes transcripts potentially through selective RNA binding csrA - - ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 - - - ko00000,ko00001,ko03019 - - - CsrA k59_286919_1 487521.OCU_33620 1.06e-31 127.0 COG4653@1|root,COG4653@2|Bacteria,2I9AZ@201174|Actinobacteria,235SZ@1762|Mycobacteriaceae 201174|Actinobacteria S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_5995_1 1357423.S5MAP1_9CAUD 4.73e-51 179.0 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QPEB@28883|Caudovirales,4QHXI@10662|Myoviridae 10662|Myoviridae S hydrolase activity - - - - - - - - - - - - - k59_200223_4 1384066.JAGT01000001_gene1920 0.000187 50.1 COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia,3WGA1@541000|Ruminococcaceae 186801|Clostridia L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 k59_225141_2 411460.RUMTOR_01339 3.56e-51 169.0 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_225141_3 411460.RUMTOR_01342 4.77e-83 253.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_225141_5 428125.CLOLEP_01413 2.09e-33 119.0 2E2Y0@1|root,32XYV@2|Bacteria,1VD9S@1239|Firmicutes,24PK0@186801|Clostridia,3WPDR@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_153507_1 1121015.N789_08125 3.25e-54 186.0 COG2268@1|root,COG2268@2|Bacteria,1P39U@1224|Proteobacteria 1224|Proteobacteria S SPFH domain-containing protein - - - ko:K07192 ko04910,map04910 - - - ko00000,ko00001,ko03036,ko04131,ko04147 - - - Band_7 k59_288654_1 996637.SGM_5338 1.17e-21 100.0 COG0270@1|root,COG0270@2|Bacteria,2GK6Z@201174|Actinobacteria 201174|Actinobacteria L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_299699_3 1197951.I6R0Y7_9CAUD 1.34e-09 59.3 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales 28883|Caudovirales S DnaB-like helicase C terminal domain - - - - - - - - - - - - - k59_299701_1 1986029.Q9MBM8_9VIRU 8.26e-30 122.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_141228_1 1692257.A0A0K1RL48_9CIRC 7.59e-12 71.6 4QCY8@10239|Viruses,4QUMD@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_323953_1 1400524.KL370779_gene619 1.19e-16 82.4 COG0300@1|root,COG0300@2|Bacteria,1NYHT@1224|Proteobacteria,2UTXW@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short k59_274800_2 742740.HMPREF9474_02279 2.24e-51 169.0 29YRZ@1|root,30KMY@2|Bacteria,1V4Y4@1239|Firmicutes,24HPY@186801|Clostridia,221XY@1506553|Lachnoclostridium 186801|Clostridia S Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_201989_1 1172188.KB911820_gene2847 1.76e-106 327.0 COG3567@1|root,COG3567@2|Bacteria,2H48H@201174|Actinobacteria 201174|Actinobacteria S Phage portal protein, SPP1 Gp6-like - - - - - - - - - - - - Phage_prot_Gp6 k59_153672_1 1297863.APJF01000020_gene2704 6.9e-15 80.1 28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TURR@28211|Alphaproteobacteria,3JUCC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_383669_3 426117.M446_6327 5.12e-15 77.4 28JWE@1|root,2Z9M6@2|Bacteria,1R76R@1224|Proteobacteria,2U0BP@28211|Alphaproteobacteria,1JU2G@119045|Methylobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_383669_4 1232437.KL662018_gene573 2.12e-05 48.1 COG0629@1|root,COG0629@2|Bacteria,1N7Y7@1224|Proteobacteria,42VDE@68525|delta/epsilon subdivisions,2WRWY@28221|Deltaproteobacteria,2MP1J@213118|Desulfobacterales 28221|Deltaproteobacteria L Single-strand binding protein family - - - - - - - - - - - - SSB k59_383669_5 279383.Q5DN15_9CAUD 1.9e-07 54.3 4QEUP@10239|Viruses,4QZ9A@35237|dsDNA viruses no RNA stage,4QPUA@28883|Caudovirales 28883|Caudovirales S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - - k59_359520_1 1192868.CAIU01000008_gene938 2.71e-55 189.0 COG0553@1|root,COG0553@2|Bacteria,1R7CK@1224|Proteobacteria,2U228@28211|Alphaproteobacteria,43I7K@69277|Phyllobacteriaceae 28211|Alphaproteobacteria KL DEAD-like helicases superfamily - - - - - - - - - - - - Helicase_C,N6_N4_Mtase k59_359520_2 999413.HMPREF1094_02026 4.26e-40 144.0 COG0863@1|root,COG0863@2|Bacteria,1UZIN@1239|Firmicutes 1239|Firmicutes L Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase k59_43896_1 1123020.AUIE01000007_gene3217 1.9e-10 67.0 2A70H@1|root,30VVP@2|Bacteria,1NFHJ@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_153675_1 1385658.U5KPZ6_9VIRU 1.11e-47 168.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_203648_1 938278.CAJO01000051_gene805 1.35e-07 54.3 2C2JW@1|root,3316C@2|Bacteria,1VFRB@1239|Firmicutes,24R0E@186801|Clostridia 186801|Clostridia S Domain of Unknown Function (DUF1599) - - - - - - - - - - - - DUF1599 k59_142997_1 546273.VEIDISOL_00706 6.66e-39 146.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H2W4@909932|Negativicutes 909932|Negativicutes L SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_179918_1 1385658.U5KNR1_9VIRU 2.91e-29 117.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_349664_1 186617.M9M8L2_9VIRU 1.25e-28 119.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_57791_1 1347393.HG726021_gene279 9.28e-07 52.0 COG3108@1|root,COG3108@2|Bacteria,4NW30@976|Bacteroidetes,2FSX2@200643|Bacteroidia,4AR8E@815|Bacteroidaceae 976|Bacteroidetes S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k59_57791_3 1165094.RINTHH_3920 3.55e-47 169.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_57791_5 1385658.U5KPZ6_9VIRU 6.32e-41 149.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_228602_1 351016.RAZWK3B_16655 6.12e-15 80.5 COG2433@1|root,COG2433@2|Bacteria,1QZB7@1224|Proteobacteria,2USEZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Pfam Transposase IS66 - - - - - - - - - - - - - k59_143007_1 1370122.JHXQ01000023_gene3058 4.54e-23 96.3 COG3023@1|root,COG3023@2|Bacteria,1N032@1224|Proteobacteria,2U6P9@28211|Alphaproteobacteria,4BHDN@82115|Rhizobiaceae 28211|Alphaproteobacteria V N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2,PG_binding_1 k59_82290_1 384765.SIAM614_19891 9.03e-32 127.0 COG5362@1|root,COG5362@2|Bacteria,1R90H@1224|Proteobacteria,2U236@28211|Alphaproteobacteria 28211|Alphaproteobacteria L TIGRFAM Phage - - - - - - - - - - - - Terminase_6 k59_45652_1 279280.Q6J1R9_9CAUD 1.87e-57 189.0 4QH0X@10239|Viruses,4QXIJ@35237|dsDNA viruses no RNA stage,4QSY6@28883|Caudovirales,4QNTU@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_155410_2 2003327.CAPSD_BPCHP 7.07e-12 67.8 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_239705_1 866895.HBHAL_2432 1.42e-13 79.7 2EYIP@1|root,33RSF@2|Bacteria,1VSNU@1239|Firmicutes,4HUJ1@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k59_252111_1 1165094.RINTHH_3920 1.18e-68 223.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_349782_5 648885.KB316282_gene1975 1.12e-17 82.0 COG4227@1|root,COG4227@2|Bacteria,1MU8I@1224|Proteobacteria,2TRIT@28211|Alphaproteobacteria,1JTRG@119045|Methylobacteriaceae 28211|Alphaproteobacteria L Domain of unknown function (DUF1738) - - - - - - - - - - - - DUF1738,EpmC k59_82557_1 3067.XP_002955713.1 9.58e-58 200.0 COG1372@1|root,2QRRC@2759|Eukaryota 2759|Eukaryota L reductase - GO:0003674,GO:0003824,GO:0004748,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009141,GO:0009142,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - Ribonuc_red_lgC k59_373583_1 186617.M9M8L2_9VIRU 1.62e-86 273.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_303233_2 1564096.A0A0A0YS96_9CAUD 5.67e-45 169.0 4QBB8@10239|Viruses,4QQZ7@28883|Caudovirales,4QKKE@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_189705_1 1405.DJ92_144 7.88e-08 58.9 COG0739@1|root,COG3103@1|root,COG0739@2|Bacteria,COG3103@2|Bacteria,1TRWJ@1239|Firmicutes,4HWZ3@91061|Bacilli 91061|Bacilli MT peptidase - - - - - - - - - - - - Peptidase_M23,SH3_3 k59_119736_3 1437882.AZRU01000102_gene3871 5.23e-10 60.5 COG2404@1|root,COG2404@2|Bacteria,1MXEH@1224|Proteobacteria,1SADM@1236|Gammaproteobacteria,1YI8A@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S phosphoesterase DHHA1 - - - - - - - - - - - - DHHA1 k59_71887_1 156889.Mmc1_1012 1.46e-86 294.0 COG2268@1|root,COG2268@2|Bacteria,1NT13@1224|Proteobacteria,2U335@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Band 7 protein - - - - - - - - - - - - - k59_351421_4 1122243.KB903779_gene423 7.34e-14 69.7 COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,1S5VH@1236|Gammaproteobacteria,3NJ26@468|Moraxellaceae 1236|Gammaproteobacteria H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis folA GO:0000166,GO:0003674,GO:0003824,GO:0004146,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008144,GO:0008150,GO:0008152,GO:0016491,GO:0016645,GO:0016646,GO:0019842,GO:0031406,GO:0033218,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051870,GO:0051871,GO:0055114,GO:0070401,GO:0070402,GO:0072341,GO:0097159,GO:1901265,GO:1901363 1.5.1.3 ko:K00287,ko:K18590 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 br01600,ko00000,ko00001,ko00002,ko01000,ko01504 - - iECBD_1354.ECBD_3567,iECDH1ME8569_1439.ECDH1ME8569_0047,iECNA114_1301.ECNA114_0036,iEcDH1_1363.EcDH1_3551,iEcSMS35_1347.EcSMS35_0050,iG2583_1286.G2583_0050,iJN746.PP_5132,iNRG857_1313.NRG857_00250,iUMN146_1321.UM146_23020 DHFR_1 k59_157404_1 797304.Natgr_1861 8.89e-21 96.7 COG1196@1|root,arCOG00371@2157|Archaea 2157|Archaea D Required for chromosome condensation and partitioning - - 3.6.4.12 ko:K03658 - - - - ko00000,ko01000,ko03400 - - - - k59_265615_2 1122962.AULH01000018_gene337 3.8e-23 99.8 COG5281@1|root,COG5281@2|Bacteria,1QUCD@1224|Proteobacteria,2TWHW@28211|Alphaproteobacteria,371K7@31993|Methylocystaceae 28211|Alphaproteobacteria S Prophage tail length tape measure protein - - - - - - - - - - - - TMP_2 k59_108253_1 435830.HMPREF0045_00762 8.99e-05 50.8 COG0739@1|root,COG0739@2|Bacteria,2GM7Q@201174|Actinobacteria,4D81C@85005|Actinomycetales 201174|Actinobacteria M Peptidase, M23 - - - - - - - - - - - - Peptidase_M23 k59_84336_1 457429.ABJI02000074_gene5201 3.65e-07 57.4 COG3266@1|root,COG5434@1|root,COG3266@2|Bacteria,COG5434@2|Bacteria,2I2V4@201174|Actinobacteria 201174|Actinobacteria M Parallel beta-helix repeats pelX - - - - - - - - - - - Beta_helix,CBM_2,CBM_35,CBM_6 k59_362666_1 457398.HMPREF0326_03026 2.24e-47 159.0 2D1GK@1|root,32TAP@2|Bacteria,1QV4T@1224|Proteobacteria,43CXG@68525|delta/epsilon subdivisions,2X85J@28221|Deltaproteobacteria,2MFAA@213115|Desulfovibrionales 28221|Deltaproteobacteria L C-5 cytosine-specific DNA methylase - - - - - - - - - - - - - k59_314942_2 649831.L083_5995 7.6e-18 90.9 COG4653@1|root,COG4653@2|Bacteria,2HZB6@201174|Actinobacteria 201174|Actinobacteria OU capsid protein - - - - - - - - - - - - Phage_capsid k59_230534_4 743721.Psesu_1131 1.17e-22 103.0 COG5377@1|root,COG5377@2|Bacteria,1MWP8@1224|Proteobacteria,1RN9Q@1236|Gammaproteobacteria,1X5CX@135614|Xanthomonadales 135614|Xanthomonadales L COG5377 Phage-related protein - - - - - - - - - - - - YqaJ k59_230534_6 278957.ABEA03000161_gene112 5e-24 107.0 COG4422@1|root,COG4422@2|Bacteria,46Y5W@74201|Verrucomicrobia,3K8ZM@414999|Opitutae 414999|Opitutae S Protein of unknown function (DUF5131) - - - - - - - - - - - - DUF5131 k59_327534_2 1121864.OMO_01118 4.8e-06 55.8 COG0739@1|root,COG3942@1|root,COG0739@2|Bacteria,COG3942@2|Bacteria,1UNUC@1239|Firmicutes,4IUPT@91061|Bacilli,4B60K@81852|Enterococcaceae 91061|Bacilli M Peptidase family M23 - - - - - - - - - - - - CHAP,Peptidase_M23 k59_327534_5 1122947.FR7_2541 1.01e-13 77.8 COG4675@1|root,COG4675@2|Bacteria,1UNQW@1239|Firmicutes,4H9I3@909932|Negativicutes 909932|Negativicutes S tail collar domain protein - - - - - - - - - - - - - k59_181735_2 1234888.K0A2J2_9VIRU 5.51e-170 495.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_255347_2 1234888.K0A2R8_9VIRU 4.67e-55 186.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_61056_1 1249997.JHZW01000003_gene3734 3.4e-17 90.9 COG1511@1|root,COG3210@1|root,COG1511@2|Bacteria,COG3210@2|Bacteria,4PKI0@976|Bacteroidetes,1IKUE@117743|Flavobacteriia,2PI31@252356|Maribacter 976|Bacteroidetes U PFAM Collagen triple helix repeat (20 copies) - - - - - - - - - - - - - k59_364748_1 1524880.A0A076G5F5_9VIRU 2.27e-12 68.6 4QAIK@10239|Viruses 10239|Viruses S bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity - - - - - - - - - - - - - k59_291857_1 796942.HMPREF9623_00672 6.11e-12 68.2 COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24APG@186801|Clostridia 186801|Clostridia M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT k59_328369_1 1304878.AUGD01000009_gene6390 6.78e-15 70.5 2AKH8@1|root,31B97@2|Bacteria,1NYNN@1224|Proteobacteria,2UTCA@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_328369_2 1123508.JH636439_gene1604 1.51e-11 63.9 29XN2@1|root,30JDF@2|Bacteria,2J498@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_243177_5 202952.BBLI01000124_gene3974 1.5e-69 230.0 COG3843@1|root,COG3843@2|Bacteria,1QW4J@1224|Proteobacteria,1T2SH@1236|Gammaproteobacteria,3NM42@468|Moraxellaceae 1236|Gammaproteobacteria U MobA/MobL family - - - - - - - - - - - - MobA_MobL k59_194726_1 1555202.A0A097EX03_9CAUD 2.1e-06 49.3 4QHMD@10239|Viruses,4QRG7@28883|Caudovirales,4QIFJ@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_376991_1 991905.SL003B_4061 5.65e-25 107.0 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,2TQWC@28211|Alphaproteobacteria,4BRAS@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria L UvrD-like helicase C-terminal domain - - - - - - - - - - - - AAA_30,UvrD_C_2 k59_291860_1 994573.T472_0211805 5.27e-27 113.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,36M8D@31979|Clostridiaceae 186801|Clostridia L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_279845_1 1437882.AZRU01000122_gene4891 7.15e-19 90.9 COG0507@1|root,COG0507@2|Bacteria,1QFB3@1224|Proteobacteria,1TCHA@1236|Gammaproteobacteria,1YKBW@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria L PIF1-like helicase - - - - - - - - - - - - AAA_30,UvrD_C_2 k59_48971_1 1385658.U5KPZ6_9VIRU 1.54e-78 254.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_316224_3 1609634.A0A0C5AFT2_9VIRU 7.4e-112 333.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_73182_2 1121033.AUCF01000011_gene1828 2.14e-25 105.0 COG1573@1|root,COG1573@2|Bacteria 2|Bacteria L deaminated base DNA N-glycosylase activity - - - - - - - - - - - - UDG k59_206889_2 1618247.A0A0C5I2K0_9CIRC 6.34e-28 118.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_133899_4 1385658.U5KPZ6_9VIRU 3.34e-108 330.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_121795_6 1234888.K0A2R8_9VIRU 7.28e-25 106.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_267474_5 1609634.A0A0C5AFT2_9VIRU 7.96e-127 373.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_267474_7 1609634.A0A0C5AFV4_9VIRU 5.87e-230 650.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_267474_8 1609634.A0A0C5ANA6_9VIRU 7.48e-19 85.1 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_36782_2 1197477.IA57_12340 5.73e-12 66.6 2DMPB@1|root,32SV8@2|Bacteria,4NSG4@976|Bacteroidetes,1I3FJ@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_109653_1 1692244.A0A0K1RLR5_9CIRC 2.5e-19 95.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_194777_1 1618248.A0A0C5IB82_9CIRC 9.83e-79 248.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_304429_41 232721.Ajs_2386 2.25e-12 72.0 28H5T@1|root,2Z7IB@2|Bacteria,1N7V9@1224|Proteobacteria,2VJZB@28216|Betaproteobacteria,4AAJS@80864|Comamonadaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_304429_43 646529.Desaci_0624 1.05e-11 68.2 COG2227@1|root,COG2227@2|Bacteria,1V9EP@1239|Firmicutes,24ZEZ@186801|Clostridia,263SG@186807|Peptococcaceae 186801|Clostridia H PFAM Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 k59_304429_45 1123508.JH636441_gene3521 4.48e-80 256.0 COG0535@1|root,COG0535@2|Bacteria,2J3DJ@203682|Planctomycetes 203682|Planctomycetes S Iron-sulfur cluster-binding domain - - - - - - - - - - - - Radical_SAM,SPASM k59_304429_47 716928.AJQT01000109_gene1197 2.02e-34 126.0 2AM58@1|root,31BZI@2|Bacteria,1P06W@1224|Proteobacteria,2UU8Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_182728_1 1190606.AJYG01000064_gene1386 2.97e-25 118.0 COG0503@1|root,COG1040@1|root,COG0503@2|Bacteria,COG1040@2|Bacteria,1QV41@1224|Proteobacteria,1RSAP@1236|Gammaproteobacteria,1XVT9@135623|Vibrionales 135623|Vibrionales K acetyltransferase - - - - - - - - - - - - - k59_742_1 1179778.PMM47T1_24069 1.03e-05 52.8 2DPZ4@1|root,32UN5@2|Bacteria,1N6B8@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_219637_2 369723.Strop_0517 3.6e-27 111.0 2EES9@1|root,338JX@2|Bacteria,2H5MY@201174|Actinobacteria 201174|Actinobacteria L RNase_H superfamily - - - - - - - - - - - - RNase_H_2 k59_231582_1 1041142.ATTP01000043_gene5286 8.44e-60 197.0 2C22H@1|root,305QB@2|Bacteria,1RFAD@1224|Proteobacteria,2U8GY@28211|Alphaproteobacteria,4BEFE@82115|Rhizobiaceae 28211|Alphaproteobacteria S Chaperone of endosialidase - - - - - - - - - - - - Peptidase_S74 k59_170711_1 1379707.S5SXZ4_9CIRC 5.43e-15 80.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_122286_2 864069.MicloDRAFT_00064220 9.05e-42 148.0 COG0863@1|root,COG0863@2|Bacteria,1R7RR@1224|Proteobacteria,2TS8Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase k59_316594_6 46429.BV95_03014 5.56e-07 60.8 COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,2TSZY@28211|Alphaproteobacteria,2K25I@204457|Sphingomonadales 204457|Sphingomonadales E Belongs to the Glu Leu Phe Val dehydrogenases family - - 1.4.1.3,1.4.1.4 ko:K00261,ko:K00262 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 M00740 R00243,R00248 RC00006,RC02799 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ELFV_dehydrog,ELFV_dehydrog_N k59_293086_4 1280944.HY17_04455 7.49e-14 75.9 2EN65@1|root,33FU2@2|Bacteria,1NF56@1224|Proteobacteria,2UHK8@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_147343_1 755178.Cyan10605_3427 1.92e-12 76.3 COG1674@1|root,COG1674@2|Bacteria,1G2BT@1117|Cyanobacteria 1117|Cyanobacteria D DNA segregation ATPase FtsK SpoIIIE - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - DNA_pol_A_exo1,FtsK_SpoIIIE,PDDEXK_1 k59_293187_1 186617.M9M8L2_9VIRU 9.48e-90 283.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_293187_3 1385658.U5KNR1_9VIRU 3.95e-78 248.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_293187_9 105154.Q9MBU6_9VIRU 8.71e-85 267.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_74512_4 1234888.K0A2J2_9VIRU 1.74e-106 333.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_329624_1 105425.BBPL01000002_gene6422 7.34e-14 78.2 COG1749@1|root,COG1749@2|Bacteria,2I2X3@201174|Actinobacteria,2NG74@228398|Streptacidiphilus 201174|Actinobacteria N Mo-co oxidoreductase dimerisation domain - - - - - - - - - - - - Big_5,DUF4082,Mo-co_dimer,fn3 k59_232283_2 1122927.KB895423_gene3757 6.4e-58 225.0 COG3420@1|root,COG4099@1|root,COG5492@1|root,COG3420@2|Bacteria,COG4099@2|Bacteria,COG5492@2|Bacteria,1VR20@1239|Firmicutes,4HVGA@91061|Bacilli,26V79@186822|Paenibacillaceae 91061|Bacilli P Right handed beta helix region - - - - - - - - - - - - Beta_helix,Big_2 k59_159531_2 645099.MREP_BBTVA 5.86e-12 70.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_365765_3 1609634.A0A0C5AFV4_9VIRU 1.84e-212 607.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_1518_2 1121100.JCM6294_593 0.000265 51.6 COG3378@1|root,COG3378@2|Bacteria,4NG1J@976|Bacteroidetes,2FQRK@200643|Bacteroidia,4AQ5P@815|Bacteroidaceae 976|Bacteroidetes S Phage plasmid primase, P4 family domain protein - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5 k59_123097_1 880070.Cycma_0727 3.91e-05 56.2 COG3055@1|root,COG3055@2|Bacteria,4NHHD@976|Bacteroidetes,47K9E@768503|Cytophagia 976|Bacteroidetes S Kelch repeat - - - - - - - - - - - - He_PIG,Kelch_1,Kelch_4,Kelch_6,Malectin,PKD k59_183266_3 136084.Q9G0H1_9CAUD 7.29e-44 164.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_124379_2 691965.D4P7D6_9CAUD 1.62e-32 134.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_136180_3 701347.Entcl_1861 3.22e-32 120.0 COG3926@1|root,COG3926@2|Bacteria,1QV3R@1224|Proteobacteria,1T276@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Glycosyl hydrolase 108 - - - - - - - - - - - - CHAP k59_342669_1 1385658.U5KPZ6_9VIRU 4.47e-103 323.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_245349_3 1788447.A0A190WHJ9_9CIRC 3.96e-23 102.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_233391_1 5011.R4XK29 0.000493 50.8 COG2272@1|root,KOG1516@2759|Eukaryota,38EQ2@33154|Opisthokonta,3NX7C@4751|Fungi,3QR31@4890|Ascomycota,3MDFA@451866|Taphrinomycotina 4751|Fungi I Carboxylesterase family - GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0052689 - - - - - - - - - - COesterase,DnaJ,zf-CSL k59_269679_2 1206731.BAGB01000013_gene2363 2.74e-75 244.0 COG0438@1|root,COG0438@2|Bacteria,2HPJ5@201174|Actinobacteria,4G5MD@85025|Nocardiaceae 201174|Actinobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 k59_269679_19 1051985.l11_02320 4.13e-08 61.6 COG0863@1|root,COG0863@2|Bacteria,1MY4G@1224|Proteobacteria,2VQD7@28216|Betaproteobacteria,2KT8D@206351|Neisseriales 206351|Neisseriales H DNA methylase - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_269679_20 269799.Gmet_3140 1.08e-49 181.0 COG0338@1|root,COG3392@1|root,COG0338@2|Bacteria,COG3392@2|Bacteria,1P85S@1224|Proteobacteria 1224|Proteobacteria L site-specific DNA-methyltransferase (Adenine-specific) dam GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006281,GO:0006298,GO:0006304,GO:0006305,GO:0006306,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007049,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009007,GO:0009008,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0022402,GO:0032259,GO:0032775,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043412,GO:0043414,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044728,GO:0044786,GO:0044787,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901576,GO:1901681,GO:1902292,GO:1902328,GO:1904047 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_269679_21 421531.IX38_01905 3.22e-42 145.0 COG2856@1|root,COG2856@2|Bacteria,4NNFC@976|Bacteroidetes,1I29G@117743|Flavobacteriia,3ZRW9@59732|Chryseobacterium 976|Bacteroidetes E Macro domain - - - - - - - - - - - - Macro k59_269679_25 1304872.JAGC01000009_gene896 2.83e-70 238.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2WJCA@28221|Deltaproteobacteria,2M7ZB@213115|Desulfovibrionales 28221|Deltaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_87718_1 237368.SCABRO_02180 2.3e-18 89.0 2DBHN@1|root,2Z9BF@2|Bacteria,2J15J@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_197153_1 1144310.PMI07_002369 1.52e-23 108.0 28QU5@1|root,2ZD9H@2|Bacteria,1RAU8@1224|Proteobacteria,2U2GD@28211|Alphaproteobacteria,4BC6R@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_197153_2 358220.C380_10860 3.87e-17 80.1 COG1670@1|root,COG1670@2|Bacteria,1ND46@1224|Proteobacteria,2W4JU@28216|Betaproteobacteria 28216|Betaproteobacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - - - - - - - - - - - k59_197153_3 716928.AJQT01000006_gene2763 0.000159 51.2 2C22H@1|root,305QB@2|Bacteria,1RFAD@1224|Proteobacteria,2U8GY@28211|Alphaproteobacteria,4BEFE@82115|Rhizobiaceae 28211|Alphaproteobacteria S Chaperone of endosialidase - - - - - - - - - - - - Peptidase_S74 k59_245439_2 290397.Adeh_2610 4e-22 93.6 COG0615@1|root,COG0615@2|Bacteria,1REW3@1224|Proteobacteria,42SGQ@68525|delta/epsilon subdivisions,2WPTP@28221|Deltaproteobacteria 28221|Deltaproteobacteria H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose rfaE - - - - - - - - - - - CTP_transf_like k59_245439_3 1244869.H261_07973 1.89e-60 206.0 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1R7DJ@1224|Proteobacteria,2VF2S@28211|Alphaproteobacteria,2JT8E@204441|Rhodospirillales 204441|Rhodospirillales IM Cytidylyltransferase-like - - - - - - - - - - - - CTP_transf_like,PfkB k59_245439_4 697282.Mettu_1302 4.89e-115 345.0 COG0535@1|root,COG0535@2|Bacteria,1PHAQ@1224|Proteobacteria 1224|Proteobacteria C Radical SAM - - - - - - - - - - - - Fer4_14,Radical_SAM,SPASM k59_245439_5 796945.HMPREF1145_1163 5.87e-17 85.5 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,248Z9@186801|Clostridia,2PRMG@265975|Oribacterium 186801|Clostridia EH Belongs to the TPP enzyme family - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k59_245439_6 313628.LNTAR_03149 7.5e-83 271.0 COG0028@1|root,COG0028@2|Bacteria 2|Bacteria EH Belongs to the TPP enzyme family ilvB2 - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k59_245439_8 1210884.HG799466_gene12604 9.91e-33 125.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Aminotran_5,Methyltransf_11,Methyltransf_25 k59_137074_1 105154.Q9MBU6_9VIRU 8.19e-39 143.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_137074_8 1986029.Q9MBM3_9VIRU 9.28e-56 190.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_137074_10 1609634.A0A0C5AFV4_9VIRU 2.56e-28 113.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_355983_1 145579.B_BPPHM 3.78e-17 80.9 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_258740_8 492774.JQMB01000013_gene3024 4.84e-22 110.0 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,2TVGJ@28211|Alphaproteobacteria,4BH6J@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_258740_12 520999.PROVALCAL_01874 4.02e-05 56.2 28HCK@1|root,2Z7PE@2|Bacteria,1NK7S@1224|Proteobacteria,1S03Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_198150_2 1609634.A0A0C5ANA6_9VIRU 4.43e-20 88.6 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_380381_1 1379715.S5TMW6_9CIRC 2.76e-60 201.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_234568_5 269482.Bcep1808_3260 1.63e-20 89.4 COG0817@1|root,COG0817@2|Bacteria,1RCYK@1224|Proteobacteria,2VHSV@28216|Betaproteobacteria,1K7IT@119060|Burkholderiaceae 28216|Betaproteobacteria L 16.7 kDa protein gp11 SWALL Q9JMN0 (EMBL AB036666) (151 aa) fasta scores E() 1.7e-13, 36.61 id in 142 aa, and to Ralstonia solanacearum bacteriophage-related protein rsc3228 or rs02445 SWALL Q8XUG0 (EMBL AL646074) (154 aa) fasta scores E() 1.1e-21, 46.35 id in 151 aa - - - - - - - - - - - - - k59_222878_1 186617.M9M8L2_9VIRU 5.89e-65 214.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_184788_1 145579.REP_BPPHM 0.000101 51.2 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_64845_3 1121859.KB890757_gene1742 1.57e-07 62.0 COG0018@1|root,COG0018@2|Bacteria 2|Bacteria J arginyl-tRNA aminoacylation argS - 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d k59_64845_5 1469557.JSWF01000033_gene1579 7.98e-06 57.8 COG1520@1|root,COG2931@1|root,COG5295@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,COG5295@2|Bacteria,4PNC3@976|Bacteroidetes,1IKGU@117743|Flavobacteriia 976|Bacteroidetes UW Hep Hag repeat protein - - - - - - - - - - - - - k59_369137_3 1609634.A0A0C5AFV4_9VIRU 3.49e-167 491.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_296663_1 234267.Acid_1347 3.06e-20 97.4 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,3Y3X3@57723|Acidobacteria 57723|Acidobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_90288_1 1121948.AUAC01000005_gene2072 0.000148 49.7 COG0582@1|root,COG0582@2|Bacteria,1N2H9@1224|Proteobacteria,2TS7K@28211|Alphaproteobacteria,43Z3M@69657|Hyphomonadaceae 28211|Alphaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase k59_333246_1 1609634.A0A0C5AFV4_9VIRU 2.01e-194 555.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_285925_2 485916.Dtox_1542 1.67e-21 93.2 COG2856@1|root,COG3093@1|root,COG2856@2|Bacteria,COG3093@2|Bacteria,1V0AU@1239|Firmicutes,24BH5@186801|Clostridia 186801|Clostridia K Addiction module antidote protein, HigA higA - - ko:K18831 - - - - ko00000,ko02048,ko03000 - - - HTH_3,Peptidase_M78 k59_381604_4 1636271.A0A0E3JI89_9CAUD 9.29e-20 88.6 4QH9H@10239|Viruses,4QTW5@28883|Caudovirales,4QN1C@10699|Siphoviridae 10699|Siphoviridae S kinase activity - - - - - - - - - - - - - k59_185587_1 1089548.KI783301_gene2630 6.33e-66 223.0 COG0553@1|root,COG0553@2|Bacteria,1TP2C@1239|Firmicutes,4HTYH@91061|Bacilli 91061|Bacilli KL DEAD-like helicases superfamily - - - - - - - - - - - - - k59_259860_3 644107.SL1157_1635 2.64e-41 154.0 COG2404@1|root,COG2404@2|Bacteria,1PKY9@1224|Proteobacteria,2V2FR@28211|Alphaproteobacteria,4NDK2@97050|Ruegeria 28211|Alphaproteobacteria S hydrolase activity, acting on ester bonds - - - - - - - - - - - - - k59_102539_1 1121930.AQXG01000001_gene1278 2.66e-08 57.4 COG1403@1|root,COG1403@2|Bacteria,4NJ0T@976|Bacteroidetes 976|Bacteroidetes L HNH endonuclease - - - - - - - - - - - - HNH,HNH_5 k59_5414_2 1165094.RINTHH_3920 2.42e-61 203.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_138809_4 575540.Isop_2425 3.47e-26 111.0 COG5283@1|root,COG5283@2|Bacteria,2J1F5@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_260073_1 1692256.A0A0K1RL85_9CIRC 2.37e-70 227.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_358477_1 215803.DB30_7549 2.04e-13 73.2 COG0863@1|root,COG4123@1|root,COG0863@2|Bacteria,COG4123@2|Bacteria,1NXST@1224|Proteobacteria,43BMK@68525|delta/epsilon subdivisions,2WTFK@28221|Deltaproteobacteria,2Z33Q@29|Myxococcales 28221|Deltaproteobacteria L DNA methylase - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_67376_1 1385658.U5KPZ6_9VIRU 2.15e-62 208.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_236852_2 1385658.U5KPZ6_9VIRU 2.38e-143 430.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_236852_4 105154.Q9MBU0_9VIRU 3.71e-47 167.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_200924_7 440512.C211_04145 1.23e-55 184.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,1SQ0T@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_200924_13 160492.XF_1762 1.75e-42 145.0 2C5J1@1|root,3067M@2|Bacteria,1N4SF@1224|Proteobacteria,1TCN1@1236|Gammaproteobacteria,1XA5Q@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k59_200924_18 1054217.TALC_00932 0.000441 42.7 arCOG06550@1|root,arCOG06550@2157|Archaea 2157|Archaea S Domain of unknown function (DUF1508) - - - ko:K09946 - - - - ko00000 - - - DUF1508 k59_200924_21 352165.HMPREF7215_0555 5.18e-20 97.1 COG1573@1|root,COG1573@2|Bacteria,3TAS8@508458|Synergistetes 508458|Synergistetes L uracil-DNA glycosylase - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_200924_29 156889.Mmc1_1722 1.6e-10 70.5 COG4675@1|root,COG4675@2|Bacteria,1Q34D@1224|Proteobacteria,2UJKF@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Membrane - - - - - - - - - - - - - k59_384186_1 1692249.A0A0K1RLN8_9CIRC 1.01e-34 132.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_93894_2 716928.AJQT01000109_gene1178 5.8e-36 138.0 COG0553@1|root,COG0553@2|Bacteria,1R7CK@1224|Proteobacteria,2U228@28211|Alphaproteobacteria,4BN0G@82115|Rhizobiaceae 28211|Alphaproteobacteria KL DNA methylase N-4 - - - - - - - - - - - - Helicase_C,N6_N4_Mtase k59_372219_2 105154.Q9MBU0_9VIRU 1.38e-25 111.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_32752_3 1385658.U5KPZ6_9VIRU 3.5e-49 172.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_324481_1 105154.Q9MBU6_9VIRU 6.61e-67 221.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_187562_1 1609634.A0A0C5AFT2_9VIRU 2.31e-67 217.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_312017_1 1283076.M1IP93_9CAUD 1.35e-33 135.0 4QAZ6@10239|Viruses,4QUU8@35237|dsDNA viruses no RNA stage,4QPHV@28883|Caudovirales,4QI4H@10662|Myoviridae 10662|Myoviridae S Phage tail sheath protein - GO:0005575,GO:0019012,GO:0044423,GO:0098015,GO:0098027 - - - - - - - - - - - k59_227351_2 1123487.KB892865_gene1401 5.2e-33 119.0 2CIC0@1|root,2ZUFF@2|Bacteria,1PB71@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_93896_2 945083.W0LM09_9CAUD 1.39e-82 261.0 4QAIJ@10239|Viruses,4QVZ9@35237|dsDNA viruses no RNA stage,4QPXI@28883|Caudovirales,4QM02@10699|Siphoviridae 10699|Siphoviridae S C-5 cytosine-specific DNA methylase - - - - - - - - - - - - - k59_250986_2 457405.FSDG_01548 4.12e-15 71.6 2EC8I@1|root,33670@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_202532_2 1121943.KB900008_gene1987 2.39e-43 172.0 2DZHM@1|root,32VAY@2|Bacteria,1N0DC@1224|Proteobacteria,1SP9I@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_202532_5 1201292.DR75_1631 1.51e-05 57.4 COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HGP4@91061|Bacilli,4B1AH@81852|Enterococcaceae 91061|Bacilli S Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_262749_3 1572715.A0A0A7TY81_9CAUD 8.67e-27 104.0 4QAZT@10239|Viruses,4QPTR@28883|Caudovirales,4QKZT@10699|Siphoviridae 10699|Siphoviridae S D-alanyl-D-alanine carboxypeptidase - GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016032,GO:0016787,GO:0019048,GO:0019058,GO:0019076,GO:0019538,GO:0031640,GO:0035821,GO:0035890,GO:0035891,GO:0039633,GO:0040011,GO:0043170,GO:0044003,GO:0044004,GO:0044238,GO:0044364,GO:0044403,GO:0044419,GO:0044659,GO:0044661,GO:0051701,GO:0051704,GO:0051817,GO:0051818,GO:0051883,GO:0052126,GO:0052192,GO:0071704,GO:0140096,GO:1901564 - - - - - - - - - - - k59_262749_10 1562701.BBOF01000006_gene71 9.05e-24 99.0 2D0K9@1|root,32T8S@2|Bacteria,1MZRW@1224|Proteobacteria,2VW7X@28216|Betaproteobacteria,1KE19@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_262749_11 716544.wcw_0671 5.42e-143 428.0 COG4626@1|root,COG4626@2|Bacteria 2|Bacteria S Terminase - - - - - - - - - - - - Terminase_1 k59_262749_12 1498011.A0A096XUS7_9CAUD 5.01e-12 70.1 4QAUF@10239|Viruses,4QQIV@28883|Caudovirales,4QNZ6@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_141766_3 935948.KE386494_gene364 1.05e-05 45.1 COG1476@1|root,COG1476@2|Bacteria 2|Bacteria K sequence-specific DNA binding ansR1 - - - - - - - - - - - HTH_19,HTH_3 k59_187694_1 1108045.GORHZ_182_00100 3.96e-22 102.0 COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4GAV6@85026|Gordoniaceae 201174|Actinobacteria L ATP dependent DNA ligase C terminal region ligD GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 - R00381,R00382,R10822,R10823 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_ligase_A_C,DNA_ligase_A_M,LigD_N k59_44591_4 270673.Q6PVM5_9CAUD 1.05e-24 97.4 4QGQX@10239|Viruses,4QQ2D@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_131658_2 2003327.CAPSD_BPCHP 1.7e-163 484.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_70612_2 1443125.Z962_07515 8.65e-10 63.9 COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,36F0S@31979|Clostridiaceae 186801|Clostridia L Belongs to the 'phage' integrase family - - - - - - - - - - - - Integrase_DNA,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase k59_276728_6 1279038.KB907345_gene3489 3.88e-20 103.0 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,2TVGJ@28211|Alphaproteobacteria,2JPR0@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_240339_2 768710.DesyoDRAFT_5152 4.72e-06 52.0 2DT4K@1|root,33INK@2|Bacteria,1VQEE@1239|Firmicutes,253M4@186801|Clostridia 1239|Firmicutes - - - - - - - - - - - - - - - k59_143616_2 1692257.A0A0K1RL39_9CIRC 2.94e-28 110.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_95906_1 391616.OA238_c32910 1.68e-08 57.0 COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,2TVB3@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage tail sheath protein - - - ko:K06907 - - - - ko00000 - - - Cadherin_3,Phage_sheath_1,Phage_sheath_1C k59_361452_2 68170.KL590489_gene10310 1.33e-09 65.9 COG0175@1|root,COG0175@2|Bacteria,2H2EJ@201174|Actinobacteria,4E8K6@85010|Pseudonocardiales 201174|Actinobacteria EH Phosphoadenosine phosphosulfate reductase family - - - - - - - - - - - - PAPS_reduct k59_290865_1 691965.D4P7C5_9CAUD 1.82e-67 221.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_290865_2 691965.D4P7D3_9CAUD 3.18e-146 431.0 4QAYV@10239|Viruses,4QUZ7@35237|dsDNA viruses no RNA stage,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - k59_290865_4 691965.D4P7D6_9CAUD 2.26e-47 172.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_373967_1 1279015.KB908456_gene1597 4.81e-06 53.9 COG5301@1|root,COG5301@2|Bacteria,1N4KH@1224|Proteobacteria,1RXZU@1236|Gammaproteobacteria,1Y5J9@135624|Aeromonadales 135624|Aeromonadales S Phage tail-collar fibre protein - - - - - - - - - - - - DUF3751 k59_326345_4 105154.Q9MBU6_9VIRU 3.56e-14 73.9 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_156070_1 589865.DaAHT2_1274 3.09e-06 55.8 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2WIPR@28221|Deltaproteobacteria,2MI69@213118|Desulfobacterales 28221|Deltaproteobacteria D DNA segregation ATPase, FtsK SpoIIIE family ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k59_276901_2 1121445.ATUZ01000011_gene460 5.48e-19 84.7 COG3023@1|root,COG3023@2|Bacteria,1N032@1224|Proteobacteria,432MJ@68525|delta/epsilon subdivisions,2WX9X@28221|Deltaproteobacteria,2MCUI@213115|Desulfovibrionales 28221|Deltaproteobacteria V PFAM N-acetylmuramoyl-L-alanine amidase family 2 - - - - - - - - - - - - Amidase_2 k59_350174_1 398578.Daci_0606 1.45e-23 105.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2VJIY@28216|Betaproteobacteria,4AD77@80864|Comamonadaceae 28216|Betaproteobacteria E Belongs to the DegT DnrJ EryC1 family vioA - 2.6.1.33 ko:K20429 - - R02773 RC00006,RC00781 ko00000,ko01000 - - - DegT_DnrJ_EryC1 k59_241883_3 1609634.A0A0C5AFT2_9VIRU 1.22e-46 166.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_265830_1 1232449.BAHV02000018_gene1544 5.69e-35 134.0 COG3598@1|root,COG3598@2|Bacteria,1TP5Q@1239|Firmicutes,24A4I@186801|Clostridia,26AUC@186813|unclassified Clostridiales 186801|Clostridia L Primase C terminal 2 (PriCT-2) - - - ko:K07505 - - - - ko00000 - - - AAA_25,PriCT_2 k59_265830_2 397291.C804_06560 2.72e-35 132.0 COG0286@1|root,COG0286@2|Bacteria,1V4NI@1239|Firmicutes,24HNX@186801|Clostridia,27NAJ@186928|unclassified Lachnospiraceae 186801|Clostridia V N-6 DNA Methylase - - - - - - - - - - - - N6_Mtase k59_205711_2 105154.Q9MBU3_9VIRU 1.81e-07 54.7 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_145271_1 1229276.DI53_1604 0.000112 48.5 COG0847@1|root,COG0847@2|Bacteria,4NPNG@976|Bacteroidetes 976|Bacteroidetes L Exonuclease - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k59_72334_1 188626.HMPREF0321_0116 8.36e-30 112.0 COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,1ZW3Y@145357|Dermacoccaceae 201174|Actinobacteria F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase k59_327754_2 1235689.K4NYY6_9CAUD 2.56e-18 83.2 4QGFZ@10239|Viruses,4QVJ7@35237|dsDNA viruses no RNA stage,4QU5D@28883|Caudovirales,4QNJN@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_22129_2 1429767.W6ARM9_9CAUD 2.97e-121 368.0 4QGGR@10239|Viruses,4QZHR@35237|dsDNA viruses no RNA stage,4QUGZ@28883|Caudovirales,4QNY3@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_327811_1 1609634.A0A0C5AFV4_9VIRU 1.7e-20 97.1 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_157737_1 1788439.A0A190WHD0_9CIRC 5.32e-27 108.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_328128_1 1463858.JOHR01000028_gene23 1.08e-16 87.8 29M5Z@1|root,3083E@2|Bacteria,2IKVT@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_60839_1 314345.SPV1_06324 4.53e-95 305.0 COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria 1224|Proteobacteria L Subunit R is required for both nuclease and ATPase activities, but not for modification - - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - DUF3387,HSDR_N,ResIII k59_72954_1 445685.E3SKI9_9CAUD 1.58e-61 201.0 4QAR1@10239|Viruses,4QUNA@35237|dsDNA viruses no RNA stage,4QPJE@28883|Caudovirales,4QI9Y@10662|Myoviridae 10662|Myoviridae S ATPase family associated with various cellular activities (AAA) - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039686,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_158034_1 1379717.S5SY19_9CIRC 7.14e-14 78.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_36540_1 1609634.A0A0C5AFV4_9VIRU 5.74e-76 246.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_243098_1 1385658.U5KPZ6_9VIRU 2.42e-44 159.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_194489_1 1197951.I6S2A3_9CAUD 2.26e-15 75.5 4QAIV@10239|Viruses,4QYFZ@35237|dsDNA viruses no RNA stage,4QQUY@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_194489_3 1220601.L7TML5_9CAUD 1.61e-52 175.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - GO:0005575,GO:0018995,GO:0019012,GO:0030430,GO:0033643,GO:0033646,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044423,GO:0046729 - - - - - - - - - - - k59_12234_1 76636.JOEC01000011_gene1730 1.23e-40 143.0 29M5Z@1|root,3083E@2|Bacteria,2IKVT@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_133741_2 1692255.A0A0K1RL52_9CIRC 1.42e-62 207.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_97258_7 411468.CLOSCI_00917 2.3e-24 96.3 2A2ID@1|root,30QVY@2|Bacteria,1V4BJ@1239|Firmicutes,24JG2@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_97258_11 478749.BRYFOR_08565 8.92e-67 218.0 2A0KC@1|root,2ZGJK@2|Bacteria,1V2JS@1239|Firmicutes,24H6R@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_97258_14 691965.D4P7I3_9CAUD 0.0 1466.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_97258_15 691965.D4P7I8_9CAUD 5.32e-45 153.0 4QGJH@10239|Viruses,4QZ35@35237|dsDNA viruses no RNA stage,4QRZS@28883|Caudovirales,4QMAA@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_182368_1 556269.ACDQ01000002_gene1166 8.52e-27 104.0 2CC49@1|root,2ZBQQ@2|Bacteria,1RA92@1224|Proteobacteria,2VYII@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF1367) - - - - - - - - - - - - DUF1367 k59_243120_1 105154.Q9MBU6_9VIRU 7.16e-60 200.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_61214_1 1234888.K0A2J2_9VIRU 6.08e-57 195.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_340501_2 1510531.JQJJ01000011_gene2910 1.69e-64 214.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,2U0EG@28211|Alphaproteobacteria,3JXF7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6C k59_352852_1 1122197.ATWI01000011_gene460 1.99e-67 223.0 COG0433@1|root,COG0433@2|Bacteria,1QTVP@1224|Proteobacteria,1T1IQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_146228_2 420324.KI912045_gene4255 1.38e-21 92.4 COG3409@1|root,COG3409@2|Bacteria,1RAYU@1224|Proteobacteria,2U6D1@28211|Alphaproteobacteria 28211|Alphaproteobacteria M N-acetylmuramidase - - - - - - - - - - - - Muraidase,PG_binding_1 k59_49105_1 765910.MARPU_09550 4.8e-34 143.0 COG4653@1|root,COG4653@2|Bacteria,1MWMB@1224|Proteobacteria,1S4MJ@1236|Gammaproteobacteria,1X0RU@135613|Chromatiales 135613|Chromatiales S Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_49105_11 1177928.TH2_05253 4.45e-27 123.0 COG1511@1|root,COG3941@1|root,COG1511@2|Bacteria,COG3941@2|Bacteria 2|Bacteria O tape measure - - - - - - - - - - - - DUF4175,TMP_2,Tape_meas_lam_C k59_36894_2 479433.Caci_7875 3.87e-33 129.0 COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria 201174|Actinobacteria S Belongs to the peptidase M16 family pepR GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Peptidase_M16,Peptidase_M16_C k59_109756_1 1609634.A0A0C5AFV4_9VIRU 6.33e-107 325.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_328534_2 105154.Q9MBU3_9VIRU 0.000171 47.8 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_328539_1 1352941.M877_26035 7.02e-19 89.0 COG4122@1|root,COG4122@2|Bacteria,2IARG@201174|Actinobacteria 201174|Actinobacteria S Macrocin-O-methyltransferase (TylF) - - - - - - - - - - - - TylF k59_12850_1 1197951.I6S2A9_9CAUD 7.79e-11 65.5 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales 28883|Caudovirales S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_182960_2 1117647.M5M_11930 5.19e-05 56.2 COG2304@1|root,COG2304@2|Bacteria,1PDQV@1224|Proteobacteria,1RPGD@1236|Gammaproteobacteria,1J904@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V Integrin alpha (beta-propellor repeats). - - - - - - - - - - - - DUF5011,FG-GAP_2 k59_219971_5 202956.BBNL01000066_gene214 4.11e-05 50.1 2D784@1|root,32TNH@2|Bacteria,1N098@1224|Proteobacteria,1SDM3@1236|Gammaproteobacteria,3NNDQ@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_171103_2 1182590.BN5_01287 3.65e-16 84.3 COG1196@1|root,COG1196@2|Bacteria 2|Bacteria D nuclear chromosome segregation - - - - - - - - - - - - Methyltransf_21 k59_110426_1 883078.HMPREF9695_01926 1.68e-30 114.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2U5BZ@28211|Alphaproteobacteria,3JRSD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_317014_1 760011.Spico_1344 8.59e-16 82.4 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2J5FM@203691|Spirochaetes 203691|Spirochaetes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_159111_1 1609634.A0A0C5AFV4_9VIRU 2.92e-45 169.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_329157_1 1609634.A0A0C5AFV4_9VIRU 7.06e-77 245.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_49760_2 1385512.N784_10825 4.54e-09 67.4 COG0210@1|root,COG0210@2|Bacteria,1TPVG@1239|Firmicutes,4HBVF@91061|Bacilli,2YBGW@289201|Pontibacillus 91061|Bacilli L Cold-inducible protein YdjO yjcD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C,YdjO k59_256191_1 1280944.HY17_04665 1.45e-16 77.4 2FI5T@1|root,349YH@2|Bacteria,1P1M3@1224|Proteobacteria,2UVNQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_256191_2 272568.GDI3673 4e-41 145.0 2DVPY@1|root,33WQ8@2|Bacteria,1N9VQ@1224|Proteobacteria,2UIC5@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_353602_1 1121413.JMKT01000011_gene2344 1.11e-42 150.0 2D1GK@1|root,32TAP@2|Bacteria,1QV4T@1224|Proteobacteria,43CXG@68525|delta/epsilon subdivisions,2X85J@28221|Deltaproteobacteria,2MFAA@213115|Desulfovibrionales 28221|Deltaproteobacteria L C-5 cytosine-specific DNA methylase - - - - - - - - - - - - - k59_207782_1 1519439.JPJG01000060_gene1885 7.55e-17 85.9 COG1783@1|root,COG4373@1|root,COG1783@2|Bacteria,COG4373@2|Bacteria,1TU2Y@1239|Firmicutes,25MM3@186801|Clostridia,2N7J6@216572|Oscillospiraceae 186801|Clostridia S phage Terminase large subunit - - - - - - - - - - - - Terminase_3 k59_110429_1 1114964.L485_00945 7.97e-15 84.7 COG0507@1|root,COG0507@2|Bacteria,1R1AT@1224|Proteobacteria,2U1ZX@28211|Alphaproteobacteria 28211|Alphaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - - - - - - - - - - Terminase_6 k59_280906_1 1609634.A0A0C5AFV4_9VIRU 1.79e-40 155.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_50654_2 1223542.GM1_041_00390 3.92e-24 105.0 COG1074@1|root,COG1074@2|Bacteria,2ICR2@201174|Actinobacteria,4GG6F@85026|Gordoniaceae 201174|Actinobacteria L PDDEXK-like domain of unknown function (DUF3799) - - - - - - - - - - - - DUF3799 k59_2031_1 745310.G432_05020 4.76e-54 176.0 2DS48@1|root,33EFF@2|Bacteria,1NQPI@1224|Proteobacteria,2UNN0@28211|Alphaproteobacteria,2KAYT@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - k59_147812_1 411460.RUMTOR_02029 7.21e-06 50.1 2A0KC@1|root,2ZGJK@2|Bacteria,1V2JS@1239|Firmicutes,24H6R@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_147812_2 691965.D4P7H8_9CAUD 6.18e-26 105.0 4QG1E@10239|Viruses,4QZE1@35237|dsDNA viruses no RNA stage,4QU6Q@28883|Caudovirales,4QMKH@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_86994_1 983544.Lacal_0120 9.09e-16 80.9 COG1215@1|root,COG1215@2|Bacteria,4NNGJ@976|Bacteroidetes,1I23Y@117743|Flavobacteriia 976|Bacteroidetes M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 k59_160170_1 1316739.R4JMZ6_9CAUD 6.27e-48 166.0 4QARC@10239|Viruses,4QV4E@35237|dsDNA viruses no RNA stage,4QPDS@28883|Caudovirales,4QP0H@10744|Podoviridae 10744|Podoviridae S nucleic acid binding - - - - - - - - - - - - - k59_330276_1 161156.JQKW01000013_gene162 1.63e-07 62.0 COG0305@1|root,COG0305@2|Bacteria,2GHHR@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria L Participates in initiation and elongation during chromosome replication - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_221020_1 1040987.AZUY01000009_gene1189 5.84e-28 105.0 2FEUE@1|root,346TC@2|Bacteria,1MZPB@1224|Proteobacteria,2UC4Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_135543_5 691965.D4P7I3_9CAUD 0.0 1325.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_366290_1 485914.Hmuk_0450 8.07e-06 50.8 COG0270@1|root,arCOG04157@2157|Archaea,2XTVW@28890|Euryarchaeota,23WH4@183963|Halobacteria 183963|Halobacteria L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_366290_2 1300350.DSW25_03715 0.000166 45.4 COG1396@1|root,COG1396@2|Bacteria,1RDBW@1224|Proteobacteria,2U7CY@28211|Alphaproteobacteria,3ZXJV@60136|Sulfitobacter 28211|Alphaproteobacteria K Helix-turn-helix - - - - - - - - - - - - HTH_19,HTH_3 k59_221191_1 1609634.A0A0C5AFV4_9VIRU 5.99e-48 170.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_342335_1 279383.Q5DN77_9CAUD 0.000424 48.5 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_293808_1 767434.Fraau_1474 1.17e-09 58.2 2DU37@1|root,33NS1@2|Bacteria,1N9FE@1224|Proteobacteria,1TM3Q@1236|Gammaproteobacteria,1X8XY@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF1364) - - - - - - - - - - - - DUF1364 k59_293808_5 69279.BG36_03585 2.32e-93 299.0 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,2V8QK@28211|Alphaproteobacteria,43QKU@69277|Phyllobacteriaceae 28211|Alphaproteobacteria L DEAD-like helicases superfamily - - - - - - - - - - - - Helicase_C,ResIII k59_293808_10 794903.OPIT5_29915 3.49e-53 179.0 2E0FE@1|root,32W1M@2|Bacteria,46TEN@74201|Verrucomicrobia 74201|Verrucomicrobia - - - - - - - - - - - - - - DUF932 k59_148668_1 1234888.K0A2R8_9VIRU 4.33e-32 122.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_124894_1 1122135.KB893169_gene2483 9.73e-24 99.0 COG0741@1|root,COG0741@2|Bacteria,1N1XZ@1224|Proteobacteria,2UB2Y@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Transglycosylase SLT domain - - - - - - - - - - - - SLT k59_64085_2 762376.AXYL_04643 1e-26 111.0 COG3756@1|root,COG3756@2|Bacteria,1N7P7@1224|Proteobacteria,2VWCV@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF1376) - - - - - - - - - - - - DUF1376 k59_39157_2 1380356.JNIK01000011_gene1567 9.23e-17 86.3 COG0741@1|root,COG0791@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,2GJX7@201174|Actinobacteria,4EX4A@85013|Frankiales 201174|Actinobacteria M Transglycosylase SLT domain - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60,PG_binding_1,SLT k59_355539_15 259536.Psyc_0471 7.45e-05 45.8 COG4197@1|root,COG4197@2|Bacteria,1QQQK@1224|Proteobacteria,1RTCW@1236|Gammaproteobacteria,3NSJX@468|Moraxellaceae 1236|Gammaproteobacteria S Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT - - - - - - - - - - - - YdaS_antitoxin k59_355539_17 626887.J057_01855 8.41e-44 159.0 COG3756@1|root,COG3756@2|Bacteria,1R95D@1224|Proteobacteria,1RQF3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF1376) - - - - - - - - - - - - DUF1376 k59_355539_18 1120963.KB894501_gene316 2.5e-25 100.0 COG2852@1|root,COG2852@2|Bacteria,1N7EJ@1224|Proteobacteria,1SF5D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - DUF559 k59_173329_1 1304275.C41B8_05453 4.84e-56 208.0 COG0234@1|root,COG0234@2|Bacteria,1NJKP@1224|Proteobacteria 1224|Proteobacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter - - - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - - k59_258244_3 526222.Desal_2352 1.3e-20 93.6 COG5362@1|root,COG5362@2|Bacteria,1PYY9@1224|Proteobacteria,435M3@68525|delta/epsilon subdivisions,2WZZT@28221|Deltaproteobacteria,2M981@213115|Desulfovibrionales 28221|Deltaproteobacteria S TIGRFAM Phage - - - - - - - - - - - - - k59_76004_2 1140.Synpcc7942_0725 7.03e-64 212.0 COG1061@1|root,COG1061@2|Bacteria,1G2HP@1117|Cyanobacteria,1H08U@1129|Synechococcus 1117|Cyanobacteria L Helicase conserved C-terminal domain - - - - - - - - - - - - DUF3427,Helicase_C,ResIII k59_3389_1 1692250.A0A0K1RLR1_9CIRC 1.89e-58 196.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_223243_2 1500894.JQNN01000001_gene3006 0.000707 41.6 COG1476@1|root,COG1476@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_26,HTH_3 k59_65247_2 1423144.Gal_02265 3.28e-30 118.0 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,2TV42@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Terminase large subunit - - - ko:K06909 - - - - ko00000 - - - Terminase_3 k59_259198_2 1121423.JONT01000035_gene915 3.22e-24 99.0 COG3108@1|root,COG3409@1|root,COG3108@2|Bacteria,COG3409@2|Bacteria,1VFRJ@1239|Firmicutes,24R9N@186801|Clostridia,266TJ@186807|Peptococcaceae 186801|Clostridia M Bacterial protein of unknown function (DUF882) - - 3.4.17.14 ko:K08640 - - - - ko00000,ko01000,ko01002,ko01011 - - - PG_binding_1,Peptidase_M15_3 k59_77063_7 279383.Q5DN23_9CAUD 5.08e-16 93.2 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_40337_2 1609634.A0A0C5AFV4_9VIRU 3.75e-131 397.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_174535_1 1219035.NT2_13_00580 3.79e-08 55.8 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_162319_3 1215343.B488_04700 1.93e-13 72.0 2C2XN@1|root,32GT6@2|Bacteria,1REZE@1224|Proteobacteria,2U8HW@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM ERF family protein - - - - - - - - - - - - ERF k59_247121_1 521674.Plim_2104 1.26e-07 55.5 COG0863@1|root,COG0863@2|Bacteria,2IZ0F@203682|Planctomycetes 203682|Planctomycetes L DNA methylase - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_271389_1 1265310.CCBD010000008_gene2859 2.4e-12 64.3 COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,23A39@1762|Mycobacteriaceae 201174|Actinobacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 k59_198739_3 1297742.A176_02388 1.37e-17 85.1 COG0210@1|root,COG0210@2|Bacteria 2|Bacteria L ATP-dependent DNA helicase activity uvrD3 - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_19,PDDEXK_1,UvrD-helicase,UvrD_C k59_185181_2 1121935.AQXX01000096_gene2520 4.21e-14 84.0 COG4733@1|root,COG4733@2|Bacteria,1MXB4@1224|Proteobacteria,1RRUV@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative phage tail protein - - - - - - - - - - - - Phage-tail_3 k59_235136_1 225937.HP15_3095 8.23e-57 197.0 COG4128@1|root,COG4128@2|Bacteria,1N0I7@1224|Proteobacteria,1SAH8@1236|Gammaproteobacteria,46BMP@72275|Alteromonadaceae 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) zot GO:0001906,GO:0006810,GO:0006996,GO:0007010,GO:0008150,GO:0009405,GO:0009987,GO:0016043,GO:0031640,GO:0035821,GO:0042044,GO:0042045,GO:0044364,GO:0044419,GO:0051179,GO:0051234,GO:0051704,GO:0070633,GO:0071840 - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_235136_2 287.DR97_6347 4.17e-11 62.0 2AS3I@1|root,31HG7@2|Bacteria,1QF71@1224|Proteobacteria,1TCAD@1236|Gammaproteobacteria,1YK4E@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_235136_7 1217658.F987_00509 2.5e-51 184.0 2CDPS@1|root,2ZBQT@2|Bacteria,1RB59@1224|Proteobacteria,1S2U0@1236|Gammaproteobacteria,3NKKP@468|Moraxellaceae 1236|Gammaproteobacteria S Phage X family g2p - - - - - - - - - - - Phage_CRI,Phage_X k59_28892_1 1385658.U5KPZ6_9VIRU 1.16e-118 358.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_114578_2 1158607.UAU_01026 5.36e-10 59.7 COG1403@1|root,COG1403@2|Bacteria,1VF1M@1239|Firmicutes,4HNZH@91061|Bacilli,4B6GG@81852|Enterococcaceae 91061|Bacilli V HNH endonuclease - - - ko:K07451 - - - - ko00000,ko01000,ko02048 - - - HNH k59_78463_1 292414.TM1040_1281 8.3e-20 97.4 COG5280@1|root,COG5280@2|Bacteria,1RKKJ@1224|Proteobacteria 1224|Proteobacteria S phage tail tape measure protein - - - - - - - - - - - - PhageMin_Tail k59_54093_2 146922.JOFU01000017_gene3630 1.25e-26 106.0 COG0270@1|root,COG0270@2|Bacteria,2GNB2@201174|Actinobacteria 201174|Actinobacteria L DNA (cytosine-5-)-methyltransferase activity - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - - k59_114582_2 66875.JODY01000031_gene4130 4.4e-26 106.0 COG0237@1|root,COG0237@2|Bacteria,2ISY6@201174|Actinobacteria 201174|Actinobacteria H dephospho-CoA kinase activity - - - - - - - - - - - - - k59_272855_3 543913.D521_1100 3.83e-06 49.3 COG0847@1|root,COG0847@2|Bacteria,1RBBK@1224|Proteobacteria,2VRJK@28216|Betaproteobacteria 28216|Betaproteobacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - - ko:K10857 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - QSregVF_b k59_272855_6 1340829.S5Y5D9_9CAUD 2.23e-30 135.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_248599_5 1234888.K0A2J2_9VIRU 7.4e-128 387.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_103029_8 1609634.A0A0C5AFV4_9VIRU 7.8e-244 686.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_103029_11 1609634.A0A0C5AFT2_9VIRU 1.03e-109 328.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_5897_3 1150626.PHAMO_30121 4.45e-50 193.0 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,2TVGJ@28211|Alphaproteobacteria,2JPR0@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_5897_5 1211115.ALIQ01000188_gene670 1.34e-19 96.7 COG1876@1|root,COG1876@2|Bacteria,1NIJK@1224|Proteobacteria 1224|Proteobacteria M D-alanyl-D-alanine carboxypeptidase - - 3.4.17.14 ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - TMP_2,VanY k59_5897_7 1197951.I6S6K3_9CAUD 2.04e-11 75.5 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_30341_4 1449351.RISW2_21995 1.07e-07 59.7 COG4653@1|root,COG4653@2|Bacteria,1MWU1@1224|Proteobacteria,2TSSY@28211|Alphaproteobacteria 28211|Alphaproteobacteria S phage phi-C31 gp36 major capsid-like protein - - - - - - - - - - - - Phage_capsid k59_200149_2 1609634.A0A0C5AFV4_9VIRU 5.32e-21 95.9 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_186047_1 391626.OAN307_c26420 2.57e-31 134.0 COG3378@1|root,COG3378@2|Bacteria,1MV7I@1224|Proteobacteria,2TRS2@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Phage plasmid primase P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N,Prim-Pol k59_91152_2 927658.AJUM01000034_gene336 6.95e-15 75.1 COG3772@1|root,COG3772@2|Bacteria,4NVJ5@976|Bacteroidetes,2FYU8@200643|Bacteroidia 976|Bacteroidetes G lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_383003_1 1234888.K0A2J2_9VIRU 1.38e-68 229.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_310831_1 105154.Q9MBU6_9VIRU 2.56e-67 222.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_164937_2 371042.NG99_23585 5.32e-73 230.0 28J67@1|root,2Z91Y@2|Bacteria,1R7RG@1224|Proteobacteria,1RZB8@1236|Gammaproteobacteria,3X71A@551|Erwinia 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_164937_3 157783.LK03_13300 1.81e-22 90.5 2D7I9@1|root,32TP3@2|Bacteria,1N2ZM@1224|Proteobacteria,1S9DB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S phage protein ybcO - - - - - - - - - - - DUF1364 k59_237374_3 504472.Slin_1577 2.86e-19 88.6 2DC6Z@1|root,2ZD43@2|Bacteria 2|Bacteria S HNH endonuclease - - - - - - - - - - - - HNH_3 k59_67937_1 743721.Psesu_1175 8.46e-15 80.1 2DNH7@1|root,32XH1@2|Bacteria,1RHPW@1224|Proteobacteria,1T56U@1236|Gammaproteobacteria,1X3WB@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k59_152990_1 570952.ATVH01000011_gene337 6.88e-98 290.0 2CXZV@1|root,32T32@2|Bacteria,1N4R9@1224|Proteobacteria,2UM96@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_288156_1 753084.F4YCL1_9CAUD 4.27e-05 50.8 4QHBW@10239|Viruses,4R0DB@35237|dsDNA viruses no RNA stage,4QSXW@28883|Caudovirales,4QMB4@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_371034_1 1191380.J7HXJ4_9CAUD 6.45e-74 233.0 4QM6S@10699|Siphoviridae 10699|Siphoviridae S PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - - k59_358956_1 1498011.A0A096XUS7_9CAUD 2.14e-59 206.0 4QAUF@10239|Viruses,4QQIV@28883|Caudovirales,4QNZ6@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_8395_1 521098.Aaci_0410 2.54e-44 164.0 COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,4HB81@91061|Bacilli,278S9@186823|Alicyclobacillaceae 91061|Bacilli L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB k59_117374_1 1692244.A0A0K1RLR5_9CIRC 1.69e-81 253.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_227723_1 1283300.ATXB01000002_gene2531 1.78e-45 163.0 COG5511@1|root,COG5511@2|Bacteria,1MVN4@1224|Proteobacteria,1RRK4@1236|Gammaproteobacteria,1XFQ5@135618|Methylococcales 135618|Methylococcales S Phage portal protein, lambda family - - - - - - - - - - - - Phage_portal_2 k59_202886_2 90675.XP_010516935.1 0.000193 49.7 COG0568@1|root,2QVXR@2759|Eukaryota,38A5X@33090|Viridiplantae,3GXSP@35493|Streptophyta,3HRU1@3699|Brassicales 35493|Streptophyta K Sigma factors are initiation factors that promote the attachment of plastid-encoded RNA polymerase (PEP) to specific initiation sites and are then released SIGF GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009416,GO:0009507,GO:0009536,GO:0009628,GO:0009637,GO:0009791,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032501,GO:0032502,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071214,GO:0071478,GO:0071482,GO:0071483,GO:0071704,GO:0080090,GO:0090304,GO:0090351,GO:0097659,GO:0104004,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2000142,GO:2001141 - - - - - - - - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k59_33173_3 205870.Q857J9_BPMB2 1.02e-59 195.0 4QBDE@10239|Viruses,4QZ15@35237|dsDNA viruses no RNA stage,4QTX9@28883|Caudovirales,4QKXK@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_8556_2 113395.AXAI01000008_gene980 7.21e-20 92.0 COG0073@1|root,COG0073@2|Bacteria,1NKFN@1224|Proteobacteria 1224|Proteobacteria J RNA ligase - - - - - - - - - - - - RNA_ligase k59_239177_1 1141137.K4FBB3_9CAUD 4.81e-19 98.2 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_239177_3 488538.SAR116_0386 1.75e-58 191.0 COG1351@1|root,COG1351@2|Bacteria,1MWY8@1224|Proteobacteria,2TTER@28211|Alphaproteobacteria,4BRKK@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant thyX - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 k59_239177_7 1197951.I6R0Z0_9CAUD 5.56e-43 155.0 4QGZN@10239|Viruses,4R0FF@35237|dsDNA viruses no RNA stage,4QTUK@28883|Caudovirales 28883|Caudovirales S nuclease activity - - - - - - - - - - - - - k59_216104_2 1038860.AXAP01000010_gene7671 2.25e-06 57.8 COG1749@1|root,COG1749@2|Bacteria,1QWWE@1224|Proteobacteria,2TX6F@28211|Alphaproteobacteria,3JXIB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria N Domain of unknown function (DUF4082) - - - - - - - - - - - - DUF4082,He_PIG k59_142364_1 176275.XP_008593753.1 5.77e-08 54.7 COG1061@1|root,2QT4U@2759|Eukaryota,38GE0@33154|Opisthokonta,3NWXY@4751|Fungi,3QQHS@4890|Ascomycota,2144C@147550|Sordariomycetes,3TETK@5125|Hypocreales 4751|Fungi A DEAD DEAH box helicase irc3 GO:0000002,GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005739,GO:0005759,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0007005,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010467,GO:0010501,GO:0016043,GO:0016070,GO:0016072,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022613,GO:0031974,GO:0031981,GO:0032042,GO:0033676,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042623,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070035,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 - ko:K17677 - - - - ko00000,ko01000,ko03029 - - - Helicase_C,ResIII k59_142364_3 1203554.HMPREF1476_00223 3.2e-32 128.0 COG5377@1|root,COG5377@2|Bacteria,1MWP8@1224|Proteobacteria,2VJH5@28216|Betaproteobacteria,4PR24@995019|Sutterellaceae 28216|Betaproteobacteria L YqaJ-like viral recombinase domain - - - - - - - - - - - - YqaJ k59_130552_1 1537917.JU82_03700 6.1e-70 223.0 COG0553@1|root,COG0553@2|Bacteria 2|Bacteria L helicase activity - - - - - - - - - - - - Helicase_C,PLDc_2,ResIII,SNF2_N k59_107079_1 1788442.A0A190WH98_9CIRC 1.84e-07 53.9 4QB6C@10239|Viruses,4QUKM@29258|ssDNA viruses 10239|Viruses J Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_204411_1 1122247.C731_3017 1.26e-266 749.0 2ANQ2@1|root,31DPJ@2|Bacteria,2I9V0@201174|Actinobacteria,23B0K@1762|Mycobacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_204411_2 1327776.R4JHA8_9CAUD 1.66e-47 157.0 4QBGR@10239|Viruses,4QWM3@35237|dsDNA viruses no RNA stage,4QPDT@28883|Caudovirales,4QMK4@10699|Siphoviridae 10699|Siphoviridae S Protein of unknown function (DUF2744) - - - - - - - - - - - - - k59_350308_3 1041147.AUFB01000009_gene1869 2.31e-20 87.8 2EU9D@1|root,33MRT@2|Bacteria,1NCDT@1224|Proteobacteria,2V57U@28211|Alphaproteobacteria,4BKT8@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_350308_4 1095772.CAHH01000063_gene639 1.67e-38 140.0 2EES9@1|root,338JX@2|Bacteria,2H5MY@201174|Actinobacteria 201174|Actinobacteria L RNase_H superfamily - - - - - - - - - - - - RNase_H_2 k59_96091_1 1219076.N646_1398 4.49e-18 80.9 2EVSB@1|root,33P68@2|Bacteria,1P3SK@1224|Proteobacteria,1SS80@1236|Gammaproteobacteria,1XYJ3@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1353) - - - - - - - - - - - - DUF1353 k59_217566_1 1609634.A0A0C5AFV4_9VIRU 4.45e-64 214.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_302421_2 1122244.AUGF01000025_gene1891 3.77e-15 70.1 290I0@1|root,2ZN6X@2|Bacteria,1P4Z9@1224|Proteobacteria,1SV8W@1236|Gammaproteobacteria,3NSC2@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_264590_1 1609634.A0A0C5AFV4_9VIRU 8.99e-72 234.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_264590_3 1165094.RINTHH_3920 1.86e-69 225.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_264590_6 105154.Q9MBU3_9VIRU 1.5e-17 84.0 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_264590_7 186617.M9M8L2_9VIRU 4.81e-49 177.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_374123_2 49964.Q94MS1_9CAUD 3.45e-43 150.0 4QB4H@10239|Viruses,4QYQI@35237|dsDNA viruses no RNA stage,4QUAR@28883|Caudovirales,4QNUV@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_131987_2 1618247.A0A0C5IMK7_9CIRC 5.09e-08 60.1 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_361609_1 758.BBIX01000009_gene1627 1.57e-30 119.0 2B9XI@1|root,323AV@2|Bacteria,1NZM3@1224|Proteobacteria,1SQ2M@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Protein of unknown function (DUF1071) - - - - - - - - - - - - DUF1071 k59_265857_1 1574422.A0A0A1ENW9_9CIRC 1.59e-21 99.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_36116_1 1986029.Q9MBM3_9VIRU 3.13e-23 99.8 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_205729_1 426117.M446_4151 1.8e-22 93.6 COG0137@1|root,COG0137@2|Bacteria,1MYHX@1224|Proteobacteria,2UJMK@28211|Alphaproteobacteria,1JW7B@119045|Methylobacteriaceae 28211|Alphaproteobacteria E Protein of unknown function (DUF2493) - - - - - - - - - - - - DUF2493 k59_47832_1 669262.COK_0677 1.41e-06 57.8 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,1S0WX@1236|Gammaproteobacteria,1Y93K@135625|Pasteurellales 135625|Pasteurellales S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6C k59_10920_2 160492.XF_2086 8.61e-32 119.0 2DR48@1|root,33A3G@2|Bacteria,1NN7E@1224|Proteobacteria,1TD8K@1236|Gammaproteobacteria,1XABM@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k59_181905_1 1517416.IDAT_10860 3.43e-17 90.9 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,2QFWD@267893|Idiomarinaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_22151_1 1476390.A0A060RJ50_9CAUD 9.26e-63 218.0 4QBSJ@10239|Viruses,4QXH4@35237|dsDNA viruses no RNA stage,4QPFJ@28883|Caudovirales,4QKUK@10699|Siphoviridae 10699|Siphoviridae S DNA primase activity - - - - - - - - - - - - - k59_230804_1 1504822.CCNO01000015_gene594 1.47e-37 143.0 COG0553@1|root,COG0863@1|root,COG0553@2|Bacteria,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_339909_1 1211640.K4K5Z9_9CAUD 1.55e-16 77.4 4QF35@10239|Viruses,4QPS1@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_157652_1 1214242.B446_23425 3.22e-05 48.9 COG3469@1|root,COG3469@2|Bacteria,2GJH0@201174|Actinobacteria 201174|Actinobacteria G Belongs to the glycosyl hydrolase 18 family chiA - - - - - - - - - - - CBM_4_9,Glyco_hydro_18,fn3 k59_60069_1 1327977.S0A0N2_9CAUD 2.93e-93 298.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales 28883|Caudovirales S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_60069_2 213777.R9R1N7_9CAUD 2.03e-12 65.1 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QKM7@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k59_351703_2 563123.B5U5I0_9CAUD 2.01e-26 106.0 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QKM7@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k59_108523_2 691965.D4P7D6_9CAUD 5.46e-70 236.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_241936_3 1165094.RINTHH_3920 7.61e-58 191.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_84805_1 177439.DP1517 3.55e-49 163.0 COG0847@1|root,COG0847@2|Bacteria 2|Bacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k59_340052_1 1157634.KB912959_gene1714 3.54e-43 150.0 2C5J1@1|root,3067M@2|Bacteria,2IKFX@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_11085_1 279280.Q6J1R5_9CAUD 6.06e-09 64.3 4QC24@10239|Viruses,4QZPR@35237|dsDNA viruses no RNA stage,4QRZK@28883|Caudovirales,4QP0N@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_328599_3 1609634.A0A0C5AFV4_9VIRU 3.61e-219 624.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_36940_1 91464.S7335_1407 1.19e-52 189.0 COG0507@1|root,COG0507@2|Bacteria,1G8N5@1117|Cyanobacteria,1GZPG@1129|Synechococcus 1117|Cyanobacteria L COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member - - 3.1.11.5 ko:K01144 - - - - ko00000,ko01000 - - - AAA_30,UvrD_C_2 k59_36940_3 574087.Acear_0340 9.72e-30 136.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,3WAIG@53433|Halanaerobiales 186801|Clostridia L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_24786_1 2003327.CAPSD_BPCHP 9.33e-63 215.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_109865_1 386456.JQKN01000009_gene1161 5.89e-07 52.8 COG1520@1|root,COG3291@1|root,arCOG02516@1|root,arCOG02552@1|root,arCOG02492@2157|Archaea,arCOG02508@2157|Archaea,arCOG02516@2157|Archaea,arCOG02552@2157|Archaea,2Y7Q0@28890|Euryarchaeota 28890|Euryarchaeota KLT COG1520 FOG WD40-like repeat - - - - - - - - - - - - CHB_HEX_C_1,PKD,PQQ_3 k59_49229_3 1122201.AUAZ01000017_gene2950 4.34e-13 70.1 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,1RY1X@1236|Gammaproteobacteria,46BED@72275|Alteromonadaceae 1236|Gammaproteobacteria S associated with various cellular activities - - - - - - - - - - - - AAA,AAA_5 k59_328642_1 1234888.K0A2J2_9VIRU 1.03e-69 233.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_12570_1 691965.D4P7I0_9CAUD 4.16e-29 112.0 4QDSZ@10239|Viruses,4QXJ8@35237|dsDNA viruses no RNA stage,4QPKE@28883|Caudovirales,4QM8R@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_158569_2 907931.AEIZ01000007_gene672 1.68e-13 70.1 COG3774@1|root,COG3774@2|Bacteria,1V3YG@1239|Firmicutes,4HXBN@91061|Bacilli,4AYJW@81850|Leuconostocaceae 91061|Bacilli M Glycosyltransferase sugar-binding region containing DXD motif - - - - - - - - - - - - Gly_transf_sug k59_340610_2 1122132.AQYH01000015_gene2272 1.54e-66 217.0 2C5GI@1|root,2Z8C1@2|Bacteria,1R8XM@1224|Proteobacteria,2TUME@28211|Alphaproteobacteria,4BJKS@82115|Rhizobiaceae 28211|Alphaproteobacteria S P22 coat protein - gene protein 5 - - - - - - - - - - - - P22_CoatProtein k59_328643_1 323848.Nmul_A2202 1.62e-35 142.0 COG0438@1|root,COG0438@2|Bacteria,1PJ7G@1224|Proteobacteria,2W2A5@28216|Betaproteobacteria,373ZR@32003|Nitrosomonadales 28216|Betaproteobacteria M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_transf_4 k59_122044_3 1609634.A0A0C5AFT2_9VIRU 6.93e-129 378.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_122044_6 1609634.A0A0C5AFV4_9VIRU 1.2e-95 297.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_365245_10 1556290.A0A0A0RM00_9CAUD 6.12e-49 174.0 4QAXQ@10239|Viruses,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_182934_2 6334.EFV55995 6.67e-13 70.9 COG0008@1|root,KOG1149@2759|Eukaryota,38CS1@33154|Opisthokonta,3B9AD@33208|Metazoa,3D01P@33213|Bilateria,40BRC@6231|Nematoda 33208|Metazoa J Belongs to the class-I aminoacyl-tRNA synthetase family EARS2 GO:0000959,GO:0003674,GO:0003824,GO:0004812,GO:0004818,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006424,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032543,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050561,GO:0070127,GO:0071704,GO:0090304,GO:0140053,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c k59_110360_1 1307759.JOMJ01000004_gene2473 4.11e-06 51.6 29XPE@1|root,30JF0@2|Bacteria,1Q0TH@1224|Proteobacteria,435Z8@68525|delta/epsilon subdivisions,2WXMG@28221|Deltaproteobacteria,2MC96@213115|Desulfovibrionales 28221|Deltaproteobacteria S Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_2 k59_365284_2 160488.PP_2273 1.13e-47 173.0 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,1SJP1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA polymerase family A - - - - - - - - - - - - DNA_pol_A k59_110363_1 426355.Mrad2831_5687 3.46e-12 68.2 2E4HT@1|root,32ZCW@2|Bacteria,1NC3H@1224|Proteobacteria,2UHMD@28211|Alphaproteobacteria,1JWRK@119045|Methylobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_207694_1 1226994.AMZB01000079_gene96 2.09e-07 62.8 2CZBU@1|root,32T60@2|Bacteria,1N7TC@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_61935_1 1122971.BAME01000146_gene6515 7.07e-15 79.7 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,4P0VD@976|Bacteroidetes,2FMKK@200643|Bacteroidia 976|Bacteroidetes L Psort location Cytoplasmic, score 8.96 - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - AAA_25,DnaB_C,Toprim_2,Toprim_4 k59_243853_1 329254.Q2NPG0_9CAUD 1.61e-30 116.0 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QKM7@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k59_73959_1 1234888.K0A2J2_9VIRU 7.82e-15 73.9 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_73959_6 1234888.K0A2J2_9VIRU 2.83e-79 253.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_304819_2 1126411.I1TEL3_9CIRC 3.91e-19 89.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_134473_2 1460634.JCM19037_4158 8.07e-08 51.2 2EI5I@1|root,33BWX@2|Bacteria,1W0I2@1239|Firmicutes,4HYE0@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k59_341104_1 105154.Q9MBU6_9VIRU 0.000925 41.6 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_85970_2 1692253.A0A0K1RLM4_9CIRC 3.27e-33 134.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_316929_1 1385658.U5KNR1_9VIRU 6.13e-17 81.3 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_316929_2 145579.C_BPPHM 2.94e-06 48.1 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_316929_3 1385658.U5KPZ6_9VIRU 1.66e-206 591.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_316929_4 105154.Q9MBU3_9VIRU 1.77e-18 86.7 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_316929_7 1385658.U5KNR1_9VIRU 1.29e-53 181.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_353539_1 1500301.JQMF01000006_gene1767 1.2e-53 179.0 2AFZH@1|root,3163D@2|Bacteria,1RJUP@1224|Proteobacteria,2UI0N@28211|Alphaproteobacteria,4BK5T@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_37389_1 1379719.S5TMX6_9CIRC 6.3e-21 91.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_49701_1 1234888.K0A2J2_9VIRU 2.07e-67 224.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_135088_2 1618260.A0A0C5I2C5_9CIRC 1.33e-55 187.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_159660_1 97139.C824_05152 1.13e-09 63.9 COG0535@1|root,COG0535@2|Bacteria,1V348@1239|Firmicutes,24GVU@186801|Clostridia 186801|Clostridia C Radical SAM superfamily - - - - - - - - - - - - Fer4_12,Radical_SAM,SPASM k59_341650_2 1123276.KB893246_gene579 1.5e-07 57.0 COG3306@1|root,COG3306@2|Bacteria,4PMXM@976|Bacteroidetes,47Y9M@768503|Cytophagia 976|Bacteroidetes M glycosyltransferase involved in LPS biosynthesis - - - - - - - - - - - - - k59_74582_4 1201293.AKXQ01000048_gene1286 3.17e-25 100.0 2E645@1|root,330T3@2|Bacteria,1NEGX@1224|Proteobacteria,1SC3K@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_74582_6 1121373.KB903639_gene3773 1.04e-14 73.2 2DMPB@1|root,32SV8@2|Bacteria,4NSG4@976|Bacteroidetes,47SFC@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_74582_8 498211.CJA_0728 6.37e-51 169.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,1FH39@10|Cellvibrio 1236|Gammaproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_74582_14 411468.CLOSCI_00315 1.6e-39 141.0 COG4712@1|root,COG4712@2|Bacteria,1V7HG@1239|Firmicutes,24GFS@186801|Clostridia 186801|Clostridia S double-strand break repair protein - - - - - - - - - - - - Rad52_Rad22 k59_74582_15 637910.ROD_03751 1.46e-25 104.0 COG1403@1|root,COG1403@2|Bacteria,1NE62@1224|Proteobacteria,1S9QW@1236|Gammaproteobacteria 1236|Gammaproteobacteria V HNH nucleases - - - - - - - - - - - - HNH k59_183321_1 1609634.A0A0C5AFT2_9VIRU 1.42e-22 99.8 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_220573_1 626887.J057_01785 8.24e-58 200.0 2DCM2@1|root,32TZV@2|Bacteria,1NAGE@1224|Proteobacteria,1SMRS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_220573_2 428125.CLOLEP_01405 3.75e-45 150.0 2AIHK@1|root,318ZG@2|Bacteria,1V7P0@1239|Firmicutes,24KNU@186801|Clostridia,3WNH7@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_196074_1 1380355.JNIJ01000092_gene3853 2.23e-18 89.0 COG0358@1|root,COG3598@1|root,COG0358@2|Bacteria,COG3598@2|Bacteria,1R4GJ@1224|Proteobacteria,2TUNT@28211|Alphaproteobacteria,3K3VQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L AAA domain - - - - - - - - - - - - AAA_25 k59_293467_3 105154.Q9MBU6_9VIRU 2.89e-78 249.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_220643_1 665950.HMPREF1025_02545 3.78e-36 134.0 COG0863@1|root,COG0863@2|Bacteria,1VRVB@1239|Firmicutes,24GNY@186801|Clostridia,27PFY@186928|unclassified Lachnospiraceae 186801|Clostridia L DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_220643_2 1313421.JHBV01000006_gene322 5.09e-24 97.4 COG0338@1|root,COG0338@2|Bacteria 2|Bacteria L D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_232492_7 926550.CLDAP_14930 5.68e-26 102.0 COG0629@1|root,COG0629@2|Bacteria,2G6YE@200795|Chloroflexi 200795|Chloroflexi L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_378796_2 445970.ALIPUT_01194 2.19e-10 61.6 2E8S0@1|root,3332X@2|Bacteria,4NWIA@976|Bacteroidetes,2FUQI@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_378796_3 517417.Cpar_1293 8.85e-52 176.0 COG0302@1|root,COG0302@2|Bacteria,1FD81@1090|Chlorobi 1090|Chlorobi F PFAM GTP cyclohydrolase I folE - 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI k59_378796_4 1313421.JHBV01000036_gene2445 1.76e-63 205.0 COG0602@1|root,COG0602@2|Bacteria 2|Bacteria H queuosine metabolic process queE GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047 1.97.1.4,4.3.99.3 ko:K04068,ko:K10026 ko00790,ko01100,map00790,map01100 - R04710,R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_12,Fer4_14,Radical_SAM k59_378796_5 1229276.DI53_1323 7.06e-31 113.0 COG0720@1|root,COG0720@2|Bacteria,4NM8H@976|Bacteroidetes 976|Bacteroidetes H 6-pyruvoyl tetrahydropterin synthase queD - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS k59_330489_1 1636271.A0A0E3M3Z1_9CAUD 1.24e-52 181.0 4QAIK@10239|Viruses,4QPEB@28883|Caudovirales,4QKNC@10699|Siphoviridae 10699|Siphoviridae S hydrolase activity - - - - - - - - - - - - - k59_293845_1 869209.Tresu_0626 3.18e-05 51.6 COG0740@1|root,COG0740@2|Bacteria,2J78H@203691|Spirochaetes 203691|Spirochaetes OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP-2 - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease k59_172301_3 691965.D4P7C5_9CAUD 1.32e-66 218.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_99428_1 272568.GDI3670 2.14e-28 121.0 COG0234@1|root,COG0234@2|Bacteria,1NJKP@1224|Proteobacteria,2UM25@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter - - - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - - k59_50904_1 1406780.U5PWM1_9CAUD 4.64e-11 64.7 4QDXM@10239|Viruses,4QWIX@35237|dsDNA viruses no RNA stage,4QQF6@28883|Caudovirales,4QNXH@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_75122_4 1234888.K0A2J2_9VIRU 4.34e-161 472.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_257385_2 1052684.PPM_3312 2.52e-28 116.0 COG3723@1|root,COG3723@2|Bacteria,1UNDF@1239|Firmicutes,4HB2T@91061|Bacilli,26XPY@186822|Paenibacillaceae 91061|Bacilli L repair protein recT - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_63306_1 102129.Lepto7375DRAFT_7273 1.22e-16 77.4 2EHVE@1|root,33BKZ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_183776_1 948071.S4S2D9_9CAUD 1.64e-170 499.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae 10744|Podoviridae S ribonucleoside-triphosphate reductase activity - - - - - - - - - - - - - k59_50917_2 1493507.A0A0E3F2L4_9CAUD 5.85e-32 117.0 4QBC7@10239|Viruses,4QUQW@35237|dsDNA viruses no RNA stage,4QPGT@28883|Caudovirales,4QIH8@10662|Myoviridae 10662|Myoviridae S Pfam:Phage_clamp_A - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039686,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_318509_1 428125.CLOLEP_01421 6.99e-40 136.0 2ARVA@1|root,31H70@2|Bacteria,1V7JT@1239|Firmicutes,24JPE@186801|Clostridia,3WP7W@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - HK97-gp10_like k59_342424_1 1528106.JRJE01000004_gene471 7.88e-11 61.2 COG0741@1|root,COG0741@2|Bacteria,1N0U8@1224|Proteobacteria,2UICK@28211|Alphaproteobacteria,2JTZJ@204441|Rhodospirillales 204441|Rhodospirillales M lytic transglycosylase activity - - - - - - - - - - - - - k59_148474_1 1126411.I1TEL3_9CIRC 9.25e-43 155.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_87978_1 472175.EL18_02063 1.74e-102 305.0 COG3926@1|root,COG3926@2|Bacteria,1MVXW@1224|Proteobacteria,2TT3H@28211|Alphaproteobacteria,43JWV@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S secretion activating protein - - - - - - - - - - - - Glyco_hydro_108,PG_binding_3 k59_63904_2 1509405.GV67_04245 2.5e-24 97.8 COG3023@1|root,COG3023@2|Bacteria,1N032@1224|Proteobacteria,2U6P9@28211|Alphaproteobacteria,4BHDN@82115|Rhizobiaceae 28211|Alphaproteobacteria V N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2,PG_binding_1 k59_233766_3 1151126.AQYI01000003_gene546 1.27e-25 99.0 2CENH@1|root,2ZRPR@2|Bacteria,2IPB4@201174|Actinobacteria 201174|Actinobacteria - - - - 3.1.1.29 ko:K04794 - - - - ko00000,ko01000,ko03012 - - - - k59_319146_2 1692256.A0A0K1RL85_9CIRC 3.68e-117 345.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_379498_2 1986029.Q9MBM6_9VIRU 7.42e-24 98.2 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_319150_3 202956.BBNL01000011_gene2397 1.79e-11 67.4 COG0338@1|root,COG0338@2|Bacteria,1NTIK@1224|Proteobacteria,1RSG6@1236|Gammaproteobacteria,3NMP8@468|Moraxellaceae 1236|Gammaproteobacteria L D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_283296_1 753084.F4YCI4_9CAUD 7.91e-47 168.0 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QS4V@28883|Caudovirales,4QKNC@10699|Siphoviridae 10699|Siphoviridae S hydrolase activity - - - - - - - - - - - - - k59_197332_1 428125.CLOLEP_01422 2.26e-135 434.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,3WN92@541000|Ruminococcaceae 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_197332_2 691965.D4P7E5_9CAUD 3.41e-45 150.0 4QEVD@10239|Viruses,4QW84@35237|dsDNA viruses no RNA stage,4QQSX@28883|Caudovirales,4QMU4@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_51522_4 1609634.A0A0C5AFT2_9VIRU 7.47e-47 159.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_294589_4 1234888.K0A2J2_9VIRU 1.89e-109 337.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_355406_1 153496.JNAB01000037_gene451 3.05e-07 57.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TRIQ@28211|Alphaproteobacteria,2JQ62@204441|Rhodospirillales 204441|Rhodospirillales E Belongs to the DegT DnrJ EryC1 family - - - - - - - - - - - - DegT_DnrJ_EryC1 k59_222071_2 2074.JNYD01000012_gene309 4.93e-18 89.0 COG1674@1|root,COG1674@2|Bacteria 2|Bacteria D ftsk spoiiie traA - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE k59_295054_5 717785.HYPMC_1228 9.11e-09 57.8 2E6JI@1|root,3316K@2|Bacteria,1PP48@1224|Proteobacteria,2UT9Y@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_51981_1 411460.RUMTOR_01335 1.02e-89 324.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_173586_1 1217708.F887_01930 1.77e-30 116.0 29E11@1|root,300Z0@2|Bacteria,1RD0D@1224|Proteobacteria,1S05E@1236|Gammaproteobacteria,3NNB9@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_270487_11 1266909.AUAG01000012_gene979 5.16e-08 58.5 COG0210@1|root,COG0210@2|Bacteria,1R4PV@1224|Proteobacteria,1RZXT@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA helicase - - - - - - - - - - - - AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2 k59_64441_3 1175654.A0A0S0N897_9CAUD 8.84e-40 147.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_283927_1 1055815.AYYA01000072_gene2273 6.12e-16 80.9 COG0001@1|root,COG1861@1|root,COG0001@2|Bacteria,COG1861@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,3NJSW@468|Moraxellaceae 1236|Gammaproteobacteria H Glutamate-1-semialdehyde aminotransferase - - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3,CTP_transf_3 k59_149184_3 158787.BSCA_0758 8.17e-06 48.9 COG4570@1|root,COG4570@2|Bacteria,2GQT6@201174|Actinobacteria,4D1DZ@85004|Bifidobacteriales 201174|Actinobacteria L Endodeoxyribonuclease RusA - - - - - - - - - - - - RusA k59_161578_2 644076.SCH4B_3121 3.45e-11 63.9 2C0AZ@1|root,33W05@2|Bacteria,1NVUT@1224|Proteobacteria,2USJ8@28211|Alphaproteobacteria,4NDNA@97050|Ruegeria 28211|Alphaproteobacteria S Protein of unknown function (DUF3168) - - - - - - - - - - - - DUF3168 k59_3711_2 1385658.U5KPZ6_9VIRU 3.16e-87 279.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_367640_2 756067.MicvaDRAFT_0879 8.21e-07 53.5 COG0241@1|root,COG0241@2|Bacteria,1G8EU@1117|Cyanobacteria,1HD16@1150|Oscillatoriales 1117|Cyanobacteria E Polynucleotide kinase 3 phosphatase - - 3.1.3.82,3.1.3.83 ko:K03273 ko00540,ko01100,map00540,map01100 M00064 R05647,R09771 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - - HAD_2,PNK3P k59_197869_4 1121441.AUCX01000022_gene766 3.57e-74 249.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,42QC5@68525|delta/epsilon subdivisions,2WVD2@28221|Deltaproteobacteria,2MCDS@213115|Desulfovibrionales 28221|Deltaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_149186_2 1443113.LC20_04195 1.94e-29 109.0 COG3179@1|root,COG3179@2|Bacteria,1RE8K@1224|Proteobacteria,1S4U8@1236|Gammaproteobacteria 1236|Gammaproteobacteria S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Peptidase_M15_4 k59_112731_1 1211115.ALIQ01000188_gene655 1.44e-46 169.0 28MS5@1|root,2ZB0J@2|Bacteria,1PTV9@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_368324_1 1210884.HG799463_gene9734 3.95e-17 90.9 COG3378@1|root,COG3378@2|Bacteria 2|Bacteria KL Phage plasmid primase P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,zf-CHC2 k59_356469_1 1986029.Q9MBM3_9VIRU 4.74e-52 179.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_113318_1 438753.AZC_3597 6.94e-63 212.0 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,2TVEI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA polymerase family A - - - - - - - - - - - - DNA_pol_A k59_76974_7 768710.DesyoDRAFT_3132 2.05e-23 115.0 COG5280@1|root,COG5280@2|Bacteria,1UJ98@1239|Firmicutes,24BN7@186801|Clostridia,264YJ@186807|Peptococcaceae 186801|Clostridia S Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_101500_1 411460.RUMTOR_01339 4.14e-09 57.4 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_15366_1 1692249.A0A0K1RL40_9CIRC 1.57e-50 175.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_65175_2 1410634.JHVD01000028_gene2088 5.34e-05 49.7 COG2369@1|root,COG2369@2|Bacteria,2I9N4@201174|Actinobacteria,4DRHY@85009|Propionibacteriales 201174|Actinobacteria S Phage Mu protein F like protein - - - - - - - - - - - - Phage_Mu_F k59_40220_1 1234888.K0A2J2_9VIRU 8.5e-78 253.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_211153_1 1609634.A0A0C5ANA6_9VIRU 4.68e-24 102.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_211153_2 1609634.A0A0C5AFV4_9VIRU 4.94e-29 115.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_234901_1 156889.Mmc1_1716 1.16e-141 410.0 28NGF@1|root,2ZBII@2|Bacteria,1R9KY@1224|Proteobacteria,2U1P7@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_4370_1 1618254.A0A0C5IBG4_9CIRC 4.55e-131 380.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_175094_1 926564.KI911577_gene454 9.13e-89 285.0 COG0358@1|root,COG3378@1|root,COG0358@2|Bacteria,COG3378@2|Bacteria,2H1DT@201174|Actinobacteria 201174|Actinobacteria T Phage plasmid primase, P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,Toprim_2 k59_235468_1 1009370.ALO_12376 5.84e-08 55.1 2EC8I@1|root,33670@2|Bacteria,1VENI@1239|Firmicutes,4H668@909932|Negativicutes 909932|Negativicutes - - - - - - - - - - - - - - - k59_65745_1 395494.Galf_2029 8.55e-14 72.4 COG1917@1|root,COG1917@2|Bacteria,1P4U6@1224|Proteobacteria 1224|Proteobacteria S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - - k59_333011_2 1692255.A0A0K1RL52_9CIRC 4.73e-30 118.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_285623_1 1410666.JHXG01000008_gene681 2.37e-05 45.1 COG4734@1|root,COG4734@2|Bacteria 2|Bacteria S Antirestriction protein (ArdA) ardA - - - - - - - - - - - ArdA k59_150543_2 1121935.AQXX01000137_gene3944 1.03e-15 82.8 28W3B@1|root,2ZI47@2|Bacteria,1P68T@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_259657_3 1238237.CP10139811_0883 4.01e-16 90.9 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2JFW6@204428|Chlamydiae 204428|Chlamydiae L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_368952_2 1382303.JPOM01000001_gene2089 6.77e-28 107.0 COG3772@1|root,COG3772@2|Bacteria,1N0ZQ@1224|Proteobacteria,2UFT6@28211|Alphaproteobacteria 28211|Alphaproteobacteria S lysozyme - - - - - - - - - - - - Phage_lysozyme k59_29366_3 105154.Q9MBU6_9VIRU 1.52e-38 142.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_285625_1 575589.HMPREF0018_00186 1.65e-52 184.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,1S4YH@1236|Gammaproteobacteria,3NT8Q@468|Moraxellaceae 1236|Gammaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_150547_1 2003327.CAPSD_BPCHP 8.41e-34 132.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_344942_1 663278.Ethha_0496 3.98e-19 87.0 COG4653@1|root,COG4653@2|Bacteria,1UZMZ@1239|Firmicutes,24BQJ@186801|Clostridia,3WR58@541000|Ruminococcaceae 186801|Clostridia S Phage capsid family - - - - - - - - - - - - CarboxypepD_reg,Phage_capsid k59_344942_7 1149133.ppKF707_0745 3.22e-131 389.0 COG0863@1|root,COG0863@2|Bacteria,1QXR3@1224|Proteobacteria,1T3H2@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K07319 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_126537_1 160488.PP_2266 6.13e-48 174.0 COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria,1SM2Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria K DNA-dependent RNA polymerase - - 2.7.7.6 ko:K21313 - - - - ko00000,ko01000,ko03200 - - - RNA_pol,RPOL_N k59_381419_2 471874.PROSTU_01885 6.81e-26 112.0 COG4643@1|root,COG4643@2|Bacteria,1MW9E@1224|Proteobacteria,1RXXG@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zinc-binding domain of primase-helicase - - - - - - - - - - - - Prim_Zn_Ribbon,Toprim_3 k59_381419_5 411470.RUMGNA_02049 9.19e-25 98.6 2C6KN@1|root,32Y69@2|Bacteria,1VANX@1239|Firmicutes,24MNG@186801|Clostridia,3Y12A@572511|Blautia 186801|Clostridia S VRR-NUC domain - - - - - - - - - - - - VRR_NUC k59_271911_2 1609634.A0A0C5ANA6_9VIRU 2.74e-16 82.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_271911_4 1609634.A0A0C5AFV4_9VIRU 6.44e-23 97.1 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_211926_1 1211115.ALIQ01000188_gene633 1.14e-16 84.0 COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,2TU4W@28211|Alphaproteobacteria,3ND09@45404|Beijerinckiaceae 28211|Alphaproteobacteria L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_162870_2 1219035.NT2_13_00580 2.54e-44 167.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_41705_1 1211777.BN77_4169 7.93e-87 270.0 2C5GI@1|root,2Z8C1@2|Bacteria,1R8XM@1224|Proteobacteria,2TUME@28211|Alphaproteobacteria,4BJKS@82115|Rhizobiaceae 28211|Alphaproteobacteria S P22 coat protein - gene protein 5 - - - - - - - - - - - - P22_CoatProtein k59_102817_1 410359.Pcal_1351 1.73e-05 50.1 arCOG05626@1|root,arCOG05626@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - k59_66452_3 186617.M9M8L2_9VIRU 2.39e-48 180.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_272855_14 278957.ABEA03000182_gene1978 2.06e-37 143.0 COG2730@1|root,COG2730@2|Bacteria,46XJ7@74201|Verrucomicrobia,3K99G@414999|Opitutae 414999|Opitutae G Belongs to the glycosyl hydrolase 5 (cellulase A) family - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - Cellulase k59_272855_16 1315956.M9QRJ5_9CAUD 9.98e-12 68.9 4QD6Y@10239|Viruses,4QWG5@35237|dsDNA viruses no RNA stage,4QPFN@28883|Caudovirales,4QKM9@10699|Siphoviridae 10699|Siphoviridae S DNA N-6-adenine-methyltransferase (Dam) - - - - - - - - - - - - - k59_272855_18 5932.XP_004037347.1 2.44e-21 102.0 COG1793@1|root,2QTYC@2759|Eukaryota,3ZBNY@5878|Ciliophora 5878|Ciliophora L DNA ligase OB-like domain - - 6.5.1.1,6.5.1.6,6.5.1.7 ko:K10747 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00381,R00382,R10822,R10823 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_ligase_A_M,DNA_ligase_OB_2 k59_272855_19 247490.KSU1_C1486 3.64e-21 88.6 COG1694@1|root,COG1694@2|Bacteria 2|Bacteria FG Mazg nucleotide pyrophosphohydrolase - - - - - - - - - - - - MazG,MazG-like k59_272855_23 673376.F2VHW0_9CAUD 2.41e-24 97.8 4QAZF@10239|Viruses,4QUTY@35237|dsDNA viruses no RNA stage,4QPH6@28883|Caudovirales,4QM17@10699|Siphoviridae 10699|Siphoviridae S Protein of unknwon function (DUF3310) - - - - - - - - - - - - - k59_163646_1 2003327.CAPSD_BPCHP 2.35e-20 102.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_248435_2 67267.JNXT01000054_gene2989 1.04e-12 73.6 2F1HE@1|root,33UHX@2|Bacteria,2IH41@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_185920_1 272623.L49824 1.69e-05 48.5 COG4712@1|root,COG4712@2|Bacteria,1VENV@1239|Firmicutes,4HX6K@91061|Bacilli 91061|Bacilli S Rad52/22 family double-strand break repair protein - - - - - - - - - - - - Rad52_Rad22 k59_102870_2 349161.Dred_0887 2.14e-05 49.3 COG1476@1|root,COG1476@2|Bacteria 2|Bacteria K sequence-specific DNA binding XK27_07105 - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_26,HTH_3 k59_236175_4 1443910.W0GAI5_9VIRU 8.74e-11 68.9 4QE84@10239|Viruses,4QUKR@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_297383_1 2003327.CAPSD_BPCHP 5.57e-27 114.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_175944_1 691965.D4P7C5_9CAUD 1.72e-25 104.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_175944_2 411460.RUMTOR_01350 3.83e-09 59.7 2EAAT@1|root,334F2@2|Bacteria,1VJJI@1239|Firmicutes,24TQU@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_272865_1 1385658.U5KPZ6_9VIRU 1.34e-39 146.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_42609_2 1366050.N234_37785 1.53e-53 187.0 COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,2VNNN@28216|Betaproteobacteria,1K24Z@119060|Burkholderiaceae 28216|Betaproteobacteria L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD - - - ko:K10979 ko03450,map03450 - - - ko00000,ko00001,ko03400 - - - Ku k59_186390_3 469378.Ccur_02880 2.18e-11 63.2 2EI48@1|root,33BVK@2|Bacteria,2GZ85@201174|Actinobacteria,4CY1Y@84998|Coriobacteriia 84998|Coriobacteriia - - - - - - - - - - - - - - - k59_103563_2 760568.Desku_1126 8.37e-66 222.0 COG1475@1|root,COG4725@1|root,COG1475@2|Bacteria,COG4725@2|Bacteria,1TT7N@1239|Firmicutes,24D10@186801|Clostridia 186801|Clostridia L ParB-like nuclease domain - - - - - - - - - - - - ParBc k59_30883_2 1070319.CAGGBEG34_330014 4.5e-25 100.0 COG2852@1|root,COG2852@2|Bacteria,1N2UX@1224|Proteobacteria,2VU7I@28216|Betaproteobacteria,1KA77@119060|Burkholderiaceae 28216|Betaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - - k59_91820_2 1692252.A0A0K1RL35_9CIRC 2.2e-91 280.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_17317_1 1121286.AUMT01000013_gene2672 2.31e-61 218.0 COG2518@1|root,COG2518@2|Bacteria 2|Bacteria O Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - Methyltransf_25,Methyltransf_31,rRNA_methylase k59_42622_2 1174529.WSI_05580 6.5e-22 99.8 COG0553@1|root,COG0553@2|Bacteria,1PXS8@1224|Proteobacteria,2UAZ5@28211|Alphaproteobacteria,4BED4@82115|Rhizobiaceae 28211|Alphaproteobacteria KL COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - - - - - - - - - - SNF2_N k59_54832_1 1122135.KB893135_gene598 3.96e-12 73.6 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,2TVGJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_176806_4 1165094.RINTHH_3920 3.65e-70 227.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_115300_3 1120936.KB907208_gene1107 1.24e-87 280.0 COG0209@1|root,COG0209@2|Bacteria,2IC1H@201174|Actinobacteria 201174|Actinobacteria F Ribonucleotide reductase, barrel domain - - - - - - - - - - - - Ribonuc_red_lgC k59_310296_3 1234888.K0A2J2_9VIRU 2.98e-54 190.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_103621_1 10704.B4UTY5_BP163 1.61e-44 155.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_103621_2 1403948.Q618_VCMC00001G0150 3.45e-11 68.9 29Y9W@1|root,30K3X@2|Bacteria,2HMZK@201174|Actinobacteria,4D7S5@85005|Actinomycetales 201174|Actinobacteria - - - - - - - - - - - - - - - k59_55489_1 1121927.GOHSU_16_01050 5.78e-07 51.6 COG1278@1|root,COG1278@2|Bacteria,2IR3P@201174|Actinobacteria,4GDXC@85026|Gordoniaceae 201174|Actinobacteria K 'Cold-shock' DNA-binding domain - - - - - - - - - - - - CSD k59_55489_2 1038869.AXAN01000028_gene1654 2.63e-34 136.0 COG4422@1|root,COG4422@2|Bacteria,1MXQI@1224|Proteobacteria,2VJP8@28216|Betaproteobacteria,1K05N@119060|Burkholderiaceae 28216|Betaproteobacteria S PFAM Gp37Gp68 family protein - - - - - - - - - - - - DUF5131 k59_55489_6 314230.DSM3645_08752 2.48e-153 451.0 COG0305@1|root,COG0305@2|Bacteria,2IXJT@203682|Planctomycetes 203682|Planctomycetes L Participates in initiation and elongation during chromosome replication - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_68019_1 460265.Mnod_6562 9.96e-67 214.0 COG4834@1|root,COG4834@2|Bacteria,1MZ5H@1224|Proteobacteria,2U21M@28211|Alphaproteobacteria,1JX7V@119045|Methylobacteriaceae 28211|Alphaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2184) - - - - - - - - - - - - DUF2184 k59_226286_3 1124991.MU9_2905 4.11e-94 292.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,1RY0J@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_249969_1 1538804.A0A088FAQ9_9CAUD 3.17e-44 155.0 4QFYS@10239|Viruses,4QUD0@28883|Caudovirales,4QMR9@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_115975_1 518635.BIFANG_02353 2.13e-12 68.6 COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria,4CZ31@85004|Bifidobacteriales 201174|Actinobacteria L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD k59_115975_2 720555.BATR1942_00815 2.33e-05 49.7 COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,4HBPI@91061|Bacilli,1ZB6W@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3048) C-terminal domain yerB - - - - - - - - - - - DUF3048,DUF3048_C k59_104104_1 1415780.JPOG01000001_gene1772 1.04e-57 192.0 2DCM2@1|root,32TZV@2|Bacteria,1NAGE@1224|Proteobacteria,1SMRS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_140706_2 1121937.AUHJ01000007_gene1934 8e-61 193.0 2DICG@1|root,302RI@2|Bacteria,1PVSB@1224|Proteobacteria,1STCY@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_335423_1 665956.HMPREF1032_00665 3.81e-31 125.0 28JED@1|root,2Z98K@2|Bacteria,1TW1U@1239|Firmicutes,24CFD@186801|Clostridia,3WNW0@541000|Ruminococcaceae 186801|Clostridia K Bacterial regulatory proteins, luxR family - - - - - - - - - - - - GerE k59_274388_1 1618241.A0A0C5I2I4_9CIRC 2.17e-19 90.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_177593_1 756277.A0A096VL04_9VIRU 7.7e-26 110.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage 10239|Viruses S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_128926_1 2003327.CAPSD_BPCHP 1.02e-14 79.7 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_359116_2 402612.FP2177 1.13e-68 226.0 COG0714@1|root,COG0714@2|Bacteria,4NJMT@976|Bacteroidetes,1HZMP@117743|Flavobacteriia 976|Bacteroidetes S AAA domain (dynein-related subfamily) - - 6.6.1.2 ko:K09882 ko00860,ko01100,map00860,map01100 - R05227 RC02000 ko00000,ko00001,ko01000 - - - AAA_5 k59_288387_1 929562.Emtol_0759 8.4e-13 74.7 COG0553@1|root,COG0553@2|Bacteria,4NKAA@976|Bacteroidetes,47MHC@768503|Cytophagia 976|Bacteroidetes KL COGs COG0553 Superfamily II DNA RNA helicase SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_371243_2 1618259.A0A0C5I2B5_9CIRC 9.92e-41 145.0 4QE84@10239|Viruses,4QUKR@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_371243_4 1618247.A0A0C5IMK7_9CIRC 6.08e-10 65.5 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_262513_2 504346.B5WZW3_BPPAJ 6.85e-15 74.7 4QCB0@10239|Viruses,4QX81@35237|dsDNA viruses no RNA stage,4QPFH@28883|Caudovirales,4QKQY@10699|Siphoviridae 10699|Siphoviridae S YqaJ-like viral recombinase domain - - - - - - - - - - - - - k59_262632_1 979533.F1D0R8_9CAUD 1.52e-30 122.0 4QZQB@35237|dsDNA viruses no RNA stage,4QTX7@28883|Caudovirales,4QP1A@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_289214_1 551895.B5AX97_9CAUD 1.47e-26 107.0 4QBHS@10239|Viruses,4QUVV@35237|dsDNA viruses no RNA stage,4QPT9@28883|Caudovirales,4QJCJ@10662|Myoviridae 10662|Myoviridae S DNA metabolic process - - - - - - - - - - - - - k59_7931_1 1692249.A0A0K1RLN8_9CIRC 1.7e-39 143.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_311849_2 1385658.U5KPZ6_9VIRU 6.94e-88 274.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_80924_1 1127516.H9C177_9CAUD 4.22e-10 61.2 4QAIJ@10239|Viruses,4QVZ9@35237|dsDNA viruses no RNA stage,4QPXI@28883|Caudovirales,4QHXZ@10662|Myoviridae 10662|Myoviridae S C-5 cytosine-specific DNA methylase - - - - - - - - - - - - - k59_105043_1 2003327.CAPSD_BPCHP 1.13e-41 155.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_94514_2 1162295.I1TRH6_9CAUD 3.84e-08 58.2 4QBY1@10239|Viruses,4QZSN@35237|dsDNA viruses no RNA stage,4QS4Q@28883|Caudovirales,4QK9A@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_69648_1 1500257.JQNM01000006_gene1746 8.71e-07 60.1 2DSWE@1|root,33HPD@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_19480_2 1234888.K0A2J2_9VIRU 6.41e-123 371.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_312567_1 742740.HMPREF9474_02303 1.31e-48 176.0 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia,221YV@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_349234_2 105154.Q9MBU0_9VIRU 2.19e-35 132.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_360475_3 1234888.K0A2J2_9VIRU 1.17e-142 425.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_167294_2 1609634.A0A0C5ANA6_9VIRU 1.51e-13 72.4 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_82668_1 1118055.CAGU01000028_gene111 1.72e-31 131.0 COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TPR1@1239|Firmicutes,25MTI@186801|Clostridia,22HYY@1570339|Peptoniphilaceae 186801|Clostridia S Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_95533_1 1282362.AEAC466_04465 9.04e-82 261.0 COG2304@1|root,COG2304@2|Bacteria,1QW8J@1224|Proteobacteria,2U1R3@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Trove domain-containing protein - - - - - - - - - - - - TROVE k59_313402_1 264462.Bd3266 9.46e-05 52.0 COG3210@1|root,COG3210@2|Bacteria,1NED3@1224|Proteobacteria,42WDX@68525|delta/epsilon subdivisions,2MTVC@213481|Bdellovibrionales,2WRDH@28221|Deltaproteobacteria 213481|Bdellovibrionales U cell wall surface anchor family protein - - - - - - - - - - - - Peptidase_S74 k59_143463_2 742740.HMPREF9474_02267 1.87e-66 211.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia,221N8@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_373828_2 1692244.A0A0K1RLR5_9CIRC 1.87e-90 276.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_313573_1 246197.MXAN_1208 1.83e-48 170.0 COG0863@1|root,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_252556_1 1172188.KB911820_gene2858 3.5e-15 80.9 COG0739@1|root,COG0741@1|root,COG0739@2|Bacteria,COG0741@2|Bacteria,2IGMV@201174|Actinobacteria 201174|Actinobacteria M Transglycosylase SLT domain - - - - - - - - - - - - PG_binding_1,SLT,T7SS_ESX_EspC k59_326217_3 1618251.A0A0C5I2L8_9CIRC 3.91e-10 68.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_373832_1 706587.Desti_3664 1e-06 55.1 COG0438@1|root,COG0438@2|Bacteria,1QXXB@1224|Proteobacteria,42ZQB@68525|delta/epsilon subdivisions,2WV4A@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Methyltransferase domain - - - - - - - - - - - - Methyltransf_24 k59_314599_1 1215092.PA6_009_00300 4.13e-53 180.0 28JC4@1|root,2Z96S@2|Bacteria,1RI8W@1224|Proteobacteria,1S6FI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S P22 coat protein-protein 5 domain protein - - - - - - - - - - - - - k59_119500_5 526227.Mesil_3191 1.55e-11 63.5 COG1555@1|root,COG1555@2|Bacteria 2|Bacteria L photosystem II stabilization comEA - 2.4.1.21 ko:K00703,ko:K02237,ko:K02238 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00429,M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003,ko02044 3.A.11.1,3.A.11.2 GT5 - HHH_3,PLDc_2,SLBB k59_119500_9 52644.XP_010571021.1 2.88e-14 76.3 KOG2401@1|root,KOG2401@2759|Eukaryota,39R9J@33154|Opisthokonta,3B9DR@33208|Metazoa,3CRA5@33213|Bilateria,489X7@7711|Chordata,4914G@7742|Vertebrata,4GI7B@8782|Aves 33208|Metazoa L NEDD4-binding protein 2-like 2 N4BP2L2 GO:0000122,GO:0001701,GO:0001824,GO:0002682,GO:0002683,GO:0002684,GO:0003674,GO:0003712,GO:0003714,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006355,GO:0006357,GO:0007275,GO:0008150,GO:0008284,GO:0009790,GO:0009792,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017053,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032501,GO:0032502,GO:0032991,GO:0042127,GO:0043009,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045595,GO:0045596,GO:0045892,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048856,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0051094,GO:0051171,GO:0051172,GO:0051239,GO:0051240,GO:0051241,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0072091,GO:0080090,GO:0140110,GO:1901532,GO:1901533,GO:1902033,GO:1902035,GO:1902036,GO:1902037,GO:1902679,GO:1903506,GO:1903507,GO:1903706,GO:1903707,GO:1903708,GO:2000026,GO:2000112,GO:2000113,GO:2000648,GO:2000736,GO:2000737,GO:2001141 - - - - - - - - - - AAA_33,Smr k59_21482_1 269797.Mbar_A3575 2.36e-11 73.6 COG3291@1|root,arCOG02515@1|root,arCOG02527@1|root,arCOG02510@2157|Archaea,arCOG02515@2157|Archaea,arCOG02527@2157|Archaea 2157|Archaea O PFAM PKD domain containing protein - - - - - - - - - - - - CARDB,CBM_6,CHB_HEX_C_1,DUF3344,NosD,PKD k59_107823_1 691965.D4P7I3_9CAUD 1.83e-199 598.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_181375_2 1123508.JH636439_gene1948 5.97e-18 81.6 2DRCN@1|root,33B89@2|Bacteria,2J3XX@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_96836_1 1692242.A0A0K1RKZ2_9CIRC 3.98e-28 112.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_96836_2 1692257.A0A0K1RL39_9CIRC 1.78e-30 117.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_339188_1 1096930.L284_17150 8.55e-22 93.2 2ATMD@1|root,31J5V@2|Bacteria,1RH31@1224|Proteobacteria,2UBNT@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tail tubular protein - - - - - - - - - - - - Tube k59_277814_1 592028.GCWU000321_01359 3.57e-114 352.0 COG0553@1|root,COG0553@2|Bacteria,1TP2C@1239|Firmicutes,4H2V4@909932|Negativicutes 909932|Negativicutes KL DEAD-like helicases superfamily - - - - - - - - - - - - N6_N4_Mtase k59_132733_1 1129794.C427_1458 0.000631 42.7 COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria,468BM@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Belongs to the N-Me-Phe pilin family ppdD GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - ko:K02650,ko:K02682 ko02020,map02020 - - - ko00000,ko00001,ko02035,ko02044 3.A.15.2 - - N_methyl,Pilin k59_35409_1 1131814.JAFO01000001_gene2921 0.000543 47.8 COG0457@1|root,COG0457@2|Bacteria,1MUZK@1224|Proteobacteria,2TS0U@28211|Alphaproteobacteria,3F0F9@335928|Xanthobacteraceae 28211|Alphaproteobacteria M TPR repeat - - - - - - - - - - - - Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8 k59_10330_1 1082933.MEA186_01041 3.08e-24 103.0 2CDQ7@1|root,2Z7KV@2|Bacteria,1MY2D@1224|Proteobacteria,2TR92@28211|Alphaproteobacteria,43J4F@69277|Phyllobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_265272_2 981335.G4W934_9CAUD 2.3e-56 183.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales 28883|Caudovirales S N-methyltransferase activity - - - - - - - - - - - - - k59_303047_2 1173263.Syn7502_03247 2.13e-09 60.8 COG4122@1|root,COG4122@2|Bacteria,1G8BJ@1117|Cyanobacteria 1117|Cyanobacteria S O-methyltransferase activity - - - - - - - - - - - - Methyltransf_24 k59_21489_3 1115512.EH105704_01_02300 5.18e-70 228.0 COG1659@1|root,COG1659@2|Bacteria,1R0IH@1224|Proteobacteria,1T4F0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Linocin_M18 bacteriocin protein - - - - - - - - - - - - - k59_157025_2 1205680.CAKO01000006_gene3232 6.4e-15 79.3 2DTAA@1|root,33JEH@2|Bacteria,1NFFI@1224|Proteobacteria,2UFJK@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_327810_1 794903.OPIT5_03875 1.38e-37 140.0 COG0863@1|root,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - 2.1.1.72 ko:K03497,ko:K07316 - - - - ko00000,ko01000,ko02048,ko03000,ko03036,ko04812 - - - N6_N4_Mtase,ParBc k59_120248_3 77635.BISU_1950 3.57e-05 49.7 COG1475@1|root,COG1475@2|Bacteria,2HTYC@201174|Actinobacteria,4D0GC@85004|Bifidobacteriales 201174|Actinobacteria K ParB-like nuclease domain - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_375809_3 105154.Q9MBU6_9VIRU 1.22e-127 382.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_47986_1 1210884.HG799466_gene12694 8.88e-29 107.0 2E6JI@1|root,3316K@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_120312_1 1609634.A0A0C5AFV4_9VIRU 2.43e-55 189.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_327896_2 1121441.AUCX01000022_gene755 8.46e-14 71.2 2BI81@1|root,32CDB@2|Bacteria,1PZE3@1224|Proteobacteria,436BR@68525|delta/epsilon subdivisions,2X0WV@28221|Deltaproteobacteria,2MDMU@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_24134_2 1609634.A0A0C5ANA6_9VIRU 3.26e-08 60.5 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_24134_5 1165094.RINTHH_3920 3.04e-70 227.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_24134_6 145579.C_BPPHM 6.62e-11 61.2 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_24134_7 1609634.A0A0C5AFV4_9VIRU 2.84e-108 334.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_364434_1 596152.DesU5LDRAFT_2406 4.87e-28 125.0 COG3378@1|root,COG3378@2|Bacteria,1MV7I@1224|Proteobacteria,42QNW@68525|delta/epsilon subdivisions,2WMSE@28221|Deltaproteobacteria,2M9CB@213115|Desulfovibrionales 28221|Deltaproteobacteria L primase, P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N k59_388379_1 1618260.A0A0C5I2C5_9CIRC 6.03e-32 123.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388379_3 1618260.A0A0C5I2C5_9CIRC 9.71e-15 75.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388380_1 1611039.A0A0C5C3Z3_9CIRC 1.47e-43 154.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_191552_1 1506572.A0A097ZPG0_9CIRC 1.97e-32 126.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388382_1 1618248.A0A0C5IB82_9CIRC 1.43e-21 94.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388382_2 1618237.A0A0C5IMG6_9CIRC 1.76e-13 74.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388386_1 1618247.A0A0C5IMK7_9CIRC 1.43e-07 57.8 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_388389_1 1380894.S5TR92_9CIRC 7.25e-46 162.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388392_2 1692244.A0A0K1RLR5_9CIRC 7.49e-43 154.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_191622_1 1340829.S5Y5F0_9CAUD 2.39e-45 168.0 4QNA2@10699|Siphoviridae 10699|Siphoviridae S AAA domain - - - - - - - - - - - - - k59_388394_1 1574422.A0A0A1ENW9_9CIRC 1.04e-41 152.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388394_3 1379711.S5SYC9_9CIRC 3.36e-10 60.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_122373_2 1440774.Y900_025690 1.5e-24 102.0 COG3000@1|root,COG3000@2|Bacteria,2HR3N@201174|Actinobacteria,234PY@1762|Mycobacteriaceae 201174|Actinobacteria I Fatty acid hydroxylase - - - - - - - - - - - - FA_hydroxylase k59_85829_1 1385658.U5KPZ6_9VIRU 1.27e-110 337.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_134367_1 1692250.A0A0K1RLR1_9CIRC 4.35e-10 60.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_61745_1 1618260.A0A0C5I2C5_9CIRC 9.97e-46 160.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_219728_1 1341151.ASZU01000008_gene1358 1.53e-08 62.4 COG1475@1|root,COG1475@2|Bacteria,1TP0I@1239|Firmicutes,4HAC6@91061|Bacilli,27B56@186824|Thermoactinomycetaceae 91061|Bacilli K ParB-like nuclease domain noc - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_170857_1 234267.Acid_2246 6.54e-61 197.0 COG2089@1|root,COG2089@2|Bacteria,3Y39R@57723|Acidobacteria 57723|Acidobacteria M PFAM N-acetylneuraminic acid synthase, N-terminal - - 2.5.1.56 ko:K01654 ko00520,ko01100,map00520,map01100 - R01804,R04435 RC00159 ko00000,ko00001,ko01000 - - - NeuB k59_195219_2 105154.Q9MBU6_9VIRU 5.79e-107 329.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_377605_1 1165094.RINTHH_3920 4.96e-36 134.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_377605_3 1385658.U5KPZ6_9VIRU 6.45e-200 575.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_377605_5 1986029.Q9MBM6_9VIRU 1.65e-20 89.7 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_25079_1 1006006.Mcup_1830 2.16e-31 122.0 COG0451@1|root,arCOG04762@2157|Archaea,2XQ3Z@28889|Crenarchaeota 28889|Crenarchaeota M PFAM NAD dependent epimerase dehydratase family - - - - - - - - - - - - Epimerase,GDP_Man_Dehyd k59_12799_8 105154.Q9MBU6_9VIRU 5.45e-97 300.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_280589_1 266779.Meso_0205 2.28e-19 90.5 COG3206@1|root,COG3206@2|Bacteria,1ND5H@1224|Proteobacteria,2UIQZ@28211|Alphaproteobacteria,43P6G@69277|Phyllobacteriaceae 28211|Alphaproteobacteria M protein involved in exopolysaccharide biosynthesis - - - - - - - - - - - - - k59_73827_1 1618248.A0A0C5IB82_9CIRC 1.25e-49 171.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_110242_2 1692250.A0A0K1RLR1_9CIRC 1.14e-51 175.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_872_4 691965.D4P7D3_9CAUD 4.52e-158 458.0 4QAYV@10239|Viruses,4QUZ7@35237|dsDNA viruses no RNA stage,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - k59_98057_2 1379715.S5TMW6_9CIRC 3.04e-50 174.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_98057_3 1692249.A0A0K1RLN8_9CIRC 2.38e-27 107.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_134397_1 716928.AJQT01000109_gene1217 4.89e-36 128.0 2FEUE@1|root,346TC@2|Bacteria,1MZPB@1224|Proteobacteria,2UC4Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_13118_3 1341151.ASZU01000004_gene247 4.34e-08 61.6 COG3409@1|root,COG5632@1|root,COG3409@2|Bacteria,COG5632@2|Bacteria,1V7KT@1239|Firmicutes,4HJ9N@91061|Bacilli,27BVQ@186824|Thermoactinomycetaceae 91061|Bacilli M Ami_2 - - - - - - - - - - - - Amidase_2,DUF3597,PG_binding_1,SH3_5,SPOR k59_378104_7 943335.F4N9T0_9CAUD 1.6e-52 185.0 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QPEB@28883|Caudovirales,4QP3P@10744|Podoviridae 10744|Podoviridae S phosphoprotein phosphatase activity - - - - - - - - - - - - - k59_317541_1 1192759.AKIB01000023_gene2894 3.02e-24 107.0 2EXSU@1|root,33R23@2|Bacteria,1NS77@1224|Proteobacteria,2UR4M@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_220438_1 1788454.A0A190WHE4_9CIRC 3.62e-67 217.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_13167_1 411460.RUMTOR_02024 2.24e-30 118.0 2A0KC@1|root,30NQJ@2|Bacteria,1V3K4@1239|Firmicutes,24HYK@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_354005_1 419610.Mext_4385 7.86e-09 56.2 2CJW6@1|root,32SAX@2|Bacteria,1N3WF@1224|Proteobacteria,2USGV@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_354005_3 156889.Mmc1_2604 2.55e-45 164.0 COG1475@1|root,COG4725@1|root,COG1475@2|Bacteria,COG4725@2|Bacteria,1R553@1224|Proteobacteria,2TRP6@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT Belongs to the MT-A70-like family - - - - - - - - - - - - MT-A70 k59_268741_1 186617.M9M8L2_9VIRU 2.86e-41 159.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_244221_3 1121459.AQXE01000001_gene2744 3.03e-16 87.8 COG5164@1|root,COG5164@2|Bacteria,1N2FU@1224|Proteobacteria,42WNM@68525|delta/epsilon subdivisions,2WRNC@28221|Deltaproteobacteria 28221|Deltaproteobacteria K Collagen triple helix repeat (20 copies) - - - - - - - - - - - - - k59_37881_2 1165094.RINTHH_3920 3.67e-56 191.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_317545_1 1417599.U6C7Z1_9CAUD 3.13e-24 112.0 4QD9Y@10239|Viruses,4QUXQ@35237|dsDNA viruses no RNA stage,4QTPE@28883|Caudovirales,4QNY4@10744|Podoviridae 10744|Podoviridae S Terminase-like family - - - - - - - - - - - - - k59_111437_4 1416759.AYMR01000009_gene3060 7.2e-21 92.0 COG4675@1|root,COG4675@2|Bacteria,2IIYR@201174|Actinobacteria 201174|Actinobacteria S Phage Tail Collar Domain - - - - - - - - - - - - Collar k59_99272_2 1732201.A0A0N9N7I3_9CIRC 2.14e-12 70.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_209021_1 1094508.Tsac_2145 1.28e-06 56.2 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,42FDS@68295|Thermoanaerobacterales 186801|Clostridia L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_318314_1 1121106.JQKB01000013_gene5429 4.22e-16 83.2 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,2TT3N@28211|Alphaproteobacteria,2JQ8P@204441|Rhodospirillales 204441|Rhodospirillales S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_196613_1 1027273.GZ77_20520 4.35e-84 267.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1RP8Z@1236|Gammaproteobacteria,1XH6H@135619|Oceanospirillales 135619|Oceanospirillales S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_38400_1 999141.GME_16377 2.84e-55 197.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1R97W@1224|Proteobacteria 1224|Proteobacteria D Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_305998_2 105154.Q9MBU6_9VIRU 3.38e-205 588.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_305998_5 145579.REP_BPPHM 9.5e-25 109.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_135631_1 1463887.KL589968_gene7425 9.18e-07 50.8 2AU1G@1|root,31JMM@2|Bacteria,2IJKK@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_257297_1 186617.M9M8L2_9VIRU 3.8e-91 284.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_318316_1 1121020.JIAG01000013_gene1286 6e-15 75.1 COG0739@1|root,COG0739@2|Bacteria,2GM7Q@201174|Actinobacteria,1WCA7@1268|Micrococcaceae 201174|Actinobacteria M Peptidase family M23 mepA - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 k59_318316_2 1031288.AXAA01000003_gene1627 3.17e-06 49.7 2EUFA@1|root,33MXK@2|Bacteria,1VQFP@1239|Firmicutes,24S0X@186801|Clostridia,36N6B@31979|Clostridiaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_330420_1 755731.Clo1100_3573 8.91e-12 67.0 292XD@1|root,2ZQEV@2|Bacteria,1V48I@1239|Firmicutes,24GZD@186801|Clostridia,36I9N@31979|Clostridiaceae 186801|Clostridia S COG NOG18825 non supervised orthologous group - - - - - - - - - - - - - k59_318323_1 1219049.SP5_069_01280 2.06e-59 192.0 2DRE2@1|root,33BCC@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_26308_1 1385658.U5KNR1_9VIRU 5.39e-51 174.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_282280_1 1121861.KB899914_gene2048 6.42e-62 212.0 COG0209@1|root,COG0209@2|Bacteria,1N0E3@1224|Proteobacteria,2UQM4@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Ribonucleotide reductase, barrel domain - - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - Ribonuc_red_lgC k59_342304_1 1121456.ATVA01000015_gene2512 1.96e-18 87.0 2C9JF@1|root,32RPD@2|Bacteria,1N8CG@1224|Proteobacteria,42REW@68525|delta/epsilon subdivisions,2WNQ1@28221|Deltaproteobacteria,2MB30@213115|Desulfovibrionales 28221|Deltaproteobacteria S ERF superfamily - - - - - - - - - - - - ERF k59_330437_1 1123508.JH636446_gene6442 2.23e-28 107.0 2DRCN@1|root,33B89@2|Bacteria,2J3XX@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_13601_1 7209.EFO25451.1 1.63e-07 55.5 2EWQP@1|root,2SYH6@2759|Eukaryota 2759|Eukaryota S RNA helicase - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_13601_2 1618248.A0A0C5IB82_9CIRC 3.76e-23 100.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_87205_1 759938.F5BSB4_9CIRC 2.8e-16 82.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_232937_7 1142394.PSMK_02910 6.59e-52 172.0 COG0717@1|root,COG0717@2|Bacteria,2IZ2N@203682|Planctomycetes 203682|Planctomycetes F dUTPase - - 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 - - - dUTPase k59_232937_13 227086.JGI_V11_89639 5.18e-15 83.6 COG0749@1|root,KOG0950@2759|Eukaryota 2759|Eukaryota L plastid DNA replication POL1A - 2.7.7.7 ko:K02335,ko:K02349 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DEAD,DNA_pol_A,Helicase_C k59_14056_1 1234888.K0A2J2_9VIRU 4.55e-22 98.2 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_245504_1 706587.Desti_2304 5.17e-23 107.0 COG3378@1|root,COG3378@2|Bacteria,1MV7I@1224|Proteobacteria,42QE4@68525|delta/epsilon subdivisions,2WM1X@28221|Deltaproteobacteria 28221|Deltaproteobacteria L Phage plasmid primase, P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,Toprim_2,zf-CHC2 k59_63775_3 34506.g5911 1.2e-40 156.0 COG1875@1|root,2S7WC@2759|Eukaryota,3AIEB@33154|Opisthokonta,3BXHE@33208|Metazoa,3DD55@33213|Bilateria 33208|Metazoa T PhoH-like protein - - - - - - - - - - - - PhoH k59_294421_1 1423144.Gal_02262 1.04e-47 173.0 2C5GI@1|root,2Z8C1@2|Bacteria,1R8XM@1224|Proteobacteria,2TUME@28211|Alphaproteobacteria 28211|Alphaproteobacteria S P22 coat protein - gene protein 5 - - - - - - - - - - - - P22_CoatProtein k59_294421_3 247633.GP2143_03598 0.000367 47.4 COG0810@1|root,COG2063@1|root,COG5183@1|root,COG0810@2|Bacteria,COG2063@2|Bacteria,COG5183@2|Bacteria,1RM1B@1224|Proteobacteria,1S718@1236|Gammaproteobacteria,1JAFZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria N Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - - - - - - - - - - - k59_294421_4 744980.TRICHSKD4_2781 3.29e-10 65.5 COG0863@1|root,COG0863@2|Bacteria,1R7RR@1224|Proteobacteria 1224|Proteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_245584_1 1449126.JQKL01000003_gene1702 5.22e-26 101.0 COG4570@1|root,COG4570@2|Bacteria,1VFJ9@1239|Firmicutes,24NSB@186801|Clostridia 186801|Clostridia L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC - - - - - - - - - - - - RusA k59_269921_1 386793.Q0E5Y0_9CAUD 2.37e-47 167.0 4QARC@10239|Viruses,4QV4E@35237|dsDNA viruses no RNA stage,4QPDS@28883|Caudovirales,4QP0H@10744|Podoviridae 10744|Podoviridae S nucleic acid binding - - - - - - - - - - - - - k59_355205_1 269796.Rru_A3313 1.56e-28 117.0 28IR7@1|root,2Z8QR@2|Bacteria,1PBTP@1224|Proteobacteria,2U248@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_257928_1 1380367.JIBC01000006_gene311 2.65e-18 96.3 2DNH7@1|root,32XH1@2|Bacteria,1RHPW@1224|Proteobacteria,2UIT5@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_331773_3 1234888.K0A2J2_9VIRU 3.47e-110 339.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_294996_1 1618248.A0A0C5IB82_9CIRC 8.72e-57 192.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_355797_1 105154.Q9MBU0_9VIRU 2.21e-16 79.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_270530_1 685782.O99_00923 4.29e-42 162.0 COG3170@1|root,COG3170@2|Bacteria,1R69E@1224|Proteobacteria,2U3B9@28211|Alphaproteobacteria,48TPA@772|Bartonellaceae 28211|Alphaproteobacteria NU Phage P22-like portal protein - - - - - - - - - - - - P22_portal k59_367611_1 1173762.S4TT67_9CAUD 1.62e-55 190.0 4QCT5@10239|Viruses,4QYJH@35237|dsDNA viruses no RNA stage,4QTPG@28883|Caudovirales,4QNK2@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_367611_2 655097.C8ZKH8_9CAUD 1.23e-78 246.0 4QGGR@10239|Viruses,4QZHR@35237|dsDNA viruses no RNA stage,4QUGZ@28883|Caudovirales,4QNY3@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_112690_2 105154.Q9MBU6_9VIRU 2.73e-24 102.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_125253_3 520999.PROVALCAL_01867 2.06e-26 101.0 COG3179@1|root,COG3179@2|Bacteria,1RE8K@1224|Proteobacteria,1S4U8@1236|Gammaproteobacteria,3Z9BP@586|Providencia 1236|Gammaproteobacteria S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Peptidase_M15_4 k59_27737_3 1004785.AMBLS11_00405 1.68e-34 148.0 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,1RNAN@1236|Gammaproteobacteria,4657B@72275|Alteromonadaceae 1236|Gammaproteobacteria L type III restriction enzyme, res subunit - - - - - - - - - - - - DUF3427,Helicase_C,Methyltransf_25,PLDc_2,ResIII k59_136901_2 1122599.AUGR01000001_gene288 1.19e-57 187.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,1SQ0T@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_355804_1 1089550.ATTH01000001_gene2300 6.42e-12 72.4 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1FJ68@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_3691_1 10704.B4UTY5_BP163 6.94e-11 64.3 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_136903_1 1385658.U5KPZ6_9VIRU 9.1e-53 183.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_270546_1 479434.Sthe_1313 9.43e-37 134.0 2C5T0@1|root,337HV@2|Bacteria,2G9CN@200795|Chloroflexi,27Y76@189775|Thermomicrobia 189775|Thermomicrobia - - - - - - - - - - - - - - - k59_295114_2 1618243.A0A0C5IAV0_9CIRC 1.67e-37 136.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_112700_1 525255.HMPREF0077_0417 4.16e-24 103.0 COG3723@1|root,COG3723@2|Bacteria,1UNDF@1239|Firmicutes,24CI5@186801|Clostridia,22JGH@1570339|Peptoniphilaceae 186801|Clostridia L RecT family recT - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_88576_1 691965.D4P7I3_9CAUD 2.56e-137 430.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_100805_2 1385658.U5KNR1_9VIRU 5.03e-16 79.3 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_210418_1 438753.AZC_3588 1.27e-54 187.0 28MSK@1|root,2ZB0X@2|Bacteria,1R7CY@1224|Proteobacteria,2U2MY@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_89312_3 288000.BBta_3746 1.68e-07 53.9 COG2304@1|root,COG2304@2|Bacteria,1QW8J@1224|Proteobacteria,2U1R3@28211|Alphaproteobacteria,3JRT6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Trove domain-containing protein - - - - - - - - - - - - TROVE k59_223147_1 247634.GPB2148_914 7.18e-05 45.8 COG0582@1|root,COG0582@2|Bacteria,1P1R9@1224|Proteobacteria,1RRV0@1236|Gammaproteobacteria,1J9F0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Phage integrase - - - - - - - - - - - - Phage_integrase k59_149907_5 388051.AUFE01000035_gene4020 3.2e-81 264.0 COG4653@1|root,COG4653@2|Bacteria 2|Bacteria G Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_149907_7 1397284.AYMN01000081_gene2459 9.12e-156 461.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1RP8Z@1236|Gammaproteobacteria,402XD@613|Serratia 1236|Gammaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_149907_8 522373.Smlt1882 1.91e-178 514.0 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1MVH7@1224|Proteobacteria,1S09Z@1236|Gammaproteobacteria,1X9IF@135614|Xanthomonadales 135614|Xanthomonadales L ParB-like nuclease domain - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_308064_2 99598.Cal7507_1583 1.76e-85 275.0 COG0305@1|root,COG0305@2|Bacteria,1G0R8@1117|Cyanobacteria,1HJAT@1161|Nostocales 1117|Cyanobacteria L Participates in initiation and elongation during chromosome replication dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3 k59_101511_1 1609634.A0A0C5ANA6_9VIRU 3.49e-05 50.4 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_101511_2 1609634.A0A0C5AFV4_9VIRU 1.19e-156 464.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_101511_3 105154.Q9MBT9_9VIRU 2.82e-13 66.2 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_101511_4 1385658.U5KNR1_9VIRU 1.96e-71 231.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_126027_6 392499.Swit_2199 2.95e-50 173.0 COG0338@1|root,COG0338@2|Bacteria,1P85S@1224|Proteobacteria,2TS2X@28211|Alphaproteobacteria,2K2FK@204457|Sphingomonadales 204457|Sphingomonadales L D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_126027_11 1517681.HW45_18920 2.27e-71 230.0 COG4227@1|root,COG4227@2|Bacteria,1MU8I@1224|Proteobacteria,1RNU7@1236|Gammaproteobacteria,1XVNE@135623|Vibrionales 135623|Vibrionales L Domain of unknown function (DUF1738) - - - - - - - - - - - - DUF1738 k59_101639_1 369723.Strop_0517 2.91e-51 172.0 2EES9@1|root,338JX@2|Bacteria,2H5MY@201174|Actinobacteria 201174|Actinobacteria L RNase_H superfamily - - - - - - - - - - - - RNase_H_2 k59_332563_2 1100720.ALKN01000018_gene1742 6.22e-56 187.0 28HHC@1|root,2Z7T2@2|Bacteria,1PZ57@1224|Proteobacteria 1224|Proteobacteria S AAA domain - - - - - - - - - - - - AAA_24 k59_235015_1 411460.RUMTOR_01339 2.73e-15 73.6 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_90163_2 472759.Nhal_0999 1.3e-09 57.0 COG5471@1|root,COG5471@2|Bacteria,1NMSP@1224|Proteobacteria,1SHMP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterized conserved protein (DUF2190) - - - - - - - - - - - - DUF2190 k59_247735_3 443255.SCLAV_1208 3.9e-12 71.6 COG3409@1|root,COG3409@2|Bacteria,2GR1Q@201174|Actinobacteria 201174|Actinobacteria M N-Acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2,LAGLIDADG_3,PG_binding_1 k59_296520_1 1072685.IX83_00105 7.6e-08 58.9 COG1216@1|root,COG1216@2|Bacteria,1R554@1224|Proteobacteria,2VKBV@28216|Betaproteobacteria 28216|Betaproteobacteria S Glycosyl transferase, family 2 - - - - - - - - - - - - - k59_357059_1 106648.BBLJ01000014_gene1425 1.24e-10 66.6 COG3206@1|root,COG3206@2|Bacteria,1ND5H@1224|Proteobacteria,1RNXC@1236|Gammaproteobacteria,3NSVB@468|Moraxellaceae 1236|Gammaproteobacteria M protein involved in exopolysaccharide biosynthesis - - - - - - - - - - - - Rad52_Rad22 k59_138412_1 1123228.AUIH01000006_gene2323 4.48e-40 139.0 COG2131@1|root,COG2131@2|Bacteria,1PNTJ@1224|Proteobacteria,1THD6@1236|Gammaproteobacteria,1XQDF@135619|Oceanospirillales 135619|Oceanospirillales F MafB19-like deaminase - - - - - - - - - - - - dCMP_cyt_deam_1 k59_199273_1 439496.RBY4I_316 3.21e-17 87.0 COG3598@1|root,COG4643@1|root,COG3598@2|Bacteria,COG4643@2|Bacteria,1R6M4@1224|Proteobacteria,2U1V0@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction - - - ko:K06919 - - - - ko00000 - - - PriCT_2,Prim-Pol k59_90252_3 35703.DQ02_13795 2.6e-27 106.0 COG3926@1|root,COG3926@2|Bacteria,1QV3R@1224|Proteobacteria,1T276@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Glycosyl hydrolase 108 - - - - - - - - - - - - CHAP k59_296610_1 1458716.W8FTA2_9CAUD 7.01e-34 134.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_29582_1 1141137.K4F7X8_9CAUD 7.89e-33 130.0 4QFN8@10239|Viruses,4QYWE@35237|dsDNA viruses no RNA stage,4QS52@28883|Caudovirales,4QP1K@10744|Podoviridae 10744|Podoviridae S metal ion binding - - - - - - - - - - - - - k59_163046_3 1385658.U5KPZ6_9VIRU 1.04e-102 322.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_296613_2 340099.Teth39_1789 9.28e-17 82.8 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia,42FCZ@68295|Thermoanaerobacterales 186801|Clostridia L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k59_65940_1 997296.PB1_00360 1.23e-31 124.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups glgP - 2.4.1.1,2.4.1.11 ko:K16153 ko00500,ko01100,ko01110,map00500,map01100,map01110 - R00292,R02111 RC00005 ko00000,ko00001,ko01000,ko01003 - GT3,GT35 - DUF3417,Glyco_trans_1_2,Glyco_transf_4,Glyco_transf_8,Glycogen_syn,Glycos_transf_1,Glycos_transf_2,Phosphorylase k59_41144_2 666686.B1NLA3E_06895 2.14e-06 50.4 2CDF4@1|root,32RXN@2|Bacteria,1VACE@1239|Firmicutes,4HKM4@91061|Bacilli,1ZHZZ@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1360) - - - - - - - - - - - - DUF1360 k59_369120_2 1415780.JPOG01000001_gene1170 0.0002 45.4 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1X48C@135614|Xanthomonadales 135614|Xanthomonadales L dna polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k59_345174_1 1609634.A0A0C5AFV4_9VIRU 9.65e-37 144.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_126726_1 999141.GME_16357 4.47e-18 95.1 2DZHM@1|root,32VAY@2|Bacteria,1N0DC@1224|Proteobacteria,1SP9I@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_163047_1 1005058.UMN179_00831 1.16e-10 71.6 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1Y7ZN@135625|Pasteurellales 135625|Pasteurellales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_321227_5 1122201.AUAZ01000017_gene2949 7.98e-54 190.0 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,1RXX2@1236|Gammaproteobacteria,46B9P@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N k59_321227_7 411464.DESPIG_01861 5.51e-49 175.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,42QA8@68525|delta/epsilon subdivisions,2WJBW@28221|Deltaproteobacteria,2M8NS@213115|Desulfovibrionales 28221|Deltaproteobacteria S PFAM ATPase associated with various cellular activities - - - - - - - - - - - - AAA_3,AAA_5 k59_321227_8 1540097.A0A0A0YU43_9CAUD 2.05e-45 166.0 4QBMV@10239|Viruses,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_345177_2 428125.CLOLEP_01409 1.23e-44 160.0 COG4626@1|root,COG4626@2|Bacteria,1TT9I@1239|Firmicutes,24AFK@186801|Clostridia,3WNF4@541000|Ruminococcaceae 186801|Clostridia S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_296628_1 691965.D4P7I3_9CAUD 1.47e-63 222.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_259833_1 1609634.A0A0C5AFT2_9VIRU 6.59e-88 271.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_259833_4 1609634.A0A0C5AFV4_9VIRU 1.94e-245 690.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_66613_3 1788447.A0A190WHJ9_9CIRC 3.13e-99 299.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_127374_3 926549.KI421517_gene2362 3.27e-53 177.0 2C0VP@1|root,32ZQ9@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_224758_1 1117943.SFHH103_00150 1.81e-14 84.0 2DPZ1@1|root,3340X@2|Bacteria,1R2EE@1224|Proteobacteria,2TZIB@28211|Alphaproteobacteria,4BP2Q@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_163755_1 1574422.A0A0A1ENW9_9CIRC 7.7e-21 94.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_272961_3 935837.JAEK01000054_gene1465 7.15e-31 130.0 COG4373@1|root,COG4373@2|Bacteria,1TQNK@1239|Firmicutes,4HDES@91061|Bacilli,1ZBVH@1386|Bacillus 91061|Bacilli S Mu-like prophage FluMu protein gp28 gp17a - - - - - - - - - - - Terminase_6,Terminase_6C k59_176044_1 1234888.K0A2J2_9VIRU 4.81e-71 235.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_200082_1 186617.M9M8L2_9VIRU 4.32e-124 372.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_345919_1 1234888.K0A2J2_9VIRU 1.59e-59 202.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_345919_2 1986029.Q9MBM3_9VIRU 8.31e-21 97.4 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_321902_4 1123355.JHYO01000035_gene586 6.67e-80 266.0 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,2TT3N@28211|Alphaproteobacteria,370PW@31993|Methylocystaceae 28211|Alphaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_321902_8 1089552.KI911559_gene3374 3.55e-93 283.0 28HS3@1|root,2Z7ZE@2|Bacteria,1QH9A@1224|Proteobacteria,2TVB0@28211|Alphaproteobacteria,2JPPD@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_139280_9 290402.Cbei_3962 2.34e-13 72.0 COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia,36FEY@31979|Clostridiaceae 186801|Clostridia O Subtilase family isp - 3.4.21.62 ko:K01342,ko:K13275,ko:K13277 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - Peptidase_S8 k59_54210_1 585503.HMPREF7545_1731 7.71e-23 103.0 COG5323@1|root,COG5323@2|Bacteria,1UMAZ@1239|Firmicutes,4H9ED@909932|Negativicutes 909932|Negativicutes S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_41957_4 1437448.AZRT01000050_gene159 3.61e-42 154.0 2DECN@1|root,2ZMDM@2|Bacteria,1P6WS@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_212915_1 1692250.A0A0K1RLR1_9CIRC 2.19e-22 94.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_225722_1 1122214.AQWH01000002_gene4211 4.72e-24 107.0 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,2TQWC@28211|Alphaproteobacteria,2PJ9J@255475|Aurantimonadaceae 28211|Alphaproteobacteria L UvrD-like helicase C-terminal domain recD - 3.1.11.5 ko:K01144 - - - - ko00000,ko01000 - - - AAA_30,UvrD_C_2 k59_346814_1 1282876.BAOK01000002_gene196 1.23e-34 133.0 COG0438@1|root,COG0438@2|Bacteria,1QY7T@1224|Proteobacteria,2TXJ6@28211|Alphaproteobacteria,4BTGN@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria M Sulfotransferase family - - 2.8.2.1 ko:K01014 ko05204,map05204 - R01242 RC00007,RC00128 ko00000,ko00001,ko01000 - - - Sulfotransfer_1 k59_140199_1 1123487.KB892865_gene1391 1.13e-78 252.0 COG0553@1|root,COG0553@2|Bacteria,1PN7I@1224|Proteobacteria,2VP2N@28216|Betaproteobacteria 28216|Betaproteobacteria L Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair - - - - - - - - - - - - SNF2_N k59_322815_1 1618241.A0A0C5I2I4_9CIRC 6.45e-85 260.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_152534_1 1692249.A0A0K1RLN8_9CIRC 1.48e-20 91.3 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_358594_7 1234888.K0A2J2_9VIRU 6.78e-57 196.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_334801_1 428125.CLOLEP_01407 3.34e-27 103.0 2DHA9@1|root,32U8X@2|Bacteria,1VD44@1239|Firmicutes,24NC3@186801|Clostridia,3WP9P@541000|Ruminococcaceae 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - - k59_334801_4 742740.HMPREF9474_02271 2.73e-157 458.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia,221RR@1506553|Lachnoclostridium 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_6673_3 1121382.JQKG01000014_gene338 1.43e-07 56.6 COG0210@1|root,COG0210@2|Bacteria,1WN9U@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L UvrD-like helicase C-terminal domain - - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k59_273845_1 1210884.HG799462_gene8275 5.29e-32 129.0 COG0616@1|root,COG0740@1|root,COG0616@2|Bacteria,COG0740@2|Bacteria,2J4WQ@203682|Planctomycetes 203682|Planctomycetes OU serine-type endopeptidase activity - - - - - - - - - - - - - k59_370674_1 1210884.HG799473_gene14924 2.03e-07 58.2 2F5XX@1|root,33YGJ@2|Bacteria,2J3CR@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_334802_1 4577.GRMZM2G131281_P01 5.29e-07 51.6 28PHQ@1|root,2RZR5@2759|Eukaryota,37UKT@33090|Viridiplantae,3GUMW@35493|Streptophyta,3M9X5@4447|Liliopsida,3IR22@38820|Poales 35493|Streptophyta K DNA-binding domain in plant proteins such as APETALA2 and EREBPs - - - - - - - - - - - - AP2 k59_164666_1 1226322.HMPREF1545_00011 5.33e-18 89.0 COG1357@1|root,COG1357@2|Bacteria,1V3RU@1239|Firmicutes,24SV6@186801|Clostridia 186801|Clostridia T Pentapeptide repeats (8 copies) - - - - - - - - - - - - Pentapeptide k59_164666_5 1121456.ATVA01000015_gene2512 4.02e-09 63.2 2C9JF@1|root,32RPD@2|Bacteria,1N8CG@1224|Proteobacteria,42REW@68525|delta/epsilon subdivisions,2WNQ1@28221|Deltaproteobacteria,2MB30@213115|Desulfovibrionales 28221|Deltaproteobacteria S ERF superfamily - - - - - - - - - - - - ERF k59_164666_10 1109445.AGSX01000062_gene761 5.61e-25 110.0 2DPGA@1|root,331YB@2|Bacteria,1N7RM@1224|Proteobacteria,1SB3C@1236|Gammaproteobacteria,1Z45M@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_164666_13 1120977.JHUX01000003_gene776 1.48e-09 60.8 2EMSQ@1|root,33FF4@2|Bacteria,1NDKJ@1224|Proteobacteria,1SDC7@1236|Gammaproteobacteria,3NNBI@468|Moraxellaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1064) - - - - - - - - - - - - DUF1064 k59_200977_1 172088.AUGA01000033_gene4627 1.81e-34 123.0 2FEUE@1|root,346TC@2|Bacteria,1MZPB@1224|Proteobacteria,2UC4Q@28211|Alphaproteobacteria,3K04T@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_18532_1 338969.Rfer_1354 3.54e-26 107.0 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2VHG5@28216|Betaproteobacteria,4ACE0@80864|Comamonadaceae 28216|Betaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase k59_383702_1 935261.JAGL01000009_gene1171 7.25e-45 159.0 COG0258@1|root,COG0258@2|Bacteria,1MYSI@1224|Proteobacteria,2U60N@28211|Alphaproteobacteria 28211|Alphaproteobacteria L 5'-3' exonuclease, N-terminal resolvase-like domain - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc_N k59_202023_1 1122176.KB903609_gene5108 6.08e-17 91.3 COG3210@1|root,COG3210@2|Bacteria 2|Bacteria U domain, Protein - - - - - - - - - - - - CHU_C,DUF4347,He_PIG,PATR,SLH k59_311554_1 1449068.JMLQ01000010_gene3912 0.000887 52.0 29WEI@1|root,30I09@2|Bacteria,2GZAU@201174|Actinobacteria,4FY4R@85025|Nocardiaceae 201174|Actinobacteria S Pectate lyase superfamily protein - - - - - - - - - - - - Pectate_lyase_3 k59_336029_1 648996.Theam_0246 6.95e-21 96.7 COG1185@1|root,COG1185@2|Bacteria,2G3IH@200783|Aquificae 200783|Aquificae J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp - 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 k59_383745_1 1379725.S5TMY9_9CIRC 2.74e-47 165.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_129475_2 1379724.S5T6B0_9CIRC 5.29e-51 176.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_32294_1 469660.A8HP60_9CAUD 9.72e-20 90.1 4QFEN@10239|Viruses,4QYS2@35237|dsDNA viruses no RNA stage,4QSSU@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_226964_5 145579.REP_BPPHM 9e-97 295.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_226964_6 145579.CAPSD_BPPHM 1.31e-224 637.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_226964_7 145579.H_BPPHM 1.44e-21 92.0 4QCA6@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_299821_6 146269.A8YQM5_9CAUD 7e-14 71.2 4QB0C@10239|Viruses,4QW7S@35237|dsDNA viruses no RNA stage,4QPK3@28883|Caudovirales,4QKQC@10699|Siphoviridae 10699|Siphoviridae S magnesium ion binding - - - - - - - - - - - - - k59_299821_7 1343740.M271_31300 0.000184 46.2 COG1396@1|root,COG1396@2|Bacteria,2GP3T@201174|Actinobacteria 201174|Actinobacteria K Helix-turn-helix domain protein - - - - - - - - - - - - HTH_3,HTH_31 k59_166455_1 1211814.CAPG01000027_gene1326 5.21e-10 63.9 COG5301@1|root,COG5301@2|Bacteria,1VEZ9@1239|Firmicutes,4HNUH@91061|Bacilli 91061|Bacilli G cellulose 1,4-beta-cellobiosidase activity - - - - - - - - - - - - - k59_227876_1 1609634.A0A0C5AFT2_9VIRU 4.65e-69 220.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_384683_1 1283300.ATXB01000002_gene2529 3.8e-07 50.1 COG5471@1|root,COG5471@2|Bacteria,1NMSP@1224|Proteobacteria,1SHMP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterized conserved protein (DUF2190) - - - - - - - - - - - - DUF2190 k59_300869_2 340177.Cag_0223 1.76e-07 51.6 COG0629@1|root,COG0629@2|Bacteria,1FE0M@1090|Chlorobi 1090|Chlorobi L PFAM single-strand binding protein Primosomal replication protein n - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_349067_1 1505227.A0A076GAF9_9CAUD 1.46e-23 92.4 4QGQX@10239|Viruses,4QQ2D@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_384686_1 883156.HMPREF9282_00941 5.88e-62 206.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H2W4@909932|Negativicutes 909932|Negativicutes L SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_275836_1 1325372.N0DUB8_9CAUD 6.72e-25 99.8 4QEGD@10239|Viruses,4QVU1@35237|dsDNA viruses no RNA stage,4QPN9@28883|Caudovirales,4QJCM@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_117525_2 1316739.R4JE08_9CAUD 2.35e-05 51.6 4QFSQ@10239|Viruses,4R063@35237|dsDNA viruses no RNA stage,4QT6M@28883|Caudovirales,4QP2G@10744|Podoviridae 10744|Podoviridae S ligase activity - - - - - - - - - - - - - k59_239174_3 1234888.K0A2J2_9VIRU 9.1e-147 435.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_325070_1 665959.HMPREF1013_04817 6.73e-06 54.7 COG0553@1|root,COG0553@2|Bacteria,1UZQK@1239|Firmicutes,4HGNM@91061|Bacilli,1ZD0C@1386|Bacillus 91061|Bacilli KL Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair - - - - - - - - - - - - Helicase_C k59_19468_2 1121422.AUMW01000021_gene1621 6.79e-23 95.9 COG3108@1|root,COG3409@1|root,COG3108@2|Bacteria,COG3409@2|Bacteria 2|Bacteria M Peptidoglycan-binding domain 1 protein - - 3.4.17.14 ko:K08640 - - - - ko00000,ko01000,ko01002,ko01011 - - - PG_binding_1,Peptidase_M15_3,Transglycosylas k59_154845_2 864051.BurJ1DRAFT_0564 4.91e-15 71.6 2EBPV@1|root,335PY@2|Bacteria,1NK03@1224|Proteobacteria,2VY2U@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - DUF1360 k59_117671_1 398512.JQKC01000017_gene3068 3.12e-13 71.6 COG3507@1|root,COG4733@1|root,COG3507@2|Bacteria,COG4733@2|Bacteria,1UYQE@1239|Firmicutes,24C16@186801|Clostridia,3WI7H@541000|Ruminococcaceae 186801|Clostridia G Parallel beta-helix repeats - - - - - - - - - - - - CBM_6,Dockerin_1,Laminin_G_3 k59_228048_3 35703.DQ02_13795 1.6e-36 132.0 COG3926@1|root,COG3926@2|Bacteria,1QV3R@1224|Proteobacteria,1T276@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Glycosyl hydrolase 108 - - - - - - - - - - - - CHAP k59_81769_2 349741.Amuc_1497 4.73e-15 77.4 2BDDY@1|root,32730@2|Bacteria,46WKY@74201|Verrucomicrobia,2IWBU@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - k59_69789_1 1618254.A0A0C5IBG4_9CIRC 6.36e-59 190.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_142519_1 1123250.KB908410_gene1949 1.63e-07 58.2 COG0749@1|root,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H1ZM@909932|Negativicutes 909932|Negativicutes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - - - - - - - - - - - DNA_pol_A,DNA_pol_A_exo1 k59_349260_1 11082.PRO_0000037753 3.54e-115 360.0 4QBXT@10239|Viruses,4R138@439488|ssRNA viruses,4R0R1@35278|ssRNA positive-strand viruses no DNA stage 10239|Viruses K ATP-dependent helicase activity - GO:0000122,GO:0001172,GO:0001510,GO:0001558,GO:0001817,GO:0001818,GO:0001932,GO:0001933,GO:0001934,GO:0001959,GO:0001960,GO:0001961,GO:0002039,GO:0002673,GO:0002674,GO:0002682,GO:0002683,GO:0002694,GO:0002695,GO:0002697,GO:0002698,GO:0002791,GO:0002792,GO:0002831,GO:0002832,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003725,GO:0003727,GO:0003824,GO:0003968,GO:0004175,GO:0004252,GO:0004483,GO:0005102,GO:0005124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005793,GO:0006139,GO:0006355,GO:0006357,GO:0006396,GO:0006417,GO:0006508,GO:0006725,GO:0006807,GO:0006810,GO:0006897,GO:0006898,GO:0007155,GO:0007159,GO:0008104,GO:0008134,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008174,GO:0008233,GO:0008236,GO:0008270,GO:0008284,GO:0008285,GO:0008757,GO:0009058,GO:0009059,GO:0009451,GO:0009452,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010562,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010639,GO:0010646,GO:0010647,GO:0010648,GO:0010692,GO:0010694,GO:0010803,GO:0010804,GO:0010821,GO:0010823,GO:0010921,GO:0010922,GO:0010941,GO:0015031,GO:0015833,GO:0016020,GO:0016032,GO:0016070,GO:0016071,GO:0016192,GO:0016462,GO:0016556,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017016,GO:0017111,GO:0017137,GO:0017151,GO:0017171,GO:0018130,GO:0018995,GO:0019048,GO:0019049,GO:0019050,GO:0019054,GO:0019056,GO:0019058,GO:0019065,GO:0019068,GO:0019080,GO:0019082,GO:0019215,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019899,GO:0019900,GO:0019902,GO:0019903,GO:0020012,GO:0022610,GO:0023051,GO:0023056,GO:0023057,GO:0030162,GO:0030234,GO:0030260,GO:0030307,GO:0030430,GO:0030682,GO:0030683,GO:0030888,GO:0030889,GO:0031072,GO:0031090,GO:0031267,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031329,GO:0031330,GO:0031347,GO:0031348,GO:0031369,GO:0031399,GO:0031400,GO:0031401,GO:0031952,GO:0031953,GO:0032069,GO:0032074,GO:0032101,GO:0032102,GO:0032259,GO:0032268,GO:0032269,GO:0032270,GO:0032386,GO:0032465,GO:0032467,GO:0032675,GO:0032715,GO:0032774,GO:0032780,GO:0032879,GO:0032880,GO:0032944,GO:0032945,GO:0032991,GO:0032993,GO:0033036,GO:0033043,GO:0033116,GO:0033592,GO:0033643,GO:0033644,GO:0033645,GO:0033646,GO:0033647,GO:0033648,GO:0033650,GO:0033655,GO:0033662,GO:0033663,GO:0033668,GO:0033673,GO:0034062,GO:0034121,GO:0034122,GO:0034135,GO:0034136,GO:0034143,GO:0034144,GO:0034155,GO:0034156,GO:0034163,GO:0034164,GO:0034248,GO:0034250,GO:0034641,GO:0034654,GO:0035303,GO:0035306,GO:0035325,GO:0035663,GO:0035821,GO:0036260,GO:0036265,GO:0039502,GO:0039503,GO:0039506,GO:0039507,GO:0039513,GO:0039516,GO:0039526,GO:0039527,GO:0039547,GO:0039560,GO:0039580,GO:0039584,GO:0039612,GO:0039613,GO:0039644,GO:0039653,GO:0039656,GO:0039657,GO:0039713,GO:0039714,GO:0040008,GO:0042000,GO:0042025,GO:0042127,GO:0042287,GO:0042288,GO:0042325,GO:0042326,GO:0042327,GO:0042509,GO:0042532,GO:0042802,GO:0042886,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043085,GO:0043086,GO:0043122,GO:0043123,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043414,GO:0043462,GO:0043487,GO:0043489,GO:0043549,GO:0043656,GO:0043657,GO:0043900,GO:0043901,GO:0043902,GO:0043903,GO:0044003,GO:0044053,GO:0044068,GO:0044092,GO:0044093,GO:0044164,GO:0044165,GO:0044167,GO:0044177,GO:0044186,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044220,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044279,GO:0044359,GO:0044362,GO:0044403,GO:0044409,GO:0044413,GO:0044414,GO:0044415,GO:0044417,GO:0044419,GO:0044422,GO:0044424,GO:0044444,GO:0044464,GO:0044501,GO:0044531,GO:0044532,GO:0044766,GO:0044833,GO:0044877,GO:0045069,GO:0045070,GO:0045088,GO:0045184,GO:0045727,GO:0045787,GO:0045824,GO:0045862,GO:0045892,GO:0045927,GO:0045934,GO:0045936,GO:0045937,GO:0046425,GO:0046426,GO:0046483,GO:0046718,GO:0046755,GO:0046762,GO:0046774,GO:0046794,GO:0046872,GO:0046914,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048524,GO:0048583,GO:0048584,GO:0048585,GO:0050670,GO:0050672,GO:0050687,GO:0050688,GO:0050689,GO:0050690,GO:0050691,GO:0050708,GO:0050709,GO:0050727,GO:0050728,GO:0050730,GO:0050732,GO:0050776,GO:0050777,GO:0050789,GO:0050790,GO:0050792,GO:0050794,GO:0050864,GO:0050865,GO:0050866,GO:0050869,GO:0050896,GO:0051020,GO:0051046,GO:0051047,GO:0051048,GO:0051049,GO:0051050,GO:0051051,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051223,GO:0051224,GO:0051234,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051249,GO:0051250,GO:0051252,GO:0051253,GO:0051302,GO:0051336,GO:0051338,GO:0051345,GO:0051346,GO:0051348,GO:0051701,GO:0051704,GO:0051707,GO:0051726,GO:0051781,GO:0051805,GO:0051806,GO:0051807,GO:0051808,GO:0051817,GO:0051828,GO:0051832,GO:0051833,GO:0051834,GO:0051836,GO:0052026,GO:0052027,GO:0052029,GO:0052031,GO:0052037,GO:0052038,GO:0052040,GO:0052041,GO:0052053,GO:0052055,GO:0052056,GO:0052148,GO:0052150,GO:0052167,GO:0052170,GO:0052173,GO:0052199,GO:0052200,GO:0052203,GO:0052204,GO:0052205,GO:0052230,GO:0052248,GO:0052250,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052312,GO:0052433,GO:0052490,GO:0052493,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0060147,GO:0060149,GO:0060255,GO:0060338,GO:0060339,GO:0060341,GO:0060548,GO:0060589,GO:0060590,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0060759,GO:0060760,GO:0060761,GO:0060966,GO:0060967,GO:0060968,GO:0060969,GO:0065007,GO:0065008,GO:0065009,GO:0070011,GO:0070103,GO:0070104,GO:0070201,GO:0070486,GO:0070663,GO:0070664,GO:0071593,GO:0071702,GO:0071704,GO:0071705,GO:0072583,GO:0075109,GO:0075111,GO:0075112,GO:0075114,GO:0075136,GO:0075344,GO:0075509,GO:0075512,GO:0075528,GO:0080009,GO:0080090,GO:0080134,GO:0080135,GO:0090068,GO:0090087,GO:0090199,GO:0090201,GO:0090304,GO:0097159,GO:0097617,GO:0097659,GO:0097677,GO:0097747,GO:0098588,GO:0098609,GO:0098657,GO:0098772,GO:0106005,GO:0140096,GO:0140098,GO:1900101,GO:1900102,GO:1900117,GO:1900118,GO:1900368,GO:1900369,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901576,GO:1902369,GO:1902531,GO:1902532,GO:1902533,GO:1902579,GO:1902679,GO:1903265,GO:1903506,GO:1903507,GO:1903530,GO:1903531,GO:1903573,GO:1903719,GO:1903721,GO:1903900,GO:1903902,GO:1904892,GO:1904893,GO:1904950,GO:1905897,GO:1990214,GO:1990216,GO:1990219,GO:1990254,GO:1990814,GO:1990904,GO:2000112,GO:2000113,GO:2001141,GO:2001233,GO:2001234 - - - - - - - - - - - k59_290729_20 1480731.X2KUH8_9CAUD 1.26e-08 67.4 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0008150,GO:0016032,GO:0016787,GO:0016798,GO:0019012,GO:0019058,GO:0019062,GO:0022610,GO:0044403,GO:0044406,GO:0044409,GO:0044411,GO:0044419,GO:0044423,GO:0044650,GO:0051701,GO:0051704,GO:0051828,GO:0051830,GO:0085027,GO:0098015,GO:0098024 - - - - - - - - - - - k59_290729_24 1123508.JH636451_gene5927 8.69e-07 55.1 2DXPM@1|root,345W1@2|Bacteria,2J3SF@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_290729_30 953739.SVEN_2129 8.56e-30 112.0 2BM0Q@1|root,32FHM@2|Bacteria,2IK53@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_290734_1 1444306.JFZC01000040_gene433 1.47e-13 75.5 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,26NDD@186821|Sporolactobacillaceae 91061|Bacilli L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A k59_385683_1 1089548.KI783301_gene2629 2.31e-112 338.0 COG0863@1|root,COG0863@2|Bacteria,1UZIN@1239|Firmicutes,4HU16@91061|Bacilli 91061|Bacilli L DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_385683_4 1121472.AQWN01000009_gene386 1.99e-27 111.0 COG3935@1|root,COG3935@2|Bacteria,1W6YR@1239|Firmicutes,25IDM@186801|Clostridia,266M1@186807|Peptococcaceae 186801|Clostridia L DnaD domain protein - - - - - - - - - - - - - k59_240200_1 685782.O99_00451 2.51e-23 95.9 2EE3H@1|root,337Y3@2|Bacteria,1NF3P@1224|Proteobacteria,2UKX4@28211|Alphaproteobacteria,48U9U@772|Bartonellaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_82799_2 883.DvMF_1637 6.49e-13 66.6 2EMVQ@1|root,33FHY@2|Bacteria,1NNSC@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_276839_1 208960.XP_007271899.1 2.49e-10 63.2 COG1793@1|root,2QTYC@2759|Eukaryota,38GKG@33154|Opisthokonta,3P0B0@4751|Fungi,3V0A0@5204|Basidiomycota,22603@155619|Agaricomycetes,3H1D5@355688|Agaricomycetes incertae sedis 4751|Fungi L DNA ligase mRNA capping enzyme - - 6.5.1.1,6.5.1.6,6.5.1.7 ko:K10747 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00381,R00382,R10822,R10823 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_ligase_A_M,DNA_ligase_OB_2,zf-CCHH k59_188850_1 1235661.K0IGL1_9CAUD 6.57e-56 203.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNI0@10744|Podoviridae 10744|Podoviridae S viral capsid - GO:0003674,GO:0005488,GO:0005515,GO:0042802 - - - - - - - - - - - k59_326296_1 1986029.Q9MBM8_9VIRU 3.3e-68 232.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_9552_1 575788.VS_1436 3.18e-06 49.3 2AWQ6@1|root,31NM4@2|Bacteria,1QKBR@1224|Proteobacteria,1TIF6@1236|Gammaproteobacteria,1XZ0V@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k59_156015_1 1458858.A0A088C4S7_9CAUD 2.14e-23 109.0 4QGM3@10239|Viruses,4QYG4@35237|dsDNA viruses no RNA stage,4QPTC@28883|Caudovirales,4QKCW@10662|Myoviridae 10662|Myoviridae S oxidoreductase activity - - - - - - - - - - - - - k59_20660_1 1217658.F987_03916 3.2e-08 59.7 COG1442@1|root,COG1442@2|Bacteria,1NJ1J@1224|Proteobacteria,1S14E@1236|Gammaproteobacteria,3NJRC@468|Moraxellaceae 1236|Gammaproteobacteria M glycosyl transferase family 8 - - - - - - - - - - - - Glyco_transf_8 k59_70755_2 1234888.K0A2J2_9VIRU 8.9e-108 337.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_131819_1 1120963.KB894511_gene2539 6.02e-13 69.3 COG3772@1|root,COG3772@2|Bacteria,1N0ZQ@1224|Proteobacteria,1S9AE@1236|Gammaproteobacteria,2Q38I@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_241452_1 1333523.L593_09880 0.000943 43.5 COG1199@1|root,arCOG00770@2157|Archaea,2XSWZ@28890|Euryarchaeota,23S1B@183963|Halobacteria 183963|Halobacteria K COG1199 Rad3-related DNA helicases - - - - - - - - - - - - DEAD_2,Helicase_C_2 k59_314786_1 2003327.CAPSD_BPCHP 3.6e-60 204.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_97064_1 1609634.A0A0C5AFV4_9VIRU 6.98e-66 218.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_386874_1 742733.HMPREF9469_05023 2.22e-38 136.0 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia,222RY@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_35609_1 323097.Nham_3328 7.14e-14 77.0 COG5301@1|root,COG5301@2|Bacteria,1N6XX@1224|Proteobacteria,2USJX@28211|Alphaproteobacteria 28211|Alphaproteobacteria G cellulose 1,4-beta-cellobiosidase activity - - - - - - - - - - - - - k59_303222_1 268748.Q58N42_BPPRP 2.53e-18 89.4 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_181562_1 644107.SL1157_0762 1.22e-38 144.0 COG3598@1|root,COG3598@2|Bacteria,1PGIX@1224|Proteobacteria,2V1SC@28211|Alphaproteobacteria,4NDPA@97050|Ruegeria 28211|Alphaproteobacteria L AAA domain - - - - - - - - - - - - AAA_25 k59_339442_2 1300350.DSW25_10755 4.75e-22 96.3 COG3914@1|root,COG3914@2|Bacteria,1RC2I@1224|Proteobacteria,2U5BE@28211|Alphaproteobacteria,3ZVJF@60136|Sulfitobacter 28211|Alphaproteobacteria O O-linked N-acetylglucosamine transferase SPINDLY family - - - - - - - - - - - - - k59_21711_3 46681.XP_001738227.1 4.52e-38 144.0 2CSEE@1|root,2RBK2@2759|Eukaryota,3X9MH@554915|Amoebozoa 554915|Amoebozoa G RNA helicase - - - - - - - - - - - - RNA_helicase k59_119712_1 145579.CAPSD_BPPHM 3.75e-34 135.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_278113_1 1265507.KB899636_gene1626 1.13e-12 72.0 COG2887@1|root,COG2887@2|Bacteria,1QEBA@1224|Proteobacteria,1RSK2@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_133045_3 2045.KR76_11020 2.55e-12 72.0 COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria,4DQU1@85009|Propionibacteriales 201174|Actinobacteria M NlpC/P60 family - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60 k59_255203_33 1479623.JHEL01000015_gene806 3.43e-72 249.0 COG1061@1|root,COG1061@2|Bacteria,2GIU5@201174|Actinobacteria,4FM8J@85023|Microbacteriaceae 201174|Actinobacteria L Type III restriction enzyme, res subunit sdrA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - ResIII k59_255203_38 1274402.JQAJ01000003_gene756 7.13e-09 60.5 2DPV5@1|root,333HH@2|Bacteria,1NCA9@1224|Proteobacteria,2UHMY@28211|Alphaproteobacteria,47FF4@766|Rickettsiales 766|Rickettsiales - - - - - - - - - - - - - - - k59_255203_41 323261.Noc_3023 5.26e-42 144.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,1WY0C@135613|Chromatiales 135613|Chromatiales L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_255203_47 1123072.AUDH01000035_gene1395 4.54e-47 161.0 28NSJ@1|root,2ZBRH@2|Bacteria,1RAXM@1224|Proteobacteria,2U60W@28211|Alphaproteobacteria,2JU5F@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_255203_48 658401.C7F4B8_9CAUD 4.65e-05 55.5 4QH5W@10239|Viruses,4QYFG@35237|dsDNA viruses no RNA stage,4QQD8@28883|Caudovirales,4QN2T@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_97318_2 1123034.JMKP01000004_gene1749 1.9e-17 92.4 28MJ5@1|root,2ZAVR@2|Bacteria,1R5CR@1224|Proteobacteria,1SCPR@1236|Gammaproteobacteria,3NMDZ@468|Moraxellaceae 1236|Gammaproteobacteria S Phage stabilisation protein - - - - - - - - - - - - Phage_stabilise k59_121696_1 1096930.L284_17065 2.21e-53 200.0 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,2TVEI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA polymerase family A - - - - - - - - - - - - DNA_pol_A k59_267371_1 342113.DM82_4335 9.78e-66 228.0 COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria 1224|Proteobacteria K DNA-dependent RNA polymerase - - 2.7.7.6 ko:K21313 - - - - ko00000,ko01000,ko03200 - - - RNA_pol,RPOL_N k59_291770_1 360094.PXO_00919 7.88e-05 45.4 COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,1S60Z@1236|Gammaproteobacteria,1X61I@135614|Xanthomonadales 135614|Xanthomonadales FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA - - - - - - - - - - - Acetyltransf_1,MafB19-deam,dCMP_cyt_deam_1 k59_218953_1 186617.M9M8L2_9VIRU 6.01e-43 153.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_218953_3 1165094.RINTHH_3920 2.07e-47 167.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_328251_1 68570.DC74_2981 8.57e-08 61.6 COG1475@1|root,COG1475@2|Bacteria,2IF26@201174|Actinobacteria 201174|Actinobacteria K ParB-like nuclease domain - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_376876_1 1548905.A0A0A1IX16_9CAUD 4.72e-41 145.0 4QBTT@10239|Viruses,4QQUU@28883|Caudovirales,4QKWB@10699|Siphoviridae 10699|Siphoviridae S Phage conserved hypothetical protein BR0599 - - - - - - - - - - - - - k59_60939_1 243159.AFE_1260 1.65e-17 80.9 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,2NCW5@225057|Acidithiobacillales 225057|Acidithiobacillales L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_60939_2 1125863.JAFN01000001_gene3542 3.37e-23 94.7 COG2852@1|root,COG2852@2|Bacteria,1N2UX@1224|Proteobacteria 1224|Proteobacteria S Protein conserved in bacteria - - - - - - - - - - - - - k59_109507_2 518766.Rmar_2392 1.58e-13 82.4 COG3866@1|root,COG3866@2|Bacteria,4P09P@976|Bacteroidetes 976|Bacteroidetes G Pectate lyase - - - - - - - - - - - - - k59_267402_1 1609634.A0A0C5AFV4_9VIRU 7.38e-90 285.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_267402_3 1385658.U5KNR1_9VIRU 5.13e-79 249.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_25890_4 1283340.Q6WI94_BPKVM 6.03e-52 189.0 4QAUT@10239|Viruses,4QVIM@35237|dsDNA viruses no RNA stage,4QQ7X@28883|Caudovirales,4QIGV@10662|Myoviridae 10662|Myoviridae S DNA ligase (ATP) activity - - - - - - - - - - - - - k59_25890_13 1564096.A0A0A0YT02_9CAUD 2.08e-25 105.0 4QC6N@10239|Viruses,4QPEG@28883|Caudovirales,4QI30@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_354219_2 77856.REP_BFDV 6.92e-29 119.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_147497_5 698757.Pogu_0468 5.53e-08 60.5 COG0209@1|root,COG1372@1|root,arCOG03151@2157|Archaea,arCOG04276@2157|Archaea,2XQ2F@28889|Crenarchaeota 28889|Crenarchaeota F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrd - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Intein_splicing,LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN k59_354222_1 1100720.ALKN01000018_gene1738 2.85e-44 162.0 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,2VQF3@28216|Betaproteobacteria,4ADUP@80864|Comamonadaceae 28216|Betaproteobacteria L Helicase conserved C-terminal domain - - - - - - - - - - - - Helicase_C,ResIII,UPF0547 k59_183387_1 28152.DJ57_2429 9.07e-22 86.7 COG0695@1|root,COG0695@2|Bacteria,1N7YD@1224|Proteobacteria,1SCFR@1236|Gammaproteobacteria,41GGM@629|Yersinia 1236|Gammaproteobacteria O glrX_NrdH glutaredoxin-like NrdH family protein nrdH GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009893,GO:0009987,GO:0016491,GO:0019222,GO:0019725,GO:0022900,GO:0042592,GO:0043085,GO:0044093,GO:0044237,GO:0045454,GO:0048518,GO:0050789,GO:0050790,GO:0050794,GO:0051341,GO:0051353,GO:0055114,GO:0065007,GO:0065008,GO:0065009 - ko:K06191 - - - - ko00000 - - - Glutaredoxin k59_171806_2 398578.Daci_1924 2.74e-21 88.2 2CDJG@1|root,2ZWR7@2|Bacteria,1P7YQ@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_123402_1 1380394.JADL01000006_gene5266 4.64e-53 182.0 COG1783@1|root,COG1783@2|Bacteria,1MVJB@1224|Proteobacteria,2U2BM@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_159801_1 93220.LV28_24555 3.2e-71 226.0 COG0338@1|root,COG0338@2|Bacteria,1P85S@1224|Proteobacteria,2VNFF@28216|Betaproteobacteria,1K7JE@119060|Burkholderiaceae 28216|Betaproteobacteria L D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_38066_1 1609634.A0A0C5AFV4_9VIRU 4.71e-49 174.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_98891_2 428125.CLOLEP_01398 3.63e-29 107.0 2CGGB@1|root,32UNH@2|Bacteria,1VD9W@1239|Firmicutes,24MWC@186801|Clostridia,3WPKG@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_196143_2 1609634.A0A0C5AFV4_9VIRU 1.24e-23 100.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_232516_2 1618259.A0A0C5I2B5_9CIRC 1.41e-75 239.0 4QE84@10239|Viruses,4QUKR@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_147507_1 1234888.K0A2J2_9VIRU 1.18e-124 375.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_293529_1 145579.CAPSD_BPPHM 7.81e-64 218.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_208548_2 291607.REP6_SCSVF 8.48e-15 76.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_318790_1 1692244.A0A0K1RLR5_9CIRC 1.65e-65 211.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_26769_1 557598.LHK_01539 5.76e-75 244.0 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,2VU8A@28216|Betaproteobacteria 28216|Betaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_282817_1 319003.Bra1253DRAFT_08459 9.97e-06 58.2 2F5DG@1|root,33XZC@2|Bacteria,1RKCR@1224|Proteobacteria,2UBMH@28211|Alphaproteobacteria,3K2MH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_197015_1 1692249.A0A0K1RL40_9CIRC 2.32e-45 159.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_306359_1 1408428.JNJP01000005_gene5 5.22e-09 59.7 2C9JF@1|root,32RPD@2|Bacteria,1N8CG@1224|Proteobacteria,42REW@68525|delta/epsilon subdivisions,2WNQ1@28221|Deltaproteobacteria,2MB30@213115|Desulfovibrionales 28221|Deltaproteobacteria S ERF superfamily - - - - - - - - - - - - ERF k59_63540_6 1288484.APCS01000031_gene2346 5.62e-99 316.0 COG5362@1|root,COG5362@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Terminase_6C k59_51095_1 1788444.A0A190WHB9_9CIRC 9.13e-48 168.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_245273_3 1120934.KB894459_gene1386 1.19e-12 70.9 2E1TZ@1|root,32X3N@2|Bacteria,2IH16@201174|Actinobacteria,4EBC0@85010|Pseudonocardiales 201174|Actinobacteria S AAA domain - - - - - - - - - - - - AAA_25 k59_26775_1 631362.Thi970DRAFT_01900 1.93e-07 56.2 COG0582@1|root,COG0582@2|Bacteria,1MWBN@1224|Proteobacteria,1RPD0@1236|Gammaproteobacteria,1WYV7@135613|Chromatiales 135613|Chromatiales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k59_75362_1 1123508.JH636448_gene7701 1.5e-25 107.0 COG4422@1|root,COG4422@2|Bacteria 2|Bacteria F Protein of unknown function (DUF5131) - - - - - - - - - - - - DUF5131 k59_99654_2 1158150.KB906242_gene214 7.78e-77 241.0 COG0258@1|root,COG0258@2|Bacteria,1MYSI@1224|Proteobacteria,1SQ55@1236|Gammaproteobacteria 1236|Gammaproteobacteria L 5'-3' exonuclease, N-terminal resolvase-like domain - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc_N k59_318796_1 1279009.ADICEAN_03579 1.33e-45 165.0 COG1690@1|root,COG1690@2|Bacteria,4NG8T@976|Bacteroidetes,47N9X@768503|Cytophagia 976|Bacteroidetes S tRNA-splicing ligase RtcB - - 6.5.1.3 ko:K14415 - - - - ko00000,ko01000,ko03016 - - - RtcB k59_51098_2 665571.STHERM_c17410 2e-15 75.1 COG4696@1|root,COG4696@2|Bacteria 2|Bacteria J Protein conserved in bacteria XK27_03185 - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - Acetyltransf_3,Hydrolase_3,PRA-PH k59_63543_2 1236573.K4LRR0_9CAUD 4.62e-08 58.9 4QBFR@10239|Viruses,4QV1E@35237|dsDNA viruses no RNA stage,4QPRX@28883|Caudovirales,4QKMP@10699|Siphoviridae 10699|Siphoviridae S ERF superfamily - - - - - - - - - - - - - k59_51230_1 598467.BrE312_2697 7.62e-31 133.0 28HCK@1|root,2Z7PE@2|Bacteria,1NK7S@1224|Proteobacteria,1S03Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_63717_1 1121935.AQXX01000130_gene2425 9.37e-41 139.0 2AD08@1|root,312N7@2|Bacteria,1NDC4@1224|Proteobacteria,1SAPT@1236|Gammaproteobacteria,1XQHK@135619|Oceanospirillales 135619|Oceanospirillales S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_111897_1 1123487.KB892865_gene1388 2.86e-30 127.0 COG3378@1|root,COG3378@2|Bacteria 2|Bacteria KL Phage plasmid primase P4 family - - - ko:K06919 - - - - ko00000 - - - PriCT_2,Prim-Pol k59_51976_3 1235803.C825_01399 6.19e-10 62.0 COG2852@1|root,COG2852@2|Bacteria,4NX7B@976|Bacteroidetes,2FV38@200643|Bacteroidia 976|Bacteroidetes S Protein conserved in bacteria - - - - - - - - - - - - - k59_51976_4 1150621.SMUL_1787 4.12e-43 157.0 COG0338@1|root,COG0338@2|Bacteria,1P85S@1224|Proteobacteria,42RAF@68525|delta/epsilon subdivisions,2YP2J@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria H Site-specific DNA-methyltransferase (Adenine-specific) - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_210344_1 428125.CLOLEP_01400 1.78e-136 422.0 28JED@1|root,2Z98K@2|Bacteria,1TW1U@1239|Firmicutes,24CFD@186801|Clostridia,3WNW0@541000|Ruminococcaceae 186801|Clostridia K Bacterial regulatory proteins, luxR family - - - - - - - - - - - - GerE k59_76208_3 187303.BN69_1626 1.12e-09 68.2 COG1475@1|root,COG4725@1|root,COG1475@2|Bacteria,COG4725@2|Bacteria,1R553@1224|Proteobacteria,2TRP6@28211|Alphaproteobacteria,36XZ4@31993|Methylocystaceae 28211|Alphaproteobacteria KT MT-A70 - - - - - - - - - - - - MT-A70,ParBc k59_246180_5 198467.NP92_00275 4.91e-24 102.0 COG1388@1|root,COG3023@1|root,COG3409@1|root,COG1388@2|Bacteria,COG3023@2|Bacteria,COG3409@2|Bacteria,1V5SV@1239|Firmicutes,4HI8B@91061|Bacilli,21WNR@150247|Anoxybacillus 91061|Bacilli MV Ami_2 - - - - - - - - - - - - Amidase_2,Cu_amine_oxidN1,LysM,PG_binding_1 k59_258594_4 1334046.AYTB01000013_gene436 9.86e-12 68.6 COG0582@1|root,COG0582@2|Bacteria,1V2RX@1239|Firmicutes,4HJ45@91061|Bacilli,26IDK@186818|Planococcaceae 91061|Bacilli L Phage integrase family - - - - - - - - - - - - Phage_integrase k59_258594_5 1190606.AJYG01000064_gene1361 1.32e-13 68.6 2AD08@1|root,312N7@2|Bacteria,1NDC4@1224|Proteobacteria,1SAPT@1236|Gammaproteobacteria,1Y0U2@135623|Vibrionales 135623|Vibrionales S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_234395_2 1788444.A0A190WHA5_9CIRC 2.93e-14 82.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_100890_2 574966.KB898655_gene1599 1.15e-61 205.0 COG4128@1|root,COG4128@2|Bacteria,1REHG@1224|Proteobacteria,1S491@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_246367_1 1385658.U5KPZ6_9VIRU 3.1e-152 447.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_64584_2 1609634.A0A0C5AFV4_9VIRU 9.79e-32 129.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_381036_1 525257.HMPREF0204_11349 5.99e-18 90.1 COG1511@1|root,COG3941@1|root,COG1511@2|Bacteria,COG3941@2|Bacteria,4PNE3@976|Bacteroidetes,1IK3W@117743|Flavobacteriia 976|Bacteroidetes S tape measure - - - - - - - - - - - - - k59_52988_1 96561.Dole_2911 4.05e-11 71.2 COG3378@1|root,COG3378@2|Bacteria,1QUII@1224|Proteobacteria,43AF6@68525|delta/epsilon subdivisions,2X5UX@28221|Deltaproteobacteria 28221|Deltaproteobacteria L Poxvirus D5 protein-like - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5 k59_4555_1 441620.Mpop_0007 4.81e-06 52.0 28JWE@1|root,2Z9M6@2|Bacteria,1R76R@1224|Proteobacteria,2U0BP@28211|Alphaproteobacteria,1JU2G@119045|Methylobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_150120_7 1210884.HG799462_gene9061 2.37e-19 84.0 2EH0T@1|root,33ASV@2|Bacteria 2|Bacteria S VRR-NUC domain - - - - - - - - - - - - VRR_NUC k59_150120_9 1121468.AUBR01000081_gene831 6.17e-49 181.0 COG0863@1|root,COG0863@2|Bacteria,1TR56@1239|Firmicutes,248NR@186801|Clostridia 186801|Clostridia L Belongs to the N(4) N(6)-methyltransferase family cfr9IM - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_150120_10 1070319.CAGGBEG34_210101 2.7e-14 74.7 COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,2VUKW@28216|Betaproteobacteria,1K0ME@119060|Burkholderiaceae 28216|Betaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_332621_4 411684.HPDFL43_12908 2.71e-20 97.1 COG3179@1|root,COG3409@1|root,COG3179@2|Bacteria,COG3409@2|Bacteria,1R71F@1224|Proteobacteria,2VF0B@28211|Alphaproteobacteria,43R6I@69277|Phyllobacteriaceae 28211|Alphaproteobacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - Glyco_hydro_19,Peptidase_M15_4 k59_101807_4 487316.BBNM01000022_gene5 3.9e-31 115.0 COG0791@1|root,COG0791@2|Bacteria,1QP6S@1224|Proteobacteria,1SIU8@1236|Gammaproteobacteria,3NN30@468|Moraxellaceae 1236|Gammaproteobacteria M NlpC/P60 family - - - - - - - - - - - - NLPC_P60 k59_101807_7 1150626.PHAMO_80087 1.87e-16 93.6 COG3941@1|root,COG3941@2|Bacteria,1PHQP@1224|Proteobacteria,2V9RW@28211|Alphaproteobacteria,2JWSI@204441|Rhodospirillales 204441|Rhodospirillales S Lambda phage tail tape-measure protein (Tape_meas_lam_C) - - - - - - - - - - - - Tape_meas_lam_C k59_101807_13 643562.Daes_2400 2.5e-10 62.8 COG4387@1|root,COG4387@2|Bacteria,1N1K0@1224|Proteobacteria,42W85@68525|delta/epsilon subdivisions,2WRV3@28221|Deltaproteobacteria,2MD2H@213115|Desulfovibrionales 28221|Deltaproteobacteria S Protein of unknown function (DUF1320) - - - - - - - - - - - - DUF1320 k59_223546_5 1280944.HY17_04590 1.87e-24 99.4 COG0863@1|root,COG0863@2|Bacteria,1R7RR@1224|Proteobacteria,2TS8Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase k59_271687_1 1385658.U5KNR1_9VIRU 6.2e-50 172.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_150255_1 1458697.W6E8P3_9CAUD 8.69e-08 63.2 4QB9Y@10239|Viruses,4QWGZ@35237|dsDNA viruses no RNA stage,4QPTT@28883|Caudovirales,4QKUM@10699|Siphoviridae 10699|Siphoviridae S hydrolase activity, acting on acid anhydrides - - - - - - - - - - - - - k59_101815_2 1463887.KL589968_gene7436 5.04e-11 60.5 2B303@1|root,31VMA@2|Bacteria,2GVW7@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_77347_2 261292.Nit79A3_2404 7.53e-17 82.4 2AFXG@1|root,31610@2|Bacteria,1PWPJ@1224|Proteobacteria,2VWSI@28216|Betaproteobacteria,374EY@32003|Nitrosomonadales 28216|Betaproteobacteria S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 k59_138049_1 1537917.JU82_09980 1.11e-14 71.6 2ARVA@1|root,31H70@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - HK97-gp10_like k59_138049_2 742740.HMPREF9474_02265 6.7e-61 194.0 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia,222RY@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_235256_1 1385658.U5KPZ6_9VIRU 1.59e-98 306.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_126304_1 1460640.JCM19046_3530 2.3e-38 150.0 COG0863@1|root,COG0863@2|Bacteria,1TR56@1239|Firmicutes,4HHJ7@91061|Bacilli,1ZKIN@1386|Bacillus 91061|Bacilli L DNA methylase - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_53126_2 105154.Q9MBU3_9VIRU 9.77e-12 68.6 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_65514_1 1266845.Q783_03235 9.16e-06 53.5 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,27FQ5@186828|Carnobacteriaceae 91061|Bacilli L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A k59_333830_1 1273707.L7TID4_9CAUD 2.05e-20 100.0 4QBTM@10239|Viruses,4QWCV@35237|dsDNA viruses no RNA stage,4QRTG@28883|Caudovirales,4QNB6@10744|Podoviridae 10744|Podoviridae S Methyltransferase small domain - - - - - - - - - - - - - k59_78521_1 1234888.K0A2J2_9VIRU 5.86e-33 131.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_5849_1 1121935.AQXX01000130_gene2427 2.17e-21 89.7 2DMPB@1|root,32SV8@2|Bacteria,1NHUE@1224|Proteobacteria,1SIKI@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_114628_2 586413.CCDL010000004_gene3495 2.04e-06 57.4 COG3409@1|root,COG3409@2|Bacteria,1VG7I@1239|Firmicutes,4ITUA@91061|Bacilli 91061|Bacilli M Putative peptidoglycan binding domain - - - - - - - - - - - - Glyco_hydro_25,PG_binding_1 k59_151468_1 1618259.A0A0C5I2B5_9CIRC 5.59e-105 312.0 4QE84@10239|Viruses,4QUKR@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_114636_1 469618.FVAG_00948 3.2e-05 50.8 COG1595@1|root,COG1595@2|Bacteria,37AEG@32066|Fusobacteria 32066|Fusobacteria K Psort location Cytoplasmic, score 8.96 - - - ko:K03091 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k59_200033_1 1123502.AQXD01000002_gene173 3.79e-06 53.1 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1X3IJ@135614|Xanthomonadales 135614|Xanthomonadales K Belongs to the ParB family parB - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_78522_2 667014.Thein_0190 1.11e-32 127.0 COG1191@1|root,COG1191@2|Bacteria,2GHGC@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria K Sigma-70, region 4 - - - ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 - - - ko00000,ko00001,ko02035,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k59_163725_1 158190.SpiGrapes_2827 6.38e-43 155.0 COG4695@1|root,COG4695@2|Bacteria,2J583@203691|Spirochaetes 203691|Spirochaetes S Phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_212870_1 1541065.JRFE01000034_gene6108 1.01e-47 168.0 2CC4J@1|root,2Z7W8@2|Bacteria,1G4C9@1117|Cyanobacteria 1117|Cyanobacteria S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_102964_3 948071.S4S2D9_9CAUD 2.87e-92 290.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae 10744|Podoviridae S ribonucleoside-triphosphate reductase activity - - - - - - - - - - - - - k59_200038_1 691965.D4P7E6_9CAUD 1.17e-07 63.9 4QAK6@10239|Viruses,4R01K@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_322784_2 1692242.A0A0K1RKZ2_9CIRC 7.35e-35 132.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_67451_1 1234888.K0A2J2_9VIRU 4.48e-44 159.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_176918_2 330084.JNYZ01000003_gene2277 5.52e-22 93.2 2BM0Q@1|root,32FHM@2|Bacteria,2IK53@201174|Actinobacteria,4ECAS@85010|Pseudonocardiales 201174|Actinobacteria - - - - - - - - - - - - - - - k59_176918_10 1123487.KB892865_gene1372 6.55e-57 187.0 2ECIJ@1|root,336GQ@2|Bacteria,1NFBI@1224|Proteobacteria,2VYFZ@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_176918_13 1123487.KB892865_gene1375 3.88e-194 546.0 28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria,2VPRP@28216|Betaproteobacteria,2KZJK@206389|Rhodocyclales 206389|Rhodocyclales S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_176918_16 1123487.KB892865_gene1380 8.51e-63 219.0 COG3170@1|root,COG3170@2|Bacteria,1PMRK@1224|Proteobacteria,2W7ZG@28216|Betaproteobacteria,2KZB6@206389|Rhodocyclales 206389|Rhodocyclales NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - k59_55060_2 484022.Fphi_1687 1.51e-32 129.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,45ZTN@72273|Thiotrichales 72273|Thiotrichales L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_310450_1 1986029.Q9MBM8_9VIRU 2.91e-31 121.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_310450_2 1609634.A0A0C5ANA6_9VIRU 1.26e-11 66.2 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_92100_1 1609634.A0A0C5ANA6_9VIRU 4.56e-06 48.9 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_237114_1 1037409.BJ6T_75590 6.31e-18 92.0 COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,2TS0U@28211|Alphaproteobacteria,3JRSC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8 k59_152709_1 1121423.JONT01000001_gene2113 3.43e-40 153.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,2605R@186807|Peptococcaceae 186801|Clostridia L DNA polymerase III alpha subunit dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k59_31231_1 400668.Mmwyl1_0577 1.54e-38 135.0 2AFF0@1|root,315F0@2|Bacteria,1RHGE@1224|Proteobacteria,1S6YG@1236|Gammaproteobacteria,1XKMC@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k59_322978_2 1347393.HG726020_gene899 2.03e-11 64.7 COG4695@1|root,COG4695@2|Bacteria 2|Bacteria N Portal protein - - - - - - - - - - - - Phage_portal k59_249630_1 935548.KI912159_gene123 1.93e-12 69.3 COG4653@1|root,COG4653@2|Bacteria 2|Bacteria G Phage capsid family xkdG - - - - - - - - - - - Phage_capsid k59_261312_1 378806.STAUR_4010 0.000497 48.5 COG1215@1|root,COG1215@2|Bacteria,1MXXV@1224|Proteobacteria,43AI5@68525|delta/epsilon subdivisions,2X5YC@28221|Deltaproteobacteria,2YVDH@29|Myxococcales 28221|Deltaproteobacteria M Chitin synthase - - 2.4.1.212 ko:K00752 - - - - ko00000,ko01000,ko01003,ko02000 4.D.1.1.10,4.D.1.1.4,4.D.1.1.5 GT2 - Glycos_transf_2,PilZ k59_97749_3 517722.AEUE01000002_gene2193 1.57e-06 51.6 2DSHN@1|root,33G5Q@2|Bacteria,1NGM3@1224|Proteobacteria,2UK0H@28211|Alphaproteobacteria,2K4KJ@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - k59_219489_1 1082932.ATCR1_06746 4.44e-15 81.6 COG2268@1|root,COG2268@2|Bacteria,1NT13@1224|Proteobacteria,2U335@28211|Alphaproteobacteria,4BCZZ@82115|Rhizobiaceae 28211|Alphaproteobacteria S Band 7 protein - - - - - - - - - - - - - k59_158681_2 1392540.P256_00045 6e-25 96.7 2BRZC@1|root,32KZQ@2|Bacteria,1Q31I@1224|Proteobacteria,1RSVN@1236|Gammaproteobacteria,3NRT9@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_146422_4 1357272.AVEO02000155_gene303 5.43e-11 58.9 COG1551@1|root,COG1551@2|Bacteria,1N6PG@1224|Proteobacteria,1SCB4@1236|Gammaproteobacteria,1Z87F@136849|Pseudomonas syringae group 1236|Gammaproteobacteria J Could accelerate the degradation of some genes transcripts potentially through selective RNA binding rsmE - - ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 - - - ko00000,ko00001,ko03019 - - - CsrA k59_97754_2 395494.Galf_0949 8.32e-06 48.1 COG3723@1|root,COG3723@2|Bacteria,1R6DB@1224|Proteobacteria,2VNV4@28216|Betaproteobacteria 28216|Betaproteobacteria L RecT family recT - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_316548_1 1219035.NT2_13_00580 2.39e-22 100.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_49341_3 882.DVU_0959 2.78e-13 71.2 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2WJCA@28221|Deltaproteobacteria,2M7ZB@213115|Desulfovibrionales 28221|Deltaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_328698_1 1618248.A0A0C5IB82_9CIRC 2.12e-89 275.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_353082_2 1609634.A0A0C5AFT2_9VIRU 3.17e-59 199.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_316552_1 1234888.K0A2J2_9VIRU 1.01e-65 221.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_243457_2 1234888.K0A2R8_9VIRU 3.92e-36 137.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_1558_8 1441930.Z042_23145 4.17e-35 125.0 2D1MV@1|root,32TAZ@2|Bacteria,1N45A@1224|Proteobacteria,1S954@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage protein (N4 Gp49/phage Sf6 gene 66) family - - - - - - - - - - - - DUF2829,Phage_gp49_66 k59_1558_10 1540097.A0A0A0YRN0_9CAUD 8.2e-226 654.0 4QF3C@10239|Viruses,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_281526_1 1340493.JNIF01000003_gene2420 1.43e-12 72.8 2DP40@1|root,330F7@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_208363_1 1123508.JH636442_gene4493 7.38e-35 137.0 28JU3@1|root,2Z9J6@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_341599_4 2003327.CAPSD_BPCHP 1.54e-61 208.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_329694_1 1122599.AUGR01000001_gene296 7.66e-33 125.0 COG0464@1|root,COG0464@2|Bacteria,1QU82@1224|Proteobacteria,1SA9J@1236|Gammaproteobacteria,1XPV6@135619|Oceanospirillales 135619|Oceanospirillales O Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_195922_2 1692256.A0A0K1RL85_9CIRC 4.5e-136 390.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_86505_1 761193.Runsl_4413 9.19e-11 65.5 COG0338@1|root,COG0338@2|Bacteria,4NRXP@976|Bacteroidetes 976|Bacteroidetes L DNA N-6-adenine-methyltransferase (Dam) - - - - - - - - - - - - Dam k59_86642_1 1385658.U5KNR1_9VIRU 5.17e-70 227.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_62671_4 1234888.K0A2J2_9VIRU 2.27e-147 437.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_74672_1 1121459.AQXE01000015_gene277 2.95e-09 65.1 COG5434@1|root,COG5434@2|Bacteria,1PGI5@1224|Proteobacteria,435Q3@68525|delta/epsilon subdivisions,2X046@28221|Deltaproteobacteria,2MAEU@213115|Desulfovibrionales 28221|Deltaproteobacteria M Belongs to the glycosyl hydrolase 28 family - - - - - - - - - - - - - k59_147482_3 1161935.H9D1D6_9CAUD 6.99e-37 134.0 4QFN8@10239|Viruses,4QYWE@35237|dsDNA viruses no RNA stage,4QS52@28883|Caudovirales,4QP1K@10744|Podoviridae 10744|Podoviridae S metal ion binding - - - - - - - - - - - - - k59_197181_2 1437882.AZRU01000034_gene459 2.68e-39 147.0 28JXH@1|root,2ZA3Z@2|Bacteria,1R8CZ@1224|Proteobacteria,1TC26@1236|Gammaproteobacteria,1YJPC@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_38944_2 742740.HMPREF9474_02276 1.19e-20 86.7 2BD7A@1|root,326VE@2|Bacteria,1USRB@1239|Firmicutes,25ASG@186801|Clostridia,223BG@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_38944_3 411460.RUMTOR_01352 2.31e-53 172.0 2AIHK@1|root,318ZG@2|Bacteria,1V7P0@1239|Firmicutes,24KNU@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_38944_8 691965.D4P7C5_9CAUD 4.21e-44 157.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_245599_2 1042209.HK44_020560 8.42e-135 397.0 2CYA9@1|root,32T3V@2|Bacteria,1RGRN@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_14153_4 396595.TK90_2683 6.11e-19 87.4 COG0237@1|root,COG0237@2|Bacteria,1NE9C@1224|Proteobacteria,1SCJ4@1236|Gammaproteobacteria 1236|Gammaproteobacteria H dephospho-CoA kinase activity - - - - - - - - - - - - - k59_63871_1 1246484.D479_07157 5.13e-30 121.0 COG5377@1|root,COG5377@2|Bacteria,1TS2Y@1239|Firmicutes,4HAFK@91061|Bacilli 91061|Bacilli L Phage-related protein yqaJ - - - - - - - - - - - YqaJ k59_283228_8 1236542.BALM01000007_gene3464 1.23e-76 275.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase - - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 k59_319123_1 932213.SPM24T3_17360 8.63e-72 231.0 COG4227@1|root,COG4227@2|Bacteria,1MU8I@1224|Proteobacteria,1RNU7@1236|Gammaproteobacteria,4018J@613|Serratia 1236|Gammaproteobacteria L Domain of unknown function (DUF1738) traC - - - - - - - - - - - DUF1738,Toprim_4 k59_38946_3 1110502.TMO_0053 2.45e-08 58.9 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,2TT3N@28211|Alphaproteobacteria,2JQ8P@204441|Rhodospirillales 204441|Rhodospirillales S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_197295_2 1192868.CAIU01000008_gene967 3.91e-37 130.0 COG1738@1|root,COG1738@2|Bacteria,1RDSF@1224|Proteobacteria 1224|Proteobacteria S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage - - - ko:K09125 - - - - ko00000 - - - Vut_1 k59_209849_3 398578.Daci_3225 7.27e-18 79.0 2EI4V@1|root,33BW7@2|Bacteria,1NN3Z@1224|Proteobacteria 1224|Proteobacteria S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_38951_1 105154.Q9MBU6_9VIRU 4.5e-96 297.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_160934_1 585423.KR49_09340 8.49e-16 79.3 COG2227@1|root,COG2227@2|Bacteria 2|Bacteria H 3-demethylubiquinone-9 3-O-methyltransferase activity - - 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31 k59_368322_6 105154.Q9MBU6_9VIRU 1.87e-114 347.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_15359_2 1192868.CAIU01000008_gene967 1.15e-63 201.0 COG1738@1|root,COG1738@2|Bacteria,1RDSF@1224|Proteobacteria 1224|Proteobacteria S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage - - - ko:K09125 - - - - ko00000 - - - Vut_1 k59_15359_3 1229485.AMYV01000092_gene800 8.42e-38 136.0 28J67@1|root,2Z91Y@2|Bacteria,1R7RG@1224|Proteobacteria,1RZB8@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_356468_1 247490.KSU1_C0231 7.15e-35 133.0 2CDQ7@1|root,2Z7KV@2|Bacteria,2J41Q@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_137546_3 179237.Q8W6J4_9CAUD 2.1e-20 107.0 4QBNM@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPEZ@28883|Caudovirales 28883|Caudovirales S Cell Wall Hydrolase - - - - - - - - - - - - - k59_101496_1 1234888.K0A2J2_9VIRU 2.94e-47 170.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_320510_1 1788444.A0A190WHA5_9CIRC 5.25e-41 149.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_4484_3 186617.M9M8L2_9VIRU 1.32e-46 167.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_28696_1 861299.J421_3557 2.96e-16 77.0 COG0629@1|root,COG0629@2|Bacteria,1ZTPB@142182|Gemmatimonadetes 142182|Gemmatimonadetes L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_28696_2 1123368.AUIS01000020_gene1078 3.9e-14 73.9 28XPA@1|root,2ZJK5@2|Bacteria,1P9T2@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_308185_1 349106.PsycPRwf_1520 2.32e-110 338.0 COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,1RQ01@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Nitric oxide reductase norB - 1.7.2.5 ko:K04561 ko00910,ko01120,map00910,map01120 M00529 R00294 RC02794 ko00000,ko00001,ko00002,ko01000 3.D.4.10 - - COX1 k59_40384_1 1210884.HG799466_gene12718 8.13e-99 305.0 COG4653@1|root,COG4653@2|Bacteria,2J062@203682|Planctomycetes 203682|Planctomycetes S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_344457_2 272560.BPSL1666 9.09e-59 206.0 COG0457@1|root,COG0500@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,COG2226@2|Bacteria,1MUZK@1224|Proteobacteria,2VJNV@28216|Betaproteobacteria,1K0WR@119060|Burkholderiaceae 28216|Betaproteobacteria M repeat-containing protein - - - - - - - - - - - - Glyco_transf_9,TPR_1,TPR_16 k59_247161_2 742727.HMPREF9447_01719 7.25e-40 149.0 COG1032@1|root,COG1032@2|Bacteria,4NZ46@976|Bacteroidetes,2FNXU@200643|Bacteroidia,4APA0@815|Bacteroidaceae 976|Bacteroidetes C radical SAM domain protein - - - - - - - - - - - - - k59_40385_1 1230476.C207_01166 8.51e-61 201.0 28PTM@1|root,2ZCEU@2|Bacteria,1R5DD@1224|Proteobacteria,2TVG7@28211|Alphaproteobacteria,3JU4C@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_224705_4 1123508.JH636454_gene5706 2.97e-16 85.9 COG0438@1|root,COG1216@1|root,COG3914@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,COG3914@2|Bacteria,2J0FG@203682|Planctomycetes 203682|Planctomycetes O Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2,Methyltransf_21 k59_321969_3 186617.M9M8L2_9VIRU 1.63e-42 153.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_163812_3 105154.Q9MBU0_9VIRU 2.62e-40 151.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_163812_4 1986029.Q9MBM6_9VIRU 2.05e-13 71.2 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_163812_6 105154.Q9MBU6_9VIRU 2.74e-126 386.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_114774_1 1215092.PA6_009_00220 1.04e-19 97.8 291GM@1|root,2ZP3A@2|Bacteria,1RD1E@1224|Proteobacteria,1S4X6@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_357833_2 467481.B0VK85_9CAUD 3.11e-36 133.0 4QGDF@10239|Viruses,4R0KW@35237|dsDNA viruses no RNA stage,4QSIJ@28883|Caudovirales,4QMJY@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_369792_1 562742.F4YXT5_9CAUD 1.88e-70 229.0 4QB9S@10239|Viruses,4QUXK@35237|dsDNA viruses no RNA stage,4QPW1@28883|Caudovirales,4QM6J@10699|Siphoviridae 10699|Siphoviridae S Phage major capsid protein E - GO:0005575,GO:0019012,GO:0019028,GO:0019030,GO:0039620,GO:0044423 - - - - - - - - - - - k59_333952_1 1121451.DESAM_22835 8.53e-10 58.9 2DZ82@1|root,32V6V@2|Bacteria,1N3UK@1224|Proteobacteria,431CX@68525|delta/epsilon subdivisions,2WX13@28221|Deltaproteobacteria,2M9YP@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - Tube k59_16811_1 1283079.M1ID95_9CAUD 2.14e-32 129.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_151592_2 1358423.N180_02820 6.49e-07 53.1 2E8S0@1|root,3332X@2|Bacteria,4NWIA@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - k59_54274_1 570952.ATVH01000011_gene340 5.09e-10 66.2 COG0503@1|root,COG1040@1|root,COG0503@2|Bacteria,COG1040@2|Bacteria,1QV41@1224|Proteobacteria 1224|Proteobacteria F acetyltransferase - - - - - - - - - - - - - k59_357845_1 691965.D4P7I3_9CAUD 1.45e-73 248.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_176143_1 768710.DesyoDRAFT_0324 7.26e-06 49.7 COG5663@1|root,COG5663@2|Bacteria,1V2IT@1239|Firmicutes,24MK8@186801|Clostridia,2624R@186807|Peptococcaceae 186801|Clostridia S PFAM 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) - - - ko:K05967 - - - - ko00000 - - - NT5C k59_176143_2 953739.SVEN_2161 1.31e-09 62.8 COG0739@1|root,COG0739@2|Bacteria,2GW9V@201174|Actinobacteria 201174|Actinobacteria M heme binding - - - - - - - - - - - - Amidase_2 k59_297598_1 270374.MELB17_17073 4e-25 114.0 COG0582@1|root,COG0582@2|Bacteria,1MVZB@1224|Proteobacteria,1RP4Y@1236|Gammaproteobacteria,468HY@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family int - - ko:K14059 - - - - ko00000 - - - Arm-DNA-bind_2,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase k59_369798_2 266117.Rxyl_2444 3.89e-06 51.6 COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,4CP73@84995|Rubrobacteria 84995|Rubrobacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 k59_214716_2 205914.HS_1394 4.47e-12 66.2 COG1403@1|root,COG1403@2|Bacteria,1RHFB@1224|Proteobacteria,1S4HW@1236|Gammaproteobacteria,1Y9ZP@135625|Pasteurellales 135625|Pasteurellales V Bacteriophage Lambda NinG protein - - - - - - - - - - - - NinG k59_347653_1 105154.Q9MBU3_9VIRU 2.87e-10 62.0 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_31921_2 1788454.A0A190WHE4_9CIRC 3.63e-35 133.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_68398_1 1504981.KO116_0348 8.57e-17 84.0 COG4128@1|root,COG4128@2|Bacteria,1REHG@1224|Proteobacteria,1S491@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_288633_1 106648.BBLJ01000014_gene1425 3.15e-39 141.0 COG3206@1|root,COG3206@2|Bacteria,1ND5H@1224|Proteobacteria,1RNXC@1236|Gammaproteobacteria,3NSVB@468|Moraxellaceae 1236|Gammaproteobacteria M protein involved in exopolysaccharide biosynthesis - - - - - - - - - - - - Rad52_Rad22 k59_237848_1 1385658.U5KPZ6_9VIRU 1.47e-72 239.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_214720_1 691965.D4P7I3_9CAUD 5.11e-133 419.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_201776_1 363253.LI0182 3.07e-23 101.0 2C9JF@1|root,32RPD@2|Bacteria,1N8CG@1224|Proteobacteria,42REW@68525|delta/epsilon subdivisions,2WNQ1@28221|Deltaproteobacteria,2MB30@213115|Desulfovibrionales 28221|Deltaproteobacteria S ERF superfamily - - - - - - - - - - - - ERF k59_80342_1 344747.PM8797T_10969 2.96e-08 55.8 COG1974@1|root,COG1974@2|Bacteria 2|Bacteria K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - HSDR_N_2,LexA_DNA_bind,Peptidase_S24,UvrD-helicase,UvrD_C k59_226660_3 1385658.U5KPZ6_9VIRU 7.3e-199 571.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_226660_5 1165094.RINTHH_3920 8.17e-77 244.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_19947_1 1609634.A0A0C5AFV4_9VIRU 3.29e-46 162.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_19947_4 1609634.A0A0C5AFT2_9VIRU 8.39e-132 385.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_82371_2 522373.Smlt1917 0.000265 47.8 2DS9K@1|root,33F5E@2|Bacteria,1NECJ@1224|Proteobacteria,1SF4N@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_290478_1 1112212.JH584235_gene738 3.01e-07 62.4 COG1196@1|root,COG1196@2|Bacteria,1N5IT@1224|Proteobacteria,2TZ1S@28211|Alphaproteobacteria,2K5IE@204457|Sphingomonadales 204457|Sphingomonadales D nuclear chromosome segregation - - - - - - - - - - - - - k59_106336_1 357276.EL88_22665 3.94e-29 110.0 COG3108@1|root,COG3108@2|Bacteria,4NW30@976|Bacteroidetes,2FSX2@200643|Bacteroidia,4AR8E@815|Bacteroidaceae 976|Bacteroidetes S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k59_82372_2 1609634.A0A0C5AFT2_9VIRU 3.49e-20 96.3 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_143079_1 1622190.A0A0E3T5U7_9CAUD 1.31e-62 217.0 4QKP3@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_131241_2 1676988.A0A0H4FV52_9CIRC 8.16e-15 76.3 4QGVY@10239|Viruses,4QUKN@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_290484_2 1567012.A0A0A7RTE7_9VIRU 8.77e-73 235.0 4QEFV@10239|Viruses 10239|Viruses S Pfam:Terminase_3C - - - - - - - - - - - - - k59_252181_2 1114179.I2FLR4_9CAUD 7.26e-09 58.9 4QFN3@10239|Viruses,4QZSZ@35237|dsDNA viruses no RNA stage,4QQ4M@28883|Caudovirales,4QNXC@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_57889_1 994573.T472_0213960 2.58e-18 92.0 COG2887@1|root,COG2887@2|Bacteria,1TPIC@1239|Firmicutes,247TB@186801|Clostridia,36EZ3@31979|Clostridiaceae 186801|Clostridia L Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_325809_1 1141137.K4F7X5_9CAUD 4.08e-21 96.3 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_373441_3 214092.YPO2274 9.25e-26 105.0 2CEG2@1|root,2ZCEX@2|Bacteria,1RB74@1224|Proteobacteria,1S2JC@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage replication protein CRI - - - - - - - - - - - - Phage_CRI,Phage_X k59_155481_1 365044.Pnap_3327 7.16e-11 64.3 COG0640@1|root,COG0640@2|Bacteria,1RHDS@1224|Proteobacteria,2VWR7@28216|Betaproteobacteria 28216|Betaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_36 k59_155481_2 1120956.JHZK01000002_gene905 4.28e-15 75.1 COG0593@1|root,COG0593@2|Bacteria,1P7AH@1224|Proteobacteria,2UXII@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Bacterial dnaA protein helix-turn-helix - - - - - - - - - - - - Bac_DnaA_C k59_20190_1 1548903.A0A0A1IUX7_9CAUD 5.57e-24 97.4 4QC79@10239|Viruses,4QRTA@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_218714_1 136084.Q9G0G8_9CAUD 1.24e-39 143.0 4QGZN@10239|Viruses,4R0FF@35237|dsDNA viruses no RNA stage,4QTUK@28883|Caudovirales,4QNE5@10744|Podoviridae 10744|Podoviridae S nuclease activity - - - - - - - - - - - - - k59_278201_1 570952.ATVH01000005_gene1168 5.32e-17 86.3 COG3391@1|root,COG3391@2|Bacteria,1MXN7@1224|Proteobacteria,2TR83@28211|Alphaproteobacteria,2JWNC@204441|Rhodospirillales 204441|Rhodospirillales S Putative phage tail protein - - - - - - - - - - - - Phage-tail_3 k59_119847_1 411460.RUMTOR_01342 4.13e-12 64.7 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_119847_3 411460.RUMTOR_01344 3.31e-18 78.2 2E2Y0@1|root,32XYV@2|Bacteria,1VD9S@1239|Firmicutes,24PK0@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_303360_1 1082932.ATCR1_06741 3.69e-36 143.0 COG5323@1|root,COG5323@2|Bacteria,1R049@1224|Proteobacteria 1224|Proteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6 k59_351388_1 1609634.A0A0C5AFV4_9VIRU 2.2e-72 236.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_230522_1 857087.Metme_2331 5.71e-44 158.0 COG4128@1|root,COG4128@2|Bacteria,1N0I7@1224|Proteobacteria,1TBAY@1236|Gammaproteobacteria,1XG0Y@135618|Methylococcales 135618|Methylococcales S PFAM Zonular occludens toxin - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_265590_1 1618248.A0A0C5IB82_9CIRC 2.01e-15 77.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_168701_3 78245.Xaut_3722 2.06e-07 54.7 2FEUE@1|root,346TC@2|Bacteria,1MZPB@1224|Proteobacteria,2UC4Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_189878_2 1100721.ALKO01000041_gene5 1.55e-22 99.4 2EZCX@1|root,33SI7@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_265738_1 460265.Mnod_4282 3.09e-27 114.0 COG3740@1|root,COG3740@2|Bacteria,1QVIJ@1224|Proteobacteria,2TVIM@28211|Alphaproteobacteria,1JX89@119045|Methylobacteriaceae 28211|Alphaproteobacteria S PFAM peptidase U35 phage prohead HK97 - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_108383_1 1234888.K0A2J2_9VIRU 8.89e-90 285.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_339794_1 55952.BU52_00745 1.91e-08 60.5 COG3757@1|root,COG3757@2|Bacteria,2GKS0@201174|Actinobacteria 201174|Actinobacteria M lysozyme - - - - - - - - - - - - Glyco_hydro_25 k59_10782_1 69279.BG36_20870 5.78e-107 332.0 COG3170@1|root,COG3170@2|Bacteria,1QVEE@1224|Proteobacteria,2TWDG@28211|Alphaproteobacteria 28211|Alphaproteobacteria NU Phage P22-like portal protein - - - - - - - - - - - - P22_portal k59_22079_1 1609634.A0A0C5AFV4_9VIRU 2.51e-197 563.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_193803_2 630626.EBL_c28400 1.06e-05 51.2 2DKZC@1|root,30ZS6@2|Bacteria,1RGQ9@1224|Proteobacteria,1S70S@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_193845_1 557598.LHK_01542 5.64e-76 240.0 28HXV@1|root,2Z83C@2|Bacteria,1PJBP@1224|Proteobacteria,2VZV5@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_48665_1 742727.HMPREF9447_04874 4.4e-44 154.0 COG0863@1|root,COG0863@2|Bacteria,4NQQ1@976|Bacteroidetes,2G1PS@200643|Bacteroidia,4ARBB@815|Bacteroidaceae 976|Bacteroidetes L DNA methylase - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_243070_1 105154.Q9MBU6_9VIRU 1.18e-67 224.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_230906_3 1385658.U5KPZ6_9VIRU 1.44e-180 525.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_230906_4 105154.Q9MBU3_9VIRU 0.000243 48.5 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_133702_3 1128073.G9LQV6_9CIRC 1.45e-38 146.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_376752_1 1237500.ANBA01000003_gene4742 4.88e-35 139.0 COG4695@1|root,COG4695@2|Bacteria,2GZFX@201174|Actinobacteria 201174|Actinobacteria S Phage portal protein - - - - - - - - - - - - Phage_portal k59_376752_3 479431.Namu_3485 1.66e-21 103.0 COG4626@1|root,COG4626@2|Bacteria,2IB7D@201174|Actinobacteria,4EWMZ@85013|Frankiales 201174|Actinobacteria S Terminase - - - - - - - - - - - - Terminase_1,Terminase_3,Terminase_6 k59_60818_1 691965.D4P7L7_9CAUD 2.14e-259 749.0 4QB9J@10239|Viruses,4QXFE@35237|dsDNA viruses no RNA stage,4QS1Z@28883|Caudovirales,4QN8F@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_60818_2 691965.D4P7L6_9CAUD 1.62e-66 208.0 4QFKG@10239|Viruses,4QV77@35237|dsDNA viruses no RNA stage,4QR6Q@28883|Caudovirales,4QMGT@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_60818_3 691965.D4P7L5_9CAUD 3.25e-32 115.0 4QG3V@10239|Viruses,4QW5T@35237|dsDNA viruses no RNA stage,4QSWE@28883|Caudovirales,4QM1Q@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_12214_1 1123242.JH636434_gene4506 1.47e-12 76.6 COG0464@1|root,COG0464@2|Bacteria,2IXZF@203682|Planctomycetes 203682|Planctomycetes O COG0464 ATPases of the AAA class - - - - - - - - - - - - AAA k59_352856_1 1618237.A0A0C5IMG6_9CIRC 2.27e-39 145.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_316352_2 1385658.U5KPZ6_9VIRU 1.27e-198 571.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_316352_6 1609634.A0A0C5AFT2_9VIRU 1.19e-59 200.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_267562_1 398767.Glov_2811 3.34e-21 94.0 COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria 1224|Proteobacteria M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - - - - - - - - - - Rod-binding,SLT k59_170350_1 1540098.A0A0A0RTJ1_9CAUD 1.07e-64 207.0 4QCT7@10239|Viruses,4QPFU@28883|Caudovirales,4QKS9@10699|Siphoviridae 10699|Siphoviridae S iron-sulfur cluster binding - - - - - - - - - - - - - k59_170350_2 460265.Mnod_6264 2.13e-76 239.0 COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,2TU7F@28211|Alphaproteobacteria,1JXA2@119045|Methylobacteriaceae 28211|Alphaproteobacteria F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) - - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC k59_170350_3 879243.Poras_1677 3.56e-53 172.0 COG0720@1|root,COG0720@2|Bacteria,4PIUG@976|Bacteroidetes,2FSF1@200643|Bacteroidia,22Z05@171551|Porphyromonadaceae 976|Bacteroidetes H 6-pyruvoyl tetrahydrobiopterin synthase queD - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS k59_170350_4 1538804.A0A088F7Y4_9CAUD 3.9e-39 139.0 4QH75@10239|Viruses,4QQZ4@28883|Caudovirales,4QKSF@10699|Siphoviridae 10699|Siphoviridae S GTP cyclohydrolase I activity - - - - - - - - - - - - - k59_352858_1 1692244.A0A0K1RLR5_9CIRC 4.46e-30 120.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_219245_4 1042163.BRLA_07p000010 4.7e-05 51.2 28KEB@1|root,3063N@2|Bacteria,1TZ4V@1239|Firmicutes,4I8BZ@91061|Bacilli,273D7@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - k59_194861_1 1123326.JFBL01000002_gene1658 9.16e-30 129.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2YMQV@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_316353_1 1196324.A374_01959 6.5e-14 75.5 COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,4HB9Q@91061|Bacilli 91061|Bacilli D Peptidase, M23 - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 k59_36890_1 426355.Mrad2831_5696 1.09e-47 166.0 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,2TV42@28211|Alphaproteobacteria,1JWXQ@119045|Methylobacteriaceae 28211|Alphaproteobacteria S terminase, large subunit - - - ko:K06909 - - - - ko00000 - - - Terminase_3 k59_36890_2 1144310.PMI07_002381 2.9e-08 55.1 2DTAB@1|root,33JEU@2|Bacteria,1NNYR@1224|Proteobacteria,2UKBA@28211|Alphaproteobacteria,4BG36@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_231226_1 1475143.W8SNN0_9CIRC 1.87e-22 98.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_304261_1 1122201.AUAZ01000017_gene2947 1.43e-48 176.0 COG0749@1|root,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,465DD@72275|Alteromonadaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - - - - - - - - - - - DNA_pol_A k59_97579_1 7220.FBpp0141925 5.31e-06 52.4 2CMNT@1|root,2QR3D@2759|Eukaryota,39UHX@33154|Opisthokonta,3B9U3@33208|Metazoa,3D2YM@33213|Bilateria,4201I@6656|Arthropoda,3SN7B@50557|Insecta,4553X@7147|Diptera,45X9Q@7214|Drosophilidae 33208|Metazoa G N-acetylmuramoyl-L-alanine amidase activity. It is involved in the biological process described with peptidoglycan catabolic process - GO:0000270,GO:0002376,GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0005488,GO:0005539,GO:0005575,GO:0005576,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006950,GO:0006952,GO:0006955,GO:0008150,GO:0008152,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0016787,GO:0016810,GO:0016811,GO:0030203,GO:0031347,GO:0031348,GO:0042834,GO:0043170,GO:0045087,GO:0045088,GO:0045824,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0061783,GO:0065007,GO:0071704,GO:0080134,GO:0097367,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K01446 - - R04112 RC00064,RC00141 ko00000 - - - Amidase_2 k59_24733_1 105154.Q9MBU3_9VIRU 1.22e-16 79.0 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_24733_2 1385658.U5KPZ6_9VIRU 3.15e-19 87.8 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_292019_3 1385658.U5KPZ6_9VIRU 9.98e-42 153.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_340541_1 322855.Q52PM1_9CAUD 1.17e-29 117.0 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_109772_2 105154.Q9MBU3_9VIRU 1.38e-10 65.9 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_280022_3 1238450.VIBNISOn1_550017 4.83e-28 106.0 COG2852@1|root,COG2852@2|Bacteria,1N2UX@1224|Proteobacteria,1TIHC@1236|Gammaproteobacteria,1XZ4M@135623|Vibrionales 135623|Vibrionales S Protein conserved in bacteria - - - - - - - - - - - - - k59_280022_4 335283.Neut_1455 2.76e-175 552.0 COG2304@1|root,COG4733@1|root,COG2304@2|Bacteria,COG4733@2|Bacteria,1MXB4@1224|Proteobacteria,2VJS7@28216|Betaproteobacteria 28216|Betaproteobacteria M Putative phage tail protein - - - - - - - - - - - - Phage-tail_3 k59_280022_5 335283.Neut_1456 9.32e-17 74.3 2EK40@1|root,33DUE@2|Bacteria,1NJE0@1224|Proteobacteria,2W5HA@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_280022_6 335283.Neut_1457 1.09e-25 97.1 2CJX7@1|root,32W32@2|Bacteria,1N82M@1224|Proteobacteria,2VY34@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_280022_7 1397284.AYMN01000070_gene2146 3.51e-22 100.0 COG5449@1|root,COG5449@2|Bacteria,1MXK2@1224|Proteobacteria,1S5T3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage conserved hypothetical protein BR0599 - - - - - - - - - - - - DUF2163,Phage_BR0599 k59_280022_10 335283.Neut_1460 1.62e-64 238.0 COG1196@1|root,COG1345@1|root,COG1196@2|Bacteria,COG1345@2|Bacteria,1PDRQ@1224|Proteobacteria,2W14R@28216|Betaproteobacteria 28216|Betaproteobacteria D Prophage tail length tape measure protein - - - - - - - - - - - - TMP_2 k59_280022_11 443152.MDG893_20574 1.04e-41 140.0 2CHRA@1|root,32S6D@2|Bacteria,1MZ8I@1224|Proteobacteria,1SHSQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage tail assembly chaperone, TAC - - - - - - - - - - - - Phage_TAC_13 k59_280022_12 932213.SPM24T3_24191 3.64e-57 183.0 2DNA4@1|root,32WDI@2|Bacteria,1RFBA@1224|Proteobacteria,1T5E0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage tail tube, TTP, lambda-like - - - - - - - - - - - - Phage_TTP_11 k59_280022_13 443152.MDG893_20584 2.38e-43 145.0 2DM6W@1|root,32UGB@2|Bacteria,1N425@1224|Proteobacteria,1SB1W@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3168) - - - - - - - - - - - - DUF3168 k59_280022_14 1123279.ATUS01000005_gene3105 8.75e-41 142.0 2DNB5@1|root,32WIW@2|Bacteria,1N0BM@1224|Proteobacteria,1S8UT@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacteriophage HK97-gp10, putative tail-component - - - - - - - - - - - - HK97-gp10_like k59_256093_1 1234888.K0A2J2_9VIRU 6.83e-40 150.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_329062_2 1788454.A0A190WHE4_9CIRC 2.67e-48 169.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_98145_1 1150626.PHAMO_180128 2.71e-19 92.0 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,2TVGJ@28211|Alphaproteobacteria,2JPR0@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_159122_1 428125.CLOLEP_01379 2.62e-51 178.0 COG0553@1|root,COG0553@2|Bacteria,1TS9W@1239|Firmicutes,24CGX@186801|Clostridia,3WN6X@541000|Ruminococcaceae 186801|Clostridia KL Helicase conserved C-terminal domain - - - - - - - - - - - - - k59_159122_2 1476888.X4YH18_9CAUD 3.85e-17 77.0 4QG3V@10239|Viruses,4QW5T@35237|dsDNA viruses no RNA stage,4QSWE@28883|Caudovirales,4QM1Q@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_12958_1 1692252.A0A0K1RL35_9CIRC 4.95e-67 212.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_12958_4 1692255.A0A0K1RL52_9CIRC 5.95e-82 251.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_341142_10 1609634.A0A0C5AFV4_9VIRU 1.05e-153 452.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_86031_2 469381.Dpep_0394 6.75e-26 103.0 COG0817@1|root,COG0817@2|Bacteria,3TCBE@508458|Synergistetes 508458|Synergistetes L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group - - - - - - - - - - - - - k59_86031_5 316274.Haur_1384 5.82e-58 207.0 COG4373@1|root,COG4373@2|Bacteria 2|Bacteria - - gp17a - - ko:K06909 - - - - ko00000 - - - Terminase_6,Terminase_6C k59_74030_4 1234888.K0A2J2_9VIRU 7.9e-124 371.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_293728_3 1410632.JHWW01000005_gene815 4.12e-18 88.6 COG3723@1|root,COG3723@2|Bacteria,1UNDF@1239|Firmicutes,24CI5@186801|Clostridia,27R6Z@186928|unclassified Lachnospiraceae 186801|Clostridia L RecT family recT - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_38333_1 1380394.JADL01000001_gene2581 1.76e-19 90.1 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,2U1P9@28211|Alphaproteobacteria,2JX6C@204441|Rhodospirillales 204441|Rhodospirillales S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_196527_1 1502851.FG93_03501 4.06e-28 110.0 2AGTB@1|root,3171D@2|Bacteria,1RJGM@1224|Proteobacteria,2UJ68@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_135560_1 105154.Q9MBU3_9VIRU 1.97e-09 62.0 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_50675_2 1692244.A0A0K1RLR5_9CIRC 3.99e-82 255.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_13528_6 314230.DSM3645_28792 0.000334 53.5 COG1357@1|root,COG1357@2|Bacteria,2J2VS@203682|Planctomycetes 203682|Planctomycetes S PFAM Pentapeptide repeats (8 copies) - - - - - - - - - - - - - k59_210040_1 1379858.N508_02047 1.68e-32 121.0 COG0522@1|root,COG0522@2|Bacteria,2GF55@200930|Deferribacteres 200930|Deferribacteres J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD - - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 k59_210040_2 1499967.BAYZ01000114_gene2905 1.04e-27 105.0 COG0100@1|root,COG0100@2|Bacteria,2NPCN@2323|unclassified Bacteria 2|Bacteria J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 k59_270137_3 1538644.KO02_21560 9.2e-14 71.2 2DT8X@1|root,32UUQ@2|Bacteria,4NSYW@976|Bacteroidetes,1ITJW@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_319266_3 1123399.AQVE01000042_gene1324 3.05e-05 55.1 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,1RXX2@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N k59_343258_1 436308.Nmar_1073 7.23e-05 50.4 COG3794@1|root,arCOG05978@1|root,arCOG07813@1|root,arCOG02926@2157|Archaea,arCOG05978@2157|Archaea,arCOG07813@2157|Archaea 2157|Archaea C LamG domain protein jellyroll fold domain protein - - 2.7.11.1 ko:K12567 ko05410,ko05414,map05410,map05414 - - - ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812 - - - Copper-bind,GSDH,Laminin_G_3,ThuA,fn3 k59_343262_1 1379725.S5SYG4_9CIRC 1.14e-21 95.1 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_14492_1 1385658.U5KPZ6_9VIRU 1.02e-109 336.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_379828_8 1121930.AQXG01000007_gene454 2.37e-16 80.5 2E0FE@1|root,32W1M@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF932 k59_355556_1 1788452.A0A190WHG0_9CIRC 5.96e-49 171.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_307159_1 349161.Dred_1404 8.79e-15 79.0 2EYIP@1|root,33RSF@2|Bacteria,1VSNU@1239|Firmicutes,24YEW@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_136684_1 1121017.AUFG01000041_gene749 1.76e-87 271.0 COG0582@1|root,COG0582@2|Bacteria,2GMSF@201174|Actinobacteria,4FIIN@85021|Intrasporangiaceae 201174|Actinobacteria L Phage integrase family - - - - - - - - - - - - Phage_integrase k59_162347_2 1385658.U5KPZ6_9VIRU 1.25e-62 210.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_284987_1 1304275.C41B8_05368 1.19e-49 179.0 28S81@1|root,2ZEJD@2|Bacteria,1RCNN@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_126027_3 1524880.A0A076GC93_9VIRU 3.48e-43 159.0 4QAK6@10239|Viruses 10239|Viruses S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_126027_4 883156.HMPREF9282_00554 1.29e-06 58.2 2EVCH@1|root,33NSZ@2|Bacteria,1W370@1239|Firmicutes,4H8MI@909932|Negativicutes 909932|Negativicutes - - - - - - - - - - - - - - - k59_101779_1 411483.FAEPRAA2165_01501 2.31e-11 69.7 COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,2495S@186801|Clostridia 186801|Clostridia L Virulence-associated protein E - - - - - - - - - - - - VirE k59_235155_1 1234888.K0A2J2_9VIRU 1.36e-91 286.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_332688_5 1168478.I6R9L7_9CAUD 3.21e-07 56.6 4QBFR@10239|Viruses,4QV1E@35237|dsDNA viruses no RNA stage,4QPRX@28883|Caudovirales,4QKMP@10699|Siphoviridae 10699|Siphoviridae S ERF superfamily - - - - - - - - - - - - - k59_332688_6 1121382.JQKG01000001_gene2497 3.49e-61 216.0 COG0210@1|root,COG0210@2|Bacteria,1WN9U@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L UvrD-like helicase C-terminal domain - - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k59_28921_1 691965.D4P7D6_9CAUD 1.1e-22 101.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_356757_3 323261.Noc_3023 2.44e-54 175.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,1WY0C@135613|Chromatiales 135613|Chromatiales L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_285172_2 28072.Nos7524_2522 2.17e-33 123.0 COG1898@1|root,COG1898@2|Bacteria,1G0QA@1117|Cyanobacteria,1HMAV@1161|Nostocales 1117|Cyanobacteria M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose rfbC - 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - dTDP_sugar_isom k59_28931_1 338966.Ppro_2157 1.42e-08 63.5 COG4932@1|root,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,42RZP@68525|delta/epsilon subdivisions,2X7KQ@28221|Deltaproteobacteria,43SHG@69541|Desulfuromonadales 28221|Deltaproteobacteria M domain protein - - - - - - - - - - - - - k59_137973_1 1176423.I6RTS1_9VIRU 2.3e-27 111.0 4QECI@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_381107_3 1385658.U5KNR1_9VIRU 7.68e-72 232.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_185191_2 935836.JAEL01000005_gene2721 6.27e-13 66.2 COG1591@1|root,COG1591@2|Bacteria,1V9FG@1239|Firmicutes,4HSSG@91061|Bacilli 91061|Bacilli L VRR_NUC - - - - - - - - - - - - - k59_185191_3 331113.SNE_A20230 1.1e-13 81.6 COG0553@1|root,COG0553@2|Bacteria,2JFGJ@204428|Chlamydiae 204428|Chlamydiae KL SNF2 family N-terminal domain CP_1034 - - - - - - - - - - - Helicase_C,SNF2_N,SWIM k59_126221_1 375286.mma_2206 3.84e-28 113.0 COG5323@1|root,COG5323@2|Bacteria 2|Bacteria M Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6 k59_150189_1 136084.Q9G0F7_9CAUD 5.23e-167 500.0 4QH2I@10239|Viruses,4QWWD@35237|dsDNA viruses no RNA stage,4QQE9@28883|Caudovirales,4QNFX@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_151550_2 1416759.AYMR01000023_gene270 2.85e-08 56.6 COG3740@1|root,COG3740@2|Bacteria 2|Bacteria OU Phage prohead protease, HK97 family - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78 k59_236279_5 1120950.KB892822_gene590 9.16e-07 60.5 COG0553@1|root,COG0863@1|root,COG0553@2|Bacteria,COG0863@2|Bacteria,2H20C@201174|Actinobacteria,4DTBP@85009|Propionibacteriales 201174|Actinobacteria KL DEAD-like helicases superfamily - - - - - - - - - - - - Helicase_C,N6_N4_Mtase k59_16773_3 1454202.PPBDW_90555___1 8.19e-28 108.0 arCOG06669@1|root,2ZC1E@2|Bacteria,1RBUZ@1224|Proteobacteria,1S2MV@1236|Gammaproteobacteria,1Y11D@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k59_382181_1 29486.NJ56_14900 7.03e-51 176.0 COG0207@1|root,COG0207@2|Bacteria,1RA8U@1224|Proteobacteria,1S4IG@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Thymidylate synthase - - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k59_369754_1 411483.FAEPRAA2165_01444 4.84e-21 94.0 COG4422@1|root,COG4422@2|Bacteria,1TPP1@1239|Firmicutes,248RZ@186801|Clostridia,3WHGZ@541000|Ruminococcaceae 186801|Clostridia S Protein of unknown function (DUF5131) - - - - - - - - - - - - DUF4186,DUF5131 k59_333914_5 242527.Q6V7R6_9CAUD 4.6e-14 77.4 4QAX8@10239|Viruses,4QVB1@35237|dsDNA viruses no RNA stage,4QPHH@28883|Caudovirales 28883|Caudovirales S calcium ion binding - - - - - - - - - - - - - k59_333914_6 1175654.A0A0S0MVM4_9CAUD 2.06e-57 182.0 4QBB2@10239|Viruses,4QWCF@35237|dsDNA viruses no RNA stage,4QRAZ@28883|Caudovirales,4QKR3@10699|Siphoviridae 10699|Siphoviridae S 6-pyruvoyl tetrahydropterin synthase - - - - - - - - - - - - - k59_333914_7 1540098.A0A0A0RPC6_9CAUD 6.48e-31 119.0 4QGHR@10239|Viruses,4QTRG@28883|Caudovirales,4QKSH@10699|Siphoviridae 10699|Siphoviridae S Queuosine biosynthesis protein QueC - - - - - - - - - - - - - k59_66689_1 1609634.A0A0C5AFT2_9VIRU 1.96e-36 137.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_139319_2 1118153.MOY_16467 4.32e-76 250.0 28IN7@1|root,2Z8NM@2|Bacteria 2|Bacteria S Capsid protein (F protein) - - - - - - - - - - - - Phage_F k59_248599_2 1234888.K0A2R8_9VIRU 7.65e-44 158.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_30472_3 675812.VHA_000295 5.45e-12 66.6 2DMPB@1|root,32SV8@2|Bacteria,1NHUE@1224|Proteobacteria,1SIKI@1236|Gammaproteobacteria,1XY3E@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k59_176254_1 1126627.BAWE01000004_gene4279 3.67e-22 100.0 2DUMH@1|root,33R9V@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_42149_2 767817.Desgi_3096 1.98e-32 122.0 COG4422@1|root,COG4422@2|Bacteria,1TPRY@1239|Firmicutes,247VT@186801|Clostridia 186801|Clostridia F Psort location Cytoplasmic, score - - - - - - - - - - - - DUF5131 k59_248711_2 1122962.AULH01000009_gene3850 1.99e-23 117.0 2DKW9@1|root,30JFD@2|Bacteria,1QZ8U@1224|Proteobacteria,2U83R@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_139469_2 1007105.PT7_P073 8.44e-12 64.3 2CH99@1|root,32S5M@2|Bacteria,1N2GH@1224|Proteobacteria,2W6BX@28216|Betaproteobacteria 28216|Betaproteobacteria S Recombination enhancement, RecA-dependent nuclease - - - - - - - - - - - - RecA_dep_nuc k59_6033_3 1548903.A0A0A1IWQ8_9CAUD 4.21e-72 228.0 4QAIK@10239|Viruses,4QPEB@28883|Caudovirales 28883|Caudovirales S phosphoprotein phosphatase activity - - - - - - - - - - - - - k59_323518_2 278963.ATWD01000001_gene2335 9.49e-10 62.0 COG3864@1|root,COG3864@2|Bacteria,3Y8V6@57723|Acidobacteria 2|Bacteria S Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N k59_237658_2 666684.AfiDRAFT_1861 3.91e-12 71.6 28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TURR@28211|Alphaproteobacteria,3JUCC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_140846_2 1126411.I1TEL3_9CIRC 6.95e-25 104.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_214621_1 644107.SL1157_1635 8.35e-59 196.0 COG2404@1|root,COG2404@2|Bacteria,1PKY9@1224|Proteobacteria,2V2FR@28211|Alphaproteobacteria,4NDK2@97050|Ruegeria 28211|Alphaproteobacteria S hydrolase activity, acting on ester bonds - - - - - - - - - - - - - k59_214621_2 1027273.GZ77_09015 6.19e-72 228.0 28HHC@1|root,2Z7T2@2|Bacteria,1PZ57@1224|Proteobacteria,1SRT1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S AAA domain - - - - - - - - - - - - AAA_24 k59_335611_1 1609634.A0A0C5AFV4_9VIRU 8.17e-21 92.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_140940_1 1210884.HG799467_gene13131 1.04e-89 281.0 COG0553@1|root,COG0553@2|Bacteria 2|Bacteria L helicase activity - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_68294_1 335283.Neut_1455 2e-26 113.0 COG2304@1|root,COG4733@1|root,COG2304@2|Bacteria,COG4733@2|Bacteria,1MXB4@1224|Proteobacteria,2VJS7@28216|Betaproteobacteria 28216|Betaproteobacteria M Putative phage tail protein - - - - - - - - - - - - Phage-tail_3 k59_226596_2 1204539.J9QGS0_9CAUD 3.43e-09 63.5 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_335618_3 716928.AJQT01000109_gene1217 3.13e-15 71.2 2FEUE@1|root,346TC@2|Bacteria,1MZPB@1224|Proteobacteria,2UC4Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_129103_2 1121098.HMPREF1534_03916 9.16e-15 71.2 28P3F@1|root,2ZBZ4@2|Bacteria,4NMPC@976|Bacteroidetes,2FSJ3@200643|Bacteroidia,4AR09@815|Bacteroidaceae 976|Bacteroidetes - - - - - - - - - - - - - - - k59_347591_1 1504822.CCNO01000015_gene594 2.8e-89 290.0 COG0553@1|root,COG0863@1|root,COG0553@2|Bacteria,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_94967_2 686578.AFFX01000004_gene3959 6.88e-35 140.0 COG3391@1|root,COG3391@2|Bacteria,1MXN7@1224|Proteobacteria 1224|Proteobacteria M Gene transfer agent - - - - - - - - - - - - Phage-tail_3 k59_239533_1 36080.S2JV58 2.26e-78 251.0 COG0008@1|root,KOG1149@2759|Eukaryota,38CS1@33154|Opisthokonta,3NV5D@4751|Fungi,1GRUI@112252|Fungi incertae sedis 4751|Fungi J tRNA synthetases class I (E and Q), catalytic domain MSE1 GO:0000166,GO:0000959,GO:0003674,GO:0003824,GO:0004812,GO:0004818,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006424,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032543,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070127,GO:0070149,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140053,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - iMM904.YOL033W,iND750.YOL033W tRNA-synt_1c k59_131004_2 1173762.S4TT71_9CAUD 2.4e-08 59.3 4QAVB@10239|Viruses,4QPIJ@28883|Caudovirales,4QNHZ@10744|Podoviridae 10744|Podoviridae S Phage lysozyme - - - - - - - - - - - - - k59_385095_2 1120792.JAFV01000001_gene3544 3.46e-18 87.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria,36Z9P@31993|Methylocystaceae 28211|Alphaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_251931_1 935557.ATYB01000009_gene633 1.07e-135 400.0 COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,2U1ME@28211|Alphaproteobacteria,4BBT3@82115|Rhizobiaceae 28211|Alphaproteobacteria S tRNA-splicing ligase RtcB - - - - - - - - - - - - RtcB k59_70079_1 300852.55772280 1.19e-21 89.7 COG1694@1|root,COG1694@2|Bacteria,1WK7E@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S PFAM MazG nucleotide pyrophosphohydrolase - - - - - - - - - - - - MazG k59_70079_2 1227266.HMPREF1551_00543 0.000135 48.9 COG0237@1|root,COG0237@2|Bacteria,4P85U@976|Bacteroidetes 976|Bacteroidetes H dephospho-CoA kinase activity - - - - - - - - - - - - - k59_263716_2 1367847.JCM7686_1246 2.67e-29 112.0 2AGM0@1|root,316U7@2|Bacteria,1N0JZ@1224|Proteobacteria,2UC1Y@28211|Alphaproteobacteria,2PYVN@265|Paracoccus 28211|Alphaproteobacteria S Bacteriophage HK97-gp10, putative tail-component - - - - - - - - - - - - HK97-gp10_like k59_8943_1 938289.CAJN020000009_gene65 4.29e-32 135.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia 186801|Clostridia L DNA polymerase - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_276280_1 351016.RAZWK3B_16730 8.21e-19 92.4 COG1783@1|root,COG1783@2|Bacteria,1QZB1@1224|Proteobacteria,2TY6V@28211|Alphaproteobacteria 2|Bacteria S Terminase-like family - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_6 k59_155450_2 1238190.AMQY01000021_gene1593 5.72e-108 345.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,1S0Q1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L ORF located using Glimmer RBSfinder - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_82350_2 1239384.K4MPY5_9CAUD 5.36e-11 64.7 4QCCZ@10239|Viruses,4QYIM@35237|dsDNA viruses no RNA stage,4QQNX@28883|Caudovirales 28883|Caudovirales S virion - - - - - - - - - - - - - k59_82350_3 411460.RUMTOR_01353 4.7e-16 73.2 2CGGA@1|root,345NF@2|Bacteria,1VZU0@1239|Firmicutes,253ZW@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_156715_1 343509.SG0727 7.37e-84 261.0 COG0270@1|root,COG0270@2|Bacteria,1NPQG@1224|Proteobacteria,1S07Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_168114_1 1618251.A0A0C5I2L8_9CIRC 1.26e-15 75.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_132509_2 395493.BegalDRAFT_1405 1.05e-38 136.0 COG0741@1|root,COG0741@2|Bacteria 2|Bacteria M lytic transglycosylase activity - - - ko:K03194 ko03070,map03070 M00333 - - ko00000,ko00001,ko00002,ko02044 - - - CHAP,SLT k59_229959_1 742740.HMPREF9474_02314 2.64e-25 102.0 2A0KC@1|root,30NQJ@2|Bacteria,1V3K4@1239|Firmicutes,24HYK@186801|Clostridia,222N6@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_241013_1 66875.JODY01000012_gene1450 1.45e-06 55.5 COG0673@1|root,COG0673@2|Bacteria,2GN2Z@201174|Actinobacteria 201174|Actinobacteria S oxidoreductase ydgJ - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C k59_21288_2 189425.PGRAT_19255 3.57e-16 77.4 COG3405@1|root,COG3405@2|Bacteria,1VBUA@1239|Firmicutes,4HMXV@91061|Bacilli,26Z1A@186822|Paenibacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - - - - - - - - - - - k59_314379_1 1121440.AUMA01000012_gene1362 3.23e-53 184.0 COG5323@1|root,COG5323@2|Bacteria,1R049@1224|Proteobacteria,42UYF@68525|delta/epsilon subdivisions,2WQN3@28221|Deltaproteobacteria,2M90K@213115|Desulfovibrionales 28221|Deltaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6 k59_59028_1 665942.HMPREF1022_03285 9.37e-13 76.6 28IA2@1|root,2Z8CQ@2|Bacteria,1PQM2@1224|Proteobacteria,42Y9U@68525|delta/epsilon subdivisions,2WTUC@28221|Deltaproteobacteria,2MARZ@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_107628_1 1469613.JT55_17455 6.19e-13 74.3 COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,2TTC7@28211|Alphaproteobacteria,3FDYQ@34008|Rhodovulum 28211|Alphaproteobacteria M Male sterility protein galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase k59_71434_2 105154.Q9MBU6_9VIRU 1.03e-180 527.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_241206_3 1385658.U5KPZ6_9VIRU 8.94e-223 632.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_241206_5 1385658.U5KNR1_9VIRU 4.38e-68 221.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_339166_1 1692247.A0A0K1RL30_9CIRC 1.7e-34 133.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_189521_1 935948.KE386495_gene2287 4.54e-12 74.3 COG0749@1|root,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,42FDS@68295|Thermoanaerobacterales 186801|Clostridia L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_pol_A,DNA_pol_A_exo1 k59_350987_1 1341181.FLJC2902T_09650 2.65e-13 82.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1HXMT@117743|Flavobacteriia,2NSJE@237|Flavobacterium 976|Bacteroidetes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_255159_1 1234888.K0A2J2_9VIRU 4.78e-34 130.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_190915_1 1968.JOEV01000056_gene4970 1.59e-07 60.5 COG3291@1|root,COG3291@2|Bacteria,2GJR2@201174|Actinobacteria 201174|Actinobacteria S Pkd domain containing protein - - - - - - - - - - - - CBM_4_9 k59_121330_2 1385658.U5KPZ6_9VIRU 1.06e-32 131.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_266777_2 1618237.A0A0C5IMG6_9CIRC 5.65e-131 382.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388300_2 1385658.U5KPZ6_9VIRU 1.51e-214 612.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_388300_6 1385658.U5KNR1_9VIRU 2.11e-48 167.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_190947_1 1609634.A0A0C5AFV4_9VIRU 5.68e-70 236.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_190949_1 547144.HydHO_0135 1.34e-39 149.0 COG0305@1|root,COG0305@2|Bacteria,2G3QP@200783|Aquificae 200783|Aquificae L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_266812_1 1154860.SAG0136_08135 5.98e-24 107.0 COG5283@1|root,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,4HEHJ@91061|Bacilli 91061|Bacilli D Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_279461_1 1283340.Q6WI94_BPKVM 0.000141 47.4 4QAUT@10239|Viruses,4QVIM@35237|dsDNA viruses no RNA stage,4QQ7X@28883|Caudovirales,4QIGV@10662|Myoviridae 10662|Myoviridae S DNA ligase (ATP) activity - - - - - - - - - - - - - k59_190960_1 1392540.P256_00728 2.93e-26 104.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,1SQ0T@1236|Gammaproteobacteria,3NSW6@468|Moraxellaceae 1236|Gammaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_279471_2 1121440.AUMA01000011_gene2403 3.91e-12 67.0 2E645@1|root,330T3@2|Bacteria,1NEGX@1224|Proteobacteria,43352@68525|delta/epsilon subdivisions,2X1NK@28221|Deltaproteobacteria,2MFDF@213115|Desulfovibrionales 28221|Deltaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_388306_2 1618248.A0A0C5IB82_9CIRC 1.55e-68 223.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_364521_2 1732201.A0A0N9N7I3_9CIRC 1.25e-32 124.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388395_1 1385658.U5KPZ6_9VIRU 1.53e-196 565.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_388395_3 1165094.RINTHH_3920 4.66e-61 204.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_98351_1 691965.D4P7I3_9CAUD 1.68e-284 825.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_98351_5 478749.BRYFOR_08565 7.75e-44 158.0 2A0KC@1|root,2ZGJK@2|Bacteria,1V2JS@1239|Firmicutes,24H6R@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_183061_3 1118054.CAGW01000106_gene3684 6.55e-23 103.0 COG1961@1|root,COG1961@2|Bacteria,1TPUG@1239|Firmicutes,4HB3H@91061|Bacilli,26VGC@186822|Paenibacillaceae 91061|Bacilli L Recombinase zinc beta ribbon domain - - - ko:K06400 - - - - ko00000 - - - Recombinase,Resolvase,Zn_ribbon_recom k59_304990_1 1141137.K4F7V7_9CAUD 3.76e-16 81.6 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNI0@10744|Podoviridae 10744|Podoviridae S viral capsid - GO:0005575,GO:0019012,GO:0019028,GO:0019030,GO:0039617,GO:0044423,GO:0046729 - - - - - - - - - - - k59_353738_4 1173029.JH980292_gene1144 1.8e-27 107.0 COG3773@1|root,COG3773@2|Bacteria 2|Bacteria M sporulation resulting in formation of a cellular spore cwlJ - 3.5.1.28 ko:K01449 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Hydrolase_2 k59_353738_5 1284775.HMPREF1640_07180 1.1e-13 69.7 2A8FF@1|root,30XHC@2|Bacteria,4PAYI@976|Bacteroidetes,2FY1R@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_195635_1 1144307.PMI04_03650 1.08e-53 187.0 COG4653@1|root,COG4653@2|Bacteria,1MWMB@1224|Proteobacteria,2TUJN@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_195635_2 1144307.PMI04_03649 2.29e-69 237.0 COG5511@1|root,COG5511@2|Bacteria,1MVN4@1224|Proteobacteria,2TSGI@28211|Alphaproteobacteria 28211|Alphaproteobacteria OU Phage portal protein lambda family - - - - - - - - - - - - Phage_portal_2 k59_378009_6 1408418.JNJH01000043_gene3127 5.27e-43 156.0 2FITE@1|root,34AIX@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_134752_1 1226994.AMZB01000137_gene5415 1.35e-12 67.4 2DNBC@1|root,32WJP@2|Bacteria,1N2F6@1224|Proteobacteria 1224|Proteobacteria S NinB protein - - - - - - - - - - - - NinB k59_134752_2 1484479.DI14_04910 1.44e-15 79.7 299WX@1|root,2ZWYS@2|Bacteria,1V4RB@1239|Firmicutes,4HRT6@91061|Bacilli 91061|Bacilli S ERF superfamily - - - - - - - - - - - - ERF k59_134752_3 1117958.PE143B_0130645 1.47e-34 130.0 2DIG9@1|root,3036R@2|Bacteria,1RBPA@1224|Proteobacteria,1T0EZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria L YqaJ-like viral recombinase domain - - - - - - - - - - - - YqaJ k59_159298_3 105154.Q9MBU6_9VIRU 1.44e-68 225.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_207952_3 691965.D4P7D6_9CAUD 1.65e-35 136.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_317314_1 1618248.A0A0C5IB82_9CIRC 3.25e-43 150.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_317314_2 1692242.A0A0K1RKZ2_9CIRC 3.61e-24 105.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_122897_5 2003327.CAPSD_BPCHP 2.19e-18 89.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_86259_6 1234888.K0A2J2_9VIRU 6.32e-140 417.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_245108_1 626887.J057_01640 2.52e-48 195.0 2DBPZ@1|root,2ZABJ@2|Bacteria,1R7CU@1224|Proteobacteria,1SKX7@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_160447_1 438753.AZC_3598 1.24e-86 279.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT52@1224|Proteobacteria,2TVNI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_2 k59_13770_1 1692252.A0A0K1RL35_9CIRC 1.12e-63 206.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_111646_6 1609634.A0A0C5ANA6_9VIRU 9.81e-16 80.9 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_26583_3 1379717.S5SY19_9CIRC 1.14e-38 144.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_354800_5 49964.Q94MS1_9CAUD 4.8e-90 276.0 4QB4H@10239|Viruses,4QYQI@35237|dsDNA viruses no RNA stage,4QUAR@28883|Caudovirales,4QNUV@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_366598_1 1472912.A0A023NGV8_9CAUD 2.83e-11 63.9 4QB0E@10239|Viruses,4QXJE@35237|dsDNA viruses no RNA stage,4QQU3@28883|Caudovirales 28883|Caudovirales S Pyrimidine dimer DNA glycosylase - GO:0000704,GO:0003674,GO:0003824,GO:0003906,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0140097 - - - - - - - - - - - k59_366598_4 1907.SGLAU_31260 3.71e-07 48.9 COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria 201174|Actinobacteria K Cold shock protein - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k59_111650_1 644107.SL1157_1635 4.06e-21 91.3 COG2404@1|root,COG2404@2|Bacteria,1PKY9@1224|Proteobacteria,2V2FR@28211|Alphaproteobacteria,4NDK2@97050|Ruegeria 28211|Alphaproteobacteria S hydrolase activity, acting on ester bonds - - - - - - - - - - - - - k59_306187_3 1173020.Cha6605_3816 1.6e-15 79.3 COG0338@1|root,COG0338@2|Bacteria,1G0BF@1117|Cyanobacteria 1117|Cyanobacteria L PFAM D12 class N6 adenine-specific DNA methyltransferase dam - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_209310_1 443152.MDG893_20559 1.51e-61 209.0 COG2911@1|root,COG2911@2|Bacteria,1QU6S@1224|Proteobacteria,1S7WY@1236|Gammaproteobacteria 1236|Gammaproteobacteria D tail tape measure protein - - - - - - - - - - - - SLT,Tape_meas_lam_C k59_196910_2 1042375.AFPL01000042_gene3813 3.32e-21 88.2 2AD08@1|root,312N7@2|Bacteria,1NDC4@1224|Proteobacteria,1SAPT@1236|Gammaproteobacteria,467W0@72275|Alteromonadaceae 1236|Gammaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_87415_1 186617.M9M8L2_9VIRU 0.000189 51.2 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_221516_1 1122991.BAIZ01000025_gene1859 8.71e-66 215.0 COG0270@1|root,COG0270@2|Bacteria,4NJPP@976|Bacteroidetes,2FKYT@200643|Bacteroidia 976|Bacteroidetes H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_209419_2 1392502.JNIO01000008_gene1496 1.24e-40 150.0 COG1061@1|root,COG1061@2|Bacteria,1TQ62@1239|Firmicutes,4H2T7@909932|Negativicutes 909932|Negativicutes L helicase superfamily c-terminal domain - - - - - - - - - - - - Helicase_C,Hom_end_hint,ResIII k59_75332_1 1234888.K0A2J2_9VIRU 1.72e-105 324.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_75332_3 145579.REP_BPPHM 1.75e-15 82.8 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_234275_14 1408428.JNJP01000030_gene963 3.22e-99 310.0 COG5323@1|root,COG5323@2|Bacteria,1R049@1224|Proteobacteria,42UYF@68525|delta/epsilon subdivisions,2WQN3@28221|Deltaproteobacteria,2M90K@213115|Desulfovibrionales 28221|Deltaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6 k59_39527_1 1445613.JALM01000017_gene5872 1.45e-07 59.7 COG3941@1|root,COG5412@1|root,COG3941@2|Bacteria,COG5412@2|Bacteria,2GNNQ@201174|Actinobacteria,4E86P@85010|Pseudonocardiales 201174|Actinobacteria M phage tail tape measure protein - - - - - - - - - - - - PhageMin_Tail,SLT k59_319627_4 882.DVU_1515 2.57e-36 135.0 COG0270@1|root,COG0270@2|Bacteria,1PPPB@1224|Proteobacteria,43A4E@68525|delta/epsilon subdivisions,2WUDB@28221|Deltaproteobacteria,2MB1N@213115|Desulfovibrionales 28221|Deltaproteobacteria L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_222462_5 1298858.AUEL01000029_gene39 9.79e-18 88.2 COG4725@1|root,COG4725@2|Bacteria,1R553@1224|Proteobacteria,2TRP6@28211|Alphaproteobacteria,43KW8@69277|Phyllobacteriaceae 28211|Alphaproteobacteria KT MT-A70 - - - - - - - - - - - - MT-A70,ParBc k59_222462_7 1123288.SOV_2c10440 1.24e-158 464.0 COG0553@1|root,COG0553@2|Bacteria,1TP2C@1239|Firmicutes,4H2V4@909932|Negativicutes 909932|Negativicutes KL DEAD-like helicases superfamily - - - - - - - - - - - - N6_N4_Mtase k59_222462_8 1120971.AUCA01000053_gene371 3.71e-135 391.0 COG0863@1|root,COG0863@2|Bacteria,1UZIN@1239|Firmicutes,4HU16@91061|Bacilli 91061|Bacilli L DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_222462_9 991905.SL003B_4054 8.66e-20 81.6 2E7GT@1|root,331ZH@2|Bacteria,1NAHD@1224|Proteobacteria,2UHC5@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_88538_3 1622190.A0A0E3T7W2_9CAUD 1.32e-154 476.0 4QAKZ@10239|Viruses,4QPYH@28883|Caudovirales,4QM57@10699|Siphoviridae 10699|Siphoviridae S intein-mediated protein splicing - - - - - - - - - - - - - k59_270510_1 2003327.CAPSD_BPCHP 1e-10 68.2 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_258606_1 1788438.A0A190WHE1_9CIRC 3.29e-28 119.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_3777_1 1217705.F900_00687 1.48e-11 72.8 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,1S0Q1@1236|Gammaproteobacteria,3NQUM@468|Moraxellaceae 1236|Gammaproteobacteria L DNA polymerase family A - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_39660_1 319236.JCM19294_758 1.5e-05 55.5 COG1345@1|root,COG1404@1|root,COG3897@1|root,COG1345@2|Bacteria,COG1404@2|Bacteria,COG3897@2|Bacteria,4PMFM@976|Bacteroidetes,1IJSB@117743|Flavobacteriia,3HJU7@363408|Nonlabens 976|Bacteroidetes N Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - Laminin_G_3 k59_64600_1 1234888.K0A2J2_9VIRU 2.39e-44 159.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_175629_1 716928.AJQT01000109_gene1217 3.04e-28 108.0 2FEUE@1|root,346TC@2|Bacteria,1MZPB@1224|Proteobacteria,2UC4Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_114307_2 622637.KE124774_gene435 1.48e-07 60.5 COG4974@1|root,COG4974@2|Bacteria,1MXZX@1224|Proteobacteria,2U0B6@28211|Alphaproteobacteria,36YPN@31993|Methylocystaceae 28211|Alphaproteobacteria L Phage integrase family - - - - - - - - - - - - Phage_int_SAM_1,Phage_integrase k59_41450_1 1618251.A0A0C5I2L8_9CIRC 1.26e-17 86.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_29919_1 1116375.VEJY3_21596 9.3e-06 55.5 COG4932@1|root,COG4932@2|Bacteria,1R944@1224|Proteobacteria,1S165@1236|Gammaproteobacteria,1Y09R@135623|Vibrionales 135623|Vibrionales M domain protein - - - - - - - - - - - - - k59_16429_1 1379725.S5SYG4_9CIRC 3.64e-24 106.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_151084_1 1234888.K0A2J2_9VIRU 4.28e-68 222.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_260127_2 446470.Snas_6269 1.46e-62 206.0 COG0863@1|root,COG0863@2|Bacteria,2I9DJ@201174|Actinobacteria 201174|Actinobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.113,2.1.1.72 ko:K00571,ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_66309_1 1169152.AXVD01000040_gene923 1.92e-28 116.0 2EFF2@1|root,3397X@2|Bacteria,2H8FI@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_199660_1 1609634.A0A0C5AFV4_9VIRU 7.73e-80 257.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_185772_1 1379711.S5SYC9_9CIRC 1.62e-15 80.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_212425_1 1173028.ANKO01000059_gene2943 1.07e-17 81.6 COG1404@1|root,COG1404@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family - - - ko:K01173 ko04210,map04210 - - - ko00000,ko00001,ko03029 - - - FAD_oxidored,FTP,PPC,Peptidase_M4,Peptidase_M4_C,Peptidase_S8,SLH,VCBS k59_102598_2 585.DR95_513 2.89e-27 112.0 28JXH@1|root,2Z9MZ@2|Bacteria,1MXNC@1224|Proteobacteria,1RNI6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S RecT family STY2074 - - - - - - - - - - - RecT k59_357426_1 1192868.CAIU01000008_gene927 4.28e-74 239.0 COG1783@1|root,COG1783@2|Bacteria,1PE12@1224|Proteobacteria,2V9EC@28211|Alphaproteobacteria,43QJZ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Mu-like prophage FluMu protein gp28 - - - - - - - - - - - - - k59_272545_1 1280681.AUJZ01000001_gene1053 9.1e-11 61.2 COG3695@1|root,COG3695@2|Bacteria,1VC8H@1239|Firmicutes 1239|Firmicutes L 6-O-methylguanine DNA methyltransferase, DNA binding domain ogt - - ko:K07443 - - - - ko00000 - - - DNA_binding_1 k59_272545_2 1121422.AUMW01000011_gene161 1.74e-18 84.7 COG2340@1|root,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,24I20@186801|Clostridia,26273@186807|Peptococcaceae 186801|Clostridia M PFAM Cysteine-rich secretory protein family - - - - - - - - - - - - CAP,LysM k59_333545_3 145579.REP_BPPHM 3.79e-07 56.6 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_286306_2 412597.AEPN01000003_gene3392 2.36e-07 53.1 28H5T@1|root,2Z7IB@2|Bacteria,1N7V9@1224|Proteobacteria,2TTZQ@28211|Alphaproteobacteria,2PUKQ@265|Paracoccus 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_286306_3 1121459.AQXE01000019_gene1890 2.4e-26 106.0 28HS3@1|root,2Z7ZE@2|Bacteria,1QH9A@1224|Proteobacteria,435JV@68525|delta/epsilon subdivisions,2WZY3@28221|Deltaproteobacteria,2M8GN@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_333548_1 1234888.K0A2J2_9VIRU 4.3e-51 177.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_114315_2 1385658.U5KNR1_9VIRU 8.3e-51 176.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_310600_7 1121440.AUMA01000002_gene2116 5.52e-11 68.9 2DUCB@1|root,33PX7@2|Bacteria 2|Bacteria S Methyltransferase domain - - - - - - - - - - - - Methyltransf_24 k59_17720_1 1379711.S5SYC9_9CIRC 5.06e-07 58.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_103969_1 1144310.PMI07_002360 7.39e-24 108.0 2DPZ1@1|root,3340X@2|Bacteria,1R2EE@1224|Proteobacteria,2TZIB@28211|Alphaproteobacteria,4BP2Q@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_92368_1 1234888.K0A2J2_9VIRU 2.09e-60 204.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_67716_1 1499689.CCNN01000007_gene1852 2.51e-05 52.0 COG5362@1|root,COG5362@2|Bacteria,1TSQB@1239|Firmicutes,24ACE@186801|Clostridia,36GBW@31979|Clostridiaceae 186801|Clostridia S TIGRFAM Phage - - - - - - - - - - - - - k59_6835_5 1572239.A0A0A0YP18_9CIRC 8.7e-11 69.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_335215_1 926692.AZYG01000059_gene80 7.62e-51 172.0 COG3723@1|root,COG3723@2|Bacteria,1V0QW@1239|Firmicutes,25DRE@186801|Clostridia 186801|Clostridia L RecT family - - - - - - - - - - - - RecT k59_164953_2 888049.HMPREF8578_0680 2.1e-59 193.0 COG0863@1|root,COG0863@2|Bacteria,1VU60@1239|Firmicutes 1239|Firmicutes L DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_347249_3 583345.Mmol_1800 0.000206 45.8 COG2197@1|root,COG2197@2|Bacteria,1RG6R@1224|Proteobacteria,2VRUT@28216|Betaproteobacteria,2KKJV@206350|Nitrosomonadales 206350|Nitrosomonadales K TIGRFAM transcriptional regulator EpsA - - - - - - - - - - - - GerE k59_383025_1 1348657.M622_03065 5.17e-42 149.0 COG4643@1|root,COG4643@2|Bacteria,1MW9E@1224|Proteobacteria,2VKFM@28216|Betaproteobacteria,2KVKJ@206389|Rhodocyclales 206389|Rhodocyclales S Zinc-binding domain of primase-helicase - - - ko:K06919 - - - - ko00000 - - - Prim_Zn_Ribbon,Toprim_3 k59_237398_1 469378.Ccur_02570 1.73e-07 49.7 29154@1|root,2ZNSE@2|Bacteria,2HCBY@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_347251_1 1385658.U5KPZ6_9VIRU 7.35e-70 231.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_237402_1 883158.HMPREF9140_01826 3.04e-13 68.9 COG1208@1|root,COG1208@2|Bacteria,4NMJ5@976|Bacteroidetes,2FNEE@200643|Bacteroidia 976|Bacteroidetes JM Nucleotidyl transferase hddC - - - - - - - - - - - NTP_transferase k59_237402_2 113395.AXAI01000011_gene6431 2.71e-27 113.0 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,2TRCN@28211|Alphaproteobacteria,3JTVF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - - - - - - - - - - CTP_transf_like,PfkB k59_324837_1 1692259.A0A0K1RL59_9CIRC 1.28e-28 115.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_166239_3 1219035.NT2_13_00580 9.8e-47 171.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_275615_2 488538.SAR116_0386 3.15e-07 52.4 COG1351@1|root,COG1351@2|Bacteria,1MWY8@1224|Proteobacteria,2TTER@28211|Alphaproteobacteria,4BRKK@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant thyX - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 k59_142084_1 1618247.A0A0C5IMK7_9CIRC 9.45e-09 60.8 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_44926_1 1121918.ARWE01000001_gene1797 8.44e-15 76.3 COG1404@1|root,COG1404@2|Bacteria,1QYWU@1224|Proteobacteria,42VXP@68525|delta/epsilon subdivisions,2X7PK@28221|Deltaproteobacteria 28221|Deltaproteobacteria O PFAM SMP-30 Gluconolaconase - - - - - - - - - - - - - k59_337051_1 1449351.RISW2_21990 2.75e-14 76.6 COG0740@1|root,COG0740@2|Bacteria,1MUQ9@1224|Proteobacteria,2U37W@28211|Alphaproteobacteria 28211|Alphaproteobacteria OU Belongs to the peptidase S14 family - - - - - - - - - - - - CLP_protease k59_337054_1 1618259.A0A0C5I2B5_9CIRC 2.39e-24 105.0 4QE84@10239|Viruses,4QUKR@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_227861_3 290400.Jann_2321 1.22e-08 59.7 COG3108@1|root,COG3772@1|root,COG3108@2|Bacteria,COG3772@2|Bacteria,1QYHH@1224|Proteobacteria,2UGWI@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_275814_2 145579.H_BPPHM 0.000719 47.4 4QCA6@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_349057_2 1540097.A0A0A0YRN0_9CAUD 2.92e-32 128.0 4QF3C@10239|Viruses,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_94479_1 1524467.IV04_20445 1.8e-27 103.0 2D7I9@1|root,32TP3@2|Bacteria,1N2ZM@1224|Proteobacteria,1S9DB@1236|Gammaproteobacteria,403TS@613|Serratia 1236|Gammaproteobacteria S Protein of unknown function (DUF1364) ybcO - - - - - - - - - - - DUF1364 k59_69801_3 572265.HDEF_1701 5.55e-35 125.0 2AD08@1|root,312N7@2|Bacteria,1NDC4@1224|Proteobacteria,1SAPT@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_361893_1 933262.AXAM01000071_gene2218 1.35e-22 97.1 28XPA@1|root,2ZJK5@2|Bacteria,1P9T2@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_374434_1 1121121.KB894297_gene4142 6.37e-13 67.0 2C2FS@1|root,3347I@2|Bacteria,1VFU8@1239|Firmicutes,4HWRD@91061|Bacilli,275TY@186822|Paenibacillaceae 91061|Bacilli S ASCH domain - - - - - - - - - - - - ASCH k59_291251_2 1609634.A0A0C5AFV4_9VIRU 1.01e-73 238.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_302694_2 349521.HCH_02886 1.38e-40 141.0 COG3023@1|root,COG3023@2|Bacteria,1N032@1224|Proteobacteria,1SFIP@1236|Gammaproteobacteria,1XPM6@135619|Oceanospirillales 135619|Oceanospirillales V N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2 k59_35242_2 1385658.U5KPZ6_9VIRU 2.05e-178 520.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_350807_1 272568.GDI3670 3.44e-26 112.0 COG0234@1|root,COG0234@2|Bacteria,1NJKP@1224|Proteobacteria,2UM25@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter - - - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - - k59_59070_2 291985.CCSI01000001_gene2604 6.22e-35 128.0 COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,2TQXM@28211|Alphaproteobacteria,2K0WQ@204457|Sphingomonadales 204457|Sphingomonadales L Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - RadC k59_204901_1 484019.THA_826 9.45e-40 154.0 COG0305@1|root,COG0305@2|Bacteria,2GC55@200918|Thermotogae 200918|Thermotogae L Participates in initiation and elongation during chromosome replication - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_119281_4 266809.PM03_15090 1.22e-94 289.0 COG3409@1|root,COG4322@1|root,COG3409@2|Bacteria,COG4322@2|Bacteria,1NCJ6@1224|Proteobacteria,2U1UB@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_1 k59_206233_3 1444310.JANV01000096_gene3227 1.52e-05 54.7 2EN4Y@1|root,32KKF@2|Bacteria,1UBN5@1239|Firmicutes,4IN2Q@91061|Bacilli,1ZMP2@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k59_169639_2 1234880.K0A2H8_9CIRC 9.52e-24 106.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_169639_4 1618238.A0A0C5I2G8_9CIRC 1.41e-36 137.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_266507_56 1120963.KB894494_gene3673 1.24e-18 89.7 COG0467@1|root,COG3598@1|root,COG4983@1|root,COG0467@2|Bacteria,COG3598@2|Bacteria,COG4983@2|Bacteria 2|Bacteria L Phage plasmid primase, P4 family domain protein - - - ko:K06919 - - - - ko00000 - - - AAA_11,AAA_12,AAA_25,DUF3320,DUF4011,Prim-Pol k59_266515_2 1618257.A0A0C5IBI9_9CIRC 4.17e-85 262.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_169901_2 151528.Q8W711_9CAUD 3.92e-51 184.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_190687_1 742733.HMPREF9469_05062 2.31e-122 363.0 COG0553@1|root,COG0553@2|Bacteria,1TS9W@1239|Firmicutes,24CGX@186801|Clostridia,222GT@1506553|Lachnoclostridium 186801|Clostridia KL Helicase conserved C-terminal domain - - - - - - - - - - - - - k59_363951_2 1298858.AUEL01000029_gene95 4.75e-53 194.0 COG1345@1|root,COG1345@2|Bacteria,1QZZ9@1224|Proteobacteria,2TZSX@28211|Alphaproteobacteria 28211|Alphaproteobacteria N Prophage tail length tape measure protein - - - - - - - - - - - - TMP_2 k59_266521_1 1114964.L485_00800 8.33e-45 151.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2U5BZ@28211|Alphaproteobacteria,2K464@204457|Sphingomonadales 204457|Sphingomonadales L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_376452_1 1609634.A0A0C5AFV4_9VIRU 7e-53 185.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_206489_2 1385658.U5KNR1_9VIRU 2.87e-21 93.2 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_242855_3 1165094.RINTHH_3920 4.65e-25 104.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_254991_1 1132441.KI519454_gene936 4.13e-08 62.0 COG4974@1|root,COG4974@2|Bacteria,2GN10@201174|Actinobacteria,1WAX3@1268|Micrococcaceae 201174|Actinobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_1,Phage_integrase k59_23064_2 1114964.L485_16325 4.33e-46 168.0 COG0270@1|root,COG0270@2|Bacteria 2|Bacteria L DNA (cytosine-5-)-methyltransferase activity ydiP - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_363969_3 1304878.AUGD01000002_gene1833 1.7e-18 86.3 2DZ82@1|root,32V6V@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Tube k59_388241_1 644524.C5IHQ5_9CAUD 4.12e-49 183.0 4QHMY@10239|Viruses,4QW88@35237|dsDNA viruses no RNA stage,4QSGS@28883|Caudovirales,4QNFN@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_376465_1 1121937.AUHJ01000007_gene1934 3.82e-31 115.0 2DICG@1|root,302RI@2|Bacteria,1PVSB@1224|Proteobacteria,1STCY@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_254997_2 1224746.B932_1151 0.000779 47.0 2E5T9@1|root,330HK@2|Bacteria,1N9RB@1224|Proteobacteria,2UHDB@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - Sulfotransfer_2 k59_254997_3 760192.Halhy_0673 3.66e-25 101.0 COG4122@1|root,COG4122@2|Bacteria 2|Bacteria E O-methyltransferase activity - - - - - - - - - - - - Glycos_transf_2,Methyltransf_24 k59_242858_2 485915.Dret_1613 1.48e-24 99.0 2DPI1@1|root,3325Q@2|Bacteria 2|Bacteria S DNA-packaging protein gp3 - - - - - - - - - - - - GP3_package k59_242858_3 1121921.KB898706_gene3039 4.03e-63 211.0 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,1RQFD@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage terminase, large subunit Z012_12305 - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_363971_1 1385658.U5KPZ6_9VIRU 1.11e-22 102.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_121064_3 1121271.AUCM01000031_gene2563 1.17e-53 179.0 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2UDUF@28211|Alphaproteobacteria 28211|Alphaproteobacteria G lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - PG_binding_1,Phage_lysozyme k59_242862_1 1054461.G0XNW8_9CAUD 2.21e-50 176.0 4QEFX@10239|Viruses,4QYYG@35237|dsDNA viruses no RNA stage,4QRRV@28883|Caudovirales,4QNTK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_169931_1 426355.Mrad2831_5695 8.18e-23 100.0 COG3170@1|root,COG3170@2|Bacteria,1R69E@1224|Proteobacteria,2U3B9@28211|Alphaproteobacteria 28211|Alphaproteobacteria NU Phage P22-like portal protein - - - - - - - - - - - - - k59_169931_2 1121441.AUCX01000001_gene2681 3.66e-10 61.6 COG5362@1|root,COG5362@2|Bacteria,1PYY9@1224|Proteobacteria,435M3@68525|delta/epsilon subdivisions,2WZZT@28221|Deltaproteobacteria,2M981@213115|Desulfovibrionales 28221|Deltaproteobacteria S TIGRFAM Phage - - - - - - - - - - - - - k59_364875_1 1234888.K0A2J2_9VIRU 2.28e-52 181.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_109807_1 97138.C820_00775 9e-16 81.6 COG3935@1|root,COG3935@2|Bacteria,1V69W@1239|Firmicutes,24IDX@186801|Clostridia,36JMY@31979|Clostridiaceae 186801|Clostridia L DnaD domain protein - - - - - - - - - - - - DnaB_2 k59_207152_2 1150626.PHAMO_340047 1.65e-18 87.8 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria,2JYGZ@204441|Rhodospirillales 204441|Rhodospirillales S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_207154_1 1121441.AUCX01000014_gene507 3.05e-19 93.6 COG5563@1|root,COG5563@2|Bacteria,1Q0JE@1224|Proteobacteria,430IH@68525|delta/epsilon subdivisions,2X0GF@28221|Deltaproteobacteria,2MD65@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_280051_1 1123058.KB894219_gene156 9.44e-21 89.4 COG2852@1|root,COG2852@2|Bacteria,4NX7B@976|Bacteroidetes 976|Bacteroidetes S Protein conserved in bacteria - - - - - - - - - - - - - k59_146275_10 61273.S3BW10 1.65e-05 53.9 COG0465@1|root,KOG0743@2759|Eukaryota,39U06@33154|Opisthokonta,3NX6C@4751|Fungi,3QMIC@4890|Ascomycota,214AG@147550|Sordariomycetes,3UPY0@5151|Ophiostomatales 4751|Fungi U BCS1_N - - - ko:K08900 - - - - ko00000,ko03029 - - - AAA,BCS1_N k59_219367_1 105154.Q9MBU6_9VIRU 8.13e-134 402.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_158539_1 1234888.K0A2J2_9VIRU 3.15e-77 248.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_109833_1 1380394.JADL01000006_gene5258 4.28e-59 196.0 28NGF@1|root,2ZBII@2|Bacteria,1R9KY@1224|Proteobacteria,2U1P7@28211|Alphaproteobacteria,2JXPF@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_267640_1 105154.Q9MBU6_9VIRU 1.25e-53 184.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_267640_2 10855.H_SPV4 2.58e-08 57.8 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_329183_5 314225.ELI_11110 3.81e-56 181.0 COG0739@1|root,COG0739@2|Bacteria 2|Bacteria M heme binding - - - - - - - - - - - - Cu_amine_oxidN1,Peptidase_M23 k59_329183_10 716928.AJQT01000025_gene4012 2.65e-10 73.6 COG3266@1|root,COG3266@2|Bacteria 2|Bacteria GM domain, Protein oapA - 2.7.7.7,3.1.26.12 ko:K02343,ko:K02451,ko:K06867,ko:K07268,ko:K08300 ko00230,ko00240,ko01100,ko03018,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03018,map03030,map03430,map03440 M00260,M00331,M00394 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko02044,ko03009,ko03019,ko03032,ko03400 9.B.42 - - Collagen,DNA_pol3_tau_5,OapA,OapA_N,T2SSB k59_341308_6 1609634.A0A0C5AFV4_9VIRU 1.6e-225 639.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_341308_7 1609634.A0A0C5ANA6_9VIRU 2.53e-22 96.7 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_256393_2 1788439.A0A190WHD0_9CIRC 2.11e-58 196.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_86234_1 1165094.RINTHH_3920 6.16e-83 258.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_86234_4 105154.Q9MBU6_9VIRU 3.18e-59 198.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_292923_5 1732201.A0A0N9N7I3_9CIRC 1.18e-09 62.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_62222_1 438753.AZC_0840 7.82e-70 240.0 COG3170@1|root,COG3170@2|Bacteria,1R69E@1224|Proteobacteria,2U3B9@28211|Alphaproteobacteria 28211|Alphaproteobacteria NU Phage P22-like portal protein - - - - - - - - - - - - - k59_25472_1 1238182.C882_1989 2.77e-50 181.0 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,2TVGJ@28211|Alphaproteobacteria,2JPR0@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_62228_2 1137269.AZWL01000042_gene1234 3.28e-06 50.8 COG0739@1|root,COG0741@1|root,COG0739@2|Bacteria,COG0741@2|Bacteria,2I8JC@201174|Actinobacteria 201174|Actinobacteria M Peptidase family M23 - - - - - - - - - - - - Peptidase_M23,SLT k59_256399_2 1692249.A0A0K1RLN8_9CIRC 9.79e-37 135.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_159266_2 1609634.A0A0C5AFT2_9VIRU 5.97e-38 144.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_159266_6 1385658.U5KPZ6_9VIRU 4.01e-109 332.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_98469_3 1054968.G0X516_9CAUD 3.65e-07 52.8 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QPEB@28883|Caudovirales,4QNC3@10744|Podoviridae 10744|Podoviridae S endonuclease activity - - - - - - - - - - - - - k59_244074_1 1028800.RG540_CH13740 7.09e-82 269.0 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,2TVEI@28211|Alphaproteobacteria,4BIH2@82115|Rhizobiaceae 28211|Alphaproteobacteria L DNA polymerase A domain - - - - - - - - - - - - DNA_pol_A k59_377983_1 317025.Tcr_0674 9.81e-10 58.5 COG3926@1|root,COG3926@2|Bacteria,1MVXW@1224|Proteobacteria,1RRB6@1236|Gammaproteobacteria,462PJ@72273|Thiotrichales 72273|Thiotrichales S Predicted Peptidoglycan domain - - - - - - - - - - - - Glyco_hydro_108,PG_binding_3 k59_377983_3 334413.FMG_1571 1.21e-14 74.7 COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia,22H7K@1570339|Peptoniphilaceae 186801|Clostridia F ComE operon protein 2 comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_377983_4 1117318.PRUB_18645 2.04e-13 76.3 COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria,2Q1W6@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA GO:0000287,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046385,GO:0046483,GO:0046872,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2827,iAPECO1_1312.APECO1_3678,iBWG_1329.BWG_2562,iE2348C_1286.E2348C_3096,iEC042_1314.EC042_3024,iEC55989_1330.EC55989_3103,iECABU_c1320.ECABU_c31240,iECDH10B_1368.ECDH10B_2997,iECDH1ME8569_1439.ECDH1ME8569_2734,iECED1_1282.ECED1_3283,iECH74115_1262.ECH74115_4093,iECIAI1_1343.ECIAI1_2935,iECIAI39_1322.ECIAI39_3246,iECNA114_1301.ECNA114_2885,iECO103_1326.ECO103_3386,iECO111_1330.ECO111_3555,iECO26_1355.ECO26_3899,iECOK1_1307.ECOK1_3231,iECP_1309.ECP_2840,iECS88_1305.ECS88_3122,iECSE_1348.ECSE_3084,iECSF_1327.ECSF_2642,iECSP_1301.ECSP_3779,iECUMN_1333.ECUMN_3154,iECW_1372.ECW_m3069,iECs_1301.ECs3684,iEKO11_1354.EKO11_0914,iETEC_1333.ETEC_3014,iEcDH1_1363.EcDH1_0864,iEcE24377_1341.EcE24377A_3147,iEcSMS35_1347.EcSMS35_2974,iG2583_1286.G2583_3481,iJO1366.b2827,iJR904.b2827,iLF82_1304.LF82_2267,iNRG857_1313.NRG857_13965,iSSON_1240.SSON_2984,iUMN146_1321.UM146_02290,iUMNK88_1353.UMNK88_3511,iUTI89_1310.UTI89_C3229,iWFL_1372.ECW_m3069,iY75_1357.Y75_RS14705,iYL1228.KPN_03236,iZ_1308.Z4144,ic_1306.c3422 Thymidylat_synt k59_26603_2 1385658.U5KNR1_9VIRU 2.12e-75 241.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_99525_1 1385658.U5KPZ6_9VIRU 1.23e-163 479.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_99525_6 1609634.A0A0C5ANA6_9VIRU 4.88e-09 62.4 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_99525_7 2003327.CAPSD_BPCHP 1.22e-40 148.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_172508_2 1618247.A0A0C5IMK7_9CIRC 1.79e-06 55.1 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_148022_2 1391027.T1YRW7_9VIRU 7.5e-11 65.5 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_99527_1 1537917.JU82_03700 1.28e-33 127.0 COG0553@1|root,COG0553@2|Bacteria 2|Bacteria L helicase activity - - - - - - - - - - - - Helicase_C,PLDc_2,ResIII,SNF2_N k59_99527_2 665950.HMPREF1025_01958 9.03e-27 105.0 2E0G5@1|root,32W28@2|Bacteria,1VAS0@1239|Firmicutes,24NYA@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_87421_3 1236542.BALM01000007_gene3443 5.88e-14 72.0 COG2852@1|root,COG2852@2|Bacteria,1N7EJ@1224|Proteobacteria,1SF5D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - DUF559 k59_354829_1 1453501.JELR01000001_gene2516 3.07e-53 192.0 COG4733@1|root,COG4926@1|root,COG4733@2|Bacteria,COG4926@2|Bacteria,1R77Q@1224|Proteobacteria,1S1WT@1236|Gammaproteobacteria,469QU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Fibronectin type 3 domain - - - - - - - - - - - - - k59_257647_1 745776.DGo_CA1889 2.97e-13 75.9 COG1783@1|root,COG1783@2|Bacteria 2|Bacteria S DNA packaging - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_6 k59_38670_2 1144310.PMI07_002360 4.2e-08 63.2 2DPZ1@1|root,3340X@2|Bacteria,1R2EE@1224|Proteobacteria,2TZIB@28211|Alphaproteobacteria,4BP2Q@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_209535_1 1197951.I6S6K3_9CAUD 2.09e-08 65.5 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_197893_2 716928.AJQT01000109_gene1217 1.41e-20 85.9 2FEUE@1|root,346TC@2|Bacteria,1MZPB@1224|Proteobacteria,2UC4Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_295176_1 1122201.AUAZ01000007_gene3692 1.89e-10 65.1 28H5T@1|root,2Z7IB@2|Bacteria,1N7V9@1224|Proteobacteria,1S23F@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_210604_1 1161931.J7FA60_9CAUD 1.62e-64 222.0 4QB9Y@10239|Viruses,4QWGZ@35237|dsDNA viruses no RNA stage,4QPTT@28883|Caudovirales,4QJD7@10662|Myoviridae 10662|Myoviridae S hydrolase activity - - - - - - - - - - - - - k59_76415_1 1096546.WYO_0193 1.21e-45 160.0 28JC4@1|root,2Z96S@2|Bacteria,1RI8W@1224|Proteobacteria 1224|Proteobacteria S P22 coat protein-protein 5 domain protein - - - - - - - - - - - - - k59_222680_2 1476888.X4YWQ6_9CAUD 5.38e-27 109.0 4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_39704_3 411464.DESPIG_00881 1.24e-11 75.5 COG5511@1|root,COG5511@2|Bacteria,1MVN4@1224|Proteobacteria,42VU9@68525|delta/epsilon subdivisions,2WRKB@28221|Deltaproteobacteria,2M93F@213115|Desulfovibrionales 28221|Deltaproteobacteria S phage portal protein, lambda - - - - - - - - - - - - Phage_portal_2 k59_367784_2 1547437.LL06_25630 3.95e-29 112.0 COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,43HCW@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_125436_1 243233.MCA2341 3.8e-12 64.3 COG1192@1|root,COG1192@2|Bacteria,1MWRE@1224|Proteobacteria,1RTVR@1236|Gammaproteobacteria,1XGRQ@135618|Methylococcales 135618|Methylococcales D Anion-transporting ATPase - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k59_125436_2 857087.Metme_1986 2.72e-14 67.4 2ER1H@1|root,33IM1@2|Bacteria,1NKBQ@1224|Proteobacteria,1SH23@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_210605_1 1500301.JQMF01000006_gene1760 1.92e-108 333.0 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,2TVEI@28211|Alphaproteobacteria,4BIH2@82115|Rhizobiaceae 28211|Alphaproteobacteria L DNA polymerase A domain - - - - - - - - - - - - DNA_pol_A k59_161761_1 1476876.JOJO01000002_gene6633 6.67e-58 206.0 2B5CX@1|root,31Y73@2|Bacteria,2H0BC@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_307539_2 145579.CAPSD_BPPHM 1.6e-47 169.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_258666_2 1385658.U5KPZ6_9VIRU 2.96e-206 590.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_258666_3 105154.Q9MBU3_9VIRU 3.37e-06 53.9 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_258666_6 145579.REP_BPPHM 6.31e-30 121.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_64668_3 1165094.RINTHH_3920 1.02e-41 154.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_235512_4 319795.Dgeo_0872 8.5e-59 200.0 COG0714@1|root,COG0714@2|Bacteria,1WKMC@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S AAA domain (dynein-related subfamily) - - - - - - - - - - - - AAA_5 k59_235512_7 1121451.DESAM_22654 1.39e-61 211.0 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,42QJ2@68525|delta/epsilon subdivisions,2WM78@28221|Deltaproteobacteria,2M8CT@213115|Desulfovibrionales 28221|Deltaproteobacteria S VWA-like domain (DUF2201) - - - - - - - - - - - - DUF2201,DUF2201_N k59_5055_2 537013.CLOSTMETH_01710 8.32e-15 72.0 2EF3G@1|root,338WJ@2|Bacteria,1VHUW@1239|Firmicutes,24R77@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_285718_1 1385658.U5KPZ6_9VIRU 8.09e-92 289.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_357031_1 1676184.A0A186YBN5_9CIRC 2.45e-32 123.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_357031_2 1506572.A0A097ZPG0_9CIRC 1.7e-25 105.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_308799_2 1123508.JH636464_gene276 2.25e-27 116.0 COG1061@1|root,COG1061@2|Bacteria,2J0ES@203682|Planctomycetes 203682|Planctomycetes L COGs COG1061 DNA or RNA helicase of superfamily II - - - ko:K19789 - - - - ko00000,ko03400 - - - Helicase_C,ResIII k59_53392_3 2003327.CAPSD_BPCHP 2.85e-33 141.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_175188_1 1121428.DESHY_40132___1 5.74e-05 50.1 COG0265@1|root,COG0265@2|Bacteria,1TRQS@1239|Firmicutes,24E3C@186801|Clostridia,260WW@186807|Peptococcaceae 186801|Clostridia O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - - - - - - - - - - Peptidase_S7,Trypsin k59_321135_1 1618247.A0A0C5IMK7_9CIRC 2.61e-07 57.4 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_212131_1 1380390.JIAT01000009_gene761 1.16e-10 70.1 COG3598@1|root,COG3598@2|Bacteria,2ISBM@201174|Actinobacteria 201174|Actinobacteria L AAA domain - - - - - - - - - - - - AAA_25,Prim-Pol k59_333240_1 358823.DF19_41745 1.42e-09 63.9 COG4626@1|root,COG4626@2|Bacteria,2GM6F@201174|Actinobacteria 201174|Actinobacteria L phage terminase - - - - - - - - - - - - Terminase_1 k59_333240_2 1274524.BSONL12_06123 3.48e-47 173.0 COG4695@1|root,COG4695@2|Bacteria,1TP8B@1239|Firmicutes,4HCI7@91061|Bacilli,1ZQG7@1386|Bacillus 91061|Bacilli S Phage portal protein - - - - - - - - - - - - Phage_portal k59_5195_1 220664.PFL_4674 1.13e-09 64.7 COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,1SN4D@1236|Gammaproteobacteria 1236|Gammaproteobacteria KL SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_322539_1 1120934.KB894408_gene4893 2.35e-17 88.6 2CHRY@1|root,30Z9E@2|Bacteria,2IJQT@201174|Actinobacteria,4E7WG@85010|Pseudonocardiales 201174|Actinobacteria - - - - - - - - - - - - - - - k59_128040_3 411460.RUMTOR_01350 0.000199 46.6 2EAAT@1|root,334F2@2|Bacteria,1VJJI@1239|Firmicutes,24TQU@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_128040_4 742740.HMPREF9474_02274 2.76e-19 85.5 2DHA9@1|root,32U8X@2|Bacteria,1VD44@1239|Firmicutes,24NC3@186801|Clostridia,222SC@1506553|Lachnoclostridium 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - - k59_334652_4 1609634.A0A0C5AFV4_9VIRU 1.28e-46 164.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_140095_1 1045855.DSC_11405 8.74e-51 178.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1RP8Z@1236|Gammaproteobacteria,1X6KE@135614|Xanthomonadales 135614|Xanthomonadales S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_200853_1 264462.Bd3182 2e-10 66.2 COG2911@1|root,COG2911@2|Bacteria,1QY25@1224|Proteobacteria,43C9F@68525|delta/epsilon subdivisions,2MUT5@213481|Bdellovibrionales,2X7JW@28221|Deltaproteobacteria 213481|Bdellovibrionales M cell wall surface anchor family protein - - - - - - - - - - - - Peptidase_S74 k59_140096_1 1429916.X566_00150 2.33e-29 114.0 COG0785@1|root,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,2TSAI@28211|Alphaproteobacteria,3K36A@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Cytochrome C biogenesis protein transmembrane region - - - ko:K06196 - - - - ko00000,ko02000 5.A.1.2 - - DsbD k59_6550_3 497965.Cyan7822_2805 1.8e-07 55.1 COG1403@1|root,COG3344@1|root,COG1403@2|Bacteria,COG3344@2|Bacteria,1G065@1117|Cyanobacteria,3KFZ7@43988|Cyanothece 1117|Cyanobacteria L PFAM RNA-directed DNA polymerase (Reverse transcriptase) - - 2.7.7.49 ko:K00986 - - - - ko00000,ko01000 - - - GIIM,HNH,RVT_1,RVT_N k59_176854_1 1618260.A0A0C5I2C5_9CIRC 1.23e-13 74.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_261059_1 1120960.ATXG01000008_gene161 1.45e-07 59.7 COG0210@1|root,COG0210@2|Bacteria,2GU9Z@201174|Actinobacteria,4FRI1@85023|Microbacteriaceae 201174|Actinobacteria L UvrD/REP helicase N-terminal domain - - - - - - - - - - - - AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2 k59_54960_3 558173.CDOO_01930 0.000205 49.3 COG4695@1|root,COG4695@2|Bacteria,2I9PX@201174|Actinobacteria,22M7Q@1653|Corynebacteriaceae 201174|Actinobacteria S Phage portal protein - - - - - - - - - - - - Phage_portal k59_346680_1 186617.M9M8L2_9VIRU 1.7e-39 150.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_273709_1 1244869.H261_03298 3.14e-11 63.2 COG3935@1|root,COG3935@2|Bacteria,1N8GP@1224|Proteobacteria,2UHJS@28211|Alphaproteobacteria,2JTTJ@204441|Rhodospirillales 204441|Rhodospirillales L DnaD domain protein - - - - - - - - - - - - - k59_164507_1 105154.Q9MBU6_9VIRU 1.94e-39 145.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_129566_1 1289135.A966_00355 3.05e-72 249.0 COG5283@1|root,COG5283@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - PhageMin_Tail k59_227154_1 1380894.S5TR92_9CIRC 6.17e-54 179.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_56463_1 1122951.ATUE01000005_gene1881 1.67e-24 110.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,3NK2H@468|Moraxellaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_227156_1 765912.Thimo_1748 3.24e-24 104.0 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,1RXX2@1236|Gammaproteobacteria,1WX24@135613|Chromatiales 135613|Chromatiales S VWA-like domain (DUF2201) - - - - - - - - - - - - DUF2201,DUF2201_N k59_324282_1 658172.CKC_03455 0.000217 49.3 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 658172.CKC_03455|- - - - - - - - - - - - - - - - k59_348328_1 691965.D4P7D3_9CAUD 7.31e-135 395.0 4QAYV@10239|Viruses,4QUZ7@35237|dsDNA viruses no RNA stage,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - k59_289189_2 1175306.GWL_37980 1.32e-17 82.8 COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,2VHMH@28216|Betaproteobacteria,472NV@75682|Oxalobacteraceae 28216|Betaproteobacteria M NeuB family neuB - 2.5.1.56,2.5.1.97 ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 - R01804,R04435,R09841 RC00159 ko00000,ko00001,ko01000 - - - NeuB,SAF k59_359831_4 1234888.K0A2J2_9VIRU 2.33e-98 308.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_80899_3 1528106.JRJE01000020_gene2295 6.65e-79 246.0 28HS3@1|root,2Z7ZE@2|Bacteria,1QH9A@1224|Proteobacteria,2TVB0@28211|Alphaproteobacteria,2JPPD@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_80899_5 472175.EL18_01356 2.59e-07 54.7 2DQJ1@1|root,3376F@2|Bacteria,1RKWB@1224|Proteobacteria,2UA4H@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - Beta_helix,Pectate_lyase_3 k59_238428_1 509191.AEDB02000020_gene3260 1.84e-48 172.0 COG4695@1|root,COG4695@2|Bacteria,1TP8B@1239|Firmicutes,2497C@186801|Clostridia,3WHWY@541000|Ruminococcaceae 186801|Clostridia S Phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_238428_2 339671.Asuc_1239 1.15e-47 161.0 COG3740@1|root,COG3740@2|Bacteria,1NHKT@1224|Proteobacteria,1S55B@1236|Gammaproteobacteria,1Y9VC@135625|Pasteurellales 135625|Pasteurellales S Caudovirus prohead serine protease - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78 k59_238428_3 1121289.JHVL01000007_gene2753 5.68e-50 181.0 COG4653@1|root,COG4653@2|Bacteria,1TS6A@1239|Firmicutes,24994@186801|Clostridia,36E6H@31979|Clostridiaceae 186801|Clostridia S Phage major capsid protein, HK97 family - - - - - - - - - - - - Phage_capsid k59_262615_1 1114964.L485_01010 1.04e-41 163.0 2DBPZ@1|root,2ZABJ@2|Bacteria,1R7CU@1224|Proteobacteria,2UEX4@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_336294_1 186617.M9M8L2_9VIRU 1.45e-146 431.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_34070_2 1082932.ATCR1_06741 1.72e-24 103.0 COG5323@1|root,COG5323@2|Bacteria,1R049@1224|Proteobacteria 1224|Proteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6 k59_337896_1 457412.RSAG_01145 2.11e-48 172.0 COG4383@1|root,COG4383@2|Bacteria,1TS7T@1239|Firmicutes,24CCB@186801|Clostridia,3WNCM@541000|Ruminococcaceae 186801|Clostridia S Mu-like prophage protein gp29 - - - - - - - - - - - - - k59_290552_1 268748.Q58N42_BPPRP 1.73e-17 92.4 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_9177_1 665956.HMPREF1032_00648 6.86e-17 76.3 2E0G5@1|root,32W28@2|Bacteria,1VAS0@1239|Firmicutes,24NYA@186801|Clostridia,3WNKT@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_34080_1 1385658.U5KPZ6_9VIRU 1.05e-36 138.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_276562_1 665950.HMPREF1025_01961 1.01e-137 404.0 COG0553@1|root,COG0553@2|Bacteria,1TS9W@1239|Firmicutes,24CGX@186801|Clostridia 186801|Clostridia KL Helicase conserved C-terminal domain - - - - - - - - - - - - - k59_70611_3 172088.AUGA01000033_gene4627 5.44e-05 48.5 2FEUE@1|root,346TC@2|Bacteria,1MZPB@1224|Proteobacteria,2UC4Q@28211|Alphaproteobacteria,3K04T@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_59621_1 1384066.JAGT01000001_gene965 2.31e-18 92.0 COG2887@1|root,COG2887@2|Bacteria,1TPIC@1239|Firmicutes,247TB@186801|Clostridia,3WHJH@541000|Ruminococcaceae 186801|Clostridia L Psort location Cytoplasmic, score - - - - - - - - - - - - DUF2800 k59_119997_3 1618238.A0A0C5IB41_9CIRC 2.94e-07 59.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_157469_1 1120945.ATUW01000020_gene6 3.34e-15 81.6 COG0791@1|root,COG0791@2|Bacteria,2I78U@201174|Actinobacteria,4D8B5@85005|Actinomycetales 201174|Actinobacteria M CHAP domain - - - - - - - - - - - - CHAP k59_351538_1 1692244.A0A0K1RLR5_9CIRC 3.17e-42 148.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_72200_1 1268240.ATFI01000008_gene2554 3.59e-11 62.8 2A084@1|root,30NBB@2|Bacteria,4PAX7@976|Bacteroidetes,2FXZ5@200643|Bacteroidia,4ATY3@815|Bacteroidaceae 976|Bacteroidetes - - - - - - - - - - - - - - - k59_72201_1 797303.Natpe_4088 5.63e-62 208.0 COG4983@1|root,arCOG01531@1|root,arCOG01531@2157|Archaea,arCOG06276@2157|Archaea,2XUG1@28890|Euryarchaeota,23SRM@183963|Halobacteria 183963|Halobacteria L Phage plasmid primase, P4 - - - ko:K06919 - - - - ko00000 - - - - k59_375371_2 279238.Saro_2694 2.59e-128 368.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2TU8N@28211|Alphaproteobacteria,2K409@204457|Sphingomonadales 204457|Sphingomonadales L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_339740_1 936140.AEOT01000014_gene1364 6.96e-15 88.6 COG3883@1|root,COG5283@1|root,COG5412@1|root,COG3883@2|Bacteria,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4IU4Q@91061|Bacilli,3FC2A@33958|Lactobacillaceae 91061|Bacilli S Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_189856_1 526225.Gobs_1726 6.97e-22 97.4 COG3409@1|root,COG3409@2|Bacteria 2|Bacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - CHAP,LysM,PG_binding_1,Phage_lysozyme k59_387188_1 1401065.HMPREF2130_11270 8.05e-06 52.0 COG5377@1|root,COG5377@2|Bacteria,1MWP8@1224|Proteobacteria,2VJH5@28216|Betaproteobacteria 28216|Betaproteobacteria L YqaJ-like viral recombinase domain - - - - - - - - - - - - YqaJ k59_388689_3 1788447.A0A190WHJ9_9CIRC 4.65e-83 255.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388691_2 1692249.A0A0K1RL40_9CIRC 8.98e-48 168.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_193114_1 1692244.A0A0K1RLR5_9CIRC 4.47e-29 118.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_193152_1 1123057.P872_18430 8.91e-05 52.4 29YBT@1|root,30K65@2|Bacteria,4NY8W@976|Bacteroidetes,47SZM@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_315992_1 279280.Q6J1S4_9CAUD 2.62e-49 170.0 4QG38@10239|Viruses,4QY33@35237|dsDNA viruses no RNA stage,4QQVI@28883|Caudovirales,4QNWM@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_315992_2 762984.HMPREF9445_00166 7.28e-13 70.1 2BVDA@1|root,32QTA@2|Bacteria,4NV3V@976|Bacteroidetes,2FTPW@200643|Bacteroidia,4ARH9@815|Bacteroidaceae 976|Bacteroidetes S DNA-packaging protein gp3 - - - - - - - - - - - - GP3_package k59_279546_1 1121374.KB891589_gene34 1.2e-13 70.5 COG2105@1|root,COG2105@2|Bacteria,1N94Q@1224|Proteobacteria,1SEE3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Gamma-glutamyl cyclotransferase, AIG2-like - - - - - - - - - - - - GGACT k59_230922_2 945713.IALB_0418 0.0001 44.7 COG1525@1|root,COG1525@2|Bacteria 2|Bacteria L nuclease lpxP - 3.1.31.1 ko:K01174 - - - - ko00000,ko01000 - - - SNase k59_48677_1 536232.CLM_2673 1.19e-20 95.9 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,36EDD@31979|Clostridiaceae 186801|Clostridia L DNA polymerase - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_121565_1 1234888.K0A2J2_9VIRU 2.43e-98 303.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_105_2 102125.Xen7305DRAFT_00036340 3.27e-16 81.3 2DKXV@1|root,30THP@2|Bacteria,1GQMH@1117|Cyanobacteria 1117|Cyanobacteria S Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_2 k59_182323_1 110365.A0A023B9A0 6.34e-09 61.6 2EWQP@1|root,2SYH6@2759|Eukaryota 2759|Eukaryota S RNA helicase - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_206629_3 2003327.CAPSD_BPCHP 2.84e-28 126.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_97549_2 1283078.M1IDT1_9CAUD 8.53e-14 68.9 4QAV0@10239|Viruses,4QY41@35237|dsDNA viruses no RNA stage,4QSR9@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_73297_4 287986.DV20_29915 1.35e-37 132.0 arCOG05626@1|root,30CNA@2|Bacteria,2I38B@201174|Actinobacteria,4EDYI@85010|Pseudonocardiales 201174|Actinobacteria - - - - - - - - - - - - - - - k59_85473_3 1609634.A0A0C5AFV4_9VIRU 3.99e-144 428.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_340478_2 608538.HTH_0544 7.24e-09 67.4 COG3064@1|root,COG3064@2|Bacteria 2|Bacteria M translation initiation factor activity - - - - - - - - - - - - PorP_SprF,TPR_16 k59_328506_1 1692250.A0A0K1RLR1_9CIRC 1.92e-07 53.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_109729_2 411460.RUMTOR_01326 1.08e-33 119.0 2EN82@1|root,33FVV@2|Bacteria,1VKRH@1239|Firmicutes,24V2G@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_109729_7 1120947.ATUX01000001_gene2001 9.6e-06 54.3 COG5280@1|root,COG5412@1|root,COG5280@2|Bacteria,COG5412@2|Bacteria,2H75F@201174|Actinobacteria,4D48B@85005|Actinomycetales 201174|Actinobacteria S tape measure - - - - - - - - - - - - - k59_24719_4 1234888.K0A2J2_9VIRU 4.78e-158 464.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_121875_2 105154.Q9MBU6_9VIRU 2.82e-195 564.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_364822_8 243265.plu0543 1.37e-09 67.4 COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria 1236|Gammaproteobacteria D recombinase XerD - - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_int_SAM_4,Phage_int_SAM_5,Phage_integrase k59_341022_1 225937.HP15_1949 4.78e-05 50.8 2DZHM@1|root,32VAY@2|Bacteria,1N0DC@1224|Proteobacteria,1SP9I@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_25163_1 1609634.A0A0C5ANA6_9VIRU 1.09e-13 73.9 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_292536_1 1264737.K9S139_9CAUD 2.47e-08 54.3 4QE7X@10239|Viruses,4QVF0@35237|dsDNA viruses no RNA stage,4QPUM@28883|Caudovirales,4QP17@10744|Podoviridae 10744|Podoviridae S Cytidine and deoxycytidylate deaminase zinc-binding region - - - - - - - - - - - - - k59_292536_8 1235661.K0IK58_9CAUD 4.77e-65 209.0 4QNC3@10744|Podoviridae 10744|Podoviridae S endonuclease activity - - - - - - - - - - - - - k59_292536_9 94624.Bpet1003 1.01e-35 127.0 COG3772@1|root,COG3772@2|Bacteria,1N0ZQ@1224|Proteobacteria,2VVDM@28216|Betaproteobacteria 28216|Betaproteobacteria S lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_280667_1 145579.CAPSD_BPPHM 7.63e-86 270.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_231732_2 411470.RUMGNA_02228 1.29e-18 98.2 COG3941@1|root,COG3941@2|Bacteria,1UK7D@1239|Firmicutes 1239|Firmicutes S tape measure - - - - - - - - - - - - - k59_243785_2 1166018.FAES_3935 9.48e-76 253.0 COG1783@1|root,COG5410@1|root,COG1783@2|Bacteria,COG5410@2|Bacteria,4NN30@976|Bacteroidetes,47YRR@768503|Cytophagia 976|Bacteroidetes S Phage terminase large subunit - - - - - - - - - - - - Terminase_6 k59_207597_4 1788439.A0A190WHD0_9CIRC 1.35e-18 92.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_98084_1 654929.REP_PCV1C 3.41e-24 103.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_915_2 376686.Fjoh_3546 1.1e-80 247.0 COG0270@1|root,COG0270@2|Bacteria,4P351@976|Bacteroidetes,1I9UJ@117743|Flavobacteriia,2NZ0G@237|Flavobacterium 976|Bacteroidetes L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_159977_4 1618247.A0A0C5I2K0_9CIRC 6.85e-17 82.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_123600_1 1476391.X5KCE1_9CAUD 3.46e-42 157.0 4QF3C@10239|Viruses,4QWIA@35237|dsDNA viruses no RNA stage,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_38213_1 1122604.JONR01000038_gene4296 4.01e-12 68.6 COG4227@1|root,COG4227@2|Bacteria,1MU8I@1224|Proteobacteria,1RNU7@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Antirestriction protein traC - - - - - - - - - - - DUF1738,Toprim_4 k59_305798_1 525257.HMPREF0204_11850 0.000922 49.7 2DPUU@1|root,333GA@2|Bacteria,4NUU7@976|Bacteroidetes,1ICM8@117743|Flavobacteriia,3ZRP6@59732|Chryseobacterium 976|Bacteroidetes S to other proteins from the same organism - - - - - - - - - - - - - k59_378495_3 1122221.JHVI01000015_gene1749 6.66e-09 57.4 COG4712@1|root,COG4712@2|Bacteria,1WIU2@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Rad52 22 double-strand break repair protein - - - - - - - - - - - - Rad52_Rad22 k59_183509_1 272568.GDI3673 4.92e-66 213.0 2DVPY@1|root,33WQ8@2|Bacteria,1N9VQ@1224|Proteobacteria,2UIC5@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_50534_2 714943.Mucpa_3747 9.72e-08 60.5 COG4733@1|root,COG4733@2|Bacteria,4NTXR@976|Bacteroidetes,1IZ2D@117747|Sphingobacteriia 976|Bacteroidetes S Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - CHU_C,Laminin_G_3 k59_232696_2 424949.U5N0F2_9CAUD 8.06e-20 89.0 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QKM7@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k59_159987_1 1527519.A0A076G6B5_9CAUD 0.00027 44.7 4QAVB@10239|Viruses,4QPIJ@28883|Caudovirales,4QI48@10662|Myoviridae 10662|Myoviridae S defense response to bacterium - - - - - - - - - - - - - k59_342061_2 1433126.BN938_0515 4.23e-13 70.9 COG5283@1|root,COG5283@2|Bacteria,4NIZH@976|Bacteroidetes 976|Bacteroidetes D domain protein - - - - - - - - - - - - PhageMin_Tail k59_196333_1 1283340.Q6WHK5_BPKVM 3.23e-19 95.5 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QI82@10662|Myoviridae 10662|Myoviridae S virus tail, fiber - - - - - - - - - - - - - k59_257197_1 1385658.U5KPZ6_9VIRU 1.25e-85 272.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_367106_1 744980.TRICHSKD4_2401 2.01e-51 178.0 COG0863@1|root,COG0863@2|Bacteria,1MY4G@1224|Proteobacteria,2U1X0@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_306834_2 1089547.KB913013_gene1705 3.93e-10 68.9 COG1361@1|root,COG1572@1|root,COG1361@2|Bacteria,COG1572@2|Bacteria,4NHBJ@976|Bacteroidetes,47N5U@768503|Cytophagia 976|Bacteroidetes M Domain of unknown function DUF11 - - - - - - - - - - - - DUF11,SASA k59_331360_1 105154.Q9MBU3_9VIRU 0.000756 44.3 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_331360_2 913970.F8RW82_9VIRU 2.19e-70 243.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_148541_1 1385658.U5KNR1_9VIRU 8.86e-42 150.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_283340_1 314275.MADE_000001022525 6.56e-31 125.0 COG3378@1|root,COG3378@2|Bacteria,1QVIS@1224|Proteobacteria,1S02S@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Psort location Cytoplasmic, score - - - ko:K06919 - - - - ko00000 - - - Prim-Pol,Toprim_3,Toprim_4 k59_355448_6 1304866.K413DRAFT_1261 1.81e-06 57.4 28HEE@1|root,2Z7QU@2|Bacteria,1TVQR@1239|Firmicutes,248QB@186801|Clostridia,36HCK@31979|Clostridiaceae 186801|Clostridia S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_355448_7 485916.Dtox_3913 3.84e-50 173.0 2BCCI@1|root,325XX@2|Bacteria,1URXQ@1239|Firmicutes,259VG@186801|Clostridia,263Q9@186807|Peptococcaceae 186801|Clostridia S Putative amidoligase enzyme - - - - - - - - - - - - Amidoligase_2 k59_88168_2 1430440.MGMSRv2_3490 4.4e-16 77.0 COG2227@1|root,COG2227@2|Bacteria,1QYVF@1224|Proteobacteria,2TZ70@28211|Alphaproteobacteria 28211|Alphaproteobacteria H 3-demethylubiquinone-9 3-O-methyltransferase activity - - - - - - - - - - - - - k59_112303_2 742918.D4N3P2_9CIRC 6.39e-27 115.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_367156_1 1165094.RINTHH_3920 2.64e-51 176.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_367156_3 1609634.A0A0C5AFV4_9VIRU 2.61e-172 504.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_367156_4 1385658.U5KQQ9_9VIRU 0.000517 47.4 4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_197493_1 105154.Q9MBU6_9VIRU 1.38e-170 496.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_184280_1 1096546.WYO_0201 4.47e-47 170.0 28P6A@1|root,2ZC10@2|Bacteria,1RBZE@1224|Proteobacteria,2UQEG@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_367161_1 948071.S4S2L2_9CAUD 1.47e-05 53.9 4QHQ5@10239|Viruses,4QR7K@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_379672_2 1121100.JCM6294_2214 1.49e-09 64.3 COG0270@1|root,COG0270@2|Bacteria,4NG9A@976|Bacteroidetes,2FNPZ@200643|Bacteroidia,4AN9J@815|Bacteroidaceae 976|Bacteroidetes H C-5 cytosine-specific DNA methylase dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase,Eco57I k59_381087_1 1234881.K0A1K7_9CIRC 7.7e-23 97.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_381087_2 1788454.A0A190WHE4_9CIRC 1.03e-34 128.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_368585_1 1536592.A0A088F776_9VIRU 1.7e-25 102.0 4QF7M@10239|Viruses 10239|Viruses S AAA domain - - - - - - - - - - - - - k59_77232_1 1033743.CAES01000104_gene3490 1.54e-33 137.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,4HEHJ@91061|Bacilli 91061|Bacilli D Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_174744_1 1089552.KI911559_gene3374 5.44e-47 162.0 28HS3@1|root,2Z7ZE@2|Bacteria,1QH9A@1224|Proteobacteria,2TVB0@28211|Alphaproteobacteria,2JPPD@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_308325_2 926560.KE387023_gene2268 2.96e-13 71.6 COG4712@1|root,COG4712@2|Bacteria,1WIU2@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Rad52 22 double-strand break repair protein ddrA GO:0001101,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009269,GO:0009314,GO:0009414,GO:0009415,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010212,GO:0010332,GO:0031668,GO:0033554,GO:0034641,GO:0042221,GO:0042631,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070887,GO:0071214,GO:0071229,GO:0071462,GO:0071465,GO:0071478,GO:0071479,GO:0071480,GO:0071496,GO:0071704,GO:0090304,GO:0104004,GO:1901360,GO:1901700,GO:1901701 - - - - - - - - - - Rad52_Rad22 k59_65401_2 439375.Oant_1512 2.28e-11 60.5 2BZTS@1|root,33131@2|Bacteria,1NBBP@1224|Proteobacteria,2UIZA@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_368587_1 375286.mma_2206 3.64e-20 91.7 COG5323@1|root,COG5323@2|Bacteria 2|Bacteria M Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6 k59_40535_1 411154.GFO_2450 4.37e-45 166.0 COG5362@1|root,COG5362@2|Bacteria,4PMSS@976|Bacteroidetes,1IJZ1@117743|Flavobacteriia 976|Bacteroidetes S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_150181_1 406818.XBJ1_2043 1.22e-23 99.8 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1SMCU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_198940_2 1470591.BW41_02766 6.33e-06 50.1 COG1609@1|root,COG1609@2|Bacteria,1NWPH@1224|Proteobacteria,2US0H@28211|Alphaproteobacteria,2K17J@204457|Sphingomonadales 204457|Sphingomonadales K Transcriptional regulator - - - - - - - - - - - - HTH_36 k59_15820_3 69328.PVLB_27102 6.57e-17 76.6 2BW73@1|root,2ZHHX@2|Bacteria,1P6PK@1224|Proteobacteria,1SVI5@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_223637_1 1618248.A0A0C5IB82_9CIRC 3.35e-26 106.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_138095_4 312309.VF_2017 2.81e-22 93.2 2CPEB@1|root,32SIW@2|Bacteria,1MZE0@1224|Proteobacteria,1SARU@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_185326_1 156889.Mmc1_1720 1.77e-20 100.0 28QU5@1|root,2ZD9H@2|Bacteria,1RAU8@1224|Proteobacteria,2UAGW@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_53182_2 40373.F991_00517 3.26e-36 124.0 2FB2D@1|root,34392@2|Bacteria,1N749@1224|Proteobacteria,1SSCS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_260405_1 392499.Swit_4451 3.57e-07 57.0 2ENQ2@1|root,33GBD@2|Bacteria,1NNPU@1224|Proteobacteria,2UN0X@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_103042_1 478749.BRYFOR_08513 1.46e-36 143.0 COG3409@1|root,COG3409@2|Bacteria 2|Bacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - Amidase_2,LysM,PG_binding_1 k59_114772_3 504832.OCAR_6140 1.59e-05 52.4 28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TURR@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_54399_1 2003327.CAPSD_BPCHP 3.25e-44 161.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_139477_2 1091052.I0J2W0_9CAUD 2.65e-18 84.7 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QHV3@10662|Myoviridae 10662|Myoviridae S lytic transglycosylase activity - - - - - - - - - - - - - k59_309781_1 1123072.AUDH01000029_gene1059 2.91e-15 87.0 COG4677@1|root,COG5434@1|root,COG4677@2|Bacteria,COG5434@2|Bacteria,1R7M4@1224|Proteobacteria,2U4CX@28211|Alphaproteobacteria,2JZM9@204441|Rhodospirillales 204441|Rhodospirillales M Pectate lyase superfamily protein - - - - - - - - - - - - Pectate_lyase_3 k59_297721_1 1676184.A0A186YBN5_9CIRC 2.31e-29 119.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_236462_1 1504822.CCNO01000015_gene594 1.58e-36 140.0 COG0553@1|root,COG0863@1|root,COG0553@2|Bacteria,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_186167_1 1224164.B843_03600 1.96e-29 125.0 COG0749@1|root,COG0749@2|Bacteria,2IG0A@201174|Actinobacteria,22MKV@1653|Corynebacteriaceae 201174|Actinobacteria L DNA polymerase I - 3'-5' exonuclease and polymerase domains - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_163955_2 765698.Mesci_3819 1.95e-112 332.0 28NGF@1|root,2ZBII@2|Bacteria,1R9KY@1224|Proteobacteria,2U1P7@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_54401_1 1305735.JAFT01000005_gene3871 1.01e-46 167.0 2CYA9@1|root,32T3V@2|Bacteria,1RGRN@1224|Proteobacteria,2U90D@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_54402_1 1297863.APJF01000020_gene2704 1.14e-19 95.9 28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TURR@28211|Alphaproteobacteria,3JUCC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_42176_1 117187.FVEG_09963T0 7.09e-17 85.5 2ENS4@1|root,2SS48@2759|Eukaryota,3ANK0@33154|Opisthokonta,3PGJB@4751|Fungi,3R0MA@4890|Ascomycota,218RZ@147550|Sordariomycetes 4751|Fungi S FAD dependent oxidoreductase - - - - - - - - - - - - NAD_binding_8 k59_42176_2 1265313.HRUBRA_02307 8.78e-12 66.2 COG0500@1|root,COG0500@2|Bacteria,1N2EQ@1224|Proteobacteria 1224|Proteobacteria Q methyltransferase - - - - - - - - - - - - - k59_369956_1 1229485.AMYV01000023_gene3046 2.82e-05 53.9 COG4228@1|root,COG4228@2|Bacteria,1R4HU@1224|Proteobacteria,1RPRY@1236|Gammaproteobacteria 1236|Gammaproteobacteria S DNA circulation protein - - - - - - - - - - - - DNA_circ_N k59_103225_4 497964.CfE428DRAFT_4747 1.72e-07 55.5 COG1974@1|root,COG1974@2|Bacteria,46SU8@74201|Verrucomicrobia 74201|Verrucomicrobia K Represses a number of genes involved in the response to DNA damage (SOS response) - - 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 k59_163965_2 322855.Q52PS3_9CAUD 3.82e-45 156.0 4QAUS@10239|Viruses,4QURX@35237|dsDNA viruses no RNA stage,4QQ2S@28883|Caudovirales 28883|Caudovirales S flavin adenine dinucleotide binding - - - - - - - - - - - - - k59_31800_1 215158.Q858G3_BPE15 8.68e-22 102.0 4QC24@10239|Viruses,4QZPR@35237|dsDNA viruses no RNA stage,4QRZK@28883|Caudovirales,4QP0N@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_201645_1 630626.EBL_c21830 1.04e-57 199.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,1RY0J@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_153345_1 1231241.Mc24_08964 9.17e-24 99.4 COG1573@1|root,COG1573@2|Bacteria,2GCA2@200918|Thermotogae 200918|Thermotogae L Uracil-DNA glycosylase - GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_18155_2 1168281.I3PUY1_9CAUD 4.93e-07 51.2 4QG00@10239|Viruses,4QZDS@35237|dsDNA viruses no RNA stage,4QTM4@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_140912_3 1217710.F969_02563 6.69e-22 95.1 COG5377@1|root,COG5377@2|Bacteria,1MWP8@1224|Proteobacteria,1RN9Q@1236|Gammaproteobacteria,3NIHJ@468|Moraxellaceae 1236|Gammaproteobacteria L YqaJ-like viral recombinase domain - - - - - - - - - - - - YqaJ k59_371351_1 105154.Q9MBU6_9VIRU 1.25e-37 142.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_165238_3 1692259.A0A0K1RL59_9CIRC 1.57e-38 147.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_104379_1 1210884.HG799467_gene13130 1.98e-70 222.0 COG0863@1|root,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_250164_1 105154.Q9MBU0_9VIRU 2.7e-18 84.7 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_347549_1 1788443.A0A190WHB4_9CIRC 1.37e-22 99.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_237941_1 1432056.X781_8090 2.85e-26 110.0 COG4653@1|root,COG4653@2|Bacteria,1MYMH@1224|Proteobacteria,1RR5E@1236|Gammaproteobacteria,1Y809@135625|Pasteurellales 135625|Pasteurellales S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_116453_2 1123237.Salmuc_02475 6.71e-13 77.4 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2TV2W@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG4733 Phage-related protein, tail component - - - - - - - - - - - - Phage-tail_3 k59_45141_2 1692249.A0A0K1RL40_9CIRC 2.04e-69 223.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_130746_1 1127515.H9C0H6_9CAUD 7.79e-06 53.9 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QI9F@10662|Myoviridae 10662|Myoviridae S Type III restriction enzyme, res subunit - - - - - - - - - - - - - k59_360540_1 938293.CAJU020000016_gene1776 2.38e-07 53.1 COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia,22GEW@1570339|Peptoniphilaceae 186801|Clostridia L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 k59_82037_3 1692248.A0A0K1RLN2_9CIRC 5.28e-90 277.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_373139_2 1379712.S5TMV9_9CIRC 8.44e-30 125.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_8889_2 1249975.JQLP01000001_gene3218 2.02e-17 84.0 COG1533@1|root,COG1533@2|Bacteria,4P7G9@976|Bacteroidetes 976|Bacteroidetes L DNA photolyase activity - - - - - - - - - - - - - k59_33693_1 7029.ACYPI080496-PA 5.3e-07 55.1 KOG1565@1|root,KOG1565@2759|Eukaryota,38CRR@33154|Opisthokonta,3B9IY@33208|Metazoa,3CT1E@33213|Bilateria,41VHF@6656|Arthropoda,3SINR@50557|Insecta,3ED0D@33342|Paraneoptera 33208|Metazoa O Matrixin MMP15 GO:0000003,GO:0000139,GO:0001501,GO:0001503,GO:0001525,GO:0001541,GO:0001558,GO:0001568,GO:0001655,GO:0001666,GO:0001704,GO:0001706,GO:0001763,GO:0001775,GO:0001822,GO:0001935,GO:0001944,GO:0001952,GO:0001953,GO:0001958,GO:0002009,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002682,GO:0002684,GO:0002685,GO:0002687,GO:0002694,GO:0002696,GO:0003006,GO:0003008,GO:0003674,GO:0003824,GO:0004175,GO:0004177,GO:0004222,GO:0004252,GO:0005102,GO:0005178,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005768,GO:0005794,GO:0005796,GO:0005802,GO:0005829,GO:0005856,GO:0005886,GO:0005887,GO:0006464,GO:0006508,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0006979,GO:0007155,GO:0007162,GO:0007275,GO:0007369,GO:0007399,GO:0007492,GO:0007548,GO:0007600,GO:0007610,GO:0007631,GO:0008047,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008236,GO:0008237,GO:0008238,GO:0008270,GO:0008283,GO:0008347,GO:0008406,GO:0008584,GO:0008585,GO:0008593,GO:0009056,GO:0009266,GO:0009581,GO:0009582,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009893,GO:0009966,GO:0009968,GO:0009986,GO:0009987,GO:0010001,GO:0010033,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0010646,GO:0010648,GO:0010810,GO:0010812,GO:0010830,GO:0010831,GO:0010952,GO:0010954,GO:0012505,GO:0012506,GO:0014070,GO:0016020,GO:0016021,GO:0016043,GO:0016048,GO:0016192,GO:0016477,GO:0016485,GO:0016504,GO:0016787,GO:0017171,GO:0019222,GO:0019233,GO:0019538,GO:0019827,GO:0022008,GO:0022411,GO:0022414,GO:0022610,GO:0022617,GO:0023051,GO:0023057,GO:0030141,GO:0030154,GO:0030155,GO:0030162,GO:0030198,GO:0030234,GO:0030307,GO:0030323,GO:0030324,GO:0030334,GO:0030335,GO:0030574,GO:0030659,GO:0030667,GO:0031012,GO:0031090,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031410,GO:0031638,GO:0031974,GO:0031982,GO:0031984,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032588,GO:0032879,GO:0032940,GO:0032963,GO:0035239,GO:0035295,GO:0035579,GO:0035987,GO:0035988,GO:0036075,GO:0036211,GO:0036230,GO:0036293,GO:0040008,GO:0040011,GO:0040012,GO:0040017,GO:0042063,GO:0042119,GO:0042221,GO:0042470,GO:0042581,GO:0042756,GO:0043009,GO:0043062,GO:0043085,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043299,GO:0043312,GO:0043412,GO:0043615,GO:0043627,GO:0044087,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044331,GO:0044352,GO:0044354,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044877,GO:0045055,GO:0045111,GO:0045137,GO:0045296,GO:0045321,GO:0045577,GO:0045579,GO:0045595,GO:0045597,GO:0045619,GO:0045621,GO:0045746,GO:0045862,GO:0045927,GO:0046545,GO:0046546,GO:0046660,GO:0046661,GO:0046872,GO:0046903,GO:0046914,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048562,GO:0048568,GO:0048583,GO:0048585,GO:0048598,GO:0048608,GO:0048646,GO:0048701,GO:0048704,GO:0048705,GO:0048706,GO:0048729,GO:0048731,GO:0048754,GO:0048770,GO:0048771,GO:0048856,GO:0048869,GO:0048870,GO:0050673,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050839,GO:0050864,GO:0050865,GO:0050867,GO:0050871,GO:0050877,GO:0050896,GO:0050906,GO:0050951,GO:0050961,GO:0050965,GO:0051094,GO:0051128,GO:0051129,GO:0051147,GO:0051149,GO:0051153,GO:0051155,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051249,GO:0051251,GO:0051270,GO:0051272,GO:0051336,GO:0051345,GO:0051604,GO:0051606,GO:0051674,GO:0051893,GO:0051895,GO:0052547,GO:0060021,GO:0060022,GO:0060255,GO:0060322,GO:0060348,GO:0060349,GO:0060350,GO:0060429,GO:0060541,GO:0060562,GO:0061134,GO:0061138,GO:0061458,GO:0062009,GO:0065007,GO:0065009,GO:0070006,GO:0070011,GO:0070013,GO:0070482,GO:0070613,GO:0071704,GO:0071840,GO:0071944,GO:0072001,GO:0072358,GO:0072359,GO:0080090,GO:0090109,GO:0097094,GO:0097150,GO:0097708,GO:0098588,GO:0098609,GO:0098727,GO:0098742,GO:0098772,GO:0098791,GO:0098805,GO:0099503,GO:0140096,GO:1901564,GO:1901888,GO:1901889,GO:1902105,GO:1902107,GO:1903317,GO:1903319,GO:1903391,GO:1903392,GO:1903706,GO:1903708,GO:1904888,GO:1905521,GO:1905523,GO:1990834,GO:2000026,GO:2000145,GO:2000147 3.4.24.80 ko:K07763,ko:K07995,ko:K07996,ko:K07997,ko:K08002,ko:K08003 ko04668,ko04912,ko05206,map04668,map04912,map05206 - - - ko00000,ko00001,ko01000,ko01002 - - - DUF3377,Hemopexin,PG_binding_1,Peptidase_M10 k59_130970_2 525903.Taci_1707 7.75e-05 51.6 COG0859@1|root,COG0859@2|Bacteria,3TAC6@508458|Synergistetes 508458|Synergistetes M family 9 - - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 k59_312838_1 497965.Cyan7822_0448 1.77e-26 112.0 COG0553@1|root,COG2263@1|root,COG0553@2|Bacteria,COG2263@2|Bacteria,1G4K0@1117|Cyanobacteria,3KG7H@43988|Cyanothece 1117|Cyanobacteria H C-terminal domain on Strawberry notch homologue - - - - - - - - - - - - AAA_34,Helicase_C_4,MTS k59_142789_5 1165094.RINTHH_3920 6.79e-63 207.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_142789_7 1385658.U5KPZ6_9VIRU 5.44e-206 589.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_291512_1 1234888.K0A2J2_9VIRU 7.49e-71 230.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_83768_3 1034115.G1D5L0_9CAUD 3.47e-18 83.2 4QCF5@10239|Viruses,4QV2A@35237|dsDNA viruses no RNA stage,4QPJI@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_35373_1 573174.M4MBC3_9VIRU 4.85e-93 289.0 4QBY0@10239|Viruses,4QW35@35237|dsDNA viruses no RNA stage 10239|Viruses S AAA domain - - - - - - - - - - - - - k59_35373_2 1327935.A0A060AD26_9CAUD 8.69e-21 92.8 4QE7X@10239|Viruses,4QVF0@35237|dsDNA viruses no RNA stage,4QPUM@28883|Caudovirales,4QI2F@10662|Myoviridae 10662|Myoviridae S Cytidine and deoxycytidylate deaminase zinc-binding region - - - - - - - - - - - - - k59_35373_3 1123247.AUIJ01000009_gene3039 5.14e-14 73.2 COG3773@1|root,COG3773@2|Bacteria,1MWX3@1224|Proteobacteria,2TT15@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Cell wall hydrolyses involved in spore germination sleB - - - - - - - - - - - Hydrolase_2 k59_241193_2 1234888.K0A2J2_9VIRU 4.73e-91 288.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_168273_2 946483.Cenrod_0929 1.11e-06 55.8 COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,2VH1Z@28216|Betaproteobacteria,4AATB@80864|Comamonadaceae 28216|Betaproteobacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease dnaQ - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k59_205031_2 33898.JRHJ01000076_gene397 1.64e-19 87.4 2B7G5@1|root,320K0@2|Bacteria,2GUCA@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_21438_1 1121434.AULY01000011_gene1824 3.41e-84 273.0 COG5362@1|root,COG5362@2|Bacteria,1PYY9@1224|Proteobacteria,435M3@68525|delta/epsilon subdivisions,2WZZT@28221|Deltaproteobacteria,2M981@213115|Desulfovibrionales 28221|Deltaproteobacteria S TIGRFAM Phage - - - - - - - - - - - - - k59_265206_4 1122135.KB893136_gene477 1e-42 145.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2U5BZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_339146_1 1419711.U6BML2_9CIRC 1.43e-10 66.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_291539_1 1986029.Q9MBM8_9VIRU 6.38e-27 114.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_339150_2 1172190.M947_08555 4.51e-05 50.8 COG4627@1|root,COG4627@2|Bacteria,1R035@1224|Proteobacteria,42Q15@68525|delta/epsilon subdivisions,2YRTE@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S overlaps another CDS with the same product name - - - - - - - - - - - - Methyltransf_11 k59_351105_1 691965.D4P7I3_9CAUD 1.72e-32 126.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_254869_2 756276.A0A096VKL9_9VIRU 8.77e-31 120.0 4QBMX@10239|Viruses,4QV9I@35237|dsDNA viruses no RNA stage 10239|Viruses S Pfam:Tube - GO:0005575,GO:0019012 - - - - - - - - - - - k59_279018_1 1449063.JMLS01000001_gene4318 2.81e-06 56.6 COG2366@1|root,COG3386@1|root,COG3420@1|root,COG5492@1|root,COG2366@2|Bacteria,COG3386@2|Bacteria,COG3420@2|Bacteria,COG5492@2|Bacteria,1VR20@1239|Firmicutes,4HVGA@91061|Bacilli,26V79@186822|Paenibacillaceae 91061|Bacilli P Right handed beta helix region - - - - - - - - - - - - Beta_helix,Big_2 k59_242729_1 1223543.GP2_001_00240 7.97e-06 53.1 COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4GCMK@85026|Gordoniaceae 201174|Actinobacteria L DNA polymerase alpha chain like domain dnaE GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k59_109332_5 1234888.K0A2J2_9VIRU 1.41e-118 363.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_254883_1 1788454.A0A190WHE4_9CIRC 4.14e-39 141.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_242736_1 1121451.DESAM_22746 5.58e-22 102.0 COG5362@1|root,COG5362@2|Bacteria,1PYY9@1224|Proteobacteria,435M3@68525|delta/epsilon subdivisions,2WZZT@28221|Deltaproteobacteria,2M981@213115|Desulfovibrionales 28221|Deltaproteobacteria S TIGRFAM Phage - - - - - - - - - - - - - k59_170028_3 643867.Ftrac_3449 8.7e-05 54.3 COG2834@1|root,COG4733@1|root,COG2834@2|Bacteria,COG4733@2|Bacteria,4NWHN@976|Bacteroidetes,47UQ6@768503|Cytophagia 976|Bacteroidetes M Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - VCBS k59_12052_1 1120936.KB907208_gene1069 6.29e-29 114.0 COG3567@1|root,COG3567@2|Bacteria,2H48H@201174|Actinobacteria 201174|Actinobacteria S Phage portal protein, SPP1 Gp6-like - - - - - - - - - - - - Phage_prot_Gp6 k59_279286_2 1692252.A0A0K1RL35_9CIRC 7.71e-88 272.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_121177_3 643562.Daes_0084 2.06e-31 117.0 COG4333@1|root,COG4333@2|Bacteria,1N19M@1224|Proteobacteria,43666@68525|delta/epsilon subdivisions,2X0QD@28221|Deltaproteobacteria,2MD39@213115|Desulfovibrionales 28221|Deltaproteobacteria S Protein of unknown function (DUF1643) - - - - - - - - - - - - DUF1643 k59_12068_1 913865.DOT_1568 2.56e-12 66.6 28MC2@1|root,2ZAQD@2|Bacteria,1VSEU@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - k59_12690_3 1406785.U5PTZ8_9CAUD 1.41e-26 102.0 4QFIE@10239|Viruses,4QUGB@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_12690_9 172045.KS04_01335 9.82e-05 51.2 2EI2J@1|root,33BTZ@2|Bacteria,4NZI5@976|Bacteroidetes,1I6DF@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_110105_1 1548905.A0A0A1IWZ4_9CAUD 3.75e-51 187.0 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_146602_1 1234888.K0A2J2_9VIRU 5.89e-31 120.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_134271_1 1121935.AQXX01000096_gene2527 6.75e-27 117.0 COG5283@1|root,COG5283@2|Bacteria,1QZAD@1224|Proteobacteria,1RYP3@1236|Gammaproteobacteria,1XMG9@135619|Oceanospirillales 135619|Oceanospirillales D nuclear chromosome segregation - - - - - - - - - - - - - k59_122300_4 1121935.AQXX01000130_gene2431 2.02e-38 140.0 2EUDH@1|root,33MVW@2|Bacteria,1NVTR@1224|Proteobacteria,1SP33@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_243595_1 272943.RSP_3792 5.17e-46 156.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2TU8N@28211|Alphaproteobacteria,1FC8X@1060|Rhodobacter 28211|Alphaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_292403_1 742740.HMPREF9474_02306 2.26e-06 51.6 2BPMG@1|root,32IEH@2|Bacteria,1V9DC@1239|Firmicutes,24MC0@186801|Clostridia,2227H@1506553|Lachnoclostridium 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - - k59_292403_2 691965.D4P7I3_9CAUD 0.0 1070.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_292403_3 691965.D4P7I8_9CAUD 4.71e-16 79.3 4QGJH@10239|Viruses,4QZ35@35237|dsDNA viruses no RNA stage,4QRZS@28883|Caudovirales,4QMAA@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_292403_4 691965.D4P7L3_9CAUD 1.41e-112 346.0 4QBH7@10239|Viruses,4QWWF@35237|dsDNA viruses no RNA stage,4QQ8R@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_292403_9 478749.BRYFOR_08535 1.85e-36 130.0 29YRZ@1|root,30KMY@2|Bacteria,1V4Y4@1239|Firmicutes,24HPY@186801|Clostridia 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - DUF2800 k59_762_3 1692244.A0A0K1RLR5_9CIRC 5.26e-91 277.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_219651_2 1788439.A0A190WHD0_9CIRC 3.19e-49 173.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_280418_2 1197951.I6RT34_9CAUD 6.86e-156 452.0 4QGAG@10239|Viruses,4R0KB@35237|dsDNA viruses no RNA stage,4QUA4@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_328906_1 136993.KB900626_gene1843 4.26e-16 80.5 COG4725@1|root,COG4725@2|Bacteria,1R553@1224|Proteobacteria,2TRP6@28211|Alphaproteobacteria,36XZ4@31993|Methylocystaceae 28211|Alphaproteobacteria KT MT-A70 - - - - - - - - - - - - MT-A70,ParBc k59_280419_1 1379719.S5TMX6_9CIRC 9.72e-63 205.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_243602_1 648757.Rvan_3517 3.5e-08 59.7 COG3203@1|root,COG3203@2|Bacteria,1N25J@1224|Proteobacteria,2TYC2@28211|Alphaproteobacteria,3N9J4@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - - - - - - - - - - Porin_4 k59_182786_1 1379708.S5SYC3_9CIRC 7.15e-29 116.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_182786_3 1634476.A0A0F6TGK2_9CIRC 3.92e-39 147.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_281235_1 1609634.A0A0C5AFV4_9VIRU 6.94e-36 135.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_171357_1 1125863.JAFN01000001_gene3558 1.39e-11 73.2 COG1196@1|root,COG3941@1|root,COG1196@2|Bacteria,COG3941@2|Bacteria,1RM55@1224|Proteobacteria,430PQ@68525|delta/epsilon subdivisions,2WVMQ@28221|Deltaproteobacteria 28221|Deltaproteobacteria D Prophage tail length tape measure protein - - - - - - - - - - - - TMP_2,Tape_meas_lam_C k59_244121_1 1788454.A0A190WHE4_9CIRC 3.15e-18 85.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_25546_1 1609634.A0A0C5ANA6_9VIRU 2.55e-09 62.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_147195_1 1283076.M1ICV9_9CAUD 1.34e-50 176.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QI76@10662|Myoviridae 10662|Myoviridae S DNA helicase activity - - - - - - - - - - - - - k59_256457_2 1234888.K0A2J2_9VIRU 5.74e-141 420.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_98501_1 1321784.HMPREF1987_01307 1.65e-15 74.7 COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,24HF9@186801|Clostridia 186801|Clostridia L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_98501_2 926554.KI912617_gene4764 2.96e-24 106.0 2C9JF@1|root,32RPD@2|Bacteria 2|Bacteria S Erf family - - - - - - - - - - - - ERF k59_171359_3 348824.LPU83_1704 1.87e-56 194.0 2BSKA@1|root,32MNV@2|Bacteria,1PFD2@1224|Proteobacteria,2V6B6@28211|Alphaproteobacteria,4BGN5@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_110732_1 1692244.A0A0K1RLR5_9CIRC 6.13e-68 216.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_341342_2 2003327.CAPSD_BPCHP 5.48e-49 185.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_244159_1 424947.U5N122_9CAUD 9.02e-31 124.0 4QAKZ@10239|Viruses,4QPYH@28883|Caudovirales,4QM57@10699|Siphoviridae 10699|Siphoviridae S intein-mediated protein splicing - - - - - - - - - - - - - k59_147233_1 1692249.A0A0K1RL40_9CIRC 2.13e-31 122.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_62925_1 1122132.AQYH01000015_gene2269 1.15e-38 149.0 COG1783@1|root,COG4373@1|root,COG1783@2|Bacteria,COG4373@2|Bacteria,1QUEN@1224|Proteobacteria,2TZM9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Mu-like prophage FluMu protein gp28 - - - - - - - - - - - - - k59_123628_1 936136.ARRT01000006_gene4475 3.37e-23 110.0 COG4383@1|root,COG4383@2|Bacteria,1MWNS@1224|Proteobacteria,2TR0Y@28211|Alphaproteobacteria,4BDT6@82115|Rhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF935) - - - - - - - - - - - - DUF935 k59_1907_1 1385658.U5KPZ6_9VIRU 2.81e-110 339.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_1907_2 1609634.A0A0C5ANA6_9VIRU 6.72e-14 77.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_1907_6 1609634.A0A0C5AFT2_9VIRU 4.62e-124 366.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_269159_3 1410653.JHVC01000014_gene3333 1.42e-21 94.4 COG3409@1|root,COG3409@2|Bacteria,1UIRK@1239|Firmicutes,24KJ0@186801|Clostridia,36JPU@31979|Clostridiaceae 186801|Clostridia M N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2,PG_binding_1 k59_318094_1 1539298.JO41_08220 3.56e-41 140.0 2BYEQ@1|root,32SXE@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_220910_1 145579.CAPSD_BPPHM 6.8e-64 213.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_232702_5 370438.PTH_2877 6.82e-144 438.0 COG0358@1|root,COG3598@1|root,COG0358@2|Bacteria,COG3598@2|Bacteria,1UXUR@1239|Firmicutes,2594M@186801|Clostridia,262BM@186807|Peptococcaceae 186801|Clostridia L DNA primase - - - - - - - - - - - - AAA_25,Toprim_2 k59_232702_7 1123321.KB905819_gene5683 1.17e-29 126.0 2BMCR@1|root,32FWY@2|Bacteria,2GZKQ@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_1962_1 1341181.FLJC2902T_00740 1.23e-22 97.4 COG0207@1|root,COG0207@2|Bacteria,4NEC2@976|Bacteroidetes,1HX2F@117743|Flavobacteriia,2NTB1@237|Flavobacterium 976|Bacteroidetes F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k59_86942_1 1385658.U5KPZ6_9VIRU 8.44e-39 144.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_86942_3 1385658.U5KNR1_9VIRU 8.68e-59 197.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_86942_7 1609634.A0A0C5ANA6_9VIRU 4.44e-15 78.6 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_86942_8 1609634.A0A0C5AFV4_9VIRU 5.34e-172 499.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_366235_1 666681.M301_0132 3.72e-14 79.7 2D784@1|root,32TNH@2|Bacteria,1N098@1224|Proteobacteria,2VX0M@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_366235_2 1411685.U062_00586 2.31e-14 75.1 COG0433@1|root,COG0433@2|Bacteria,1QTVP@1224|Proteobacteria,1T1IQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_220959_1 1331060.RLDS_12065 1.29e-05 51.6 COG0286@1|root,COG0286@2|Bacteria,1RFKR@1224|Proteobacteria,2UQNP@28211|Alphaproteobacteria,2K37Z@204457|Sphingomonadales 204457|Sphingomonadales V N-6 DNA Methylase - - - - - - - - - - - - N6_Mtase k59_135485_2 1547437.LL06_00695 5.49e-29 119.0 COG3299@1|root,COG3299@2|Bacteria,1PYEJ@1224|Proteobacteria,2U8GE@28211|Alphaproteobacteria,43P8G@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Baseplate J-like protein - - - - - - - - - - - - Baseplate_J k59_75433_3 1088864.G8IE98_9CAUD 3.13e-09 62.4 4QBFR@10239|Viruses,4QV1E@35237|dsDNA viruses no RNA stage,4QPRX@28883|Caudovirales,4QKMP@10699|Siphoviridae 10699|Siphoviridae S ERF superfamily - - - - - - - - - - - - - k59_13963_1 309801.trd_A0317 7.93e-12 66.2 COG1686@1|root,COG1686@2|Bacteria,2G8TU@200795|Chloroflexi,27Y7Z@189775|Thermomicrobia 189775|Thermomicrobia M Belongs to the peptidase S11 family - - 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Peptidase_S11 k59_13963_2 1121346.KB899811_gene1650 7.33e-66 221.0 COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,4HACD@91061|Bacilli,26RTS@186822|Paenibacillaceae 91061|Bacilli J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon k59_136208_1 1692255.A0A0K1RL52_9CIRC 2.52e-23 98.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_197094_2 882.DVU_2152 2.34e-06 52.4 2ANZ0@1|root,31E00@2|Bacteria,1P5IP@1224|Proteobacteria,4330C@68525|delta/epsilon subdivisions,2WXQ3@28221|Deltaproteobacteria,2MFMZ@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_282899_1 1046724.KB889899_gene3172 7.25e-09 62.0 COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,1PGZG@1224|Proteobacteria,1RZC4@1236|Gammaproteobacteria,4663W@72275|Alteromonadaceae 1236|Gammaproteobacteria L Pfam:Methyltransf_26 - - - - - - - - - - - - Helicase_C,N6_Mtase,ResIII,SNF2_N,Toprim_3 k59_233407_2 479432.Sros_5339 1.21e-150 437.0 COG1690@1|root,COG1690@2|Bacteria,2GIUP@201174|Actinobacteria,4EGV5@85012|Streptosporangiales 201174|Actinobacteria S tRNA-splicing ligase RtcB rtcB - 6.5.1.3 ko:K14415 - - - - ko00000,ko01000,ko03016 - - - RtcB k59_209572_3 1230457.C476_12066 1.35e-09 62.4 arCOG11413@1|root,arCOG11413@2157|Archaea,2XWQW@28890|Euryarchaeota,23VBV@183963|Halobacteria 183963|Halobacteria S T4-like virus tail tube protein gp19 - - - - - - - - - - - - Phage_T4_gp19 k59_209572_4 298653.Franean1_3816 5.77e-34 132.0 COG3497@1|root,COG3497@2|Bacteria,2GMJA@201174|Actinobacteria,4ES03@85013|Frankiales 201174|Actinobacteria S tail sheath protein - - - ko:K06907 - - - - ko00000 - - - Phage_sheath_1,Phage_sheath_1C k59_172721_1 292459.STH3030 1.15e-61 194.0 COG1738@1|root,COG1738@2|Bacteria,1V8R2@1239|Firmicutes,24K5V@186801|Clostridia 186801|Clostridia S ACR, YhhQ family COG1738 - - - ko:K09125 - - - - ko00000 - - - Vut_1 k59_87664_1 1219035.NT2_13_00580 3.1e-31 124.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_87664_6 1219035.NT2_13_00580 1.03e-33 132.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_330930_5 285535.JOEY01000004_gene10216 3.41e-05 54.3 COG1674@1|root,COG1674@2|Bacteria,2GJA3@201174|Actinobacteria 201174|Actinobacteria D DNA segregation ATPase FtsK SpoIIIE - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE k59_39270_1 1500304.JQKY01000021_gene2039 7.79e-20 87.0 COG1442@1|root,COG1442@2|Bacteria,1QH4S@1224|Proteobacteria,2U9KQ@28211|Alphaproteobacteria,4B9U9@82115|Rhizobiaceae 28211|Alphaproteobacteria M glycosyl transferase family 8 - - - - - - - - - - - - - k59_367264_1 1609634.A0A0C5AFV4_9VIRU 1.29e-82 266.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_148812_4 365659.smi_0179 5.83e-28 108.0 COG0317@1|root,COG0317@2|Bacteria,1VC5K@1239|Firmicutes,4IEB4@91061|Bacilli,2TPZP@28037|Streptococcus mitis 91061|Bacilli KT HD domain - - - - - - - - - - - - - k59_148812_7 1564096.A0A0A0YT02_9CAUD 1.27e-82 261.0 4QC6N@10239|Viruses,4QPEG@28883|Caudovirales,4QI30@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_51774_2 268747.Q58LJ7_BPPRS 2.88e-35 136.0 4QHDM@10239|Viruses,4QYV6@35237|dsDNA viruses no RNA stage,4QRD0@28883|Caudovirales,4QI2W@10662|Myoviridae 10662|Myoviridae S Terminase-like family - GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016032,GO:0016043,GO:0016787,GO:0016788,GO:0019058,GO:0019068,GO:0019069,GO:0019072,GO:0019075,GO:0022607,GO:0032991,GO:0034641,GO:0043170,GO:0043493,GO:0044085,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0046483,GO:0046797,GO:0051704,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0098009,GO:1901360,GO:1902494,GO:1904949 - - - - - - - - - - - k59_124943_3 279238.Saro_2997 3.31e-92 294.0 2C8Q6@1|root,2Z882@2|Bacteria,1PY18@1224|Proteobacteria 1224|Proteobacteria S Phage stabilisation protein - - - - - - - - - - - - Phage_stabilise k59_222182_2 626887.J057_01785 2.33e-69 228.0 2DCM2@1|root,32TZV@2|Bacteria,1NAGE@1224|Proteobacteria,1SMRS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_270382_2 1219035.NT2_13_00580 4.32e-22 96.3 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_173402_2 762660.E5EYJ5_9CAUD 6.86e-16 79.0 4QASV@10239|Viruses,4QWD9@35237|dsDNA viruses no RNA stage,4QQ4N@28883|Caudovirales,4QIBN@10662|Myoviridae 10662|Myoviridae S recA bacterial DNA recombination protein - - - - - - - - - - - - - k59_210203_2 926562.Oweho_2256 9.26e-05 50.1 COG3291@1|root,COG5306@1|root,COG3291@2|Bacteria,COG5306@2|Bacteria,4PP0T@976|Bacteroidetes,1IKE2@117743|Flavobacteriia,2PBMC@246874|Cryomorphaceae 976|Bacteroidetes S domain protein - - - - - - - - - - - - - k59_14508_1 1210908.HSB1_01180 4.29e-32 124.0 arCOG07562@1|root,arCOG07562@2157|Archaea,2XTH6@28890|Euryarchaeota,23U43@183963|Halobacteria 183963|Halobacteria - - - - - - - - - - - - - - - k59_136720_1 1127695.HMPREF9163_00554 1.02e-11 75.1 COG4653@1|root,COG4653@2|Bacteria,1TS6A@1239|Firmicutes 1239|Firmicutes S phage major capsid protein, HK97 family - - - - - - - - - - - - Phage_capsid k59_64283_1 1188795.K7ZJS7_9CAUD 1.03e-32 123.0 4QHDA@10239|Viruses,4R08R@35237|dsDNA viruses no RNA stage,4QRRI@28883|Caudovirales,4QNP3@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_39817_4 1609634.A0A0C5ANA6_9VIRU 5.85e-20 91.7 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_39817_5 1609634.A0A0C5AFV4_9VIRU 1.42e-224 637.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_343862_1 1219035.NT2_13_00580 3.71e-31 125.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_319969_1 351016.RAZWK3B_16630 5.9e-153 491.0 COG0553@1|root,COG0827@1|root,COG1040@1|root,COG1203@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG1040@2|Bacteria,COG1203@2|Bacteria,1MXQH@1224|Proteobacteria 1224|Proteobacteria KL methylase - - - - - - - - - - - - AAA_34,Helicase_C,Helicase_C_4,ResIII k59_64835_1 1385658.U5KPZ6_9VIRU 2.43e-41 153.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_246563_2 794903.OPIT5_04015 2.11e-25 107.0 2CJW6@1|root,32SAX@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_307657_4 1609634.A0A0C5AFV4_9VIRU 7.01e-122 372.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_76649_1 145579.CAPSD_BPPHM 3.96e-70 228.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_343925_1 1166018.FAES_4368 2.35e-09 64.3 COG0464@1|root,COG0464@2|Bacteria,4NPXE@976|Bacteroidetes,47NWY@768503|Cytophagia 976|Bacteroidetes O ATPase family associated with various cellular activities (AAA) - - - - - - - - - - - - AAA k59_343926_1 753085.F4YCV3_9CAUD 1.28e-74 246.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_64870_1 1242864.D187_008748 4.06e-45 160.0 COG0338@1|root,COG0338@2|Bacteria,1Q9YJ@1224|Proteobacteria,438CP@68525|delta/epsilon subdivisions,2X1WK@28221|Deltaproteobacteria,2YWK0@29|Myxococcales 28221|Deltaproteobacteria L D12 class N6 adenine-specific DNA methyltransferase - - - - - - - - - - - - MethyltransfD12 k59_15078_1 1120963.KB894501_gene316 1.83e-25 100.0 COG2852@1|root,COG2852@2|Bacteria,1N7EJ@1224|Proteobacteria,1SF5D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - DUF559 k59_64873_1 1609634.A0A0C5ANA6_9VIRU 5.46e-11 66.2 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_356156_1 1385658.U5KNR1_9VIRU 4.4e-14 74.7 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_356156_3 1385658.U5KPZ6_9VIRU 2.37e-124 378.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_380422_1 1476973.JMMB01000007_gene1771 5.37e-33 131.0 COG5283@1|root,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,25MTJ@186801|Clostridia,25SYM@186804|Peptostreptococcaceae 186801|Clostridia S Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_113030_1 1692244.A0A0K1RLR5_9CIRC 1.26e-95 289.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_39923_3 1220589.CD32_09085 4.26e-07 58.2 COG0451@1|root,COG0451@2|Bacteria,1V34Y@1239|Firmicutes,4HCJE@91061|Bacilli,3J09N@400634|Lysinibacillus 91061|Bacilli GM Male sterility protein - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GAF_3,GDP_Man_Dehyd k59_320628_2 1692242.A0A0K1RL37_9CIRC 9.74e-56 185.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_137878_1 1609634.A0A0C5AFV4_9VIRU 1.03e-52 184.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_308281_1 1556290.A0A0A0RT35_9CAUD 1.32e-73 233.0 4QAWG@10239|Viruses,4QPII@28883|Caudovirales,4QKWY@10699|Siphoviridae 10699|Siphoviridae S DNA helicase activity - - - - - - - - - - - - - k59_344550_1 445696.E3SSP3_9CAUD 8.72e-11 67.0 4QB5I@10239|Viruses 10239|Viruses S N-methyltransferase activity - - - - - - - - - - - - - k59_40491_2 1540257.JQMW01000009_gene2673 5.8e-11 62.4 2EUFA@1|root,33MXK@2|Bacteria,1VQFP@1239|Firmicutes,24S0X@186801|Clostridia,36N6B@31979|Clostridiaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_285106_4 460265.Mnod_4233 3.88e-61 206.0 COG0468@1|root,COG0468@2|Bacteria,1PXGB@1224|Proteobacteria,2V21B@28211|Alphaproteobacteria,1JXXV@119045|Methylobacteriaceae 28211|Alphaproteobacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - - - - - - - - - - - k59_15602_1 1609634.A0A0C5AFT2_9VIRU 2.92e-72 227.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_162452_3 1385658.U5KPZ6_9VIRU 3.38e-185 537.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_235135_2 948071.S4S2M5_9CAUD 2.54e-34 128.0 4QBD3@10239|Viruses,4QXFU@35237|dsDNA viruses no RNA stage,4QQ7Z@28883|Caudovirales,4QNS1@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_101738_1 936136.ARRT01000006_gene5340 4.34e-74 241.0 COG1783@1|root,COG1783@2|Bacteria,1RAGC@1224|Proteobacteria,2U6JF@28211|Alphaproteobacteria,4BID4@82115|Rhizobiaceae 28211|Alphaproteobacteria S phage Terminase large subunit - - - - - - - - - - - - - k59_65378_1 1370122.JHXQ01000018_gene69 7.62e-26 105.0 2EHNC@1|root,33BE4@2|Bacteria,1R1ZS@1224|Proteobacteria,2TZ7V@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_259340_6 1384056.N787_06840 5.26e-07 56.2 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,1X4NS@135614|Xanthomonadales 135614|Xanthomonadales M Lytic murein transglycosylase slt - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT,SLT_L k59_332654_1 1385658.U5KNR1_9VIRU 1.68e-81 255.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_332654_5 1986029.Q9MBM8_9VIRU 1.11e-29 116.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_90350_1 520709.F985_01890 1.7e-84 261.0 COG0270@1|root,COG0270@2|Bacteria,1N0XD@1224|Proteobacteria,1T05A@1236|Gammaproteobacteria 1236|Gammaproteobacteria L C-5 cytosine-specific DNA methylase - - - - - - - - - - - - DNA_methylase k59_345346_1 448385.sce7823 8.47e-09 57.8 COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,42R0K@68525|delta/epsilon subdivisions,2WMTU@28221|Deltaproteobacteria,2Z309@29|Myxococcales 28221|Deltaproteobacteria M Cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C k59_345346_2 452471.Aasi_1031 6.83e-07 52.4 COG1108@1|root,COG1321@1|root,COG1108@2|Bacteria,COG1321@2|Bacteria,4NH3D@976|Bacteroidetes,47MU3@768503|Cytophagia 976|Bacteroidetes KP ABC 3 transport family mntC - - ko:K11708 ko02010,map02010 M00319 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15 - - ABC-3,Fe_dep_repr_C k59_309064_1 1449347.JQLN01000004_gene7007 8.8e-43 157.0 COG5323@1|root,COG5323@2|Bacteria,2I1XF@201174|Actinobacteria,2M5NQ@2063|Kitasatospora 201174|Actinobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_41333_1 1327990.S0A3Y5_9CAUD 1.14e-16 83.2 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNBK@10744|Podoviridae 10744|Podoviridae S Ribonucleotide reductase, barrel domain - - - - - - - - - - - - - k59_41333_2 862965.PARA_04430 6.68e-06 47.8 COG1694@1|root,COG1694@2|Bacteria,1NBT1@1224|Proteobacteria,1TFI9@1236|Gammaproteobacteria,1Y937@135625|Pasteurellales 135625|Pasteurellales S protein of Mannheimia haemolytica PHL213 UniRef RepID A7JSI2_PASHA - - - - - - - - - - - - MazG k59_286105_1 714313.LSA_09940 0.00016 47.8 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4HATQ@91061|Bacilli,3F44X@33958|Lactobacillaceae 91061|Bacilli L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k59_16300_1 1498011.A0A096XUV3_9CAUD 3.49e-09 62.0 4QAUS@10239|Viruses,4QQ2S@28883|Caudovirales 28883|Caudovirales S flavin adenine dinucleotide binding - - - - - - - - - - - - - k59_53714_1 765698.Mesci_3812 2.54e-35 130.0 2C22H@1|root,30QGC@2|Bacteria,1PKNY@1224|Proteobacteria,2UZAT@28211|Alphaproteobacteria,43PHR@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Chaperone of endosialidase - - - - - - - - - - - - Peptidase_S74 k59_150939_2 467661.RKLH11_958 1.72e-72 223.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2TU8N@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_42086_1 608538.HTH_0614 8.44e-14 76.6 COG0305@1|root,COG0305@2|Bacteria,2G3QP@200783|Aquificae 200783|Aquificae L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_236365_1 1609634.A0A0C5AFV4_9VIRU 2.15e-17 82.8 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_236365_2 105154.Q9MBU3_9VIRU 3.23e-08 60.5 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_200243_1 2003327.CAPSD_BPCHP 2.44e-17 89.4 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_273135_1 1238186.AOCN01000026_gene2066 7.37e-14 75.1 COG0739@1|root,COG0739@2|Bacteria,2GXEC@201174|Actinobacteria,4FPUU@85023|Microbacteriaceae 201174|Actinobacteria M Peptidase family M23 nlpD - - - - - - - - - - - Peptidase_M23 k59_186153_1 691965.D4P7C5_9CAUD 8.75e-102 311.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_151701_4 1047013.AQSP01000144_gene795 1.35e-07 53.9 COG0399@1|root,COG0399@2|Bacteria,2NQEF@2323|unclassified Bacteria 2|Bacteria M DegT/DnrJ/EryC1/StrS aminotransferase family - - - - - - - - - - - - DegT_DnrJ_EryC1 k59_176250_6 226185.EF_0330 1.48e-93 298.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H9YP@91061|Bacilli,4B1S9@81852|Enterococcaceae 91061|Bacilli KL SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_176250_9 1457393.AZ09_10465 6.63e-26 106.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2TU8N@28211|Alphaproteobacteria,2JXEZ@204441|Rhodospirillales 204441|Rhodospirillales L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_42146_3 1122176.KB903531_gene2762 8.22e-09 68.9 COG1572@1|root,COG4447@1|root,COG1572@2|Bacteria,COG4447@2|Bacteria 2|Bacteria S cellulose binding - - 3.2.1.51 ko:K15923 ko00511,map00511 - - - ko00000,ko00001,ko01000 - GH95 - Laminin_G_3,TM_helix k59_114881_1 1344012.ATMI01000031_gene2805 4.44e-15 76.3 2CJWY@1|root,31CWF@2|Bacteria,1RKEF@1224|Proteobacteria,1S75P@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_357942_5 1510531.JQJJ01000011_gene2883 1.31e-19 90.9 COG3179@1|root,COG3179@2|Bacteria,1R71F@1224|Proteobacteria,2V8ZW@28211|Alphaproteobacteria,3K5PW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S chitinase - - - - - - - - - - - - - k59_91322_2 349123.Lreu23DRAFT_4711 1.31e-06 50.8 COG1476@1|root,COG1476@2|Bacteria,1VEKB@1239|Firmicutes,4HNIW@91061|Bacilli,3F6AB@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_3 k59_16878_1 323098.Nwi_1543 6.61e-15 77.0 COG0740@1|root,COG0740@2|Bacteria,1MUQ9@1224|Proteobacteria,2U37W@28211|Alphaproteobacteria,3K40K@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria OU Serine dehydrogenase proteinase - - - - - - - - - - - - CLP_protease k59_382303_1 186617.M9M8L2_9VIRU 1.55e-14 73.9 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_382303_3 1385658.U5KNR1_9VIRU 5.52e-45 160.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_67554_1 186617.M9M8L2_9VIRU 1.55e-122 365.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_6759_1 1609634.A0A0C5AFV4_9VIRU 3e-57 195.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_237034_2 1788439.A0A190WHD0_9CIRC 5.32e-31 125.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_334857_1 595536.ADVE02000001_gene1745 2.04e-35 131.0 COG0175@1|root,COG0175@2|Bacteria,1QZJ1@1224|Proteobacteria,2U233@28211|Alphaproteobacteria 28211|Alphaproteobacteria EH sulfate reduction - - - - - - - - - - - - - k59_370723_1 438753.AZC_3598 9.42e-59 203.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT52@1224|Proteobacteria,2TVNI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_2 k59_346920_2 945712.CULC22_01805 6.29e-13 68.6 2FJV8@1|root,34BHS@2|Bacteria,2GTIC@201174|Actinobacteria,22R68@1653|Corynebacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_103856_3 1385658.U5KPZ6_9VIRU 2.94e-113 346.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_200945_2 478749.BRYFOR_07810 8.9e-19 88.2 COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia 186801|Clostridia L Belongs to the 'phage' integrase family xerC - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k59_55165_1 186617.M9M8L2_9VIRU 7.04e-51 176.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_128411_2 1234881.K0A1K7_9CIRC 5.81e-05 46.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_273928_1 76869.PputGB1_1751 1.23e-06 52.4 28HXV@1|root,2Z83C@2|Bacteria,1PJBP@1224|Proteobacteria,1RYDU@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_287790_1 1131462.DCF50_p2624 7.11e-41 153.0 COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,25ZYN@186807|Peptococcaceae 186801|Clostridia J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS - 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k59_115558_2 1385658.U5KNR1_9VIRU 5.71e-53 180.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_273931_1 756499.Desde_2689 2.85e-47 157.0 COG1738@1|root,COG1738@2|Bacteria,1V8R2@1239|Firmicutes,24K5V@186801|Clostridia,264VZ@186807|Peptococcaceae 186801|Clostridia S Putative vitamin uptake transporter - - - ko:K09125 - - - - ko00000 - - - Vut_1 k59_92207_2 1036616.G1DUU3_9CAUD 3.15e-20 84.0 4QCCA@10239|Viruses,4QY28@35237|dsDNA viruses no RNA stage,4QU0Q@28883|Caudovirales,4QNA0@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_67669_1 1244869.H261_16912 8.93e-29 118.0 COG2404@1|root,COG2404@2|Bacteria,1MXEH@1224|Proteobacteria,2U76B@28211|Alphaproteobacteria 28211|Alphaproteobacteria S phosphoesterase DHHA1 - - - - - - - - - - - - DHHA1 k59_334926_1 160799.PBOR_24090 2.85e-05 51.6 2EPXN@1|root,33HI6@2|Bacteria,1VVBP@1239|Firmicutes,4HW76@91061|Bacilli,26WQP@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - k59_225925_1 1226994.AMZB01000079_gene96 3.45e-05 52.0 2CZBU@1|root,32T60@2|Bacteria,1N7TC@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_80362_4 1005395.CSV86_06226 3.75e-21 95.1 COG3206@1|root,COG3206@2|Bacteria,1ND5H@1224|Proteobacteria,1RNXC@1236|Gammaproteobacteria 1236|Gammaproteobacteria M DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - - - - - - - - - - - Rad52_Rad22 k59_80362_5 700598.Niako_1586 1.25e-06 52.0 COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes 976|Bacteroidetes L single-stranded DNA-binding protein ssb1 - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_80362_8 935565.JAEM01000006_gene3908 3.91e-118 360.0 COG0827@1|root,COG0827@2|Bacteria,1R5Y7@1224|Proteobacteria,2VEZS@28211|Alphaproteobacteria,2PX5N@265|Paracoccus 28211|Alphaproteobacteria L Domain of unknown function (DUF4942) - - - - - - - - - - - - DUF4942,MTS k59_80362_10 1280941.HY2_11830 1.71e-15 88.6 COG1475@1|root,COG1475@2|Bacteria,1MVF9@1224|Proteobacteria,2TR0P@28211|Alphaproteobacteria,43XC6@69657|Hyphomonadaceae 28211|Alphaproteobacteria K ParB-like nuclease domain - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_214754_1 511.JT27_18510 5.98e-98 309.0 COG5518@1|root,COG5518@2|Bacteria,1MYGZ@1224|Proteobacteria 1224|Proteobacteria S Phage portal protein, PBSX family - - - - - - - - - - - - Phage_portal k59_347762_1 1540097.A0A0A0YWA1_9CAUD 8.3e-50 172.0 4QCT5@10239|Viruses,4QTPG@28883|Caudovirales,4QNK2@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_335792_4 1234888.K0A2J2_9VIRU 2.18e-69 238.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_80410_1 1385658.U5KPZ6_9VIRU 2.78e-124 380.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_226751_2 1609634.A0A0C5AFT2_9VIRU 1.64e-101 305.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_274679_1 1242864.D187_002821 1.61e-09 66.6 COG4733@1|root,COG4733@2|Bacteria,1QX65@1224|Proteobacteria,43BYR@68525|delta/epsilon subdivisions,2X79M@28221|Deltaproteobacteria,2YZ8E@29|Myxococcales 28221|Deltaproteobacteria G Fibronectin type III domain - - - - - - - - - - - - fn3 k59_93213_1 1120936.KB907208_gene1107 1.99e-77 251.0 COG0209@1|root,COG0209@2|Bacteria,2IC1H@201174|Actinobacteria 201174|Actinobacteria F Ribonucleotide reductase, barrel domain - - - - - - - - - - - - Ribonuc_red_lgC k59_177989_2 1385658.U5KNR1_9VIRU 1.16e-18 88.6 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_18382_1 269796.Rru_A1463 3.21e-10 64.7 COG0438@1|root,COG0438@2|Bacteria,1QY7T@1224|Proteobacteria,2TXJ6@28211|Alphaproteobacteria,2JYV2@204441|Rhodospirillales 204441|Rhodospirillales M Sulfotransferase domain - - 2.8.2.1 ko:K01014 ko05204,map05204 - R01242 RC00007,RC00128 ko00000,ko00001,ko01000 - - - Sulfotransfer_1 k59_383562_1 1123269.NX02_21995 8.35e-21 91.3 COG0553@1|root,COG0553@2|Bacteria,1R7CK@1224|Proteobacteria,2U228@28211|Alphaproteobacteria,2KA8N@204457|Sphingomonadales 204457|Sphingomonadales KL DEAD-like helicases superfamily - - - - - - - - - - - - - k59_19265_1 3885.XP_007140240.1 2.23e-11 66.6 COG0484@1|root,KOG0714@2759|Eukaryota,37QCW@33090|Viridiplantae,3GCGF@35493|Streptophyta,4JK8Y@91835|fabids 35493|Streptophyta O DnaJ molecular chaperone homology domain - GO:0000003,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005783,GO:0005788,GO:0005911,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009506,GO:0009628,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0012505,GO:0016043,GO:0016049,GO:0016491,GO:0022414,GO:0030054,GO:0030154,GO:0031974,GO:0032501,GO:0032502,GO:0032989,GO:0033554,GO:0034605,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044706,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050896,GO:0051704,GO:0051716,GO:0055044,GO:0055114,GO:0060560,GO:0070013,GO:0071840 - - - - - - - - - - DnaJ k59_348838_1 1461694.ATO9_04000 4.77e-32 124.0 2BRNJ@1|root,32KN6@2|Bacteria,1RJQ1@1224|Proteobacteria,2U9AF@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_348838_2 426117.M446_3324 1.4e-08 59.3 COG1403@1|root,COG1403@2|Bacteria,1NGV5@1224|Proteobacteria,2UMQJ@28211|Alphaproteobacteria,1JWF5@119045|Methylobacteriaceae 28211|Alphaproteobacteria V HNH nucleases - - - - - - - - - - - - HNH k59_348840_1 1340493.JNIF01000003_gene2420 1.55e-11 70.9 2DP40@1|root,330F7@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_179050_1 1235813.JCM10003_3774 1.73e-21 97.1 COG3969@1|root,COG3969@2|Bacteria,4NJR7@976|Bacteroidetes,2FMUJ@200643|Bacteroidia,4AMYJ@815|Bacteroidaceae 976|Bacteroidetes S Phosphoadenosine phosphosulfate reductase family - - - - - - - - - - - - DUF3440,PAPS_reduct k59_69445_2 1415780.JPOG01000001_gene1744 2.59e-23 110.0 COG0454@1|root,COG0827@1|root,COG1040@1|root,COG3087@1|root,COG0456@2|Bacteria,COG0827@2|Bacteria,COG1040@2|Bacteria,COG3087@2|Bacteria,1PI1K@1224|Proteobacteria,1T6BU@1236|Gammaproteobacteria,1XB7I@135614|Xanthomonadales 135614|Xanthomonadales D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - - - - - - - - - - - k59_19269_2 4792.ETI31775 7.53e-70 235.0 2C7RP@1|root,2SPXE@2759|Eukaryota 2759|Eukaryota - - - - - - - - - - - - - - - k59_56976_1 1120948.KB903243_gene2721 6.53e-16 89.4 COG3266@1|root,COG3266@2|Bacteria,2I302@201174|Actinobacteria,4EF87@85010|Pseudonocardiales 201174|Actinobacteria S response to copper ion - - - - - - - - - - - - Big_5,DUF4082 k59_56976_2 476272.RUMHYD_03672 3.12e-06 57.0 COG2931@1|root,COG2931@2|Bacteria,1TSGB@1239|Firmicutes,247TS@186801|Clostridia 186801|Clostridia Q PFAM Collagen triple helix - - - - - - - - - - - - Collagen k59_56976_5 365044.Pnap_3115 0.000174 50.8 COG3420@1|root,COG3420@2|Bacteria,1QWWH@1224|Proteobacteria,2W243@28216|Betaproteobacteria 1224|Proteobacteria P Protein of unknown function (DUF1565) - - - - - - - - - - - - Beta_helix,DUF1565,DUF4082 k59_360237_2 469378.Ccur_14140 2.58e-13 80.1 COG1475@1|root,COG1475@2|Bacteria,2GNRN@201174|Actinobacteria,4CUFM@84998|Coriobacteriia 84998|Coriobacteriia K Belongs to the ParB family - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_360237_3 1519439.JPJG01000059_gene1913 7.31e-13 64.3 2CHCE@1|root,32Z7E@2|Bacteria,1VIXB@1239|Firmicutes,24TNE@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_360237_6 1123276.KB893248_gene4 0.000362 46.2 2EQ06@1|root,340RM@2|Bacteria,4PQ0X@976|Bacteroidetes,47YT4@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_117332_2 1234888.K0A2J2_9VIRU 4.08e-28 113.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_312246_1 1234888.K0A2J2_9VIRU 4.62e-173 503.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_312246_2 1234888.K0A2R8_9VIRU 2.29e-44 157.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_142104_1 97139.C824_05171 4.98e-06 50.1 COG0615@1|root,COG0615@2|Bacteria,1V3KY@1239|Firmicutes,24HAQ@186801|Clostridia,36M3N@31979|Clostridiaceae 186801|Clostridia IM Cytidylyltransferase-like - - - - - - - - - - - - CTP_transf_like k59_324863_1 349965.yinte0001_8640 4.75e-92 282.0 COG4249@1|root,COG4249@2|Bacteria,1QPXG@1224|Proteobacteria,1S1R1@1236|Gammaproteobacteria,41GXS@629|Yersinia 1236|Gammaproteobacteria S Caspase domain - - - - - - - - - - - - Peptidase_C14 k59_300661_1 390333.Ldb0824 2.51e-49 185.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H9YP@91061|Bacilli,3FCEQ@33958|Lactobacillaceae 91061|Bacilli L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_57080_1 666686.B1NLA3E_04990 1.05e-16 85.1 COG4641@1|root,COG4641@2|Bacteria,1UWN6@1239|Firmicutes,4HAGV@91061|Bacilli,1ZEYP@1386|Bacillus 91061|Bacilli S Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_2 k59_8958_11 102232.GLO73106DRAFT_00001460 1.79e-05 49.3 COG1403@1|root,COG3344@1|root,COG1403@2|Bacteria,COG3344@2|Bacteria,1G065@1117|Cyanobacteria 1117|Cyanobacteria L reverse transcriptase - - 2.7.7.49 ko:K00986 - - - - ko00000,ko01000 - - - GIIM,HNH,RVT_1,RVT_N k59_349573_7 1197951.I6R9K8_9CAUD 1.17e-124 366.0 4QFIC@10239|Viruses,4QXG2@35237|dsDNA viruses no RNA stage,4QTVA@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_373240_2 1004785.AMBLS11_04835 1.44e-11 69.7 28K7U@1|root,2Z9VT@2|Bacteria,1RFB2@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_33784_1 935837.JAEK01000014_gene5134 7.4e-26 109.0 COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,1ZBDZ@1386|Bacillus 91061|Bacilli D Belongs to the SEDS family ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE k59_349601_13 521000.PROVRETT_05969 5.29e-18 84.0 2DIG9@1|root,3036R@2|Bacteria,1RBPA@1224|Proteobacteria,1S2FC@1236|Gammaproteobacteria 1236|Gammaproteobacteria L YqaJ-like viral recombinase domain - - - - - - - - - - - - YqaJ k59_9007_2 1618238.A0A0C5IB41_9CIRC 8.24e-16 81.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_325654_1 1439940.BAY1663_02360 5.47e-23 97.8 28JTG@1|root,2Z9IR@2|Bacteria,1PCXZ@1224|Proteobacteria,1SIJB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_290370_4 1401297.U3PDJ9_9CAUD 7.61e-42 150.0 4QARC@10239|Viruses,4QV4E@35237|dsDNA viruses no RNA stage,4QPDS@28883|Caudovirales,4QP0H@10744|Podoviridae 10744|Podoviridae S nucleic acid binding - - - - - - - - - - - - - k59_290370_7 66875.JODY01000031_gene4098 1.84e-10 67.8 COG0739@1|root,COG0739@2|Bacteria,2GW9V@201174|Actinobacteria 201174|Actinobacteria M heme binding - - - - - - - - - - - - Amidase_2 k59_290370_9 253839.SSNG_02588 2.08e-09 56.6 2C3CA@1|root,2ZUNU@2|Bacteria,2GZBJ@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_290370_18 1121090.KB894694_gene2091 1.02e-30 136.0 COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1TPFZ@1239|Firmicutes,4HAIF@91061|Bacilli,1ZBZT@1386|Bacillus 91061|Bacilli L COG0553 Superfamily II DNA RNA helicases, SNF2 family snf - - - - - - - - - - - Helicase_C,SNF2_N,SNF2_assoc,SWIM k59_180887_1 1986029.Q9MBM3_9VIRU 2.61e-47 166.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_167825_2 643867.Ftrac_3748 7.68e-08 54.3 2DMPT@1|root,32SXV@2|Bacteria,4PKGT@976|Bacteroidetes,47R1K@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF3127) - - - - - - - - - - - - DUF3127 k59_156388_5 1636271.A0A0E3M3Z6_9CAUD 6.14e-43 149.0 4QFVK@10239|Viruses,4QSUR@28883|Caudovirales,4QM8N@10699|Siphoviridae 10699|Siphoviridae S transferase activity - - - - - - - - - - - - - k59_83248_1 1337936.IJ00_28010 7.64e-05 45.1 COG1396@1|root,COG1396@2|Bacteria,1GB6V@1117|Cyanobacteria 1117|Cyanobacteria K Helix-turn-helix domain - - - - - - - - - - - - HTH_37 k59_204586_1 1123020.AUIE01000007_gene3218 7.87e-41 154.0 COG3391@1|root,COG3391@2|Bacteria,1MXN7@1224|Proteobacteria 1224|Proteobacteria M Gene transfer agent - - - - - - - - - - - - Phage-tail_3 k59_71086_1 1524880.A0A076G5J7_9VIRU 7.53e-14 75.1 4QE8X@10239|Viruses 10239|Viruses S Phage phiEco32-like COOH.NH2 ligase-type 2 - - - - - - - - - - - - - k59_350494_1 1121479.AUBS01000073_gene1861 1.34e-64 204.0 COG1961@1|root,COG1961@2|Bacteria,1MXXT@1224|Proteobacteria,2U9WZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Site-specific recombinases, DNA invertase Pin homologs - - - ko:K14060 - - - - ko00000 - - - Resolvase k59_9863_2 1114856.C496_09941 4.03e-16 86.7 COG0210@1|root,arCOG00797@2157|Archaea,2XUH7@28890|Euryarchaeota,23S3W@183963|Halobacteria 183963|Halobacteria L COG0210 Superfamily I DNA and RNA helicases uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k59_107300_1 1417599.U6C6F9_9CAUD 1.4e-118 355.0 4QBD3@10239|Viruses,4QXFU@35237|dsDNA viruses no RNA stage,4QQ7Z@28883|Caudovirales,4QNJ0@10744|Podoviridae 10744|Podoviridae S P22 coat protein - gene protein 5 - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0009987,GO:0016032,GO:0016043,GO:0019012,GO:0019028,GO:0019030,GO:0019058,GO:0019068,GO:0019069,GO:0019075,GO:0022607,GO:0039620,GO:0042802,GO:0042803,GO:0044085,GO:0044403,GO:0044419,GO:0044423,GO:0046729,GO:0046797,GO:0046983,GO:0051704,GO:0071840 - - - - - - - - - - - k59_314077_1 397945.Aave_2383 7.56e-09 64.3 COG0454@1|root,COG0503@1|root,COG0827@1|root,COG0456@2|Bacteria,COG0503@2|Bacteria,COG0827@2|Bacteria,1PE9Y@1224|Proteobacteria,2VP0T@28216|Betaproteobacteria,4AGXR@80864|Comamonadaceae 28216|Betaproteobacteria K Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis - - - - - - - - - - - - - k59_229639_3 1519439.JPJG01000027_gene597 2.44e-33 132.0 COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,2N6XG@216572|Oscillospiraceae 186801|Clostridia J Probable RNA and SrmB- binding site of polymerase A cca - 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 - - - HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2 k59_314078_1 411901.BACCAC_02358 2.27e-08 60.5 COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,2FNFH@200643|Bacteroidia,4AMQJ@815|Bacteroidaceae 976|Bacteroidetes L Participates in initiation and elongation during chromosome replication - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_291127_1 1385658.U5KPZ6_9VIRU 2.83e-202 576.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_156405_1 1445726.W0LNS9_9CAUD 3.54e-11 66.6 4QBP3@10239|Viruses,4QPEQ@28883|Caudovirales,4QM06@10699|Siphoviridae 10699|Siphoviridae S PDDEXK-like domain of unknown function (DUF3799) - - - - - - - - - - - - - k59_167838_1 1122201.AUAZ01000017_gene2908 9.82e-15 77.0 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,46560@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) fabG GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0030497,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - iAF1260.b1093,iAPECO1_1312.APECO1_174,iBWG_1329.BWG_0941,iE2348C_1286.E2348C_1185,iEC55989_1330.EC55989_1205,iECABU_c1320.ECABU_c13060,iECDH10B_1368.ECDH10B_1165,iECDH1ME8569_1439.ECDH1ME8569_1028,iECED1_1282.ECED1_1236,iECIAI39_1322.ECIAI39_2068,iECNA114_1301.ECNA114_1150,iECO103_1326.ECO103_1138,iECOK1_1307.ECOK1_1200,iECP_1309.ECP_1085,iECS88_1305.ECS88_1107,iECSE_1348.ECSE_1157,iECSF_1327.ECSF_0992,iECUMN_1333.ECUMN_1268,iECW_1372.ECW_m1201,iEKO11_1354.EKO11_2741,iETEC_1333.ETEC_1158,iEcDH1_1363.EcDH1_2554,iEcE24377_1341.EcE24377A_1214,iEcHS_1320.EcHS_A1215,iEcSMS35_1347.EcSMS35_2034,iEcolC_1368.EcolC_2508,iG2583_1286.G2583_1353,iJN746.PP_1914,iJO1366.b1093,iJR904.b1093,iSBO_1134.SBO_1970,iSFV_1184.SFV_1113,iSF_1195.SF1097,iSFxv_1172.SFxv_1249,iSSON_1240.SSON_1113,iS_1188.S1177,iSbBS512_1146.SbBS512_E2231,iUMN146_1321.UM146_11860,iUMNK88_1353.UMNK88_1363,iUTI89_1310.UTI89_C1218,iWFL_1372.ECW_m1201,iY75_1357.Y75_RS05710 adh_short_C2 k59_230530_2 926550.CLDAP_29840 2.61e-25 119.0 COG3023@1|root,COG4423@1|root,COG3023@2|Bacteria,COG4423@2|Bacteria 2|Bacteria S positive regulation of growth - - - ko:K19687 - - - - ko00000,ko02048 - - - Amidase_2,PG_binding_1,PSK_trans_fac k59_230531_2 1297569.MESS2_1220034 2.04e-44 152.0 COG1442@1|root,COG1442@2|Bacteria,1QH4S@1224|Proteobacteria,2U9KQ@28211|Alphaproteobacteria,43JIY@69277|Phyllobacteriaceae 28211|Alphaproteobacteria M glycosyl transferase family 8 - - - - - - - - - - - - - k59_35781_1 35703.DQ02_13760 5.06e-24 99.0 COG4570@1|root,COG4570@2|Bacteria,1RH5J@1224|Proteobacteria,1S7I6@1236|Gammaproteobacteria 1236|Gammaproteobacteria L endodeoxyribonuclease RusA - - - - - - - - - - - - RusA k59_327528_1 438753.AZC_3597 1.59e-68 226.0 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,2TVEI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA polymerase family A - - - - - - - - - - - - DNA_pol_A k59_278222_1 1562701.BBOF01000081_gene238 1.21e-46 171.0 COG0553@1|root,COG0553@2|Bacteria,1PN7I@1224|Proteobacteria,2VP2N@28216|Betaproteobacteria,1KDPX@119060|Burkholderiaceae 28216|Betaproteobacteria KL Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair - - - - - - - - - - - - SNF2_N k59_314930_3 1234888.K0A2J2_9VIRU 1.9e-114 352.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_265608_2 742767.HMPREF9456_00453 2.54e-35 127.0 COG0561@1|root,COG0561@2|Bacteria,4PKY8@976|Bacteroidetes,2FU2C@200643|Bacteroidia 976|Bacteroidetes S phosphatase activity - - - - - - - - - - - - - k59_387038_1 68170.KL590474_gene5959 5.39e-67 214.0 COG2887@1|root,COG2887@2|Bacteria,2IBTP@201174|Actinobacteria,4E5WP@85010|Pseudonocardiales 201174|Actinobacteria L Belongs to the helicase family. UvrD subfamily - - - - - - - - - - - - PDDEXK_1 k59_327645_3 1609634.A0A0C5AFV4_9VIRU 1.24e-131 394.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_84476_3 1505227.A0A076GAF9_9CAUD 8.07e-46 150.0 4QGQX@10239|Viruses,4QQ2D@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_242603_2 1123242.JH636435_gene3075 5.37e-23 102.0 COG0568@1|root,COG0568@2|Bacteria,2J2AT@203682|Planctomycetes 203682|Planctomycetes K Sigma-70 factor, region 1.1 - - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k59_206207_7 742733.HMPREF9469_05020 1.61e-173 584.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,221IX@1506553|Lachnoclostridium 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_206207_8 478749.BRYFOR_08514 1.16e-29 110.0 2ARVA@1|root,31H70@2|Bacteria,1V7JT@1239|Firmicutes,24JPE@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - HK97-gp10_like k59_206207_11 742733.HMPREF9469_05023 1.17e-34 127.0 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia,222RY@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_206207_12 1476888.X4Y7Z1_9CAUD 9.03e-74 235.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_206207_15 691965.D4P7D6_9CAUD 5.29e-132 407.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_278969_1 662755.CRES_0693 1.04e-44 162.0 COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,22KFN@1653|Corynebacteriaceae 201174|Actinobacteria J Catalyzes the attachment of glycine to tRNA(Gly) glyQS GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 ko:K01880 ko00970,map00970 M00359,M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - HGTP_anticodon,tRNA-synt_2b k59_242661_1 1609634.A0A0C5AFT2_9VIRU 1.6e-71 228.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_388041_2 105154.Q9MBU6_9VIRU 6.88e-224 636.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_190531_1 1246459.KB898357_gene1632 7.08e-16 81.3 COG5301@1|root,COG5301@2|Bacteria,1N6XX@1224|Proteobacteria,2USJX@28211|Alphaproteobacteria 28211|Alphaproteobacteria G cellulose 1,4-beta-cellobiosidase activity - - - - - - - - - - - - - k59_242665_1 1144664.F973_01707 2.34e-20 103.0 COG1040@1|root,COG1040@2|Bacteria,1QV41@1224|Proteobacteria,1RSAP@1236|Gammaproteobacteria,3NM26@468|Moraxellaceae 1236|Gammaproteobacteria K acetyltransferase - - - - - - - - - - - - - k59_120859_1 105154.Q9MBU6_9VIRU 1.28e-117 354.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_48577_1 931626.Awo_c24810 1.11e-20 94.0 COG0535@1|root,COG0535@2|Bacteria,1V348@1239|Firmicutes,24GVU@186801|Clostridia,25X0M@186806|Eubacteriaceae 186801|Clostridia C Radical SAM superfamily - - - - - - - - - - - - Fer4_12,Radical_SAM,SPASM k59_254839_1 1128073.G9LQV6_9CIRC 3.44e-19 89.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_363715_3 161156.JQKW01000012_gene6 4.32e-09 60.5 COG0500@1|root,COG2226@2|Bacteria,2GI40@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11 k59_242671_2 1110502.TMO_0047 5.5e-12 68.9 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,2TVGJ@28211|Alphaproteobacteria,2JPR0@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_134217_15 391600.ABRU01000057_gene378 8.74e-20 89.7 COG5018@1|root,COG5018@2|Bacteria,1QVMV@1224|Proteobacteria 1224|Proteobacteria L 3' exoribonuclease, RNase T-like - - - - - - - - - - - - DUF5051 k59_134217_16 4577.GRMZM2G428964_P01 0.000162 48.9 28IQY@1|root,2QR28@2759|Eukaryota,37QGJ@33090|Viridiplantae,3GH0X@35493|Streptophyta,3KT1A@4447|Liliopsida,3I7QK@38820|Poales 35493|Streptophyta - - - - - - - - - - - - - - - k59_134217_17 1178540.BA70_16410 6.64e-15 87.4 COG3378@1|root,COG4983@1|root,COG3378@2|Bacteria,COG4983@2|Bacteria,1TQP9@1239|Firmicutes,4HBTB@91061|Bacilli,1ZEU3@1386|Bacillus 91061|Bacilli S D5 N terminal like - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,PriCT_1,Prim-Pol k59_134217_19 1403946.Q615_SPAC00127G0154 4.64e-37 141.0 28HHC@1|root,2Z7T2@2|Bacteria,1TR3B@1239|Firmicutes 1239|Firmicutes S AAA domain - - - - - - - - - - - - AAA_24 k59_134217_40 598467.BrE312_2702 4.47e-22 95.9 28RDB@1|root,2ZDSP@2|Bacteria,1RBF9@1224|Proteobacteria,1RQ0W@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - Tube k59_134220_1 105154.Q9MBU6_9VIRU 1.46e-73 238.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_134220_2 105154.Q9MBU3_9VIRU 3.84e-07 53.9 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_170704_1 441769.ABFU01000061_gene426 2.69e-24 105.0 COG1091@1|root,COG1091@2|Bacteria,1TREY@1239|Firmicutes,4HF9V@91061|Bacilli,1ZQAK@1386|Bacillus 91061|Bacilli M RmlD substrate binding domain - - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind k59_97910_3 103372.F4WEQ8 1.78e-06 52.8 2CXGH@1|root,2RX9T@2759|Eukaryota,39YTV@33154|Opisthokonta,3BMVG@33208|Metazoa,3DDBX@33213|Bilateria,42250@6656|Arthropoda,3SITN@50557|Insecta,46M7W@7399|Hymenoptera 33208|Metazoa - - - - - - - - - - - - - - Parvo_coat_N k59_256243_2 1618251.A0A0C5I2L8_9CIRC 1.28e-40 149.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_268407_6 1234888.K0A2J2_9VIRU 1.87e-129 389.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_12975_1 130081.XP_005702999.1 1.49e-05 54.7 COG1241@1|root,KOG0481@2759|Eukaryota 2759|Eukaryota L DNA replication origin binding MCM5 GO:0000003,GO:0000082,GO:0000228,GO:0000278,GO:0000280,GO:0000347,GO:0000712,GO:0000724,GO:0000725,GO:0000727,GO:0000781,GO:0000784,GO:0000785,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005656,GO:0005657,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006267,GO:0006268,GO:0006270,GO:0006275,GO:0006281,GO:0006302,GO:0006310,GO:0006323,GO:0006325,GO:0006342,GO:0006343,GO:0006348,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007049,GO:0007059,GO:0007127,GO:0007131,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010639,GO:0016043,GO:0016458,GO:0019219,GO:0019222,GO:0022402,GO:0022414,GO:0022607,GO:0030174,GO:0030261,GO:0031261,GO:0031298,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031935,GO:0031936,GO:0031938,GO:0031939,GO:0031974,GO:0031981,GO:0032392,GO:0032508,GO:0032991,GO:0032993,GO:0033043,GO:0033044,GO:0033260,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0035825,GO:0036387,GO:0036388,GO:0040029,GO:0042023,GO:0042555,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043565,GO:0043596,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0044770,GO:0044772,GO:0044786,GO:0044843,GO:0045132,GO:0045814,GO:0045815,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048285,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051052,GO:0051095,GO:0051097,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051304,GO:0051307,GO:0051321,GO:0051336,GO:0051346,GO:0051716,GO:0060255,GO:0060968,GO:0060969,GO:0061982,GO:0065003,GO:0065004,GO:0065007,GO:0065009,GO:0070013,GO:0071103,GO:0071162,GO:0071704,GO:0071824,GO:0071840,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0098687,GO:0098813,GO:0140013,GO:1901360,GO:1901363,GO:1901576,GO:1902275,GO:1902292,GO:1902299,GO:1902315,GO:1902679,GO:1902680,GO:1902969,GO:1902975,GO:1903046,GO:1903047,GO:1903506,GO:1903507,GO:1903508,GO:1905268,GO:1990837,GO:2000112,GO:2000113,GO:2001141,GO:2001251 3.6.4.12 ko:K02209,ko:K11592 ko03030,ko04110,ko04111,ko04113,ko05206,map03030,map04110,map04111,map04113,map05206 M00285 - - ko00000,ko00001,ko00002,ko01000,ko03032,ko03036 - - - MCM,MCM_N,MCM_OB k59_12975_2 665950.HMPREF1025_01456 2.22e-61 196.0 COG4725@1|root,COG4725@2|Bacteria,1TSJV@1239|Firmicutes,248X5@186801|Clostridia,27KVV@186928|unclassified Lachnospiraceae 186801|Clostridia KT MT-A70 - - - - - - - - - - - - MT-A70 k59_12975_4 1229909.NSED_08385 2.82e-14 68.6 COG1522@1|root,arCOG01117@2157|Archaea 2157|Archaea K COG1522 Transcriptional regulators - - - - - - - - - - - - AsnC_trans_reg k59_377889_1 1692259.A0A0K1RL59_9CIRC 2.93e-26 110.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_305023_2 1408254.T458_20835 1.8e-14 75.9 COG4675@1|root,COG4675@2|Bacteria,1VHKQ@1239|Firmicutes,4HVG0@91061|Bacilli,26XMT@186822|Paenibacillaceae 91061|Bacilli S Phage Tail Collar Domain mdpB - - - - - - - - - - - Collar k59_1220_4 1618236.A0A0C5I2F3_9CIRC 2.02e-23 102.0 4QGVY@10239|Viruses,4QUKN@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_49909_1 1234888.K0A2J2_9VIRU 6.03e-48 172.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_220148_2 1618254.A0A0C5IBG4_9CIRC 1.51e-152 432.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_122828_1 1288079.AUKN01000018_gene2497 8.12e-40 152.0 28NJJ@1|root,2ZBKQ@2|Bacteria,2IBUV@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - Prim-Pol k59_12998_6 7719.NP_001027608.1 1.9e-08 60.8 KOG4459@1|root,KOG4459@2759|Eukaryota,38BM6@33154|Opisthokonta,3BB3X@33208|Metazoa,3CSF3@33213|Bilateria,488RE@7711|Chordata 33208|Metazoa S procollagen-proline 3-dioxygenase activity LEPRE1 GO:0001501,GO:0001558,GO:0002791,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005576,GO:0005604,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005783,GO:0005788,GO:0005794,GO:0005886,GO:0006457,GO:0006464,GO:0006807,GO:0007275,GO:0007399,GO:0008150,GO:0008152,GO:0008285,GO:0009058,GO:0009892,GO:0009987,GO:0010605,GO:0010720,GO:0010975,GO:0010976,GO:0012505,GO:0016020,GO:0016043,GO:0016491,GO:0016705,GO:0016706,GO:0017185,GO:0018126,GO:0018193,GO:0018205,GO:0018208,GO:0019222,GO:0019511,GO:0019538,GO:0019797,GO:0019798,GO:0022008,GO:0030154,GO:0030198,GO:0030199,GO:0030278,GO:0030308,GO:0031012,GO:0031323,GO:0031324,GO:0031344,GO:0031346,GO:0031399,GO:0031400,GO:0031543,GO:0031544,GO:0031647,GO:0031974,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032963,GO:0032964,GO:0032991,GO:0036211,GO:0040008,GO:0042127,GO:0043062,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043933,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045926,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050708,GO:0050767,GO:0050769,GO:0050789,GO:0050793,GO:0050794,GO:0050821,GO:0051046,GO:0051049,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051213,GO:0051223,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051960,GO:0051962,GO:0055114,GO:0060255,GO:0060284,GO:0060348,GO:0061077,GO:0062023,GO:0065007,GO:0065008,GO:0070013,GO:0070201,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090087,GO:0097435,GO:0120035,GO:0140096,GO:1901564,GO:1901873,GO:1901874,GO:1902494,GO:1903530,GO:2000026 1.14.11.7 ko:K08134,ko:K22459,ko:K22460 - - - - ko00000,ko00535,ko01000,ko03110 - - - 2OG-FeII_Oxy_3 k59_12998_10 326442.PSHAa1556 6.88e-27 130.0 COG4733@1|root,COG4733@2|Bacteria,1R7KR@1224|Proteobacteria,1S1E5@1236|Gammaproteobacteria,2Q40F@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S Fibronectin type 3 domain - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - DUF1983,Phage-tail_3 k59_110595_2 1408438.JADD01000033_gene531 7.25e-109 348.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,4H9Z7@91061|Bacilli 91061|Bacilli L DNA polymerase - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_110595_3 525246.HMPREF0058_1677 8.94e-19 83.6 28J2E@1|root,2Z8YX@2|Bacteria,2IB5J@201174|Actinobacteria,4D4XD@85005|Actinomycetales 201174|Actinobacteria S Protein of unknown function (DUF2815) - - - - - - - - - - - - DUF2815 k59_256350_1 648757.Rvan_3315 3.6e-90 280.0 COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,3N62D@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_3,Terminase_6,Terminase_6C k59_305816_1 1562701.BBOF01000007_gene82 1.7e-09 65.1 2CHRY@1|root,30Z9E@2|Bacteria,1RGQK@1224|Proteobacteria,2W3T9@28216|Betaproteobacteria,1KAPA@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_147710_2 637389.Acaty_c0109 2.33e-18 78.6 2E7GT@1|root,331ZH@2|Bacteria,1NAHD@1224|Proteobacteria,1SIM9@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_147710_7 172088.AUGA01000043_gene4884 5.81e-33 120.0 COG2131@1|root,COG2131@2|Bacteria 2|Bacteria F dCMP deaminase activity comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_293622_3 1353537.TP2_16155 3.01e-58 200.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS19@28211|Alphaproteobacteria,2XN2A@285107|Thioclava 28211|Alphaproteobacteria F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdZ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k59_196376_1 290317.Cpha266_1627 9.05e-36 137.0 COG0582@1|root,COG0582@2|Bacteria 2|Bacteria L DNA integration - - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k59_172023_1 1609634.A0A0C5AFV4_9VIRU 9.32e-186 535.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_172023_2 1609634.A0A0C5ANA6_9VIRU 9.72e-20 88.2 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_74923_2 136084.Q9G0G8_9CAUD 2.63e-72 231.0 4QGZN@10239|Viruses,4R0FF@35237|dsDNA viruses no RNA stage,4QTUK@28883|Caudovirales,4QNE5@10744|Podoviridae 10744|Podoviridae S nuclease activity - - - - - - - - - - - - - k59_74923_3 461711.A0A096VKW7_9CAUD 2.07e-28 107.0 4QASP@10239|Viruses,4QVR8@35237|dsDNA viruses no RNA stage,4QR4Z@28883|Caudovirales,4QNQ0@10744|Podoviridae 10744|Podoviridae S deoxyribonuclease IV (phage-T4-induced) activity - - - - - - - - - - - - - k59_366205_3 316274.Haur_1369 1.03e-11 67.8 COG4372@1|root,COG5283@1|root,COG5412@1|root,COG4372@2|Bacteria,COG5283@2|Bacteria,COG5412@2|Bacteria,2G9J0@200795|Chloroflexi 2|Bacteria M TIGRFAM phage tail tape measure protein, TP901 family Z012_10445 - - ko:K01991,ko:K07161,ko:K07484 ko02026,map02026 - - - ko00000,ko00001,ko02000 1.B.18 - - DDE_Tnp_IS66,DUF3084,LZ_Tnp_IS66,PhageMin_Tail,zf-IS66 k59_160037_3 1429046.RR21198_4856 2.75e-12 69.3 2C9JF@1|root,32RPD@2|Bacteria,2GS69@201174|Actinobacteria,4G5U3@85025|Nocardiaceae 201174|Actinobacteria S ERF superfamily - - - - - - - - - - - - ERF k59_244652_2 1618251.A0A0C5I2L8_9CIRC 3.1e-59 199.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_86922_3 1609634.A0A0C5AFV4_9VIRU 8.66e-44 156.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_50562_3 459349.CLOAM0416 9.32e-13 77.4 COG0463@1|root,COG0463@2|Bacteria,2NPA5@2323|unclassified Bacteria 2|Bacteria M Glycosyl transferase family 2 kdtX - - ko:K12984 - - - - ko00000,ko01000,ko01003,ko01005,ko02000 4.D.1.3 GT2 - Glycos_transf_2 k59_354457_1 1005048.CFU_3365 1.28e-20 94.7 COG4653@1|root,COG4653@2|Bacteria,1MYMH@1224|Proteobacteria,2VNUG@28216|Betaproteobacteria 28216|Betaproteobacteria S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_354457_2 1129146.H2BDB2_9CAUD 5.84e-17 77.4 4QEAQ@10239|Viruses,4QVWS@35237|dsDNA viruses no RNA stage,4QQWE@28883|Caudovirales,4QMGH@10699|Siphoviridae 10699|Siphoviridae S transferase activity, transferring glycosyl groups - - - - - - - - - - - - - k59_282045_1 3218.PP1S77_291V6.1 3.72e-15 76.6 COG0216@1|root,KOG2726@2759|Eukaryota,37SSY@33090|Viridiplantae,3G9BB@35493|Streptophyta 35493|Streptophyta J peptide chain release factor - - - - - - - - - - - - RF-1 k59_172029_1 283942.IL0025 5.47e-06 53.9 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,2QFWD@267893|Idiomarinaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_232716_2 1692249.A0A0K1RLN8_9CIRC 2.88e-13 70.5 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_196532_1 225400.XP_006752859.1 5.35e-32 123.0 COG1089@1|root,KOG1372@2759|Eukaryota,38I66@33154|Opisthokonta,3B9EK@33208|Metazoa,3CRXA@33213|Bilateria,481RW@7711|Chordata,48YAP@7742|Vertebrata,3J5M7@40674|Mammalia,4KQ42@9397|Chiroptera 33208|Metazoa G GDP-mannose 4,6 dehydratase GMDS GO:0000003,GO:0000166,GO:0003006,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0007154,GO:0007165,GO:0007166,GO:0007219,GO:0007276,GO:0007281,GO:0007292,GO:0008150,GO:0008152,GO:0008446,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019673,GO:0019953,GO:0022412,GO:0022414,GO:0023052,GO:0030154,GO:0032501,GO:0032502,GO:0032504,GO:0034641,GO:0034654,GO:0036094,GO:0042350,GO:0042351,GO:0042802,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0046368,GO:0046483,GO:0048037,GO:0048468,GO:0048477,GO:0048609,GO:0048856,GO:0048869,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051302,GO:0051704,GO:0051716,GO:0055086,GO:0065007,GO:0070401,GO:0071704,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2000035 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd k59_196532_2 1121033.AUCF01000009_gene1201 1.86e-45 156.0 COG1442@1|root,COG1442@2|Bacteria,1QH4S@1224|Proteobacteria,2U2NZ@28211|Alphaproteobacteria,2JTII@204441|Rhodospirillales 204441|Rhodospirillales M glycosyl transferase family 8 - - - - - - - - - - - - - k59_13955_1 642492.Clole_1831 3.43e-20 91.7 COG1846@1|root,COG3935@1|root,COG1846@2|Bacteria,COG3935@2|Bacteria,1VHK1@1239|Firmicutes,24RG5@186801|Clostridia 186801|Clostridia L Helix-turn-helix domain - - - - - - - - - - - - HTH_36 k59_111847_1 429009.Adeg_1542 3.39e-11 65.1 COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia,42GIM@68295|Thermoanaerobacterales 186801|Clostridia D Maf-like protein maf - - ko:K06287 - - - - ko00000 - - - Maf k59_221610_4 1609634.A0A0C5AFT2_9VIRU 6.65e-101 303.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_13958_1 1435356.Y013_10015 1.5e-08 61.6 COG0464@1|root,COG1222@1|root,COG0464@2|Bacteria,COG1222@2|Bacteria,2GJNW@201174|Actinobacteria,4FUDN@85025|Nocardiaceae 201174|Actinobacteria O Belongs to the AAA ATPase family - - - ko:K13525 ko04141,ko05134,map04141,map05134 M00400,M00403 - - ko00000,ko00001,ko00002,ko03019,ko04131,ko04147 3.A.16.1 - - AAA,CDC48_N k59_282877_1 1347393.HG726020_gene1834 2e-05 57.0 COG0454@1|root,COG0553@1|root,COG0827@1|root,COG0456@2|Bacteria,COG0553@2|Bacteria,COG0827@2|Bacteria,4NZK9@976|Bacteroidetes,2FRRF@200643|Bacteroidia,4APRR@815|Bacteroidaceae 976|Bacteroidetes KL CRISPR-associated helicase, Cas3 - - - - - - - - - - - - - k59_148193_4 1147144.K7P6W0_9CAUD 4.73e-28 106.0 4QB0C@10239|Viruses,4QW7S@35237|dsDNA viruses no RNA stage,4QPK3@28883|Caudovirales,4QKQC@10699|Siphoviridae 10699|Siphoviridae S magnesium ion binding - - - - - - - - - - - - - k59_160674_1 1197719.A464_1008 2.14e-06 58.9 COG1196@1|root,COG5281@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5281@2|Bacteria,COG5283@2|Bacteria,1MU81@1224|Proteobacteria,1RS6P@1236|Gammaproteobacteria,3ZND5@590|Salmonella 1236|Gammaproteobacteria D tail length tape measure ynaA - - - - - - - - - - - TMP_2,Tape_meas_lam_C k59_318868_2 1788447.A0A190WHJ9_9CIRC 8.07e-83 258.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_172708_3 402777.KB235904_gene4777 1.53e-10 61.6 COG4886@1|root,COG4886@2|Bacteria,1G0NZ@1117|Cyanobacteria,1HA8J@1150|Oscillatoriales 1117|Cyanobacteria S Leucine-rich repeat (LRR) protein - - - - - - - - - - - - - k59_330930_11 1449069.JMLO01000001_gene1579 5.01e-16 77.4 2CICW@1|root,346YY@2|Bacteria,2HIJU@201174|Actinobacteria,4G48K@85025|Nocardiaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_197097_2 1634476.A0A0F6TGK2_9CIRC 1.69e-31 125.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_2636_1 134676.ACPL_1143 5.07e-08 60.8 COG5519@1|root,COG5519@2|Bacteria,2I2ST@201174|Actinobacteria,4DIQ5@85008|Micromonosporales 201174|Actinobacteria L Bifunctional DNA primase/polymerase, N-terminal - - - - - - - - - - - - Prim-Pol k59_51176_1 1692256.A0A0K1RL85_9CIRC 7.7e-32 122.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_233422_1 99598.Cal7507_5665 8.23e-07 58.5 COG4870@1|root,COG4870@2|Bacteria,1G85R@1117|Cyanobacteria,1HNEI@1161|Nostocales 1117|Cyanobacteria O PFAM Papain family cysteine protease - - - - - - - - - - - - Peptidase_C1 k59_355539_1 1209072.ALBT01000003_gene703 7.37e-65 213.0 COG0582@1|root,COG0582@2|Bacteria,1QWI5@1224|Proteobacteria,1T2VS@1236|Gammaproteobacteria 1236|Gammaproteobacteria L viral genome integration into host DNA - - - - - - - - - - - - - k59_355539_3 202954.BBNK01000034_gene3794 1.31e-47 155.0 2A3Q7@1|root,30S7S@2|Bacteria,1NP2K@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_355539_6 1395516.PMO01_05160 4.41e-73 233.0 COG2404@1|root,COG2404@2|Bacteria,1MXEH@1224|Proteobacteria,1SADM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S phosphoesterase DHHA1 - - - - - - - - - - - - DHHA1 k59_355539_7 1122917.KB899685_gene3237 1.34e-94 290.0 COG4422@1|root,COG4422@2|Bacteria,1TPP1@1239|Firmicutes,4HAU8@91061|Bacilli,26V16@186822|Paenibacillaceae 91061|Bacilli S Protein of unknown function (DUF5131) - - - - - - - - - - - - DUF5131 k59_258329_1 1609634.A0A0C5AFT2_9VIRU 2.68e-14 76.6 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_246031_2 1206737.BAGF01000007_gene476 6.92e-80 259.0 COG1396@1|root,COG1396@2|Bacteria,2IAPZ@201174|Actinobacteria,4FZUC@85025|Nocardiaceae 201174|Actinobacteria K sequence-specific DNA binding - - - - - - - - - - - - HTH_31 k59_283738_1 445972.ANACOL_01831 8.09e-15 70.9 2ADP3@1|root,313E1@2|Bacteria,1W6J2@1239|Firmicutes,2572T@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_283738_6 1123508.JH636446_gene6139 1.36e-15 75.1 2DRCN@1|root,33B89@2|Bacteria,2J3XX@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_294905_1 234621.RER_07200 8.4e-98 322.0 COG1572@1|root,COG1572@2|Bacteria,2GJ8Y@201174|Actinobacteria 201174|Actinobacteria S Glycosyl hydrolase family 71 - - - - - - - - - - - - Glyco_hydro_71 k59_64293_3 1237500.ANBA01000041_gene4434 1.62e-23 104.0 COG3409@1|root,COG3409@2|Bacteria,2IAGF@201174|Actinobacteria,4EQXV@85012|Streptosporangiales 201174|Actinobacteria M N-acetylmuramoyl-L-alanine amidase - - - ko:K01446 - - R04112 RC00064,RC00141 ko00000 - - - Amidase_2,PG_binding_1 k59_76060_1 439235.Dalk_4546 2.66e-07 63.2 COG3266@1|root,COG3266@2|Bacteria 2|Bacteria GM domain, Protein - - - ko:K03112 - - - - ko00000 - - - SPOR,YARHG k59_283742_1 760142.Hipma_1328 8.47e-05 50.4 COG0457@1|root,COG0457@2|Bacteria,1PFUI@1224|Proteobacteria,42W2K@68525|delta/epsilon subdivisions,2WRN3@28221|Deltaproteobacteria,2M7CH@213113|Desulfurellales 28221|Deltaproteobacteria S TPR repeat - - - - - - - - - - - - TPR_1,TPR_19,TPR_8 k59_14521_1 1121904.ARBP01000023_gene5016 1.42e-21 107.0 COG2730@1|root,COG5492@1|root,COG2730@2|Bacteria,COG5492@2|Bacteria 2|Bacteria N domain, Protein - - 3.2.1.4 ko:K01179,ko:K03932 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - CE1,GH5,GH9 - Big_2,Cellulase,Flg_new,SLH k59_331699_2 1379725.S5TMY9_9CIRC 1.57e-54 190.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_136734_2 1520935.A0A0H3UB63_9CIRC 5.9e-38 142.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_161378_2 1121874.KB892377_gene1408 1.37e-05 53.9 COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,3VQGY@526524|Erysipelotrichia 526524|Erysipelotrichia L Primosomal protein DnaI - - - ko:K11144 - - - - ko00000,ko03032 - - - DnaI_N,IstB_IS21 k59_161378_4 1500281.JQKZ01000020_gene3225 8.21e-13 70.1 COG3409@1|root,COG3409@2|Bacteria,4PPJM@976|Bacteroidetes,1IKP5@117743|Flavobacteriia,3ZUK3@59732|Chryseobacterium 976|Bacteroidetes M D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Peptidase_M15_4 k59_3494_1 145579.CAPSD_BPPHM 9.38e-60 211.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_64966_3 557598.LHK_01542 3.08e-136 397.0 28HXV@1|root,2Z83C@2|Bacteria,1PJBP@1224|Proteobacteria,2VZV5@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_64966_6 1121434.AULY01000011_gene1829 2.85e-30 130.0 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,42YKK@68525|delta/epsilon subdivisions,2WUDS@28221|Deltaproteobacteria,2M8E7@213115|Desulfovibrionales 28221|Deltaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_198244_1 469610.HMPREF0189_01108 6.73e-46 174.0 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,2VU8A@28216|Betaproteobacteria 28216|Betaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_162038_1 1540097.A0A0A0YRN0_9CAUD 2.03e-49 177.0 4QF3C@10239|Viruses,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_234732_2 1079460.ATTQ01000012_gene2499 5.61e-08 53.9 COG1442@1|root,COG1442@2|Bacteria,1QH4S@1224|Proteobacteria,2U9KQ@28211|Alphaproteobacteria,4B9U9@82115|Rhizobiaceae 28211|Alphaproteobacteria M glycosyl transferase family 8 - - - - - - - - - - - - - k59_113120_2 291607.REP2_SCSVF 5.18e-29 118.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_76790_1 1336243.JAEA01000002_gene2664 2.74e-100 322.0 COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria,2U1JR@28211|Alphaproteobacteria 28211|Alphaproteobacteria K DNA-dependent RNA polymerase - - - - - - - - - - - - RNA_pol,RPOL_N k59_64967_3 1111131.HMPREF1255_1460 1.41e-62 217.0 COG4626@1|root,COG4626@2|Bacteria,2GM6F@201174|Actinobacteria 201174|Actinobacteria L phage terminase - - - - - - - - - - - - Terminase_1 k59_125743_1 675817.VDA_000908 1.9e-35 142.0 COG0454@1|root,COG0503@1|root,COG1040@1|root,COG0456@2|Bacteria,COG0503@2|Bacteria,COG1040@2|Bacteria,1QV41@1224|Proteobacteria,1RSAP@1236|Gammaproteobacteria,1XVT9@135623|Vibrionales 135623|Vibrionales K acetyltransferase - - - - - - - - - - - - - k59_184866_2 1408415.JHXL01000001_gene388 1.72e-73 249.0 COG4626@1|root,COG4626@2|Bacteria,3WU1D@544448|Tenericutes 544448|Tenericutes S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_380558_2 1519439.JPJG01000059_gene1913 3.16e-05 45.1 2CHCE@1|root,32Z7E@2|Bacteria,1VIXB@1239|Firmicutes,24TNE@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_125748_1 1207063.P24_17192 1.07e-35 132.0 COG4653@1|root,COG4653@2|Bacteria,1MWU1@1224|Proteobacteria,2TSSY@28211|Alphaproteobacteria,2JVTQ@204441|Rhodospirillales 204441|Rhodospirillales S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_223022_3 691965.D4P7D6_9CAUD 5.36e-95 312.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_271095_1 1415147.V5Q8T2_9CAUD 7.59e-13 71.2 4QDKG@10239|Viruses,4QV7J@35237|dsDNA viruses no RNA stage,4QREF@28883|Caudovirales,4QMWU@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_344073_1 105154.Q9MBU6_9VIRU 1.82e-66 221.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_246917_2 1609634.A0A0C5ANA6_9VIRU 2.58e-17 86.3 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_234824_1 1986029.Q9MBM8_9VIRU 1.48e-59 201.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_199007_1 1283078.M1IPN0_9CAUD 4.69e-60 198.0 4QHD0@10239|Viruses,4QXZW@35237|dsDNA viruses no RNA stage,4QUGC@28883|Caudovirales,4QP48@10744|Podoviridae 10744|Podoviridae S T=7 icosahedral viral capsid - - - - - - - - - - - - - k59_271777_2 1121935.AQXX01000130_gene2425 4.82e-44 147.0 2AD08@1|root,312N7@2|Bacteria,1NDC4@1224|Proteobacteria,1SAPT@1236|Gammaproteobacteria,1XQHK@135619|Oceanospirillales 135619|Oceanospirillales S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_368814_1 1234888.K0A2J2_9VIRU 6.6e-49 173.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_29167_4 1449351.RISW2_21770 2.32e-14 85.5 COG1196@1|root,COG3941@1|root,COG1196@2|Bacteria,COG3941@2|Bacteria 2|Bacteria O tape measure - - - - - - - - - - - - PhageMin_Tail,TMP_2,Tape_meas_lam_C k59_344803_1 1150626.PHAMO_80072 1.3e-18 87.0 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,2TV42@28211|Alphaproteobacteria,2JXEM@204441|Rhodospirillales 204441|Rhodospirillales S Terminase-like family - - - - - - - - - - - - - k59_77492_1 366394.Smed_1815 6.56e-26 108.0 COG3266@1|root,COG3266@2|Bacteria,1QZ8S@1224|Proteobacteria,2URTR@28211|Alphaproteobacteria 28211|Alphaproteobacteria M lytic transglycosylase activity - - - - - - - - - - - - - k59_356816_13 323098.Nwi_1615 0.000136 54.3 COG1511@1|root,COG5281@1|root,COG1511@2|Bacteria,COG5281@2|Bacteria,1MX2R@1224|Proteobacteria,2U3WK@28211|Alphaproteobacteria,3K1A2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S tape measure protein - - - - - - - - - - - - Peptidase_M15_4,Tape_meas_lam_C k59_296402_1 1618248.A0A0C5IB82_9CIRC 3.51e-24 100.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_223813_1 1217705.F900_02100 1.56e-07 59.7 COG3209@1|root,COG3209@2|Bacteria,1QQQ8@1224|Proteobacteria,1RTCI@1236|Gammaproteobacteria,3NSJ8@468|Moraxellaceae 1236|Gammaproteobacteria M Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - Laminin_G_3 k59_321034_3 269796.Rru_A3313 1.37e-31 122.0 28IR7@1|root,2Z8QR@2|Bacteria,1PBTP@1224|Proteobacteria,2U248@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_211887_3 1788447.A0A190WHJ9_9CIRC 1.75e-90 275.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_235450_1 1121405.dsmv_0748 4.55e-10 67.0 COG2133@1|root,COG3637@1|root,COG4733@1|root,COG2133@2|Bacteria,COG3637@2|Bacteria,COG4733@2|Bacteria,1R2HQ@1224|Proteobacteria,42ZN7@68525|delta/epsilon subdivisions,2WUV4@28221|Deltaproteobacteria 28221|Deltaproteobacteria GM PFAM Di-glucose binding within endoplasmic reticulum - - - - - - - - - - - - Malectin k59_15946_1 759938.F5BSB4_9CIRC 2.67e-19 88.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_15946_3 1618242.A0A0C5IBR9_9CIRC 3e-19 90.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_16621_2 1692255.A0A0K1RL52_9CIRC 3.85e-30 122.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_224608_2 658172.CKC_03515 2.48e-19 94.4 290X3@1|root,2ZNIW@2|Bacteria,1P7TA@1224|Proteobacteria,2UXFQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_151326_1 1500301.JQMF01000006_gene1755 4.26e-97 305.0 28MSK@1|root,2ZB0X@2|Bacteria,1R7CY@1224|Proteobacteria,2U2MY@28211|Alphaproteobacteria,4BJ92@82115|Rhizobiaceae 28211|Alphaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_321753_1 1122981.AUME01000026_gene555 3.83e-11 66.6 COG4712@1|root,COG4712@2|Bacteria,4NNWK@976|Bacteroidetes,2FR2J@200643|Bacteroidia 976|Bacteroidetes S double-strand break repair protein - - - - - - - - - - - - Rad52_Rad22 k59_175856_1 1122179.KB890497_gene2795 7.59e-33 137.0 COG0210@1|root,COG0210@2|Bacteria,4NJNQ@976|Bacteroidetes,1IYS8@117747|Sphingobacteriia 976|Bacteroidetes L UvrD-like helicase C-terminal domain - - - - - - - - - - - - AAA_19,UvrD-helicase,UvrD_C k59_30124_1 202752.JL53_00730 1.03e-29 120.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H9YP@91061|Bacilli,26MKQ@186820|Listeriaceae 91061|Bacilli L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_212701_1 283699.D172_4039 3.12e-23 94.7 COG3772@1|root,COG3772@2|Bacteria,1N0ZQ@1224|Proteobacteria,1S9AE@1236|Gammaproteobacteria,2Q38I@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_309412_11 1089544.KB912942_gene6362 1.21e-22 99.0 2BWS4@1|root,32XQ0@2|Bacteria,2GZ9I@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_369564_2 1288494.EBAPG3_19180 3.26e-21 97.4 291GM@1|root,2ZP3A@2|Bacteria,1RD1E@1224|Proteobacteria,2VRS0@28216|Betaproteobacteria,372PP@32003|Nitrosomonadales 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_90847_2 1165094.RINTHH_3920 3.22e-37 140.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_139138_2 187303.BN69_2086 2.3e-96 295.0 COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2TT5T@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB - 4.2.1.46,4.2.1.76,5.1.3.2 ko:K01710,ko:K01784,ko:K12450 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 M00361,M00362,M00632,M00793 R00291,R00293,R02984,R06513 RC00289,RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd k59_139138_4 316055.RPE_1506 2.01e-44 152.0 COG0279@1|root,COG0279@2|Bacteria,1PW0E@1224|Proteobacteria,2U850@28211|Alphaproteobacteria 28211|Alphaproteobacteria G SIS domain - - 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 - - - SIS_2 k59_139138_5 316055.RPE_1508 1.3e-35 129.0 COG0176@1|root,COG0176@2|Bacteria,1QAUK@1224|Proteobacteria 1224|Proteobacteria H Transaldolase tal - 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA k59_78411_2 1234888.K0A2J2_9VIRU 9.42e-78 259.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_78411_4 145579.REP_BPPHM 3.93e-19 93.2 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_91863_1 1028801.RG1141_CH01630 2.91e-37 144.0 COG4653@1|root,COG4653@2|Bacteria,1MXMN@1224|Proteobacteria,2U062@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_225496_1 521674.Plim_4251 6e-31 130.0 COG4695@1|root,COG4695@2|Bacteria,2IZS2@203682|Planctomycetes 203682|Planctomycetes S Phage portal protein - - - - - - - - - - - - Phage_portal k59_30907_1 348824.LPU83_0595 2.02e-101 316.0 COG3740@1|root,COG3740@2|Bacteria,1QVIJ@1224|Proteobacteria,2TVIM@28211|Alphaproteobacteria,4BNVZ@82115|Rhizobiaceae 28211|Alphaproteobacteria S Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_176770_1 1408428.JNJP01000007_gene1930 2.99e-05 51.2 COG0582@1|root,COG0582@2|Bacteria,1MVZB@1224|Proteobacteria,42M9T@68525|delta/epsilon subdivisions,2WNVF@28221|Deltaproteobacteria,2M8MI@213115|Desulfovibrionales 28221|Deltaproteobacteria L Belongs to the 'phage' integrase family - - - ko:K03733 - - - - ko00000,ko03036 - - - Phage_integrase k59_213635_2 414996.IL38_15065 1.45e-06 52.4 COG0553@1|root,COG0553@2|Bacteria,2GISC@201174|Actinobacteria,40A97@622450|Actinopolysporales 201174|Actinobacteria L SNF2 family N-terminal domain - - - - - - - - - - - - HHH_5,Helicase_C,SNF2_N k59_287630_2 63737.Npun_F0675 0.000583 43.5 COG4627@1|root,COG4627@2|Bacteria,1G57B@1117|Cyanobacteria,1HSAU@1161|Nostocales 1117|Cyanobacteria H Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 k59_128229_2 1379725.S5TMY9_9CIRC 9.46e-38 144.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_347623_1 1121468.AUBR01000029_gene1546 8.48e-34 134.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,42G6T@68295|Thermoanaerobacterales 186801|Clostridia KL SMART DEAD-like helicase - - 2.7.11.1 ko:K08282 - - - - ko00000,ko01000 - - - Helicase_C,SNF2_N,SNF2_assoc,SWIM k59_31883_2 428125.CLOLEP_01424 2.6e-36 148.0 28K55@1|root,2Z9TX@2|Bacteria,1V0P7@1239|Firmicutes,24DCX@186801|Clostridia,3WK99@541000|Ruminococcaceae 186801|Clostridia S Psort location Cytoplasmic, score 7.50 - - - - - - - - - - - - Sipho_Gp37 k59_7382_1 1217705.F900_01843 4.19e-24 108.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,1S0Q1@1236|Gammaproteobacteria,3NQUM@468|Moraxellaceae 1236|Gammaproteobacteria L DNA polymerase family A - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_262101_1 988656.F0V6Y5_9CAUD 6.48e-07 50.4 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_18342_1 1169152.AXVD01000020_gene352 2.69e-46 166.0 2ANQ2@1|root,31ZTR@2|Bacteria,2H2QF@201174|Actinobacteria,4G8YS@85025|Nocardiaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_262102_1 1122135.KB893135_gene619 4.17e-54 185.0 COG0507@1|root,COG0507@2|Bacteria,1R1AT@1224|Proteobacteria,2U1ZX@28211|Alphaproteobacteria 28211|Alphaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - - - - - - - - - - Terminase_6 k59_55922_1 497965.Cyan7822_2247 2.28e-50 172.0 COG5549@1|root,COG5549@2|Bacteria,1GBTV@1117|Cyanobacteria 1117|Cyanobacteria O Astacin (Peptidase family M12A) - - - - - - - - - - - - - k59_201828_1 1052673.G1FGI0_9CAUD 1.38e-13 72.0 4QH06@10239|Viruses,4QYN7@35237|dsDNA viruses no RNA stage,4QPTF@28883|Caudovirales,4QM5S@10699|Siphoviridae 10699|Siphoviridae S nucleoside metabolic process - - - - - - - - - - - - - k59_201828_2 1121897.AUGO01000001_gene1411 1.8e-80 256.0 COG1488@1|root,COG1488@2|Bacteria,4NGVU@976|Bacteroidetes,1HZEQ@117743|Flavobacteriia,2NUVW@237|Flavobacterium 976|Bacteroidetes H nicotinate phosphoribosyltransferase nadV - 2.4.2.12 ko:K03462 ko00760,ko01100,ko04621,map00760,map01100,map04621 - R01271 RC00033 ko00000,ko00001,ko01000 - - - NAPRTase k59_43716_1 1385658.U5KPZ6_9VIRU 2.83e-84 271.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_68463_2 330395.Q30L55_9CAUD 2.77e-27 119.0 4QAR1@10239|Viruses,4QUNA@35237|dsDNA viruses no RNA stage,4QPJE@28883|Caudovirales,4QJ64@10662|Myoviridae 10662|Myoviridae S ATPase activity - - - - - - - - - - - - - k59_299525_3 268407.PWYN_00725 4.34e-13 75.1 COG1216@1|root,COG1216@2|Bacteria,1V5TD@1239|Firmicutes,4IPP5@91061|Bacilli,2761C@186822|Paenibacillaceae 91061|Bacilli S glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k59_43717_2 1266925.JHVX01000006_gene2063 1.04e-21 97.4 COG5511@1|root,COG5511@2|Bacteria,1MVN4@1224|Proteobacteria,2VKKT@28216|Betaproteobacteria 28216|Betaproteobacteria S Phage portal protein, lambda family - - - - - - - - - - - - Phage_portal_2 k59_226721_1 1122182.KB903813_gene2447 8.86e-12 66.6 COG1573@1|root,COG1573@2|Bacteria,2GMPT@201174|Actinobacteria,4DA7F@85008|Micromonosporales 201174|Actinobacteria L Uracil-DNA glycosylase - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_179164_1 1385658.U5KPZ6_9VIRU 5.41e-109 337.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_69537_4 1219035.NT2_13_00580 2.45e-72 238.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_372621_1 1120970.AUBZ01000070_gene1594 1.3e-12 69.3 2CEG2@1|root,2ZCEX@2|Bacteria,1RB74@1224|Proteobacteria,1S2JC@1236|Gammaproteobacteria,46AFF@72275|Alteromonadaceae 1236|Gammaproteobacteria S Phage replication protein CRI - - - - - - - - - - - - Phage_CRI,Phage_X k59_275765_2 1609634.A0A0C5AFV4_9VIRU 1.46e-128 387.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_300790_1 1158050.KB895461_gene2908 1.25e-13 75.9 COG1749@1|root,COG2372@1|root,COG2374@1|root,COG1749@2|Bacteria,COG2372@2|Bacteria,COG2374@2|Bacteria,2I2X3@201174|Actinobacteria 201174|Actinobacteria N Domain of unknown function (DUF4082) - - - - - - - - - - - - Big_5,DUF4082,Mo-co_dimer,fn3 k59_154746_1 1609634.A0A0C5AFV4_9VIRU 6.87e-76 244.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_8448_1 480808.A8W9Z5_9CAUD 5.41e-10 67.0 4QBNM@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPUI@28883|Caudovirales,4QKV6@10699|Siphoviridae 10699|Siphoviridae S Clp protease - - - - - - - - - - - - - k59_130428_1 439375.Oant_0230 1.54e-92 282.0 COG0270@1|root,COG0270@2|Bacteria,1R5MR@1224|Proteobacteria,2U53Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_215950_1 759914.BP951000_1469 3.75e-63 224.0 COG5283@1|root,COG5283@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - PhageMin_Tail k59_300798_2 1291050.JAGE01000001_gene457 1.22e-08 57.0 2E4UU@1|root,32ZP7@2|Bacteria,1VEZP@1239|Firmicutes,25DUN@186801|Clostridia 186801|Clostridia S Bacteriophage lambda head decoration protein D - - - - - - - - - - - - HDPD k59_312445_2 397288.C806_03002 1.79e-08 57.8 COG3935@1|root,COG3935@2|Bacteria,1TQ65@1239|Firmicutes,249Q8@186801|Clostridia,27JFZ@186928|unclassified Lachnospiraceae 186801|Clostridia L N-terminal phage replisome organiser (Phage_rep_org_N) - - - - - - - - - - - - DnaB_2,Phage_rep_org_N k59_130514_1 1406840.Q763_16750 0.000292 49.7 COG5492@1|root,COG5492@2|Bacteria,4NT99@976|Bacteroidetes,1I25B@117743|Flavobacteriia,2NUT5@237|Flavobacterium 976|Bacteroidetes N Bacterial Ig-like domain 2 - - - - - - - - - - - - Beta_helix,Big_2,CBM9_1,DM13,DUF4979,Pectate_lyase_3 k59_33291_1 1692244.A0A0K1RLR5_9CIRC 3.07e-11 62.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_372681_1 1234888.K0A2J2_9VIRU 1.86e-81 261.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_338029_1 1609634.A0A0C5AFT2_9VIRU 1.85e-99 302.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_338029_3 1609634.A0A0C5AFV4_9VIRU 2.37e-87 277.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_106596_2 145579.CAPSD_BPPHM 8.42e-96 299.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_70510_4 428125.CLOLEP_01425 1.11e-29 127.0 292XD@1|root,2ZQEV@2|Bacteria,1V48I@1239|Firmicutes,24GZD@186801|Clostridia,3WNVV@541000|Ruminococcaceae 186801|Clostridia S COG NOG18825 non supervised orthologous group - - - - - - - - - - - - - k59_252411_1 1117943.SFHH103_00131 2.05e-24 104.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,2U1P9@28211|Alphaproteobacteria,4BDQ9@82115|Rhizobiaceae 28211|Alphaproteobacteria S DNA packaging protein gp2 - - - - - - - - - - - - Terminase_6,Terminase_6C k59_9285_1 1234888.K0A2J2_9VIRU 3.58e-81 266.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_204096_1 1234888.K0A2J2_9VIRU 1.19e-86 282.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_188771_2 1234888.K0A2J2_9VIRU 5.07e-86 273.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_326209_1 1126411.I1TEL3_9CIRC 9.96e-25 104.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_217284_1 1385658.U5KPZ6_9VIRU 1.21e-90 285.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_180413_1 742733.HMPREF9469_05035 4.71e-19 90.5 2DHA9@1|root,32U8X@2|Bacteria,1VD44@1239|Firmicutes,24NC3@186801|Clostridia,222SC@1506553|Lachnoclostridium 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - - k59_290729_6 118163.Ple7327_0190 7.29e-07 56.6 COG2202@1|root,COG3829@1|root,COG4251@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,1G0A1@1117|Cyanobacteria,3VHNF@52604|Pleurocapsales 1117|Cyanobacteria T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9 k59_291609_3 1057002.KB905370_gene2867 1.55e-60 202.0 COG0330@1|root,COG0330@2|Bacteria,1N5JY@1224|Proteobacteria,2TUCR@28211|Alphaproteobacteria,4BAPA@82115|Rhizobiaceae 28211|Alphaproteobacteria O prohibitin homologues - - - - - - - - - - - - Band_7 k59_303052_4 1219035.NT2_13_00600 6.77e-39 144.0 290X3@1|root,2ZNIW@2|Bacteria,1P7TA@1224|Proteobacteria,2UXFQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_83889_2 1618248.A0A0C5IB82_9CIRC 3.7e-15 82.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_241269_1 1123401.JHYQ01000003_gene2190 6.7e-12 68.6 COG0741@1|root,COG2911@1|root,COG0741@2|Bacteria,COG2911@2|Bacteria,1N9K5@1224|Proteobacteria,1SE7W@1236|Gammaproteobacteria 1236|Gammaproteobacteria D lytic transglycosylase activity - - - - - - - - - - - - - k59_374847_1 1692244.A0A0K1RLR5_9CIRC 7.65e-31 116.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_314649_3 697281.Mahau_2909 9.14e-07 55.8 2CK39@1|root,32SBG@2|Bacteria,1V8KG@1239|Firmicutes,249UQ@186801|Clostridia,42IH0@68295|Thermoanaerobacterales 186801|Clostridia S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 k59_327274_3 1219035.NT2_13_00580 2.54e-103 314.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_339425_3 1609634.A0A0C5ANA6_9VIRU 5.4e-18 86.3 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_194504_2 1122201.AUAZ01000017_gene2950 4.53e-83 263.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,1RY1X@1236|Gammaproteobacteria,46BED@72275|Alteromonadaceae 1236|Gammaproteobacteria S associated with various cellular activities - - - - - - - - - - - - AAA,AAA_5 k59_170201_2 1692252.A0A0K1RL35_9CIRC 2.65e-31 127.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_24371_2 948071.S4S2L2_9CAUD 1.16e-11 71.2 4QHQ5@10239|Viruses,4QR7K@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_291685_2 1121121.KB894304_gene3341 2.43e-28 108.0 2CA0E@1|root,349DP@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_218831_4 1340709.S5WCQ6_9CAUD 2.33e-43 148.0 4QF2I@10239|Viruses,4QZUC@35237|dsDNA viruses no RNA stage,4QTZV@28883|Caudovirales,4QMSD@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_60851_2 1150626.PHAMO_210084 3.53e-29 118.0 28N1N@1|root,2ZB7Q@2|Bacteria,1R86T@1224|Proteobacteria,2U0A6@28211|Alphaproteobacteria,2JRMI@204441|Rhodospirillales 204441|Rhodospirillales H Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_1 k59_303850_3 1121441.AUCX01000014_gene507 5.79e-15 87.4 COG5563@1|root,COG5563@2|Bacteria,1Q0JE@1224|Proteobacteria,430IH@68525|delta/epsilon subdivisions,2X0GF@28221|Deltaproteobacteria,2MD65@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_364564_3 349521.HCH_04562 2.93e-12 64.3 2BY2W@1|root,33316@2|Bacteria,1NA4T@1224|Proteobacteria,1SE5U@1236|Gammaproteobacteria,1XQIF@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k59_364564_4 526222.Desal_1848 2.26e-14 72.4 2DMPB@1|root,32SV8@2|Bacteria,1NHUE@1224|Proteobacteria,430VU@68525|delta/epsilon subdivisions,2WW0U@28221|Deltaproteobacteria,2MCJ3@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_364564_9 1121921.KB898707_gene967 2.2e-36 129.0 2CIEP@1|root,3394E@2|Bacteria,1NFVU@1224|Proteobacteria,1SCD0@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_364564_16 1121935.AQXX01000130_gene2451 7.72e-32 118.0 COG2916@1|root,COG2916@2|Bacteria,1RASP@1224|Proteobacteria,1SU1W@1236|Gammaproteobacteria 1236|Gammaproteobacteria D ftsk spoiiie - - - - - - - - - - - - - k59_364564_18 69328.PVLB_09020 1.62e-45 152.0 COG3793@1|root,COG3793@2|Bacteria,1MZYH@1224|Proteobacteria,1SUJQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria P PFAM Mo-dependent nitrogenase - - - ko:K05793 - - - - ko00000 - - - TerB k59_73039_1 2003327.CAPSD_BPCHP 1.19e-12 73.2 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_376845_1 490913.C4NTF6_9CAUD 1.19e-150 436.0 4QEFX@10239|Viruses,4QYYG@35237|dsDNA viruses no RNA stage,4QRRV@28883|Caudovirales,4QNTK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_133771_1 1788444.A0A190WHB9_9CIRC 7.42e-13 68.6 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_61752_2 1165094.RINTHH_3920 1.67e-57 190.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_340964_1 1609634.A0A0C5AFV4_9VIRU 7.54e-28 115.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_328966_2 1379695.S5SXZ1_9CIRC 7.58e-23 110.0 4QD5V@10239|Viruses 10239|Viruses S Viral coat protein (S domain) - GO:0003674,GO:0003676,GO:0003723,GO:0005198,GO:0005488,GO:0005509,GO:0005575,GO:0008289,GO:0019012,GO:0019028,GO:0019030,GO:0039617,GO:0039660,GO:0043167,GO:0043169,GO:0044423,GO:0046872,GO:0097159,GO:1901363 - - - - - - - - - - - k59_328966_5 1126411.I1TEL3_9CIRC 1.81e-30 121.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_12784_1 10752.A0MZC7_BPN4 8.05e-27 116.0 4QBY0@10239|Viruses,4QW35@35237|dsDNA viruses no RNA stage,4QQ4Q@28883|Caudovirales,4QNNN@10744|Podoviridae 10744|Podoviridae S UvrD-like helicase C-terminal domain - - - - - - - - - - - - - k59_12784_3 795359.TOPB45_0793 0.00078 51.6 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GHDG@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_304647_2 1127673.GLIP_3386 4.85e-24 97.8 2AD08@1|root,312N7@2|Bacteria,1NDC4@1224|Proteobacteria 1224|Proteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_195230_1 1379725.S5TMY9_9CIRC 1.22e-48 172.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_852_2 1120705.FG95_01139 4.18e-12 74.3 COG1216@1|root,COG1216@2|Bacteria,1R554@1224|Proteobacteria,2U3P6@28211|Alphaproteobacteria,2K9SK@204457|Sphingomonadales 204457|Sphingomonadales S Glycosyl transferase, family 2 - - - - - - - - - - - - Glyco_tranf_2_3 k59_316749_1 1122947.FR7_2541 1.61e-13 78.2 COG4675@1|root,COG4675@2|Bacteria,1UNQW@1239|Firmicutes,4H9I3@909932|Negativicutes 909932|Negativicutes S tail collar domain protein - - - - - - - - - - - - - k59_316749_4 40215.BBOS01000001_gene739 6.5e-07 52.8 2DYV8@1|root,32V63@2|Bacteria,1QNWV@1224|Proteobacteria,1ST2X@1236|Gammaproteobacteria,3NNP1@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_195235_1 765698.Mesci_3819 3.15e-51 172.0 28NGF@1|root,2ZBII@2|Bacteria,1R9KY@1224|Proteobacteria,2U1P7@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_316907_2 520999.PROVALCAL_01867 5.36e-37 128.0 COG3179@1|root,COG3179@2|Bacteria,1RE8K@1224|Proteobacteria,1S4U8@1236|Gammaproteobacteria,3Z9BP@586|Providencia 1236|Gammaproteobacteria S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Peptidase_M15_4 k59_85956_1 1636271.A0A0E3M3Z1_9CAUD 1.91e-80 255.0 4QAIK@10239|Viruses,4QPEB@28883|Caudovirales,4QKNC@10699|Siphoviridae 10699|Siphoviridae S hydrolase activity - - - - - - - - - - - - - k59_219892_2 1385658.U5KPZ6_9VIRU 1.08e-100 311.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_61908_1 1692242.A0A0K1RL37_9CIRC 1.15e-12 73.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_365266_1 266117.Rxyl_0808 6.08e-08 60.1 COG1573@1|root,COG1573@2|Bacteria,2GMPT@201174|Actinobacteria,4CQC2@84995|Rubrobacteria 84995|Rubrobacteria L TIGRFAM phage SPO1 DNA polymerase-related protein - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_365266_3 1349820.M707_02655 1.68e-27 103.0 2E5GW@1|root,3308F@2|Bacteria,2GX64@201174|Actinobacteria 201174|Actinobacteria S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_365266_4 525904.Tter_0028 6.33e-09 62.8 COG1351@1|root,COG1351@2|Bacteria,2NQ7P@2323|unclassified Bacteria 2|Bacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant thyX - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 k59_195268_1 1114964.L485_00905 1.5e-95 301.0 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,2TUXC@28211|Alphaproteobacteria,2K4Z7@204457|Sphingomonadales 204457|Sphingomonadales KL helicase superfamily c-terminal domain - - - - - - - - - - - - Helicase_C,ResIII k59_195268_2 716928.AJQT01000026_gene1833 6.83e-40 149.0 COG1074@1|root,COG1074@2|Bacteria,1PNWW@1224|Proteobacteria,2V1FZ@28211|Alphaproteobacteria,4BJ4A@82115|Rhizobiaceae 28211|Alphaproteobacteria L PDDEXK-like domain of unknown function (DUF3799) - - - - - - - - - - - - DUF3799 k59_195268_3 460265.Mnod_4233 2.04e-70 228.0 COG0468@1|root,COG0468@2|Bacteria,1PXGB@1224|Proteobacteria,2V21B@28211|Alphaproteobacteria,1JXXV@119045|Methylobacteriaceae 28211|Alphaproteobacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - - - - - - - - - - - k59_195268_10 1173264.KI913949_gene1758 9.54e-07 59.7 COG3179@1|root,COG3772@1|root,COG3179@2|Bacteria,COG3772@2|Bacteria,1G6G1@1117|Cyanobacteria,1HB21@1150|Oscillatoriales 1117|Cyanobacteria S Chitinase class I - - - - - - - - - - - - DUF4231,Glyco_hydro_19,PG_binding_1 k59_195268_13 1144310.PMI07_002360 1.76e-05 55.5 2DPZ1@1|root,3340X@2|Bacteria,1R2EE@1224|Proteobacteria,2TZIB@28211|Alphaproteobacteria,4BP2Q@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_195268_15 394.NGR_c11380 2.44e-09 68.9 29W50@1|root,30HPY@2|Bacteria,1ND2Y@1224|Proteobacteria,2UF7E@28211|Alphaproteobacteria,4BEC8@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_195268_20 69279.BG36_20840 1.72e-29 115.0 2DWRQ@1|root,341KN@2|Bacteria,1NYD8@1224|Proteobacteria,2UTQ9@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_195268_23 1211777.BN77_4169 1.66e-126 377.0 2C5GI@1|root,2Z8C1@2|Bacteria,1R8XM@1224|Proteobacteria,2TUME@28211|Alphaproteobacteria,4BJKS@82115|Rhizobiaceae 28211|Alphaproteobacteria S P22 coat protein - gene protein 5 - - - - - - - - - - - - P22_CoatProtein k59_195268_25 69279.BG36_20870 4.7e-197 578.0 COG3170@1|root,COG3170@2|Bacteria,1QVEE@1224|Proteobacteria,2TWDG@28211|Alphaproteobacteria 28211|Alphaproteobacteria NU Phage P22-like portal protein - - - - - - - - - - - - P22_portal k59_195268_27 555217.Zmob_0919 2.25e-175 504.0 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,2TV42@28211|Alphaproteobacteria,2K7D4@204457|Sphingomonadales 204457|Sphingomonadales S TIGRFAM phage terminase, large subunit, PBSX family - - - ko:K06909 - - - - ko00000 - - - Terminase_3 k59_232646_2 1380390.JIAT01000001_gene4991 2.3e-15 81.6 COG0741@1|root,COG1876@1|root,COG0741@2|Bacteria,COG1876@2|Bacteria,2I4JK@201174|Actinobacteria,4CQYM@84995|Rubrobacteria 84995|Rubrobacteria M D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - SLT,VanY k59_330214_3 502347.ESCAB7627_3371 6.73e-06 48.9 2EK42@1|root,33DUG@2|Bacteria,1NHQ1@1224|Proteobacteria,1SPJR@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_62994_2 1300005.R9RGD4_9CAUD 6.52e-22 92.0 4QB2U@10239|Viruses,4QVJC@35237|dsDNA viruses no RNA stage,4QTMH@28883|Caudovirales 28883|Caudovirales S Pfam:GTA_holin_3TM - - - - - - - - - - - - - k59_232765_5 1535287.JP74_02650 1.44e-80 252.0 COG0175@1|root,COG0175@2|Bacteria,1QZJ1@1224|Proteobacteria,2U233@28211|Alphaproteobacteria 28211|Alphaproteobacteria EH sulfate reduction - - - - - - - - - - - - - k59_232765_6 445972.ANACOL_01831 8.73e-10 62.4 2ADP3@1|root,313E1@2|Bacteria,1W6J2@1239|Firmicutes,2572T@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_196464_2 1267535.KB906767_gene153 6.31e-27 107.0 COG0463@1|root,COG0463@2|Bacteria,3Y932@57723|Acidobacteria,2JNPK@204432|Acidobacteriia 204432|Acidobacteriia M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k59_208885_3 1609634.A0A0C5AFV4_9VIRU 4.77e-178 520.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_282114_1 478741.JAFS01000002_gene991 1.89e-17 82.4 COG3465@1|root,COG3465@2|Bacteria 2|Bacteria - - - - 2.1.1.72,3.1.21.3 ko:K01154,ko:K03427,ko:K09388 - - - - ko00000,ko01000,ko02048 - - - Macro,Methylase_S k59_208889_1 1267534.KB906757_gene900 1.17e-05 51.2 COG4123@1|root,COG4123@2|Bacteria 2|Bacteria AJ Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - - - - - - - - - - Methyltransf_21 k59_342143_2 1423724.BAMM01000004_gene688 1.16e-08 55.5 COG1694@1|root,COG1694@2|Bacteria,1VIQA@1239|Firmicutes,4HM6C@91061|Bacilli,3F6WJ@33958|Lactobacillaceae 91061|Bacilli S mazG nucleotide pyrophosphohydrolase - - - - - - - - - - - - MazG k59_366263_2 768706.Desor_0327 3.43e-19 90.9 COG0438@1|root,COG0438@2|Bacteria,1V2Z3@1239|Firmicutes,24BN2@186801|Clostridia,2627Y@186807|Peptococcaceae 186801|Clostridia M PFAM Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 k59_305905_5 886293.Sinac_4765 3.48e-12 71.2 COG3210@1|root,COG4733@1|root,COG3210@2|Bacteria,COG4733@2|Bacteria,2J50K@203682|Planctomycetes 203682|Planctomycetes U Pkd domain containing protein - - 2.7.11.1 ko:K12567 ko05410,ko05414,map05410,map05414 - - - ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812 - - - - k59_63002_2 32057.KB217478_gene4378 1.48e-12 72.4 COG1403@1|root,COG1403@2|Bacteria,1GI9P@1117|Cyanobacteria,1HRFK@1161|Nostocales 1117|Cyanobacteria L HNH nucleases - - - - - - - - - - - - HNH k59_147787_1 1692242.A0A0K1RKZ2_9CIRC 5.78e-48 169.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_147787_2 1692257.A0A0K1RL39_9CIRC 1.45e-74 238.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_26310_1 1430440.MGMSRv2_0497 4.65e-09 62.8 COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,2UP55@28211|Alphaproteobacteria,2JVJQ@204441|Rhodospirillales 204441|Rhodospirillales D Cellulose biosynthesis protein BcsQ - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k59_170284_1 439235.Dalk_1657 5.04e-25 105.0 COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42M4P@68525|delta/epsilon subdivisions,2WIKX@28221|Deltaproteobacteria,2MIHM@213118|Desulfobacterales 28221|Deltaproteobacteria M Polysaccharide biosynthesis protein - - - - - - - - - - - - CoA_binding_3,Polysacc_synt_2 k59_121678_1 1609634.A0A0C5AFT2_9VIRU 4.61e-80 250.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_218928_2 1101190.ARWB01000001_gene2218 3.67e-22 98.2 COG3409@1|root,COG4322@1|root,COG3409@2|Bacteria,COG4322@2|Bacteria,1R4RS@1224|Proteobacteria,2TYJ9@28211|Alphaproteobacteria 28211|Alphaproteobacteria M CHAP domain - - - - - - - - - - - - CHAP,PG_binding_1 k59_182397_1 1296990.H845_161 1.89e-18 97.4 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,2JQ4K@204441|Rhodospirillales 204441|Rhodospirillales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_231008_5 1121342.AUCO01000004_gene630 2.16e-33 137.0 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1TPHP@1239|Firmicutes,249MR@186801|Clostridia,36FKT@31979|Clostridiaceae 186801|Clostridia KL Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_364636_1 1313301.AUGC01000004_gene2286 2.78e-11 67.4 COG4122@1|root,COG4122@2|Bacteria,4P7IS@976|Bacteroidetes 976|Bacteroidetes S Methyltransferase domain - - - - - - - - - - - - Methyltransf_24 k59_328229_1 1385658.U5KPZ6_9VIRU 1.23e-199 573.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_85237_3 592029.DDD_2420 7.49e-08 55.8 COG0526@1|root,COG0526@2|Bacteria,4PDTT@976|Bacteroidetes,1IE7B@117743|Flavobacteriia,3HM2W@363408|Nonlabens 976|Bacteroidetes CO Thioredoxin - - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin k59_85237_6 1379698.RBG1_1C00001G1849 6.18e-07 51.2 COG3118@1|root,COG3118@2|Bacteria,2NPNZ@2323|unclassified Bacteria 2|Bacteria O Belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin k59_85237_8 1172188.KB911820_gene2885 4.2e-286 805.0 COG0209@1|root,COG0209@2|Bacteria,2IC1H@201174|Actinobacteria 201174|Actinobacteria F Ribonucleotide reductase, barrel domain - - - - - - - - - - - - Ribonuc_red_lgC k59_158152_1 1094496.m07a_08960 4.18e-61 207.0 28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria,2U265@28211|Alphaproteobacteria,48TXM@772|Bartonellaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_352549_1 756272.Plabr_2550 3.68e-10 65.9 COG2165@1|root,COG2165@2|Bacteria,2J1H8@203682|Planctomycetes 203682|Planctomycetes NU TIGRFAM prepilin-type N-terminal cleavage methylation domain - - - - - - - - - - - - N_methyl k59_12313_3 1692250.A0A0K1RLR1_9CIRC 4.56e-148 424.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_204_1 2003327.CAPSD_BPCHP 4.38e-120 373.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_364637_1 356851.JOAN01000016_gene6158 8.19e-05 54.7 COG2133@1|root,COG3291@1|root,COG3828@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,2GMT2@201174|Actinobacteria,4DCB0@85008|Micromonosporales 201174|Actinobacteria G Domain of Unknown Function (DUF1080) - - - - - - - - - - - - DUF1080,F5_F8_type_C,GSDH,PKD,ThuA k59_340359_1 1379715.S5TMW6_9CIRC 3.39e-11 68.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_158981_2 322855.Q52PN7_9CAUD 1.12e-99 318.0 4QBNE@10239|Viruses,4QXM4@35237|dsDNA viruses no RNA stage,4QPE9@28883|Caudovirales 28883|Caudovirales S Pfam:Carbam_trans_C - - - - - - - - - - - - - k59_268211_1 1618248.A0A0C5IB82_9CIRC 5.05e-35 128.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_341012_2 1234888.K0A2J2_9VIRU 8.77e-36 137.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_61822_1 742733.HMPREF9469_05065 8.49e-26 100.0 2E0G5@1|root,324TP@2|Bacteria,1UQZN@1239|Firmicutes,258ST@186801|Clostridia,222Q1@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_170940_1 260827.Q6R6B4_9CAUD 1.23e-53 189.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales,4QNDH@10744|Podoviridae 10744|Podoviridae S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_365208_1 357276.EL88_12600 6.45e-14 76.6 2C054@1|root,341UI@2|Bacteria,4P449@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - k59_37308_2 1009370.ALO_12356 4.04e-07 53.5 28MVD@1|root,2ZB2Y@2|Bacteria,1VR3R@1239|Firmicutes,4H760@909932|Negativicutes 909932|Negativicutes S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_134418_3 1219035.NT2_13_00580 4.62e-49 176.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_328996_1 749222.Nitsa_1823 1.6e-11 72.0 COG0270@1|root,COG0270@2|Bacteria,1N0XD@1224|Proteobacteria 1224|Proteobacteria H C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_328996_3 1160721.RBI_II00417 2.69e-18 95.9 COG1066@1|root,COG1066@2|Bacteria,1UHUE@1239|Firmicutes,25E2V@186801|Clostridia,3WGAV@541000|Ruminococcaceae 186801|Clostridia O AAA domain - - - - - - - - - - - - AAA_25 k59_85896_1 1538804.A0A088F6T3_9CAUD 3.95e-88 282.0 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_98071_1 1618248.A0A0C5IB82_9CIRC 3.18e-67 216.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_122572_1 1692257.A0A0K1RL39_9CIRC 1.46e-31 120.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_122572_2 1692242.A0A0K1RKZ2_9CIRC 1.7e-33 130.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_122572_3 1692252.A0A0K1RL35_9CIRC 3.27e-43 152.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_219940_1 478749.BRYFOR_08560 3.51e-49 177.0 COG3378@1|root,COG3378@2|Bacteria 2|Bacteria KL Phage plasmid primase P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N,DUF3854,P22_AR_N,Pox_D5 k59_1033_1 929704.Myrod_0677 5.37e-19 89.0 29YBU@1|root,30K66@2|Bacteria,4P9EC@976|Bacteroidetes,1IACQ@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_329098_1 312309.VF_2017 1.43e-41 140.0 2CPEB@1|root,32SIW@2|Bacteria,1MZE0@1224|Proteobacteria,1SARU@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_329098_3 986075.CathTA2_2439 9.31e-11 66.2 COG0270@1|root,COG0270@2|Bacteria,1TPNE@1239|Firmicutes,4HHQR@91061|Bacilli 91061|Bacilli H C-5 cytosine-specific DNA methylase - - - - - - - - - - - - DNA_methylase k59_365288_4 1231377.C426_0888 4.37e-05 42.4 2DG0P@1|root,2ZTZD@2|Bacteria 2|Bacteria S Putative lactococcus lactis phage r1t holin - - - - - - - - - - - - Phage_r1t_holin k59_25235_1 1234888.K0A2J2_9VIRU 4.16e-45 165.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_25235_3 115711.CP_0543 4.6e-22 95.5 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_172058_2 1618248.A0A0C5IB82_9CIRC 7.74e-72 231.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_293655_2 395495.Lcho_0484 6.9e-18 84.7 COG2227@1|root,COG2520@1|root,COG2227@2|Bacteria,COG2520@2|Bacteria 2|Bacteria J tRNA (guanine(37)-N(1))-methyltransferase activity - - - - - - - - - - - - Glycos_transf_2,Methyltransf_11,Methyltransf_21,Methyltransf_23,Methyltransf_25 k59_354485_6 1609634.A0A0C5AFT2_9VIRU 3.03e-126 371.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_111320_1 649639.Bcell_2721 7.32e-74 247.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,4HGW7@91061|Bacilli,1ZBWW@1386|Bacillus 91061|Bacilli D phage tail tape measure protein - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,SLT k59_183546_3 2003327.CAPSD_BPCHP 6.73e-27 110.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_160230_1 1385658.U5KPZ6_9VIRU 1.28e-151 446.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_378711_2 874267.G4KNQ9_9CAUD 3.25e-43 172.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - GO:0008150,GO:0016032,GO:0019058,GO:0019068,GO:0044403,GO:0044419,GO:0051704,GO:0098003 - - - - - - - - - - - k59_99248_4 1986029.Q9MBM3_9VIRU 2.18e-06 57.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_319645_1 36033.XP_001645168.1 1.63e-13 74.3 COG0465@1|root,KOG0743@2759|Eukaryota,38CMD@33154|Opisthokonta,3NVKH@4751|Fungi,3QKI7@4890|Ascomycota,3RRCF@4891|Saccharomycetes,3RYH4@4893|Saccharomycetaceae 4751|Fungi O Belongs to the AAA ATPase family BCS1 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006810,GO:0006996,GO:0007005,GO:0007006,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017004,GO:0017062,GO:0017111,GO:0019866,GO:0022607,GO:0022857,GO:0022884,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032978,GO:0032979,GO:0033036,GO:0033108,GO:0033365,GO:0034551,GO:0034613,GO:0034622,GO:0042623,GO:0042886,GO:0042887,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0051131,GO:0051179,GO:0051204,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065003,GO:0070585,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0072594,GO:0072655,GO:0072657,GO:0090150,GO:1904680 - ko:K08900 - - - - ko00000,ko03029 - - - AAA,BCS1_N k59_367605_2 1609634.A0A0C5ANA6_9VIRU 5.6e-46 159.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_246226_1 1408303.JNJJ01000084_gene2553 4.96e-58 202.0 COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,4HCHZ@91061|Bacilli,1ZDD8@1386|Bacillus 91061|Bacilli L Virulence-associated protein E - - - - - - - - - - - - VirE k59_307418_3 1219035.NT2_13_00580 5.2e-74 244.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_3673_1 1609634.A0A0C5AFV4_9VIRU 2.53e-14 72.4 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_3673_3 1385658.U5KNR1_9VIRU 9.65e-75 239.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_3673_6 1385658.U5KPZ6_9VIRU 1.06e-194 560.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_331859_1 868864.Dester_0345 1.48e-17 87.8 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2G3XK@200783|Aquificae 200783|Aquificae L 5'-3' exonuclease - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A k59_222476_2 67352.JODS01000051_gene2656 4.37e-07 52.4 2ERK6@1|root,33J5P@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_136892_8 1121033.AUCF01000017_gene3816 1.3e-20 90.1 COG0741@1|root,COG0741@2|Bacteria,1N0U8@1224|Proteobacteria,2UICK@28211|Alphaproteobacteria,2JTZJ@204441|Rhodospirillales 204441|Rhodospirillales M lytic transglycosylase activity - - - - - - - - - - - - - k59_367609_1 105154.Q9MBU3_9VIRU 6.1e-18 85.5 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_64474_1 1322246.BN4_10061 8.26e-19 87.4 COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42M4P@68525|delta/epsilon subdivisions,2WIKX@28221|Deltaproteobacteria,2M9KK@213115|Desulfovibrionales 28221|Deltaproteobacteria M PFAM Polysaccharide biosynthesis protein pseB - 4.2.1.115 ko:K15894 ko00520,map00520 - R09697 RC02609 ko00000,ko00001,ko01000 - - - Polysacc_synt_2 k59_331996_1 1234888.K0A2J2_9VIRU 1.11e-57 196.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_88689_1 266834.SM_b20549 4.5e-06 52.8 COG4725@1|root,COG4725@2|Bacteria 2|Bacteria KT Belongs to the MT-A70-like family - - - - - - - - - - - - MT-A70 k59_355931_2 1357423.S5MPJ2_9CAUD 3.28e-11 63.5 4QDJF@10239|Viruses,4QVQ0@35237|dsDNA viruses no RNA stage,4QR89@28883|Caudovirales,4QICF@10662|Myoviridae 10662|Myoviridae S Virus neck protein - GO:0005575,GO:0019012 - - - - - - - - - - - k59_184654_2 1161401.ASJA01000008_gene1655 2.78e-07 51.6 COG3567@1|root,COG3567@2|Bacteria,1QNPU@1224|Proteobacteria,2U19C@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage-associated protein, HI1409 family - - - ko:K09961 - - - - ko00000 - - - DUF1073 k59_270703_2 1193181.BN10_650005 4.52e-16 77.8 COG2131@1|root,COG2131@2|Bacteria,2IJ94@201174|Actinobacteria,4FHCM@85021|Intrasporangiaceae 201174|Actinobacteria F MafB19-like deaminase - - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_344793_7 1234888.K0A2J2_9VIRU 9.69e-39 144.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_223690_3 1121468.AUBR01000008_gene2081 1.06e-05 48.9 COG4570@1|root,COG4570@2|Bacteria,1UDK7@1239|Firmicutes,24T1T@186801|Clostridia,42INU@68295|Thermoanaerobacterales 186801|Clostridia L PFAM endodeoxyribonuclease RusA - - 3.1.22.4 ko:K01160 - - - - ko00000,ko01000,ko03400 - - - RusA k59_247481_1 532075.B3VCW6_9CAUD 1.13e-22 94.0 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QPEB@28883|Caudovirales,4QNC3@10744|Podoviridae 10744|Podoviridae S endonuclease activity - - - - - - - - - - - - - k59_113631_1 278957.ABEA03000120_gene1205 7.77e-41 151.0 COG0714@1|root,COG0714@2|Bacteria 2|Bacteria KLT Associated with various cellular activities - - 3.6.4.12 ko:K03551,ko:K03924,ko:K04748 ko03440,map03440 - R00294 RC02794 ko00000,ko00001,ko01000,ko03400 3.D.4.10 - - AAA_11,AAA_12,AAA_5,DUF3987,PIN_4 k59_113631_13 100226.SCO5064 0.000132 53.5 COG0553@1|root,COG0553@2|Bacteria,2GISC@201174|Actinobacteria 201174|Actinobacteria L helicase - - - - - - - - - - - - HHH_5,Helicase_C,SNF2_N k59_113631_18 234267.Acid_1347 6.96e-23 112.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,3Y3X3@57723|Acidobacteria 57723|Acidobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_113631_22 861360.AARI_03880 9.09e-10 68.9 COG5519@1|root,COG5519@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - PriCT_1,Prim-Pol k59_15976_1 748280.NH8B_0541 2.22e-09 65.5 COG4675@1|root,COG4675@2|Bacteria 2|Bacteria M tail collar domain protein - - - - - - - - - - - - Collar,PTR,Peptidase_S74,Phage_fiber_2 k59_90055_3 1120948.KB903243_gene2721 9.26e-07 59.7 COG3266@1|root,COG3266@2|Bacteria,2I302@201174|Actinobacteria,4EF87@85010|Pseudonocardiales 201174|Actinobacteria S response to copper ion - - - - - - - - - - - - Big_5,DUF4082 k59_368954_3 1609634.A0A0C5AFV4_9VIRU 2.48e-50 184.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_40964_1 2003327.CAPSD_BPCHP 2.91e-24 108.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_225472_1 314230.DSM3645_06504 2.09e-43 150.0 COG1089@1|root,COG1089@2|Bacteria,2IWZ4@203682|Planctomycetes 203682|Planctomycetes M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose gmd - 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd k59_225474_1 1232410.KI421417_gene2761 1.14e-28 120.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1R97W@1224|Proteobacteria 1224|Proteobacteria D Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_200726_1 115711.CP_0543 1.12e-09 55.8 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_139978_1 1234888.K0A2J2_9VIRU 1.03e-47 171.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_17321_1 1121890.AUDO01000002_gene557 8.88e-06 50.1 COG0642@1|root,COG2202@1|root,COG3452@1|root,COG3829@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3452@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,4NFC3@976|Bacteroidetes,1HWUK@117743|Flavobacteriia,2P0RI@237|Flavobacterium 976|Bacteroidetes T Histidine kinase-like ATPases - - - - - - - - - - - - CHASE,HATPase_c,PAS_3,PAS_9 k59_139979_1 1179778.PMM47T1_10725 4.74e-26 102.0 COG3108@1|root,COG3108@2|Bacteria,1N1HE@1224|Proteobacteria,1SCII@1236|Gammaproteobacteria 1236|Gammaproteobacteria S peptidase M15A - - - - - - - - - - - - Peptidase_M15_3 k59_164574_1 1618236.A0A0C5I2F3_9CIRC 1.85e-49 177.0 4QGVY@10239|Viruses,4QUKN@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_79434_1 297246.lpp2117 1.01e-65 231.0 COG0305@1|root,COG0305@2|Bacteria,1QWI1@1224|Proteobacteria,1RZ7K@1236|Gammaproteobacteria,1JDPV@118969|Legionellales 118969|Legionellales L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - AAA_25,Toprim_2 k59_166081_1 691965.D4P7I0_9CAUD 4.23e-31 118.0 4QDSZ@10239|Viruses,4QXJ8@35237|dsDNA viruses no RNA stage,4QPKE@28883|Caudovirales,4QM8R@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_56816_3 265729.GS18_0213905 4.76e-61 200.0 COG2877@1|root,COG2877@2|Bacteria,1TR2G@1239|Firmicutes,4HTSS@91061|Bacilli,1ZE1D@1386|Bacillus 91061|Bacilli M Belongs to the KdsA family kdsA - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 k59_227463_1 484018.BACPLE_00805 2.8e-07 60.5 2EVUA@1|root,33P81@2|Bacteria,4P82D@976|Bacteroidetes,2FV68@200643|Bacteroidia,4AU6A@815|Bacteroidaceae 976|Bacteroidetes - - - - - - - - - - - - - - - k59_94053_1 1410624.JNKK01000017_gene1975 4.46e-21 97.8 COG4695@1|root,COG4695@2|Bacteria,1TP8B@1239|Firmicutes,2497C@186801|Clostridia,27I52@186928|unclassified Lachnospiraceae 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_300661_6 1408424.JHYI01000010_gene658 2.04e-13 70.1 COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,4HCDG@91061|Bacilli,1ZBGM@1386|Bacillus 91061|Bacilli F COG2131 Deoxycytidylate deaminase comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_215825_1 691965.D4P7I3_9CAUD 4.45e-61 212.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_69458_1 883078.HMPREF9695_01543 1.22e-49 175.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2TSF9@28211|Alphaproteobacteria,3JRJJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_166278_1 688270.Celal_2482 3.7e-16 84.0 COG3119@1|root,COG3119@2|Bacteria,4NE9D@976|Bacteroidetes,1HY4G@117743|Flavobacteriia,1F7SQ@104264|Cellulophaga 976|Bacteroidetes P COGs COG3119 Arylsulfatase A - - - - - - - - - - - - Sulfatase k59_336880_2 1416009.V9VHP8_9CAUD 1.8e-20 89.0 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QNBQ@10744|Podoviridae 10744|Podoviridae S HNH endonuclease - - - - - - - - - - - - - k59_227666_2 1197951.I6R9K8_9CAUD 7.74e-116 343.0 4QFIC@10239|Viruses,4QXG2@35237|dsDNA viruses no RNA stage,4QTVA@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_360252_2 1618247.A0A0C5IMK7_9CIRC 2e-11 68.6 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_202819_1 1401065.HMPREF2130_10980 4.24e-48 169.0 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,2W8DU@28216|Betaproteobacteria,3T87D@506|Alcaligenaceae 28216|Betaproteobacteria S Phage terminase large subunit - - - - - - - - - - - - Terminase_3 k59_69466_1 1609634.A0A0C5ANA6_9VIRU 1.54e-10 66.6 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_300680_1 1692249.A0A0K1RLN8_9CIRC 1.4e-20 92.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_117347_1 742738.HMPREF9460_04053 1.72e-66 211.0 COG0270@1|root,COG0270@2|Bacteria,1TPNE@1239|Firmicutes,24B1A@186801|Clostridia,26A94@186813|unclassified Clostridiales 186801|Clostridia L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_33143_1 1609634.A0A0C5AFT2_9VIRU 1.75e-60 204.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_385711_1 1692244.A0A0K1RLR5_9CIRC 6.18e-39 137.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_338213_1 268960.REP_BCTVC 0.000594 43.9 4QB6C@10239|Viruses,4QUKM@29258|ssDNA viruses 10239|Viruses J Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_143486_1 84531.JMTZ01000019_gene3993 4.39e-23 103.0 COG5624@1|root,COG5624@2|Bacteria,1P7FN@1224|Proteobacteria,1T85B@1236|Gammaproteobacteria,1XA69@135614|Xanthomonadales 135614|Xanthomonadales K RNA polymerase II activating transcription factor binding - - - - - - - - - - - - - k59_118547_1 439292.Bsel_3009 1.34e-18 84.7 COG3780@1|root,COG4626@1|root,COG3780@2|Bacteria,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,4HAXI@91061|Bacilli,26PJM@186821|Sporolactobacillaceae 91061|Bacilli L Phage Terminase - - - - - - - - - - - - Terminase_1 k59_155950_1 1094563.MCQ_00278 2.87e-05 47.4 COG4675@1|root,COG4675@2|Bacteria,1N0FZ@1224|Proteobacteria,2UDXB@28211|Alphaproteobacteria,48T3C@772|Bartonellaceae 28211|Alphaproteobacteria S Phage Tail Collar Domain - - - - - - - - - - - - Collar k59_106816_2 1618248.A0A0C5IB82_9CIRC 1.07e-16 88.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_143495_1 1234888.K0A2J2_9VIRU 4.35e-70 234.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_313607_1 477184.KYC_12803 3.33e-24 96.3 29XIZ@1|root,30J9Y@2|Bacteria,1NNKQ@1224|Proteobacteria,2WHUE@28216|Betaproteobacteria,3T8BH@506|Alcaligenaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_313607_4 1401297.U3PIR1_9CAUD 4.8e-06 47.8 4QG7B@10239|Viruses,4QV9D@35237|dsDNA viruses no RNA stage,4QT29@28883|Caudovirales,4QNM0@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_264376_1 1379713.S5SYD9_9CIRC 8.59e-12 67.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_143501_1 1283079.M1IDW3_9CAUD 1.38e-07 53.9 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_373871_1 118163.Ple7327_2120 4.31e-25 103.0 COG4627@1|root,COG4627@2|Bacteria,1G34B@1117|Cyanobacteria 1117|Cyanobacteria S PFAM Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 k59_22413_4 767434.Fraau_0982 1.77e-33 120.0 2C6KN@1|root,32Y69@2|Bacteria,1N8AV@1224|Proteobacteria,1SFCN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S VRR-NUC domain - - - - - - - - - - - - VRR_NUC k59_22419_1 411464.DESPIG_00773 0.00019 48.5 2E57E@1|root,32ZZZ@2|Bacteria,1NATW@1224|Proteobacteria,436CJ@68525|delta/epsilon subdivisions,2X0XN@28221|Deltaproteobacteria,2MDQD@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_254526_2 626418.bglu_1g20780 3.15e-19 84.7 COG4422@1|root,COG4422@2|Bacteria,1MXQI@1224|Proteobacteria,2VJP8@28216|Betaproteobacteria,1K05N@119060|Burkholderiaceae 28216|Betaproteobacteria S PFAM Gp37Gp68 family protein - - - - - - - - - - - - DUF5131 k59_266314_6 1286632.P278_33700 0.0 1035.0 28I9J@1|root,2Z8C8@2|Bacteria,4P06R@976|Bacteroidetes,1I7XB@117743|Flavobacteriia 976|Bacteroidetes S Bacteriophage replication gene A protein (GPA) - - - - - - - - - - - - Phage_GPA k59_266314_7 1288298.rosmuc_01659 6.62e-188 527.0 2DBBW@1|root,2Z8AR@2|Bacteria,1R492@1224|Proteobacteria,2UP8C@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Microvirus H protein (pilot protein) - - - - - - - - - - - - Microvir_H k59_266314_8 1286632.P278_33640 9.53e-36 124.0 28HGS@1|root,2Z7SJ@2|Bacteria,4NERU@976|Bacteroidetes,1HZIZ@117743|Flavobacteriia 976|Bacteroidetes S Major spike protein (G protein) - - - - - - - - - - - - Phage_G k59_242408_1 1297569.MESS2_860020 1.43e-38 137.0 2CFWB@1|root,2Z8W6@2|Bacteria,1PRU1@1224|Proteobacteria,2TUGM@28211|Alphaproteobacteria,43MY9@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Antitoxin of toxin-antitoxin stability system - - - - - - - - - - - - - k59_11427_5 1385658.U5KPZ6_9VIRU 9.69e-117 356.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_387825_2 1125863.JAFN01000001_gene3559 2.45e-11 63.5 2DS6A@1|root,33ERD@2|Bacteria,1Q2WN@1224|Proteobacteria,4328V@68525|delta/epsilon subdivisions,2WXUD@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_278739_2 272942.RCAP_rcc02742 2.37e-39 148.0 COG0270@1|root,COG0270@2|Bacteria,1PPPG@1224|Proteobacteria,2VAY2@28211|Alphaproteobacteria,1FD1R@1060|Rhodobacter 28211|Alphaproteobacteria H C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_278739_5 224911.27352791 2.35e-17 81.3 COG0817@1|root,COG0817@2|Bacteria,1NDKU@1224|Proteobacteria,2UFCY@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC - 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - - k59_22633_1 935261.JAGL01000009_gene1177 9.39e-53 183.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT52@1224|Proteobacteria,2TVNI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_2 k59_266321_1 1636271.A0A0E3JI89_9CAUD 2.27e-14 73.6 4QH9H@10239|Viruses,4QTW5@28883|Caudovirales,4QN1C@10699|Siphoviridae 10699|Siphoviridae S kinase activity - - - - - - - - - - - - - k59_145771_1 742740.HMPREF9474_02278 1.23e-48 179.0 28JED@1|root,2Z98K@2|Bacteria,1TW1U@1239|Firmicutes,24CFD@186801|Clostridia,2226E@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - GerE k59_145771_2 478749.BRYFOR_08535 1.23e-52 173.0 29YRZ@1|root,30KMY@2|Bacteria,1V4Y4@1239|Firmicutes,24HPY@186801|Clostridia 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - DUF2800 k59_145771_5 428125.CLOLEP_01379 1.34e-61 203.0 COG0553@1|root,COG0553@2|Bacteria,1TS9W@1239|Firmicutes,24CGX@186801|Clostridia,3WN6X@541000|Ruminococcaceae 186801|Clostridia KL Helicase conserved C-terminal domain - - - - - - - - - - - - - k59_120593_2 1385658.U5KPZ6_9VIRU 1.64e-162 476.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_206910_5 335992.SAR11_0448 1.37e-09 62.0 COG4547@1|root,COG4547@2|Bacteria,1MX11@1224|Proteobacteria,2TS4N@28211|Alphaproteobacteria,4BPRN@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria H Cobalamin biosynthesis protein CobT cobT - 6.6.1.2 ko:K09883 ko00860,ko01100,map00860,map01100 - R05227 RC02000 ko00000,ko00001,ko01000 - - - CobT,CobT_C k59_61068_1 1234888.K0A2J2_9VIRU 6.78e-11 62.8 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_61068_6 483216.BACEGG_02720 5.05e-10 67.8 2EVUA@1|root,33P81@2|Bacteria,4P82D@976|Bacteroidetes,2FV68@200643|Bacteroidia,4AU6A@815|Bacteroidaceae 976|Bacteroidetes - - - - - - - - - - - - - - - k59_61068_7 1234888.K0A2J2_9VIRU 1.18e-140 417.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_85393_8 1496688.ER33_07875 0.000844 48.9 COG2896@1|root,COG2896@2|Bacteria,1G0VS@1117|Cyanobacteria,22S5C@167375|Cyanobium 1117|Cyanobacteria C Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM k59_219099_4 156889.Mmc1_1720 2.37e-72 246.0 28QU5@1|root,2ZD9H@2|Bacteria,1RAU8@1224|Proteobacteria,2UAGW@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_219099_12 1166018.FAES_1814 1.39e-21 92.0 COG3108@1|root,COG3108@2|Bacteria,4NW30@976|Bacteroidetes,47T29@768503|Cytophagia 976|Bacteroidetes S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k59_219099_17 333138.LQ50_04395 3.73e-72 244.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H9YP@91061|Bacilli,1ZB0Z@1386|Bacillus 91061|Bacilli KL SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_291883_1 145579.CAPSD_BPPHM 1.6e-36 142.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_219103_1 160488.PP_2283 5.54e-25 103.0 2ATMD@1|root,31J5V@2|Bacteria,1RH31@1224|Proteobacteria,1SPN9@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Tail tubular protein - - - - - - - - - - - - Tube k59_328401_1 716928.AJQT01000109_gene1179 9.55e-22 95.1 COG0863@1|root,COG0863@2|Bacteria,1PCS4@1224|Proteobacteria,2VDM8@28211|Alphaproteobacteria,4BIRX@82115|Rhizobiaceae 28211|Alphaproteobacteria H DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_73213_1 1788454.A0A190WHE4_9CIRC 1.73e-42 155.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_109643_2 1609634.A0A0C5ANA6_9VIRU 2.04e-16 82.8 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_364784_1 1692244.A0A0K1RLR5_9CIRC 1.12e-68 221.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_97828_2 1692252.A0A0K1RL35_9CIRC 6.51e-95 289.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_231603_3 105154.Q9MBU6_9VIRU 2.13e-188 546.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_340846_1 889338.G3BM04_9CAUD 3.28e-46 163.0 4QC2G@10239|Viruses,4QV3V@35237|dsDNA viruses no RNA stage,4QPRR@28883|Caudovirales,4QI1T@10662|Myoviridae 10662|Myoviridae S Ribonucleotide reductase, small chain - - - - - - - - - - - - - k59_365108_1 1463864.JOGO01000047_gene4337 7.9e-26 105.0 COG0270@1|root,COG0270@2|Bacteria,2GK6Z@201174|Actinobacteria 201174|Actinobacteria L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_170748_1 742740.HMPREF9474_02303 2.54e-82 277.0 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia,221YV@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_12715_3 1385658.U5KPZ6_9VIRU 2.58e-175 509.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_304529_2 584708.Apau_0972 3.83e-12 63.9 COG2359@1|root,COG2359@2|Bacteria,3TBE1@508458|Synergistetes 508458|Synergistetes S PFAM Stage V sporulation protein S - - - ko:K06416 - - - - ko00000 - - - SpoVS k59_304529_6 1120936.KB907208_gene1116 6.92e-47 167.0 2FA48@1|root,342D2@2|Bacteria,2H6VX@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_62516_1 1165094.RINTHH_3920 8.95e-61 202.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_62516_2 1609634.A0A0C5AK24_9VIRU 1.6e-08 54.3 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_62516_3 1385658.U5KPZ6_9VIRU 3.93e-219 623.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_62516_5 1986029.Q9MBM6_9VIRU 1.25e-11 63.9 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_281516_3 410359.Pcal_0356 4.67e-11 75.1 COG0419@1|root,arCOG00368@2157|Archaea,2XQHC@28889|Crenarchaeota 28889|Crenarchaeota L Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex rad50 - - ko:K03546 - - - - ko00000,ko03400 - - - AAA_15,AAA_23,Rad50_zn_hook,SMC_N,SbcCD_C k59_281516_4 1453501.JELR01000001_gene2546 2.94e-19 83.6 2EIQ2@1|root,33CFI@2|Bacteria,1NHAI@1224|Proteobacteria,1SSQC@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_329802_1 931276.Cspa_c10280 8.31e-06 54.7 COG5301@1|root,COG5301@2|Bacteria,1UG0D@1239|Firmicutes,24M5I@186801|Clostridia,36K9E@31979|Clostridiaceae 186801|Clostridia D nuclear chromosome segregation - - - - - - - - - - - - - k59_268921_2 1165094.RINTHH_3920 4.65e-94 288.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_268921_5 105154.Q9MBU3_9VIRU 1.21e-09 62.8 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_171738_2 1500301.JQMF01000003_gene4211 3.5e-26 105.0 29X6Q@1|root,30IVV@2|Bacteria,1QZEA@1224|Proteobacteria,2TY78@28211|Alphaproteobacteria,4B9JD@82115|Rhizobiaceae 28211|Alphaproteobacteria S RecT family - - - - - - - - - - - - RecT k59_123306_1 366394.Smed_1925 5.23e-24 100.0 29X6Q@1|root,30IVV@2|Bacteria,1QZEA@1224|Proteobacteria,2TY78@28211|Alphaproteobacteria,4B9JD@82115|Rhizobiaceae 28211|Alphaproteobacteria S RecT family - - - - - - - - - - - - RecT k59_98815_3 1082931.KKY_773 2.14e-09 67.8 28JTG@1|root,2Z7PY@2|Bacteria,1QVNY@1224|Proteobacteria,2TXVN@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_341750_2 269482.Bcep1808_3253 2.66e-29 109.0 COG3108@1|root,COG3108@2|Bacteria,1N1HE@1224|Proteobacteria,2VTZR@28216|Betaproteobacteria,1K8H9@119060|Burkholderiaceae 28216|Betaproteobacteria S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k59_38025_2 521011.Mpal_0129 0.000633 52.8 arCOG02521@1|root,arCOG02521@2157|Archaea 2157|Archaea E Glycoside hydrolase family 28 - - - - - - - - - - - - Beta_helix,Pectate_lyase_3 k59_38025_4 1123508.JH636439_gene1958 4.32e-08 62.8 COG5283@1|root,COG5283@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - PhageMin_Tail k59_98816_1 1788444.A0A190WHB9_9CIRC 9.94e-61 200.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_256804_1 1121896.JMLU01000052_gene1259 6.28e-10 59.3 COG3108@1|root,COG3108@2|Bacteria,4P9W9@976|Bacteroidetes,1INI1@117743|Flavobacteriia,2NZQD@237|Flavobacterium 976|Bacteroidetes S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k59_147463_2 1348657.M622_06935 5.96e-17 90.9 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2VHG5@28216|Betaproteobacteria,2KUVR@206389|Rhodocyclales 206389|Rhodocyclales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k59_208454_2 469610.HMPREF0189_01114 1.98e-09 60.5 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,2VSX1@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_136333_1 1788444.A0A190WHB9_9CIRC 5.2e-09 58.5 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_245543_2 1408303.JNJJ01000151_gene2926 1.99e-09 58.2 2DNRS@1|root,32YU9@2|Bacteria,1VI43@1239|Firmicutes,4IN8K@91061|Bacilli,1ZN17@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k59_209779_2 1609634.A0A0C5AFV4_9VIRU 2.32e-212 605.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_209779_3 1609634.A0A0C5ANA6_9VIRU 1.38e-31 122.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_209779_5 1609634.A0A0C5AFT2_9VIRU 3.09e-83 259.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_112009_2 1464048.JNZS01000007_gene4664 0.000371 50.1 COG3209@1|root,COG3534@1|root,COG3209@2|Bacteria,COG3534@2|Bacteria,2I35N@201174|Actinobacteria,4DMW8@85008|Micromonosporales 201174|Actinobacteria M COG3209 Rhs family protein - - - - - - - - - - - - Laminin_G_3 k59_38883_1 1217656.F964_03381 9.74e-32 142.0 COG0454@1|root,COG1040@1|root,COG0456@2|Bacteria,COG1040@2|Bacteria,1QV41@1224|Proteobacteria,1RSAP@1236|Gammaproteobacteria,3NM26@468|Moraxellaceae 1236|Gammaproteobacteria K acetyltransferase - - - - - - - - - - - - - k59_38883_4 693746.OBV_28450 4.29e-11 70.9 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,2N6XB@216572|Oscillospiraceae 186801|Clostridia L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_14084_1 1622190.A0A0E3T6K6_9CAUD 2.31e-49 202.0 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_14084_2 717606.PaecuDRAFT_4465 1.86e-08 66.6 COG2730@1|root,COG3209@1|root,COG2730@2|Bacteria,COG3209@2|Bacteria 2|Bacteria M self proteolysis - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - Cellulase,Cytochrom_C,Dockerin_1,F5_F8_type_C,Glyco_hydro_43,RicinB_lectin_2,Ricin_B_lectin k59_306638_1 1609634.A0A0C5AFV4_9VIRU 1.02e-91 287.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_355172_2 1468411.X2KU72_9CAUD 4.01e-18 84.0 4QF7M@10239|Viruses,4QYGN@35237|dsDNA viruses no RNA stage,4QSE1@28883|Caudovirales,4QM9Q@10699|Siphoviridae 10699|Siphoviridae S AAA domain - - - - - - - - - - - - - k59_294373_1 1122173.AXVL01000018_gene438 6.94e-78 254.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,378AG@32066|Fusobacteria 32066|Fusobacteria S TIGRFAM Phage - - - - - - - - - - - - - k59_124615_2 1692244.A0A0K1RLR5_9CIRC 2.43e-80 250.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_269873_4 1127515.H9C0H6_9CAUD 1.29e-35 146.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QI9F@10662|Myoviridae 10662|Myoviridae S Type III restriction enzyme, res subunit - - - - - - - - - - - - - k59_379501_1 1234888.K0A2J2_9VIRU 3.86e-19 89.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_342949_4 105154.Q9MBU3_9VIRU 6.45e-09 60.8 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_342949_6 1609634.A0A0C5AFV4_9VIRU 1.64e-216 616.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_100047_3 279238.Saro_2760 6.2e-15 74.7 2EKAP@1|root,33E0Y@2|Bacteria,1NAAI@1224|Proteobacteria,2UI39@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_257983_2 223524.Q858R0_9VIRU 4.93e-11 57.8 4QE9V@10239|Viruses,4QUMN@29258|ssDNA viruses,4QP4N@10860|Inoviridae 10860|Inoviridae S integral to membrane - - - - - - - - - - - - - k59_257983_7 384360.A0JC21_9VIRU 1.2e-20 99.8 4QBCQ@10239|Viruses,4QUMB@29258|ssDNA viruses,4QP4S@10860|Inoviridae 10860|Inoviridae S DNA topoisomerase activity - - - - - - - - - - - - - k59_257983_13 1219076.N646_4295 6.02e-63 214.0 COG4128@1|root,COG4128@2|Bacteria,1RCY8@1224|Proteobacteria,1S4JQ@1236|Gammaproteobacteria,1XX6X@135623|Vibrionales 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_257983_14 1219076.N646_0606 1.38e-10 60.8 2CHQ6@1|root,33N6R@2|Bacteria,1NM75@1224|Proteobacteria,1SUNZ@1236|Gammaproteobacteria,1Y1UP@135623|Vibrionales 1236|Gammaproteobacteria S Protein of unknown function (DUF2523) - - - - - - - - - - - - DUF2523 k59_257983_15 1245471.PCA10_28690 6.57e-05 47.8 2FJ35@1|root,34ATG@2|Bacteria,1P008@1224|Proteobacteria,1SW0Q@1236|Gammaproteobacteria,1YK4X@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_136424_3 1380894.S5TR92_9CIRC 1.68e-39 148.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_211124_1 1304888.ATWF01000002_gene300 1.66e-29 126.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,2GGBD@200930|Deferribacteres 200930|Deferribacteres S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_89259_2 470145.BACCOP_01173 1.05e-35 139.0 COG1403@1|root,COG1403@2|Bacteria,4PN19@976|Bacteroidetes,2G0NU@200643|Bacteroidia 976|Bacteroidetes V HNH endonuclease - - - - - - - - - - - - - k59_284969_1 105154.Q9MBU3_9VIRU 6.64e-08 57.4 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_113452_1 1121441.AUCX01000014_gene507 4.46e-11 68.6 COG5563@1|root,COG5563@2|Bacteria,1Q0JE@1224|Proteobacteria,430IH@68525|delta/epsilon subdivisions,2X0GF@28221|Deltaproteobacteria,2MD65@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_320486_1 1238450.VIBNISOn1_1190023 5.73e-21 96.3 2F6W9@1|root,33ZCB@2|Bacteria,1NZ0D@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_344429_2 445974.CLORAM_02947 1.36e-17 80.1 2E3AH@1|root,32YA0@2|Bacteria,1VGN7@1239|Firmicutes 1239|Firmicutes S Protein of unknown function (DUF1064) - - - - - - - - - - - - DUF1064 k59_137716_2 1788455.A0A190WHF5_9CIRC 2.66e-17 82.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_333758_1 1123360.thalar_02874 3.25e-40 152.0 COG3108@1|root,COG4249@1|root,COG3108@2|Bacteria,COG4249@2|Bacteria,1R45G@1224|Proteobacteria,2U8DK@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Caspase domain - - - - - - - - - - - - Lipase_GDSL_2,Peptidase_C14,Peptidase_M15_3 k59_54063_1 1609634.A0A0C5ANA6_9VIRU 7.01e-21 90.9 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_286596_2 759938.F5BSB4_9CIRC 1.32e-24 107.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_345796_1 159087.Daro_2679 1.49e-15 76.6 COG2404@1|root,COG2404@2|Bacteria,1MXEH@1224|Proteobacteria,2VKWK@28216|Betaproteobacteria,2KX23@206389|Rhodocyclales 206389|Rhodocyclales S Phosphoesterase DHHA1 - - - - - - - - - - - - DHHA1 k59_321788_1 459349.CLOAM0317 2.08e-09 57.8 COG0789@1|root,COG0789@2|Bacteria,2NQ3P@2323|unclassified Bacteria 2|Bacteria K helix_turn_helix, mercury resistance ycgE - - ko:K19591,ko:K22491 - M00769 - - ko00000,ko00002,ko01504,ko03000 - - - MerR_1 k59_321788_2 1236514.BAKL01000055_gene3877 1.24e-21 88.2 2E38J@1|root,32Y88@2|Bacteria,4PA0K@976|Bacteroidetes,2FVX4@200643|Bacteroidia,4AU46@815|Bacteroidaceae 976|Bacteroidetes S VRR_NUC - - - - - - - - - - - - VRR_NUC k59_333773_1 145579.B_BPPHM 4.26e-19 84.0 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_333773_2 1385658.U5KNR1_9VIRU 3.28e-50 176.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_78612_1 691965.D4P7H8_9CAUD 1.61e-42 148.0 4QG1E@10239|Viruses,4QZE1@35237|dsDNA viruses no RNA stage,4QU6Q@28883|Caudovirales,4QMKH@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_297562_2 1121935.AQXX01000130_gene2425 6.07e-24 97.1 2AD08@1|root,312N7@2|Bacteria,1NDC4@1224|Proteobacteria,1SAPT@1236|Gammaproteobacteria,1XQHK@135619|Oceanospirillales 135619|Oceanospirillales S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_54230_1 1325372.N0DQT7_9CAUD 3.12e-82 268.0 4QAW1@10239|Viruses,4QWUW@35237|dsDNA viruses no RNA stage,4QR8A@28883|Caudovirales,4QJW9@10662|Myoviridae 10662|Myoviridae S nucleic acid binding - - - - - - - - - - - - - k59_31526_2 194699.Q775A7_BPBPP 3.52e-15 78.2 4QC5D@10239|Viruses,4QVY9@35237|dsDNA viruses no RNA stage,4QPVU@28883|Caudovirales,4QNN5@10744|Podoviridae 10744|Podoviridae S Protein of unknown function (DUF2800) - - - - - - - - - - - - - k59_17935_3 1234888.K0A2J2_9VIRU 8.11e-96 306.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_288396_3 1123296.JQKE01000023_gene909 1.03e-12 67.0 COG3926@1|root,COG3926@2|Bacteria,1MVXW@1224|Proteobacteria,2VRGU@28216|Betaproteobacteria,2KR8T@206351|Neisseriales 206351|Neisseriales S Glycosyl hydrolase 108 - - - - - - - - - - - - Glyco_hydro_108,PG_binding_3 k59_104244_2 942016.E9NIH0_9CAUD 2.71e-22 97.4 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_274411_1 6669.EFX86757 2.22e-14 79.3 COG0749@1|root,KOG0950@2759|Eukaryota,38BKB@33154|Opisthokonta,3BATG@33208|Metazoa,3CT13@33213|Bilateria,41U03@6656|Arthropoda 33208|Metazoa A DNA-directed DNA polymerase activity. It is involved in the biological process described with POLQ GO:0000018,GO:0000724,GO:0000725,GO:0000726,GO:0002200,GO:0002376,GO:0002377,GO:0002440,GO:0002520,GO:0002566,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003684,GO:0003824,GO:0003887,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006282,GO:0006284,GO:0006289,GO:0006302,GO:0006303,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007275,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010569,GO:0010605,GO:0016043,GO:0016445,GO:0016446,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0016829,GO:0016835,GO:0016887,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031324,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0036297,GO:0042623,GO:0042802,GO:0043142,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045738,GO:0045910,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051259,GO:0051260,GO:0051575,GO:0051716,GO:0060255,GO:0065003,GO:0065007,GO:0070013,GO:0071704,GO:0071840,GO:0071897,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097681,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2000042,GO:2000779,GO:2000780,GO:2001020,GO:2001021 2.7.7.7 ko:K02349,ko:K16618 ko03460,map03460 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,DNA_pol_A,Helicase_C k59_288397_1 1244869.H261_03308 4.8e-19 85.5 COG0827@1|root,COG0827@2|Bacteria,1QUSC@1224|Proteobacteria,2TW5J@28211|Alphaproteobacteria,2JZ6A@204441|Rhodospirillales 204441|Rhodospirillales L DNA restriction-modification system - - - - - - - - - - - - - k59_288397_2 343509.SG0727 5.86e-21 93.2 COG0270@1|root,COG0270@2|Bacteria,1NPQG@1224|Proteobacteria,1S07Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_226431_1 1618247.A0A0C5IMK7_9CIRC 5.93e-06 50.8 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_43383_1 1609634.A0A0C5AFV4_9VIRU 4.44e-92 286.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_31713_1 1123508.JH636440_gene2856 8.7e-06 52.0 COG4712@1|root,COG4712@2|Bacteria,2J0S4@203682|Planctomycetes 203682|Planctomycetes S PFAM Rad52 22 family double-strand break repair protein - - - - - - - - - - - - Rad52_Rad22 k59_347447_2 537971.HCCG_01553 4.98e-27 113.0 COG0535@1|root,COG0535@2|Bacteria,1R4I0@1224|Proteobacteria,42MFB@68525|delta/epsilon subdivisions,2YTMU@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria C Elongator protein 3, MiaB family, Radical SAM - - - - - - - - - - - - Fer4_12,Radical_SAM k59_323508_2 1211115.ALIQ01000188_gene655 7.22e-25 106.0 28MS5@1|root,2ZB0J@2|Bacteria,1PTV9@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_311052_1 650150.ERH_1292 7.73e-10 68.6 28MKK@1|root,2ZAWR@2|Bacteria,1UYAT@1239|Firmicutes,3VSD5@526524|Erysipelotrichia 526524|Erysipelotrichia S Putative viral replication protein - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_117623_2 1541065.JRFE01000034_gene6108 9.45e-33 125.0 2CC4J@1|root,2Z7W8@2|Bacteria,1G4C9@1117|Cyanobacteria 1117|Cyanobacteria S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_289998_3 691965.D4P7D8_9CAUD 1.94e-07 50.1 4QBBW@10239|Viruses,4QXCP@35237|dsDNA viruses no RNA stage,4QQ3N@28883|Caudovirales,4QN1X@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_251558_1 1443113.LC20_03908 1.09e-38 145.0 COG2189@1|root,COG2189@2|Bacteria,1QUB9@1224|Proteobacteria,1RMSJ@1236|Gammaproteobacteria,41FHV@629|Yersinia 1236|Gammaproteobacteria L DNA methylase - - 2.1.1.72 ko:K07319 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_251558_2 1260251.SPISAL_07565 7.84e-54 189.0 COG0582@1|root,COG0582@2|Bacteria,1N2H9@1224|Proteobacteria,1T20S@1236|Gammaproteobacteria,1WYSN@135613|Chromatiales 135613|Chromatiales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k59_251558_3 58123.JOFJ01000017_gene4131 2.73e-67 215.0 28HRJ@1|root,2Z7YZ@2|Bacteria,2GKNT@201174|Actinobacteria,4EHAV@85012|Streptosporangiales 201174|Actinobacteria - - - - - - - - - - - - - - - k59_166536_3 488538.SAR116_0387 7.45e-83 264.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS19@28211|Alphaproteobacteria,4BP86@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k59_251563_2 652103.Rpdx1_2982 1.25e-59 205.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT50@1224|Proteobacteria,2TTND@28211|Alphaproteobacteria,3JW9V@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L TOPRIM - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - AAA_25,DnaB_C,Toprim_2,Toprim_4 k59_301019_2 1379708.S5SYC3_9CIRC 1.64e-17 84.7 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_384797_1 371731.Rsw2DRAFT_3036 2.29e-14 81.6 COG2304@1|root,COG2304@2|Bacteria,1QWI7@1224|Proteobacteria,2TY8F@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Putative phage tail protein - - - - - - - - - - - - Phage-tail_3,VWA k59_203138_3 470.IX87_05020 2.79e-22 100.0 COG3756@1|root,COG3756@2|Bacteria,1N7P7@1224|Proteobacteria,1SDRK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF1376) - - - - - - - - - - - - DUF1376 k59_203138_5 1171373.PACID_13800 4.9e-36 150.0 COG1061@1|root,COG1061@2|Bacteria,2GIU5@201174|Actinobacteria,4DP3W@85009|Propionibacteriales 201174|Actinobacteria L Type III restriction enzyme, res subunit sdrA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - ResIII k59_34998_1 444861.E3SPQ5_9CAUD 7.01e-54 186.0 4QCWD@10239|Viruses,4QUQN@35237|dsDNA viruses no RNA stage,4QUCZ@28883|Caudovirales 28883|Caudovirales S DNA primase activity - - - - - - - - - - - - - k59_386259_1 411467.BACCAP_00968 6.01e-19 91.3 COG1032@1|root,COG1032@2|Bacteria 2|Bacteria C radical SAM domain protein - - - - - - - - - - - - B12-binding,Radical_SAM k59_144062_2 1448389.BAVQ01000002_gene2985 3.28e-07 57.8 COG1475@1|root,COG1475@2|Bacteria,2GNRN@201174|Actinobacteria 201174|Actinobacteria K Belongs to the ParB family parB GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944 - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_326838_2 1618238.A0A0C5I2G8_9CIRC 6.42e-29 117.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_302685_2 1096930.L284_17050 2.41e-24 105.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT52@1224|Proteobacteria,2TVNI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_2 k59_217934_1 488538.SAR116_0393 6.43e-30 122.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT52@1224|Proteobacteria,2TVNI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_2 k59_58828_1 526118.D1FNQ5_9CAUD 1.71e-42 160.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_229765_1 688245.CtCNB1_3569 3e-59 204.0 COG5511@1|root,COG5511@2|Bacteria,1MVN4@1224|Proteobacteria,2VKKT@28216|Betaproteobacteria,4ADCZ@80864|Comamonadaceae 28216|Betaproteobacteria S phage portal protein, lambda - - - - - - - - - - - - Phage_portal_2 k59_229765_2 225937.HP15_670 7.9e-23 105.0 COG4653@1|root,COG4653@2|Bacteria,1MWMB@1224|Proteobacteria,1S4MJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_96594_1 1415166.NONO_c60570 1.6e-75 238.0 COG4641@1|root,COG4641@2|Bacteria,2H1Z7@201174|Actinobacteria 201174|Actinobacteria S Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_2 k59_181195_2 105154.Q9MBU6_9VIRU 1.33e-70 229.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_156713_1 1169152.AXVD01000020_gene354 5.65e-08 61.6 COG5280@1|root,COG5412@1|root,COG5280@2|Bacteria,COG5412@2|Bacteria,2GNNQ@201174|Actinobacteria,4G9E7@85025|Nocardiaceae 201174|Actinobacteria M phage tail tape measure protein - - - - - - - - - - - - PhageMin_Tail,SLT k59_46946_3 1172188.KB911820_gene2901 2.35e-20 89.0 2915B@1|root,2ZNSM@2|Bacteria,2HE7N@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_265032_1 1264700.L0MYI2_9CAUD 2.36e-162 479.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QI9F@10662|Myoviridae 10662|Myoviridae S Type III restriction enzyme, res subunit - - - - - - - - - - - - - k59_265032_3 1161931.J7FA59_9CAUD 1.59e-102 313.0 4QC5D@10239|Viruses,4QVY9@35237|dsDNA viruses no RNA stage,4QPVU@28883|Caudovirales,4QIJW@10662|Myoviridae 10662|Myoviridae S Protein of unknown function (DUF2800) - - - - - - - - - - - - - k59_265032_5 1236000.L0ARW0_9CAUD 6.9e-47 171.0 4QAW1@10239|Viruses,4QWUW@35237|dsDNA viruses no RNA stage,4QR8A@28883|Caudovirales,4QJW9@10662|Myoviridae 10662|Myoviridae S nucleic acid binding - - - - - - - - - - - - - k59_21284_1 1121344.JHZO01000003_gene778 1.58e-06 49.3 COG1573@1|root,COG1573@2|Bacteria,1V267@1239|Firmicutes,24DFW@186801|Clostridia,3WIGX@541000|Ruminococcaceae 186801|Clostridia L Uracil-DNA glycosylase udgA - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_21284_2 195253.Syn6312_0894 4.91e-09 59.3 COG0817@1|root,COG0817@2|Bacteria,1G6YP@1117|Cyanobacteria 1117|Cyanobacteria L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group - - - - - - - - - - - - - k59_351983_2 1379715.S5TMW6_9CIRC 6.79e-33 124.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_169376_1 1506572.A0A097ZPG0_9CIRC 1.9e-46 165.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_190415_1 279714.FuraDRAFT_3081 1.06e-17 90.5 COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,2VKFN@28216|Betaproteobacteria,2KRK4@206351|Neisseriales 206351|Neisseriales M Transglycosylase SLT domain slt - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - DUF4124,SLT k59_254723_3 1692244.A0A0K1RLR5_9CIRC 1.27e-90 276.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_48389_1 28072.Nos7524_3118 2.75e-43 152.0 COG0338@1|root,COG0338@2|Bacteria,1G2H8@1117|Cyanobacteria,1HK31@1161|Nostocales 1117|Cyanobacteria L PFAM D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_387911_2 697281.Mahau_2527 7.49e-72 236.0 COG0714@1|root,COG0714@2|Bacteria,1U8NZ@1239|Firmicutes,248X1@186801|Clostridia,42HXE@68295|Thermoanaerobacterales 186801|Clostridia S PFAM ATPase associated with various cellular activities AAA_3 - - - - - - - - - - - - AAA,AAA_3,AAA_5,Sigma54_activat k59_352164_2 82995.CR62_16760 2.7e-06 53.1 2DNU8@1|root,32Z5M@2|Bacteria,1RGT6@1224|Proteobacteria,1S5HA@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - Peptidase_S74 k59_363571_1 457398.HMPREF0326_01490 4e-31 117.0 COG0338@1|root,COG0338@2|Bacteria,1P85S@1224|Proteobacteria,42MJQ@68525|delta/epsilon subdivisions,2WM98@28221|Deltaproteobacteria,2MB81@213115|Desulfovibrionales 28221|Deltaproteobacteria L D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12,Peptidase_S78_2 k59_363577_2 339670.Bamb_5483 1.65e-14 71.6 COG3409@1|root,COG3409@2|Bacteria,1R4RS@1224|Proteobacteria,2VTC5@28216|Betaproteobacteria,1K80T@119060|Burkholderiaceae 28216|Betaproteobacteria M CHAP domain - - - - - - - - - - - - CHAP k59_190423_1 1131814.JAFO01000001_gene2086 1.31e-19 90.9 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,2TT3N@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_169577_1 1788442.A0A190WH98_9CIRC 8.63e-18 85.1 4QB6C@10239|Viruses,4QUKM@29258|ssDNA viruses 10239|Viruses J Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_48405_1 391587.KAOT1_11827 6.71e-06 53.1 COG1319@1|root,COG4886@1|root,COG1319@2|Bacteria,COG4886@2|Bacteria,4NHYW@976|Bacteroidetes,1HZU3@117743|Flavobacteriia 976|Bacteroidetes C Leucine-rich repeat (LRR) protein - - - - - - - - - - - - - k59_387928_1 411460.RUMTOR_01352 1.85e-50 163.0 2AIHK@1|root,318ZG@2|Bacteria,1V7P0@1239|Firmicutes,24KNU@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_242546_1 2880.D7FQU5 2.86e-09 63.5 COG5108@1|root,KOG1038@2759|Eukaryota 2759|Eukaryota K DNA-directed 5'-3' RNA polymerase activity RpoT GO:0000428,GO:0000959,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006351,GO:0006390,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034245,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0098798,GO:0140053,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K00960,ko:K10908,ko:K11446 - - - - ko00000,ko01000,ko01009,ko03029,ko03036 - - - RNA_pol,RPOL_N k59_341021_1 1618247.A0A0C5IMK7_9CIRC 1.26e-14 78.6 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_134422_4 1205683.CAKR01000001_gene2100 1.07e-20 97.4 2DBI5@1|root,2Z9EN@2|Bacteria,1PMHG@1224|Proteobacteria,1RQE1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Exodeoxyribonuclease VIII - - - ko:K10906 - - - - ko00000,ko01000,ko03400 - - - DUF3799 k59_365212_2 1109715.G9FHU3_9CAUD 6e-22 89.7 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QPEB@28883|Caudovirales,4QKT0@10699|Siphoviridae 10699|Siphoviridae S Recombination endonuclease VII - - - - - - - - - - - - - k59_365212_6 69328.PVLB_26682 2.28e-44 168.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria 1236|Gammaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_134424_1 1234888.K0A2J2_9VIRU 2.04e-54 186.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_1040_1 691965.D4P7E6_9CAUD 8.16e-129 426.0 4QAK6@10239|Viruses,4R01K@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_134496_1 145579.CAPSD_BPPHM 1.06e-52 188.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_110388_2 1609634.A0A0C5AFV4_9VIRU 3e-44 159.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_304844_1 1692252.A0A0K1RL35_9CIRC 9.54e-07 50.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_304844_2 1692242.A0A0K1RKZ2_9CIRC 6.95e-32 127.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_304844_3 1692242.A0A0K1RL37_9CIRC 4.14e-92 281.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_268331_1 186617.M9M8L2_9VIRU 9.48e-90 283.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_280850_2 1120963.KB894494_gene3663 4.02e-22 91.7 COG3772@1|root,COG3772@2|Bacteria,1N0ZQ@1224|Proteobacteria,1S9AE@1236|Gammaproteobacteria,2Q38I@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_171082_1 1234888.K0A2J2_9VIRU 3.22e-48 170.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_207729_2 1692258.A0A0K1RL51_9CIRC 3.84e-96 291.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_12924_1 866775.HMPREF9243_0770 0.00014 50.1 COG0438@1|root,COG0438@2|Bacteria,1TR6K@1239|Firmicutes,4HGDG@91061|Bacilli 91061|Bacilli M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon gtf1 - - - - - - - - - - - Glycos_transf_1 k59_208970_16 1095772.CAHH01000068_gene334 3.12e-07 54.3 2C4MW@1|root,32RKK@2|Bacteria,2IQ6A@201174|Actinobacteria 201174|Actinobacteria S pathogenesis lsr - - - - - - - - - - - Lsr2 k59_354547_4 202954.BBNK01000034_gene3794 1.57e-38 133.0 2A3Q7@1|root,30S7S@2|Bacteria,1NP2K@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_354547_16 1379281.AVAG01000008_gene1401 0.000758 50.8 COG0621@1|root,COG3551@1|root,COG0621@2|Bacteria,COG3551@2|Bacteria,1RB2G@1224|Proteobacteria,42UMV@68525|delta/epsilon subdivisions,2WR43@28221|Deltaproteobacteria,2MDHR@213115|Desulfovibrionales 28221|Deltaproteobacteria J Sulfotransferase family - - - - - - - - - - - - - k59_172226_1 1692252.A0A0K1RL35_9CIRC 1.41e-42 151.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_269326_2 935567.JAES01000001_gene2175 1.98e-12 71.6 COG3751@1|root,COG3751@2|Bacteria,1RJST@1224|Proteobacteria,1S5SD@1236|Gammaproteobacteria,1X617@135614|Xanthomonadales 135614|Xanthomonadales O 2OG-Fe(II) oxygenase superfamily - - - - - - - - - - - - 2OG-FeII_Oxy_3 k59_354550_2 1692252.A0A0K1RL35_9CIRC 3.6e-85 264.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_366337_2 113395.AXAI01000009_gene2577 5.53e-05 45.4 COG0741@1|root,COG0741@2|Bacteria,1MX5R@1224|Proteobacteria,2TVHC@28211|Alphaproteobacteria,3JUU6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Transglycosylase SLT domain - - - - - - - - - - - - SLT k59_196581_3 1385658.U5KPZ6_9VIRU 5.64e-173 506.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_196581_4 1609634.A0A0C5ANA6_9VIRU 2.13e-16 82.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_172227_1 1609634.A0A0C5AFV4_9VIRU 6.77e-20 89.4 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_172227_3 1986029.Q9MBM3_9VIRU 3.62e-42 152.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_184441_2 438753.AZC_3585 5.84e-89 277.0 28IR7@1|root,2Z8QR@2|Bacteria,1PBTP@1224|Proteobacteria,2U248@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_331708_1 1126885.I3VYU7_9CAUD 2.07e-06 55.1 4QAK6@10239|Viruses,4QVAN@35237|dsDNA viruses no RNA stage,4QQH3@28883|Caudovirales,4QKT9@10699|Siphoviridae 10699|Siphoviridae S chitin catabolic process - GO:0000270,GO:0001906,GO:0001907,GO:0005975,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009253,GO:0009605,GO:0009607,GO:0009617,GO:0016032,GO:0016052,GO:0019048,GO:0019058,GO:0019076,GO:0030203,GO:0031640,GO:0035821,GO:0035890,GO:0035891,GO:0039633,GO:0040011,GO:0043170,GO:0043207,GO:0044003,GO:0044004,GO:0044033,GO:0044035,GO:0044040,GO:0044041,GO:0044238,GO:0044278,GO:0044364,GO:0044403,GO:0044419,GO:0044659,GO:0044661,GO:0050896,GO:0051672,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051818,GO:0051883,GO:0052126,GO:0052192,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - - - - - - - - - - - k59_222315_1 1618257.A0A0C5IBI9_9CIRC 1.75e-81 253.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_222315_2 1692249.A0A0K1RLN8_9CIRC 5.69e-37 137.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_379904_2 2003327.CAPSD_BPCHP 4.24e-92 300.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_294938_2 1692244.A0A0K1RLR5_9CIRC 2.47e-50 167.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_125219_1 1054968.G0X4V1_9CAUD 1.43e-32 133.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNI0@10744|Podoviridae 10744|Podoviridae S viral capsid - GO:0003674,GO:0005488,GO:0005515,GO:0042802 - - - - - - - - - - - k59_125219_2 188350.Q8H9S6_9CAUD 1.31e-28 114.0 4QGE6@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_125219_3 313606.M23134_00538 0.000166 51.2 COG0729@1|root,COG0729@2|Bacteria,4NVBC@976|Bacteroidetes 976|Bacteroidetes M Chaperone of endosialidase - - - - - - - - - - - - Peptidase_S74 k59_295065_3 160488.PP_2293 1.18e-65 218.0 COG5410@1|root,COG5410@2|Bacteria,1N0W2@1224|Proteobacteria,1S03G@1236|Gammaproteobacteria 1236|Gammaproteobacteria K chromosome segregation - - - - - - - - - - - - - k59_184528_1 145579.CAPSD_BPPHM 4.11e-37 139.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_184528_3 115711.CP_0543 6.98e-16 79.7 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_343471_1 717785.HYPMC_1479 7.12e-19 95.5 COG0463@1|root,COG0463@2|Bacteria 2|Bacteria M Glycosyl transferase, family 2 - - - - - - - - - - - - F5_F8_type_C,Glyco_tranf_2_4,Glycos_transf_2,RGP k59_64449_1 1524880.A0A076G5J7_9VIRU 1.17e-26 111.0 4QE8X@10239|Viruses 10239|Viruses S Phage phiEco32-like COOH.NH2 ligase-type 2 - - - - - - - - - - - - - k59_234275_1 1035308.AQYY01000002_gene632 2.59e-08 67.8 COG2132@1|root,COG2132@2|Bacteria,1TQSU@1239|Firmicutes,24CJP@186801|Clostridia,260KE@186807|Peptococcaceae 186801|Clostridia Q Multicopper oxidase - - 1.16.3.3 ko:K06324 - - - - ko00000,ko01000 - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 k59_234275_5 579138.Zymop_0818 2.46e-42 155.0 28PTM@1|root,2ZCEU@2|Bacteria,1R5DD@1224|Proteobacteria,2TVG7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_234275_9 1114179.I2FLT8_9CAUD 8.59e-83 284.0 4QAUF@10239|Viruses,4QWIQ@35237|dsDNA viruses no RNA stage,4QUFS@28883|Caudovirales,4QNVK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_234275_10 1280001.BAOA01000081_gene3007 1.48e-31 115.0 2EVSB@1|root,33P68@2|Bacteria,1P3SK@1224|Proteobacteria,1SS80@1236|Gammaproteobacteria,1XYJ3@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1353) - - - - - - - - - - - - DUF1353 k59_259475_1 1234888.K0A2J2_9VIRU 7.77e-35 131.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_381210_2 467481.B0VK09_9CAUD 1.6e-16 79.3 4QB0W@10239|Viruses,4QZQH@35237|dsDNA viruses no RNA stage,4QQW9@28883|Caudovirales,4QN19@10699|Siphoviridae 10699|Siphoviridae S Protein of unknown function (DUF1064) - - - - - - - - - - - - - k59_381354_5 760192.Halhy_0673 1.55e-07 57.0 COG4122@1|root,COG4122@2|Bacteria 2|Bacteria E O-methyltransferase activity - - - - - - - - - - - - Glycos_transf_2,Methyltransf_24 k59_235403_1 742733.HMPREF9469_05020 1.57e-161 518.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,221IX@1506553|Lachnoclostridium 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_235403_2 742733.HMPREF9469_05021 1.41e-19 85.1 2ARVA@1|root,31H70@2|Bacteria,1V7JT@1239|Firmicutes,24JPE@186801|Clostridia,222RD@1506553|Lachnoclostridium 186801|Clostridia S Bacteriophage HK97-gp10, putative tail-component - - - - - - - - - - - - HK97-gp10_like k59_235403_3 428125.CLOLEP_01417 5.8e-56 181.0 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia,3WMXK@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_235403_6 436308.Nmar_1073 4.6e-10 71.6 COG3794@1|root,arCOG05978@1|root,arCOG07813@1|root,arCOG02926@2157|Archaea,arCOG05978@2157|Archaea,arCOG07813@2157|Archaea 2157|Archaea C LamG domain protein jellyroll fold domain protein - - 2.7.11.1 ko:K12567 ko05410,ko05414,map05410,map05414 - - - ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812 - - - Copper-bind,GSDH,Laminin_G_3,ThuA,fn3 k59_235403_9 411460.RUMTOR_01342 3.36e-73 228.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_235403_10 691965.D4P7D8_9CAUD 8.49e-18 79.0 4QBBW@10239|Viruses,4QXCP@35237|dsDNA viruses no RNA stage,4QQ3N@28883|Caudovirales,4QN1X@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_235403_12 691965.D4P7D6_9CAUD 5.66e-149 453.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_235403_13 411460.RUMTOR_01348 2.54e-156 456.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_247555_1 714943.Mucpa_3799 5.99e-25 106.0 28N1N@1|root,2ZB7Q@2|Bacteria,4NPUX@976|Bacteroidetes 976|Bacteroidetes H PFAM Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_1 k59_150459_2 543728.Vapar_1664 2.56e-76 238.0 COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2VIIR@28216|Betaproteobacteria,4A9KM@80864|Comamonadaceae 28216|Betaproteobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k59_211843_1 1609634.A0A0C5AFV4_9VIRU 1.45e-162 475.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_15905_3 36080.S2JJ24 9.62e-10 70.5 COG0553@1|root,KOG0386@2759|Eukaryota,38FDR@33154|Opisthokonta,3NX7W@4751|Fungi,1GW7T@112252|Fungi incertae sedis 4751|Fungi A Snf2-ATP coupling, chromatin remodelling complex snf21 GO:0000003,GO:0000086,GO:0000122,GO:0000166,GO:0000228,GO:0000278,GO:0000785,GO:0000790,GO:0000988,GO:0000990,GO:0000991,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006302,GO:0006323,GO:0006325,GO:0006333,GO:0006337,GO:0006338,GO:0006342,GO:0006351,GO:0006354,GO:0006355,GO:0006357,GO:0006366,GO:0006368,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007010,GO:0007049,GO:0007059,GO:0008026,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010959,GO:0015616,GO:0016043,GO:0016070,GO:0016458,GO:0016462,GO:0016514,GO:0016584,GO:0016586,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022402,GO:0022411,GO:0022414,GO:0022607,GO:0030554,GO:0031055,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031497,GO:0031498,GO:0031974,GO:0031981,GO:0032392,GO:0032508,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032879,GO:0032984,GO:0032986,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0034728,GO:0034756,GO:0035639,GO:0036094,GO:0040029,GO:0042393,GO:0042623,GO:0043044,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043269,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0044770,GO:0044772,GO:0044839,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051276,GO:0051321,GO:0051716,GO:0060255,GO:0061587,GO:0065007,GO:0070013,GO:0070035,GO:0070577,GO:0070603,GO:0071103,GO:0071704,GO:0071824,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140030,GO:0140033,GO:0140097,GO:0140110,GO:1900390,GO:1900393,GO:1900400,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1902679,GO:1903047,GO:1903506,GO:1903507,GO:1904949,GO:2000112,GO:2000113,GO:2001141 - ko:K11786 - - - - ko00000,ko01000,ko03021,ko03036 - - - Bromodomain,HSA,Helicase_C,QLQ,SNF2_N,SnAC k59_103476_2 1437882.AZRU01000122_gene4891 3.08e-40 152.0 COG0507@1|root,COG0507@2|Bacteria,1QFB3@1224|Proteobacteria,1TCHA@1236|Gammaproteobacteria,1YKBW@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria L PIF1-like helicase - - - - - - - - - - - - AAA_30,UvrD_C_2 k59_176606_1 1166948.JPZL01000002_gene1629 2.14e-28 109.0 2DRN8@1|root,33CCM@2|Bacteria,1NGRN@1224|Proteobacteria 1224|Proteobacteria - - - - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - - k59_310104_1 489825.LYNGBM3L_52630 3.62e-13 73.2 28K7U@1|root,2Z9VT@2|Bacteria,1G5VD@1117|Cyanobacteria,1HHP5@1150|Oscillatoriales 2|Bacteria - - - - - - - - - - - - - - Methyltransf_21 k59_103480_1 1134445.AJJM01000011_gene3537 1.57e-15 80.1 2CHG1@1|root,32YZS@2|Bacteria,2IRMN@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_30784_1 145579.CAPSD_BPPHM 3.34e-76 247.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_370276_2 1618257.A0A0C5IBI9_9CIRC 2.32e-10 64.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_273463_1 1163617.SCD_n02931 8.7e-12 66.2 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,2VS6Y@28216|Betaproteobacteria 28216|Betaproteobacteria S Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N k59_115212_1 1692258.A0A0K1RL51_9CIRC 1.19e-44 156.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_186336_1 742727.HMPREF9447_00823 6.92e-100 306.0 COG0399@1|root,COG0399@2|Bacteria,4NFQ8@976|Bacteroidetes,2FMKJ@200643|Bacteroidia,4ANKY@815|Bacteroidaceae 976|Bacteroidetes E Belongs to the DegT DnrJ EryC1 family - - 2.6.1.59 ko:K02805 - - - - ko00000,ko01000,ko01007 - - - DegT_DnrJ_EryC1 k59_54724_2 1206735.BAGG01000254_gene6172 1.4e-20 87.0 2EF8R@1|root,329C0@2|Bacteria,2HJRV@201174|Actinobacteria,4G79C@85025|Nocardiaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_91689_1 979533.F1D0V0_9CAUD 1.22e-116 359.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales,4QNDH@10744|Podoviridae 10744|Podoviridae S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_200590_2 1038858.AXBA01000002_gene3749 2.13e-23 91.7 294NR@1|root,2ZS22@2|Bacteria,1P6AD@1224|Proteobacteria,2UWFS@28211|Alphaproteobacteria,3F24E@335928|Xanthobacteraceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_322484_2 497964.CfE428DRAFT_0770 3.71e-24 99.4 2DSBU@1|root,33FEQ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_287354_1 1385658.U5KPZ6_9VIRU 1.15e-39 149.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_200594_2 443144.GM21_3820 0.000382 48.1 COG0535@1|root,COG0535@2|Bacteria 2|Bacteria I radical SAM domain protein - - - ko:K15045 ko05164,map05164 - - - ko00000,ko00001 - - - Fer4_12,Fer4_14,Radical_SAM,SPASM k59_260983_1 1380394.JADL01000006_gene5263 4.02e-79 268.0 COG2268@1|root,COG2268@2|Bacteria,1NT13@1224|Proteobacteria,2U335@28211|Alphaproteobacteria,2JXVD@204441|Rhodospirillales 204441|Rhodospirillales S Band 7 protein - - - - - - - - - - - - - k59_17370_2 49964.Q94MS1_9CAUD 2.75e-27 108.0 4QB4H@10239|Viruses,4QYQI@35237|dsDNA viruses no RNA stage,4QUAR@28883|Caudovirales,4QNUV@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_91901_1 1379725.S5TMY9_9CIRC 1.06e-93 286.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_358385_1 349123.Lreu23DRAFT_3091 2.19e-06 54.3 COG3935@1|root,COG3935@2|Bacteria,1TPPF@1239|Firmicutes,4HNK6@91061|Bacilli,3F7TX@33958|Lactobacillaceae 91061|Bacilli L Psort location Cytoplasmic, score - - - - - - - - - - - - DnaB_2,Phg_2220_C k59_322677_2 1051673.G0YQ57_9CAUD 4.02e-21 90.5 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNX8@10744|Podoviridae 10744|Podoviridae S N-acetylmuramoyl-L-alanine amidase activity - GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0008150,GO:0008745,GO:0016032,GO:0016787,GO:0016810,GO:0016811,GO:0019048,GO:0019058,GO:0019076,GO:0031640,GO:0032897,GO:0035821,GO:0035890,GO:0035891,GO:0039633,GO:0040011,GO:0043900,GO:0043901,GO:0043903,GO:0044003,GO:0044004,GO:0044364,GO:0044403,GO:0044419,GO:0044659,GO:0044661,GO:0046782,GO:0048519,GO:0048525,GO:0050789,GO:0050792,GO:0051701,GO:0051704,GO:0051817,GO:0051818,GO:0051883,GO:0052126,GO:0052192,GO:0061783,GO:0065007 - - - - - - - - - - - k59_103603_2 1219035.NT2_13_00580 2.01e-85 274.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_213659_1 882378.RBRH_00618 2.32e-07 52.8 COG2105@1|root,COG2105@2|Bacteria,1NIAM@1224|Proteobacteria,2VVWY@28216|Betaproteobacteria,1K8TK@119060|Burkholderiaceae 28216|Betaproteobacteria S PFAM AIG2 family protein - - - - - - - - - - - - GGACT k59_213659_2 188350.Q8H9W3_9CAUD 2.91e-23 103.0 4QE8X@10239|Viruses,4QYGD@35237|dsDNA viruses no RNA stage,4QRJF@28883|Caudovirales,4QNB2@10744|Podoviridae 10744|Podoviridae S Phage phiEco32-like COOH.NH2 ligase-type 2 - - - - - - - - - - - - - k59_260987_1 1392488.JHZY01000004_gene2405 7.22e-15 73.2 COG0629@1|root,COG0629@2|Bacteria,4NMI3@976|Bacteroidetes,1I1NH@117743|Flavobacteriia,2XK8S@283735|Leeuwenhoekiella 976|Bacteroidetes L Single-strand binding protein family - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_215185_3 479435.Kfla_5967 3.69e-13 68.2 COG0207@1|root,COG0207@2|Bacteria,2GKY0@201174|Actinobacteria,4DPMT@85009|Propionibacteriales 201174|Actinobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k59_116750_4 255470.cbdbA1247 3.11e-08 52.0 COG3422@1|root,COG3422@2|Bacteria,2GAX6@200795|Chloroflexi,34DIH@301297|Dehalococcoidia 301297|Dehalococcoidia S Domain of unknown function (DUF1508) - - - ko:K09946 - - - - ko00000 - - - DUF1508 k59_165893_1 1280944.HY17_04460 1.63e-19 92.0 COG3723@1|root,COG3723@2|Bacteria,1QZ88@1224|Proteobacteria 1224|Proteobacteria L RecT family - - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_227237_1 347834.RHE_CH01097 2.53e-39 142.0 28NGF@1|root,2ZBII@2|Bacteria,1R9KY@1224|Proteobacteria,2U1P7@28211|Alphaproteobacteria,4B747@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_289262_2 1262513.K7YB38_9CAUD 6.21e-41 153.0 4QBG0@10239|Viruses,4QWYZ@35237|dsDNA viruses no RNA stage,4QSGM@28883|Caudovirales,4QK1H@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_80957_1 1618260.A0A0C5I2C5_9CIRC 8.06e-57 190.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_300214_2 1234888.K0A2J2_9VIRU 8.11e-93 298.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_348395_2 1230341.MJ3_13589 1.01e-22 105.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1TSMG@1239|Firmicutes,4HBFH@91061|Bacilli 91061|Bacilli S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_215422_1 105154.Q9MBU6_9VIRU 3.26e-86 271.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_93773_2 261726.Q6R4V3_9CAUD 3.12e-27 112.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QJPJ@10662|Myoviridae 10662|Myoviridae S N-acetylmuramoyl-L-alanine amidase activity - GO:0005575,GO:0019012 - - - - - - - - - - - k59_311901_3 1385658.U5KPZ6_9VIRU 2.81e-173 506.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_324372_1 1040987.AZUY01000009_gene1189 9.95e-45 150.0 2FEUE@1|root,346TC@2|Bacteria,1MZPB@1224|Proteobacteria,2UC4Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_215430_1 936455.KI421499_gene5909 1.1e-13 79.0 COG3409@1|root,COG3772@1|root,COG3409@2|Bacteria,COG3772@2|Bacteria,1QW72@1224|Proteobacteria,2UBY3@28211|Alphaproteobacteria,3K0F5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - - k59_361220_1 1493511.A0A0E3FMF4_9CAUD 4.41e-22 95.1 4QC5H@10239|Viruses,4QPNZ@28883|Caudovirales,4QHUK@10662|Myoviridae 10662|Myoviridae S sigma factor activity - - - - - - - - - - - - - k59_46077_2 640513.Entas_3966 1.25e-21 93.6 COG3740@1|root,COG3740@2|Bacteria,1NHKT@1224|Proteobacteria,1S55B@1236|Gammaproteobacteria,3X476@547|Enterobacter 1236|Gammaproteobacteria S PFAM Peptidase U35, phage prohead HK97 - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78 k59_167365_1 608538.HTH_0548 1.59e-07 56.2 2A75B@1|root,30W16@2|Bacteria,2G5D4@200783|Aquificae 200783|Aquificae S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_58201_1 1380367.JIBC01000006_gene303 2.52e-14 77.4 28JKJ@1|root,2Z9DD@2|Bacteria,1MUN2@1224|Proteobacteria,2TST4@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage P22-like portal protein - - - - - - - - - - - - P22_portal k59_58462_1 991905.SL003B_3775 4.13e-09 64.7 COG3087@1|root,COG3087@2|Bacteria,1QU07@1224|Proteobacteria,2TR07@28211|Alphaproteobacteria,4BRB1@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria D peptidase U35 phage prohead HK97 u35 - - - - - - - - - - - Mu-like_gpT,Peptidase_S78 k59_106980_2 634504.Bgr_10230 9.08e-37 133.0 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2U7X4@28211|Alphaproteobacteria,48TF4@772|Bartonellaceae 28211|Alphaproteobacteria G Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_313801_1 1986029.Q9MBM7_9VIRU 7.03e-08 57.8 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_264515_1 356851.JOAN01000006_gene381 6.89e-05 47.8 COG3064@1|root,COG3064@2|Bacteria,2I61H@201174|Actinobacteria,4DMQE@85008|Micromonosporales 201174|Actinobacteria M Membrane - - - - - - - - - - - - - k59_9631_3 481448.Minf_2056 2.85e-08 57.0 COG3551@1|root,COG3551@2|Bacteria,46X4B@74201|Verrucomicrobia,37H9R@326457|unclassified Verrucomicrobia 74201|Verrucomicrobia M Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_3 k59_350219_1 1692250.A0A0K1RLR1_9CIRC 8.51e-64 204.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_106981_2 429009.Adeg_0412 8.1e-36 142.0 COG1241@1|root,COG4643@1|root,COG1241@2|Bacteria,COG4643@2|Bacteria,1UZJE@1239|Firmicutes,24FKH@186801|Clostridia,42FUS@68295|Thermoanaerobacterales 186801|Clostridia L Protein of unknown function (DUF3987) - - - - - - - - - - - - DUF3987 k59_278386_1 614083.AWQR01000015_gene2510 4.21e-31 125.0 COG2425@1|root,COG2425@2|Bacteria,1R55U@1224|Proteobacteria,2VKRA@28216|Betaproteobacteria,4AC01@80864|Comamonadaceae 28216|Betaproteobacteria S protein containing a von Willebrand factor type A (vWA) domain - - - ko:K11089 ko05322,map05322 - - - ko00000,ko00001 - - - TROVE k59_375480_2 570952.ATVH01000019_gene756 7.18e-38 146.0 COG1783@1|root,COG1783@2|Bacteria,1RAGC@1224|Proteobacteria,2U6JF@28211|Alphaproteobacteria,2JSIA@204441|Rhodospirillales 204441|Rhodospirillales S phage Terminase large subunit - - - - - - - - - - - - - k59_108449_1 1788455.A0A190WHF5_9CIRC 5.04e-40 144.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_254228_4 1234888.K0A2R8_9VIRU 3.07e-22 101.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_375490_1 932677.PAJ_0760 3.09e-26 112.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1RP8Z@1236|Gammaproteobacteria,3W0E4@53335|Pantoea 1236|Gammaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_108594_1 1122609.AUGT01000008_gene2868 1.05e-18 99.8 COG0366@1|root,COG0515@1|root,COG2133@1|root,COG3227@1|root,COG4733@1|root,COG0366@2|Bacteria,COG0515@2|Bacteria,COG2133@2|Bacteria,COG3227@2|Bacteria,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - 3.2.1.3 ko:K01178,ko:K14645,ko:K18546 ko00500,ko01100,ko02024,map00500,map01100,map02024 - R01790,R01791,R06199 - ko00000,ko00001,ko01000,ko01002,ko03110 - GH15 - Alpha-amylase,GSDH,He_PIG,PKD,Pro_Al_protease,SLH,Trypsin,fn3 k59_190053_2 1234888.K0A2J2_9VIRU 1.47e-111 343.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_169148_3 1051675.G0YQF5_9CAUD 1.86e-27 113.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_108620_1 1264700.L0MYI2_9CAUD 4.95e-77 247.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QI9F@10662|Myoviridae 10662|Myoviridae S Type III restriction enzyme, res subunit - - - - - - - - - - - - - k59_303731_3 877418.ATWV01000014_gene2783 2.62e-13 80.9 COG0739@1|root,COG0739@2|Bacteria,2J6RF@203691|Spirochaetes 203691|Spirochaetes M LysM domain M23 M37 peptidase domain protein nlpD - - - - - - - - - - - LysM,Peptidase_M23 k59_364817_5 1379788.I0CKB2_9VIRU 3.14e-20 101.0 4QD5V@10239|Viruses 10239|Viruses S Viral coat protein (S domain) - GO:0003674,GO:0003676,GO:0003723,GO:0005198,GO:0005488,GO:0005509,GO:0005575,GO:0008289,GO:0019012,GO:0019028,GO:0019030,GO:0039617,GO:0039660,GO:0043167,GO:0043169,GO:0044423,GO:0046872,GO:0097159,GO:1901363 - - - - - - - - - - - k59_158373_7 1035191.HMPREF0185_03555 2.18e-23 109.0 28I9J@1|root,2Z8C8@2|Bacteria,1NQUB@1224|Proteobacteria 1224|Proteobacteria S Bacteriophage replication gene A protein (GPA) - - - - - - - - - - - - Phage_GPA k59_12407_7 1122214.AQWH01000025_gene4965 0.000254 50.8 COG5281@1|root,COG5281@2|Bacteria,1R47M@1224|Proteobacteria,2TUIV@28211|Alphaproteobacteria,2PJW4@255475|Aurantimonadaceae 28211|Alphaproteobacteria S COG5281, Phage-related minor tail protein - - - - - - - - - - - - - k59_12407_11 398525.KB900701_gene5078 3.4e-27 129.0 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2TV2W@28211|Alphaproteobacteria,3JW1G@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S COG4733 Phage-related protein, tail component - - - - - - - - - - - - Phage-tail_3 k59_219213_1 1609634.A0A0C5AFV4_9VIRU 4.54e-87 277.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_24711_3 102129.Lepto7375DRAFT_7273 2.03e-11 65.1 2EHVE@1|root,33BKZ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_255457_1 1197951.I6R0Y7_9CAUD 1.31e-57 198.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales 28883|Caudovirales S DnaB-like helicase C terminal domain - - - - - - - - - - - - - k59_195209_61 765914.ThisiDRAFT_2068 1.41e-28 121.0 COG1573@1|root,COG3210@1|root,COG1573@2|Bacteria,COG3210@2|Bacteria,1MWX1@1224|Proteobacteria,1S2U7@1236|Gammaproteobacteria,1WWN0@135613|Chromatiales 135613|Chromatiales L TIGRFAM Phage SPO1 DNA polymerase-related protein - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_195209_64 1189612.A33Q_3767 3.76e-13 73.6 COG1948@1|root,COG1948@2|Bacteria,4P5FR@976|Bacteroidetes,47W39@768503|Cytophagia 976|Bacteroidetes L ERCC4 domain - - - - - - - - - - - - ERCC4,HHH_5 k59_195209_72 224719.Abm4_1676 1.6e-70 249.0 COG1199@1|root,arCOG00770@2157|Archaea,2XSWZ@28890|Euryarchaeota,23NV7@183925|Methanobacteria 183925|Methanobacteria L HELICc2 - - - - - - - - - - - - DEAD_2,Helicase_C_2,ResIII k59_159018_1 1121459.AQXE01000001_gene2744 5.99e-19 92.8 COG5164@1|root,COG5164@2|Bacteria,1N2FU@1224|Proteobacteria,42WNM@68525|delta/epsilon subdivisions,2WRNC@28221|Deltaproteobacteria 28221|Deltaproteobacteria K Collagen triple helix repeat (20 copies) - - - - - - - - - - - - - k59_110305_2 105154.Q9MBU3_9VIRU 2.65e-12 70.1 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_365237_2 388051.AUFE01000009_gene1840 2.13e-11 69.7 28JXH@1|root,2Z9MZ@2|Bacteria,1MXNC@1224|Proteobacteria,2WB28@28216|Betaproteobacteria,1K4ZI@119060|Burkholderiaceae 28216|Betaproteobacteria S RecT family - - - - - - - - - - - - RecT k59_49620_1 1385658.U5KPZ6_9VIRU 1.69e-109 336.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_329034_2 243090.RB11260 6.15e-09 57.8 COG1734@1|root,COG1734@2|Bacteria 2|Bacteria T zinc ion binding - - - ko:K06204 ko02026,map02026 - - - ko00000,ko00001,ko03000,ko03009,ko03021 - - - zf-dskA_traR k59_26019_1 105154.Q9MBU3_9VIRU 1.04e-17 84.3 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_208720_1 2002.JOEQ01000009_gene6492 7.48e-10 67.0 COG5434@1|root,COG5434@2|Bacteria 2|Bacteria M polygalacturonase activity - - - - - - - - - - - - Beta_helix,Glyco_hydro_28,Pectate_lyase_3 k59_38189_1 478749.BRYFOR_08513 4.45e-18 99.4 COG3409@1|root,COG3409@2|Bacteria 2|Bacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - Amidase_2,LysM,PG_binding_1 k59_99034_2 1692244.A0A0K1RLR5_9CIRC 2.01e-104 311.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_171970_1 1234888.K0A2J2_9VIRU 3.61e-123 372.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_171970_8 1234888.K0A2J2_9VIRU 8.15e-29 115.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_256999_1 1379709.S5TMV0_9CIRC 4.02e-18 89.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_173109_2 343509.SG1825 5.03e-12 69.3 COG0640@1|root,COG0640@2|Bacteria,1RGKD@1224|Proteobacteria,1S53G@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Helix-turn-helix domain - - - - - - - - - - - - HTH_36 k59_173109_5 1116375.VEJY3_09835 7.22e-32 114.0 COG2852@1|root,COG2852@2|Bacteria,1N2UX@1224|Proteobacteria,1TIHC@1236|Gammaproteobacteria,1XZ4M@135623|Vibrionales 135623|Vibrionales S Protein conserved in bacteria - - - - - - - - - - - - - k59_222053_1 525904.Tter_2414 4.41e-07 57.4 COG0209@1|root,COG0209@2|Bacteria,2NNVF@2323|unclassified Bacteria 2|Bacteria F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdZ GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k59_3139_3 1609634.A0A0C5ANA6_9VIRU 8.96e-16 79.7 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_148554_2 1420600.W5RNT1_9CIRC 2.24e-33 130.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_319207_3 68194.JNXR01000045_gene1278 3.15e-05 53.1 COG0451@1|root,COG0451@2|Bacteria,2GMHH@201174|Actinobacteria 201174|Actinobacteria M 3-beta hydroxysteroid dehydrogenase isomerase - GO:0000166,GO:0003674,GO:0003824,GO:0003854,GO:0004769,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0016020,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016853,GO:0016860,GO:0016863,GO:0030283,GO:0033764,GO:0036094,GO:0043167,GO:0043168,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901360,GO:1901363 1.1.1.145,1.1.1.412,5.3.3.1 ko:K16045,ko:K22320 ko00984,ko01120,map00984,map01120 - R09920 RC00146 ko00000,ko00001,ko01000 - - - 3Beta_HSD,Epimerase k59_222058_4 114615.BRADO2879 4.25e-11 64.7 COG2520@1|root,COG2520@2|Bacteria,1RIYU@1224|Proteobacteria,2U2ZF@28211|Alphaproteobacteria,3JSC4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 k59_39178_1 1609634.A0A0C5AFV4_9VIRU 8.16e-80 257.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_64114_1 1468179.A0A0C4K5Z2_9VIRU 1.31e-10 66.6 4QAKM@10239|Viruses 10239|Viruses S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_331510_2 1692253.A0A0K1RLM4_9CIRC 2.85e-28 115.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_39181_2 1234888.K0A2J2_9VIRU 1.42e-124 375.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_75920_2 1165094.RINTHH_3920 2.79e-50 172.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_211105_3 114615.BRADO6930 3.75e-11 63.5 2EHBB@1|root,33B36@2|Bacteria,1RGAQ@1224|Proteobacteria,2U70Q@28211|Alphaproteobacteria,3JZ8Y@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_211234_6 485913.Krac_9004 0.000409 43.5 2C5T0@1|root,337HV@2|Bacteria,2G9CN@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - k59_149964_1 105154.Q9MBU6_9VIRU 1.49e-91 294.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_149964_7 1385658.U5KPZ6_9VIRU 4.98e-25 106.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_198551_1 1211844.CBLM010000090_gene2700 2.17e-06 55.1 COG2189@1|root,COG2189@2|Bacteria,1UKK3@1239|Firmicutes,3VTXZ@526524|Erysipelotrichia 526524|Erysipelotrichia L DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_198551_2 1121918.ARWE01000001_gene1957 1.13e-23 95.1 COG1694@1|root,COG1694@2|Bacteria,1N02D@1224|Proteobacteria,42W8Z@68525|delta/epsilon subdivisions,2WS5B@28221|Deltaproteobacteria,43V1B@69541|Desulfuromonadales 28221|Deltaproteobacteria S MazG-like family - - - - - - - - - - - - MazG-like k59_344390_5 1524467.IV04_20460 3.61e-05 45.4 COG3108@1|root,COG3108@2|Bacteria,1RICX@1224|Proteobacteria,1S6D5@1236|Gammaproteobacteria,403G6@613|Serratia 1236|Gammaproteobacteria S Peptidase M15 - - - ko:K17733 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M15_4 k59_89368_1 378806.STAUR_2875 2.77e-10 70.1 COG5297@1|root,COG5297@2|Bacteria,1QZI4@1224|Proteobacteria,43CJ7@68525|delta/epsilon subdivisions,2X7TJ@28221|Deltaproteobacteria,2YXMV@29|Myxococcales 28221|Deltaproteobacteria G Glycosyl hydrolases family 6 - - 3.2.1.91 ko:K19668 ko00500,ko01100,ko02020,map00500,map01100,map02020 - R02886,R11308 RC00799 ko00000,ko00001,ko01000 - GH6 - CBM_3,Glyco_hydro_6,fn3 k59_295856_3 1453501.JELR01000001_gene2516 1.09e-64 254.0 COG4733@1|root,COG4926@1|root,COG4733@2|Bacteria,COG4926@2|Bacteria,1R77Q@1224|Proteobacteria,1S1WT@1236|Gammaproteobacteria,469QU@72275|Alteromonadaceae 1236|Gammaproteobacteria S Fibronectin type 3 domain - - - - - - - - - - - - - k59_126012_1 1986029.Q9MBM3_9VIRU 2.73e-56 188.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_234959_2 247156.NFA_15280 2.75e-13 78.2 2DB75@1|root,2Z7JY@2|Bacteria,2HY7E@201174|Actinobacteria 201174|Actinobacteria S Phage major capsid protein E - - - - - - - - - - - - Phage_cap_E k59_40331_3 438753.AZC_3588 1.95e-42 156.0 28MSK@1|root,2ZB0X@2|Bacteria,1R7CY@1224|Proteobacteria,2U2MY@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_101589_1 2003327.CAPSD_BPCHP 2.2e-55 192.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_284938_2 76869.PputGB1_3455 5.29e-13 74.7 2C2XN@1|root,32GT6@2|Bacteria,1REZE@1224|Proteobacteria,1SG9Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria S ERF superfamily - - - - - - - - - - - - ERF k59_284938_5 395964.KE386496_gene2574 3.61e-12 65.9 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,2TQWC@28211|Alphaproteobacteria,3NAJ6@45404|Beijerinckiaceae 28211|Alphaproteobacteria L PIF1-like helicase recD - 3.1.11.5 ko:K01144 - - - - ko00000,ko01000 - - - AAA_30,UvrD_C_2 k59_185077_1 240302.BN982_00531 3.87e-41 166.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,3NDXY@45667|Halobacillus 91061|Bacilli L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A k59_137668_3 1313421.JHBV01000006_gene351 6.86e-13 71.2 COG3023@1|root,COG3023@2|Bacteria,4NRQX@976|Bacteroidetes 976|Bacteroidetes V Psort location Cytoplasmic, score 8.96 - - 3.5.1.28 ko:K01447 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Amidase_2 k59_344399_2 1379722.S5SY31_9CIRC 7.45e-102 304.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_77208_3 1219035.NT2_13_00600 5.17e-30 122.0 290X3@1|root,2ZNIW@2|Bacteria,1P7TA@1224|Proteobacteria,2UXFQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_114739_3 251229.Chro_2612 1.36e-06 54.3 COG5002@1|root,COG5002@2|Bacteria,1GHEK@1117|Cyanobacteria 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c,HisKA,dCache_1 k59_357810_1 2003327.CAPSD_BPCHP 1.13e-19 93.2 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_260377_1 155148.Q9AYZ7_BPHK6 3.35e-26 108.0 4QBD3@10239|Viruses,4QXFU@35237|dsDNA viruses no RNA stage,4QQ7Z@28883|Caudovirales,4QNJ0@10744|Podoviridae 10744|Podoviridae S P22 coat protein - gene protein 5 - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0009987,GO:0016032,GO:0016043,GO:0019012,GO:0019028,GO:0019030,GO:0019058,GO:0019068,GO:0019069,GO:0019075,GO:0022607,GO:0039620,GO:0042802,GO:0042803,GO:0044085,GO:0044403,GO:0044419,GO:0044423,GO:0046729,GO:0046797,GO:0046983,GO:0051704,GO:0071840 - - - - - - - - - - - k59_260377_5 1121921.KB898706_gene3045 1.11e-70 240.0 28MJ5@1|root,2ZAVR@2|Bacteria,1R5CR@1224|Proteobacteria,1SCPR@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage stabilisation protein - - - - - - - - - - - - Phage_stabilise k59_260377_26 411468.CLOSCI_00223 6.16e-10 59.7 2E38J@1|root,32Y88@2|Bacteria,1VAXK@1239|Firmicutes,24N7K@186801|Clostridia,221KQ@1506553|Lachnoclostridium 186801|Clostridia S COG NOG18350 non supervised orthologous group - - - - - - - - - - - - VRR_NUC k59_260377_28 1096546.WYO_0205 8.87e-30 113.0 COG0647@1|root,COG0647@2|Bacteria 2|Bacteria G UMP catabolic process nagD - 2.7.1.25,3.1.3.41 ko:K00860,ko:K01101 ko00230,ko00627,ko00920,ko01100,ko01120,map00230,map00627,map00920,map01100,map01120 M00176 R00509,R03024,R04928 RC00002,RC00078,RC00151 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_6,Hydrolase_like k59_260377_29 742743.HMPREF9453_00576 1.46e-107 333.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H2W4@909932|Negativicutes 909932|Negativicutes L SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_260377_30 1211115.ALIQ01000188_gene622 2.66e-101 332.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,2UNT9@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_260377_31 936154.STP_0866 2.65e-20 91.3 28J2E@1|root,2Z8YX@2|Bacteria,1TRF9@1239|Firmicutes,4HKAQ@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF2815) - - - - - - - - - - - - DUF2815 k59_260377_33 755731.Clo1100_3566 1.15e-20 100.0 COG2887@1|root,COG2887@2|Bacteria,1TPIC@1239|Firmicutes,247TB@186801|Clostridia,36EZ3@31979|Clostridiaceae 186801|Clostridia L Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_260377_35 310539.Q5G7M2_9CAUD 1.21e-11 77.4 4QAY9@10239|Viruses,4QWGZ@35237|dsDNA viruses no RNA stage,4QRJC@28883|Caudovirales,4QMNM@10699|Siphoviridae 10699|Siphoviridae S hydrolase activity, acting on acid anhydrides - - - - - - - - - - - - - k59_260377_37 1116375.VEJY3_09500 1.48e-57 188.0 291VY@1|root,2ZPFN@2|Bacteria,1P4BG@1224|Proteobacteria,1SUJ6@1236|Gammaproteobacteria,1XXNJ@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k59_127668_3 644076.SCH4B_4381 3.02e-38 140.0 COG3935@1|root,COG3935@2|Bacteria,1MXB6@1224|Proteobacteria,2U3BK@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DnaD domain protein - - - - - - - - - - - - - k59_334118_2 1122599.AUGR01000011_gene4011 1.62e-43 165.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1QZAD@1224|Proteobacteria,1RYP3@1236|Gammaproteobacteria,1XMG9@135619|Oceanospirillales 135619|Oceanospirillales D nuclear chromosome segregation - - - - - - - - - - - - - k59_54415_2 1692244.A0A0K1RLR5_9CIRC 2.25e-49 166.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_200291_1 1247726.MIM_c10510 5.24e-33 121.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2W3M1@28216|Betaproteobacteria 28216|Betaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_42198_1 1556290.A0A0A0RMB4_9CAUD 7.18e-11 65.1 4QF38@10239|Viruses,4QTDX@28883|Caudovirales,4QMUM@10699|Siphoviridae 10699|Siphoviridae S AAA domain - - - - - - - - - - - - - k59_334122_1 105154.Q9MBU6_9VIRU 1.1e-105 329.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_103242_1 264203.ZMO0380 8.73e-57 205.0 COG3064@1|root,COG3064@2|Bacteria,1R6JV@1224|Proteobacteria,2U5NE@28211|Alphaproteobacteria,2K8S2@204457|Sphingomonadales 204457|Sphingomonadales M Membrane - - - - - - - - - - - - - k59_359488_1 1357275.AVEL02000151_gene1536 1.03e-42 162.0 COG0863@1|root,COG0863@2|Bacteria,1MY4G@1224|Proteobacteria,1RQHA@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.113,2.1.1.72 ko:K00571,ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_165478_1 1476583.DEIPH_ctg052orf0028 5.11e-37 142.0 COG1783@1|root,COG1783@2|Bacteria 2|Bacteria S DNA packaging - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_6 k59_165478_4 1380355.JNIJ01000030_gene5637 2.74e-107 330.0 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1MVH7@1224|Proteobacteria,2TRNA@28211|Alphaproteobacteria,3JW7V@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria KL DNA methylase - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase,ParBc k59_165478_6 1111069.TCCBUS3UF1_11050 4.92e-26 100.0 COG1694@1|root,COG1694@2|Bacteria,1WK7E@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S PFAM MazG nucleotide pyrophosphohydrolase - - - - - - - - - - - - MazG k59_289012_1 243233.MCA2929 2.03e-14 74.3 2EPTJ@1|root,33HE3@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_311610_4 1232428.CAVO010000021_gene805 1.05e-11 73.6 2DBD6@1|root,2Z8I5@2|Bacteria,1UZHS@1239|Firmicutes,4H2J8@909932|Negativicutes 909932|Negativicutes - - - - - - - - - - - - - - Ntox50 k59_348118_2 1122182.KB903833_gene5301 5.61e-11 63.5 COG4570@1|root,COG4570@2|Bacteria,2GV9V@201174|Actinobacteria 201174|Actinobacteria L Endodeoxyribonuclease RusA - - - - - - - - - - - - RusA k59_80710_1 1051675.G0YQG3_9CAUD 7.16e-13 69.3 4QEG2@10239|Viruses,4QVSD@35237|dsDNA viruses no RNA stage,4QRJ9@28883|Caudovirales,4QP0R@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_80710_2 1051675.G0YQF5_9CAUD 1.7e-26 111.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_250660_1 1034115.G1D5L0_9CAUD 5.26e-32 121.0 4QCF5@10239|Viruses,4QV2A@35237|dsDNA viruses no RNA stage,4QPJI@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_371861_1 1788454.A0A190WHE4_9CIRC 9e-44 157.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_274999_1 221360.RS9917_13778 2.98e-17 81.6 COG5055@1|root,COG5055@2|Bacteria,1GPCA@1117|Cyanobacteria,1H2VP@1129|Synechococcus 2|Bacteria L COG5055 Recombination DNA repair protein (RAD52 pathway) - - - ko:K10873 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - DUF968,ERF,Rad52_Rad22 k59_7752_1 1217656.F964_04238 1.96e-42 156.0 COG4626@1|root,COG4626@2|Bacteria,1R2FH@1224|Proteobacteria,1RN1F@1236|Gammaproteobacteria,3NIPD@468|Moraxellaceae 1236|Gammaproteobacteria S Terminase - - - - - - - - - - - - - k59_371867_3 716544.wcw_0671 0.000119 44.7 COG4626@1|root,COG4626@2|Bacteria 2|Bacteria S Terminase - - - - - - - - - - - - Terminase_1 k59_215166_1 856793.MICA_2362 4.9e-05 51.6 COG4447@1|root,COG5295@1|root,COG4447@2|Bacteria,COG5295@2|Bacteria,1NDSM@1224|Proteobacteria,2UK7X@28211|Alphaproteobacteria,4BT5Y@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria UW Chaperone of endosialidase - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - Peptidase_S74 k59_325526_1 1231190.NA8A_18192 2.35e-14 71.6 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2TU8N@28211|Alphaproteobacteria,43KT4@69277|Phyllobacteriaceae 28211|Alphaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_385076_1 1234888.K0A2J2_9VIRU 5.66e-40 153.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_216552_1 330214.NIDE3986 3.46e-26 111.0 COG4626@1|root,COG4626@2|Bacteria 2|Bacteria S Terminase - - - - - - - - - - - - Terminase_1 k59_216552_2 634177.GLX_21440 1.19e-30 127.0 COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria 1224|Proteobacteria S portal protein beeE - - - - - - - - - - - Phage_portal k59_263698_10 875328.JDM601_3424 3.46e-06 57.8 COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,232NN@1762|Mycobacteriaceae 201174|Actinobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II fadD3_2 - 6.2.1.41 ko:K00666,ko:K18687 ko00984,ko01100,ko01120,map00984,map01100,map01120 - R10769 RC00004,RC00014 ko00000,ko00001,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k59_117944_1 1548905.A0A0A1IX16_9CAUD 2.26e-77 243.0 4QBTT@10239|Viruses,4QQUU@28883|Caudovirales,4QKWB@10699|Siphoviridae 10699|Siphoviridae S Phage conserved hypothetical protein BR0599 - - - - - - - - - - - - - k59_337771_2 1304275.C41B8_05408 4.08e-71 225.0 2DVPY@1|root,33WQ8@2|Bacteria,1N9VQ@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_290416_4 348824.LPU83_pLPU83a_0129 1e-24 104.0 COG4227@1|root,COG4227@2|Bacteria,1MU8I@1224|Proteobacteria,2TRIT@28211|Alphaproteobacteria,4B8IY@82115|Rhizobiaceae 28211|Alphaproteobacteria L antirestriction protein - - - - - - - - - - - - DUF1738 k59_70220_2 33898.JRHJ01000076_gene413 9.38e-12 72.0 COG1783@1|root,COG1783@2|Bacteria,2I8SC@201174|Actinobacteria 201174|Actinobacteria S Terminase-like family - - - - - - - - - - - - Terminase_3,Terminase_6,Terminase_6C k59_181446_2 655097.C8ZKH8_9CAUD 3.8e-86 269.0 4QGGR@10239|Viruses,4QZHR@35237|dsDNA viruses no RNA stage,4QUGZ@28883|Caudovirales,4QNY3@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_362403_9 425104.Ssed_4062 8.49e-18 79.7 COG0727@1|root,COG0727@2|Bacteria,1RGTX@1224|Proteobacteria,1S6FY@1236|Gammaproteobacteria,2QC24@267890|Shewanellaceae 1236|Gammaproteobacteria S Putative zinc- or iron-chelating domain - - - ko:K06940 - - - - ko00000 - - - CxxCxxCC k59_35511_1 1379717.S5SY19_9CIRC 3.17e-09 62.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_218690_1 1234888.K0A2J2_9VIRU 6.72e-57 192.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_97159_2 742733.HMPREF9469_05026 3.75e-58 190.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia,221N8@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_97159_5 691965.D4P7D6_9CAUD 1.56e-91 298.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_265536_1 1197951.I6S2A9_9CAUD 1.68e-209 602.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales 28883|Caudovirales S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_230450_2 1379725.S5TMY9_9CIRC 6.93e-37 141.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_189726_5 1498011.A0A096XUT2_9CAUD 2.86e-24 108.0 4QAK6@10239|Viruses,4QRSI@28883|Caudovirales,4QNEJ@10744|Podoviridae 10744|Podoviridae S Pfam:DUF5309 - - - - - - - - - - - - - k59_23464_1 105154.Q9MBU6_9VIRU 4.74e-75 244.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_121425_3 1215092.PA6_046_00270 1.98e-10 57.4 28QDM@1|root,2ZCVZ@2|Bacteria,1P5MR@1224|Proteobacteria,1SW6Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_121425_4 1120970.AUBZ01000070_gene1594 1.46e-41 150.0 2CEG2@1|root,2ZCEX@2|Bacteria,1RB74@1224|Proteobacteria,1S2JC@1236|Gammaproteobacteria,46AFF@72275|Alteromonadaceae 1236|Gammaproteobacteria S Phage replication protein CRI - - - - - - - - - - - - Phage_CRI,Phage_X k59_121473_1 1385658.U5KPZ6_9VIRU 6.36e-59 200.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_388316_6 1234888.K0A2J2_9VIRU 1.89e-161 472.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_388319_2 1165094.RINTHH_3920 5.69e-63 206.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_388319_5 105154.Q9MBU3_9VIRU 5.35e-17 82.4 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_388319_6 1385658.U5KPZ6_9VIRU 1.08e-218 622.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_121506_3 1121441.AUCX01000008_gene2276 1.1e-05 55.1 COG4388@1|root,COG4388@2|Bacteria,1R5B8@1224|Proteobacteria,43B2G@68525|delta/epsilon subdivisions,2X6GH@28221|Deltaproteobacteria,2MC8J@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_388418_2 1618259.A0A0C5I2B5_9CIRC 9.18e-91 278.0 4QE84@10239|Viruses,4QUKR@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_191900_1 237727.NAP1_15673 1.61e-58 186.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2U5BZ@28211|Alphaproteobacteria,2K464@204457|Sphingomonadales 204457|Sphingomonadales L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_191900_3 1304878.AUGD01000002_gene1857 1.92e-27 106.0 2C58H@1|root,32YYI@2|Bacteria,1N7UA@1224|Proteobacteria,2UHCE@28211|Alphaproteobacteria,3K1T7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S NinB protein - - - - - - - - - - - - NinB k59_388423_3 145579.REP_BPPHM 1.35e-20 98.6 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_61065_1 691965.D4P7E6_9CAUD 7.77e-143 465.0 4QAK6@10239|Viruses,4R01K@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_231094_1 1379719.S5TMX6_9CIRC 2.06e-28 121.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_364775_1 1234888.K0A2J2_9VIRU 1.22e-38 145.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_24602_1 1713.JOFV01000024_gene2107 0.000466 48.1 COG0553@1|root,COG0553@2|Bacteria,2GISC@201174|Actinobacteria,4F2SJ@85016|Cellulomonadaceae 201174|Actinobacteria L SNF2 family N-terminal domain - - - - - - - - - - - - HHH_5,Helicase_C,SNF2_N k59_97462_1 1986029.Q9MBM3_9VIRU 1.23e-19 89.4 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_97462_4 1609634.A0A0C5ANA6_9VIRU 6.72e-11 67.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_377003_1 548477.HMPREF0294_0166 8.86e-30 125.0 COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,22K5N@1653|Corynebacteriaceae 201174|Actinobacteria L DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase dnaE2 GO:0000731,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K14162 - - - - ko00000,ko01000,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k59_109640_1 1129794.C427_3733 6.34e-44 149.0 COG1961@1|root,COG1961@2|Bacteria,1R3XB@1224|Proteobacteria,1RSC2@1236|Gammaproteobacteria,466JF@72275|Alteromonadaceae 1236|Gammaproteobacteria L Resolvase, N terminal domain tnpR - - - - - - - - - - - HTH_7,Resolvase k59_121802_4 215158.Q858G7_BPE15 2.48e-21 88.6 4QGFZ@10239|Viruses,4QVJ7@35237|dsDNA viruses no RNA stage,4QU5D@28883|Caudovirales,4QNJN@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_36804_3 662755.CRES_2134 7.48e-09 57.8 COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,22K8T@1653|Corynebacteriaceae 201174|Actinobacteria L Single-stranded DNA-binding protein ssb GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071944,GO:0097159,GO:1901363 - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_279923_1 1122201.AUAZ01000021_gene3149 1.92e-29 119.0 28P6A@1|root,2ZC10@2|Bacteria,1RBZE@1224|Proteobacteria,1RRNS@1236|Gammaproteobacteria,46B6N@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_146152_1 1692249.A0A0K1RLN8_9CIRC 3.43e-22 98.2 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_194790_1 1185876.BN8_01058 1.01e-05 53.1 COG4733@1|root,COG4733@2|Bacteria,4NK2V@976|Bacteroidetes,47P6C@768503|Cytophagia 976|Bacteroidetes G PFAM Fibronectin type III domain - - - - - - - - - - - - fn3 k59_24659_3 1128073.G9LQV6_9CIRC 1.49e-34 135.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_121804_1 314262.MED193_15232 1.49e-05 55.1 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,2P1B5@2433|Roseobacter 28211|Alphaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_279924_1 754035.Mesau_00724 5.05e-32 133.0 2EBXN@1|root,335X0@2|Bacteria,1RCC3@1224|Proteobacteria,2U2ZA@28211|Alphaproteobacteria,43MK2@69277|Phyllobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_316279_3 1380894.S5TR92_9CIRC 2.04e-17 87.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_340471_1 1385658.U5KNR1_9VIRU 4.33e-42 152.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_340471_3 105154.Q9MBU6_9VIRU 3.97e-194 560.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_85581_18 33035.JPJF01000011_gene1265 1.92e-06 57.4 COG4974@1|root,COG4974@2|Bacteria,1TY7M@1239|Firmicutes,24BN9@186801|Clostridia 186801|Clostridia L Psort location Cytoplasmic, score - - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase k59_231574_2 460265.Mnod_6241 6.61e-11 60.8 2ABTE@1|root,3119Z@2|Bacteria,1NP1V@1224|Proteobacteria,2UKGX@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF4054) - - - - - - - - - - - - DUF4054 k59_353243_1 204536.SULAZ_0616 2.62e-21 98.2 COG2404@1|root,COG2404@2|Bacteria,2G567@200783|Aquificae 200783|Aquificae S phosphoesterase, dhha1 - - - - - - - - - - - - DHHA1 k59_732_21 1540092.A0A0A0RPU4_9CAUD 3.52e-18 101.0 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales,4QNG7@10744|Podoviridae 10744|Podoviridae S lytic transglycosylase activity - GO:0008150,GO:0016032,GO:0019058,GO:0030260,GO:0039678,GO:0044403,GO:0044409,GO:0044411,GO:0044419,GO:0046718,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0051830,GO:0085027 - - - - - - - - - - - k59_732_28 326424.FRAAL6246 1.6e-11 73.6 COG4124@1|root,COG4124@2|Bacteria,2GN8K@201174|Actinobacteria 201174|Actinobacteria G Belongs to the glycosyl hydrolase 26 family - - - - - - - - - - - - Glyco_hydro_26 k59_340817_4 118005.AWNK01000007_gene550 2.47e-05 53.5 COG0859@1|root,COG0859@2|Bacteria 2|Bacteria M ADP-heptose-lipopolysaccharide heptosyltransferase activity rfaF - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527,ko:K02841,ko:K02843,ko:K12982 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30,GT9 - Glyco_transf_9 k59_97866_1 1038867.AXAY01000025_gene2044 1.47e-44 156.0 COG5449@1|root,COG5449@2|Bacteria,1PUMI@1224|Proteobacteria,2U66K@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Uncharacterized conserved protein (DUF2163) - - - - - - - - - - - - DUF2163,Phage_BR0599 k59_377471_1 665956.HMPREF1032_00674 2.43e-67 221.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia,3WNJZ@541000|Ruminococcaceae 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_24948_7 2880.D7FLK0 7.54e-06 53.9 KOG3610@1|root,KOG3610@2759|Eukaryota 2759|Eukaryota BQ semaphorin-plexin signaling pathway - - - - - - - - - - - - Laminin_G_3,RasGAP,TIG k59_24948_8 626887.J057_01785 3.26e-69 231.0 2DCM2@1|root,32TZV@2|Bacteria,1NAGE@1224|Proteobacteria,1SMRS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_24948_12 566461.SSFG_01107 3.05e-39 144.0 2BM0G@1|root,32FHD@2|Bacteria,2H28P@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_329785_3 1165094.RINTHH_3920 1.95e-59 197.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_317739_2 1122201.AUAZ01000054_gene2106 6.86e-29 118.0 29YJZ@1|root,30KF8@2|Bacteria,1QJAH@1224|Proteobacteria,1RTSP@1236|Gammaproteobacteria,46C69@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_74612_1 1234888.K0A2J2_9VIRU 5.26e-46 164.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_147430_5 658401.C7F4B8_9CAUD 3.64e-10 70.5 4QH5W@10239|Viruses,4QYFG@35237|dsDNA viruses no RNA stage,4QQD8@28883|Caudovirales,4QN2T@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_147430_6 1304275.C41B8_05368 6.05e-73 255.0 28S81@1|root,2ZEJD@2|Bacteria,1RCNN@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_341700_1 1229205.BUPH_08203 0.000143 49.3 COG1475@1|root,COG1475@2|Bacteria,1ND69@1224|Proteobacteria,2VXCN@28216|Betaproteobacteria,1K5GC@119060|Burkholderiaceae 28216|Betaproteobacteria K Belongs to the ParB family parB - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_244364_2 1788447.A0A190WHJ9_9CIRC 4.49e-104 310.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_208400_2 1609634.A0A0C5AFV4_9VIRU 8.18e-222 630.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_208400_3 105154.Q9MBU3_9VIRU 6.09e-12 67.4 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_13318_1 1123508.JH636442_gene4470 2.71e-06 49.7 COG3087@1|root,COG3087@2|Bacteria,2IX3F@203682|Planctomycetes 203682|Planctomycetes D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - - - - - - - - - - - k59_98796_2 381666.H16_A1852 1.67e-27 110.0 COG3751@1|root,COG3751@2|Bacteria,1RJST@1224|Proteobacteria,2VZZN@28216|Betaproteobacteria,1K9ZI@119060|Burkholderiaceae 28216|Betaproteobacteria O 2OG-Fe(II) oxygenase superfamily - - - - - - - - - - - - 2OG-FeII_Oxy_3 k59_317749_1 378806.STAUR_2852 6.39e-27 114.0 COG4675@1|root,COG4675@2|Bacteria,1QZI2@1224|Proteobacteria,43CJ5@68525|delta/epsilon subdivisions,2X7TG@28221|Deltaproteobacteria,2Z2C8@29|Myxococcales 28221|Deltaproteobacteria S tail collar domain protein - - - - - - - - - - - - - k59_62608_6 1609634.A0A0C5AFT2_9VIRU 1.54e-56 192.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_62608_8 186617.M9M8L2_9VIRU 4.89e-61 203.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_354198_1 1123072.AUDH01000038_gene151 6.73e-26 111.0 COG5281@1|root,COG5281@2|Bacteria,1MX2R@1224|Proteobacteria,2U3WK@28211|Alphaproteobacteria,2JTUX@204441|Rhodospirillales 204441|Rhodospirillales D tape measure protein - - - - - - - - - - - - - k59_366044_1 1005994.GTGU_03336 3.75e-54 185.0 COG3969@1|root,COG3969@2|Bacteria,1NBDM@1224|Proteobacteria,1RYRP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S phosphoadenosine phosphosulfate ybdN - - - - - - - - - - - DUF3440,PAPS_reduct k59_342646_1 691965.D4P7I3_9CAUD 2.14e-142 442.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_111786_2 1609634.A0A0C5ANA6_9VIRU 5.39e-15 77.8 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_183917_1 1089551.KE386572_gene4715 1.62e-46 174.0 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,2TT3N@28211|Alphaproteobacteria,4BRN5@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_99667_1 1089548.KI783301_gene2632 3.5e-18 89.7 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,4H9Z7@91061|Bacilli 91061|Bacilli L DNA polymerase - - - - - - - - - - - - DNA_pol_A k59_379124_2 906888.JCM19314_66 0.000116 43.1 2DNW5@1|root,32ZGI@2|Bacteria,4NT26@976|Bacteroidetes,1I423@117743|Flavobacteriia,3HKQK@363408|Nonlabens 976|Bacteroidetes S Rho termination factor, N-terminal domain - - - - - - - - - - - - Rho_N k59_379124_3 1410634.JHVD01000032_gene417 4.12e-18 85.1 COG4626@1|root,COG4626@2|Bacteria,2IB7D@201174|Actinobacteria,4DWB0@85009|Propionibacteriales 201174|Actinobacteria S Terminase - - - - - - - - - - - - Terminase_3,Terminase_6 k59_51115_1 1379701.JPJC01000229_gene2442 8.14e-05 44.3 2E3EW@1|root,33ISG@2|Bacteria,1MZ6T@1224|Proteobacteria,2UD2B@28211|Alphaproteobacteria,2K5R8@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - k59_160638_1 1692255.A0A0K1RL52_9CIRC 4.87e-47 167.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_148217_1 1385658.U5KPZ6_9VIRU 1.65e-196 565.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_148217_2 1385658.U5KQQ9_9VIRU 2.76e-06 54.7 4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_148217_4 1385658.U5KNR1_9VIRU 2.2e-73 236.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_342707_1 1131814.JAFO01000001_gene1477 7.9e-11 64.3 COG3409@1|root,COG3409@2|Bacteria,1NCJ6@1224|Proteobacteria,2U1UB@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_1 k59_366778_1 1123075.AUDP01000007_gene2789 1.84e-22 97.4 COG0149@1|root,COG0149@2|Bacteria,1UYUE@1239|Firmicutes,248TQ@186801|Clostridia,3WNQQ@541000|Ruminococcaceae 186801|Clostridia G Triosephosphate isomerase - - 5.3.1.1,5.3.1.33 ko:K01803,ko:K21910 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM k59_209610_1 395492.Rleg2_2431 2.38e-85 271.0 COG3567@1|root,COG3567@2|Bacteria,1QNPU@1224|Proteobacteria,2U19C@28211|Alphaproteobacteria,4BA7J@82115|Rhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1073) - - - ko:K09961 - - - - ko00000 - - - DUF1073 k59_294251_1 221360.RS9917_12950 7.25e-39 141.0 COG1442@1|root,COG1442@2|Bacteria,1G3Z0@1117|Cyanobacteria,1GZDJ@1129|Synechococcus 1117|Cyanobacteria M PFAM Glycosyl transferase, family 8 - - - - - - - - - - - - Glyco_transf_8 k59_75485_1 1121289.JHVL01000007_gene2742 2.48e-05 54.3 COG5280@1|root,COG5412@1|root,COG5280@2|Bacteria,COG5412@2|Bacteria,1TPR1@1239|Firmicutes,24NN1@186801|Clostridia,36F0M@31979|Clostridiaceae 186801|Clostridia D tape measure - - - - - - - - - - - - - k59_99758_2 444875.E3SMH9_9CAUD 1.51e-40 147.0 4QAM2@10239|Viruses,4QV3W@35237|dsDNA viruses no RNA stage,4QPGK@28883|Caudovirales,4QNW0@10744|Podoviridae 10744|Podoviridae S exonuclease activity - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - - - - - - - - - - - k59_318912_1 796606.BMMGA3_01825 4.72e-35 134.0 COG1404@1|root,COG1404@2|Bacteria,1TPZ5@1239|Firmicutes,4HA5F@91061|Bacilli,1ZPUP@1386|Bacillus 91061|Bacilli O Belongs to the peptidase S8 family isp - - ko:K13275 - - - - ko00000,ko01000,ko01002,ko03110 - - - Peptidase_S8 k59_124443_1 448385.sce5600 2.83e-59 201.0 COG2304@1|root,COG2304@2|Bacteria,1QZU5@1224|Proteobacteria,43CP6@68525|delta/epsilon subdivisions,2X7WG@28221|Deltaproteobacteria,2YY1I@29|Myxococcales 28221|Deltaproteobacteria S TROVE domain - - - ko:K11089 ko05322,map05322 - - - ko00000,ko00001 - - - TROVE k59_246427_6 1231190.NA8A_23409 4.51e-28 110.0 COG4122@1|root,COG4122@2|Bacteria,1QWQR@1224|Proteobacteria,2TX2B@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Methyltransferase domain - - - - - - - - - - - - Methyltransf_24 k59_332019_1 690850.Desaf_3555 4.81e-10 62.8 COG4675@1|root,COG5301@1|root,COG4675@2|Bacteria,COG5301@2|Bacteria,1N0FZ@1224|Proteobacteria,42TXS@68525|delta/epsilon subdivisions 1224|Proteobacteria S Phage Tail Collar Domain - - - - - - - - - - - - Collar k59_198132_2 428125.CLOLEP_01405 5.24e-34 122.0 2AIHK@1|root,318ZG@2|Bacteria,1V7P0@1239|Firmicutes,24KNU@186801|Clostridia,3WNH7@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_198132_5 411460.RUMTOR_01350 3.05e-12 70.9 2EAAT@1|root,334F2@2|Bacteria,1VJJI@1239|Firmicutes,24TQU@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_39839_1 1415780.JPOG01000001_gene1744 1.77e-26 117.0 COG0454@1|root,COG0827@1|root,COG1040@1|root,COG3087@1|root,COG0456@2|Bacteria,COG0827@2|Bacteria,COG1040@2|Bacteria,COG3087@2|Bacteria,1PI1K@1224|Proteobacteria,1T6BU@1236|Gammaproteobacteria,1XB7I@135614|Xanthomonadales 135614|Xanthomonadales D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - - - - - - - - - - - k59_343871_2 1618260.A0A0C5I2C5_9CIRC 2.53e-86 269.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_367949_1 1458863.A0A088C4W7_9CAUD 8.59e-31 125.0 4QF06@10239|Viruses,4QVMB@35237|dsDNA viruses no RNA stage,4QPRV@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_161864_1 511.JT27_18230 2.5e-88 283.0 2F26G@1|root,33V4S@2|Bacteria,1NUS1@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_210779_1 688245.CtCNB1_1438 1.13e-26 107.0 28J67@1|root,2Z91Y@2|Bacteria,1R7RG@1224|Proteobacteria,2VRTM@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_210779_2 460265.Mnod_6746 4.45e-09 58.2 COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,2VG5E@28211|Alphaproteobacteria,1JV02@119045|Methylobacteriaceae 28211|Alphaproteobacteria H PFAM 6-pyruvoyl tetrahydropterin synthase queD - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS k59_198140_1 1380355.JNIJ01000089_gene2468 1.34e-41 160.0 COG2931@1|root,COG3420@1|root,COG2931@2|Bacteria,COG3420@2|Bacteria,1MU7T@1224|Proteobacteria,2V8VX@28211|Alphaproteobacteria,3K1ZD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q COG2931, RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - - k59_234564_2 883156.HMPREF9282_00941 8.16e-43 163.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H2W4@909932|Negativicutes 909932|Negativicutes L SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_234564_3 938288.HG326225_gene1158 7.82e-07 52.0 2E38J@1|root,32Y88@2|Bacteria,1VAXK@1239|Firmicutes,24N7K@186801|Clostridia 186801|Clostridia S VRR-NUC domain protein - - - - - - - - - - - - VRR_NUC k59_234564_5 3694.POPTR_0018s00860.1 6.74e-10 65.1 COG0749@1|root,KOG0950@2759|Eukaryota,37KZP@33090|Viridiplantae,3G7AS@35493|Streptophyta,4JNSM@91835|fabids 35493|Streptophyta A DNA polymerase - GO:0000018,GO:0000724,GO:0000725,GO:0000726,GO:0002200,GO:0002376,GO:0002377,GO:0002440,GO:0002520,GO:0002566,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003684,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006282,GO:0006284,GO:0006302,GO:0006303,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007275,GO:0008094,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009314,GO:0009416,GO:0009628,GO:0009639,GO:0009640,GO:0009653,GO:0009791,GO:0009888,GO:0009892,GO:0009933,GO:0009987,GO:0010468,GO:0010564,GO:0010569,GO:0010605,GO:0016043,GO:0016445,GO:0016446,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016829,GO:0016835,GO:0016887,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031324,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042623,GO:0042802,GO:0043142,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045738,GO:0045910,GO:0045934,GO:0046483,GO:0048507,GO:0048519,GO:0048523,GO:0048532,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051239,GO:0051259,GO:0051260,GO:0051301,GO:0051575,GO:0051716,GO:0051726,GO:0060255,GO:0065003,GO:0065007,GO:0070013,GO:0071704,GO:0071840,GO:0071897,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0090305,GO:0097159,GO:0097681,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901987,GO:1902749,GO:1990067,GO:2000011,GO:2000026,GO:2000042,GO:2000779,GO:2000780,GO:2001020,GO:2001021 2.7.7.7 ko:K02349 - - - - ko00000,ko01000,ko03400 - - - DEAD,DNA_pol_A,Helicase_C k59_184783_2 1121033.AUCF01000009_gene1201 2.76e-77 239.0 COG1442@1|root,COG1442@2|Bacteria,1QH4S@1224|Proteobacteria,2U2NZ@28211|Alphaproteobacteria,2JTII@204441|Rhodospirillales 204441|Rhodospirillales M glycosyl transferase family 8 - - - - - - - - - - - - - k59_184783_3 444860.E3SJ76_9CAUD 9.25e-64 207.0 4QCFA@10239|Viruses,4QUPF@35237|dsDNA viruses no RNA stage,4QQD7@28883|Caudovirales,4QIYX@10662|Myoviridae 10662|Myoviridae S coenzyme binding - - - - - - - - - - - - - k59_52360_1 1609634.A0A0C5ANA6_9VIRU 2.54e-20 87.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_52360_2 1609634.A0A0C5AFV4_9VIRU 6.57e-111 335.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_39850_1 941449.dsx2_3315 1.81e-35 138.0 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,42QJ2@68525|delta/epsilon subdivisions,2WM78@28221|Deltaproteobacteria,2M8CT@213115|Desulfovibrionales 28221|Deltaproteobacteria S VWA-like domain (DUF2201) - - - - - - - - - - - - DUF2201,DUF2201_N k59_39850_3 134676.ACPL_6932 8.21e-30 111.0 2DXRV@1|root,3467M@2|Bacteria,2IKBE@201174|Actinobacteria,4DDDI@85008|Micromonosporales 201174|Actinobacteria - - - - - - - - - - - - - - - k59_39850_4 134676.ACPL_6931 4.96e-35 135.0 COG4676@1|root,COG4676@2|Bacteria,2GPA6@201174|Actinobacteria,4DCBY@85008|Micromonosporales 201174|Actinobacteria S Protein conserved in bacteria - - - - - - - - - - - - - k59_4020_1 105559.Nwat_3018 1.53e-07 60.1 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,1RXX2@1236|Gammaproteobacteria,1WX24@135613|Chromatiales 135613|Chromatiales S VWA-like domain (DUF2201) - - - - - - - - - - - - DUF2201,DUF2201_N k59_258740_1 76869.PputGB1_1748 5.14e-42 162.0 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,1RZ7H@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_258740_4 194699.Q775C7_BPBPP 3.16e-108 325.0 4QH0X@10239|Viruses,4QXIJ@35237|dsDNA viruses no RNA stage,4QSY6@28883|Caudovirales,4QNTU@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_114077_1 1609634.A0A0C5ANA6_9VIRU 1.34e-24 102.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_77903_1 658172.CKC_03940 4.71e-52 181.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,2U1P9@28211|Alphaproteobacteria,4BDQ9@82115|Rhizobiaceae 28211|Alphaproteobacteria S DNA packaging protein gp2 gp2 - - - - - - - - - - - Terminase_6,Terminase_6C k59_90333_1 360910.BAV0432 5.23e-114 373.0 COG3170@1|root,COG3170@2|Bacteria,1Q45C@1224|Proteobacteria,2W196@28216|Betaproteobacteria 28216|Betaproteobacteria NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - k59_77904_1 164757.Mjls_3895 6.89e-10 63.2 COG0500@1|root,COG2226@2|Bacteria,2GJUF@201174|Actinobacteria,236M1@1762|Mycobacteriaceae 201174|Actinobacteria Q Catalyzes the methylation of the lipid moiety of the intermediate compounds phthiotriol and glycosylated phenolphthiotriol dimycoserosates to form phthiocerol dimycocerosates (DIM A) and glycosylated phenolphthiocerol dimycocerosates (PGL) - - - - - - - - - - - - Methyltransf_11 k59_66051_1 646529.Desaci_1301 2.29e-22 101.0 COG4653@1|root,COG4653@2|Bacteria,1TS6A@1239|Firmicutes,24994@186801|Clostridia,266IV@186807|Peptococcaceae 186801|Clostridia S TIGRFAM phage major capsid protein, HK97 family - - - - - - - - - - - - Phage_capsid k59_224135_1 105154.Q9MBT9_9VIRU 1.26e-05 45.4 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_224135_2 1609634.A0A0C5AFT2_9VIRU 4.41e-91 278.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_333287_4 190650.CC_0199 1.25e-05 54.7 COG4961@1|root,COG4961@2|Bacteria,1NYZQ@1224|Proteobacteria,2TX4T@28211|Alphaproteobacteria,2KHMT@204458|Caulobacterales 204458|Caulobacterales U Putative Flp pilus-assembly TadE/G-like - - - - - - - - - - - - E1_FCCH,Tad k59_296921_2 469610.HMPREF0189_01156 1.64e-22 98.6 COG3723@1|root,COG3723@2|Bacteria,1R6DB@1224|Proteobacteria,2VNV4@28216|Betaproteobacteria 28216|Betaproteobacteria L RecT family recT - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_260089_1 194867.ALBQ01000016_gene3018 1.71e-41 155.0 COG4653@1|root,COG4653@2|Bacteria,1Q3BS@1224|Proteobacteria,2TW86@28211|Alphaproteobacteria,2K50B@204457|Sphingomonadales 204457|Sphingomonadales S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_369332_1 1121445.ATUZ01000011_gene824 0.000962 48.1 COG3170@1|root,COG3170@2|Bacteria,1QZU8@1224|Proteobacteria,43CP9@68525|delta/epsilon subdivisions,2X7WK@28221|Deltaproteobacteria 28221|Deltaproteobacteria NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - k59_16390_1 1089546.AQUI01000002_gene1438 3.43e-06 52.8 COG2242@1|root,COG2242@2|Bacteria,2GMWW@201174|Actinobacteria,4096K@622450|Actinopolysporales 201174|Actinobacteria H Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 k59_41431_2 1379724.S5T6B0_9CIRC 5.03e-80 246.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_41431_4 1692249.A0A0K1RLN8_9CIRC 1.09e-21 90.9 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_323052_2 981369.JQMJ01000003_gene7447 2.1e-39 154.0 COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria,2NEZI@228398|Streptacidiphilus 201174|Actinobacteria L DnaB-like helicase N terminal domain dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3 k59_237183_1 1609634.A0A0C5AFV4_9VIRU 2.06e-112 343.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_358799_1 1095772.CAHH01000063_gene639 3.38e-55 181.0 2EES9@1|root,338JX@2|Bacteria,2H5MY@201174|Actinobacteria 201174|Actinobacteria L RNase_H superfamily - - - - - - - - - - - - RNase_H_2 k59_6864_1 1618248.A0A0C5IB82_9CIRC 1.09e-27 112.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_43061_1 1111730.ATTM01000002_gene1130 7.69e-13 67.8 COG0270@1|root,COG0270@2|Bacteria,4NRFG@976|Bacteroidetes 976|Bacteroidetes L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_43061_2 1120936.KB907208_gene1107 8.12e-153 455.0 COG0209@1|root,COG0209@2|Bacteria,2IC1H@201174|Actinobacteria 201174|Actinobacteria F Ribonucleotide reductase, barrel domain - - - - - - - - - - - - Ribonuc_red_lgC k59_81224_2 314262.MED193_18924 1.95e-20 101.0 2EPTJ@1|root,33HE3@2|Bacteria,1NNYK@1224|Proteobacteria,2UWK5@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_360083_2 1636271.A0A0E3M3Z6_9CAUD 1.06e-57 191.0 4QFVK@10239|Viruses,4QSUR@28883|Caudovirales,4QM8N@10699|Siphoviridae 10699|Siphoviridae S transferase activity - - - - - - - - - - - - - k59_105340_1 502558.EGYY_00600 6.04e-23 99.8 COG0270@1|root,COG0270@2|Bacteria,2HTYU@201174|Actinobacteria,4CWG1@84998|Coriobacteriia 84998|Coriobacteriia L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_19119_1 1609634.A0A0C5AFV4_9VIRU 9.95e-50 175.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_227482_2 1197951.I6RT10_9CAUD 1.26e-26 113.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales 28883|Caudovirales S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_166108_1 344747.PM8797T_26995 1.28e-55 195.0 COG3087@1|root,COG3087@2|Bacteria,2IX3F@203682|Planctomycetes 203682|Planctomycetes D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - - - - - - - - - - - k59_215649_3 399549.Msed_1354 0.000376 43.9 COG1061@1|root,arCOG00877@2157|Archaea,2XPT2@28889|Crenarchaeota 28889|Crenarchaeota K DEAD DEAH box helicase domain protein - - - - - - - - - - - - Helicase_C,ResIII k59_202637_5 1122201.AUAZ01000021_gene3152 4.35e-133 390.0 28W6R@1|root,2ZI7D@2|Bacteria,1N49N@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_202637_8 1122201.AUAZ01000021_gene3149 4.55e-149 452.0 28P6A@1|root,2ZC10@2|Bacteria,1RBZE@1224|Proteobacteria,1RRNS@1236|Gammaproteobacteria,46B6N@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_44811_1 1618236.A0A0C5IB23_9CIRC 3.15e-50 175.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_69474_5 1280681.AUJZ01000037_gene2537 5.67e-63 216.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,4BXUQ@830|Butyrivibrio 186801|Clostridia L Bacterial SNF2 helicase associated - - - - - - - - - - - - Helicase_C,SNF2_N,SNF2_assoc k59_215852_1 420662.Mpe_A0537 2.38e-28 118.0 COG1196@1|root,COG5280@1|root,COG1196@2|Bacteria,COG5280@2|Bacteria 2|Bacteria NT Phage tail tape measure protein TP901 yqbO5 - - ko:K22044 - - - - ko00000,ko02000 1.A.23.3 - - PhageMin_Tail,SLT k59_215852_2 631454.N177_3938 5.85e-22 94.4 COG5448@1|root,COG5448@2|Bacteria,1MXM8@1224|Proteobacteria,2TTJ3@28211|Alphaproteobacteria,1JNXX@119043|Rhodobiaceae 28211|Alphaproteobacteria S Conserved hypothetical protein 2217 (DUF2460) - - - - - - - - - - - - DUF2460 k59_19310_1 1676184.A0A186YBN5_9CIRC 6.35e-35 136.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_154653_2 1788454.A0A190WHE4_9CIRC 6.97e-39 141.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_336901_2 44251.PDUR_27975 2.16e-45 157.0 28MC2@1|root,2ZAQD@2|Bacteria,1VSEU@1239|Firmicutes,4HT1S@91061|Bacilli,271QD@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - k59_179110_2 1165094.RINTHH_3920 1.46e-52 179.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_251321_1 240016.ABIZ01000001_gene824 1.64e-76 258.0 COG0859@1|root,COG0859@2|Bacteria,46TJT@74201|Verrucomicrobia 74201|Verrucomicrobia M Glycosyltransferase family 9 (heptosyltransferase) - - - - - - - - - - - - Glyco_transf_9,Mannosyl_trans3 k59_156471_1 1692252.A0A0K1RL35_9CIRC 2.01e-34 129.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_9937_3 1370121.AUWS01000006_gene5415 3.45e-12 66.2 29WAD@1|root,30HVV@2|Bacteria,2GW9C@201174|Actinobacteria,23DVZ@1762|Mycobacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_253114_2 118166.JH976538_gene5273 6.66e-05 50.1 COG0175@1|root,COG0175@2|Bacteria,1GFFA@1117|Cyanobacteria,1HG6I@1150|Oscillatoriales 1117|Cyanobacteria EH sulfate reduction - - - - - - - - - - - - - k59_46717_1 753085.F4YCV3_9CAUD 8.49e-43 156.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_46717_3 1300005.R9RGD4_9CAUD 9.42e-30 112.0 4QB2U@10239|Viruses,4QVJC@35237|dsDNA viruses no RNA stage,4QTMH@28883|Caudovirales 28883|Caudovirales S Pfam:GTA_holin_3TM - - - - - - - - - - - - - k59_46717_4 233412.HD_0501 2.12e-40 142.0 COG3023@1|root,COG3023@2|Bacteria,1RJ5G@1224|Proteobacteria,1SYPJ@1236|Gammaproteobacteria,1Y8A5@135625|Pasteurellales 135625|Pasteurellales V N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2 k59_302663_1 1331060.RLDS_16020 2.73e-20 91.7 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria,2K42P@204457|Sphingomonadales 204457|Sphingomonadales S Terminase - - - - - - - - - - - - Terminase_1 k59_374384_1 1283283.ATXA01000018_gene4171 4.55e-25 108.0 COG1749@1|root,COG3386@1|root,COG4932@1|root,COG1749@2|Bacteria,COG3386@2|Bacteria,COG4932@2|Bacteria,2I2X3@201174|Actinobacteria,4EUDH@85013|Frankiales 201174|Actinobacteria N Bacterial Ig-like domain - - - - - - - - - - - - Big_5,DUF4082,Mo-co_dimer,fn3 k59_253115_1 570952.ATVH01000019_gene756 1.26e-18 91.7 COG1783@1|root,COG1783@2|Bacteria,1RAGC@1224|Proteobacteria,2U6JF@28211|Alphaproteobacteria,2JSIA@204441|Rhodospirillales 204441|Rhodospirillales S phage Terminase large subunit - - - - - - - - - - - - - k59_34974_1 1101188.KI912155_gene1858 1.92e-12 80.1 COG0739@1|root,COG1196@1|root,COG3941@1|root,COG0739@2|Bacteria,COG1196@2|Bacteria,COG3941@2|Bacteria,2I5RM@201174|Actinobacteria 201174|Actinobacteria D nuclear chromosome segregation - - - - - - - - - - - - - k59_386235_4 1618259.A0A0C5I2B5_9CIRC 2.68e-54 184.0 4QE84@10239|Viruses,4QUKR@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_144034_1 145579.B_BPPHM 8.29e-15 73.2 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_107398_1 247490.KSU1_C0438 2.24e-07 52.4 COG5434@1|root,COG5434@2|Bacteria,2J1BF@203682|Planctomycetes 2|Bacteria M Protein of unknown function (DUF1565) - - - - - - - - - - - - Beta_helix,DUF1565,Pectate_lyase_3 k59_264826_1 1380394.JADL01000006_gene5249 8.21e-20 94.7 28QU5@1|root,2ZD9H@2|Bacteria,1RAU8@1224|Proteobacteria,2VC6Q@28211|Alphaproteobacteria,2JY0A@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_204655_1 1538804.A0A088F6T3_9CAUD 2.71e-38 144.0 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_206026_1 159087.Daro_0797 6.24e-15 72.8 COG3617@1|root,COG3617@2|Bacteria,1N09A@1224|Proteobacteria,2W36F@28216|Betaproteobacteria,2KZMV@206389|Rhodocyclales 206389|Rhodocyclales K BRO family, N-terminal domain - - - - - - - - - - - - Bro-N k59_72779_1 1500893.JQNB01000001_gene341 2.44e-57 182.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,1X5FK@135614|Xanthomonadales 135614|Xanthomonadales L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_266235_1 1121895.Q765_15025 0.000124 43.9 2BRXN@1|root,32KXX@2|Bacteria,4PJ1M@976|Bacteroidetes,1IA76@117743|Flavobacteriia,2NZ18@237|Flavobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - k59_120470_4 1249997.JHZW01000003_gene3734 0.000374 45.8 COG1511@1|root,COG3210@1|root,COG1511@2|Bacteria,COG3210@2|Bacteria,4PKI0@976|Bacteroidetes,1IKUE@117743|Flavobacteriia,2PI31@252356|Maribacter 976|Bacteroidetes U PFAM Collagen triple helix repeat (20 copies) - - - - - - - - - - - - - k59_351997_1 1262449.CP6013_1422 5.37e-08 55.5 COG2189@1|root,COG2189@2|Bacteria,1UHUQ@1239|Firmicutes,25E35@186801|Clostridia,36VST@31979|Clostridiaceae 186801|Clostridia L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_351997_2 649831.L083_0356 2.57e-07 53.5 2DC6Z@1|root,2ZD43@2|Bacteria 2|Bacteria S HNH endonuclease - - - - - - - - - - - - HNH_3 k59_278683_1 948071.S4S2D9_9CAUD 5.51e-137 409.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae 10744|Podoviridae S ribonucleoside-triphosphate reductase activity - - - - - - - - - - - - - k59_266236_2 1385658.U5KPZ6_9VIRU 3.69e-87 273.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_120474_1 1123288.SOV_2c03720 1.59e-14 78.2 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1TPHP@1239|Firmicutes,4H3IW@909932|Negativicutes 1239|Firmicutes KL Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_363352_1 1408324.JNJK01000014_gene1949 2.5e-44 168.0 COG0827@1|root,COG0827@2|Bacteria,1VR0X@1239|Firmicutes,24VE4@186801|Clostridia 186801|Clostridia L Domain of unknown function (DUF4942) - - - - - - - - - - - - DUF4942 k59_363352_2 1524467.IV04_03710 1.22e-18 92.4 COG0582@1|root,COG0582@2|Bacteria,1QZAS@1224|Proteobacteria,1T441@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k59_242478_1 145579.REP_BPPHM 2.09e-17 85.5 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_387871_2 1692257.A0A0K1RL39_9CIRC 1.45e-50 176.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_60610_1 742733.HMPREF9469_05034 8.39e-16 75.1 2EAAT@1|root,334F2@2|Bacteria,1VJJI@1239|Firmicutes,24TQU@186801|Clostridia,223KD@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_278795_1 1294273.roselon_02113 2.56e-32 132.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,2U0EG@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM Phage - - - - - - - - - - - - Terminase_6C k59_109100_1 1234888.K0A2J2_9VIRU 2.51e-70 230.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_134111_2 1234888.K0A2J2_9VIRU 3.75e-136 407.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_97715_1 428125.CLOLEP_01422 2.92e-61 218.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,3WN92@541000|Ruminococcaceae 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_97715_6 742733.HMPREF9469_05023 5.93e-39 138.0 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia,222RY@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_97715_7 742733.HMPREF9469_05026 1.19e-78 242.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia,221N8@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_97715_9 428125.CLOLEP_01413 3.9e-28 105.0 2E2Y0@1|root,32XYV@2|Bacteria,1VD9S@1239|Firmicutes,24PK0@186801|Clostridia,3WPDR@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_97715_10 691965.D4P7D6_9CAUD 2.08e-201 590.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_97715_11 428125.CLOLEP_01411 1.58e-159 463.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia,3WNJZ@541000|Ruminococcaceae 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_97715_12 691965.D4P7C5_9CAUD 0.0 911.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_97715_13 742740.HMPREF9474_02273 5.75e-11 66.2 2EAAT@1|root,334F2@2|Bacteria,1VJJI@1239|Firmicutes,24TQU@186801|Clostridia,223KD@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_49291_1 428125.CLOLEP_01409 3.33e-57 194.0 COG4626@1|root,COG4626@2|Bacteria,1TT9I@1239|Firmicutes,24AFK@186801|Clostridia,3WNF4@541000|Ruminococcaceae 186801|Clostridia S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_49291_2 411460.RUMTOR_01350 7.36e-15 78.2 2EAAT@1|root,334F2@2|Bacteria,1VJJI@1239|Firmicutes,24TQU@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_219459_1 543632.JOJL01000002_gene8009 0.000323 51.2 COG2755@1|root,COG5434@1|root,COG2755@2|Bacteria,COG5434@2|Bacteria,2II7D@201174|Actinobacteria,4D8ZD@85008|Micromonosporales 201174|Actinobacteria M Glycosyl hydrolases family 28 - - - - - - - - - - - - Alpha_L_fucos,CBM_35,F5_F8_type_C,Glyco_hydro_28,Pectate_lyase_3 k59_364968_1 298386.PBPRB1277 2.15e-09 60.5 COG5281@1|root,COG5281@2|Bacteria,1QUCD@1224|Proteobacteria,1T1T2@1236|Gammaproteobacteria 1236|Gammaproteobacteria D tape measure protein - - - - - - - - - - - - Phage_HK97_TLTM,TMP_2,Tape_meas_lam_C k59_364968_2 1125863.JAFN01000001_gene3559 2.7e-08 54.3 2DS6A@1|root,33ERD@2|Bacteria,1Q2WN@1224|Proteobacteria,4328V@68525|delta/epsilon subdivisions,2WXUD@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_85581_24 1449126.JQKL01000006_gene840 8.51e-21 101.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia 186801|Clostridia L DNA polymerase - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_85581_64 1396141.BATP01000029_gene2258 6.88e-28 113.0 2E0FE@1|root,32W1M@2|Bacteria,46TEN@74201|Verrucomicrobia,2IVPU@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_146468_1 428125.CLOLEP_01375 5.83e-96 314.0 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia,3WNBH@541000|Ruminococcaceae 186801|Clostridia S DNA polymerase type-B family - - - - - - - - - - - - - k59_243481_2 1165094.RINTHH_3920 1.14e-44 157.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_49347_4 545694.TREPR_2208 5.23e-14 84.0 COG2604@1|root,COG2604@2|Bacteria,2J5P0@203691|Spirochaetes 203691|Spirochaetes S Protein of unknown function DUF115 - - - - - - - - - - - - MAF_flag10 k59_171174_2 42565.FP66_04595 1.1e-07 53.9 2ER6M@1|root,33IS8@2|Bacteria,1NIM1@1224|Proteobacteria,1SU18@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_171174_3 1158762.KB898038_gene1905 4.58e-37 150.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1R97W@1224|Proteobacteria 1224|Proteobacteria D Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_183023_1 1385658.U5KPZ6_9VIRU 1.02e-83 265.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_231928_1 2003327.CAPSD_BPCHP 6.87e-30 125.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_377904_1 1347368.HG964404_gene5006 0.000113 45.4 COG0338@1|root,COG0338@2|Bacteria,1UBIY@1239|Firmicutes,4HDX1@91061|Bacilli,1ZFS7@1386|Bacillus 91061|Bacilli L D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_74103_4 1121896.JMLU01000052_gene1259 8.94e-26 100.0 COG3108@1|root,COG3108@2|Bacteria,4P9W9@976|Bacteroidetes,1INI1@117743|Flavobacteriia,2NZQD@237|Flavobacterium 976|Bacteroidetes S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k59_243964_2 1986029.Q9MBM3_9VIRU 7.2e-66 216.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_98335_1 1235689.K4PA76_9CAUD 2.6e-51 173.0 4QH0X@10239|Viruses,4QXIJ@35237|dsDNA viruses no RNA stage,4QSY6@28883|Caudovirales,4QNTU@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_159189_1 478749.BRYFOR_08561 2.31e-26 105.0 2BPMG@1|root,32IEH@2|Bacteria,1V9DC@1239|Firmicutes,24MC0@186801|Clostridia 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - - k59_25371_1 1192868.CAIU01000008_gene961 3.78e-13 67.0 COG5377@1|root,COG5377@2|Bacteria,1PTTE@1224|Proteobacteria,2V4IF@28211|Alphaproteobacteria,43QB5@69277|Phyllobacteriaceae 28211|Alphaproteobacteria L YqaJ-like viral recombinase domain - - - - - - - - - - - - YqaJ k59_25371_3 292414.TM1040_0784 1.19e-65 210.0 2C2XN@1|root,32GT6@2|Bacteria,1REZE@1224|Proteobacteria,2U8HW@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM ERF family protein - - - - - - - - - - - - ERF k59_98341_1 1176422.I6R9T0_9CAUD 2.9e-16 82.4 4QFPE@10239|Viruses,4QWZH@35237|dsDNA viruses no RNA stage,4QS3I@28883|Caudovirales,4QN4U@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_353701_2 105154.Q9MBU3_9VIRU 6.62e-05 50.1 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_86128_1 1165094.RINTHH_3920 6.23e-30 120.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_256282_1 1618248.A0A0C5IB82_9CIRC 1.16e-72 231.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_159246_3 1676988.A0A0H4FV52_9CIRC 1.4e-07 59.3 4QGVY@10239|Viruses,4QUKN@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_122848_2 9778.XP_004372564.1 0.000989 48.9 KOG1584@1|root,KOG1584@2759|Eukaryota,394HT@33154|Opisthokonta,3BI89@33208|Metazoa,3CWR8@33213|Bilateria,483TN@7711|Chordata,48V69@7742|Vertebrata,3JF26@40674|Mammalia,34XW6@311790|Afrotheria 33208|Metazoa S Amine sulfotransferase-like - GO:0003674,GO:0003824,GO:0004062,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008146,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0034930,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0051923 2.8.2.1,2.8.2.2,2.8.2.3,2.8.2.4 ko:K01014,ko:K01015,ko:K01016,ko:K01025,ko:K16949 ko00140,ko05204,map00140,map05204 - R00629,R01242,R01861,R02350,R03405,R08977,R08978 RC00007,RC00128,RC00231,RC00341,RC00610 ko00000,ko00001,ko01000 - - - Sulfotransfer_1 k59_207868_2 488538.SAR116_0382 1.66e-27 122.0 28S81@1|root,2ZEJD@2|Bacteria,1RCNN@1224|Proteobacteria,2U6Z0@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_1230_1 1206739.BAGJ01000270_gene2576 8.59e-29 115.0 28HRJ@1|root,2Z7YZ@2|Bacteria,2GKNT@201174|Actinobacteria,4FW7M@85025|Nocardiaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_98916_1 1123057.P872_18430 9.33e-10 65.9 29YBT@1|root,30K65@2|Bacteria,4NY8W@976|Bacteroidetes,47SZM@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_196157_3 931626.Awo_c35500 3.43e-13 69.3 COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,24HF9@186801|Clostridia,25WQN@186806|Eubacteriaceae 186801|Clostridia L Single-stranded DNA-binding protein ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_62747_1 1220601.L7TJ68_9CAUD 3.43e-36 127.0 4QASP@10239|Viruses,4QVR8@35237|dsDNA viruses no RNA stage,4QR4Z@28883|Caudovirales 28883|Caudovirales S deoxyribonuclease IV (phage-T4-induced) activity - - - - - - - - - - - - - k59_183405_1 1410634.JHVD01000028_gene2099 2.17e-12 67.0 COG4570@1|root,COG4570@2|Bacteria,2GV9V@201174|Actinobacteria 201174|Actinobacteria L Endodeoxyribonuclease RusA - - - - - - - - - - - - RusA k59_232538_1 1609634.A0A0C5AFV4_9VIRU 1.27e-148 437.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_147519_3 1385658.U5KPZ6_9VIRU 5.62e-127 383.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_341846_1 1150990.H6WYG5_9CAUD 6.66e-17 86.7 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_268994_2 1385658.U5KPZ6_9VIRU 7.33e-40 154.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_293539_1 1304880.JAGB01000002_gene2420 1.76e-14 78.6 COG2812@1|root,COG2812@2|Bacteria,1VCQC@1239|Firmicutes,248U4@186801|Clostridia 186801|Clostridia L 'dna polymerase iii holB - 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C k59_293539_2 1128398.Curi_c09890 6.73e-14 79.7 COG0749@1|root,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,267MY@186813|unclassified Clostridiales 186801|Clostridia L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_98993_1 1173762.S4TRS0_9CAUD 2.07e-30 116.0 4QDXM@10239|Viruses,4QWIX@35237|dsDNA viruses no RNA stage,4QQF6@28883|Caudovirales,4QNXH@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_256960_2 105154.Q9MBU6_9VIRU 6.08e-224 636.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_256960_3 105154.Q9MBT9_9VIRU 9.2e-08 53.1 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_13346_1 156889.Mmc1_2604 1.06e-68 226.0 COG1475@1|root,COG4725@1|root,COG1475@2|Bacteria,COG4725@2|Bacteria,1R553@1224|Proteobacteria,2TRP6@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT Belongs to the MT-A70-like family - - - - - - - - - - - - MT-A70 k59_13346_2 571166.KI421509_gene3812 1.96e-30 115.0 28PMA@1|root,2ZCAD@2|Bacteria,1RARQ@1224|Proteobacteria,2U6X3@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_183478_1 864069.MicloDRAFT_00064680 1.64e-33 127.0 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,2TV42@28211|Alphaproteobacteria,1JWXQ@119045|Methylobacteriaceae 28211|Alphaproteobacteria S terminase, large subunit - - - ko:K06909 - - - - ko00000 - - - Terminase_3 k59_256962_1 1524881.A0A088CQ10_9CAUD 8.34e-08 60.8 4QB1J@10239|Viruses,4QRYQ@28883|Caudovirales,4QNIY@10744|Podoviridae 10744|Podoviridae S Pfam:Inj_translocase - GO:0006810,GO:0008150,GO:0016032,GO:0019058,GO:0030260,GO:0039678,GO:0044403,GO:0044409,GO:0044419,GO:0044766,GO:0046718,GO:0046794,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0099002,GO:1902579 - - - - - - - - - - - k59_354328_2 1234888.K0A2J2_9VIRU 4.65e-75 242.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_209396_8 870187.Thini_0817 1.61e-06 55.8 COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,1RNHY@1236|Gammaproteobacteria,45ZTV@72273|Thiotrichales 72273|Thiotrichales O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG k59_136091_1 525904.Tter_0906 2.24e-75 243.0 COG0606@1|root,COG0606@2|Bacteria,2NNW7@2323|unclassified Bacteria 2|Bacteria O Magnesium chelatase, subunit ChlI C-terminal comM - - ko:K06400,ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C k59_330778_1 136993.KB900626_gene2756 2.39e-07 55.1 COG2369@1|root,COG2369@2|Bacteria 2|Bacteria K cell adhesion yqbB3 - - - - - - - - - - - Phage_Mu_F,Phage_portal k59_330778_3 294631.Q5ZGF6_9CAUD 1.77e-119 358.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0019012,GO:0019028,GO:0042802,GO:0044423 - - - - - - - - - - - k59_330778_12 1327981.S0A1R5_9CAUD 8.18e-25 118.0 4QGUS@10239|Viruses,4QX38@35237|dsDNA viruses no RNA stage,4QRVV@28883|Caudovirales,4QN8J@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_233279_1 1609634.A0A0C5ANA6_9VIRU 4.14e-13 71.6 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_196992_12 1089552.KI911559_gene1254 6.52e-13 73.6 COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,2TR01@28211|Alphaproteobacteria,2JQKE@204441|Rhodospirillales 204441|Rhodospirillales O Molecular chaperone cbpA - - - - - - - - - - - DnaJ,DnaJ_C k59_160578_1 460265.Mnod_4078 4.62e-29 123.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria,1JZ7Y@119045|Methylobacteriaceae 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_257603_2 42565.FP66_04570 5.33e-90 279.0 29UKS@1|root,30FY7@2|Bacteria,1RGKW@1224|Proteobacteria,1SKMS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_136093_1 1676988.A0A0H4FNQ1_9CIRC 2.17e-27 112.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_136093_2 1618236.A0A0C5I2F3_9CIRC 8.28e-47 170.0 4QGVY@10239|Viruses,4QUKN@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_245230_2 1204526.K4I0A0_9CAUD 6.43e-38 145.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_63523_1 1096546.WYO_0201 2.49e-108 336.0 28P6A@1|root,2ZC10@2|Bacteria,1RBZE@1224|Proteobacteria,2UQEG@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_257607_1 1618238.A0A0C5IB41_9CIRC 1.86e-05 51.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_197003_1 313596.RB2501_01425 3.09e-68 227.0 COG5545@1|root,COG5545@2|Bacteria,4PMA3@976|Bacteroidetes,1IJP7@117743|Flavobacteriia 976|Bacteroidetes L VirE N-terminal domain - - - - - - - - - - - - DUF3987,PriCT_2,VirE,VirE_N k59_282805_1 1234888.K0A2J2_9VIRU 8.66e-28 115.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_379080_1 391038.Bphy_3396 8.7e-16 78.6 COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,2VRW1@28216|Betaproteobacteria,1K380@119060|Burkholderiaceae 28216|Betaproteobacteria S phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_379080_2 1090320.KB900605_gene3206 6.55e-18 84.0 COG3740@1|root,COG3740@2|Bacteria,1N2D8@1224|Proteobacteria,2U9KB@28211|Alphaproteobacteria,2KCU4@204457|Sphingomonadales 204457|Sphingomonadales S Caudovirus prohead serine protease - - - - - - - - - - - - Peptidase_S78 k59_379188_2 1283077.M1HLI2_9CAUD 4.16e-21 95.5 4QC24@10239|Viruses,4QZPR@35237|dsDNA viruses no RNA stage,4QRZK@28883|Caudovirales,4QP0N@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_367131_1 1379719.S5TMX6_9CIRC 4.67e-20 90.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_343032_1 1403819.BATR01000081_gene2366 6.66e-43 167.0 COG0503@1|root,COG3170@1|root,COG0503@2|Bacteria,COG3170@2|Bacteria 2|Bacteria NU translation initiation factor activity apt - 2.4.2.7 ko:K00759,ko:K20541 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko02000,ko04147 4.D.3.1.6 - - Pribosyltran k59_222087_2 186617.M9M8L2_9VIRU 3.24e-98 299.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_222092_13 243365.CV_1315 8.15e-07 57.8 COG3409@1|root,COG3409@2|Bacteria,1RAYU@1224|Proteobacteria,2VPG4@28216|Betaproteobacteria,2KSB3@206351|Neisseriales 206351|Neisseriales M N-acetylmuramidase - - - - - - - - - - - - Muraidase,PG_binding_1 k59_222092_14 224911.27352791 1.54e-08 58.2 COG0817@1|root,COG0817@2|Bacteria,1NDKU@1224|Proteobacteria,2UFCY@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC - 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - - k59_222092_16 1463825.JNXC01000023_gene4913 6.87e-08 54.7 2CC1Y@1|root,32S23@2|Bacteria,2IQS5@201174|Actinobacteria,4E4SU@85010|Pseudonocardiales 201174|Actinobacteria K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA wblB - - ko:K18955 - - - - ko00000,ko03000 - - - Whib k59_112287_1 1234888.K0A2J2_9VIRU 1.41e-39 146.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_112287_2 1234888.K0A2R8_9VIRU 8.9e-40 144.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_39127_2 1234888.K0A2J2_9VIRU 7.16e-40 146.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_343081_1 871968.DESME_08930 8.95e-22 103.0 2E2CM@1|root,32XHK@2|Bacteria,1VCFP@1239|Firmicutes,24Q3M@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_380301_1 428125.CLOLEP_01400 2.43e-147 454.0 28JED@1|root,2Z98K@2|Bacteria,1TW1U@1239|Firmicutes,24CFD@186801|Clostridia,3WNW0@541000|Ruminococcaceae 186801|Clostridia K Bacterial regulatory proteins, luxR family - - - - - - - - - - - - GerE k59_198062_1 1165094.RINTHH_3920 6.29e-35 134.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_198063_1 1385658.U5KPZ6_9VIRU 8.43e-68 225.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_149403_1 105154.Q9MBU6_9VIRU 2.4e-114 351.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_319910_1 864702.OsccyDRAFT_1343 1.76e-11 72.0 COG0739@1|root,COG0739@2|Bacteria,1G1GS@1117|Cyanobacteria,1H8FP@1150|Oscillatoriales 1117|Cyanobacteria M PFAM Peptidase family M23 - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - LysM,Peptidase_M23 k59_14941_2 997346.HMPREF9374_1109 1.63e-13 75.9 COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4I2FD@91061|Bacilli,27C8I@186824|Thermoactinomycetaceae 91061|Bacilli S Phage tail tape measure protein, TP901 family - - - - - - - - - - - - - k59_198066_1 2003327.CAPSD_BPCHP 1.09e-45 166.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_284235_1 1234888.K0A2J2_9VIRU 4.32e-130 393.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_367865_1 1132509.C447_02857 1.58e-07 55.1 COG1573@1|root,arCOG00905@2157|Archaea,2XUVI@28890|Euryarchaeota,23RZ0@183963|Halobacteria 183963|Halobacteria L Uracil-DNA glycosylase udg1 - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_367915_1 476272.RUMHYD_01966 7.68e-18 77.0 2EK5K@1|root,33DW0@2|Bacteria,1UU54@1239|Firmicutes,255II@186801|Clostridia 186801|Clostridia S Putative phage holin Dp-1 - - - - - - - - - - - - Phage_holin_Dp1 k59_76549_1 1144310.PMI07_002360 3.53e-10 65.1 2DPZ1@1|root,3340X@2|Bacteria,1R2EE@1224|Proteobacteria,2TZIB@28211|Alphaproteobacteria,4BP2Q@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_356048_1 402612.FP2177 1.68e-21 99.4 COG0714@1|root,COG0714@2|Bacteria,4NJMT@976|Bacteroidetes,1HZMP@117743|Flavobacteriia 976|Bacteroidetes S AAA domain (dynein-related subfamily) - - 6.6.1.2 ko:K09882 ko00860,ko01100,map00860,map01100 - R05227 RC02000 ko00000,ko00001,ko01000 - - - AAA_5 k59_270843_1 1609634.A0A0C5AFV4_9VIRU 1.63e-48 174.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_380349_1 260827.Q6R6B4_9CAUD 7.31e-92 290.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales,4QNDH@10744|Podoviridae 10744|Podoviridae S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_173884_1 1234888.K0A2J2_9VIRU 4e-65 218.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_198811_1 742733.HMPREF9469_05020 4.47e-48 174.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,221IX@1506553|Lachnoclostridium 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_381159_2 398767.Glov_0494 9.38e-22 90.1 2DPB2@1|root,331BY@2|Bacteria,1NBDA@1224|Proteobacteria,42VNW@68525|delta/epsilon subdivisions,2WSXY@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_320754_1 2003327.CAPSD_BPCHP 1.06e-25 114.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_247361_3 105154.Q9MBU6_9VIRU 2.84e-110 336.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_368663_1 1165094.RINTHH_3920 1.07e-55 185.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_344647_3 1120963.KB894514_gene389 2.43e-52 192.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,1S4YH@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_344647_4 49964.Q94MS4_9CAUD 1.68e-144 443.0 4QCUF@10239|Viruses,4QV7U@35237|dsDNA viruses no RNA stage,4QQ89@28883|Caudovirales,4QNCY@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_344647_8 49964.Q94MS1_9CAUD 1.76e-130 381.0 4QB4H@10239|Viruses,4QYQI@35237|dsDNA viruses no RNA stage,4QUAR@28883|Caudovirales,4QNUV@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_211586_1 1385658.U5KPZ6_9VIRU 1.83e-79 252.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_356810_3 439235.Dalk_1957 2.52e-24 98.2 2DDKV@1|root,32U1R@2|Bacteria,1N5SP@1224|Proteobacteria,431GY@68525|delta/epsilon subdivisions,2WWIM@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_235234_1 654929.REP_PCV1C 2e-29 121.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_28990_1 1385658.U5KPZ6_9VIRU 6.42e-65 214.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_247442_3 1618247.A0A0C5I2K0_9CIRC 4.2e-09 60.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_198957_1 1385658.U5KPZ6_9VIRU 6.19e-74 240.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_321397_3 258052.JNYV01000001_gene448 8.27e-25 101.0 COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,2M2SY@2063|Kitasatospora 201174|Actinobacteria F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase k59_321397_4 990285.RGCCGE502_13189 3.85e-18 91.3 COG1573@1|root,COG1573@2|Bacteria,1MW8T@1224|Proteobacteria,2TSAR@28211|Alphaproteobacteria,4BD94@82115|Rhizobiaceae 28211|Alphaproteobacteria L uracil-DNA glycosylase - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - DUF4130,UDG k59_296853_1 314232.SKA53_15116 3.34e-08 61.6 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,2P8F6@245186|Loktanella 28211|Alphaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_345356_4 1357732.A0A059PYD9_9CAUD 4.93e-18 90.9 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_321398_1 1205680.CAKO01000006_gene3229 9.39e-27 111.0 2C9JF@1|root,32RPD@2|Bacteria,1N8CG@1224|Proteobacteria,2UNF7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S ERF superfamily - - - - - - - - - - - - ERF k59_78037_1 1986029.Q9MBM3_9VIRU 2.88e-41 146.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_369248_1 1609634.A0A0C5AFT2_9VIRU 2.92e-126 371.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_369248_3 1609634.A0A0C5AFV4_9VIRU 1.19e-266 744.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_369248_5 1609634.A0A0C5ANA6_9VIRU 4.17e-50 169.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_114315_4 105154.Q9MBU6_9VIRU 2.37e-91 288.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_224396_1 948071.S4S2D9_9CAUD 4.33e-105 325.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae 10744|Podoviridae S ribonucleoside-triphosphate reductase activity - - - - - - - - - - - - - k59_260142_1 1123368.AUIS01000020_gene1078 2.46e-29 114.0 28XPA@1|root,2ZJK5@2|Bacteria,1P9T2@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_78222_1 1028800.RG540_CH13740 9.4e-41 152.0 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,2TVEI@28211|Alphaproteobacteria,4BIH2@82115|Rhizobiaceae 28211|Alphaproteobacteria L DNA polymerase A domain - - - - - - - - - - - - DNA_pol_A k59_286321_2 182851.I4AZF8_9CAUD 3e-06 53.5 4QFNJ@10239|Viruses,4R06Z@35237|dsDNA viruses no RNA stage,4QPYH@28883|Caudovirales,4QM57@10699|Siphoviridae 10699|Siphoviridae S intein-mediated protein splicing - - - - - - - - - - - - - k59_185779_2 1609634.A0A0C5ANA6_9VIRU 9.61e-20 90.9 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_185779_3 1609634.A0A0C5AFV4_9VIRU 4.02e-18 83.2 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_163434_1 428125.CLOLEP_01400 3.71e-193 579.0 28JED@1|root,2Z98K@2|Bacteria,1TW1U@1239|Firmicutes,24CFD@186801|Clostridia,3WNW0@541000|Ruminococcaceae 186801|Clostridia K Bacterial regulatory proteins, luxR family - - - - - - - - - - - - GerE k59_30662_2 478749.BRYFOR_08520 3.49e-25 98.2 2E2Y0@1|root,32XYV@2|Bacteria,1VD9S@1239|Firmicutes,24PK0@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_30662_3 691965.D4P7D6_9CAUD 2.42e-168 507.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_30662_4 691965.D4P7D3_9CAUD 2.72e-155 453.0 4QAYV@10239|Viruses,4QUZ7@35237|dsDNA viruses no RNA stage,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - k59_30662_6 742740.HMPREF9474_02273 0.000151 49.7 2EAAT@1|root,334F2@2|Bacteria,1VJJI@1239|Firmicutes,24TQU@186801|Clostridia,223KD@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_67036_3 1449976.KALB_344 0.000124 47.0 COG1840@1|root,COG1840@2|Bacteria,2GUQY@201174|Actinobacteria 201174|Actinobacteria P serine threonine protein kinase - - - - - - - - - - - - - k59_287225_1 691965.D4P7L3_9CAUD 2.5e-134 402.0 4QBH7@10239|Viruses,4QWWF@35237|dsDNA viruses no RNA stage,4QQ8R@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_42379_1 1692244.A0A0K1RLR5_9CIRC 3.98e-49 166.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_248931_1 1385658.U5KPZ6_9VIRU 8.53e-75 242.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_139732_1 1038858.AXBA01000002_gene3715 2.72e-17 85.5 COG0740@1|root,COG0740@2|Bacteria,1MUQ9@1224|Proteobacteria,2U37W@28211|Alphaproteobacteria,3F1GP@335928|Xanthobacteraceae 28211|Alphaproteobacteria OU Clp protease - - - - - - - - - - - - CLP_protease k59_225242_1 420324.KI911970_gene1450 1.06e-51 182.0 28MSK@1|root,2ZB0X@2|Bacteria,1R7CY@1224|Proteobacteria,2U2MY@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_54602_1 698440.XP_007291271.1 1.09e-06 58.2 28KDY@1|root,2QSUT@2759|Eukaryota,38FTA@33154|Opisthokonta,3NZBR@4751|Fungi,3QKR5@4890|Ascomycota 4751|Fungi G Pectate lyase - - - - - - - - - - - - Beta_helix,CBM_1,Chondroitinas_B k59_358146_5 1234888.K0A2J2_9VIRU 7.14e-69 229.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_30684_1 1327036.R4JHP8_9CAUD 5.14e-39 143.0 4QCEF@10239|Viruses,4QVWZ@35237|dsDNA viruses no RNA stage,4QTBA@28883|Caudovirales,4QMGR@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_260759_2 68170.KL590484_gene7712 3.2e-05 51.2 COG0438@1|root,COG0438@2|Bacteria,2GK9J@201174|Actinobacteria,4DX75@85010|Pseudonocardiales 201174|Actinobacteria M PFAM Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 k59_346303_1 1123279.ATUS01000005_gene3110 5.43e-99 319.0 COG1196@1|root,COG2911@1|root,COG1196@2|Bacteria,COG2911@2|Bacteria 2|Bacteria S protein secretion sca1 - - - - - - - - - - - Autotransporter,DUF4114,SLT,Tape_meas_lam_C,VPEP k59_79846_1 1692242.A0A0K1RKZ2_9CIRC 1.64e-12 72.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_249855_1 1692244.A0A0K1RLR5_9CIRC 1.85e-43 151.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_31429_1 945083.E7EKU2_9CAUD 2.24e-10 62.4 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_347193_1 1197906.CAJQ02000016_gene198 5.08e-05 51.6 28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TURR@28211|Alphaproteobacteria,3JUCC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_382978_8 633149.Bresu_1398 0.000613 49.7 2DSRK@1|root,33H6U@2|Bacteria,1P21N@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_261527_2 428127.EUBDOL_01512 2.61e-29 120.0 COG3935@1|root,COG3935@2|Bacteria,1UJYF@1239|Firmicutes 1239|Firmicutes L DnaD domain protein - - - - - - - - - - - - - k59_140595_1 691965.D4P7I3_9CAUD 1.94e-70 239.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_104102_5 1121921.KB898707_gene967 3.59e-36 129.0 2CIEP@1|root,3394E@2|Bacteria,1NFVU@1224|Proteobacteria,1SCD0@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_104102_13 563192.HMPREF0179_00147 2.73e-46 166.0 28JXH@1|root,2ZA3Z@2|Bacteria,1R8CZ@1224|Proteobacteria,42WKC@68525|delta/epsilon subdivisions,2WUAM@28221|Deltaproteobacteria,2MEKQ@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_104102_14 749222.Nitsa_0219 2.41e-18 90.1 2DBI5@1|root,2Z9EN@2|Bacteria,1PMHG@1224|Proteobacteria,42PJZ@68525|delta/epsilon subdivisions,2YN9T@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria L PDDEXK-like domain of unknown function (DUF3799) - - - - - - - - - - - - DUF3799 k59_104102_23 1217703.F904_00992 7.56e-12 75.5 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RMJ1@1236|Gammaproteobacteria,3NK1J@468|Moraxellaceae 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase k59_104102_37 1121434.AULY01000006_gene624 2.99e-10 61.2 COG0286@1|root,COG0286@2|Bacteria,1R0UT@1224|Proteobacteria 1224|Proteobacteria V site-specific DNA-methyltransferase (adenine-specific) activity - - - - - - - - - - - - - k59_104102_38 1434929.X946_345 0.000854 51.2 COG4675@1|root,COG5301@1|root,COG4675@2|Bacteria,COG5301@2|Bacteria,1QXR0@1224|Proteobacteria,2VXXI@28216|Betaproteobacteria,1KIQ3@119060|Burkholderiaceae 28216|Betaproteobacteria S tail collar domain protein - - - - - - - - - - - - - k59_104102_43 1082931.KKY_707 4.45e-38 157.0 COG5283@1|root,COG5283@2|Bacteria,1R5FU@1224|Proteobacteria,2VFQ8@28211|Alphaproteobacteria,3N7TR@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ - - - - - - - - - - - - - k59_214330_1 1052684.PPM_2649 1.23e-07 57.0 COG4373@1|root,COG4373@2|Bacteria,1TQNK@1239|Firmicutes,4HDES@91061|Bacilli,26WPR@186822|Paenibacillaceae 91061|Bacilli S Mu-like prophage FluMu protein gp28 - - - - - - - - - - - - Terminase_6,Terminase_6C k59_68697_2 2850.Phatr47174 2.97e-09 63.2 2CYAC@1|root,2S35N@2759|Eukaryota,2XGMQ@2836|Bacillariophyta 2836|Bacillariophyta S Methyltransferase domain - - - - - - - - - - - - Methyltransf_24 k59_238203_2 1086011.HJ01_03282 3.24e-16 84.0 28HEE@1|root,2Z7QU@2|Bacteria,4NDYE@976|Bacteroidetes,1HZS0@117743|Flavobacteriia,2NTQN@237|Flavobacterium 976|Bacteroidetes S Alpha beta hydrolase - - - - - - - - - - - - DUF932 k59_18679_1 1121447.JONL01000012_gene3405 3.46e-115 387.0 COG0503@1|root,COG2518@1|root,COG0503@2|Bacteria,COG2518@2|Bacteria 2|Bacteria O Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins apt - 2.1.1.163,2.1.1.201,2.1.1.77,2.4.2.7 ko:K00573,ko:K00759,ko:K03183,ko:K07003 ko00130,ko00230,ko01100,ko01110,map00130,map00230,map01100,map01110 M00116,M00117 R00190,R01229,R04378,R04990,R04993,R06859,R08774,R09736 RC00003,RC00063,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000,ko04147 - - - DUF3560,Methyltransf_21,Pribosyltran k59_153934_1 904144.AEJD01000006_gene558 4.11e-58 204.0 COG4626@1|root,COG4626@2|Bacteria,2GM6F@201174|Actinobacteria,4D088@85004|Bifidobacteriales 201174|Actinobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_32431_1 1564096.A0A0A0YXC5_9CAUD 1.06e-33 134.0 4QAUT@10239|Viruses,4QQ7X@28883|Caudovirales,4QIGV@10662|Myoviridae 10662|Myoviridae S DNA ligase (ATP) activity - - - - - - - - - - - - - k59_371930_1 411460.RUMTOR_01335 1.21e-65 226.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_44124_1 521674.Plim_2641 0.000155 46.2 2E3Q3@1|root,32YN2@2|Bacteria,2J0W4@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_141427_2 1229783.C273_01755 2.47e-08 53.9 COG1403@1|root,COG1403@2|Bacteria,1VH3I@1239|Firmicutes,4HPWS@91061|Bacilli,4GZVK@90964|Staphylococcaceae 91061|Bacilli L HNH nucleases - - - - - - - - - - - - HNH k59_104926_1 742740.HMPREF9474_02303 4.1e-172 535.0 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia,221YV@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_44125_1 656519.Halsa_2025 6.7e-05 48.5 COG1475@1|root,COG1475@2|Bacteria,1VTIA@1239|Firmicutes,24YNJ@186801|Clostridia,3WB9J@53433|Halanaerobiales 186801|Clostridia K Belongs to the ParB family - - - - - - - - - - - - ParBc k59_359757_1 1986029.Q9MBM8_9VIRU 9.55e-44 159.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_359757_3 1165094.RINTHH_3920 7.68e-41 149.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_227073_1 186617.M9M8L2_9VIRU 2.43e-46 170.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_32437_2 1165094.RINTHH_3920 7.1e-82 257.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_178407_2 1304275.C41B8_09081 4.73e-36 124.0 COG3668@1|root,COG3668@2|Bacteria,1N9UE@1224|Proteobacteria,1SCS6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S ParE toxin of type II toxin-antitoxin system, parDE - - - - - - - - - - - - ParE_toxin k59_178407_3 1458427.BAWN01000013_gene832 1.46e-10 58.9 29X8U@1|root,30IY7@2|Bacteria,1PYI3@1224|Proteobacteria,2WDQF@28216|Betaproteobacteria,4AIR8@80864|Comamonadaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_178407_4 381666.H16_A2471 4.64e-34 120.0 2F5MN@1|root,33Y6R@2|Bacteria,1NWTV@1224|Proteobacteria,2W2Y7@28216|Betaproteobacteria,1KDVV@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_188105_1 1379719.S5TMX6_9CIRC 1.92e-28 117.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_188105_2 1618247.A0A0C5IMK7_9CIRC 0.000108 50.4 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_360478_1 1096546.WYO_4111 1.05e-20 92.4 2EK50@1|root,33DVF@2|Bacteria,1NK6R@1224|Proteobacteria,2TYQN@28211|Alphaproteobacteria,1JZK7@119045|Methylobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_188107_1 667014.Thein_0681 4.13e-06 55.5 COG4974@1|root,COG4974@2|Bacteria,2GHNW@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria L Belongs to the 'phage' integrase family. XerC subfamily xerC - - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k59_216239_1 411460.RUMTOR_01333 0.000428 44.7 28K55@1|root,2Z9TX@2|Bacteria,1V0P7@1239|Firmicutes,24DCX@186801|Clostridia,3Y0KI@572511|Blautia 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - Sipho_Gp37 k59_203163_2 1609634.A0A0C5AFT2_9VIRU 9.91e-100 304.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_263498_1 1096546.WYO_0201 5.97e-51 182.0 28P6A@1|root,2ZC10@2|Bacteria,1RBZE@1224|Proteobacteria,2UQEG@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_8642_4 546275.FUSPEROL_02001 9.15e-29 108.0 COG3108@1|root,COG3108@2|Bacteria,37ATH@32066|Fusobacteria 32066|Fusobacteria S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Peptidase_M15_4 k59_290048_2 69279.BG36_20805 1.34e-28 123.0 2AA25@1|root,30ZAV@2|Bacteria,1PM8F@1224|Proteobacteria,2UZVR@28211|Alphaproteobacteria,43QIT@69277|Phyllobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_203167_1 1609634.A0A0C5AFV4_9VIRU 2.86e-33 131.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_33542_7 223283.PSPTO_3416 1.9e-12 65.1 2DQAD@1|root,335M3@2|Bacteria,1QV8I@1224|Proteobacteria,1T29X@1236|Gammaproteobacteria,1Z7XP@136849|Pseudomonas syringae group 1236|Gammaproteobacteria S Phage holin family (Lysis protein S) - - - - - - - - - - - - Phage_holin_3_1 k59_203290_1 351607.Acel_0634 4.75e-11 62.8 COG2120@1|root,COG2120@2|Bacteria,2HTX7@201174|Actinobacteria,4EVBT@85013|Frankiales 201174|Actinobacteria S GlcNAc-PI de-N-acetylase - - - - - - - - - - - - PIG-L k59_251735_1 322855.Q52PS6_9CAUD 4.89e-50 181.0 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales 28883|Caudovirales S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_384924_2 1096546.WYO_0201 2.29e-155 473.0 28P6A@1|root,2ZC10@2|Bacteria,1RBZE@1224|Proteobacteria,2UQEG@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_94762_2 279238.Saro_3021 1.68e-25 106.0 2AY7I@1|root,31Q9P@2|Bacteria,1MYBZ@1224|Proteobacteria,2UBAJ@28211|Alphaproteobacteria,2KAW8@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - k59_94762_3 717785.HYPMC_1852 1.85e-09 60.5 COG5055@1|root,COG5055@2|Bacteria,1QWK7@1224|Proteobacteria 1224|Proteobacteria L Protein of unknown function (DUF968) - - - - - - - - - - - - DUF968,ERF,Rad52_Rad22 k59_188188_1 1493510.A0A0E3ICC5_9CAUD 3.19e-41 155.0 4QB40@10239|Viruses,4QPWY@28883|Caudovirales,4QHVQ@10662|Myoviridae 10662|Myoviridae S nucleotide binding - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016032,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019058,GO:0019079,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0039686,GO:0039693,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044403,GO:0044419,GO:0046483,GO:0051704,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_337393_1 743299.Acife_0751 2.88e-21 94.7 COG1896@1|root,COG1896@2|Bacteria,1RACF@1224|Proteobacteria,1S2SY@1236|Gammaproteobacteria 1236|Gammaproteobacteria S 5'-deoxynucleotidase activity yfdR GO:0002953,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897 - ko:K06952 - - - - ko00000 - - - - k59_338206_1 246197.MXAN_1208 2.32e-75 245.0 COG0863@1|root,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_82806_2 145579.CAPSD_BPPHM 4.22e-84 276.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_9527_2 105154.Q9MBU0_9VIRU 2.57e-58 197.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_217394_1 8090.ENSORLP00000016650 6.89e-05 47.4 COG5479@1|root,2S2KY@2759|Eukaryota,3A1DX@33154|Opisthokonta,3BS3D@33208|Metazoa,3D8FQ@33213|Bilateria,48QFP@7711|Chordata,49M1R@7742|Vertebrata,4A42R@7898|Actinopterygii 33208|Metazoa T Peptidoglycan-recognition protein SC2-like PGLYRP1 GO:0000270,GO:0001775,GO:0001817,GO:0001818,GO:0001906,GO:0002218,GO:0002221,GO:0002225,GO:0002237,GO:0002252,GO:0002253,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002682,GO:0002683,GO:0002684,GO:0002694,GO:0002695,GO:0002697,GO:0002698,GO:0002699,GO:0002700,GO:0002702,GO:0002757,GO:0002758,GO:0002759,GO:0002760,GO:0002764,GO:0002784,GO:0002786,GO:0002803,GO:0002805,GO:0002807,GO:0002808,GO:0002816,GO:0002831,GO:0002833,GO:0002920,GO:0002922,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005539,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006810,GO:0006887,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006963,GO:0006965,GO:0007154,GO:0007165,GO:0007166,GO:0008063,GO:0008144,GO:0008150,GO:0008152,GO:0008329,GO:0008592,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009595,GO:0009605,GO:0009607,GO:0009617,GO:0009889,GO:0009891,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0012505,GO:0016019,GO:0016045,GO:0016192,GO:0016787,GO:0016810,GO:0016811,GO:0019222,GO:0019730,GO:0023051,GO:0023052,GO:0023056,GO:0030139,GO:0030141,GO:0030203,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031341,GO:0031343,GO:0031347,GO:0031348,GO:0031349,GO:0031410,GO:0031640,GO:0031974,GO:0031982,GO:0031983,GO:0032101,GO:0032102,GO:0032103,GO:0032494,GO:0032500,GO:0032649,GO:0032689,GO:0032814,GO:0032815,GO:0032823,GO:0032824,GO:0032826,GO:0032827,GO:0032940,GO:0033218,GO:0034248,GO:0034250,GO:0034774,GO:0035580,GO:0035821,GO:0036230,GO:0038023,GO:0038187,GO:0040007,GO:0042119,GO:0042221,GO:0042268,GO:0042277,GO:0042581,GO:0042742,GO:0042749,GO:0042752,GO:0042834,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0043299,GO:0043312,GO:0043900,GO:0043902,GO:0044110,GO:0044116,GO:0044117,GO:0044364,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045087,GO:0045088,GO:0045089,GO:0045187,GO:0045321,GO:0045335,GO:0045595,GO:0045596,GO:0045619,GO:0045620,GO:0045752,GO:0045824,GO:0045919,GO:0046903,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0050727,GO:0050728,GO:0050776,GO:0050777,GO:0050778,GO:0050789,GO:0050793,GO:0050794,GO:0050795,GO:0050830,GO:0050865,GO:0050866,GO:0050896,GO:0051093,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051239,GO:0051241,GO:0051249,GO:0051250,GO:0051606,GO:0051704,GO:0051707,GO:0051709,GO:0051710,GO:0051712,GO:0051714,GO:0051716,GO:0060089,GO:0060205,GO:0061783,GO:0061844,GO:0065007,GO:0070013,GO:0070820,GO:0071682,GO:0071704,GO:0080134,GO:0097013,GO:0097367,GO:0097708,GO:0098542,GO:0098543,GO:0098581,GO:0099503,GO:1900424,GO:1900426,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901700,GO:1902105,GO:1902106,GO:1903706,GO:1903707,GO:1904724,GO:2000026 - ko:K01446 - - R04112 RC00064,RC00141 ko00000 - - - Amidase_2 k59_361379_1 1234888.K0A2J2_9VIRU 2.16e-63 213.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_385782_1 940282.CADQ01000099_gene1065 9.12e-24 98.2 COG5655@1|root,COG5655@2|Bacteria 2|Bacteria L RePlication protein - - - - - - - - - - - - Rep_1 k59_326278_1 1188256.BASI01000007_gene2308 2.33e-24 99.0 COG0338@1|root,COG0338@2|Bacteria 2|Bacteria L D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_350099_2 1385658.U5KNR1_9VIRU 5.74e-26 107.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_217399_1 1247963.JPHU01000002_gene2748 5.36e-07 58.5 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria 28211|Alphaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_180526_2 1123257.AUFV01000013_gene2785 1.42e-23 102.0 COG0863@1|root,COG0863@2|Bacteria,1PCSE@1224|Proteobacteria,1SARI@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_58361_1 95619.PM1_0217750 6.64e-68 225.0 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,1RQFD@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage terminase, large subunit - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_58361_2 1094556.MCY_00456 2.52e-06 49.3 2ERGC@1|root,33J1W@2|Bacteria,1NN9S@1224|Proteobacteria,2UKDV@28211|Alphaproteobacteria,48U7V@772|Bartonellaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_167517_1 1234888.K0A2J2_9VIRU 4.37e-138 412.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_217400_1 697281.Mahau_0061 1.72e-05 53.9 COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia,42GRZ@68295|Thermoanaerobacterales 186801|Clostridia N tail tape measure protein TP901 core region - - - - - - - - - - - - PhageMin_Tail k59_34462_2 649639.Bcell_2721 1.59e-106 355.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,4HGW7@91061|Bacilli,1ZBWW@1386|Bacillus 91061|Bacilli D phage tail tape measure protein - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,SLT k59_144594_1 90371.CY43_01680 1.07e-19 88.2 COG4712@1|root,COG4712@2|Bacteria,1N9U1@1224|Proteobacteria 1224|Proteobacteria S Rad52/22 family double-strand break repair protein - - - - - - - - - - - - Rad52_Rad22 k59_181408_2 700598.Niako_2344 8.69e-15 73.6 COG1216@1|root,COG1216@2|Bacteria,4NPNF@976|Bacteroidetes 976|Bacteroidetes S Protein of unknown function (DUF616) - - - - - - - - - - - - DUF616 k59_253680_1 1238190.AMQY01000021_gene1593 4.43e-41 155.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,1S0Q1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L ORF located using Glimmer RBSfinder - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_59309_1 1349820.M707_02655 2.33e-18 78.6 2E5GW@1|root,3308F@2|Bacteria,2GX64@201174|Actinobacteria 201174|Actinobacteria S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_83905_2 1121438.JNJA01000039_gene1897 0.000144 48.5 2DNH7@1|root,32XH1@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_362350_1 77856.REP_BFDV 1.83e-17 84.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_168397_1 1288083.AUKR01000024_gene3453 4.38e-11 64.3 COG0863@1|root,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - 2.1.1.72 ko:K00571,ko:K07319 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_386708_1 359.CN09_09380 9.86e-32 124.0 COG0553@1|root,COG0553@2|Bacteria,1R7CK@1224|Proteobacteria,2U228@28211|Alphaproteobacteria,4BN0G@82115|Rhizobiaceae 28211|Alphaproteobacteria KL DNA methylase N-4 - - - - - - - - - - - - Helicase_C,N6_N4_Mtase k59_386708_2 1123288.SOV_2c10450 3.36e-65 207.0 COG0863@1|root,COG0863@2|Bacteria,1UZIN@1239|Firmicutes,4H3N6@909932|Negativicutes 909932|Negativicutes L DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_253689_1 1006004.GBAG_0472 1.02e-06 51.6 COG0827@1|root,COG0827@2|Bacteria,1MUZW@1224|Proteobacteria,1RSAY@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Domain of unknown function (DUF4942) - - - - - - - - - - - - DUF4942 k59_314671_1 1385658.U5KPZ6_9VIRU 1.01e-103 320.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_132814_3 1165094.RINTHH_3920 6.64e-75 238.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_132928_2 1218075.BAYA01000001_gene421 3.61e-31 121.0 28PTM@1|root,2ZCEU@2|Bacteria,1R5DD@1224|Proteobacteria,2W259@28216|Betaproteobacteria 28216|Betaproteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_71831_1 1030157.AFMP01000057_gene765 1.19e-12 67.4 2CC4A@1|root,2ZNID@2|Bacteria,1P8KR@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_277996_1 2003327.CAPSD_BPCHP 5.85e-61 209.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_218585_1 1028800.RG540_CH13740 3.92e-106 338.0 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,2TVEI@28211|Alphaproteobacteria,4BIH2@82115|Rhizobiaceae 28211|Alphaproteobacteria L DNA polymerase A domain - - - - - - - - - - - - DNA_pol_A k59_230332_1 634504.Bgr_07950 6.9e-31 135.0 COG3170@1|root,COG3170@2|Bacteria,1R69E@1224|Proteobacteria,2U3B9@28211|Alphaproteobacteria,48T9Q@772|Bartonellaceae 28211|Alphaproteobacteria NU Phage P22-like portal protein - - - - - - - - - - - - P22_portal k59_266061_1 1287116.X734_28730 0.000814 48.5 COG0152@1|root,COG0152@2|Bacteria 2|Bacteria F phosphoribosylaminoimidazolesuccinocarboxamide synthase activity purC - 4.1.1.21,6.3.2.6 ko:K01587,ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04209,R04591 RC00064,RC00162,RC00590 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt k59_315367_1 1236000.L0AQQ6_9CAUD 9.44e-135 416.0 4QB9Y@10239|Viruses,4QWGZ@35237|dsDNA viruses no RNA stage,4QPTT@28883|Caudovirales,4QJD7@10662|Myoviridae 10662|Myoviridae S hydrolase activity - - - - - - - - - - - - - k59_315367_3 1236000.L0AQZ2_9CAUD 1.3e-32 120.0 4QEGD@10239|Viruses,4QVU1@35237|dsDNA viruses no RNA stage,4QPN9@28883|Caudovirales,4QJCM@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_182069_1 13689.BV96_01268 7.32e-23 97.1 COG4422@1|root,COG4422@2|Bacteria,1MXQI@1224|Proteobacteria,2TVMB@28211|Alphaproteobacteria,2K6EE@204457|Sphingomonadales 204457|Sphingomonadales S Protein of unknown function (DUF5131) - - - - - - - - - - - - DUF5131 k59_36364_1 941449.dsx2_2649 1.11e-06 58.2 28IJ1@1|root,2Z8K0@2|Bacteria,1R5PC@1224|Proteobacteria,435JM@68525|delta/epsilon subdivisions,2WZXR@28221|Deltaproteobacteria,2M8CX@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_190119_1 105154.Q9MBU6_9VIRU 1.39e-129 386.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_72617_1 1385658.U5KQQ9_9VIRU 0.000854 47.4 4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_182073_1 1692244.A0A0K1RLR5_9CIRC 2.29e-37 142.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_182145_1 414684.RC1_3320 1.52e-69 238.0 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,2TT3N@28211|Alphaproteobacteria,2JQ8P@204441|Rhodospirillales 204441|Rhodospirillales S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_11254_4 871584.D9ZNG2_9CAUD 1.55e-07 53.5 4QAX8@10239|Viruses,4QVB1@35237|dsDNA viruses no RNA stage,4QPHH@28883|Caudovirales,4QKTJ@10699|Siphoviridae 10699|Siphoviridae S calcium ion binding - - - - - - - - - - - - - k59_388538_1 1618238.A0A0C5IB41_9CIRC 1.47e-24 108.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_192518_2 1692249.A0A0K1RLN8_9CIRC 7.6e-30 117.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_388564_2 1126411.I1TEL3_9CIRC 3.48e-38 143.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_192643_3 1415780.JPOG01000001_gene1744 2.83e-26 119.0 COG0454@1|root,COG0827@1|root,COG1040@1|root,COG3087@1|root,COG0456@2|Bacteria,COG0827@2|Bacteria,COG1040@2|Bacteria,COG3087@2|Bacteria,1PI1K@1224|Proteobacteria,1T6BU@1236|Gammaproteobacteria,1XB7I@135614|Xanthomonadales 135614|Xanthomonadales D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - - - - - - - - - - - k59_388574_1 1379692.S5SXY7_9CIRC 3.81e-17 85.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388574_3 1379692.S5SXY7_9CIRC 5.2e-19 88.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_193875_1 1210884.HG799467_gene13131 3.96e-23 102.0 COG0553@1|root,COG0553@2|Bacteria 2|Bacteria L helicase activity - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_193876_1 2003327.CAPSD_BPCHP 1.46e-09 65.1 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_304702_2 1460635.JCM19038_3780 4.07e-11 65.9 COG3409@1|root,COG3409@2|Bacteria 2|Bacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - Amidase_2,PG_binding_1 k59_85872_2 298653.Franean1_6564 2.88e-07 56.2 COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,4ERVT@85013|Frankiales 201174|Actinobacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 k59_353407_1 2003327.CAPSD_BPCHP 1.77e-07 53.9 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_280597_1 571.MC52_01410 2.3e-31 125.0 COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,1RPB0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S portal protein - - - - - - - - - - - - Phage_portal k59_280597_2 742821.HMPREF9464_01832 6.25e-35 130.0 COG3740@1|root,COG3740@2|Bacteria,1N2D8@1224|Proteobacteria,2VX9U@28216|Betaproteobacteria 28216|Betaproteobacteria S Caudovirus prohead serine protease - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78 k59_316782_3 742740.HMPREF9474_04296 2.86e-07 59.3 COG5280@1|root,COG5280@2|Bacteria,1UMXV@1239|Firmicutes 1239|Firmicutes S Phage tail tape measure protein TP901 - - - - - - - - - - - - - k59_85873_1 1380367.JIBC01000006_gene316 2.58e-53 176.0 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2UDUF@28211|Alphaproteobacteria 28211|Alphaproteobacteria G lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - PG_binding_1,Phage_lysozyme k59_134413_1 948071.S4S2L2_9CAUD 2.12e-05 52.0 4QHQ5@10239|Viruses,4QR7K@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_12816_1 1169152.AXVD01000007_gene2015 9.09e-05 46.2 COG0583@1|root,COG0583@2|Bacteria,2GMES@201174|Actinobacteria,4FUX2@85025|Nocardiaceae 201174|Actinobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - ko:K21703 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k59_219894_2 195253.Syn6312_0710 1.51e-15 84.7 COG1215@1|root,COG1215@2|Bacteria,1G12A@1117|Cyanobacteria,1H432@1129|Synechococcus 1117|Cyanobacteria M COG0463 Glycosyltransferases involved in cell wall biogenesis - - - - - - - - - - - - Glycos_transf_2 k59_992_1 1385658.U5KPZ6_9VIRU 1.08e-31 126.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_171022_1 335283.Neut_1460 2.78e-15 77.4 COG1196@1|root,COG1345@1|root,COG1196@2|Bacteria,COG1345@2|Bacteria,1PDRQ@1224|Proteobacteria,2W14R@28216|Betaproteobacteria 28216|Betaproteobacteria D Prophage tail length tape measure protein - - - - - - - - - - - - TMP_2 k59_341083_3 352165.HMPREF7215_2591 4.55e-39 148.0 COG5410@1|root,COG5410@2|Bacteria 2|Bacteria K chromosome segregation - - - - - - - - - - - - Terminase_6,Terminase_6C k59_98157_1 1379717.S5SY19_9CIRC 1.73e-26 108.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_316919_1 596151.DesfrDRAFT_0046 4.33e-08 55.1 2AIEP@1|root,318W6@2|Bacteria,1Q124@1224|Proteobacteria,43721@68525|delta/epsilon subdivisions,2X1T5@28221|Deltaproteobacteria,2MFMI@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_134447_7 709797.CSIRO_3068 1.13e-11 73.6 2CK1H@1|root,33WMM@2|Bacteria,1RF5H@1224|Proteobacteria,2UMV7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_244229_1 561175.KB894106_gene4450 3.9e-07 57.4 COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,2GNNQ@201174|Actinobacteria 201174|Actinobacteria KT Phage tail tape measure protein TP901 - - - - - - - - - - - - NLPC_P60,SLT k59_62447_6 1500259.JQLD01000001_gene4258 1.07e-05 52.4 COG3108@1|root,COG3108@2|Bacteria,1RIAK@1224|Proteobacteria,2UAXX@28211|Alphaproteobacteria,4B86A@82115|Rhizobiaceae 28211|Alphaproteobacteria S Bacterial protein of unknown function (DUF882) - - - - - - - - - - - - Peptidase_M15_3 k59_305342_1 1429767.W6ARH7_9CAUD 2.45e-53 185.0 4QAR1@10239|Viruses,4QUNA@35237|dsDNA viruses no RNA stage,4QPJE@28883|Caudovirales,4QNDS@10744|Podoviridae 10744|Podoviridae S ATPase activity - - - - - - - - - - - - - k59_159635_1 1609634.A0A0C5AFV4_9VIRU 2.36e-25 105.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_171647_1 768710.DesyoDRAFT_5195 2.5e-09 63.5 2DT4K@1|root,33INK@2|Bacteria,1VQEE@1239|Firmicutes,253M4@186801|Clostridia 1239|Firmicutes - - - - - - - - - - - - - - - k59_317668_1 1379725.S5TMY9_9CIRC 1.29e-13 75.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_256707_2 1234888.K0A2J2_9VIRU 4.34e-109 339.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_281557_2 1283076.M1I7V7_9CAUD 1.07e-87 289.0 4QAKZ@10239|Viruses,4QUSW@35237|dsDNA viruses no RNA stage,4QPYH@28883|Caudovirales,4QIYN@10662|Myoviridae 10662|Myoviridae S exonuclease activity - - - - - - - - - - - - - k59_268854_3 1219035.NT2_13_00580 1.33e-43 160.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_110932_1 13333.ERN14768 3.78e-99 317.0 28HK1@1|root,2QPXS@2759|Eukaryota,37NXW@33090|Viridiplantae,3GF00@35493|Streptophyta 35493|Streptophyta L Twinkle homolog protein chloroplastic - GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0004003,GO:0004386,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016043,GO:0016070,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032392,GO:0032508,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051276,GO:0055086,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090407,GO:0097159,GO:0097747,GO:0140097,GO:0140098,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_4 k59_123200_5 1485544.JQKP01000011_gene745 3.64e-18 82.8 2E645@1|root,330T3@2|Bacteria,1NEGX@1224|Proteobacteria,2VY99@28216|Betaproteobacteria 28216|Betaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_123200_7 521000.PROVRETT_05530 3.64e-26 100.0 COG3179@1|root,COG3179@2|Bacteria,1RE8K@1224|Proteobacteria,1S4U8@1236|Gammaproteobacteria,3Z9BP@586|Providencia 1236|Gammaproteobacteria S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Peptidase_M15_4 k59_123200_9 1197951.I6RT34_9CAUD 8.57e-46 164.0 4QGAG@10239|Viruses,4R0KB@35237|dsDNA viruses no RNA stage,4QUA4@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_1584_7 742733.HMPREF9469_05076 9.39e-22 95.9 2B7V5@1|root,3211Y@2|Bacteria,1V7MK@1239|Firmicutes,24JA7@186801|Clostridia,222WR@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_1584_8 478749.BRYFOR_08565 2.44e-50 174.0 2A0KC@1|root,2ZGJK@2|Bacteria,1V2JS@1239|Firmicutes,24H6R@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_366446_5 1609634.A0A0C5AFV4_9VIRU 4.69e-48 179.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_330477_2 1475143.W8SNN0_9CIRC 1.62e-39 151.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_318410_8 1207063.P24_17292 1.55e-06 51.2 2DRG1@1|root,33BJN@2|Bacteria,1NKMQ@1224|Proteobacteria 1224|Proteobacteria S HIRAN domain - - - - - - - - - - - - HIRAN k59_378792_4 1200792.AKYF01000009_gene2949 1.76e-92 284.0 COG0451@1|root,COG0451@2|Bacteria,1TQV2@1239|Firmicutes,4HBXU@91061|Bacilli,26R1Z@186822|Paenibacillaceae 91061|Bacilli GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction fcl - 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R05692 RC01014 ko00000,ko00001,ko01000 - - - Epimerase k59_147841_2 240016.ABIZ01000001_gene5053 4.86e-45 164.0 2DR7Z@1|root,33AM6@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_257338_3 1168281.I3PUX1_9CAUD 8.51e-22 106.0 4QBFN@10239|Viruses,4QXWN@35237|dsDNA viruses no RNA stage,4QPTW@28883|Caudovirales,4QNPZ@10744|Podoviridae 10744|Podoviridae S Phage stabilisation protein - - - - - - - - - - - - - k59_257338_9 1121438.JNJA01000039_gene1897 0.000716 51.6 2DNH7@1|root,32XH1@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_330481_1 1403946.Q615_SPAC00114G0060 7.7e-18 87.0 COG0270@1|root,COG0270@2|Bacteria,1TQS8@1239|Firmicutes,4HE50@91061|Bacilli 91061|Bacilli L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_282550_1 1618251.A0A0C5I2L8_9CIRC 2.83e-39 147.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_209240_1 1504822.CCNO01000008_gene2039 2.95e-20 95.1 COG0305@1|root,COG0305@2|Bacteria,2NNKG@2323|unclassified Bacteria 2|Bacteria L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_330619_1 1498011.A0A096XUV0_9CAUD 1.29e-22 94.7 4QAIU@10239|Viruses,4QPDE@28883|Caudovirales,4QNBQ@10744|Podoviridae 10744|Podoviridae S HNH endonuclease - - - - - - - - - - - - - k59_354752_1 1986029.Q9MBM3_9VIRU 9.78e-39 142.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_2308_1 420324.KI911970_gene1463 4.78e-82 261.0 COG5410@1|root,COG5410@2|Bacteria,1N0W2@1224|Proteobacteria,2U18J@28211|Alphaproteobacteria 28211|Alphaproteobacteria K chromosome segregation - - - - - - - - - - - - Terminase_6C k59_50933_1 691965.D4P7I3_9CAUD 3.05e-166 504.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_38537_5 1239962.C943_04149 2.34e-09 58.2 COG1403@1|root,COG1403@2|Bacteria,4NT0M@976|Bacteroidetes,47WM2@768503|Cytophagia 976|Bacteroidetes V HNH nucleases - - - - - - - - - - - - - k59_147946_1 1279009.ADICEAN_01726 1.57e-36 140.0 COG0562@1|root,COG0562@2|Bacteria,4NGXU@976|Bacteroidetes,47KQW@768503|Cytophagia 976|Bacteroidetes M UDP-galactopyranose mutase - - 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 - R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 - - - GLF,NAD_binding_8 k59_257424_2 1234888.K0A2J2_9VIRU 6.56e-17 82.8 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_14132_3 1611039.A0A0C5C3Z3_9CIRC 9.57e-25 103.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_209826_1 1618248.A0A0C5IB82_9CIRC 1.17e-74 237.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_63852_1 1150621.SMUL_1068 4.88e-15 73.6 COG3108@1|root,COG3108@2|Bacteria,1NCZX@1224|Proteobacteria,42VTQ@68525|delta/epsilon subdivisions,2YQTW@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k59_63852_2 1609634.A0A0C5AFT2_9VIRU 3.14e-20 92.8 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_257936_1 1618248.A0A0C5IB82_9CIRC 2.51e-15 79.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_342882_1 1385658.U5KPZ6_9VIRU 5.59e-192 554.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_233709_1 1157490.EL26_22985 8.25e-05 53.5 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1TSMG@1239|Firmicutes,4HBFH@91061|Bacilli,279IG@186823|Alicyclobacillaceae 91061|Bacilli S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_75671_2 1609634.A0A0C5AFV4_9VIRU 4.8e-196 565.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_3007_2 1618249.A0A0C5IBT4_9CIRC 5.97e-20 97.1 4QB6C@10239|Viruses,4QUKM@29258|ssDNA viruses 10239|Viruses J Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_294440_1 1121441.AUCX01000032_gene3179 2.51e-87 330.0 COG0503@1|root,COG0827@1|root,COG0503@2|Bacteria,COG0827@2|Bacteria,1QZ6D@1224|Proteobacteria,42Z8W@68525|delta/epsilon subdivisions,2WU49@28221|Deltaproteobacteria,2MAY9@213115|Desulfovibrionales 28221|Deltaproteobacteria LMNU Methyltransferase small domain - - - - - - - - - - - - MTS k59_209856_1 948071.S4S2T1_9CAUD 5.97e-175 515.0 4QHPY@10239|Viruses,4QWIA@35237|dsDNA viruses no RNA stage,4QSXS@28883|Caudovirales,4QNJ2@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_319130_3 467481.B0VK09_9CAUD 4.11e-16 78.2 4QB0W@10239|Viruses,4QZQH@35237|dsDNA viruses no RNA stage,4QQW9@28883|Caudovirales,4QN19@10699|Siphoviridae 10699|Siphoviridae S Protein of unknown function (DUF1064) - - - - - - - - - - - - - k59_160938_1 1692242.A0A0K1RL37_9CIRC 3.67e-18 89.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_245615_1 86416.Clopa_4295 2.32e-27 111.0 2CWXD@1|root,32T0J@2|Bacteria,1VJPE@1239|Firmicutes,25DQE@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_331277_5 1123518.ARWI01000001_gene2291 3.14e-44 160.0 COG4397@1|root,COG4397@2|Bacteria,1MWX8@1224|Proteobacteria,1RR4A@1236|Gammaproteobacteria,462A0@72273|Thiotrichales 72273|Thiotrichales S Mu-like prophage major head subunit gpT - - - - - - - - - - - - Mu-like_gpT k59_331277_7 1122128.AUEE01000009_gene1424 5.22e-25 113.0 COG0616@1|root,COG0616@2|Bacteria,1TRQW@1239|Firmicutes,4HB4R@91061|Bacilli,4GYBM@90964|Staphylococcaceae 91061|Bacilli OU Peptidase family S49 sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 k59_3020_1 1618247.A0A0C5IMK7_9CIRC 2.11e-06 52.4 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_342936_2 1179778.PMM47T1_10725 2.79e-22 92.8 COG3108@1|root,COG3108@2|Bacteria,1N1HE@1224|Proteobacteria,1SCII@1236|Gammaproteobacteria 1236|Gammaproteobacteria S peptidase M15A - - - - - - - - - - - - Peptidase_M15_3 k59_379491_5 156889.Mmc1_1716 1.47e-14 81.6 28NGF@1|root,2ZBII@2|Bacteria,1R9KY@1224|Proteobacteria,2U1P7@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_380148_1 1234888.K0A2J2_9VIRU 3.7e-99 306.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_125349_1 105154.Q9MBU6_9VIRU 1.61e-104 322.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_173687_1 1609634.A0A0C5AFV4_9VIRU 5.44e-31 120.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_173687_3 1609634.A0A0C5AFT2_9VIRU 1.56e-64 212.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_380149_1 105154.Q9MBU6_9VIRU 5.3e-95 298.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_88659_1 1692242.A0A0K1RL37_9CIRC 2.59e-53 177.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_125352_1 1618247.A0A0C5I2K0_9CIRC 1.02e-08 59.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_76319_3 926560.KE387023_gene2268 0.000191 45.1 COG4712@1|root,COG4712@2|Bacteria,1WIU2@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Rad52 22 double-strand break repair protein ddrA GO:0001101,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009269,GO:0009314,GO:0009414,GO:0009415,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010212,GO:0010332,GO:0031668,GO:0033554,GO:0034641,GO:0042221,GO:0042631,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070887,GO:0071214,GO:0071229,GO:0071462,GO:0071465,GO:0071478,GO:0071479,GO:0071480,GO:0071496,GO:0071704,GO:0090304,GO:0104004,GO:1901360,GO:1901700,GO:1901701 - - - - - - - - - - Rad52_Rad22 k59_246356_4 106370.Francci3_2345 0.000203 47.8 COG0863@1|root,COG0863@2|Bacteria,2I9DJ@201174|Actinobacteria 201174|Actinobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.113,2.1.1.72 ko:K00571,ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_210514_1 1540097.A0A0A0YU43_9CAUD 3.91e-40 148.0 4QBMV@10239|Viruses,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_100882_1 749414.SBI_08575 2.4e-34 131.0 COG0438@1|root,COG0438@2|Bacteria,2HH27@201174|Actinobacteria 201174|Actinobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 k59_136987_3 1986029.Q9MBM8_9VIRU 3.51e-53 182.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_235015_2 742740.HMPREF9474_02267 3.18e-28 108.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia,221N8@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_15498_2 411460.RUMTOR_01339 3.21e-46 157.0 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_4483_4 1207055.C100_20610 3.78e-05 46.2 COG1396@1|root,COG1396@2|Bacteria,1N6TH@1224|Proteobacteria,2U85N@28211|Alphaproteobacteria,2KAXF@204457|Sphingomonadales 204457|Sphingomonadales K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - - k59_89447_3 470.IX87_10415 4.19e-05 47.4 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,1SA7C@1236|Gammaproteobacteria,3NSKU@468|Moraxellaceae 1236|Gammaproteobacteria G Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - PG_binding_1,Phage_lysozyme k59_332571_1 1692244.A0A0K1RLR5_9CIRC 1.7e-37 137.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_113460_3 455436.DS989811_gene1797 0.000626 45.8 2E645@1|root,330T3@2|Bacteria,1NEGX@1224|Proteobacteria,1SC3K@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_77116_1 1165094.RINTHH_3920 6.1e-16 80.1 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_247160_1 1150626.PHAMO_290112 9.02e-39 149.0 28HCK@1|root,2Z7PE@2|Bacteria,1NK7S@1224|Proteobacteria,2TSMJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_356628_1 932678.THERU_00605 1.35e-52 189.0 COG0587@1|root,COG0587@2|Bacteria,2G3PZ@200783|Aquificae 200783|Aquificae L TIGRFAM DNA polymerase III, alpha subunit dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,Intein_splicing,LAGLIDADG_3,PHP,tRNA_anti-codon k59_368458_1 1051675.G0YQH7_9CAUD 1.4e-42 150.0 4QGGR@10239|Viruses,4QZHR@35237|dsDNA viruses no RNA stage,4QUGZ@28883|Caudovirales,4QNY3@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_65316_2 447909.A6M999_9VIRU 1.55e-24 96.7 4QDCG@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_295962_1 1552758.NC00_01265 1.24e-80 266.0 COG3567@1|root,COG3567@2|Bacteria,1QNPU@1224|Proteobacteria,1S4PU@1236|Gammaproteobacteria,1X7HW@135614|Xanthomonadales 135614|Xanthomonadales S to SP P44183 (percent identity 30 query alignment coverage 92.9 subject alignment coverage 99.5 - - - ko:K09961 - - - - ko00000 - - - DUF1073 k59_89528_1 716544.wcw_0671 2.5e-45 169.0 COG4626@1|root,COG4626@2|Bacteria 2|Bacteria S Terminase - - - - - - - - - - - - Terminase_1 k59_102288_1 2003327.CAPSD_BPCHP 4.63e-33 130.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_90264_1 568703.LGG_02296 8.46e-94 308.0 COG0209@1|root,COG0209@2|Bacteria,1TT3U@1239|Firmicutes,4HFF1@91061|Bacilli,3F3VU@33958|Lactobacillaceae 91061|Bacilli F ribonucleoside-triphosphate reductase activity rtpR - 1.17.4.2 ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02014,R02020,R02022,R02023,R04315 RC00013,RC00613 ko00000,ko00001,ko00002,ko01000 - - - Ribonuc_red_lgC k59_285880_1 105154.Q9MBU0_9VIRU 1.41e-12 70.9 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_5163_2 1249627.D779_3597 3.38e-25 103.0 COG0417@1|root,COG0417@2|Bacteria 2|Bacteria L DNA replication proofreading polB - 2.7.7.7 ko:K02336,ko:K06877,ko:K07501 - - - - ko00000,ko01000,ko03400 - - - DNA_pol_B,DNA_pol_B_exo1,DNA_pol_B_exo2,RNase_H_2 k59_247963_5 1609634.A0A0C5AFT2_9VIRU 3.73e-137 399.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_247963_6 105154.Q9MBT9_9VIRU 3.99e-12 64.3 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_247963_7 1609634.A0A0C5AFV4_9VIRU 3.26e-256 717.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_247963_8 1609634.A0A0C5ANA6_9VIRU 4.26e-19 87.8 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_41309_1 216596.RL3938 7.97e-14 72.0 COG4626@1|root,COG4626@2|Bacteria,1R2FH@1224|Proteobacteria,2UCW2@28211|Alphaproteobacteria,4BCYA@82115|Rhizobiaceae 28211|Alphaproteobacteria S Terminase - - - - - - - - - - - - - k59_381714_2 1000565.METUNv1_01724 5.16e-17 87.4 COG3723@1|root,COG3723@2|Bacteria,1R6DB@1224|Proteobacteria,2VNV4@28216|Betaproteobacteria 28216|Betaproteobacteria L RecT family recT - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_381714_3 1325130.HFN_0354 5.08e-15 75.1 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42RN6@68525|delta/epsilon subdivisions,2YP9W@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_212241_1 29486.NJ56_14910 1.07e-14 80.5 28HY4@1|root,2Z83J@2|Bacteria,1Q1KZ@1224|Proteobacteria,1SVB7@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_369240_1 467661.RKLH11_1236 2.07e-47 170.0 COG0863@1|root,COG0863@2|Bacteria,1MY4G@1224|Proteobacteria,2U1X0@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_212243_1 1267535.KB906767_gene5409 0.000479 48.5 2C4I1@1|root,33QND@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_235739_1 1384484.AEQU_1746 8.67e-26 108.0 COG1180@1|root,COG1180@2|Bacteria,2HSWV@201174|Actinobacteria,4CVGK@84998|Coriobacteriia 84998|Coriobacteriia C Elongator protein 3, MiaB family, Radical SAM - - 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Radical_SAM k59_224186_6 1385658.U5KNR1_9VIRU 2.36e-45 164.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_224186_8 1609634.A0A0C5AFV4_9VIRU 8.69e-54 189.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_345338_1 1219035.NT2_13_00580 7.18e-08 54.3 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_212244_2 324602.Caur_1741 8.59e-09 66.2 COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria 2|Bacteria V Glycosyl transferase, family 2 - - - ko:K07011 - - - - ko00000 - - - Glyco_tranf_2_3,Glycos_transf_1,Glycos_transf_2 k59_16287_2 1172185.KB911511_gene2923 4.35e-08 58.5 COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4FVBU@85025|Nocardiaceae 201174|Actinobacteria IQ AMP-binding enzyme C-terminal domain fadD3 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087 6.2.1.41 ko:K18687 ko00984,ko01100,ko01120,map00984,map01100,map01120 - R10769 RC00004,RC00014 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C k59_224953_1 1122137.AQXF01000002_gene217 2e-09 63.2 COG3064@1|root,COG3064@2|Bacteria,1NQ5T@1224|Proteobacteria,2UK7G@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Membrane - - - - - - - - - - - - PTR k59_382278_1 1476391.X5KNB4_9CAUD 1.02e-36 147.0 4QAXA@10239|Viruses,4QYJI@35237|dsDNA viruses no RNA stage,4QQ1A@28883|Caudovirales,4QNU7@10744|Podoviridae 10744|Podoviridae S metallopeptidase activity - - - - - - - - - - - - - k59_236401_2 658187.LDG_6143 1.65e-24 115.0 COG0467@1|root,COG1119@1|root,COG0467@2|Bacteria,COG1119@2|Bacteria 2|Bacteria P ATPase activity - - - ko:K03546,ko:K06919,ko:K07452,ko:K08482,ko:K09384,ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko01000,ko02042,ko02048,ko03400 - - - AAA_11,AAA_12,AAA_25,DUF4011 k59_382280_1 105154.Q9MBU6_9VIRU 1.33e-98 305.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_382280_2 1609634.A0A0C5ANA6_9VIRU 1.32e-11 66.6 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_346058_1 1196322.A370_02072 4.95e-72 231.0 COG3723@1|root,COG3723@2|Bacteria,1UNDF@1239|Firmicutes,24ECD@186801|Clostridia,36HN4@31979|Clostridiaceae 186801|Clostridia L RecT family - - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_163922_1 1403819.BATR01000079_gene2262 2.94e-211 604.0 COG4626@1|root,COG4626@2|Bacteria,46ZJ1@74201|Verrucomicrobia,2IV51@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Terminase - - - - - - - - - - - - - k59_42250_1 1123508.JH636442_gene4470 2.03e-23 99.4 COG3087@1|root,COG3087@2|Bacteria,2IX3F@203682|Planctomycetes 203682|Planctomycetes D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - - - - - - - - - - - k59_164840_2 428125.CLOLEP_01398 3.17e-34 120.0 2CGGB@1|root,32UNH@2|Bacteria,1VD9W@1239|Firmicutes,24MWC@186801|Clostridia,3WPKG@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_164840_3 742740.HMPREF9474_02279 6.44e-66 207.0 29YRZ@1|root,30KMY@2|Bacteria,1V4Y4@1239|Firmicutes,24HPY@186801|Clostridia,221XY@1506553|Lachnoclostridium 186801|Clostridia S Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_164840_4 742733.HMPREF9469_05039 1.46e-21 98.2 28JED@1|root,2Z98K@2|Bacteria,1TW1U@1239|Firmicutes,24CFD@186801|Clostridia,2226E@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - GerE k59_177243_1 1475143.W8SNN0_9CIRC 8.77e-13 75.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_67785_1 1609634.A0A0C5AFV4_9VIRU 3.61e-20 90.1 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_201147_2 1234888.K0A2R8_9VIRU 2.86e-19 93.6 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_287989_1 1094496.m07a_12040 1.97e-09 64.3 COG3170@1|root,COG3170@2|Bacteria,1R69E@1224|Proteobacteria,2U3B9@28211|Alphaproteobacteria,48TPA@772|Bartonellaceae 28211|Alphaproteobacteria NU Phage P22-like portal protein - - - - - - - - - - - - P22_portal k59_140505_2 1618248.A0A0C5IB82_9CIRC 3.47e-19 90.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_358860_2 105154.Q9MBU6_9VIRU 3.78e-18 84.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_358860_3 105154.Q9MBU6_9VIRU 5.05e-27 109.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_55343_1 1391647.AVSV01000039_gene1108 2.32e-09 65.5 COG1340@1|root,COG5283@1|root,COG1340@2|Bacteria,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,25E9Q@186801|Clostridia,36USH@31979|Clostridiaceae 186801|Clostridia D phage tail tape measure protein - - - - - - - - - - - - PhageMin_Tail k59_237352_2 748247.AZKH_3967 9.21e-32 117.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2VR2Z@28216|Betaproteobacteria,2KWHT@206389|Rhodocyclales 206389|Rhodocyclales L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_274149_3 1321778.HMPREF1982_03147 1.04e-09 63.2 COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,24FZX@186801|Clostridia,269AP@186813|unclassified Clostridiales 186801|Clostridia T Psort location Cytoplasmic, score degU - - - - - - - - - - - GerE,Response_reg k59_55397_2 1524467.IV04_20380 1.3e-96 296.0 COG0863@1|root,COG0863@2|Bacteria,1MY4G@1224|Proteobacteria,1RQHA@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.113,2.1.1.72 ko:K00571,ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_335176_1 1227352.C173_13411 3.47e-14 80.9 COG0366@1|root,COG2819@1|root,COG4733@1|root,COG0366@2|Bacteria,COG2819@2|Bacteria,COG4733@2|Bacteria,1TXXX@1239|Firmicutes,4I70R@91061|Bacilli,26VRX@186822|Paenibacillaceae 91061|Bacilli G Starch binding domain - - - - - - - - - - - - CBM_25 k59_214207_3 1218352.B597_019440 1.87e-13 69.3 COG4570@1|root,COG4570@2|Bacteria,1N92D@1224|Proteobacteria,1TA3B@1236|Gammaproteobacteria,1Z47G@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria L Endodeoxyribonuclease RusA - - - - - - - - - - - - RusA k59_310813_2 1229204.AMYY01000059_gene2679 6.71e-08 52.8 2EK5N@1|root,33DW2@2|Bacteria,1NHDG@1224|Proteobacteria,2UJBG@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_186734_2 313628.LNTAR_02789 1.72e-07 54.3 COG0758@1|root,COG0758@2|Bacteria 2|Bacteria LU DNA mediated transformation smf - - ko:K04096 - - - - ko00000 - - - DNA_processg_A,DUF2493,MoCo_carrier k59_186734_3 1391647.AVSV01000017_gene675 4.27e-09 59.7 COG1525@1|root,COG1525@2|Bacteria,1VASF@1239|Firmicutes,24G14@186801|Clostridia,36I19@31979|Clostridiaceae 186801|Clostridia L Staphylococcal nuclease homologues - - 3.1.31.1 ko:K01174 - - - - ko00000,ko01000 - - - Ada_Zn_binding,Cu_amine_oxidN1,SNase k59_166054_2 1211777.BN77_4169 1.3e-84 263.0 2C5GI@1|root,2Z8C1@2|Bacteria,1R8XM@1224|Proteobacteria,2TUME@28211|Alphaproteobacteria,4BJKS@82115|Rhizobiaceae 28211|Alphaproteobacteria S P22 coat protein - gene protein 5 - - - - - - - - - - - - P22_CoatProtein k59_251080_2 105154.Q9MBU6_9VIRU 5.91e-71 231.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_202601_1 1509405.GV67_03955 8.22e-25 105.0 COG0338@1|root,COG0338@2|Bacteria,1P85S@1224|Proteobacteria,2TS2X@28211|Alphaproteobacteria,4BAP3@82115|Rhizobiaceae 28211|Alphaproteobacteria L D12 class N6 adenine-specific DNA methyltransferase dam2 - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_336608_1 1234888.K0A2J2_9VIRU 5.07e-48 169.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_289494_1 1452718.JBOY01000124_gene1280 1.87e-17 95.1 COG4227@1|root,COG4227@2|Bacteria 2|Bacteria L nucleotidyltransferase activity - - - ko:K18837 - - - - ko00000,ko02048 - - - CbtA_toxin,DUF1738,DUF3849,Helicase_C,N6_Mtase,SNF2_N k59_8140_1 82995.CR62_16710 1e-06 56.6 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,1RR0M@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_372305_7 1003200.AXXA_03459 3.82e-54 184.0 COG3409@1|root,COG3409@2|Bacteria,1RAYU@1224|Proteobacteria,2VPG4@28216|Betaproteobacteria 28216|Betaproteobacteria M N-acetylmuramidase - - - - - - - - - - - - Muraidase,PG_binding_1 k59_227438_1 1385658.U5KPZ6_9VIRU 1.81e-61 213.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_105303_2 1609634.A0A0C5ANA6_9VIRU 1.4e-07 57.4 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_251092_2 1300350.DSW25_02400 6.89e-37 137.0 COG3935@1|root,COG3935@2|Bacteria,1MXB6@1224|Proteobacteria,2U3BK@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DnaD domain protein - - - - - - - - - - - - - k59_251219_6 1385658.U5KPZ6_9VIRU 3.97e-251 704.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_215763_3 1475143.W8SNN0_9CIRC 7.98e-35 138.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_227586_1 1287116.X734_30975 5.17e-07 56.6 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,2TVGJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_8299_1 1556290.A0A0A0RQH0_9CAUD 6.46e-12 72.0 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_263957_2 198110.B3FK10_9CAUD 1.15e-26 108.0 4QBHW@10239|Viruses,4QVHG@35237|dsDNA viruses no RNA stage,4QTT7@28883|Caudovirales,4QJZQ@10662|Myoviridae 10662|Myoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_20151_1 1120792.JAFV01000001_gene3400 8e-33 131.0 COG4951@1|root,COG4951@2|Bacteria 2|Bacteria - - XK27_08510 - - ko:K06919 - - - - ko00000 - - - DUF1882,Helicase_C,ResIII k59_106300_3 1459636.NTE_01560 3.6e-13 70.5 COG1573@1|root,arCOG00905@2157|Archaea,41SJ1@651137|Thaumarchaeota 651137|Thaumarchaeota L uracil-DNA glycosylase - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_337786_4 1123368.AUIS01000020_gene1078 2.58e-17 83.2 28XPA@1|root,2ZJK5@2|Bacteria,1P9T2@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_337786_7 1562701.BBOF01000016_gene480 2.68e-26 112.0 COG5377@1|root,COG5377@2|Bacteria,1MWP8@1224|Proteobacteria,2VJH5@28216|Betaproteobacteria,1K2RX@119060|Burkholderiaceae 28216|Betaproteobacteria L YqaJ-like viral recombinase domain - - - - - - - - - - - - YqaJ k59_106306_1 1540097.A0A0A0YW88_9CAUD 4.89e-65 219.0 4QGA5@10239|Viruses,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_9098_1 2003327.CAPSD_BPCHP 1.08e-137 417.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_9098_2 1609634.A0A0C5ANA6_9VIRU 1.37e-05 53.1 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_70349_1 1279017.AQYJ01000016_gene407 7.88e-20 94.0 COG4733@1|root,COG4733@2|Bacteria,1R77Q@1224|Proteobacteria 1224|Proteobacteria D nuclear chromosome segregation - - - - - - - - - - - - - k59_131300_4 935948.KE386495_gene2256 1.1e-18 82.8 COG3405@1|root,COG3405@2|Bacteria,1VBUA@1239|Firmicutes 1239|Firmicutes G Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - - - - - - - - - - - k59_385371_1 1288963.ADIS_2346 1.31e-19 87.8 COG0207@1|root,COG0207@2|Bacteria,4NEC2@976|Bacteroidetes,47KE8@768503|Cytophagia 976|Bacteroidetes F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k59_188553_1 1127518.H9C119_9CAUD 9.83e-08 55.5 4QHD5@10239|Viruses,4QWUC@35237|dsDNA viruses no RNA stage,4QQGJ@28883|Caudovirales,4QJT5@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_216915_1 1121382.JQKG01000001_gene2497 1.47e-11 69.3 COG0210@1|root,COG0210@2|Bacteria,1WN9U@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L UvrD-like helicase C-terminal domain - - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k59_106408_1 244582.JQAK01000008_gene619 1.03e-45 174.0 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,2TQWC@28211|Alphaproteobacteria,47EZE@766|Rickettsiales 766|Rickettsiales L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k59_9165_1 1121937.AUHJ01000009_gene1510 1.2e-58 202.0 COG0823@1|root,COG0823@2|Bacteria,1R4CN@1224|Proteobacteria,1S0NH@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - PD40 k59_155558_1 2003327.CAPSD_BPCHP 1.35e-46 169.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_20233_1 926564.KI911577_gene452 5.49e-69 227.0 COG0749@1|root,COG0749@2|Bacteria,2I975@201174|Actinobacteria 201174|Actinobacteria L COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_pol_A,DNA_pol_A_exo1 k59_203827_2 1003195.SCAT_1653 2.86e-20 85.1 2EI4V@1|root,33BW7@2|Bacteria,2I5MI@201174|Actinobacteria 201174|Actinobacteria S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_203827_3 1556290.A0A0A0RM00_9CAUD 2.35e-80 259.0 4QAXQ@10239|Viruses,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_180104_1 1385658.U5KPZ6_9VIRU 2.04e-56 193.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_361037_1 663278.Ethha_2633 3.87e-32 132.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,3WGRT@541000|Ruminococcaceae 186801|Clostridia L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_277464_1 1618254.A0A0C5IBG4_9CIRC 3.07e-91 273.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_83595_1 1379698.RBG1_1C00001G0396 6.51e-14 76.3 COG0707@1|root,COG0707@2|Bacteria,2NP4Z@2323|unclassified Bacteria 2|Bacteria M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227,6.3.2.8 ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 - R03193,R05032,R05662 RC00005,RC00049,RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - GT28 iLJ478.TM0232,iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089 Glyco_tran_28_C,Glyco_transf_28 k59_144301_1 1385658.U5KNR1_9VIRU 5.6e-66 217.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_144301_3 105154.Q9MBU6_9VIRU 2.68e-156 459.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_277631_1 1618247.A0A0C5IMK7_9CIRC 0.00013 48.9 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_218169_2 1219035.NT2_13_00580 1.32e-61 211.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_107641_2 240302.BN982_04115 3.56e-10 61.6 COG5437@1|root,COG5437@2|Bacteria,1VFXV@1239|Firmicutes,4HNWZ@91061|Bacilli 91061|Bacilli S Phage tail tube protein - - - - - - - - - - - - Phage_tail_2 k59_107641_3 398512.JQKC01000005_gene5459 4.5e-05 45.8 2A9VX@1|root,30Z3W@2|Bacteria,1UC69@1239|Firmicutes,24VEV@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_83606_4 1357732.A0A059PYD9_9CAUD 5.31e-07 53.9 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_339048_1 1692256.A0A0K1RL85_9CIRC 2.12e-10 66.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_314402_1 1003195.SCAT_1684 3.94e-08 60.1 COG0576@1|root,COG4487@1|root,COG0576@2|Bacteria,COG4487@2|Bacteria 2|Bacteria I mechanosensitive ion channel activity dnaG - 3.4.21.102 ko:K02316,ko:K03561,ko:K03687,ko:K03797 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko01002,ko02000,ko03029,ko03032,ko03110 1.A.30.2.1 - - GrpE,HTH_26,TPM_phosphatase k59_302833_1 543632.JOJL01000003_gene8599 3.69e-26 99.8 2CC1Y@1|root,32RUK@2|Bacteria,2IQ4Q@201174|Actinobacteria,4DFEX@85008|Micromonosporales 201174|Actinobacteria K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA whiB2 - - ko:K18955 - - - - ko00000,ko03000 - - - Whib k59_35240_1 1282360.ABAC460_19840 2.4e-74 241.0 COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria 1224|Proteobacteria C SMART Elongator protein 3 MiaB NifB - - - - - - - - - - - - B12-binding,Radical_SAM k59_327067_1 1219035.NT2_13_00580 5.08e-31 124.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_168137_1 1469613.JT55_09240 2.18e-06 51.6 COG1100@1|root,COG1100@2|Bacteria,1N5QS@1224|Proteobacteria,2TSKW@28211|Alphaproteobacteria 28211|Alphaproteobacteria S AAA domain - - - - - - - - - - - - AAA_24 k59_168137_2 1538804.A0A088FAP5_9CAUD 1.79e-26 109.0 4QB0T@10239|Viruses,4QPUT@28883|Caudovirales,4QKQK@10699|Siphoviridae 10699|Siphoviridae S Protein of unknown function (DUF669) - - - - - - - - - - - - - k59_21305_1 2754.EH55_13250 0.000141 54.3 COG0419@1|root,COG3064@1|root,COG3941@1|root,COG0419@2|Bacteria,COG3064@2|Bacteria,COG3941@2|Bacteria 2|Bacteria O tape measure - - 2.1.1.80,3.1.1.61 ko:K03529,ko:K13582,ko:K13924 ko02020,ko02030,ko04112,map02020,map02030,map04112 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035,ko03036 - - - AAA_15,AAA_21 k59_314409_2 1122981.AUME01000026_gene550 0.000238 46.6 COG0553@1|root,COG0553@2|Bacteria,4NG6P@976|Bacteroidetes,2FPNU@200643|Bacteroidia 976|Bacteroidetes L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_156746_1 1028801.RG1141_CH23590 7.42e-48 168.0 COG4422@1|root,COG4422@2|Bacteria,1MXQI@1224|Proteobacteria,2TVMB@28211|Alphaproteobacteria,4BCWQ@82115|Rhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF5131) - - - - - - - - - - - - DUF5131 k59_328077_1 1123269.NX02_21995 2.89e-182 518.0 COG0553@1|root,COG0553@2|Bacteria,1R7CK@1224|Proteobacteria,2U228@28211|Alphaproteobacteria,2KA8N@204457|Sphingomonadales 204457|Sphingomonadales KL DEAD-like helicases superfamily - - - - - - - - - - - - - k59_72908_1 1173023.KE650771_gene3277 7.69e-14 77.4 COG5545@1|root,COG5545@2|Bacteria,1G4RT@1117|Cyanobacteria 1117|Cyanobacteria S Virulence-associated protein E - - - - - - - - - - - - RepB_primase,VirE k59_364528_1 634504.Bgr_07950 1.85e-32 132.0 COG3170@1|root,COG3170@2|Bacteria,1R69E@1224|Proteobacteria,2U3B9@28211|Alphaproteobacteria,48T9Q@772|Bartonellaceae 28211|Alphaproteobacteria NU Phage P22-like portal protein - - - - - - - - - - - - P22_portal k59_24309_1 1692244.A0A0K1RLR5_9CIRC 3.01e-90 275.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_218732_1 105154.Q9MBU0_9VIRU 3.12e-52 176.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_24311_2 929794.CALV01000016_gene160 5.83e-25 106.0 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2TSTN@28211|Alphaproteobacteria,48TJ9@772|Bartonellaceae 28211|Alphaproteobacteria K ParB-like nuclease domain parB - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_157977_1 1618236.A0A0C5IB23_9CIRC 4.48e-15 75.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_157977_2 1618236.A0A0C5IB23_9CIRC 1.49e-15 76.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_121515_3 1150398.JIBJ01000011_gene2316 4.99e-27 110.0 arCOG05626@1|root,2Z9D9@2|Bacteria,2IIAB@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_328082_1 1385658.U5KPZ6_9VIRU 1.21e-144 432.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_340233_1 359.CN09_09375 4.17e-50 172.0 COG0863@1|root,COG0863@2|Bacteria,1PCS4@1224|Proteobacteria,2VDM8@28211|Alphaproteobacteria,4BIRX@82115|Rhizobiaceae 28211|Alphaproteobacteria H DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_340233_2 926560.KE387029_gene76 1.69e-27 105.0 COG1694@1|root,COG1694@2|Bacteria 2|Bacteria FG Mazg nucleotide pyrophosphohydrolase - - - - - - - - - - - - MazG k59_97208_4 1096546.WYO_0183 3.18e-24 99.0 COG1670@1|root,COG1670@2|Bacteria,1PZYK@1224|Proteobacteria,2UN9Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - - - - - - - - - - - k59_97208_6 1217710.F969_00023 3.33e-60 216.0 291GM@1|root,2ZP3A@2|Bacteria,1RD1E@1224|Proteobacteria,1S4X6@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_62029_2 105154.Q9MBU6_9VIRU 3.93e-77 247.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_292734_3 88870.Q9ZX17_BPMT4 3.17e-09 56.6 4QDKR@10239|Viruses,4QX5D@35237|dsDNA viruses no RNA stage,4QR7N@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_341162_1 582402.Hbal_1563 9.14e-31 119.0 COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,2TRJX@28211|Alphaproteobacteria,43X2D@69657|Hyphomonadaceae 28211|Alphaproteobacteria M Belongs to the KdsA family kdsA - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 k59_12966_1 1211777.BN77_4181 8.37e-34 133.0 COG4675@1|root,COG4675@2|Bacteria,1QWQH@1224|Proteobacteria,2UUR5@28211|Alphaproteobacteria,4BFMU@82115|Rhizobiaceae 28211|Alphaproteobacteria S tail collar domain protein - - - - - - - - - - - - Collar k59_122674_1 439235.Dalk_4586 3.3e-51 171.0 2DXZD@1|root,32V4G@2|Bacteria,1N4N1@1224|Proteobacteria,42UVK@68525|delta/epsilon subdivisions,2WQ0A@28221|Deltaproteobacteria,2MPDG@213118|Desulfobacterales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_304874_8 1089546.AQUI01000002_gene1937 3.03e-142 418.0 COG4653@1|root,COG4653@2|Bacteria,2ICZP@201174|Actinobacteria 201174|Actinobacteria S Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_304874_9 1089546.AQUI01000002_gene1936 4.27e-05 52.4 COG3740@1|root,COG3740@2|Bacteria,2H6PF@201174|Actinobacteria 201174|Actinobacteria S Phage prohead protease, HK97 family - - - - - - - - - - - - - k59_317227_2 105154.Q9MBU3_9VIRU 1.04e-19 87.0 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_207855_10 215803.DB30_1125 4.93e-18 97.4 COG1409@1|root,COG1409@2|Bacteria,1N2UT@1224|Proteobacteria,4376F@68525|delta/epsilon subdivisions,2X3M9@28221|Deltaproteobacteria,2YWHB@29|Myxococcales 28221|Deltaproteobacteria S Iron/zinc purple acid phosphatase-like protein C - - - - - - - - - - - - F5_F8_type_C,Metallophos,Metallophos_C k59_207855_15 408672.NBCG_03489 5.91e-61 209.0 COG3227@1|root,COG3227@2|Bacteria,2GJEW@201174|Actinobacteria,4DPG1@85009|Propionibacteriales 201174|Actinobacteria E Thermolysin metallopeptidase, catalytic domain prt1 - - - - - - - - - - - Peptidase_M4,Peptidase_M4_C k59_207855_26 29581.BW37_03941 1.14e-07 61.6 COG2963@1|root,COG2963@2|Bacteria,1PCWW@1224|Proteobacteria,2VKXF@28216|Betaproteobacteria,47377@75682|Oxalobacteraceae 28216|Betaproteobacteria L transposase activity - - - - - - - - - - - - - k59_62179_1 1476391.X5KNB4_9CAUD 1.99e-64 239.0 4QAXA@10239|Viruses,4QYJI@35237|dsDNA viruses no RNA stage,4QQ1A@28883|Caudovirales,4QNU7@10744|Podoviridae 10744|Podoviridae S metallopeptidase activity - - - - - - - - - - - - - k59_25422_16 882.DVU_2152 2.85e-08 63.2 2ANZ0@1|root,31E00@2|Bacteria,1P5IP@1224|Proteobacteria,4330C@68525|delta/epsilon subdivisions,2WXQ3@28221|Deltaproteobacteria,2MFMZ@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_364734_1 634500.EbC_31590 6.49e-10 65.9 COG4675@1|root,COG5301@1|root,COG4675@2|Bacteria,COG5301@2|Bacteria,1QW6Z@1224|Proteobacteria,1T4X6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S tail collar domain protein - - - - - - - - - - - - - k59_194703_2 1788439.A0A190WHD0_9CIRC 1.25e-35 139.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_206835_2 196490.AUEZ01000004_gene3982 0.000518 42.4 COG4653@1|root,COG4653@2|Bacteria,1MXMN@1224|Proteobacteria,2U062@28211|Alphaproteobacteria,3JZTI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_133884_10 398580.Dshi_1907 4.81e-07 59.3 COG4951@1|root,COG4951@2|Bacteria 2|Bacteria - - XK27_08510 - - ko:K06919 - - - - ko00000 - - - DUF1882,Helicase_C,ResIII k59_304067_1 1502851.FG93_01114 5.74e-37 152.0 COG3170@1|root,COG3170@2|Bacteria,1PMRN@1224|Proteobacteria,2VC7S@28211|Alphaproteobacteria,3K5GP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - k59_61030_1 1124982.MSI_25110 8.81e-06 50.4 COG0593@1|root,COG0593@2|Bacteria,2J5F6@203691|Spirochaetes 203691|Spirochaetes L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA - - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k59_146064_3 1121441.AUCX01000013_gene1839 1.31e-53 181.0 COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,42SDU@68525|delta/epsilon subdivisions,2WQ2F@28221|Deltaproteobacteria,2MCVQ@213115|Desulfovibrionales 28221|Deltaproteobacteria H C-5 cytosine-specific DNA methylase dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_316198_2 105154.Q9MBU6_9VIRU 5.75e-202 580.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_73157_1 1096930.L284_16985 2.84e-27 117.0 COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria,2U1JR@28211|Alphaproteobacteria,2K8IS@204457|Sphingomonadales 204457|Sphingomonadales K DNA-directed RNA polymerase N-terminal - - - - - - - - - - - - RNA_pol,RPOL_N k59_328347_1 1141137.K4F7V6_9CAUD 8.16e-83 265.0 4QD9Y@10239|Viruses,4R02G@35237|dsDNA viruses no RNA stage,4QS1V@28883|Caudovirales,4QNWZ@10744|Podoviridae 10744|Podoviridae S Terminase-like family - - - - - - - - - - - - - k59_328402_2 272942.RCAP_rcc02338 2.97e-62 199.0 2BU68@1|root,32PFD@2|Bacteria,1N2SX@1224|Proteobacteria,2UQNX@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_219108_1 1552758.NC00_01260 1.47e-11 70.1 COG3566@1|root,COG3566@2|Bacteria,1REIQ@1224|Proteobacteria,1SZWW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2213) - - - - - - - - - - - - DUF2213 k59_231797_6 469660.A8HNX4_9CAUD 1.44e-31 128.0 4QBFN@10239|Viruses,4QXWN@35237|dsDNA viruses no RNA stage,4QPTW@28883|Caudovirales,4QNPZ@10744|Podoviridae 10744|Podoviridae S Phage stabilisation protein - - - - - - - - - - - - - k59_243865_1 1121272.KB903272_gene531 2.31e-06 53.5 COG0500@1|root,COG2226@2|Bacteria,2I1M7@201174|Actinobacteria,4DG6H@85008|Micromonosporales 201174|Actinobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 k59_195312_1 347834.RHE_CH01103 4.14e-24 101.0 2C22H@1|root,332AB@2|Bacteria,1NBGI@1224|Proteobacteria,2UFBV@28211|Alphaproteobacteria,4BKWG@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - Peptidase_S74 k59_49707_1 478749.BRYFOR_08530 3.32e-18 79.0 2AIHK@1|root,318ZG@2|Bacteria,1V7P0@1239|Firmicutes,24KNU@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_49707_2 691965.D4P7B9_9CAUD 3.61e-25 98.6 4QFDH@10239|Viruses,4QWV5@35237|dsDNA viruses no RNA stage,4QPB8@28883|Caudovirales,4QKNN@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_12911_1 1500894.JQNN01000001_gene4022 1.71e-18 89.0 COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,2VI24@28216|Betaproteobacteria,472I3@75682|Oxalobacteraceae 28216|Betaproteobacteria M Belongs to the SIS family. GutQ KpsF subfamily kdsD - 5.3.1.13 ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CBS,SIS k59_25242_1 1161401.ASJA01000008_gene1658 1.33e-06 54.3 2CJWY@1|root,33MF9@2|Bacteria,1NKUU@1224|Proteobacteria,2UMVZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_73969_1 321846.PS417_10080 2.12e-83 267.0 28KYW@1|root,2ZAE8@2|Bacteria,1MX3D@1224|Proteobacteria,1RQQR@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4055) - - - - - - - - - - - - DUF4055 k59_73969_2 1388763.O165_010685 5.84e-112 337.0 COG2369@1|root,COG2369@2|Bacteria,1PUNX@1224|Proteobacteria,1RUNF@1236|Gammaproteobacteria,1YX7I@136845|Pseudomonas putida group 1236|Gammaproteobacteria S Phage Mu protein F like protein - - - - - - - - - - - - Phage_Mu_F k59_73969_3 1161401.ASJA01000008_gene1658 1.94e-09 62.4 2CJWY@1|root,33MF9@2|Bacteria,1NKUU@1224|Proteobacteria,2UMVZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_134490_1 1692249.A0A0K1RLN8_9CIRC 1.66e-07 55.8 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_219946_1 1234888.K0A2J2_9VIRU 1.65e-105 326.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_243876_2 1316932.MHH_c17580 7.9e-06 47.0 28MEG@1|root,2ZAS3@2|Bacteria,1QJWH@1224|Proteobacteria,1RY3Q@1236|Gammaproteobacteria,1Y859@135625|Pasteurellales 135625|Pasteurellales L YqaJ-like viral recombinase domain - - - - - - - - - - - - YqaJ k59_365289_3 1609634.A0A0C5AFT2_9VIRU 1.3e-125 370.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_365289_5 1609634.A0A0C5AFV4_9VIRU 5.76e-98 302.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_268430_1 1089548.KI783301_gene2694 2.16e-36 149.0 COG4983@1|root,COG5519@1|root,COG4983@2|Bacteria,COG5519@2|Bacteria,1TVU0@1239|Firmicutes,4I496@91061|Bacilli,3WFUJ@539002|Bacillales incertae sedis 91061|Bacilli L DNA primase - - - - - - - - - - - - - k59_365422_1 1692250.A0A0K1RLR1_9CIRC 8.32e-128 372.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_110512_1 15368.BRADI1G31066.1 1.57e-32 134.0 COG5108@1|root,KOG1038@2759|Eukaryota,37Q9S@33090|Viridiplantae,3GFSM@35493|Streptophyta,3KRM5@4447|Liliopsida,3I7G8@38820|Poales 35493|Streptophyta KL DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates - GO:0000428,GO:0000959,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006351,GO:0006390,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009536,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034245,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0098798,GO:0140053,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K00960,ko:K10908 - - - - ko00000,ko01000,ko03029 - - - RNA_pol,RPOL_N k59_293786_1 428125.CLOLEP_01411 8.61e-31 119.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia,3WNJZ@541000|Ruminococcaceae 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_293786_3 428125.CLOLEP_01409 0.0 963.0 COG4626@1|root,COG4626@2|Bacteria,1TT9I@1239|Firmicutes,24AFK@186801|Clostridia,3WNF4@541000|Ruminococcaceae 186801|Clostridia S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_293786_5 411460.RUMTOR_01350 8.2e-05 46.6 2EAAT@1|root,334F2@2|Bacteria,1VJJI@1239|Firmicutes,24TQU@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_26441_1 1541960.KQ78_01196 4.12e-13 73.2 28MKK@1|root,2ZAWR@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_257349_3 1385658.U5KPZ6_9VIRU 5.21e-76 257.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_378802_6 1433126.BN938_0515 1.19e-24 115.0 COG5283@1|root,COG5283@2|Bacteria,4NIZH@976|Bacteroidetes 976|Bacteroidetes D domain protein - - - - - - - - - - - - PhageMin_Tail k59_135794_3 1986029.Q9MBM8_9VIRU 3.94e-48 169.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_160349_2 1121451.DESAM_22746 3.57e-112 350.0 COG5362@1|root,COG5362@2|Bacteria,1PYY9@1224|Proteobacteria,435M3@68525|delta/epsilon subdivisions,2WZZT@28221|Deltaproteobacteria,2M981@213115|Desulfovibrionales 28221|Deltaproteobacteria S TIGRFAM Phage - - - - - - - - - - - - - k59_221256_2 1692253.A0A0K1RLM4_9CIRC 2.58e-31 127.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_378803_1 1234888.K0A2J2_9VIRU 4.37e-85 270.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_50845_1 1504672.669787408 1.25e-75 282.0 COG0553@1|root,COG1040@1|root,COG2263@1|root,COG0553@2|Bacteria,COG1040@2|Bacteria,COG2263@2|Bacteria,1MXQH@1224|Proteobacteria,2WHJ7@28216|Betaproteobacteria 28216|Betaproteobacteria KL methylase - - - - - - - - - - - - - k59_13654_1 1209072.ALBT01000031_gene1886 6.54e-15 83.6 COG2372@1|root,COG3209@1|root,COG2372@2|Bacteria,COG3209@2|Bacteria 2|Bacteria M self proteolysis - - - ko:K07156 - - - - ko00000,ko02000 9.B.62.2 - - Big_5,DUF4082,SLH k59_75072_1 1385658.U5KPZ6_9VIRU 1.19e-115 351.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_75072_3 1165094.RINTHH_3920 1.53e-82 259.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_135803_1 691965.D4P7D6_9CAUD 7.28e-48 172.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_209160_3 1692244.A0A0K1RLR5_9CIRC 5.5e-66 214.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_88432_1 237727.NAP1_12148 1.5e-05 52.0 2DSHN@1|root,33G5Q@2|Bacteria,1NGM3@1224|Proteobacteria,2UK0H@28211|Alphaproteobacteria,2K4KJ@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - k59_161391_4 105154.Q9MBU6_9VIRU 3.67e-157 466.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_161391_5 1609634.A0A0C5ANA6_9VIRU 3.26e-24 102.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_367407_1 691965.D4P7E6_9CAUD 7.38e-26 120.0 4QAK6@10239|Viruses,4R01K@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_125097_2 1444712.BN1013_02394 2.11e-24 100.0 COG4540@1|root,COG4540@2|Bacteria 2|Bacteria L Baseplate assembly protein Z012_12225 - - - - - - - - - - - Phage_base_V k59_294949_1 1089548.KI783301_gene1995 1.46e-08 63.2 COG3864@1|root,COG3864@2|Bacteria,1UZTF@1239|Firmicutes,4I0BT@91061|Bacilli 91061|Bacilli S Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N k59_222337_1 1609634.A0A0C5ANA6_9VIRU 1.09e-07 57.4 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_270420_1 1234888.K0A2J2_9VIRU 7e-36 137.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_3532_1 1618257.A0A0C5IBI9_9CIRC 1.42e-17 84.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_184466_1 484018.BACPLE_00805 9.55e-05 49.3 2EVUA@1|root,33P81@2|Bacteria,4P82D@976|Bacteroidetes,2FV68@200643|Bacteroidia,4AU6A@815|Bacteroidaceae 976|Bacteroidetes - - - - - - - - - - - - - - - k59_246082_2 1609634.A0A0C5AFT2_9VIRU 3.76e-55 189.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_51915_1 105154.Q9MBU6_9VIRU 6.32e-83 263.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_51915_2 105154.Q9MBU3_9VIRU 5.67e-15 75.5 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_283776_2 159087.Daro_2692 2.48e-19 96.7 2DSE3@1|root,33FRF@2|Bacteria,1NKQ7@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_76230_4 686578.AFFX01000018_gene1831 1.07e-20 89.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria 1224|Proteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_197835_1 1618238.A0A0C5I2G8_9CIRC 3.41e-37 140.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_197835_3 46681.XP_001738227.1 6.41e-36 138.0 2CSEE@1|root,2RBK2@2759|Eukaryota,3X9MH@554915|Amoebozoa 554915|Amoebozoa G RNA helicase - - - - - - - - - - - - RNA_helicase k59_40966_2 1254432.SCE1572_26840 6.2e-06 51.6 COG4675@1|root,COG4675@2|Bacteria,1NFWC@1224|Proteobacteria 1224|Proteobacteria S tail collar domain protein - - - - - - - - - - - - Collar k59_296446_1 1609634.A0A0C5AFV4_9VIRU 8.03e-31 125.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_223840_2 289376.THEYE_A0606 2.66e-15 72.0 COG0234@1|root,COG0234@2|Bacteria,3J0RF@40117|Nitrospirae 40117|Nitrospirae O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 k59_235487_1 1379692.S5SXY7_9CIRC 6.68e-13 77.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_102102_1 488538.SAR116_2344 9.85e-09 61.6 2EBZ0@1|root,335Y9@2|Bacteria,1NF45@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_16157_1 1385658.U5KPZ6_9VIRU 1.67e-120 364.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_16157_5 1165094.RINTHH_3920 1.65e-75 240.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_16157_7 1609634.A0A0C5AFV4_9VIRU 8.28e-64 213.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_41149_1 281090.Lxx21550 0.000463 47.0 COG0739@1|root,COG0739@2|Bacteria,2GXEC@201174|Actinobacteria,4FM7P@85023|Microbacteriaceae 201174|Actinobacteria M Peptidase family M23 - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 k59_65958_1 313606.M23134_01127 3.52e-05 55.5 COG3204@1|root,COG3211@1|root,COG4935@1|root,COG3204@2|Bacteria,COG3211@2|Bacteria,COG4935@2|Bacteria,4NJ5V@976|Bacteroidetes,47JPA@768503|Cytophagia 976|Bacteroidetes G Bacterial protein of unknown function (DUF839) - - - ko:K07093 - - - - ko00000 - - - DUF839 k59_199370_2 1235802.C823_03729 9.5e-11 66.6 COG0270@1|root,COG0270@2|Bacteria,1TSNX@1239|Firmicutes,2490C@186801|Clostridia,25WRA@186806|Eubacteriaceae 186801|Clostridia H overlaps another CDS with the same product name - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_163066_1 1609634.A0A0C5AFV4_9VIRU 8.99e-45 162.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_369126_2 1609634.A0A0C5ANA6_9VIRU 1.03e-21 96.3 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_369126_3 1609634.A0A0C5AFV4_9VIRU 1.31e-235 665.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_369126_6 1609634.A0A0C5AFT2_9VIRU 4.11e-19 86.7 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_102300_1 1692246.A0A0K1RL26_9CIRC 2.72e-16 85.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_259846_2 428125.CLOLEP_01411 1.99e-39 146.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia,3WNJZ@541000|Ruminococcaceae 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_235629_3 497964.CfE428DRAFT_5515 3.78e-07 61.6 COG0265@1|root,COG4733@1|root,COG0265@2|Bacteria,COG4733@2|Bacteria,46Z8W@74201|Verrucomicrobia 74201|Verrucomicrobia O Right handed beta helix region - - - - - - - - - - - - Beta_helix k59_90274_2 1282362.AEAC466_04585 1.12e-70 226.0 COG0175@1|root,COG0175@2|Bacteria 2|Bacteria EH sulfate reduction - - - - - - - - - - - - PAPS_reduct k59_346766_1 402612.FP2177 3.84e-39 147.0 COG0714@1|root,COG0714@2|Bacteria,4NJMT@976|Bacteroidetes,1HZMP@117743|Flavobacteriia 976|Bacteroidetes S AAA domain (dynein-related subfamily) - - 6.6.1.2 ko:K09882 ko00860,ko01100,map00860,map01100 - R05227 RC02000 ko00000,ko00001,ko01000 - - - AAA_5 k59_287678_1 1123487.KB892865_gene1394 5.75e-18 84.7 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,2VMZW@28216|Betaproteobacteria 28216|Betaproteobacteria L DNA polymerase family A - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_287678_2 218851.Aquca_011_00564.1 1.4e-08 57.8 COG0484@1|root,KOG0712@2759|Eukaryota,37MSG@33090|Viridiplantae 33090|Viridiplantae O DnaJ protein homolog - - - ko:K09503 ko04141,map04141 - - - ko00000,ko00001,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG k59_287678_4 1382304.JNIL01000001_gene2214 5.14e-06 54.7 28H9V@1|root,2Z7MH@2|Bacteria,1UFFG@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - k59_322765_10 764561.D7RWF9_9CAUD 3.37e-07 59.3 4QBHS@10239|Viruses,4QUVV@35237|dsDNA viruses no RNA stage,4QPT9@28883|Caudovirales,4QKSP@10699|Siphoviridae 10699|Siphoviridae S DNA metabolic process - - - - - - - - - - - - - k59_273792_2 1692259.A0A0K1RL59_9CIRC 1.04e-29 122.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_152502_1 1986029.Q9MBM8_9VIRU 1.93e-42 157.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_103900_1 1158150.KB906242_gene227 3.23e-72 239.0 28IA2@1|root,2Z8CQ@2|Bacteria,1PQM2@1224|Proteobacteria,1SN3W@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_17653_1 487316.BBNM01000015_gene2010 7.27e-41 149.0 COG0338@1|root,COG0338@2|Bacteria,1P85S@1224|Proteobacteria,1RMNW@1236|Gammaproteobacteria,3NMFI@468|Moraxellaceae 1236|Gammaproteobacteria L D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_43014_1 339671.Asuc_1218 1.03e-05 46.6 2EJST@1|root,33DHF@2|Bacteria,1QI8X@1224|Proteobacteria,1TG32@1236|Gammaproteobacteria,1YAP9@135625|Pasteurellales 135625|Pasteurellales S Helix-turn-helix domain - - - - - - - - - - - - HTH_39 k59_43014_3 557598.LHK_01497 2.74e-75 232.0 COG5377@1|root,COG5377@2|Bacteria,1QXZ4@1224|Proteobacteria 1224|Proteobacteria L YqaJ-like viral recombinase domain - - - - - - - - - - - - YqaJ k59_43014_4 1120977.JHUX01000003_gene1774 1.22e-22 96.3 COG0629@1|root,COG0629@2|Bacteria,1RC22@1224|Proteobacteria,1S2A9@1236|Gammaproteobacteria,3NRRN@468|Moraxellaceae 1236|Gammaproteobacteria L ERF superfamily - - - - - - - - - - - - ERF k59_164689_2 1379711.S5TNC7_9CIRC 3.73e-13 73.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_202469_1 11082.PRO_0000037750 6.3e-42 155.0 4QBXT@10239|Viruses,4R138@439488|ssRNA viruses,4R0R1@35278|ssRNA positive-strand viruses no DNA stage 10239|Viruses K ATP-dependent helicase activity - GO:0001510,GO:0001959,GO:0001960,GO:0002682,GO:0002683,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003725,GO:0003727,GO:0003824,GO:0004482,GO:0004483,GO:0005488,GO:0005575,GO:0006139,GO:0006370,GO:0006396,GO:0006397,GO:0006508,GO:0006725,GO:0006807,GO:0006810,GO:0006897,GO:0006898,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008171,GO:0008173,GO:0008174,GO:0008233,GO:0008757,GO:0009451,GO:0009452,GO:0009605,GO:0009607,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009968,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010646,GO:0010648,GO:0010941,GO:0016032,GO:0016070,GO:0016071,GO:0016192,GO:0016556,GO:0016740,GO:0016741,GO:0016787,GO:0018995,GO:0019012,GO:0019031,GO:0019048,GO:0019049,GO:0019050,GO:0019054,GO:0019058,GO:0019065,GO:0019068,GO:0019219,GO:0019222,GO:0019538,GO:0020012,GO:0023051,GO:0023057,GO:0030260,GO:0030430,GO:0030682,GO:0030683,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031347,GO:0031348,GO:0032259,GO:0032991,GO:0032993,GO:0033592,GO:0033643,GO:0033646,GO:0033655,GO:0033668,GO:0034641,GO:0035821,GO:0036260,GO:0036265,GO:0036338,GO:0039502,GO:0039503,GO:0039526,GO:0039713,GO:0039714,GO:0042981,GO:0043067,GO:0043069,GO:0043170,GO:0043207,GO:0043412,GO:0043414,GO:0043487,GO:0043489,GO:0043656,GO:0043657,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044068,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044403,GO:0044409,GO:0044413,GO:0044414,GO:0044415,GO:0044419,GO:0044423,GO:0044501,GO:0044531,GO:0044532,GO:0044766,GO:0045069,GO:0045070,GO:0045088,GO:0045824,GO:0045934,GO:0046483,GO:0046718,GO:0046755,GO:0046762,GO:0046794,GO:0048518,GO:0048519,GO:0048523,GO:0048524,GO:0048583,GO:0048585,GO:0050690,GO:0050776,GO:0050777,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051252,GO:0051253,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051806,GO:0051807,GO:0051817,GO:0051828,GO:0051832,GO:0051833,GO:0051834,GO:0052027,GO:0052029,GO:0052031,GO:0052037,GO:0052040,GO:0052041,GO:0052150,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052248,GO:0052250,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052433,GO:0052490,GO:0052493,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0060147,GO:0060149,GO:0060255,GO:0060338,GO:0060339,GO:0060548,GO:0060759,GO:0060761,GO:0060966,GO:0060967,GO:0060968,GO:0060969,GO:0065007,GO:0065008,GO:0071704,GO:0072583,GO:0075109,GO:0075111,GO:0075112,GO:0075114,GO:0075136,GO:0075509,GO:0075512,GO:0075528,GO:0080009,GO:0080090,GO:0080134,GO:0090304,GO:0097159,GO:0097617,GO:0098657,GO:0106005,GO:0140096,GO:0140098,GO:1900368,GO:1900369,GO:1901360,GO:1901363,GO:1901564,GO:1902369,GO:1902579,GO:1903900,GO:1903902,GO:1990814,GO:1990904 - - - - - - - - - - - k59_18889_1 322855.Q52PN4_9CAUD 2.85e-27 115.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales 28883|Caudovirales S N-methyltransferase activity - - - - - - - - - - - - - k59_250912_1 204669.Acid345_2911 1.09e-112 345.0 COG2304@1|root,COG2304@2|Bacteria,3Y6GT@57723|Acidobacteria,2JKSI@204432|Acidobacteriia 204432|Acidobacteriia S TROVE domain - - - - - - - - - - - - TROVE k59_141860_4 444875.E3SMI1_9CAUD 8.62e-55 198.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_141860_8 986075.CathTA2_1798 2.39e-40 145.0 COG1351@1|root,COG1351@2|Bacteria,1TRHD@1239|Firmicutes,4HTFB@91061|Bacilli 91061|Bacilli F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 k59_141860_9 1327982.R9ZYM1_9CAUD 1.55e-45 154.0 4QD0J@10239|Viruses,4R0A5@35237|dsDNA viruses no RNA stage,4QSK9@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_372316_1 1096546.WYO_0201 1.31e-38 147.0 28P6A@1|root,2ZC10@2|Bacteria,1RBZE@1224|Proteobacteria,2UQEG@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_360056_1 36809.MAB_1796 2.94e-07 62.4 COG0741@1|root,COG3064@1|root,COG5283@1|root,COG5412@1|root,COG0741@2|Bacteria,COG3064@2|Bacteria,COG5283@2|Bacteria,COG5412@2|Bacteria,2I92I@201174|Actinobacteria,239EM@1762|Mycobacteriaceae 201174|Actinobacteria M Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_312118_3 1403313.AXBR01000017_gene3695 7.16e-06 53.1 COG1876@1|root,COG3409@1|root,COG1876@2|Bacteria,COG3409@2|Bacteria,1VC9C@1239|Firmicutes,4HNA4@91061|Bacilli,1ZGE1@1386|Bacillus 91061|Bacilli M D-alanyl-D-alanine carboxypeptidase - - - ko:K17733 - - - - ko00000,ko01000,ko01002,ko01011 - - - PG_binding_1,Peptidase_M15_4 k59_313875_1 391593.RCCS2_17671 4.74e-10 57.8 COG1403@1|root,COG1403@2|Bacteria,1N7SV@1224|Proteobacteria,2UHCG@28211|Alphaproteobacteria 28211|Alphaproteobacteria L HNH nucleases - - - - - - - - - - - - HNH k59_374105_3 1165094.RINTHH_3920 1.14e-67 219.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_217554_2 945543.VIBR0546_06702 5.29e-35 124.0 2AWA7@1|root,31N5R@2|Bacteria,1QJX3@1224|Proteobacteria,1THZ1@1236|Gammaproteobacteria,1XXYM@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - DUF3653 k59_350302_1 1215092.PA6_009_00300 4.16e-49 167.0 28JC4@1|root,2Z96S@2|Bacteria,1RI8W@1224|Proteobacteria,1S6FI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S P22 coat protein-protein 5 domain protein - - - - - - - - - - - - - k59_107073_2 2003327.CAPSD_BPCHP 5.2e-33 132.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_302412_1 1234888.K0A2J2_9VIRU 2.63e-41 153.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_131967_1 530564.Psta_0658 3.99e-72 244.0 COG5362@1|root,COG5362@2|Bacteria,2J0FK@203682|Planctomycetes 203682|Planctomycetes S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_131967_9 1041147.AUFB01000014_gene329 1.88e-23 99.4 2CXZV@1|root,32T32@2|Bacteria,1N4R9@1224|Proteobacteria,2UM96@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_290958_1 691965.D4P7L3_9CAUD 8.51e-141 419.0 4QBH7@10239|Viruses,4QWWF@35237|dsDNA viruses no RNA stage,4QQ8R@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_385991_1 1410619.SRDD_27610 6.54e-07 58.2 COG0840@1|root,COG4733@1|root,COG0840@2|Bacteria,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,1RNFD@1236|Gammaproteobacteria,401CF@613|Serratia 1236|Gammaproteobacteria NT Putative phage tail protein - - - - - - - - - - - - DUF1983,DUF3672,Phage-tail_3 k59_217751_3 1423724.BAMM01000026_gene1991 2.1e-08 58.2 COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,4HAKB@91061|Bacilli,3F4A9@33958|Lactobacillaceae 91061|Bacilli L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity sbcD - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos,SbcD_C k59_386137_2 545243.BAEV01000078_gene3012 2.69e-06 53.5 COG1525@1|root,COG2333@1|root,COG1525@2|Bacteria,COG2333@2|Bacteria,1V8AM@1239|Firmicutes,25BE0@186801|Clostridia,36WHK@31979|Clostridiaceae 186801|Clostridia L Staphylococcal nuclease homologue - - - - - - - - - - - - SNase k59_84714_1 114615.BRADO6930 2.9e-14 70.9 2EHBB@1|root,33B36@2|Bacteria,1RGAQ@1224|Proteobacteria,2U70Q@28211|Alphaproteobacteria,3JZ8Y@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_190011_1 1676988.A0A0H4FNQ1_9CIRC 2.82e-21 95.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_190011_3 1618241.A0A0C5I2I4_9CIRC 5.08e-70 222.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_351733_3 1231190.NA8A_23409 9.54e-12 66.6 COG4122@1|root,COG4122@2|Bacteria,1QWQR@1224|Proteobacteria,2TX2B@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Methyltransferase domain - - - - - - - - - - - - Methyltransf_24 k59_230848_2 1089551.KE386572_gene4718 2.19e-69 224.0 28HS3@1|root,2Z7ZE@2|Bacteria,1QH9A@1224|Proteobacteria,2TVB0@28211|Alphaproteobacteria,4BR65@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_265929_1 1005048.CFU_0041 1.4e-45 155.0 COG0279@1|root,COG0279@2|Bacteria,1NVIE@1224|Proteobacteria,2W93C@28216|Betaproteobacteria,47711@75682|Oxalobacteraceae 28216|Betaproteobacteria G SIS domain - - 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 - - - SIS_2 k59_351736_1 1298867.AUES01000093_gene3157 2.04e-50 173.0 COG5545@1|root,COG5545@2|Bacteria,1MVGK@1224|Proteobacteria,2U0ID@28211|Alphaproteobacteria,3JWBU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Virulence-associated protein E - - - - - - - - - - - - Prim-Pol,Toprim_3,VirE k59_169094_1 768066.HELO_2662 1.59e-21 96.3 COG0338@1|root,COG0338@2|Bacteria 2|Bacteria L D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_60295_1 1234888.K0A2R8_9VIRU 1.64e-25 105.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_60295_2 1234888.K0A2J2_9VIRU 6.51e-177 512.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_169269_1 742823.HMPREF9465_01261 3.2e-18 91.7 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,2VMZW@28216|Betaproteobacteria 28216|Betaproteobacteria L DNA polymerase family A - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_363226_1 1385658.U5KPZ6_9VIRU 2.7e-90 284.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_84923_1 1236504.HMPREF2132_11055 3.61e-30 115.0 COG0827@1|root,COG0827@2|Bacteria,4P741@976|Bacteroidetes,2FVWI@200643|Bacteroidia 976|Bacteroidetes L DNA restriction-modification system - - - - - - - - - - - - - k59_267331_18 1188795.K7ZMK0_9CAUD 5.21e-50 176.0 4QE1R@10239|Viruses,4R08Y@35237|dsDNA viruses no RNA stage,4QUAF@28883|Caudovirales,4QNMU@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_267331_47 1472716.KBK24_0121465 2.54e-42 149.0 COG2214@1|root,COG2214@2|Bacteria,1N1HS@1224|Proteobacteria,2W2UD@28216|Betaproteobacteria,1KA00@119060|Burkholderiaceae 28216|Betaproteobacteria O DnaJ molecular chaperone homology domain - - - - - - - - - - - - - k59_267331_51 592316.Pat9b_2142 3.16e-42 142.0 COG4570@1|root,COG4570@2|Bacteria,1RH5J@1224|Proteobacteria,1S7I6@1236|Gammaproteobacteria 1236|Gammaproteobacteria L endodeoxyribonuclease RusA - - - - - - - - - - - - RusA k59_267331_57 1396141.BATP01000029_gene2258 4.39e-48 166.0 2E0FE@1|root,32W1M@2|Bacteria,46TEN@74201|Verrucomicrobia,2IVPU@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_267331_62 913865.DOT_1568 1.47e-111 332.0 28MC2@1|root,2ZAQD@2|Bacteria,1VSEU@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - k59_267331_64 699218.HMPREF0889_0289 3.31e-18 90.5 COG0507@1|root,COG0507@2|Bacteria,1TQWH@1239|Firmicutes,4H656@909932|Negativicutes 909932|Negativicutes L Terminase RNaseH-like domain - - - - - - - - - - - - - k59_376847_4 110365.A0A023B1R5 1.72e-06 52.8 2EWQP@1|root,2SYH6@2759|Eukaryota 2759|Eukaryota S RNA helicase - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_376847_5 1379717.S5SY19_9CIRC 0.000993 47.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_340331_13 89187.ISM_05190 5.13e-16 85.5 COG5281@1|root,COG5281@2|Bacteria,1R47M@1224|Proteobacteria,2TUIV@28211|Alphaproteobacteria,46QA2@74030|Roseovarius 28211|Alphaproteobacteria S COG5281 Phage-related minor tail protein - - - - - - - - - - - - - k59_170266_1 105154.Q9MBU3_9VIRU 2.04e-05 51.6 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_303927_1 388401.RB2150_04318 9.91e-28 114.0 COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,3ZIC4@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_97292_1 1609634.A0A0C5AFV4_9VIRU 1.65e-139 413.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_97292_3 1986029.Q9MBM3_9VIRU 6.48e-38 141.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_97292_6 1609634.A0A0C5ANA6_9VIRU 3e-18 86.7 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_207164_3 329254.Q2NPF7_9CAUD 1.99e-28 108.0 4QB0U@10239|Viruses,4QZQJ@35237|dsDNA viruses no RNA stage,4QR5X@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_219357_3 216142.LT40_12420 6.35e-21 94.0 COG2404@1|root,COG2404@2|Bacteria,1MXEH@1224|Proteobacteria,1SADM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S phosphoesterase DHHA1 - - - - - - - - - - - - DHHA1 k59_316439_2 279238.Saro_3004 2.4e-222 628.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,2U0EG@28211|Alphaproteobacteria,2KC8R@204457|Sphingomonadales 204457|Sphingomonadales S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6C k59_182644_4 105154.Q9MBU0_9VIRU 6.94e-65 213.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_182644_6 1609634.A0A0C5AFV4_9VIRU 6.45e-184 533.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_292117_1 1636270.A0A0E3M0Y6_9CAUD 6.9e-12 73.9 4QBD3@10239|Viruses,4QQ7Z@28883|Caudovirales,4QNJ0@10744|Podoviridae 10744|Podoviridae S P22 coat protein - gene protein 5 - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0009987,GO:0016032,GO:0016043,GO:0019012,GO:0019028,GO:0019030,GO:0019058,GO:0019068,GO:0019069,GO:0019075,GO:0022607,GO:0039620,GO:0042802,GO:0042803,GO:0044085,GO:0044403,GO:0044419,GO:0044423,GO:0046729,GO:0046797,GO:0046983,GO:0051704,GO:0071840 - - - - - - - - - - - k59_97682_1 1382230.ASAP_0509 4.06e-34 131.0 COG0582@1|root,COG0582@2|Bacteria,1R3TM@1224|Proteobacteria,2TS94@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k59_377242_4 656024.FsymDg_4554 3.18e-17 79.7 COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,4ESDK@85013|Frankiales 201174|Actinobacteria L PFAM single-strand binding protein Primosomal replication protein n ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_340597_1 439235.Dalk_4556 5.83e-27 112.0 28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria,42QIP@68525|delta/epsilon subdivisions,2WKTY@28221|Deltaproteobacteria,2MME2@213118|Desulfobacterales 28221|Deltaproteobacteria S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_340597_3 1121033.AUCF01000044_gene4597 1.52e-13 82.4 COG0457@1|root,COG0457@2|Bacteria,1MUZK@1224|Proteobacteria,2TS0U@28211|Alphaproteobacteria,2JPRT@204441|Rhodospirillales 204441|Rhodospirillales M Tetratricopeptide repeat - - - - - - - - - - - - Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8 k59_340597_4 395495.Lcho_0484 2.98e-25 106.0 COG2227@1|root,COG2520@1|root,COG2227@2|Bacteria,COG2520@2|Bacteria 2|Bacteria J tRNA (guanine(37)-N(1))-methyltransferase activity - - - - - - - - - - - - Glycos_transf_2,Methyltransf_11,Methyltransf_21,Methyltransf_23,Methyltransf_25 k59_220237_1 1692256.A0A0K1RL85_9CIRC 9.79e-25 100.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_220237_3 1692252.A0A0K1RL35_9CIRC 5.01e-73 229.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_195658_4 521674.Plim_2126 1.67e-24 104.0 2EEBY@1|root,33868@2|Bacteria,2J2V3@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_341438_3 1123269.NX02_21910 8.97e-06 49.3 299N2@1|root,2ZWQE@2|Bacteria,1NK8N@1224|Proteobacteria,2V0UA@28211|Alphaproteobacteria,2K82Y@204457|Sphingomonadales 204457|Sphingomonadales S Bacteriophage HK97-gp10, putative tail-component - - - - - - - - - - - - HK97-gp10_like k59_256538_1 1379717.S5SY19_9CIRC 2.21e-43 160.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_365688_1 552811.Dehly_1219 4.84e-09 54.3 COG0789@1|root,COG0789@2|Bacteria,2G9W3@200795|Chloroflexi,34DHG@301297|Dehalococcoidia 301297|Dehalococcoidia K Helix-turn-helix domain - - - - - - - - - - - - HTH_17 k59_123007_4 525282.HMPREF0391_10171 9.76e-21 100.0 COG2887@1|root,COG2887@2|Bacteria,1TPIC@1239|Firmicutes,247TB@186801|Clostridia,22H2H@1570339|Peptoniphilaceae 186801|Clostridia L Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_244205_3 105154.Q9MBU2_9VIRU 1.21e-14 73.9 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_341441_2 1122611.KB903985_gene3791 5.99e-06 49.3 COG0451@1|root,COG0451@2|Bacteria,2GMHH@201174|Actinobacteria,4EPFD@85012|Streptosporangiales 201174|Actinobacteria M RmlD substrate binding domain - GO:0000166,GO:0003674,GO:0003824,GO:0003854,GO:0004769,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0016020,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016853,GO:0016860,GO:0016863,GO:0030283,GO:0033764,GO:0036094,GO:0043167,GO:0043168,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901360,GO:1901363 1.1.1.145,1.1.1.412,5.3.3.1 ko:K16045,ko:K22320 ko00984,ko01120,map00984,map01120 - R09920 RC00146 ko00000,ko00001,ko01000 - - - 3Beta_HSD,Epimerase k59_13124_2 1618257.A0A0C5IBI9_9CIRC 8.09e-31 119.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_1434_2 742767.HMPREF9456_03236 1.08e-68 228.0 COG1783@1|root,COG1783@2|Bacteria,4NHPB@976|Bacteroidetes,2FR95@200643|Bacteroidia,22WQM@171551|Porphyromonadaceae 976|Bacteroidetes S Terminase RNAseH like domain - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_317479_1 1429767.W6ASL7_9CAUD 1.78e-37 141.0 4QAR1@10239|Viruses,4QUNA@35237|dsDNA viruses no RNA stage,4QPJE@28883|Caudovirales,4QNDS@10744|Podoviridae 10744|Podoviridae S ATPase activity - - - - - - - - - - - - - k59_98592_1 1234888.K0A2J2_9VIRU 2.86e-27 111.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_98592_7 2003327.CAPSD_BPCHP 3.3e-29 127.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_379025_2 74547.PMT_0778 1.17e-17 83.2 COG1573@1|root,COG1573@2|Bacteria,1FZYH@1117|Cyanobacteria,1MMHR@1212|Prochloraceae 1117|Cyanobacteria L Alternative locus ID - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_136041_2 575540.Isop_3007 1.68e-05 49.7 COG0727@1|root,COG0727@2|Bacteria,2IZM1@203682|Planctomycetes 203682|Planctomycetes S Putative zinc- or iron-chelating domain - - - ko:K06940 - - - - ko00000 - - - CxxCxxCC k59_209379_1 583355.Caka_2962 4.62e-22 98.6 COG1475@1|root,COG1475@2|Bacteria,46UYR@74201|Verrucomicrobia 74201|Verrucomicrobia K ParB-like nuclease domain - - - - - - - - - - - - ParBc k59_209379_5 1187128.I2GUC6_9CAUD 2.51e-15 75.9 4QBHW@10239|Viruses,4QW8N@35237|dsDNA viruses no RNA stage,4QTT7@28883|Caudovirales,4QJZQ@10662|Myoviridae 10662|Myoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_87475_1 105154.Q9MBU6_9VIRU 8.22e-209 598.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_87475_3 1385658.U5KNR1_9VIRU 9.05e-64 209.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_318709_1 1636271.A0A0E3M3Z1_9CAUD 6.28e-71 225.0 4QAIK@10239|Viruses,4QPEB@28883|Caudovirales,4QKNC@10699|Siphoviridae 10699|Siphoviridae S hydrolase activity - - - - - - - - - - - - - k59_342569_1 1144310.PMI07_002360 0.000283 50.4 2DPZ1@1|root,3340X@2|Bacteria,1R2EE@1224|Proteobacteria,2TZIB@28211|Alphaproteobacteria,4BP2Q@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_354898_2 196490.AUEZ01000004_gene3924 1.59e-08 61.6 2E9NZ@1|root,333VE@2|Bacteria,1RIJ2@1224|Proteobacteria,2UB3M@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PDDEXK-like domain of unknown function (DUF3799) - - - - - - - - - - - - DUF3799 k59_38662_15 748727.CLJU_c03600 7.35e-14 73.9 2CK39@1|root,32SBG@2|Bacteria,1V8KG@1239|Firmicutes,249UQ@186801|Clostridia,36M4S@31979|Clostridiaceae 186801|Clostridia S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 k59_38662_17 237609.PSAKL28_17040 1.05e-85 274.0 COG4653@1|root,COG4653@2|Bacteria,1MWU1@1224|Proteobacteria,1S0F5@1236|Gammaproteobacteria 1236|Gammaproteobacteria S capsid protein - - - - - - - - - - - - Phage_capsid k59_38662_18 1229783.C273_01735 5.67e-23 103.0 COG0740@1|root,COG0740@2|Bacteria,1TR2H@1239|Firmicutes,4HD7V@91061|Bacilli,4GZII@90964|Staphylococcaceae 91061|Bacilli OU Belongs to the peptidase S14 family - - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease k59_38662_20 467481.B0VK31_9CAUD 2.78e-52 183.0 4QAYV@10239|Viruses,4QUZ7@35237|dsDNA viruses no RNA stage,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - k59_26794_2 1234888.K0A2J2_9VIRU 2.95e-129 389.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_27817_1 477974.Daud_1260 2.15e-08 64.3 COG3864@1|root,COG3864@2|Bacteria,1UZTF@1239|Firmicutes,259MR@186801|Clostridia,263AP@186807|Peptococcaceae 186801|Clostridia S Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N k59_112760_1 948071.S4S2D9_9CAUD 9.32e-160 469.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae 10744|Podoviridae S ribonucleoside-triphosphate reductase activity - - - - - - - - - - - - - k59_112760_4 1141106.CAIB01000118_gene947 3.01e-06 47.4 29R18@1|root,30C2C@2|Bacteria,1W3U4@1239|Firmicutes,4I259@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - k59_112760_5 373994.Riv7116_5755 2.95e-16 75.5 COG1694@1|root,COG1694@2|Bacteria,1GA07@1117|Cyanobacteria 1117|Cyanobacteria S Pyrophosphatase - - - - - - - - - - - - MazG k59_161625_1 745776.DGo_CA1893 8.35e-21 95.5 COG4653@1|root,COG4653@2|Bacteria 2|Bacteria G Phage capsid family xkdG - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_149215_1 1788444.A0A190WHB9_9CIRC 1.92e-45 161.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_39631_1 1197951.I6R9K8_9CAUD 1.59e-71 227.0 4QFIC@10239|Viruses,4QXG2@35237|dsDNA viruses no RNA stage,4QTVA@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_197901_1 1192759.AKIB01000023_gene2889 3.64e-42 151.0 28W6R@1|root,2ZI7D@2|Bacteria,1N49N@1224|Proteobacteria,2UQMC@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_380267_1 759938.F5BSB4_9CIRC 4.51e-37 144.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_88743_1 1165094.RINTHH_3920 2.59e-65 214.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_27948_1 691965.D4P7D6_9CAUD 3.83e-61 214.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_14919_1 1489678.RDMS_01640 3.62e-29 122.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria 2|Bacteria K chromosome segregation - - - - - - - - - - - - Terminase_6,Terminase_6C k59_295293_11 1028801.RG1141_CH24350 1.51e-11 71.6 COG4422@1|root,COG4422@2|Bacteria,1MXQI@1224|Proteobacteria,2TVMB@28211|Alphaproteobacteria,4BCWQ@82115|Rhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF5131) - - - - - - - - - - - - DUF5131 k59_101024_4 1209989.TepiRe1_0137 5.97e-06 47.4 COG1396@1|root,COG1396@2|Bacteria,1VGK2@1239|Firmicutes,25G5R@186801|Clostridia,42J7R@68295|Thermoanaerobacterales 186801|Clostridia K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 k59_14921_1 360910.BAV0429 2.75e-20 94.7 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,2VSX1@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_40996_1 1094560.ME9_00022 1.05e-06 51.2 COG3170@1|root,COG3170@2|Bacteria,1R69E@1224|Proteobacteria,2U3B9@28211|Alphaproteobacteria,48TPA@772|Bartonellaceae 28211|Alphaproteobacteria NU Phage P22-like portal protein - - - - - - - - - - - - P22_portal k59_40996_2 697281.Mahau_0077 1.92e-19 92.4 COG0507@1|root,COG0507@2|Bacteria,1TQWH@1239|Firmicutes,24A8I@186801|Clostridia,42HVJ@68295|Thermoanaerobacterales 186801|Clostridia L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - - - - - - - - - - - k59_138357_1 1219035.NT2_13_00580 5.57e-77 250.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_65806_1 545695.TREAZ_0592 5.32e-40 150.0 COG1196@1|root,COG1196@2|Bacteria 2|Bacteria D nuclear chromosome segregation - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - Dam,PhageMin_Tail k59_53387_2 1379718.S5TMX4_9CIRC 5.35e-80 251.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_162902_1 292414.TM1040_0783 9.12e-46 156.0 2DIG9@1|root,3036R@2|Bacteria,1RBPA@1224|Proteobacteria,2U6EP@28211|Alphaproteobacteria 28211|Alphaproteobacteria L YqaJ-like viral recombinase domain - - - - - - - - - - - - YqaJ k59_296482_2 195105.CN97_00640 1.1e-40 143.0 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2U7X4@28211|Alphaproteobacteria 28211|Alphaproteobacteria G lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_381466_2 1537917.JU82_03700 4.76e-82 258.0 COG0553@1|root,COG0553@2|Bacteria 2|Bacteria L helicase activity - - - - - - - - - - - - Helicase_C,PLDc_2,ResIII,SNF2_N k59_259721_3 869209.Tresu_1987 1.2e-29 117.0 COG0270@1|root,COG0270@2|Bacteria,2J8AP@203691|Spirochaetes 2|Bacteria H PFAM C-5 cytosine-specific DNA methylase dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_223871_1 95619.PM1_0200065 6.25e-38 132.0 COG1598@1|root,COG1598@2|Bacteria,1N3KE@1224|Proteobacteria,1S32S@1236|Gammaproteobacteria 1236|Gammaproteobacteria K HicB_like antitoxin of bacterial toxin-antitoxin system - - - - - - - - - - - - HicB_lk_antitox k59_223871_2 520709.F985_01923 3.23e-27 99.8 COG1724@1|root,COG1724@2|Bacteria,1N7S3@1224|Proteobacteria,1SE2D@1236|Gammaproteobacteria,3NQ4A@468|Moraxellaceae 1236|Gammaproteobacteria N HicA toxin of bacterial toxin-antitoxin, - - - - - - - - - - - - HicA_toxin k59_211995_1 743721.Psesu_1508 5.81e-12 77.0 COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1MX5Z@1224|Proteobacteria,1RMDY@1236|Gammaproteobacteria,1X3ND@135614|Xanthomonadales 135614|Xanthomonadales M Glycosyltransferases involved in cell wall biogenesis - - - ko:K20444 - - - - ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 - Glycos_transf_2 k59_113866_1 698486.D2XJ98_9CAUD 3.43e-26 107.0 4QVZ9@35237|dsDNA viruses no RNA stage,4QPXI@28883|Caudovirales 28883|Caudovirales S C-5 cytosine-specific DNA methylase - - - - - - - - - - - - - k59_164342_2 1535422.ND16A_0512 4.12e-18 92.8 COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,2Q6A7@267889|Colwelliaceae 1236|Gammaproteobacteria L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN GO:0003674,GO:0003824,GO:0003887,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0022616,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 k59_287419_1 526227.Mesil_1223 3.75e-51 171.0 COG4932@1|root,COG4932@2|Bacteria 2|Bacteria M domain protein - - - - - - - - - - - - CarboxypepD_reg,DUF11,SdrD_B,SprB k59_176681_1 1385658.U5KPZ6_9VIRU 3.16e-90 283.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_115273_2 1636271.A0A0E3M3Z1_9CAUD 4.72e-69 226.0 4QAIK@10239|Viruses,4QPEB@28883|Caudovirales,4QKNC@10699|Siphoviridae 10699|Siphoviridae S hydrolase activity - - - - - - - - - - - - - k59_358481_1 1205680.CAKO01000042_gene5487 7.98e-65 214.0 28MEU@1|root,2ZASF@2|Bacteria,1R7N3@1224|Proteobacteria 1224|Proteobacteria S TIGRFAM Phage recombination protein Bet - - - - - - - - - - - - RecT k59_249332_1 1280944.HY17_04705 6.37e-12 75.5 2E8SI@1|root,3333B@2|Bacteria,1N7MG@1224|Proteobacteria,2UJSF@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_6568_1 459349.CLOAM0520 0.000628 48.1 COG1404@1|root,COG4733@1|root,COG4932@1|root,COG1404@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria,2NREM@2323|unclassified Bacteria 2|Bacteria O Evidence 5 No homology to any previously reported sequences J - - ko:K14194,ko:K21449 ko05150,map05150 - - - ko00000,ko00001,ko02000 1.B.40.2 - - DUF1983,DUF3672,Phage-tail_3,SdrD_B k59_128212_1 1206739.BAGJ01000262_gene2948 2.98e-14 79.3 COG1783@1|root,COG1783@2|Bacteria,2I8SC@201174|Actinobacteria,4FXUD@85025|Nocardiaceae 201174|Actinobacteria S Terminase-like family - - - - - - - - - - - - Terminase_3,Terminase_6,Terminase_6C k59_152430_1 1088721.NSU_0291 6.03e-99 300.0 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,2TQWC@28211|Alphaproteobacteria,2KBNR@204457|Sphingomonadales 204457|Sphingomonadales L UvrD-like helicase C-terminal domain - - - - - - - - - - - - AAA_30,UvrD_C_2 k59_200880_1 243090.RB11607 0.000995 47.8 COG5373@1|root,COG5373@2|Bacteria,2J3V5@203682|Planctomycetes 203682|Planctomycetes S SLA1 homology domain 1, SHD1 - - - - - - - - - - - - SHD1 k59_54977_1 1618248.A0A0C5IB82_9CIRC 1.81e-17 81.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_54977_2 1692242.A0A0K1RKZ2_9CIRC 1.75e-07 60.1 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_54977_3 1692250.A0A0K1RLR1_9CIRC 2.7e-88 270.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_336256_1 1122137.AQXF01000001_gene2540 1.68e-19 89.7 COG3756@1|root,COG3756@2|Bacteria,1NGB2@1224|Proteobacteria,2VGAH@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF1376) - - - - - - - - - - - - DUF1376 k59_129723_1 1175654.A0A0S0N897_9CAUD 1.01e-50 179.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_116856_1 285535.JOEY01000026_gene9031 7.89e-42 155.0 COG4653@1|root,COG4653@2|Bacteria,2I9AZ@201174|Actinobacteria 201174|Actinobacteria S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_227142_2 1385658.U5KPZ6_9VIRU 1.27e-96 301.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_336262_1 1109715.G9FHU3_9CAUD 3.76e-15 73.6 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QPEB@28883|Caudovirales,4QKT0@10699|Siphoviridae 10699|Siphoviridae S Recombination endonuclease VII - - - - - - - - - - - - - k59_165821_2 1317118.ATO8_18655 1.65e-10 63.5 2E5ZV@1|root,330P8@2|Bacteria,1NFRE@1224|Proteobacteria,2UHQQ@28211|Alphaproteobacteria,4KNZP@93682|Roseivivax 28211|Alphaproteobacteria S Domain of unknown function (DUF1833) - - - - - - - - - - - - DUF1833 k59_178443_1 1121918.ARWE01000001_gene770 9.26e-125 383.0 COG5511@1|root,COG5511@2|Bacteria,1MVN4@1224|Proteobacteria,43A5E@68525|delta/epsilon subdivisions,2X2KA@28221|Deltaproteobacteria,43VVQ@69541|Desulfuromonadales 28221|Deltaproteobacteria S Phage portal protein, lambda family - - - - - - - - - - - - Phage_portal_2 k59_178443_2 589873.EP13_09080 1.97e-15 87.4 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNYW@1236|Gammaproteobacteria,46415@72275|Alteromonadaceae 1236|Gammaproteobacteria OU COG0616 Periplasmic serine proteases (ClpP class) sppA GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016485,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 k59_178443_19 1266908.AQPB01000051_gene2445 1.54e-13 68.2 2AT0I@1|root,31IGD@2|Bacteria,1NAE0@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_250799_4 290633.GOX2545 5.3e-105 318.0 COG0175@1|root,COG0175@2|Bacteria,1R55Q@1224|Proteobacteria,2UC3A@28211|Alphaproteobacteria,2JURS@204441|Rhodospirillales 204441|Rhodospirillales EH Phosphoadenosine phosphosulfate reductase family - - - - - - - - - - - - PAPS_reduct k59_56448_1 488538.SAR116_0176 3.76e-35 141.0 COG3598@1|root,COG3598@2|Bacteria,1PG3F@1224|Proteobacteria,2V9QM@28211|Alphaproteobacteria,4BSBX@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria L AAA domain - - - - - - - - - - - - AAA_25 k59_324278_1 1385658.U5KPZ6_9VIRU 1.14e-80 258.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_82587_1 428125.CLOLEP_01422 3.61e-13 78.6 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,3WN92@541000|Ruminococcaceae 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_290630_1 243273.MG_339 9.33e-07 52.4 COG0468@1|root,COG0468@2|Bacteria,3WSYY@544448|Tenericutes 544448|Tenericutes L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA - - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA k59_290630_2 638303.Thal_0552 3.08e-05 52.8 COG0420@1|root,COG0420@2|Bacteria,2G45D@200783|Aquificae 200783|Aquificae L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity sbcD - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos k59_188626_1 742733.HMPREF9469_05020 1.44e-54 194.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,221IX@1506553|Lachnoclostridium 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_131447_1 479434.Sthe_1596 6.29e-41 153.0 COG0305@1|root,COG0305@2|Bacteria,2G64D@200795|Chloroflexi,27XKA@189775|Thermomicrobia 189775|Thermomicrobia L Participates in initiation and elongation during chromosome replication - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_252367_1 870967.VIS19158_08213 2.69e-29 118.0 COG0433@1|root,COG0433@2|Bacteria,1QTVP@1224|Proteobacteria,1T1IQ@1236|Gammaproteobacteria,1XY9N@135623|Vibrionales 135623|Vibrionales S Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_203931_1 1128073.G9LQV6_9CIRC 2.6e-11 68.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_167220_8 909663.KI867149_gene3268 1.56e-17 81.3 COG3772@1|root,COG3772@2|Bacteria,1N0ZQ@1224|Proteobacteria,42V55@68525|delta/epsilon subdivisions,2WSE7@28221|Deltaproteobacteria 28221|Deltaproteobacteria S lysozyme - - - - - - - - - - - - - k59_349821_1 1618260.A0A0C5I2C5_9CIRC 8.92e-88 267.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_95461_1 697282.Mettu_1302 4.46e-50 171.0 COG0535@1|root,COG0535@2|Bacteria,1PHAQ@1224|Proteobacteria 1224|Proteobacteria C Radical SAM - - - - - - - - - - - - Fer4_14,Radical_SAM,SPASM k59_229090_1 1234888.K0A2J2_9VIRU 2.85e-58 199.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_20498_1 626418.bglu_1g15490 7.5e-18 82.0 COG4570@1|root,COG4570@2|Bacteria,1N32D@1224|Proteobacteria,2VSY6@28216|Betaproteobacteria,1K929@119060|Burkholderiaceae 28216|Betaproteobacteria L Endodeoxyribonuclease RusA - - - - - - - - - - - - RusA k59_46127_1 1116369.KB890024_gene186 4.83e-49 166.0 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2UDUF@28211|Alphaproteobacteria 28211|Alphaproteobacteria G lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_218699_10 118166.JH976537_gene3388 3.19e-13 81.3 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1G1P1@1117|Cyanobacteria,1H8EM@1150|Oscillatoriales 1117|Cyanobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_218699_12 1128421.JAGA01000003_gene3720 1.21e-12 74.3 COG1573@1|root,COG1573@2|Bacteria,2NP99@2323|unclassified Bacteria 2|Bacteria L Uracil DNA glycosylase superfamily - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_218699_13 1410618.JNKI01000018_gene1938 1.41e-13 79.7 COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,4H2P0@909932|Negativicutes 909932|Negativicutes K Belongs to the ParB family spo0J - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_59745_1 226185.EF_1455 3.2e-39 151.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1TSMG@1239|Firmicutes,4HBFH@91061|Bacilli,4B0TG@81852|Enterococcaceae 91061|Bacilli S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_119908_1 351348.Maqu_1500 2.42e-109 332.0 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RMJ1@1236|Gammaproteobacteria,465VD@72275|Alteromonadaceae 1236|Gammaproteobacteria L Arm DNA-binding domain - - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k59_362676_1 1498011.A0A096XUS7_9CAUD 3.03e-52 184.0 4QAUF@10239|Viruses,4QQIV@28883|Caudovirales,4QNZ6@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_144982_1 435591.BDI_0861 1.89e-52 182.0 COG0270@1|root,COG0270@2|Bacteria,4NJPP@976|Bacteroidetes,2FKYT@200643|Bacteroidia 976|Bacteroidetes H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_84359_1 1123288.SOV_4c02490 1.89e-28 113.0 COG0270@1|root,COG0270@2|Bacteria,1TPNE@1239|Firmicutes 1239|Firmicutes H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family ydiP - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_327544_2 213236.Q716M7_9CAUD 9.95e-08 56.2 4QD1E@10239|Viruses,4QZVF@35237|dsDNA viruses no RNA stage,4QQTH@28883|Caudovirales,4QN2P@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_254038_1 1122611.KB903985_gene3819 3.48e-41 150.0 COG0451@1|root,COG0451@2|Bacteria,2IDID@201174|Actinobacteria 201174|Actinobacteria GM GDP-mannose 4,6 dehydratase - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase k59_387073_1 1379695.S5TNA9_9CIRC 2.84e-06 52.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_362679_1 1381123.AYOD01000005_gene1290 1.17e-54 186.0 2CHRY@1|root,30Z9E@2|Bacteria,1RGQK@1224|Proteobacteria,2U9J0@28211|Alphaproteobacteria,43MIB@69277|Phyllobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - RecT k59_181754_1 913183.E5RUZ8_9CAUD 1.29e-42 159.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_157425_1 1609634.A0A0C5AFV4_9VIRU 1.77e-90 282.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_339667_1 1502851.FG93_01932 3.43e-14 81.6 2DPZ1@1|root,3340X@2|Bacteria,1R2EE@1224|Proteobacteria,2TZIB@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_241659_1 1618248.A0A0C5IB82_9CIRC 6.6e-97 295.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_254046_1 1526550.A0A088F6W1_9VIRU 8.57e-24 107.0 4QAK6@10239|Viruses 10239|Viruses S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_119923_1 2003327.CAPSD_BPCHP 1.49e-11 70.5 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_375284_2 105154.Q9MBU6_9VIRU 3.27e-227 644.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_375284_3 105154.Q9MBU3_9VIRU 8.72e-14 75.5 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_10655_1 105154.Q9MBU6_9VIRU 3.73e-61 206.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_230559_2 743721.Psesu_1130 2.33e-32 124.0 28KIJ@1|root,2ZA3S@2|Bacteria,1R4PD@1224|Proteobacteria,1SKVF@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_59775_1 186617.M9M8L2_9VIRU 1.89e-63 211.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_388630_2 1618242.A0A0C5IBR9_9CIRC 2.66e-38 143.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_192917_2 8083.ENSXMAP00000001833 1.05e-10 66.2 28M3E@1|root,2QTK7@2759|Eukaryota,38HMQ@33154|Opisthokonta,3BA75@33208|Metazoa,3CTGH@33213|Bilateria,4886Y@7711|Chordata,48VFU@7742|Vertebrata,49T8C@7898|Actinopterygii 33208|Metazoa O beta-1,4-N-acetyl-galactosaminyl transferase B4GALNT1 GO:0000003,GO:0000139,GO:0001573,GO:0001574,GO:0003674,GO:0003824,GO:0003947,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006688,GO:0006807,GO:0007276,GO:0007283,GO:0008150,GO:0008152,GO:0008194,GO:0008376,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0010876,GO:0012505,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019915,GO:0019953,GO:0022414,GO:0030148,GO:0031090,GO:0031984,GO:0032501,GO:0032504,GO:0033036,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044422,GO:0044424,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0046467,GO:0046513,GO:0048232,GO:0048609,GO:0051179,GO:0051235,GO:0051704,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:0098588,GO:0098791,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.4.1.92 ko:K00725,ko:K09655 ko00604,ko01100,map00604,map01100 - R05938,R05939,R05946,R05952,R07609 - ko00000,ko00001,ko01000,ko01003 - GT12 - Glycos_transf_2 k59_192935_1 1506994.JNLQ01000002_gene3109 3.52e-19 90.5 2DN9Q@1|root,32WAD@2|Bacteria,1VRWI@1239|Firmicutes,24ZBK@186801|Clostridia,4BWQI@830|Butyrivibrio 186801|Clostridia - - - - - - - - - - - - - - - k59_193010_2 1609634.A0A0C5AFT2_9VIRU 1.04e-45 159.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_193024_1 937777.Deipe_3318 4.77e-18 85.1 COG3584@1|root,COG3584@2|Bacteria,1WKHT@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S 3D domain protein - - - - - - - - - - - - - k59_193038_1 428125.CLOLEP_00174 7.08e-07 58.9 COG5280@1|root,COG5412@1|root,COG5280@2|Bacteria,COG5412@2|Bacteria,1TPR1@1239|Firmicutes,25EEJ@186801|Clostridia,3WGX8@541000|Ruminococcaceae 186801|Clostridia S tail tape measure protein, TP901 - - - - - - - - - - - - PhageMin_Tail k59_665_1 1788447.A0A190WHJ9_9CIRC 3.49e-67 215.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_364970_1 1120950.KB892743_gene3089 1.41e-05 56.2 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups tuaC GO:0003674,GO:0003824,GO:0016740,GO:0016757 - ko:K16697 - - - - ko00000,ko01000,ko01003 - GT4 iYO844.BSU35590 Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 k59_364970_2 1354303.M917_2310 1.74e-35 125.0 2E8DW@1|root,332SB@2|Bacteria,1NH6J@1224|Proteobacteria,1SI26@1236|Gammaproteobacteria,3NPJH@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_182685_1 105154.Q9MBU3_9VIRU 1.1e-09 63.9 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_170532_1 438482.A4ZRC7_9CAUD 5.8e-25 108.0 4QNBD@10744|Podoviridae 10744|Podoviridae S outer membrane - - - - - - - - - - - - - k59_74288_1 1385658.U5KPZ6_9VIRU 2.63e-148 437.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_341323_3 1609634.A0A0C5ANA6_9VIRU 6.21e-15 79.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_110706_1 691965.D4P7L7_9CAUD 8.68e-192 570.0 4QB9J@10239|Viruses,4QXFE@35237|dsDNA viruses no RNA stage,4QS1Z@28883|Caudovirales,4QN8F@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_317316_1 1157708.KB907450_gene5441 2.13e-07 62.0 COG5434@1|root,COG5434@2|Bacteria,1RCW1@1224|Proteobacteria,2W4G2@28216|Betaproteobacteria 28216|Betaproteobacteria M Pectate lyase superfamily protein - - - - - - - - - - - - Pectate_lyase_3 k59_329370_1 1385658.U5KPZ6_9VIRU 4.03e-41 152.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_37696_1 105154.Q9MBU6_9VIRU 3.06e-18 84.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_37696_3 1165094.RINTHH_3920 1.62e-46 161.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_292986_1 156889.Mmc1_1716 3.54e-10 66.2 28NGF@1|root,2ZBII@2|Bacteria,1R9KY@1224|Proteobacteria,2U1P7@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_62409_2 1406780.U5PWL7_9CAUD 6.4e-07 53.5 4QAXA@10239|Viruses,4QYJI@35237|dsDNA viruses no RNA stage,4QQ1A@28883|Caudovirales,4QNU7@10744|Podoviridae 10744|Podoviridae S metallopeptidase activity - - - - - - - - - - - - - k59_13132_1 1123247.AUIJ01000002_gene2220 2.35e-32 125.0 28H75@1|root,2Z7JG@2|Bacteria,1MU3Y@1224|Proteobacteria,2TVB5@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage major capsid protein E - - - - - - - - - - - - Phage_cap_E k59_147295_3 438753.AZC_0839 7.82e-60 198.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,2U1P9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S DNA packaging protein gp2 gp2 - - - - - - - - - - - Terminase_6,Terminase_6C k59_281391_1 279238.Saro_2987 2.04e-177 505.0 2CYA9@1|root,32T3V@2|Bacteria,1RGRN@1224|Proteobacteria,2U90D@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_75332_7 1234888.K0A2J2_9VIRU 1.66e-44 159.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_111743_2 691966.D4P718_9CAUD 7.4e-134 395.0 4QB9S@10239|Viruses,4QUXK@35237|dsDNA viruses no RNA stage,4QPW1@28883|Caudovirales,4QM6J@10699|Siphoviridae 10699|Siphoviridae S Phage major capsid protein E - GO:0005575,GO:0019012,GO:0019028,GO:0019030,GO:0039620,GO:0044423 - - - - - - - - - - - k59_99632_1 145579.CAPSD_BPPHM 6.34e-66 228.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_13879_4 1429046.RR21198_2324 5.09e-11 74.7 COG0739@1|root,COG0741@1|root,COG0791@1|root,COG0739@2|Bacteria,COG0741@2|Bacteria,COG0791@2|Bacteria,2GP5E@201174|Actinobacteria,4FX1K@85025|Nocardiaceae 201174|Actinobacteria M NlpC/P60 family - - - - - - - - - - - - NLPC_P60,Peptidase_M23,SLT,SLT_2 k59_13879_9 999549.KI421514_gene16 4.14e-06 55.5 COG0863@1|root,COG0863@2|Bacteria,1R7RR@1224|Proteobacteria,2TS8Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase k59_13879_10 1120971.AUCA01000037_gene2882 5.59e-51 169.0 COG4725@1|root,COG4725@2|Bacteria,1TSJV@1239|Firmicutes 1239|Firmicutes KT Belongs to the MT-A70-like family - - - - - - - - - - - - MT-A70 k59_13879_11 1120998.AUFC01000019_gene320 4.13e-86 278.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,3WCCT@538999|Clostridiales incertae sedis 186801|Clostridia L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_63538_1 1094508.Tsac_2684 1.32e-24 106.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia,42FCZ@68295|Thermoanaerobacterales 186801|Clostridia L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k59_282809_3 105154.Q9MBU6_9VIRU 1.36e-190 549.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_111751_1 153496.JNAB01000014_gene794 1.56e-13 73.9 COG1351@1|root,COG1351@2|Bacteria,1MWY8@1224|Proteobacteria,2TTER@28211|Alphaproteobacteria,2JQGP@204441|Rhodospirillales 204441|Rhodospirillales F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant thyX - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 k59_111751_2 1347392.CCEZ01000060_gene3282 2.34e-08 52.8 2DVY7@1|root,32V0C@2|Bacteria,1VAXX@1239|Firmicutes,24P61@186801|Clostridia,36NXG@31979|Clostridiaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_209433_2 349106.PsycPRwf_1223 4.35e-14 75.9 COG3179@1|root,COG3179@2|Bacteria,1R71F@1224|Proteobacteria,1RZTY@1236|Gammaproteobacteria,3NJ60@468|Moraxellaceae 1236|Gammaproteobacteria S Chitinase class I - - - - - - - - - - - - Glyco_hydro_19,PG_binding_1 k59_197012_7 43759.JNWK01000062_gene3096 8.2e-42 157.0 COG4639@1|root,COG4639@2|Bacteria,2I9VQ@201174|Actinobacteria 201174|Actinobacteria S AAA domain pseT - 6.5.1.3 ko:K14680 - - - - ko00000,ko01000 - - - AAA_33,RNA_lig_T4_1 k59_26914_2 573413.Spirs_2497 4.49e-07 53.1 COG3740@1|root,COG3740@2|Bacteria,2JAN9@203691|Spirochaetes 203691|Spirochaetes S PFAM peptidase U35 phage prohead HK97 - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78 k59_184742_2 1618248.A0A0C5IB82_9CIRC 3.63e-18 90.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_39793_2 2880.D7FNN4 1.62e-06 54.3 COG0500@1|root,2S237@2759|Eukaryota 2759|Eukaryota Q methyltransferase activity - - - - - - - - - - - - Methyltransf_25,Methyltransf_31 k59_234509_1 1112212.JH584235_gene1720 3.77e-35 137.0 COG5545@1|root,COG5545@2|Bacteria 2|Bacteria - - - - - ko:K06919 - - - - ko00000 - - - D5_N,DUF3854,Pox_D5,PriCT_1,Prim-Pol,RepB_primase,VirE k59_14952_2 1196083.SALWKB12_0209 7.31e-06 55.5 COG2946@1|root,COG2946@2|Bacteria,1RDKM@1224|Proteobacteria,2VNHY@28216|Betaproteobacteria,2KQIU@206351|Neisseriales 206351|Neisseriales L Replication initiation factor - - - - - - - - - - - - Rep_trans k59_149427_1 573174.M4MBA3_9VIRU 8.81e-104 320.0 4QCHF@10239|Viruses,4QW57@35237|dsDNA viruses no RNA stage 10239|Viruses S PhoH-like protein - - - - - - - - - - - - - k59_270829_1 1234888.K0A2J2_9VIRU 2.93e-74 239.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_210718_1 1986029.Q9MBM8_9VIRU 2.5e-06 48.1 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_210718_2 1986029.Q9MBM7_9VIRU 1.85e-20 91.7 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_76697_1 665942.HMPREF1022_01557 8.8e-13 73.6 COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,42TVH@68525|delta/epsilon subdivisions,2WR7Q@28221|Deltaproteobacteria 28221|Deltaproteobacteria H C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_356186_1 1298858.AUEL01000029_gene80 2.26e-20 94.0 2C2IA@1|root,2ZW5P@2|Bacteria,1PB15@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_295548_1 1298858.AUEL01000029_gene80 6.45e-25 113.0 2C2IA@1|root,2ZW5P@2|Bacteria,1PB15@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_137300_1 1609634.A0A0C5AFV4_9VIRU 2.11e-67 223.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_137300_2 105154.Q9MBT9_9VIRU 9.25e-16 72.8 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_307799_1 1540221.JQNI01000002_gene518 9.98e-12 66.2 COG5323@1|root,COG5323@2|Bacteria 2|Bacteria M Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_307799_2 1380391.JIAS01000018_gene746 1.06e-11 67.0 28N1N@1|root,2ZB7Q@2|Bacteria,1R86T@1224|Proteobacteria,2U0A6@28211|Alphaproteobacteria,2JRMI@204441|Rhodospirillales 204441|Rhodospirillales H Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_1 k59_101276_1 716928.AJQT01000109_gene1217 2.29e-17 77.0 2FEUE@1|root,346TC@2|Bacteria,1MZPB@1224|Proteobacteria,2UC4Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_296594_2 348824.LPU83_1721 3.33e-54 190.0 COG0507@1|root,COG0507@2|Bacteria,1R1AT@1224|Proteobacteria,2U1ZX@28211|Alphaproteobacteria,4BAYZ@82115|Rhizobiaceae 28211|Alphaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - - - - - - - - - - Terminase_6 k59_357269_2 1211777.BN77_4169 1.07e-70 233.0 2C5GI@1|root,2Z8C1@2|Bacteria,1R8XM@1224|Proteobacteria,2TUME@28211|Alphaproteobacteria,4BJKS@82115|Rhizobiaceae 28211|Alphaproteobacteria S P22 coat protein - gene protein 5 - - - - - - - - - - - - P22_CoatProtein k59_53676_2 460265.Mnod_0605 7.6e-15 71.6 2ERZF@1|root,33JIJ@2|Bacteria,1NI6H@1224|Proteobacteria,2UM2F@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_333325_2 67267.JNXT01000054_gene2989 1.77e-19 93.6 2F1HE@1|root,33UHX@2|Bacteria,2IH41@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_102398_1 316058.RPB_0919 0.000496 49.3 COG4675@1|root,COG4675@2|Bacteria,1NX1F@1224|Proteobacteria,2US1X@28211|Alphaproteobacteria,3K496@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Phage Tail Collar Domain - - - - - - - - - - - - Collar k59_345314_2 1122963.AUHB01000017_gene1949 3.08e-161 473.0 COG0507@1|root,COG0507@2|Bacteria,1R1AT@1224|Proteobacteria,2U1ZX@28211|Alphaproteobacteria 28211|Alphaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - - - - - - - - - - Terminase_6 k59_41291_2 1416760.AYMS01000023_gene3347 5.21e-05 51.6 COG0463@1|root,COG0463@2|Bacteria,4NKU8@976|Bacteroidetes,1I0B4@117743|Flavobacteriia,47ITV@76831|Myroides 976|Bacteroidetes M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 k59_90364_1 580332.Slit_1922 4.46e-62 207.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,2VM59@28216|Betaproteobacteria 28216|Betaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_259952_2 234621.RER_25240 8.65e-18 81.3 2DYV8@1|root,32V63@2|Bacteria,2GRK5@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_235718_1 691965.D4P7D6_9CAUD 4.26e-67 230.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_235718_2 691965.D4P7D3_9CAUD 7.86e-167 483.0 4QAYV@10239|Viruses,4QUZ7@35237|dsDNA viruses no RNA stage,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - k59_381711_1 1609634.A0A0C5AFV4_9VIRU 9.72e-155 456.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_150900_1 314275.MADE_1014545 3.35e-11 75.9 COG4733@1|root,COG4733@2|Bacteria,1NCQ4@1224|Proteobacteria,1SEXE@1236|Gammaproteobacteria,46BS4@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF1983) - - - - - - - - - - - - DUF1983,DUF3672 k59_126776_14 1088868.CIN_02710 1.12e-05 55.1 COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2UIYJ@28211|Alphaproteobacteria,2JZ97@204441|Rhodospirillales 204441|Rhodospirillales M Glycosyltransferase family 9 (heptosyltransferase) - - - - - - - - - - - - Glyco_transf_9 k59_138688_1 521011.Mpal_1783 7.34e-07 60.8 COG3291@1|root,arCOG02559@1|root,arCOG02508@2157|Archaea,arCOG02510@2157|Archaea,arCOG02559@2157|Archaea 2157|Archaea P by modhmm - - - - - - - - - - - - CBM_6,NosD,PKD,SBBP k59_92135_1 742733.HMPREF9469_05020 1.5e-57 212.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,221IX@1506553|Lachnoclostridium 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_42910_2 1788439.A0A190WHD0_9CIRC 5.2e-23 103.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_103810_2 1636270.A0A0E3JPE6_9CAUD 2e-92 282.0 4QB55@10239|Viruses,4QSJ0@28883|Caudovirales,4QNGX@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_213824_2 1455626.W5ZKV0_9CIRC 2.49e-37 140.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_273860_2 1261131.lam_490 0.000435 52.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,2U1P9@28211|Alphaproteobacteria,4BDQ9@82115|Rhizobiaceae 28211|Alphaproteobacteria S DNA packaging protein gp2 gp2 - - - - - - - - - - - Terminase_6,Terminase_6C k59_31121_1 1051675.G0YQJ1_9CAUD 3.18e-50 171.0 4QGM6@10239|Viruses,4QYNV@35237|dsDNA viruses no RNA stage,4QRH4@28883|Caudovirales,4QP0P@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_31121_3 1230338.MOMA_06891 4.11e-30 118.0 COG5362@1|root,COG5362@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Terminase_6C k59_152561_1 1385658.U5KNR1_9VIRU 1.1e-24 102.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_55254_2 1556290.A0A0A0RL96_9CAUD 2.27e-67 226.0 4QGMJ@10239|Viruses,4QSYG@28883|Caudovirales,4QM5B@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_347036_2 1196028.ALEF01000043_gene488 3.09e-21 99.8 COG5377@1|root,COG5377@2|Bacteria,1TS2Y@1239|Firmicutes,4HAFK@91061|Bacilli,4C5GW@84406|Virgibacillus 91061|Bacilli L YqaJ-like viral recombinase domain yqaJ - - - - - - - - - - - YqaJ k59_201063_1 59925.EU91_1412 2.38e-44 154.0 COG0451@1|root,COG0451@2|Bacteria 2|Bacteria GM ADP-glyceromanno-heptose 6-epimerase activity - - 5.1.3.2,5.1.3.6 ko:K01784,ko:K08679 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R01385,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd k59_164751_1 1986029.Q9MBM3_9VIRU 1.87e-44 156.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_347044_1 1197951.I6RT10_9CAUD 3.65e-06 53.9 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales 28883|Caudovirales S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_310600_1 661367.LLO_3162 1.05e-33 129.0 COG1083@1|root,COG1083@2|Bacteria,1QACI@1224|Proteobacteria,1RR92@1236|Gammaproteobacteria,1JFI9@118969|Legionellales 118969|Legionellales M Cytidylyltransferase neuA GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.7.82 ko:K18431 ko00520,map00520 - R10182 RC00152 ko00000,ko00001,ko01000 - - - CTP_transf_3 k59_310600_3 4006.Lus10005076 4.56e-48 172.0 arCOG06245@1|root,2QSDP@2759|Eukaryota,37P8P@33090|Viridiplantae,3GAX4@35493|Streptophyta,4JHI1@91835|fabids 35493|Streptophyta S Alpha-1,4-glucan-protein synthase UDP-forming RGP2 GO:0000138,GO:0003674,GO:0003735,GO:0003824,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005774,GO:0005794,GO:0005795,GO:0005829,GO:0005840,GO:0005844,GO:0005975,GO:0005996,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0006950,GO:0006970,GO:0007275,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009225,GO:0009555,GO:0009628,GO:0009651,GO:0009832,GO:0009987,GO:0010035,GO:0010038,GO:0012505,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0016759,GO:0016760,GO:0016853,GO:0016866,GO:0019321,GO:0019322,GO:0019566,GO:0019567,GO:0022626,GO:0030312,GO:0031090,GO:0031984,GO:0031985,GO:0032501,GO:0032502,GO:0032991,GO:0033356,GO:0034641,GO:0035251,GO:0042221,GO:0042546,GO:0042788,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044431,GO:0044437,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046364,GO:0046483,GO:0046527,GO:0046686,GO:0048229,GO:0048856,GO:0050896,GO:0052691,GO:0055086,GO:0071554,GO:0071669,GO:0071704,GO:0071840,GO:0071944,GO:0098588,GO:0098791,GO:0098805,GO:1901135,GO:1901360,GO:1901576,GO:1990904 5.4.99.30 ko:K13379 ko00520,map00520 - R09009 RC02396 ko00000,ko00001,ko01000,ko01003 - GT75 - RGP k59_310600_5 745411.B3C1_06824 1.8e-21 96.3 COG1083@1|root,COG1083@2|Bacteria,1RHF3@1224|Proteobacteria,1RYI8@1236|Gammaproteobacteria,1JB6X@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Cytidylyltransferase - - - - - - - - - - - - CTP_transf_3 k59_300434_1 316274.Haur_1031 3.44e-40 142.0 COG4627@1|root,COG4627@2|Bacteria 2|Bacteria - - - - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - Glycos_transf_2,Methyltransf_11,Methyltransf_23 k59_105386_13 1410620.SHLA_4c002110 5.04e-39 140.0 COG0237@1|root,COG0237@2|Bacteria,1NEFS@1224|Proteobacteria,2UIWS@28211|Alphaproteobacteria,4BKKU@82115|Rhizobiaceae 28211|Alphaproteobacteria H dephospho-CoA kinase activity - - - - - - - - - - - - - k59_105386_31 652103.Rpdx1_2535 1.02e-06 60.5 2DQ9V@1|root,335IH@2|Bacteria 2|Bacteria - - - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - - k59_130257_2 1187851.A33M_1719 4.64e-21 90.9 COG3613@1|root,COG3613@2|Bacteria 2|Bacteria F nucleoside 2-deoxyribosyltransferase - - - - - - - - - - - - DUF1937 k59_19241_1 1379719.S5TMX6_9CIRC 4.73e-15 79.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_251265_1 1165094.RINTHH_3920 2.13e-25 106.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_81407_1 2003327.CAPSD_BPCHP 3.02e-32 130.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_336833_1 1609634.A0A0C5AFV4_9VIRU 6.11e-83 266.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_215798_1 351160.LRC544 1.38e-13 75.1 COG0438@1|root,arCOG01403@2157|Archaea,2Y8BE@28890|Euryarchaeota 28890|Euryarchaeota M PFAM Glycosyl transferase, group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k59_142078_1 335992.SAR11_0539 2e-27 118.0 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1R7DJ@1224|Proteobacteria,2VF2S@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - - - - - - - - - - CTP_transf_like,PfkB k59_215805_2 986075.CathTA2_2439 8.57e-60 196.0 COG0270@1|root,COG0270@2|Bacteria,1TPNE@1239|Firmicutes,4HHQR@91061|Bacilli 91061|Bacilli H C-5 cytosine-specific DNA methylase - - - - - - - - - - - - DNA_methylase k59_348827_1 1121935.AQXX01000123_gene247 2.39e-11 62.8 2AD08@1|root,312N7@2|Bacteria,1NDC4@1224|Proteobacteria,1SAPT@1236|Gammaproteobacteria,1XQHK@135619|Oceanospirillales 135619|Oceanospirillales S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_348827_3 1273125.Rrhod_2045 0.000585 46.6 COG5479@1|root,COG5479@2|Bacteria,2GNDB@201174|Actinobacteria,4FUE3@85025|Nocardiaceae 201174|Actinobacteria M Animal peptidoglycan recognition proteins homologous to Bacteriophage T3 lysozyme. csp - - - - - - - - - - - Amidase_2,LGFP k59_204516_2 1618254.A0A0C5IBG4_9CIRC 1.76e-91 278.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_374234_1 1408428.JNJP01000003_gene3493 4.88e-47 159.0 COG0270@1|root,COG0270@2|Bacteria 2|Bacteria L DNA (cytosine-5-)-methyltransferase activity - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_291069_2 158500.BV97_03967 6.53e-25 99.4 2AEIC@1|root,314DS@2|Bacteria,1NM35@1224|Proteobacteria,2UMPW@28211|Alphaproteobacteria,2K7PX@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - HK97-gp10_like k59_46590_1 471854.Dfer_5508 3.95e-10 66.6 COG0616@1|root,COG0616@2|Bacteria 2|Bacteria OU serine-type peptidase activity sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49,SDH_sah k59_302537_1 1304275.C41B8_05408 8.61e-71 223.0 2DVPY@1|root,33WQ8@2|Bacteria,1N9VQ@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_204526_1 572480.Arnit_2436 1.17e-09 55.5 COG3311@1|root,COG3311@2|Bacteria,1NGB9@1224|Proteobacteria 1224|Proteobacteria K Transcriptional regulator - - - ko:K07733 - - - - ko00000,ko03000 - - - Phage_AlpA k59_167791_1 1234888.K0A2J2_9VIRU 1.85e-97 306.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_291073_1 1380347.JNII01000006_gene1446 0.00074 49.3 COG1749@1|root,COG2372@1|root,COG5184@1|root,COG1749@2|Bacteria,COG2372@2|Bacteria,COG5184@2|Bacteria,2I2X3@201174|Actinobacteria,4EUDH@85013|Frankiales 201174|Actinobacteria N Bacterial Ig-like domain - - - - - - - - - - - - Big_5,DUF4082,Mo-co_dimer,fn3 k59_338806_3 1415780.JPOG01000001_gene1779 2.1e-11 61.2 2EB1Y@1|root,3352R@2|Bacteria,1NASI@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_204684_1 105422.BBPM01000048_gene1658 1.21e-11 69.7 COG3409@1|root,COG3409@2|Bacteria,2GR1Q@201174|Actinobacteria,2NKK2@228398|Streptacidiphilus 201174|Actinobacteria M N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2,PG_binding_1 k59_229767_1 1234888.K0A2J2_9VIRU 2.03e-67 221.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_46761_2 1230469.M5AAF3_9CAUD 1.29e-15 77.0 4QBHW@10239|Viruses,4QW8N@35237|dsDNA viruses no RNA stage,4QTT7@28883|Caudovirales,4QKR7@10699|Siphoviridae 10699|Siphoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_96423_1 105154.Q9MBU6_9VIRU 1.36e-53 184.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_96423_2 105154.Q9MBT9_9VIRU 3.51e-18 79.3 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_314201_2 237368.SCABRO_02766 1.67e-16 79.7 COG0279@1|root,COG0279@2|Bacteria,2IZQU@203682|Planctomycetes 203682|Planctomycetes G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate gmhA - 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 - - - SIS_2 k59_314201_3 926569.ANT_19990 2.03e-95 292.0 COG2605@1|root,COG2605@2|Bacteria,2G5TF@200795|Chloroflexi 200795|Chloroflexi S PFAM GHMP kinase - - 2.7.1.168 ko:K07031 ko00540,map00540 - R09770 RC00002,RC00078 ko00000,ko00001,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N k59_326855_1 1609634.A0A0C5AFV4_9VIRU 4.78e-94 293.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_71214_1 95619.PM1_0217670 1.64e-06 55.5 COG3355@1|root,COG3355@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - EIIA-man,HWE_HK,PAS_4,PRD,Sigma54_activat k59_351788_1 1122614.JHZF01000011_gene1718 1.69e-11 63.5 2C7JB@1|root,2ZXVG@2|Bacteria,1P7GB@1224|Proteobacteria,2UYPK@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_351788_2 1430331.EP10_10445 1.44e-24 98.2 COG3405@1|root,COG3405@2|Bacteria,1VBUA@1239|Firmicutes,4HMXV@91061|Bacilli 91061|Bacilli G Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - - - - - - - - - - - k59_351788_6 398525.KB900701_gene6144 1.79e-46 167.0 28PTM@1|root,2ZCEU@2|Bacteria,1R5DD@1224|Proteobacteria,2TVG7@28211|Alphaproteobacteria,3JU4C@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_351788_7 1524880.A0A076G697_9VIRU 3.66e-06 57.0 4QD1M@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_133596_1 95619.PM1_0224510 5.22e-07 62.8 COG2911@1|root,COG2931@1|root,COG2982@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG2982@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG2931 RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - DUF4214,DUF4347,He_PIG,HemolysinCabind,PA14,VWA_2 k59_375963_1 113355.CM001775_gene2373 3.89e-44 160.0 28PYV@1|root,2ZCIC@2|Bacteria,1GBG4@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - k59_145699_1 105154.Q9MBU6_9VIRU 1.53e-58 196.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_145699_2 1609634.A0A0C5ANA6_9VIRU 4.43e-12 66.6 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_169400_1 1609634.A0A0C5AFT2_9VIRU 3.17e-76 238.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_352015_1 929703.KE386491_gene3009 0.000301 48.1 COG1403@1|root,COG1403@2|Bacteria,4NJ0T@976|Bacteroidetes,47MEF@768503|Cytophagia 976|Bacteroidetes L HNH endonuclease - - - - - - - - - - - - HNH,HNH_5 k59_11358_1 1609634.A0A0C5AFV4_9VIRU 1.01e-170 497.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_242327_2 1297570.MESS4_510151 3.45e-50 176.0 2EFF2@1|root,3397X@2|Bacteria,1P2XD@1224|Proteobacteria,2UYX3@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_60464_1 596153.Alide_1641 1.29e-79 242.0 2EKAP@1|root,33E0Y@2|Bacteria,1NAAI@1224|Proteobacteria,2VZTN@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_242329_1 478749.BRYFOR_08517 2.35e-25 100.0 2ECB3@1|root,3369E@2|Bacteria,1VEV9@1239|Firmicutes,24R69@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_254640_1 313624.NSP_18530 3.27e-26 107.0 COG3914@1|root,COG4627@1|root,COG3914@2|Bacteria,COG4627@2|Bacteria,1GDK4@1117|Cyanobacteria,1HSCI@1161|Nostocales 1117|Cyanobacteria O Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 k59_387753_3 402881.Plav_0908 1.27e-19 89.4 2CK39@1|root,32SBG@2|Bacteria,1MZ6F@1224|Proteobacteria,2UBT5@28211|Alphaproteobacteria,1JP9N@119043|Rhodobiaceae 28211|Alphaproteobacteria S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 k59_145712_1 1234888.K0A2J2_9VIRU 1.22e-130 391.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_328032_2 742733.HMPREF9469_05037 3.98e-14 70.1 2BD7A@1|root,326VE@2|Bacteria,1USRB@1239|Firmicutes,25ASG@186801|Clostridia,223BG@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_231187_2 1089111.G8I7V8_9CAUD 3.33e-26 102.0 4QGDB@10239|Viruses,4QZHU@35237|dsDNA viruses no RNA stage,4QSG0@28883|Caudovirales,4QM88@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_231187_3 1111730.ATTM01000002_gene1130 2.46e-10 65.5 COG0270@1|root,COG0270@2|Bacteria,4NRFG@976|Bacteroidetes 976|Bacteroidetes L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_146195_1 1094466.KQS_11905 8.99e-06 52.8 COG5272@1|root,COG5295@1|root,COG5272@2|Bacteria,COG5295@2|Bacteria,4NHCC@976|Bacteroidetes,1I3GX@117743|Flavobacteriia,2NZZ3@237|Flavobacterium 976|Bacteroidetes UW tail collar domain protein - - - - - - - - - - - - Collagen k59_316325_8 688245.CtCNB1_1438 1.8e-63 205.0 28J67@1|root,2Z91Y@2|Bacteria,1R7RG@1224|Proteobacteria,2VRTM@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_194850_1 1385658.U5KPZ6_9VIRU 2.78e-159 465.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_194850_4 1165094.RINTHH_3920 7.94e-59 197.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_170341_1 691965.D4P7I3_9CAUD 8.98e-161 491.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_170341_4 665956.HMPREF1032_00640 1.19e-48 171.0 2A0KC@1|root,2ZGJK@2|Bacteria,1V2JS@1239|Firmicutes,24H6R@186801|Clostridia,3WNJK@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_97561_1 1379717.S5SY19_9CIRC 1.05e-70 227.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_133977_13 298654.FraEuI1c_6157 6.2e-08 61.2 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - - - - - - - - - - HTH_3,HTH_31 k59_207093_1 1618257.A0A0C5IBI9_9CIRC 3.71e-56 184.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_316378_2 1692255.A0A0K1RL52_9CIRC 4.96e-128 374.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_182895_7 889338.G3BLN0_9CAUD 5.51e-14 74.3 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QI6J@10662|Myoviridae 10662|Myoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_243805_1 1208323.B30_20593 3.58e-25 119.0 COG0553@1|root,COG0553@2|Bacteria,1MXQH@1224|Proteobacteria,2TR5V@28211|Alphaproteobacteria 28211|Alphaproteobacteria KL methylase - - - - - - - - - - - - AAA_34,Helicase_C_4 k59_280701_2 472175.EL18_01354 8.61e-07 53.5 COG0438@1|root,COG0438@2|Bacteria,1PJ7G@1224|Proteobacteria,2U2TC@28211|Alphaproteobacteria,43Q7F@69277|Phyllobacteriaceae 28211|Alphaproteobacteria M Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 k59_25167_6 1329516.JPST01000018_gene2629 2.46e-10 70.9 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli,27BA0@186824|Thermoactinomycetaceae 91061|Bacilli L DnaB-like helicase C terminal domain - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_25167_10 485913.Krac_6085 7.41e-27 104.0 2DSBU@1|root,33FEQ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_316973_2 367737.Abu_1642 1.78e-50 168.0 COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,42N1U@68525|delta/epsilon subdivisions,2YMVV@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria F GTP cyclohydrolase folE - 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - iIT341.HP0928 GTP_cyclohydroI k59_292682_2 1123060.JONP01000003_gene454 1.43e-05 53.9 COG5434@1|root,COG5434@2|Bacteria,1N611@1224|Proteobacteria,2UE6M@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Belongs to the glycosyl hydrolase 28 family - - - - - - - - - - - - Pectate_lyase_3 k59_49722_2 1540097.A0A0A0YPX0_9CAUD 1.5e-87 273.0 4QEG2@10239|Viruses,4QRJ9@28883|Caudovirales,4QP0R@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_341120_1 1150626.PHAMO_340052 7.22e-06 50.1 2CK39@1|root,32SBG@2|Bacteria,1Q39J@1224|Proteobacteria,2VA7Q@28211|Alphaproteobacteria,2JX2Y@204441|Rhodospirillales 204441|Rhodospirillales S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 k59_316975_1 1234888.K0A2J2_9VIRU 9.42e-31 124.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_37437_1 1110502.TMO_0043 1.02e-27 119.0 28IJ1@1|root,2Z8K0@2|Bacteria,1R5PC@1224|Proteobacteria,2V9I5@28211|Alphaproteobacteria,2JTUW@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_134519_1 34506.g5467 3.37e-05 49.7 2D8HQ@1|root,2TAAX@2759|Eukaryota,3AJ6W@33154|Opisthokonta 33154|Opisthokonta - - - - - - - - - - - - - - - k59_61963_1 1385658.U5KPZ6_9VIRU 1.65e-180 522.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_61963_6 1609634.A0A0C5AFT2_9VIRU 1.46e-29 117.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_219961_1 1432056.X781_8090 1.26e-34 132.0 COG4653@1|root,COG4653@2|Bacteria,1MYMH@1224|Proteobacteria,1RR5E@1236|Gammaproteobacteria,1Y809@135625|Pasteurellales 135625|Pasteurellales S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_75006_4 1118055.CAGU01000060_gene694 3.23e-47 174.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,22GQG@1570339|Peptoniphilaceae 186801|Clostridia L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_269234_1 1385658.U5KPZ6_9VIRU 1.66e-56 191.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_2016_2 1126411.I1TEL3_9CIRC 1.2e-45 163.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_147788_1 1034115.G1D5E8_9CAUD 1.6e-25 107.0 4QARC@10239|Viruses,4QV4E@35237|dsDNA viruses no RNA stage,4QPDS@28883|Caudovirales,4QKXX@10699|Siphoviridae 10699|Siphoviridae S RNase_H superfamily - - - - - - - - - - - - - k59_366271_1 1357275.AVEL02000151_gene1536 5.02e-31 122.0 COG0863@1|root,COG0863@2|Bacteria,1MY4G@1224|Proteobacteria,1RQHA@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.113,2.1.1.72 ko:K00571,ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_269235_1 1367847.JCM7686_2943 2.7e-28 104.0 2E4KF@1|root,32ZFE@2|Bacteria,1NCMR@1224|Proteobacteria,2UHT7@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_244736_1 755164.D6PSV9_9CAUD 1.04e-05 52.4 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QII1@10662|Myoviridae 10662|Myoviridae S N-methyltransferase activity - - - - - - - - - - - - - k59_354532_2 160488.PP_2269 1.29e-20 87.4 COG3023@1|root,COG3023@2|Bacteria,1N032@1224|Proteobacteria,1SA9C@1236|Gammaproteobacteria 1236|Gammaproteobacteria V N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2 k59_330246_1 1029823.AFIE01000007_gene1881 1.81e-50 182.0 COG0454@1|root,COG0553@1|root,COG0827@1|root,COG1040@1|root,COG4646@1|root,COG0456@2|Bacteria,COG0553@2|Bacteria,COG0827@2|Bacteria,COG1040@2|Bacteria,COG4646@2|Bacteria,1MXQH@1224|Proteobacteria,1T52I@1236|Gammaproteobacteria,3NTTI@468|Moraxellaceae 1236|Gammaproteobacteria L methylase - - - - - - - - - - - - - k59_305920_1 10689.H9C0B6_BPCPT 2.19e-05 53.5 4QAIJ@10239|Viruses,4QVZ9@35237|dsDNA viruses no RNA stage,4QPXI@28883|Caudovirales 28883|Caudovirales S C-5 cytosine-specific DNA methylase - - - - - - - - - - - - - k59_38301_4 269797.Mbar_A2853 4e-12 79.0 COG3291@1|root,COG4677@1|root,arCOG02495@2157|Archaea,arCOG02510@2157|Archaea 2157|Archaea O PFAM PKD domain containing protein pecE - 3.1.1.11 ko:K01051 ko00040,ko01100,map00040,map01100 M00081 R02362 RC00460,RC00461 ko00000,ko00001,ko00002,ko01000 - - - Beta_helix,CBM_6,NosD,PKD,Pectinesterase k59_220998_1 1208583.COMX_09536 1.68e-05 52.0 COG5352@1|root,COG5352@2|Bacteria,1RHI6@1224|Proteobacteria,2TS7F@28211|Alphaproteobacteria,2JU3J@204441|Rhodospirillales 204441|Rhodospirillales S GcrA cell cycle regulator - - - ko:K13583 ko04112,map04112 - - - ko00000,ko00001 - - - GcrA k59_160153_1 391009.Tmel_0506 8.94e-18 87.8 COG0535@1|root,COG0535@2|Bacteria 2|Bacteria I radical SAM domain protein - - - - - - - - - - - - DUF512,Fer4_12,Radical_SAM,SPASM k59_366346_1 498761.HM1_0137 2.32e-07 60.5 COG1470@1|root,COG3210@1|root,COG4733@1|root,COG4886@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,COG4886@2|Bacteria,COG5492@2|Bacteria 2|Bacteria N domain, Protein - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - Big_2,CHU_C,Flg_new,LRR_5,RCC1,SLH k59_123834_1 1184251.TCELL_0178 1.01e-14 76.3 COG1091@1|root,arCOG01367@2157|Archaea,2XPWF@28889|Crenarchaeota 28889|Crenarchaeota M DTDP-4-dehydrorhamnose reductase rfbD - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind k59_244854_3 536019.Mesop_6541 8.01e-09 61.6 COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,2TRM0@28211|Alphaproteobacteria,43H2E@69277|Phyllobacteriaceae 28211|Alphaproteobacteria GM GDP-mannose 4,6 dehydratase rmlB - 4.1.1.35 ko:K08678 ko00520,ko01100,map00520,map01100 M00361 R01384 RC00508 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd k59_13563_4 1385658.U5KNR1_9VIRU 4.52e-76 243.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_13563_5 145579.C_BPPHM 4.33e-13 66.6 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_100266_1 1408433.JHXV01000008_gene166 8.54e-71 221.0 COG0208@1|root,COG0208@2|Bacteria,4NG18@976|Bacteroidetes,1HXA5@117743|Flavobacteriia,2PAD3@246874|Cryomorphaceae 976|Bacteroidetes F Ribonucleotide reductase, small chain nrdB - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_sm k59_331518_1 227470.Q76YK5_9CAUD 5.21e-09 64.3 4QH12@10239|Viruses,4QV5P@35237|dsDNA viruses no RNA stage,4QT11@28883|Caudovirales,4QJ7M@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_88226_1 497964.CfE428DRAFT_3202 5.09e-36 143.0 COG1061@1|root,COG1061@2|Bacteria 2|Bacteria L Type III restriction enzyme res subunit - - - - - - - - - - - - Helicase_C,ResIII,UPF0547 k59_210090_1 1556290.A0A0A0RM32_9CAUD 2.8e-79 251.0 4QASV@10239|Viruses,4QQ4N@28883|Caudovirales,4QM00@10699|Siphoviridae 10699|Siphoviridae S DNA-dependent ATPase activity - - - - - - - - - - - - - k59_210090_4 224324.aq_1008 1.08e-178 561.0 COG0587@1|root,COG0587@2|Bacteria,2G3PZ@200783|Aquificae 200783|Aquificae L TIGRFAM DNA polymerase III, alpha subunit dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,Intein_splicing,LAGLIDADG_3,PHP,tRNA_anti-codon k59_294733_1 1123288.SOV_2c10440 9.21e-67 220.0 COG0553@1|root,COG0553@2|Bacteria,1TP2C@1239|Firmicutes,4H2V4@909932|Negativicutes 909932|Negativicutes KL DEAD-like helicases superfamily - - - - - - - - - - - - N6_N4_Mtase k59_294733_2 1120971.AUCA01000053_gene371 5.98e-71 222.0 COG0863@1|root,COG0863@2|Bacteria,1UZIN@1239|Firmicutes,4HU16@91061|Bacilli 91061|Bacilli L DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_76012_3 105154.Q9MBU3_9VIRU 0.00013 49.3 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_76012_4 2003327.CAPSD_BPCHP 4.72e-139 421.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_184393_1 1385658.U5KPZ6_9VIRU 4.81e-42 152.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_161325_1 1220601.L7TQW5_9CAUD 4.54e-08 62.8 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales 28883|Caudovirales S DNA-dependent RNA polymerase - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_161327_1 765910.MARPU_09550 1.06e-28 120.0 COG4653@1|root,COG4653@2|Bacteria,1MWMB@1224|Proteobacteria,1S4MJ@1236|Gammaproteobacteria,1X0RU@135613|Chromatiales 135613|Chromatiales S Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_294856_1 891968.Anamo_0662 1.65e-46 175.0 COG0587@1|root,COG0587@2|Bacteria,3T9YG@508458|Synergistetes 508458|Synergistetes L DNA polymerase III alpha subunit dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP k59_39321_1 1408444.JHYC01000015_gene2153 1.07e-68 225.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RMCS@1236|Gammaproteobacteria,1JFM6@118969|Legionellales 118969|Legionellales E Beta-eliminating lyase - - - - - - - - - - - - DegT_DnrJ_EryC1 k59_40495_1 1234888.K0A2J2_9VIRU 1.33e-90 285.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_285113_3 493475.GARC_4876 2.58e-39 136.0 2AD08@1|root,312N7@2|Bacteria,1NDC4@1224|Proteobacteria,1SAPT@1236|Gammaproteobacteria,467W0@72275|Alteromonadaceae 1236|Gammaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_53023_1 1126411.I1TEL3_9CIRC 1.32e-20 91.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_332659_1 1048834.TC41_1874 1.06e-25 112.0 COG1061@1|root,COG1061@2|Bacteria,1TQ62@1239|Firmicutes,4HAJ1@91061|Bacilli 91061|Bacilli L helicase - - - - - - - - - - - - Helicase_C,ResIII k59_296025_2 626418.bglu_1g12050 4.63e-42 145.0 COG3772@1|root,COG3772@2|Bacteria,1N0ZQ@1224|Proteobacteria,2VVDM@28216|Betaproteobacteria,1K8XQ@119060|Burkholderiaceae 28216|Betaproteobacteria S lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_285117_3 742733.HMPREF9469_05026 1.13e-22 93.2 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia,221N8@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_381071_3 1385658.U5KPZ6_9VIRU 8.94e-177 513.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_65380_1 1692250.A0A0K1RLR1_9CIRC 7.91e-50 172.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_65380_2 1692242.A0A0K1RKZ2_9CIRC 4.83e-58 194.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_77213_1 314345.SPV1_06324 7.1e-94 301.0 COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria 1224|Proteobacteria L Subunit R is required for both nuclease and ATPase activities, but not for modification - - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - DUF3387,HSDR_N,ResIII k59_4599_1 1618254.A0A0C5IBG4_9CIRC 1.37e-124 362.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_101748_1 439375.Oant_2314 5.46e-57 186.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2TU8N@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_113581_1 596152.DesU5LDRAFT_1457 2.25e-130 384.0 COG5362@1|root,COG5362@2|Bacteria,1PYY9@1224|Proteobacteria,435M3@68525|delta/epsilon subdivisions,2WZZT@28221|Deltaproteobacteria,2M981@213115|Desulfovibrionales 28221|Deltaproteobacteria S TIGRFAM Phage - - - - - - - - - - - - - k59_296042_1 627192.SLG_29120 7.53e-05 50.8 COG0507@1|root,COG0507@2|Bacteria,1MUTR@1224|Proteobacteria,2TSQQ@28211|Alphaproteobacteria,2K2VF@204457|Sphingomonadales 204457|Sphingomonadales L Conjugal transfer protein - - - - - - - - - - - - AAA_30,MobA_MobL k59_286667_1 160488.PP_2293 2.8e-86 271.0 COG5410@1|root,COG5410@2|Bacteria,1N0W2@1224|Proteobacteria,1S03G@1236|Gammaproteobacteria 1236|Gammaproteobacteria K chromosome segregation - - - - - - - - - - - - - k59_286667_2 1525715.IX54_09690 5.25e-16 77.8 COG3108@1|root,COG3108@2|Bacteria,1QDAN@1224|Proteobacteria,2TV1K@28211|Alphaproteobacteria,2PWHJ@265|Paracoccus 28211|Alphaproteobacteria S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_2,Peptidase_M15_3 k59_286667_3 490103.B0FIM4_BPE32 1.43e-26 101.0 4QBH7@10239|Viruses,4QWWF@35237|dsDNA viruses no RNA stage,4QQ8R@28883|Caudovirales 28883|Caudovirales S DNA ligase (NAD+) activity - - - - - - - - - - - - - k59_41844_1 856793.MICA_600 5.46e-27 106.0 COG0582@1|root,COG0582@2|Bacteria,1NWGS@1224|Proteobacteria,2TQWR@28211|Alphaproteobacteria,4BSWZ@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria L Phage integrase family rci - - - - - - - - - - - Phage_integrase k59_357676_2 999423.HMPREF9161_01357 6.73e-102 309.0 COG1089@1|root,COG1089@2|Bacteria,1TQ9T@1239|Firmicutes,4H2Q3@909932|Negativicutes 909932|Negativicutes M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose gmd - 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd k59_286670_1 1504822.CCNO01000015_gene594 9.71e-131 398.0 COG0553@1|root,COG0863@1|root,COG0553@2|Bacteria,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_54128_1 1385658.U5KPZ6_9VIRU 6.29e-30 119.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_333816_1 745277.GRAQ_00893 7.04e-05 44.7 COG3108@1|root,COG3108@2|Bacteria 2|Bacteria S Peptidase M15 Z012_12330 - - ko:K02395,ko:K03791,ko:K17733 - - - - ko00000,ko01000,ko01002,ko01011,ko02035 - GH19 - Peptidase_M15_3,Peptidase_M15_4 k59_321844_1 1123020.AUIE01000007_gene3229 0.000301 45.8 2CJWY@1|root,31CWF@2|Bacteria,1RKEF@1224|Proteobacteria,1S75P@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_321844_2 97139.C824_05152 4.77e-25 110.0 COG0535@1|root,COG0535@2|Bacteria,1V348@1239|Firmicutes,24GVU@186801|Clostridia 186801|Clostridia C Radical SAM superfamily - - - - - - - - - - - - Fer4_12,Radical_SAM,SPASM k59_321844_3 1357399.HMPREF2087_00488 1.66e-09 63.9 COG2520@1|root,COG2520@2|Bacteria,1N28Y@1224|Proteobacteria,43BVD@68525|delta/epsilon subdivisions 1224|Proteobacteria J Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 k59_321919_2 1477404.A0A023NI07_9CAUD 6.13e-26 107.0 4QF3C@10239|Viruses,4QWIA@35237|dsDNA viruses no RNA stage,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_91098_1 314254.OA2633_05141 0.000572 46.6 COG0500@1|root,COG2226@2|Bacteria,1R3QX@1224|Proteobacteria,2U5WJ@28211|Alphaproteobacteria,43ZAT@69657|Hyphomonadaceae 28211|Alphaproteobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11,Methyltransf_23 k59_30327_1 485918.Cpin_4755 0.000232 51.6 COG3420@1|root,COG3420@2|Bacteria,4P11U@976|Bacteroidetes 976|Bacteroidetes P Periplasmic copper-binding protein (NosD) - - - - - - - - - - - - Beta_helix k59_176092_1 1379719.S5TMX6_9CIRC 2.17e-19 88.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_345956_1 1294142.CINTURNW_4063 4.17e-11 72.8 COG1216@1|root,COG1216@2|Bacteria,1V06G@1239|Firmicutes,247WU@186801|Clostridia,36GAS@31979|Clostridiaceae 186801|Clostridia H glycosyl transferase family - - - - - - - - - - - - Glycos_transf_2,Methyltransf_23 k59_41985_6 1229760.K4IBY8_9CAUD 1.63e-26 107.0 4QBFR@10239|Viruses,4QV1E@35237|dsDNA viruses no RNA stage,4QPRX@28883|Caudovirales,4QICS@10662|Myoviridae 10662|Myoviridae S ERF superfamily - - - - - - - - - - - - - k59_224815_1 1123075.AUDP01000023_gene2902 2e-07 55.8 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,248P4@186801|Clostridia,3WNTM@541000|Ruminococcaceae 186801|Clostridia L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity - - - - - - - - - - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k59_369744_4 105154.Q9MBU3_9VIRU 7.79e-17 82.4 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_369744_5 1609634.A0A0C5AFV4_9VIRU 3.22e-223 634.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_140704_1 1411685.U062_00586 4.69e-40 145.0 COG0433@1|root,COG0433@2|Bacteria,1QTVP@1224|Proteobacteria,1T1IQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_323356_1 1123487.KB892865_gene1388 5.77e-28 121.0 COG3378@1|root,COG3378@2|Bacteria 2|Bacteria KL Phage plasmid primase P4 family - - - ko:K06919 - - - - ko00000 - - - PriCT_2,Prim-Pol k59_43333_1 1235835.C814_00341 1.15e-08 56.6 COG5377@1|root,COG5377@2|Bacteria,1TS2Y@1239|Firmicutes,249SB@186801|Clostridia,3WKYR@541000|Ruminococcaceae 186801|Clostridia L YqaJ viral recombinase family - - - - - - - - - - - - YqaJ k59_43333_20 679935.Alfi_2703 2.89e-90 301.0 28IFC@1|root,2Z8H3@2|Bacteria,4NJUZ@976|Bacteroidetes,2FPHP@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_43333_21 679935.Alfi_2709 1e-133 412.0 COG4373@1|root,COG4373@2|Bacteria,4NI4T@976|Bacteroidetes,2FNH0@200643|Bacteroidia 976|Bacteroidetes S Mu-like prophage FluMu protein gp28 - - - - - - - - - - - - - k59_43333_23 1192759.AKIB01000023_gene2907 2.98e-66 254.0 COG0553@1|root,COG0827@1|root,COG3087@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG3087@2|Bacteria,COG4646@2|Bacteria,1PGZG@1224|Proteobacteria,2TVEU@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DEAD-like helicases superfamily - - - - - - - - - - - - Helicase_C,N6_Mtase,ResIII,SNF2_N k59_80058_1 1429046.RR21198_4856 3.52e-11 64.3 2C9JF@1|root,32RPD@2|Bacteria,2GS69@201174|Actinobacteria,4G5U3@85025|Nocardiaceae 201174|Actinobacteria S ERF superfamily - - - - - - - - - - - - ERF k59_201495_1 1394178.AWOO02000044_gene4503 5.42e-31 123.0 COG0639@1|root,COG0639@2|Bacteria,2I6ZG@201174|Actinobacteria 201174|Actinobacteria T Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP - - - - - - - - - - - - Metallophos k59_7218_1 1385658.U5KPZ6_9VIRU 1.98e-50 177.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_250060_1 518766.Rmar_0924 1.48e-14 67.4 COG2331@1|root,COG2331@2|Bacteria,4P8SQ@976|Bacteroidetes,1FJMJ@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Putative regulatory protein - - - - - - - - - - - - Zn-ribbon_8 k59_80064_2 105154.Q9MBU0_9VIRU 1.19e-54 188.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_237605_1 28229.ND2E_3441 7.59e-35 127.0 COG1196@1|root,COG1196@2|Bacteria,1NK8W@1224|Proteobacteria,1SGJD@1236|Gammaproteobacteria 1236|Gammaproteobacteria D DNA N-6-adenine-methyltransferase (Dam) - - - - - - - - - - - - Dam k59_116086_1 203119.Cthe_2488 1.38e-15 82.4 COG5281@1|root,COG5281@2|Bacteria,1TPWF@1239|Firmicutes,24A8R@186801|Clostridia,3WN6S@541000|Ruminococcaceae 186801|Clostridia S tape measure - - - - - - - - - - - - - k59_31678_1 1175654.A0A0S0N897_9CAUD 3.76e-150 445.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_44830_4 7217.FBpp0121063 1.49e-08 63.2 COG0749@1|root,KOG0950@2759|Eukaryota,38BKB@33154|Opisthokonta,3BATG@33208|Metazoa,3CT13@33213|Bilateria,41U03@6656|Arthropoda,3SI6X@50557|Insecta,44XF3@7147|Diptera,45TCH@7214|Drosophilidae 33208|Metazoa A DNA-directed DNA polymerase activity. It is involved in the biological process described with POLQ GO:0000018,GO:0000724,GO:0000725,GO:0000726,GO:0002200,GO:0002376,GO:0002377,GO:0002440,GO:0002520,GO:0002566,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003684,GO:0003824,GO:0003887,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006282,GO:0006284,GO:0006289,GO:0006302,GO:0006303,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007275,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010569,GO:0010605,GO:0016043,GO:0016445,GO:0016446,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0016829,GO:0016835,GO:0016887,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031324,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0036297,GO:0042623,GO:0042802,GO:0043142,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045738,GO:0045910,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051259,GO:0051260,GO:0051575,GO:0051716,GO:0060255,GO:0065003,GO:0065007,GO:0070013,GO:0071704,GO:0071840,GO:0071897,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097681,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2000042,GO:2000779,GO:2000780,GO:2001020,GO:2001021 2.7.7.7 ko:K02349 - - - - ko00000,ko01000,ko03400 - - - DEAD,DNA_pol_A,Helicase_C k59_105492_1 935848.JAEN01000007_gene2923 1.65e-44 162.0 COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,2PUVK@265|Paracoccus 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_179133_1 323097.Nham_0587 2.32e-05 52.8 COG1520@1|root,COG1520@2|Bacteria 2|Bacteria S amino acid activation for nonribosomal peptide biosynthetic process - - - - - - - - - - - - FG-GAP_2,PQQ_2 k59_215888_1 1321782.HMPREF1986_02268 1.09e-29 114.0 COG4653@1|root,COG4653@2|Bacteria,1UZMZ@1239|Firmicutes,24BQJ@186801|Clostridia 186801|Clostridia S Phage capsid family - - - - - - - - - - - - CarboxypepD_reg,Phage_capsid k59_81507_1 1986029.Q9MBM6_9VIRU 1.78e-21 91.3 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_300731_2 1215114.BBIU01000011_gene1684 8.92e-29 108.0 2DSAB@1|root,33F8C@2|Bacteria 2|Bacteria S Protein of unknown function (DUF3168) - - - - - - - - - - - - DUF3168 k59_44831_1 1537917.JU82_06570 3.26e-47 158.0 2CGG9@1|root,2ZVSJ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_275718_1 908937.Prede_1741 1.33e-09 66.2 COG0210@1|root,COG0210@2|Bacteria,4NDWN@976|Bacteroidetes,2FNIM@200643|Bacteroidia 976|Bacteroidetes L DNA helicase pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k59_8405_2 1149133.ppKF707_0757 2.27e-21 94.4 COG0237@1|root,COG0237@2|Bacteria,1P8TB@1224|Proteobacteria,1TC1Y@1236|Gammaproteobacteria,1YJNV@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria H dephospho-CoA kinase activity - - - - - - - - - - - - - k59_8405_4 1094553.MCS_01038 6.84e-09 66.6 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,48T5Y@772|Bartonellaceae 28211|Alphaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_312320_1 1123236.KB899385_gene2505 2.42e-14 81.6 2E57E@1|root,32ZZZ@2|Bacteria,1NATW@1224|Proteobacteria,1SHJV@1236|Gammaproteobacteria,46973@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_312320_4 1636271.A0A0E3M3Z6_9CAUD 1.98e-32 121.0 4QFVK@10239|Viruses,4QSUR@28883|Caudovirales,4QM8N@10699|Siphoviridae 10699|Siphoviridae S transferase activity - - - - - - - - - - - - - k59_57033_1 1439940.BAY1663_02360 9.89e-18 88.2 28JTG@1|root,2Z9IR@2|Bacteria,1PCXZ@1224|Proteobacteria,1SIJB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_275877_2 747763.D7NW53_9CAUD 5.53e-13 70.5 4QBD3@10239|Viruses,4QXFU@35237|dsDNA viruses no RNA stage,4QQ7Z@28883|Caudovirales,4QM04@10699|Siphoviridae 10699|Siphoviridae S viral capsid - - - - - - - - - - - - - k59_8566_2 7217.FBpp0113698 4.74e-14 75.9 2CMNT@1|root,2QR3D@2759|Eukaryota,39UHX@33154|Opisthokonta,3B9U3@33208|Metazoa,3D2YM@33213|Bilateria,4201I@6656|Arthropoda,3SMSN@50557|Insecta,44XAB@7147|Diptera,45W30@7214|Drosophilidae 33208|Metazoa G N-acetylmuramoyl-L-alanine amidase activity. It is involved in the biological process described with peptidoglycan catabolic process - GO:0000270,GO:0002376,GO:0003674,GO:0003824,GO:0005488,GO:0005539,GO:0005575,GO:0005576,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006950,GO:0006952,GO:0006955,GO:0008150,GO:0008152,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0016787,GO:0016810,GO:0016811,GO:0030203,GO:0042834,GO:0043170,GO:0045087,GO:0050896,GO:0061783,GO:0071704,GO:0097367,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K01446 - - R04112 RC00064,RC00141 ko00000 - - - Amidase_2 k59_20887_1 318586.Pden_3767 2.45e-20 100.0 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,2TVGJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_313932_1 1437882.AZRU01000008_gene2926 8.37e-05 46.2 2DM98@1|root,327XW@2|Bacteria,1RH12@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_313932_2 558173.CDOO_04995 0.000521 42.4 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - GO:0002791,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0032879,GO:0032880,GO:0050708,GO:0050789,GO:0050794,GO:0051046,GO:0051049,GO:0051223,GO:0062012,GO:0065007,GO:0070201,GO:0080090,GO:0090087,GO:0097159,GO:1901363,GO:1903530 - - - - - - - - - - HTH_19,HTH_3,HTH_31,HTH_37 k59_277104_2 1234888.K0A2J2_9VIRU 1.37e-145 432.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_204449_2 1609634.A0A0C5AFV4_9VIRU 8.82e-109 333.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_240530_1 1609634.A0A0C5AFV4_9VIRU 9.96e-57 193.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_143820_2 626887.J057_01665 7.38e-25 105.0 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,1RR0M@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_338531_1 1692256.A0A0K1RL85_9CIRC 3.9e-06 51.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_180940_1 472759.Nhal_2030 0.000769 51.6 COG2340@1|root,COG2340@2|Bacteria,1MZ84@1224|Proteobacteria,1SFYU@1236|Gammaproteobacteria,1X0NT@135613|Chromatiales 135613|Chromatiales S Cysteine-rich secretory protein family - - - - - - - - - - - - CAP,PKD k59_96351_2 888055.HMPREF9015_01067 8.07e-07 57.8 COG3935@1|root,COG3935@2|Bacteria,37ANW@32066|Fusobacteria 32066|Fusobacteria L Helix-turn-helix domain - - - - - - - - - - - - HTH_36 k59_83314_1 693444.D782_3233 1.6e-41 144.0 COG1475@1|root,COG1475@2|Bacteria,1R5VN@1224|Proteobacteria,1RZ7C@1236|Gammaproteobacteria 1236|Gammaproteobacteria K ParB-like nuclease domain ybdM - - - - - - - - - - - ParBc k59_204636_1 1121861.KB899916_gene1673 7.5e-09 53.5 2BRUV@1|root,32KV2@2|Bacteria,1NNHF@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_277312_1 1382306.JNIM01000001_gene819 2.3e-05 50.4 COG0863@1|root,COG0863@2|Bacteria,2G9TE@200795|Chloroflexi 200795|Chloroflexi L DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_361821_3 521011.Mpal_2185 1.72e-14 77.4 COG0463@1|root,arCOG01381@2157|Archaea 2157|Archaea M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 k59_84992_1 375286.mma_2205 4.46e-90 294.0 COG2268@1|root,COG2268@2|Bacteria,1NT13@1224|Proteobacteria 1224|Proteobacteria S Band 7 protein - - - - - - - - - - - - - k59_266157_1 66269.NL54_03215 4.96e-20 91.3 COG4227@1|root,COG4227@2|Bacteria,1MU8I@1224|Proteobacteria,1RNU7@1236|Gammaproteobacteria,3W0HI@53335|Pantoea 1236|Gammaproteobacteria L Domain of unknown function (DUF1738) traC - - - - - - - - - - - DUF1738,Toprim_4 k59_340197_4 1341151.ASZU01000008_gene1531 1.13e-28 125.0 COG1783@1|root,COG1783@2|Bacteria,1VK0H@1239|Firmicutes,4HQ2H@91061|Bacilli 91061|Bacilli S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_22470_1 48698.ENSPFOP00000000643 2.57e-11 68.2 COG0553@1|root,KOG1000@2759|Eukaryota,38C05@33154|Opisthokonta,3BE0M@33208|Metazoa,3CT9F@33213|Bilateria,4833X@7711|Chordata,4986G@7742|Vertebrata,49SS9@7898|Actinopterygii 33208|Metazoa B regulator of chromatin, subfamily a-like SMARCAL1 GO:0000278,GO:0000723,GO:0000724,GO:0000725,GO:0000726,GO:0000733,GO:0001325,GO:0001501,GO:0001525,GO:0001568,GO:0001944,GO:0002376,GO:0002520,GO:0003674,GO:0003676,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005700,GO:0005705,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006302,GO:0006310,GO:0006355,GO:0006357,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007049,GO:0007275,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009378,GO:0009653,GO:0009790,GO:0009888,GO:0009889,GO:0009987,GO:0010171,GO:0010172,GO:0010468,GO:0010556,GO:0010709,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030097,GO:0030491,GO:0031297,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0032200,GO:0032392,GO:0032501,GO:0032502,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0035239,GO:0035295,GO:0035861,GO:0036292,GO:0036310,GO:0040007,GO:0042592,GO:0042623,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044464,GO:0045002,GO:0045003,GO:0045005,GO:0046483,GO:0048513,GO:0048514,GO:0048534,GO:0048589,GO:0048598,GO:0048646,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051216,GO:0051252,GO:0051276,GO:0051716,GO:0060249,GO:0060255,GO:0061306,GO:0061448,GO:0065007,GO:0065008,GO:0070013,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0072358,GO:0072359,GO:0080090,GO:0090304,GO:0090656,GO:0090734,GO:0090737,GO:0097159,GO:0097617,GO:0098687,GO:0140097,GO:1901360,GO:1901363,GO:1901576,GO:1903506,GO:1990163,GO:2000112,GO:2001141 3.6.4.12 ko:K14440 - - - - ko00000,ko01000,ko03036 - - - HARP,Helicase_C,SNF2_N k59_120417_1 10761.Q716H0_BPSFV 8.7e-32 127.0 4QBD3@10239|Viruses,4QXFU@35237|dsDNA viruses no RNA stage,4QQ7Z@28883|Caudovirales,4QNJ0@10744|Podoviridae 10744|Podoviridae S P22 coat protein - gene protein 5 - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0009987,GO:0016032,GO:0016043,GO:0019012,GO:0019028,GO:0019030,GO:0019058,GO:0019068,GO:0019069,GO:0019075,GO:0022607,GO:0039620,GO:0042802,GO:0042803,GO:0044085,GO:0044403,GO:0044419,GO:0044423,GO:0046729,GO:0046797,GO:0046983,GO:0051704,GO:0071840 - - - - - - - - - - - k59_254555_2 1692253.A0A0K1RLM4_9CIRC 2.48e-16 85.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_84994_2 996306.SSUR61_0556 2.28e-54 184.0 COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,4HBD5@91061|Bacilli,1WSZP@1307|Streptococcus suis 91061|Bacilli T PhoH-like protein phoH - - ko:K06217 - - - - ko00000 - - - PhoH k59_60379_1 105154.Q9MBU3_9VIRU 1.79e-13 72.0 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_145629_1 1609634.A0A0C5AFT2_9VIRU 3.79e-79 250.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_145629_4 1609634.A0A0C5AFV4_9VIRU 1.48e-191 553.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_327969_2 243159.AFE_1215 1.81e-25 115.0 COG0675@1|root,COG0675@2|Bacteria,1MUU0@1224|Proteobacteria,1RS1J@1236|Gammaproteobacteria,2NBUT@225057|Acidithiobacillales 225057|Acidithiobacillales L Probable transposase - - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon k59_48134_1 1476390.A0A060RFG0_9CAUD 6.28e-35 137.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_278647_1 1449069.JMLO01000006_gene992 0.000117 45.1 COG1403@1|root,COG1403@2|Bacteria,2GW76@201174|Actinobacteria,4G4XJ@85025|Nocardiaceae 201174|Actinobacteria V HNH nucleases - - - - - - - - - - - - HNH k59_11282_1 1519464.HY22_07965 2.85e-35 137.0 COG0209@1|root,COG0209@2|Bacteria 2|Bacteria F ribonucleoside-diphosphate reductase activity rtpR - 1.1.98.6,1.17.4.1 ko:K00525,ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024,R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,LAGLIDADG_3,Ribonuc_red_lgC k59_190215_1 991905.SL003B_4036 2.2e-23 104.0 COG5449@1|root,COG5449@2|Bacteria,1MXK2@1224|Proteobacteria,2TTWS@28211|Alphaproteobacteria 1224|Proteobacteria S Conserved protein - - - - - - - - - - - - DUF2163,Phage_BR0599 k59_169337_1 1122218.KB893668_gene2912 0.000585 52.8 COG1511@1|root,COG5283@1|root,COG1511@2|Bacteria,COG5283@2|Bacteria,1PGM4@1224|Proteobacteria,2V9RM@28211|Alphaproteobacteria,1JYSQ@119045|Methylobacteriaceae 28211|Alphaproteobacteria S domain protein - - - - - - - - - - - - - k59_254563_1 113355.CM001775_gene2373 3.5e-21 95.9 28PYV@1|root,2ZCIC@2|Bacteria,1GBG4@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - k59_206135_1 1123502.AQXD01000001_gene885 0.000123 55.1 COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,1RNWD@1236|Gammaproteobacteria,1X3HM@135614|Xanthomonadales 135614|Xanthomonadales O Molecular chaperone. Has ATPase activity htpG - - ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 - - - ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 - - - HATPase_c,HATPase_c_3,HSP90 k59_60871_2 765698.Mesci_3819 5.98e-40 141.0 28NGF@1|root,2ZBII@2|Bacteria,1R9KY@1224|Proteobacteria,2U1P7@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_85195_2 1128912.GMES_4611 1.06e-32 119.0 2AD08@1|root,312N7@2|Bacteria,1NDC4@1224|Proteobacteria,1SAPT@1236|Gammaproteobacteria,467W0@72275|Alteromonadaceae 1236|Gammaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_243125_1 1385658.U5KPZ6_9VIRU 5.43e-31 122.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_121623_1 1385658.U5KPZ6_9VIRU 1.25e-88 279.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_85199_1 484770.UFO1_0717 3.01e-09 65.1 COG0714@1|root,COG0714@2|Bacteria,1U8NZ@1239|Firmicutes,4H21E@909932|Negativicutes 909932|Negativicutes S associated with various cellular activities - - - - - - - - - - - - AAA,AAA_5 k59_364568_2 1609634.A0A0C5ANA6_9VIRU 2.67e-41 147.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_364568_5 1609634.A0A0C5AFT2_9VIRU 2.24e-148 427.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_364568_7 1609634.A0A0C5AFV4_9VIRU 1.23e-116 352.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_291725_1 1788444.A0A190WHA5_9CIRC 6.68e-20 92.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_328170_3 1112216.JH594425_gene1957 2.6e-30 118.0 2BHYZ@1|root,32C3A@2|Bacteria,1PZ9T@1224|Proteobacteria,2V3ER@28211|Alphaproteobacteria,2KB8W@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - k59_267335_2 870967.VIS19158_08213 4.21e-92 282.0 COG0433@1|root,COG0433@2|Bacteria,1QTVP@1224|Proteobacteria,1T1IQ@1236|Gammaproteobacteria,1XY9N@135623|Vibrionales 135623|Vibrionales S Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_206722_1 1122194.AUHU01000013_gene665 1.82e-47 164.0 COG4128@1|root,COG4128@2|Bacteria,1REHG@1224|Proteobacteria,1S491@1236|Gammaproteobacteria,46BRE@72275|Alteromonadaceae 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_340334_2 1526550.A0A088F868_9VIRU 6.15e-20 84.3 4QD1J@10239|Viruses 10239|Viruses S Protein of unknown function (DUF1364) - - - - - - - - - - - - - k59_133789_1 91604.ID47_02960 6.64e-33 125.0 28HS3@1|root,2Z7ZE@2|Bacteria,1QH9A@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_316058_3 1437448.AZRT01000014_gene1731 3e-08 54.3 2ERGC@1|root,33J1W@2|Bacteria,1NN9S@1224|Proteobacteria,2UKDV@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_316058_4 1380387.JADM01000008_gene942 3.87e-219 613.0 COG1783@1|root,COG1783@2|Bacteria,1MWGP@1224|Proteobacteria,1RMTH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_207135_2 1500257.JQNM01000006_gene1762 2.63e-06 50.8 COG0827@1|root,COG1040@1|root,COG3170@1|root,COG3773@1|root,COG0827@2|Bacteria,COG1040@2|Bacteria,COG3170@2|Bacteria,COG3773@2|Bacteria,1QV41@1224|Proteobacteria 1224|Proteobacteria F acetyltransferase - - - - - - - - - - - - - k59_364871_2 1788455.A0A190WHF5_9CIRC 3.23e-60 199.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_158493_1 1120792.JAFV01000001_gene3541 6.11e-06 52.8 COG4653@1|root,COG4653@2|Bacteria,1MWMB@1224|Proteobacteria,2TUJN@28211|Alphaproteobacteria,36YZI@31993|Methylocystaceae 28211|Alphaproteobacteria S Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_158493_4 225937.HP15_1959 3.28e-19 89.0 2EFFY@1|root,3398P@2|Bacteria,1NCVZ@1224|Proteobacteria,1SFQ2@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Prophage minor tail protein Z (GPZ) - - - - - - - - - - - - Minor_tail_Z k59_340585_2 445961.IW15_10100 2.3e-17 97.4 COG3941@1|root,COG3941@2|Bacteria,4NPQ5@976|Bacteroidetes 976|Bacteroidetes S tape measure - - - - - - - - - - - - - k59_255557_3 1692256.A0A0K1RL85_9CIRC 1.13e-76 243.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_352942_1 173824.Q9HH54_9CAUD 1.79e-10 69.3 4QH67@10239|Viruses,4QXEE@35237|dsDNA viruses no RNA stage,4QTBT@28883|Caudovirales,4QMA5@10699|Siphoviridae 10699|Siphoviridae S Terminase-like family - - - - - - - - - - - - - k59_243329_1 2003327.CAPSD_BPCHP 7.12e-50 176.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_243329_3 1385658.U5KNR1_9VIRU 1.89e-28 116.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_195004_1 1788447.A0A190WHJ9_9CIRC 7.02e-11 68.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_195004_2 1618256.A0A0C5I294_9CIRC 1.3e-22 97.8 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_195004_5 291603.MREP_FBNY1 8.36e-18 86.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_134616_18 1235790.C805_00500 2.16e-24 107.0 COG1044@1|root,COG1044@2|Bacteria,1TP7W@1239|Firmicutes,24HJW@186801|Clostridia 186801|Clostridia M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD - 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hexapep,Hexapep_2,LpxD k59_134616_19 439481.Aboo_0239 1.57e-19 89.7 COG2120@1|root,arCOG03460@2157|Archaea,2XVSC@28890|Euryarchaeota 28890|Euryarchaeota S PFAM LmbE family protein - - - - - - - - - - - - PIG-L k59_134616_20 866895.HBHAL_2436 4.15e-18 90.5 COG0438@1|root,COG2520@1|root,COG0438@2|Bacteria,COG2520@2|Bacteria,1U9Z2@1239|Firmicutes,4HEVV@91061|Bacilli 91061|Bacilli M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1,Glycos_transf_2,Methyltransf_21 k59_134616_21 796606.BMMGA3_10640 5.07e-07 56.6 COG2120@1|root,COG2120@2|Bacteria,1TV10@1239|Firmicutes,4HFJQ@91061|Bacilli,1ZAZI@1386|Bacillus 91061|Bacilli S proteins, LmbE homologs ypjG - - ko:K01463 - - - - ko00000,ko01000 - - - PIG-L k59_134616_24 266835.14027385 8.67e-135 402.0 COG5362@1|root,COG5362@2|Bacteria,1R90H@1224|Proteobacteria,2U236@28211|Alphaproteobacteria,43Q6Z@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_134616_26 1217710.F969_00003 3.04e-06 57.0 COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,1RPM4@1236|Gammaproteobacteria,3NPF7@468|Moraxellaceae 1236|Gammaproteobacteria L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_37583_1 444875.E3SMF7_9CAUD 4.35e-12 74.3 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNBD@10744|Podoviridae 10744|Podoviridae S outer membrane - - - - - - - - - - - - - k59_365434_4 243090.RB2479 4.07e-07 53.1 COG2242@1|root,COG2242@2|Bacteria 2|Bacteria H protein methyltransferase activity - - - - - - - - - - - - Methyltransf_21 k59_377931_3 478749.BRYFOR_08514 1.1e-38 133.0 2ARVA@1|root,31H70@2|Bacteria,1V7JT@1239|Firmicutes,24JPE@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - HK97-gp10_like k59_377931_4 691965.D4P7E6_9CAUD 3.39e-122 431.0 4QAK6@10239|Viruses,4R01K@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_25415_2 1574422.A0A0A1ENW9_9CIRC 2.96e-37 141.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_231973_1 179237.Q8W6H9_9CAUD 3.35e-19 89.4 4QFIA@10239|Viruses,4QZJU@35237|dsDNA viruses no RNA stage,4QU30@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_195530_3 929704.Myrod_2723 0.000841 52.8 COG3291@1|root,COG3291@2|Bacteria,4NFRR@976|Bacteroidetes,1I0VP@117743|Flavobacteriia 976|Bacteroidetes S PKD domain - - - - - - - - - - - - Beta_helix,NosD,PKD k59_62133_3 1088721.NSU_0331 1.67e-45 150.0 2ECZ3@1|root,336W5@2|Bacteria,1NESK@1224|Proteobacteria,2UI3A@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_49892_1 1268635.Loa_01840 0.000358 49.3 COG3064@1|root,COG3064@2|Bacteria 2|Bacteria M translation initiation factor activity cobN - - - - - - - - - - - Collagen,DUF1236,Phage_fiber_C,phage_tail_N k59_293808_17 580332.Slit_1922 1.12e-49 185.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,2VM59@28216|Betaproteobacteria 28216|Betaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_172277_1 1986029.Q9MBM3_9VIRU 2.18e-11 65.9 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_244919_10 1120949.KB903356_gene8520 2.65e-08 62.8 COG1573@1|root,COG1573@2|Bacteria,2GMPT@201174|Actinobacteria,4DA7F@85008|Micromonosporales 201174|Actinobacteria L Uracil-DNA glycosylase dpo - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_87187_1 1692247.A0A0K1RL30_9CIRC 3.77e-33 129.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_75014_2 1074309.G1JX92_9CAUD 8.75e-13 64.3 4QF4C@10239|Viruses,4QXEM@35237|dsDNA viruses no RNA stage,4QST2@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_75014_6 1105171.H2A0E8_9CAUD 4.22e-37 157.0 4QAKZ@10239|Viruses,4QYAE@35237|dsDNA viruses no RNA stage,4QPYH@28883|Caudovirales,4QM57@10699|Siphoviridae 10699|Siphoviridae S intein-mediated protein splicing - - - - - - - - - - - - - k59_75014_7 1211115.ALIQ01000188_gene655 6.4e-89 301.0 28MS5@1|root,2ZB0J@2|Bacteria,1PTV9@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_75014_20 552396.HMPREF0863_01423 2.61e-64 220.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,3VTR1@526524|Erysipelotrichia 526524|Erysipelotrichia L SNF2 family N-terminal domain - - - - - - - - - - - - SNF2_N k59_75014_22 240302.BN982_00207 2.23e-70 246.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,4H9Z7@91061|Bacilli 91061|Bacilli L DNA polymerase - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_354716_2 1234888.K0A2R8_9VIRU 2.28e-54 184.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_13677_2 1692258.A0A0K1RL51_9CIRC 2.26e-52 180.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_50890_1 1618251.A0A0C5I2L8_9CIRC 8.72e-30 121.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_50890_2 1379711.S5SYC9_9CIRC 1.02e-12 68.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_342409_2 1200557.JHWV01000006_gene1732 8.31e-26 106.0 COG5362@1|root,COG5362@2|Bacteria,1UI9S@1239|Firmicutes 1239|Firmicutes S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_306137_1 1123508.JH636441_gene3521 9.9e-50 172.0 COG0535@1|root,COG0535@2|Bacteria,2J3DJ@203682|Planctomycetes 203682|Planctomycetes S Iron-sulfur cluster-binding domain - - - - - - - - - - - - Radical_SAM,SPASM k59_354721_1 1120936.KB907208_gene1066 3.79e-57 199.0 28MN1@1|root,2ZAXN@2|Bacteria,2H2TF@201174|Actinobacteria 201174|Actinobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6C k59_210164_1 1122173.AXVL01000018_gene424 1.2e-30 130.0 COG5283@1|root,COG5283@2|Bacteria,37AJ8@32066|Fusobacteria 32066|Fusobacteria K Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_136679_1 278957.ABEA03000174_gene3395 9.17e-30 114.0 2DRE2@1|root,33BCC@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_270311_2 521674.Plim_2345 4.16e-07 50.4 2E3N9@1|root,33M91@2|Bacteria,2J1E4@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_39294_1 1986029.Q9MBM8_9VIRU 5.29e-186 540.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_319418_1 1379725.S5TMY9_9CIRC 1.76e-26 112.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_112457_1 1609634.A0A0C5AFV4_9VIRU 2.39e-10 60.5 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_355678_1 290400.Jann_2321 1.09e-28 114.0 COG3108@1|root,COG3772@1|root,COG3108@2|Bacteria,COG3772@2|Bacteria,1QYHH@1224|Proteobacteria,2UGWI@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_100609_1 2002.JOEQ01000005_gene3654 1.01e-10 65.5 COG3740@1|root,COG3740@2|Bacteria,2II2M@201174|Actinobacteria,4EP2Y@85012|Streptosporangiales 201174|Actinobacteria S Phage prohead protease, HK97 family - - - - - - - - - - - - - k59_197785_4 945713.IALB_0073 2.7e-34 148.0 COG3941@1|root,COG3941@2|Bacteria 2|Bacteria O tape measure - - - - - - - - - - - - - k59_246129_1 105154.Q9MBU0_9VIRU 6.93e-13 72.8 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_126383_2 536019.Mesop_3359 3.17e-74 230.0 COG5565@1|root,COG5565@2|Bacteria,1RHD5@1224|Proteobacteria,2UB9H@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_223647_1 1692249.A0A0K1RLN8_9CIRC 7.92e-18 84.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_296237_1 697281.Mahau_2911 5.38e-42 152.0 COG4653@1|root,COG4653@2|Bacteria,1TS6A@1239|Firmicutes,24994@186801|Clostridia,42FCQ@68295|Thermoanaerobacterales 186801|Clostridia S TIGRFAM phage major capsid protein, HK97 family - - - - - - - - - - - - Phage_capsid k59_332897_3 1079998.H8ZMF1_9CAUD 4.18e-50 174.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QII1@10662|Myoviridae 10662|Myoviridae S N-methyltransferase activity - - - - - - - - - - - - - k59_211734_1 511.JT27_18240 2.82e-11 65.1 COG4106@1|root,COG4106@2|Bacteria 2|Bacteria FG trans-aconitate 2-methyltransferase activity - - 2.1.1.197 ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 - - - Dimerisation2,Methyltransf_11,Methyltransf_2,Methyltransf_23,Methyltransf_25,NodS k59_271744_2 1345023.M467_06655 1.77e-10 63.5 COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,4HBHA@91061|Bacilli,3WEPN@539002|Bacillales incertae sedis 91061|Bacilli K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 k59_89983_2 1692252.A0A0K1RLN6_9CIRC 2.97e-28 117.0 4QCY8@10239|Viruses,4QUMD@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_89983_3 1692252.A0A0K1RL35_9CIRC 7.79e-66 210.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_102031_1 266779.Meso_1200 5.27e-37 135.0 COG0863@1|root,COG0863@2|Bacteria,1NQ2A@1224|Proteobacteria,2UJ12@28211|Alphaproteobacteria,43KMC@69277|Phyllobacteriaceae 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase k59_247590_1 1234888.K0A2J2_9VIRU 3.35e-27 114.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_381373_1 1618248.A0A0C5IB82_9CIRC 3.09e-11 63.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_248754_2 691965.D4P7B9_9CAUD 1.5e-30 112.0 4QFDH@10239|Viruses,4QWV5@35237|dsDNA viruses no RNA stage,4QPB8@28883|Caudovirales,4QKNN@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_248754_3 691965.D4P7C0_9CAUD 4.55e-64 198.0 4QDUR@10239|Viruses,4QVMY@35237|dsDNA viruses no RNA stage,4QU8R@28883|Caudovirales,4QKNQ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_225033_1 1609634.A0A0C5AFT2_9VIRU 8.97e-45 154.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_322137_3 1219035.NT2_13_00580 3.64e-70 234.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_382455_2 330084.JNYZ01000003_gene2277 3.94e-28 108.0 2BM0Q@1|root,32FHM@2|Bacteria,2IK53@201174|Actinobacteria,4ECAS@85010|Pseudonocardiales 201174|Actinobacteria - - - - - - - - - - - - - - - k59_78953_1 428125.CLOLEP_01411 1.76e-45 162.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia,3WNJZ@541000|Ruminococcaceae 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_78953_2 691965.D4P7D6_9CAUD 5.46e-33 132.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_115073_1 1484157.PSNIH2_13390 1.67e-126 399.0 28JKJ@1|root,2Z9DD@2|Bacteria,1MUN2@1224|Proteobacteria,1RQIP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage P22-like portal protein - - - - - - - - - - - - P22_portal k59_115073_2 318586.Pden_3765 1.06e-32 116.0 2D1MV@1|root,32TAZ@2|Bacteria,1N45A@1224|Proteobacteria,2UEJT@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage protein (N4 Gp49/phage Sf6 gene 66) family - - - - - - - - - - - - Phage_gp49_66 k59_115073_5 742725.HMPREF9450_02130 1.53e-24 98.6 2DNV9@1|root,32ZB3@2|Bacteria,4NV7Y@976|Bacteroidetes,2FTAS@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_115073_7 1124991.MU9_2905 1.47e-138 421.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,1RY0J@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_248884_1 1045858.Bint_1533 5.6e-112 347.0 COG5511@1|root,COG5511@2|Bacteria 2|Bacteria F Phage portal protein, lambda family JD73_18735 - - - - - - - - - - - Phage_portal_2 k59_382459_1 1618250.A0A0C5I9W8_9CIRC 5.51e-18 90.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_287197_1 91464.S7335_1514 2.27e-06 55.5 COG1216@1|root,COG1216@2|Bacteria,1G2MT@1117|Cyanobacteria,1H3HJ@1129|Synechococcus 1117|Cyanobacteria M Glycosyltransferase like family 2 - - - - - - - - - - - - Glyco_hydro_2_C,Glycos_transf_2 k59_309955_1 1618248.A0A0C5IB82_9CIRC 1.43e-18 85.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_309955_3 1692244.A0A0K1RLR5_9CIRC 6.78e-49 166.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_139695_1 160488.PP_2269 1.13e-27 106.0 COG3023@1|root,COG3023@2|Bacteria,1N032@1224|Proteobacteria,1SA9C@1236|Gammaproteobacteria 1236|Gammaproteobacteria V N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2 k59_260703_2 1502724.FF80_03116 4.24e-61 202.0 COG0175@1|root,COG0175@2|Bacteria,1QZJ1@1224|Proteobacteria,2U233@28211|Alphaproteobacteria 28211|Alphaproteobacteria EH sulfate reduction - - - - - - - - - - - - - k59_186247_1 78245.Xaut_1087 9.79e-41 152.0 COG0358@1|root,COG3598@1|root,COG0358@2|Bacteria,COG3598@2|Bacteria,1R4EA@1224|Proteobacteria 1224|Proteobacteria L AAA domain - - - ko:K06919 - - - - ko00000 - - - AAA_25,PriCT_2,Prim_Zn_Ribbon,Toprim_3 k59_322321_1 1165096.ARWF01000001_gene594 5.54e-13 70.5 COG2268@1|root,COG2268@2|Bacteria,1P39U@1224|Proteobacteria,2VMEW@28216|Betaproteobacteria 28216|Betaproteobacteria S prohibitin homologues - - - - - - - - - - - - Band_7 k59_383571_1 595536.ADVE02000001_gene2795 1.46e-37 137.0 COG1216@1|root,COG2227@1|root,COG1216@2|Bacteria,COG2227@2|Bacteria,1NA3Z@1224|Proteobacteria,2UGVH@28211|Alphaproteobacteria 28211|Alphaproteobacteria H PFAM Methyltransferase type 11 - - - - - - - - - - - - Methyltransf_11 k59_68501_2 1131451.O1K_00290 1.82e-05 50.8 COG1876@1|root,COG1876@2|Bacteria,1MXWT@1224|Proteobacteria,1SMWE@1236|Gammaproteobacteria,1X8FF@135614|Xanthomonadales 135614|Xanthomonadales M D-alanyl-D-alanine carboxypeptidase - - - ko:K17733 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M15_4 k59_141128_1 1121921.KB898706_gene3039 4.97e-87 281.0 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,1RQFD@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage terminase, large subunit Z012_12305 - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_43780_1 66377.JOBH01000032_gene5964 2.31e-15 77.8 COG0863@1|root,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - 2.1.1.72 ko:K00571,ko:K07319 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_214839_1 11082.PRO_0000037746 5.41e-59 198.0 4QBXT@10239|Viruses,4R138@439488|ssRNA viruses,4R0R1@35278|ssRNA positive-strand viruses no DNA stage 10239|Viruses K ATP-dependent helicase activity - GO:0001510,GO:0001959,GO:0001960,GO:0002682,GO:0002683,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003725,GO:0003727,GO:0003824,GO:0004482,GO:0004483,GO:0005488,GO:0005575,GO:0006139,GO:0006370,GO:0006396,GO:0006397,GO:0006508,GO:0006725,GO:0006807,GO:0006810,GO:0006897,GO:0006898,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008171,GO:0008173,GO:0008174,GO:0008233,GO:0008757,GO:0009451,GO:0009452,GO:0009605,GO:0009607,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009968,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010646,GO:0010648,GO:0010941,GO:0016032,GO:0016070,GO:0016071,GO:0016192,GO:0016556,GO:0016740,GO:0016741,GO:0016787,GO:0018995,GO:0019012,GO:0019031,GO:0019048,GO:0019049,GO:0019050,GO:0019054,GO:0019058,GO:0019065,GO:0019068,GO:0019219,GO:0019222,GO:0019538,GO:0020012,GO:0023051,GO:0023057,GO:0030260,GO:0030430,GO:0030682,GO:0030683,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031347,GO:0031348,GO:0032259,GO:0032991,GO:0032993,GO:0033592,GO:0033643,GO:0033646,GO:0033655,GO:0033668,GO:0034641,GO:0035821,GO:0036260,GO:0036265,GO:0036338,GO:0039502,GO:0039503,GO:0039526,GO:0039713,GO:0039714,GO:0042981,GO:0043067,GO:0043069,GO:0043170,GO:0043207,GO:0043412,GO:0043414,GO:0043487,GO:0043489,GO:0043656,GO:0043657,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044068,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044403,GO:0044409,GO:0044413,GO:0044414,GO:0044415,GO:0044419,GO:0044423,GO:0044501,GO:0044531,GO:0044532,GO:0044766,GO:0045069,GO:0045070,GO:0045088,GO:0045824,GO:0045934,GO:0046483,GO:0046718,GO:0046755,GO:0046762,GO:0046794,GO:0048518,GO:0048519,GO:0048523,GO:0048524,GO:0048583,GO:0048585,GO:0050690,GO:0050776,GO:0050777,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051252,GO:0051253,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051806,GO:0051807,GO:0051817,GO:0051828,GO:0051832,GO:0051833,GO:0051834,GO:0052027,GO:0052029,GO:0052031,GO:0052037,GO:0052040,GO:0052041,GO:0052150,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052248,GO:0052250,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052433,GO:0052490,GO:0052493,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0060147,GO:0060149,GO:0060255,GO:0060338,GO:0060339,GO:0060548,GO:0060759,GO:0060761,GO:0060966,GO:0060967,GO:0060968,GO:0060969,GO:0065007,GO:0065008,GO:0071704,GO:0072583,GO:0075109,GO:0075111,GO:0075112,GO:0075114,GO:0075136,GO:0075509,GO:0075512,GO:0075528,GO:0080009,GO:0080090,GO:0080134,GO:0090304,GO:0097159,GO:0097617,GO:0098657,GO:0106005,GO:0140096,GO:0140098,GO:1900368,GO:1900369,GO:1901360,GO:1901363,GO:1901564,GO:1902369,GO:1902579,GO:1903900,GO:1903902,GO:1990814,GO:1990904 - - - - - - - - - - - k59_347795_3 563192.HMPREF0179_02917 6.55e-38 141.0 28HHC@1|root,2Z7T2@2|Bacteria,1PZ57@1224|Proteobacteria 1224|Proteobacteria S AAA domain - - - - - - - - - - - - AAA_24 k59_383587_1 1211844.CBLM010000016_gene1482 0.00026 51.2 COG3941@1|root,COG5412@1|root,COG3941@2|Bacteria,COG5412@2|Bacteria,1TQDE@1239|Firmicutes,3VQ26@526524|Erysipelotrichia 526524|Erysipelotrichia D tape measure - - - - - - - - - - - - - k59_311388_1 1618238.A0A0C5IB41_9CIRC 3.7e-19 90.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_116628_2 670292.JH26_14715 2.18e-06 48.5 COG3926@1|root,COG3926@2|Bacteria,1MVXW@1224|Proteobacteria,2TT3H@28211|Alphaproteobacteria,1JXT2@119045|Methylobacteriaceae 28211|Alphaproteobacteria S Predicted Peptidoglycan domain - - - - - - - - - - - - Glyco_hydro_108,PG_binding_1,PG_binding_3 k59_7654_2 1692249.A0A0K1RL40_9CIRC 3.15e-67 216.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_371739_1 756272.Plabr_2550 1.49e-18 89.7 COG2165@1|root,COG2165@2|Bacteria,2J1H8@203682|Planctomycetes 203682|Planctomycetes NU TIGRFAM prepilin-type N-terminal cleavage methylation domain - - - - - - - - - - - - N_methyl k59_203430_1 196490.AUEZ01000050_gene334 2.02e-35 134.0 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,2TV42@28211|Alphaproteobacteria,3JXEI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Phage terminase large subunit - - - ko:K06909 - - - - ko00000 - - - Terminase_3 k59_385064_1 686340.Metal_3073 6.09e-13 83.2 2DBPZ@1|root,2ZABJ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_155252_2 886293.Sinac_1136 1.91e-10 64.7 COG0500@1|root,COG2226@2|Bacteria,2J1GI@203682|Planctomycetes 203682|Planctomycetes Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 k59_228539_2 471875.RUMLAC_01253 1.98e-41 158.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia,3WGP3@541000|Ruminococcaceae 186801|Clostridia L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k59_118084_1 1327035.R4JQC6_9CAUD 2.4e-35 130.0 4QAIJ@10239|Viruses,4QPXI@28883|Caudovirales,4QM02@10699|Siphoviridae 10699|Siphoviridae S C-5 cytosine-specific DNA methylase - - - - - - - - - - - - - k59_82246_4 1121289.JHVL01000003_gene2199 8.03e-07 56.2 COG1191@1|root,COG1191@2|Bacteria,1TP9K@1239|Firmicutes,248M0@186801|Clostridia,36EEW@31979|Clostridiaceae 186801|Clostridia K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released fliA - - ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 - - - ko00000,ko00001,ko02035,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 k59_301543_1 1325372.N0DQT7_9CAUD 1.09e-56 196.0 4QAW1@10239|Viruses,4QWUW@35237|dsDNA viruses no RNA stage,4QR8A@28883|Caudovirales,4QJW9@10662|Myoviridae 10662|Myoviridae S nucleic acid binding - - - - - - - - - - - - - k59_9029_2 1986029.Q9MBM8_9VIRU 6.03e-57 193.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_70191_3 1219035.NT2_13_00580 5.11e-71 237.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_20064_2 883078.HMPREF9695_04244 6.53e-16 78.2 COG1525@1|root,COG1525@2|Bacteria,1N145@1224|Proteobacteria,2UCUE@28211|Alphaproteobacteria,3JTEQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Staphylococcal nuclease homologue MA20_39240 - - - - - - - - - - - SNase k59_313032_2 1408287.AXUR01000012_gene2261 2.55e-13 72.4 COG2071@1|root,COG2071@2|Bacteria,379BM@32066|Fusobacteria 32066|Fusobacteria S Peptidase C26 - - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 k59_276364_5 1367847.JCM7686_2415 1.32e-17 93.2 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TR3P@28211|Alphaproteobacteria,2PVGQ@265|Paracoccus 28211|Alphaproteobacteria I AMP-binding enzyme - - - - - - - - - - - - AMP-binding,AMP-binding_C k59_95137_2 172088.AUGA01000071_gene7567 8.66e-20 94.7 COG3740@1|root,COG3740@2|Bacteria,1QVIJ@1224|Proteobacteria,2TVIM@28211|Alphaproteobacteria,3K0XM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Caudovirus prohead serine protease - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_351105_4 742733.HMPREF9469_05074 3.32e-23 99.0 2A0KC@1|root,2ZGJK@2|Bacteria,1V2JS@1239|Firmicutes,24H6R@186801|Clostridia,222B7@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_10428_1 225937.HP15_3095 5.85e-82 252.0 COG4128@1|root,COG4128@2|Bacteria,1N0I7@1224|Proteobacteria,1SAH8@1236|Gammaproteobacteria,46BMP@72275|Alteromonadaceae 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) zot GO:0001906,GO:0006810,GO:0006996,GO:0007010,GO:0008150,GO:0009405,GO:0009987,GO:0016043,GO:0031640,GO:0035821,GO:0042044,GO:0042045,GO:0044364,GO:0044419,GO:0051179,GO:0051234,GO:0051704,GO:0070633,GO:0071840 - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_59377_1 313596.RB2501_01256 7.75e-40 136.0 COG3108@1|root,COG3108@2|Bacteria,4NV14@976|Bacteroidetes,1I63W@117743|Flavobacteriia 976|Bacteroidetes S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k59_230278_1 345341.KUTG_05496 6.77e-29 126.0 COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4DXGE@85010|Pseudonocardiales 201174|Actinobacteria L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity - - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k59_205194_1 445972.ANACOL_00919 9.55e-33 127.0 2CC4J@1|root,2Z7W8@2|Bacteria,1UX5W@1239|Firmicutes,24DCZ@186801|Clostridia,3WGCS@541000|Ruminococcaceae 186801|Clostridia S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_241347_1 1234888.K0A2J2_9VIRU 1.4e-61 205.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_35520_2 1618247.A0A0C5IMK7_9CIRC 5.08e-07 54.7 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_21611_1 1227349.C170_21765 5.13e-56 192.0 29WPN@1|root,30IAJ@2|Bacteria,1TXQ7@1239|Firmicutes,4I6RD@91061|Bacilli,26UGH@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - k59_132859_1 78898.MVEG_05265T0 2.74e-07 60.5 COG1241@1|root,KOG0480@2759|Eukaryota,38B9W@33154|Opisthokonta,3NWN6@4751|Fungi 4751|Fungi L MCM OB domain - - - - - - - - - - - - MCM,MCM_OB k59_35521_1 394503.Ccel_3060 4.65e-85 269.0 COG0553@1|root,COG0553@2|Bacteria,1TP2C@1239|Firmicutes,24DVA@186801|Clostridia,36FNM@31979|Clostridiaceae 186801|Clostridia L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_277941_1 1177928.TH2_09464 1.46e-21 91.3 COG3773@1|root,COG3773@2|Bacteria,1RH3D@1224|Proteobacteria,2UAUQ@28211|Alphaproteobacteria,2JT2U@204441|Rhodospirillales 204441|Rhodospirillales M Cell Wall Hydrolase - - - - - - - - - - - - Hydrolase_2 k59_265370_1 326424.FRAAL6246 4.01e-15 83.2 COG4124@1|root,COG4124@2|Bacteria,2GN8K@201174|Actinobacteria 201174|Actinobacteria G Belongs to the glycosyl hydrolase 26 family - - - - - - - - - - - - Glyco_hydro_26 k59_277942_3 1609634.A0A0C5AFT2_9VIRU 4.99e-27 107.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_119756_2 1234888.K0A2J2_9VIRU 3.73e-54 185.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_230402_2 1168281.I3PV02_9CAUD 7.94e-19 82.0 4QD1J@10239|Viruses,4QW7G@35237|dsDNA viruses no RNA stage,4QQDR@28883|Caudovirales,4QNSF@10744|Podoviridae 10744|Podoviridae S Protein of unknown function (DUF1364) - - - - - - - - - - - - - k59_266658_2 1618257.A0A0C5IBI9_9CIRC 1.24e-80 251.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388285_5 145579.H_BPPHM 8.97e-05 50.1 4QCA6@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_388285_6 1385658.U5KPZ6_9VIRU 6.62e-201 577.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_242991_1 196367.JNFG01000015_gene3881 2.63e-12 77.0 2DM1V@1|root,31D5J@2|Bacteria,1QWVQ@1224|Proteobacteria,2WH21@28216|Betaproteobacteria,1K6TV@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_376582_2 1385658.U5KPZ6_9VIRU 1.36e-184 536.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_376582_4 1385658.U5KNR1_9VIRU 1.4e-64 214.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_266662_1 1385658.U5KPZ6_9VIRU 1.54e-98 307.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_388346_2 77635.BISU_0470 9.53e-05 52.4 28MKK@1|root,2ZAWR@2|Bacteria,2IS2W@201174|Actinobacteria,4D1DD@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_364285_2 701347.Entcl_1833 8.5e-12 70.5 COG0847@1|root,COG0847@2|Bacteria,1R9YS@1224|Proteobacteria,1S23K@1236|Gammaproteobacteria,3X29R@547|Enterobacter 1236|Gammaproteobacteria L 3' exoribonuclease, RNase T-like - - - ko:K10906 - - - - ko00000,ko01000,ko03400 - - - DUF5051,Exonuc_VIII k59_364285_3 329254.Q2NPF7_9CAUD 2.49e-36 129.0 4QB0U@10239|Viruses,4QZQJ@35237|dsDNA viruses no RNA stage,4QR5X@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_388349_1 1692246.A0A0K1RLM8_9CIRC 2.99e-22 95.9 4QBFZ@10239|Viruses,4QUKU@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_364296_1 1328313.DS2_19166 3.67e-21 92.8 2CI0W@1|root,2Z81W@2|Bacteria,1R9FZ@1224|Proteobacteria,1S0NA@1236|Gammaproteobacteria,46B4Q@72275|Alteromonadaceae 1236|Gammaproteobacteria S Phage X family - - - - - - - - - - - - Phage_CRI,Phage_X k59_388350_3 1126411.I1TEL3_9CIRC 1.24e-30 123.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_267171_6 1150474.JQJI01000004_gene365 0.000384 52.0 COG0210@1|root,COG0210@2|Bacteria,2GC9X@200918|Thermotogae 200918|Thermotogae L PFAM UvrD REP helicase - - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k59_353277_1 1204521.I7A8M7_9CAUD 1.7e-125 403.0 4QCZC@10239|Viruses,4QX3V@35237|dsDNA viruses no RNA stage,4QRH3@28883|Caudovirales,4QHVR@10662|Myoviridae 10662|Myoviridae S Bacterial DNA polymerase III alpha subunit - - - - - - - - - - - - - k59_122305_2 1609634.A0A0C5ANA6_9VIRU 3.94e-26 105.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_328907_1 1192759.AKIB01000023_gene2911 1.78e-31 119.0 COG4725@1|root,COG4725@2|Bacteria,1R553@1224|Proteobacteria,2TRP6@28211|Alphaproteobacteria,2K3SP@204457|Sphingomonadales 204457|Sphingomonadales KT MT-A70 - - - - - - - - - - - - MT-A70 k59_365138_3 1986029.Q9MBM7_9VIRU 5.17e-11 67.0 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_365138_4 1609634.A0A0C5AFV4_9VIRU 2.23e-238 672.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_365138_6 1609634.A0A0C5AFT2_9VIRU 2.33e-142 415.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_219696_3 1589746.A0A0B5A6P7_9CAUD 1.53e-36 150.0 4QB5I@10239|Viruses,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_268106_1 314275.MADE_1014600 7.2e-19 85.1 28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_815_2 66875.JODY01000017_gene569 5.05e-18 82.0 2EGA5@1|root,33A1Y@2|Bacteria,2GSDD@201174|Actinobacteria 201174|Actinobacteria S HNH endonuclease - - - - - - - - - - - - HNH_3 k59_207471_3 186617.M9MJB7_9VIRU 8.08e-05 47.4 4QB1C@10239|Viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_353327_3 1357423.S5MQB5_9CAUD 9.61e-13 71.6 4QGWX@10239|Viruses,4R0MM@35237|dsDNA viruses no RNA stage,4QQAI@28883|Caudovirales,4QI1A@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_280480_1 1123072.AUDH01000050_gene73 7.41e-13 68.9 COG0665@1|root,COG0665@2|Bacteria,1Q6SU@1224|Proteobacteria,2TT4N@28211|Alphaproteobacteria 28211|Alphaproteobacteria E FAD dependent oxidoreductase - - 1.4.3.3 ko:K00273 ko00260,ko00311,ko00330,ko00472,ko01100,ko01130,ko04146,map00260,map00311,map00330,map00472,map01100,map01130,map04146 - R00366,R02457,R02894,R02923,R04221,R07400 RC00006,RC00018,RC00135 ko00000,ko00001,ko01000 - - - DAO,Pyr_redox k59_231667_2 1540097.A0A0A0YRM5_9CAUD 1.6e-08 61.2 4QFCU@10239|Viruses,4QTFF@28883|Caudovirales,4QNUH@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_340918_1 1042163.BRLA_c039420 1.5e-11 72.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4HA1S@91061|Bacilli,271FD@186822|Paenibacillaceae 91061|Bacilli D Ftsk_gamma sftA - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE,Ftsk_gamma k59_365144_1 1517681.HW45_02700 6.76e-29 122.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1QZAD@1224|Proteobacteria,1RYP3@1236|Gammaproteobacteria 1236|Gammaproteobacteria D nuclear chromosome segregation - - - - - - - - - - - - - k59_134337_2 1618259.A0A0C5I2B5_9CIRC 1.84e-92 283.0 4QE84@10239|Viruses,4QUKR@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_182818_3 1476391.X5KNB8_9CAUD 6.7e-22 95.9 4QDXM@10239|Viruses,4QWIX@35237|dsDNA viruses no RNA stage,4QQF6@28883|Caudovirales,4QNXH@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_182818_4 1051675.G0YQH7_9CAUD 4.59e-54 182.0 4QGGR@10239|Viruses,4QZHR@35237|dsDNA viruses no RNA stage,4QUGZ@28883|Caudovirales,4QNY3@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_243683_2 1609634.A0A0C5AFT2_9VIRU 6.03e-20 88.2 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_820_1 105154.Q9MBU6_9VIRU 2.57e-113 350.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_220298_1 105154.Q9MBU6_9VIRU 6.86e-62 206.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_49991_2 1027273.GZ77_05365 1.43e-50 164.0 2E04N@1|root,32VT5@2|Bacteria,1N310@1224|Proteobacteria,1SQVP@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_13081_4 1172188.KB911820_gene2845 7.46e-24 95.9 2F5XY@1|root,33YGK@2|Bacteria,2H6A2@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_317388_1 438753.AZC_3583 4.75e-50 194.0 28IA2@1|root,2Z8CQ@2|Bacteria,1PQM2@1224|Proteobacteria,2TUAP@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_171384_4 411464.DESPIG_01289 0.000777 46.6 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,43E94@68525|delta/epsilon subdivisions,2X01M@28221|Deltaproteobacteria,2M9TF@213115|Desulfovibrionales 28221|Deltaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_110764_1 1609634.A0A0C5AFV4_9VIRU 2.47e-80 260.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_1375_3 1068978.AMETH_6272 1.65e-07 53.5 2B2ME@1|root,31V6U@2|Bacteria,2IIMI@201174|Actinobacteria,4EDMY@85010|Pseudonocardiales 201174|Actinobacteria - - - - - - - - - - - - - - Phage_connect_1 k59_147236_1 1085623.GNIT_1814 2.52e-54 187.0 2CYA9@1|root,32T3V@2|Bacteria,1RGRN@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_365635_1 243231.GSU3593 1.51e-41 146.0 2E631@1|root,330S3@2|Bacteria,1NJ41@1224|Proteobacteria,430SA@68525|delta/epsilon subdivisions,2WVRB@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_171386_1 107636.JQNK01000002_gene125 2.96e-12 71.6 COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,2TRFR@28211|Alphaproteobacteria,37042@31993|Methylocystaceae 28211|Alphaproteobacteria S Phage portal protein - - - - - - - - - - - - Phage_portal k59_317392_2 665942.HMPREF1022_03280 1.02e-20 95.9 2DUXE@1|root,32UY2@2|Bacteria,1N2YI@1224|Proteobacteria,430A8@68525|delta/epsilon subdivisions,2WVIN@28221|Deltaproteobacteria,2MCZ8@213115|Desulfovibrionales 28221|Deltaproteobacteria S Phage T7 capsid assembly protein - - - - - - - - - - - - Phage_T7_Capsid k59_256488_1 1385658.U5KPZ6_9VIRU 9.27e-71 231.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_353900_1 1294142.CINTURNW_0562 7.61e-24 100.0 COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,36DKZ@31979|Clostridiaceae 186801|Clostridia E Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - RadC k59_353900_7 1907.SGLAU_07020 5.51e-05 47.8 COG0457@1|root,COG1396@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,2GNQ9@201174|Actinobacteria 201174|Actinobacteria K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_19,HTH_3,HTH_31,SNAP,TPR_12,TPR_16 k59_244164_3 1618241.A0A0C5I2I4_9CIRC 5.09e-107 322.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_293154_1 1121926.AXWO01000002_gene1566 5.8e-14 75.1 COG3757@1|root,COG3757@2|Bacteria,2GKS0@201174|Actinobacteria,4EY4F@85014|Glycomycetales 201174|Actinobacteria M PFAM glycoside hydrolase family 25 - - - - - - - - - - - - Glyco_hydro_25 k59_195804_1 1234888.K0A2J2_9VIRU 3.37e-28 114.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_244821_1 1380394.JADL01000001_gene2581 4.19e-13 79.7 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,2U1P9@28211|Alphaproteobacteria,2JX6C@204441|Rhodospirillales 204441|Rhodospirillales S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_257244_1 1618260.A0A0C5I2C5_9CIRC 2.26e-68 217.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_208970_1 272952.HpaP809118 1.39e-13 83.6 COG0553@1|root,KOG0384@2759|Eukaryota,3QB66@4776|Peronosporales 4776|Peronosporales K SNF2 family N-terminal domain - - 3.6.4.12 ko:K14437 - - - - ko00000,ko01000,ko03036 - - - Chromo,Helicase_C,SNF2_N k59_257330_5 1100721.ALKO01000016_gene1463 9.12e-11 67.8 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VIA1@28216|Betaproteobacteria,4AC5G@80864|Comamonadaceae 28216|Betaproteobacteria KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance spoT - 2.7.6.5,3.1.7.2 ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - - ACT_4,HD_4,RelA_SpoT,TGS k59_354610_1 2003327.CAPSD_BPCHP 7.27e-19 88.2 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_354610_6 145579.CAPSD_BPPHM 2.79e-78 259.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_63153_1 1234888.K0A2J2_9VIRU 4.48e-84 270.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_63153_5 1234888.K0A2J2_9VIRU 1.21e-34 132.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_172269_1 272626.lin1248 5.21e-05 48.9 COG4570@1|root,COG4570@2|Bacteria,1VF2H@1239|Firmicutes,4HJ0V@91061|Bacilli 91061|Bacilli L holliday junction resolvase rusA - - - - - - - - - - - RusA k59_160296_1 1574422.A0A0A1ENW9_9CIRC 3.66e-26 107.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_147816_1 1556290.A0A0A0RT35_9CAUD 1.56e-116 351.0 4QAWG@10239|Viruses,4QPII@28883|Caudovirales,4QKWY@10699|Siphoviridae 10699|Siphoviridae S DNA helicase activity - - - - - - - - - - - - - k59_306596_1 1219035.NT2_13_00580 1.05e-22 99.8 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_160817_2 536019.Mesop_3763 8.07e-40 148.0 2EAGC@1|root,334JN@2|Bacteria,1N1US@1224|Proteobacteria,2UEQF@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_124573_2 1443113.LC20_04769 1.75e-11 62.0 COG2105@1|root,COG2105@2|Bacteria,1RH3X@1224|Proteobacteria,1S68T@1236|Gammaproteobacteria,41G67@629|Yersinia 1236|Gammaproteobacteria S Gamma-glutamyl cyclotransferase, AIG2-like ytfP GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - GGACT k59_233614_2 1379722.S5SY31_9CIRC 4.43e-72 225.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_75608_2 1172188.KB911820_gene2873 6.07e-14 74.7 COG0305@1|root,COG0305@2|Bacteria 2|Bacteria L Participates in initiation and elongation during chromosome replication - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - AAA_25,DnaB,DnaB_C k59_245509_3 1385658.U5KPZ6_9VIRU 5.47e-82 260.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_209740_3 622312.ROSEINA2194_01264 1.6e-26 105.0 COG0270@1|root,COG0270@2|Bacteria,1VSZI@1239|Firmicutes,24YBG@186801|Clostridia 186801|Clostridia L C-5 cytosine-specific DNA methylase - - - - - - - - - - - - DNA_methylase k59_342801_2 1034101.G1D1G4_9CAUD 6.56e-82 259.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales 28883|Caudovirales S N-methyltransferase activity - - - - - - - - - - - - - k59_306602_1 742740.HMPREF9474_02265 1.19e-30 117.0 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia,222RY@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_87840_1 1235792.C808_00061 2.59e-18 83.6 29CPM@1|root,2ZZMW@2|Bacteria,1V5MJ@1239|Firmicutes,25HQ9@186801|Clostridia 186801|Clostridia S VRR_NUC - - - - - - - - - - - - VRR_NUC k59_355140_1 1986029.Q9MBM3_9VIRU 5.09e-48 165.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_136316_1 683083.C414_000260170 1.38e-35 140.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,42QKN@68525|delta/epsilon subdivisions,2YNMS@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_75671_3 1609634.A0A0C5ANA6_9VIRU 3.6e-06 54.7 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_75671_6 1385658.U5KNR1_9VIRU 2.74e-44 160.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_64311_4 1392487.JIAD01000001_gene523 3.62e-64 218.0 COG4695@1|root,COG4695@2|Bacteria,1TP8B@1239|Firmicutes,2497C@186801|Clostridia,25VW6@186806|Eubacteriaceae 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_64311_5 398767.Glov_1679 5.65e-30 116.0 COG3740@1|root,COG3740@2|Bacteria,1NHKT@1224|Proteobacteria,433JC@68525|delta/epsilon subdivisions,2WYCB@28221|Deltaproteobacteria 28221|Deltaproteobacteria S PFAM Peptidase U35, phage prohead HK97 - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78 k59_64311_6 335283.Neut_1469 5.2e-62 213.0 COG4653@1|root,COG4653@2|Bacteria,1MWU1@1224|Proteobacteria,2VP0D@28216|Betaproteobacteria,374H7@32003|Nitrosomonadales 28216|Betaproteobacteria S PFAM phage major capsid protein, HK97 - - - - - - - - - - - - Phage_capsid k59_136777_2 1300345.LF41_2410 4.71e-14 71.6 COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria 1224|Proteobacteria KT HNH endonuclease - - - - - - - - - - - - HNH_3 k59_39431_1 1618237.A0A0C5IMG6_9CIRC 4.34e-26 112.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_161420_1 1385658.U5KNR1_9VIRU 1.66e-25 105.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_161420_3 1385658.U5KPZ6_9VIRU 1.63e-82 263.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_125208_1 1556290.A0A0A0RQI3_9CAUD 4.65e-101 328.0 4QCZC@10239|Viruses,4QRH3@28883|Caudovirales,4QM07@10699|Siphoviridae 10699|Siphoviridae S Bacterial DNA polymerase III alpha subunit - - - - - - - - - - - - - k59_3639_1 113395.AXAI01000002_gene5437 1.7e-31 120.0 28PTM@1|root,2ZCEU@2|Bacteria,1R5DD@1224|Proteobacteria,2TVG7@28211|Alphaproteobacteria,3JU4C@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_173573_1 1197906.CAJQ02000016_gene198 3.52e-40 150.0 28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TURR@28211|Alphaproteobacteria,3JUCC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_39504_1 665950.HMPREF1025_01958 3.65e-17 77.4 2E0G5@1|root,32W28@2|Bacteria,1VAS0@1239|Firmicutes,24NYA@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_39504_2 644284.Arch_1326 2.28e-06 50.1 2CC1Y@1|root,32S23@2|Bacteria,2IQS5@201174|Actinobacteria,4D61Z@85005|Actinomycetales 201174|Actinobacteria K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA whiB3 - - ko:K18955 - - - - ko00000,ko03000 - - - Whib k59_100721_1 1151292.QEW_3268 9.33e-08 53.1 COG4570@1|root,COG4570@2|Bacteria,1VF2H@1239|Firmicutes,24P18@186801|Clostridia 186801|Clostridia L Endodeoxyribonuclease RusA rusA - - - - - - - - - - - RusA k59_210350_3 349521.HCH_03372 4.67e-46 165.0 COG5492@1|root,COG5492@2|Bacteria,1QZA3@1224|Proteobacteria 1224|Proteobacteria N Polysaccharide lyase - - - - - - - - - - - - Polysacc_lyase k59_14661_1 1379709.S5TMV0_9CIRC 2.45e-27 109.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_331832_2 1986029.Q9MBM3_9VIRU 1.54e-65 216.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_331832_6 105154.Q9MBU3_9VIRU 6.57e-07 57.0 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_331832_7 1385658.U5KPZ6_9VIRU 5.61e-201 577.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_52523_1 247490.KSU1_C1049 3.01e-12 73.6 COG1196@1|root,COG1196@2|Bacteria 2|Bacteria D nuclear chromosome segregation - - - - - - - - - - - - - k59_184852_1 186617.M9M8L2_9VIRU 5.13e-25 103.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_184852_2 105154.Q9MBT9_9VIRU 3.66e-14 69.3 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_184852_4 1609634.A0A0C5AFT2_9VIRU 2.46e-100 304.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_211013_2 395494.Galf_0949 9.22e-33 133.0 COG3723@1|root,COG3723@2|Bacteria,1R6DB@1224|Proteobacteria,2VNV4@28216|Betaproteobacteria 28216|Betaproteobacteria L RecT family recT - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_149752_2 1379711.S5TNC7_9CIRC 2.32e-11 72.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_223047_1 1453500.AT05_01670 1.12e-07 57.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1HXMT@117743|Flavobacteriia 976|Bacteroidetes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_223047_2 604331.AUHY01000010_gene287 7.44e-21 100.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1WIA1@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,Taq-exonuc k59_223047_3 1347392.CCEZ01000060_gene3286 3.52e-06 48.5 2C2JW@1|root,3316C@2|Bacteria,1VFRB@1239|Firmicutes,24R0E@186801|Clostridia,36N0D@31979|Clostridiaceae 186801|Clostridia S Domain of Unknown Function (DUF1599) - - - - - - - - - - - - DUF1599 k59_113173_1 1219035.NT2_13_00580 2.74e-29 119.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_137444_1 1234888.K0A2R8_9VIRU 2.54e-36 136.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_101355_4 1117943.SFHH103_00131 6.99e-112 347.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,2U1P9@28211|Alphaproteobacteria,4BDQ9@82115|Rhizobiaceae 28211|Alphaproteobacteria S DNA packaging protein gp2 - - - - - - - - - - - - Terminase_6,Terminase_6C k59_101355_6 699218.HMPREF0889_0287 7.44e-22 107.0 28HPK@1|root,2Z7XJ@2|Bacteria,1UZP3@1239|Firmicutes,4H2MM@909932|Negativicutes 909932|Negativicutes S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_101355_9 279383.Q5DN38_9CAUD 5.58e-70 229.0 4QFB4@10239|Viruses,4QZ8P@35237|dsDNA viruses no RNA stage,4QSGK@28883|Caudovirales,4QKUP@10699|Siphoviridae 10699|Siphoviridae S viral capsid - - - - - - - - - - - - - k59_101355_15 1121861.KB899915_gene1863 8.22e-96 314.0 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,2TVGJ@28211|Alphaproteobacteria,2JPR0@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_320214_3 948071.S4S2M5_9CAUD 1.35e-58 192.0 4QBD3@10239|Viruses,4QXFU@35237|dsDNA viruses no RNA stage,4QQ7Z@28883|Caudovirales,4QNS1@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_356816_33 1206743.BAGM01000101_gene2582 4.03e-37 144.0 COG4886@1|root,COG4886@2|Bacteria,2GNZ0@201174|Actinobacteria,4FZF9@85025|Nocardiaceae 201174|Actinobacteria S Leucine-rich repeat (LRR) protein - - - - - - - - - - - - - k59_356816_45 365659.smi_0442 2.76e-10 63.5 COG3728@1|root,COG3728@2|Bacteria,1VAD9@1239|Firmicutes,4HKES@91061|Bacilli 91061|Bacilli L Terminase, small subunit - - - ko:K07474 - - - - ko00000 - - - Terminase_2 k59_356816_46 644966.Tmar_0036 1.39e-166 481.0 COG5323@1|root,COG5323@2|Bacteria 2|Bacteria M Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_356816_53 717785.HYPMC_1228 1.7e-61 192.0 2E6JI@1|root,3316K@2|Bacteria,1PP48@1224|Proteobacteria,2UT9Y@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_285482_3 312309.VF_2017 5.79e-41 139.0 2CPEB@1|root,32SIW@2|Bacteria,1MZE0@1224|Proteobacteria,1SARU@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_271783_1 1527493.A0A076G757_9CAUD 1.45e-37 138.0 4QFZK@10239|Viruses,4QTQB@28883|Caudovirales,4QMC2@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_113644_1 1415780.JPOG01000001_gene1752 1.23e-17 87.0 2C5KH@1|root,333J0@2|Bacteria,1NBW7@1224|Proteobacteria,1STP2@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_126427_1 1120936.KB907208_gene1107 1.55e-146 437.0 COG0209@1|root,COG0209@2|Bacteria,2IC1H@201174|Actinobacteria 201174|Actinobacteria F Ribonucleotide reductase, barrel domain - - - - - - - - - - - - Ribonuc_red_lgC k59_356821_1 105154.Q9MBU6_9VIRU 4.54e-76 246.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_162731_1 279238.Saro_3022 1.54e-39 139.0 2C0VP@1|root,32ZQ9@2|Bacteria,1NENB@1224|Proteobacteria,2UGGI@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_101970_1 105154.Q9MBU2_9VIRU 2.42e-18 83.6 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_175090_2 1226994.AMZB01000137_gene5410 2.11e-41 152.0 2CYA9@1|root,32T3V@2|Bacteria,1RGRN@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_15956_1 1385658.U5KPZ6_9VIRU 9.98e-62 209.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_40941_1 225937.HP15_670 8.99e-34 136.0 COG4653@1|root,COG4653@2|Bacteria,1MWMB@1224|Proteobacteria,1S4MJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_247629_1 358220.C380_14040 6.62e-62 197.0 COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,2VNC5@28216|Betaproteobacteria,4AI1Z@80864|Comamonadaceae 28216|Betaproteobacteria S Protein of unknown function DUF45 - - - ko:K07043 - - - - ko00000 - - - DUF45 k59_175660_1 402626.Rpic_2548 6.26e-54 187.0 COG0464@1|root,COG0464@2|Bacteria,1QU82@1224|Proteobacteria,2WHSD@28216|Betaproteobacteria,1KFRP@119060|Burkholderiaceae 28216|Betaproteobacteria O PFAM Zonular occludens toxin - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_199688_1 768670.Calni_2100 0.000119 50.1 COG0863@1|root,COG4123@1|root,COG0863@2|Bacteria,COG4123@2|Bacteria,2GGPV@200930|Deferribacteres 200930|Deferribacteres L DNA methylase - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_235914_1 862751.SACTE_0387 4.94e-13 70.9 2DMIE@1|root,32RSG@2|Bacteria,2IQEH@201174|Actinobacteria 201174|Actinobacteria K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA - - - ko:K18955 - - - - ko00000,ko03000 - - - Whib k59_66327_1 1385658.U5KNR1_9VIRU 9.65e-70 226.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_66327_4 1385658.U5KPZ6_9VIRU 7.13e-189 547.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_309255_1 926569.ANT_31290 2.66e-26 114.0 COG0739@1|root,COG3103@1|root,COG0739@2|Bacteria,COG4991@2|Bacteria 2|Bacteria T sh3 domain protein - - 3.2.1.96 ko:K01227,ko:K03642 ko00511,map00511 - - - ko00000,ko00001,ko01000 - - - Glucosaminidase,NLPC_P60,Peptidase_M23,SH3_3,SLH k59_297035_2 1357272.AVEO02000145_gene1375 1.57e-29 117.0 COG0175@1|root,COG0175@2|Bacteria,1PZ96@1224|Proteobacteria,1SBUC@1236|Gammaproteobacteria 1236|Gammaproteobacteria EH Phosphoadenosine phosphosulfate reductase family - - - - - - - - - - - - PAPS_reduct k59_381903_1 1288484.APCS01000031_gene2346 6.93e-103 325.0 COG5362@1|root,COG5362@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Terminase_6C k59_321599_2 1380394.JADL01000006_gene5249 2.11e-58 204.0 28QU5@1|root,2ZD9H@2|Bacteria,1RAU8@1224|Proteobacteria,2VC6Q@28211|Alphaproteobacteria,2JY0A@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_235942_1 1500897.JQNA01000002_gene1055 8.91e-15 72.8 COG3926@1|root,COG3926@2|Bacteria,1MVXW@1224|Proteobacteria,2VRGU@28216|Betaproteobacteria,1K5ME@119060|Burkholderiaceae 28216|Betaproteobacteria S Predicted Peptidoglycan domain - - - - - - - - - - - - Glyco_hydro_108,PG_binding_3 k59_272613_3 1487921.DP68_08640 0.000252 44.3 COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,36FK8@31979|Clostridiaceae 186801|Clostridia L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k59_66337_3 1210884.HG799464_gene10908 1.5e-45 163.0 COG0175@1|root,COG0175@2|Bacteria 2|Bacteria EH sulfate reduction - - - - - - - - - - - - PAPS_reduct k59_260190_2 1121124.JNIX01000011_gene1664 4.04e-28 110.0 COG3926@1|root,COG3926@2|Bacteria,1MVXW@1224|Proteobacteria,2TT3H@28211|Alphaproteobacteria 28211|Alphaproteobacteria M secretion activating protein - - - ko:K17733 - - - - ko00000,ko01000,ko01002,ko01011 - - - Glyco_hydro_108,PG_binding_1,PG_binding_3 k59_138973_1 269482.Bcep1808_1144 3.5e-55 189.0 COG0582@1|root,COG0582@2|Bacteria,1NWGS@1224|Proteobacteria,2VKWM@28216|Betaproteobacteria,1K96C@119060|Burkholderiaceae 28216|Betaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k59_309278_1 272568.GDI3673 8.17e-67 214.0 2DVPY@1|root,33WQ8@2|Bacteria,1N9VQ@1224|Proteobacteria,2UIC5@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_381915_2 1125971.ASJB01000083_gene1812 0.000352 43.9 2DQQK@1|root,33842@2|Bacteria,2H10K@201174|Actinobacteria,4ECG5@85010|Pseudonocardiales 201174|Actinobacteria - - - - - - - - - - - - - - HTH_17 k59_66341_1 1048339.KB913029_gene3575 1.05e-45 157.0 COG1351@1|root,COG1351@2|Bacteria,2HCNJ@201174|Actinobacteria 201174|Actinobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant thyX GO:0000166,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0008150,GO:0008152,GO:0008168,GO:0016740,GO:0016741,GO:0032259,GO:0036094,GO:0040007,GO:0042083,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050797,GO:0070402,GO:0097159,GO:1901265,GO:1901363 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - iNJ661.Rv2754c Thy1 k59_66341_2 1347392.CCEZ01000020_gene886 3e-17 81.3 COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia,36I4X@31979|Clostridiaceae 186801|Clostridia F deaminase comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_16949_2 5691.AAZ12463 2.47e-22 108.0 COG0749@1|root,KOG0950@2759|Eukaryota,3XSQV@5653|Kinetoplastida 5653|Kinetoplastida L Mitochondrial DNA polymerase I protein C - - - - - - - - - - - - DNA_pol_A k59_103250_1 550540.Fbal_0142 1.4e-25 105.0 COG0463@1|root,COG0463@2|Bacteria,1MX1N@1224|Proteobacteria,1S06M@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Glycosyl transferase, family 2 - - - - - - - - - - - - Glycos_transf_2 k59_103250_4 944480.ATUV01000001_gene539 1.64e-18 89.0 COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2WMQW@28221|Deltaproteobacteria,2M6II@213113|Desulfurellales 28221|Deltaproteobacteria M Cytidylyltransferase kdsB - 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 k59_103252_1 1385658.U5KNR1_9VIRU 1.57e-33 128.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_200341_2 1386089.N865_18430 3.21e-38 145.0 COG0367@1|root,COG0367@2|Bacteria,2GJIM@201174|Actinobacteria,4FF9I@85021|Intrasporangiaceae 201174|Actinobacteria E Asparagine synthase - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 k59_297797_2 1692257.A0A0K1RL39_9CIRC 2.12e-81 255.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_297797_3 1692242.A0A0K1RKZ2_9CIRC 1.48e-08 60.5 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_213224_2 391937.NA2_19998 1.94e-23 102.0 COG0863@1|root,COG0863@2|Bacteria,1PCSC@1224|Proteobacteria,2U4M6@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_151819_1 320836.Q4ZD45_9CAUD 9.19e-19 92.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_200344_1 1788454.A0A190WHE4_9CIRC 1.75e-06 54.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_358018_11 2754.EH55_13305 8.58e-16 78.6 COG3926@1|root,COG3926@2|Bacteria,3TBJA@508458|Synergistetes 508458|Synergistetes S Predicted Peptidoglycan domain - - - - - - - - - - - - Glyco_hydro_108,PG_binding_3 k59_358018_12 1197951.I6R0Z3_9CAUD 5.56e-10 59.3 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales 28883|Caudovirales S Ribonucleotide reductase, barrel domain - GO:0003674,GO:0003824,GO:0004748,GO:0008150,GO:0008152,GO:0016491,GO:0016725,GO:0016728,GO:0055114,GO:0061731 - - - - - - - - - - - k59_248808_1 1249975.JQLP01000001_gene3212 1.34e-34 137.0 COG0582@1|root,COG0582@2|Bacteria,4NDZJ@976|Bacteroidetes,1HZ88@117743|Flavobacteriia 976|Bacteroidetes L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_5,Phage_int_SAM_5,Phage_integrase k59_260605_2 1618236.A0A0C5IB23_9CIRC 1.48e-34 135.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_151820_3 67267.JNXT01000054_gene2989 1.56e-23 105.0 2F1HE@1|root,33UHX@2|Bacteria,2IH41@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_236505_1 1140.Synpcc7942_2287 5.7e-15 81.6 COG1442@1|root,COG1442@2|Bacteria,1G3Z0@1117|Cyanobacteria 1117|Cyanobacteria M PFAM Glycosyl transferase, family 8 - - - - - - - - - - - - - k59_17697_1 1788452.A0A190WHG0_9CIRC 6.39e-75 234.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_152739_2 1609634.A0A0C5ANA6_9VIRU 3.29e-21 95.1 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_334928_1 1246995.AFR_22960 3.11e-07 57.8 COG4733@1|root,COG4733@2|Bacteria,2H7QD@201174|Actinobacteria,4DJZF@85008|Micromonosporales 201174|Actinobacteria NU Fibronectin type III domain - - 2.7.11.1 ko:K12567 ko05410,ko05414,map05410,map05414 - - - ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812 - - - fn3 k59_358764_2 105154.Q9MBU3_9VIRU 5.09e-10 64.3 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_31249_1 10752.A0MZC7_BPN4 2.23e-17 84.0 4QBY0@10239|Viruses,4QW35@35237|dsDNA viruses no RNA stage,4QQ4Q@28883|Caudovirales,4QNNN@10744|Podoviridae 10744|Podoviridae S UvrD-like helicase C-terminal domain - - - - - - - - - - - - - k59_214037_1 396588.Tgr7_0100 1.54e-17 79.0 COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1RP86@1236|Gammaproteobacteria,1WXFP@135613|Chromatiales 135613|Chromatiales L Belongs to the UPF0758 family - - - ko:K03630 - - - - ko00000 - - - RadC k59_79648_1 1538804.A0A088F6T3_9CAUD 1.58e-15 85.9 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_261344_1 1618236.A0A0C5IB23_9CIRC 1.8e-07 57.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_31250_1 935557.ATYB01000008_gene4846 3.02e-50 169.0 COG1442@1|root,COG1442@2|Bacteria,1QH4S@1224|Proteobacteria,2U9KQ@28211|Alphaproteobacteria,4B9U9@82115|Rhizobiaceae 28211|Alphaproteobacteria M glycosyl transferase family 8 - - - - - - - - - - - - - k59_43113_1 675806.VII_003784 5.88e-09 57.4 COG1196@1|root,COG1196@2|Bacteria,1PPPK@1224|Proteobacteria,1TJ76@1236|Gammaproteobacteria,1Y0QY@135623|Vibrionales 135623|Vibrionales D nuclear chromosome segregation - - - - - - - - - - - - - k59_43113_2 1380390.JIAT01000009_gene1852 5.94e-15 78.2 COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,2GKXQ@201174|Actinobacteria,4CPNU@84995|Rubrobacteria 84995|Rubrobacteria L Participates in initiation and elongation during chromosome replication - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3 k59_358867_3 1121406.JAEX01000040_gene2120 8.43e-05 45.8 2C4D9@1|root,337PW@2|Bacteria,1NE4W@1224|Proteobacteria,42QXQ@68525|delta/epsilon subdivisions,2WMPR@28221|Deltaproteobacteria,2MB2C@213115|Desulfovibrionales 28221|Deltaproteobacteria S Protein of unknown function (DUF1353) - - - - - - - - - - - - DUF1353 k59_6939_2 1609634.A0A0C5ANA6_9VIRU 3.4e-09 62.4 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_92477_1 1609634.A0A0C5AFV4_9VIRU 3.84e-73 237.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_310718_1 1344012.ATMI01000056_gene1743 1.96e-50 187.0 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,1RR0M@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_164863_2 192952.MM_2213 2.22e-21 97.8 arCOG07826@1|root,arCOG07826@2157|Archaea,2XXK4@28890|Euryarchaeota 28890|Euryarchaeota H Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1,Glycos_transf_2 k59_383562_2 1282362.AEAC466_04375 1.55e-13 68.9 2E7GT@1|root,331ZH@2|Bacteria,1NAHD@1224|Proteobacteria,2UHC5@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_335803_1 1385658.U5KNR1_9VIRU 1.55e-25 105.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_80612_2 428125.CLOLEP_01379 3.94e-49 172.0 COG0553@1|root,COG0553@2|Bacteria,1TS9W@1239|Firmicutes,24CGX@186801|Clostridia,3WN6X@541000|Ruminococcaceae 186801|Clostridia KL Helicase conserved C-terminal domain - - - - - - - - - - - - - k59_104735_3 136993.KB900626_gene1862 1.34e-09 60.1 2AMMY@1|root,31CI1@2|Bacteria,1P1VX@1224|Proteobacteria,2UVEF@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_335990_2 637390.AFOH01000025_gene1034 3.07e-11 63.9 COG3772@1|root,COG3772@2|Bacteria,1N0ZQ@1224|Proteobacteria,1S9AE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_93367_1 652103.Rpdx1_1426 1.59e-33 127.0 COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2U6XP@28211|Alphaproteobacteria,3K406@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Dehydrogenase E1 component - - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh k59_215004_3 360910.BAV1477 2.05e-06 49.7 2EK5N@1|root,33DW2@2|Bacteria,1NHDG@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_311538_1 1234888.K0A2J2_9VIRU 1.36e-72 234.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_383726_1 1131814.JAFO01000001_gene2086 6.48e-07 51.6 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,2TT3N@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_227505_3 1609634.A0A0C5AFV4_9VIRU 1.04e-20 92.4 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_19143_1 1385658.U5KPZ6_9VIRU 5.26e-136 406.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_275514_1 310453.XP_007582379.1 0.000785 47.8 COG2227@1|root,KOG1270@2759|Eukaryota,39T8B@33154|Opisthokonta,3NZTD@4751|Fungi,3QNCR@4890|Ascomycota,1ZXRK@147541|Dothideomycetes 4751|Fungi H O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway COQ3 GO:0003674,GO:0003824,GO:0004395,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008757,GO:0009058,GO:0009108,GO:0009987,GO:0010420,GO:0016020,GO:0016740,GO:0016741,GO:0019866,GO:0019898,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032259,GO:0042180,GO:0042181,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0061542,GO:0061543,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.114,2.1.1.222,2.1.1.64 ko:K00568,ko:K00591 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117,M00128 R02175,R04711,R04988,R05614,R07235,R08769,R08771,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11,Methyltransf_23 k59_324717_1 1282362.AEAC466_01380 4.97e-101 313.0 COG2304@1|root,COG2304@2|Bacteria,1QW8J@1224|Proteobacteria,2U1R3@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Trove domain-containing protein - - - - - - - - - - - - TROVE k59_238854_3 1609634.A0A0C5AFV4_9VIRU 2.67e-154 451.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_56883_1 696281.Desru_1219 5.95e-11 66.6 COG1861@1|root,COG1861@2|Bacteria,1U4YD@1239|Firmicutes,24B0X@186801|Clostridia,264GQ@186807|Peptococcaceae 186801|Clostridia M Cytidylyltransferase spsF - - ko:K07257 - - - - ko00000 - - - CTP_transf_3 k59_178919_1 744980.TRICHSKD4_2781 4.47e-13 72.4 COG0863@1|root,COG0863@2|Bacteria,1R7RR@1224|Proteobacteria 1224|Proteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_69308_1 626887.J057_01900 4.08e-18 87.8 2C2XN@1|root,32GT6@2|Bacteria,1REZE@1224|Proteobacteria,1SG9Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria S ERF superfamily - - - - - - - - - - - - ERF k59_262980_3 1480694.DC28_08135 1.56e-15 70.9 COG1476@1|root,COG1476@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_26,HTH_3 k59_262980_4 1122164.JHWF01000020_gene1487 1.74e-06 50.1 COG1914@1|root,COG1914@2|Bacteria,1MW6X@1224|Proteobacteria,1RNA2@1236|Gammaproteobacteria,1JFG2@118969|Legionellales 118969|Legionellales P Natural resistance-associated macrophage protein mntH - - - - - - - - - - - Nramp k59_154453_1 694060.D2K079_9CAUD 2.92e-13 75.5 4QCWQ@10239|Viruses,4QYP8@35237|dsDNA viruses no RNA stage,4QQZU@28883|Caudovirales,4QK15@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_33104_1 344747.PM8797T_23394 4.16e-18 88.2 COG0714@1|root,COG0714@2|Bacteria 2|Bacteria KLT Associated with various cellular activities - - 6.6.1.2 ko:K09882 ko00860,ko01100,map00860,map01100 - R05227 RC02000 ko00000,ko00001,ko01000 - - - AAA_5,CbbQ_C k59_290370_20 749222.Nitsa_1386 1.48e-30 135.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2YMQV@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_33873_1 1459636.NTE_01091 3.03e-28 112.0 COG0468@1|root,arCOG00415@2157|Archaea,41SBA@651137|Thaumarchaeota 651137|Thaumarchaeota L Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules radA - - ko:K04483 - - - - ko00000,ko03400 - - - HHH_5,Rad51 k59_360881_1 105154.Q9MBU6_9VIRU 3.05e-72 234.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_228692_1 78245.Xaut_4480 5.7e-09 62.8 COG4675@1|root,COG4675@2|Bacteria,1PE25@1224|Proteobacteria,2V8UM@28211|Alphaproteobacteria,3F1UP@335928|Xanthobacteraceae 28211|Alphaproteobacteria S tail collar domain protein - - - - - - - - - - - - - k59_180048_2 1463841.JOIR01000001_gene7024 3.8e-27 113.0 COG0209@1|root,COG0209@2|Bacteria,2IC1H@201174|Actinobacteria 201174|Actinobacteria F Ribonucleotide reductase, barrel domain - - - - - - - - - - - - Ribonuc_red_lgC k59_203762_1 1283284.AZUK01000001_gene2628 2.62e-54 184.0 COG3723@1|root,COG3723@2|Bacteria,1R6DB@1224|Proteobacteria,1RZZ3@1236|Gammaproteobacteria 1236|Gammaproteobacteria L COG3723 Recombinational DNA repair protein (RecE pathway) recT GO:0000724,GO:0000725,GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0018130,GO:0019438,GO:0032392,GO:0032508,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043150,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_188522_1 10753.B7SSM8_BPNF 6.3e-20 96.7 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNI0@10744|Podoviridae 10744|Podoviridae S viral capsid - GO:0005575,GO:0019012,GO:0019028,GO:0019030,GO:0039617,GO:0044423,GO:0046729 - - - - - - - - - - - k59_373448_1 991905.SL003B_3973 1.65e-20 95.9 COG5283@1|root,COG5283@2|Bacteria,1NFKU@1224|Proteobacteria,2U36H@28211|Alphaproteobacteria 28211|Alphaproteobacteria D tail tape measure protein - - - - - - - - - - - - PhageMin_Tail k59_325822_1 1150626.PHAMO_80087 2.98e-15 82.8 COG3941@1|root,COG3941@2|Bacteria,1PHQP@1224|Proteobacteria,2V9RW@28211|Alphaproteobacteria,2JWSI@204441|Rhodospirillales 204441|Rhodospirillales S Lambda phage tail tape-measure protein (Tape_meas_lam_C) - - - - - - - - - - - - Tape_meas_lam_C k59_82396_1 1220603.L7TMV0_9CAUD 2.36e-20 97.1 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales 28883|Caudovirales S DnaB-like helicase C terminal domain - - - - - - - - - - - - - k59_337838_3 626887.J057_01665 1.82e-55 197.0 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,1RR0M@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_57904_2 1384065.JAGS01000001_gene3082 1.34e-10 67.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia,3WGP3@541000|Ruminococcaceae 186801|Clostridia L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity - - 3.1.11.5 ko:K01144,ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,UvrD_C_2,Viral_helicase1 k59_385346_1 2003327.CAPSD_BPCHP 2.06e-40 152.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_167090_1 1158150.KB906242_gene227 2.69e-56 195.0 28IA2@1|root,2Z8CQ@2|Bacteria,1PQM2@1224|Proteobacteria,1SN3W@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_302694_12 1121271.AUCM01000005_gene721 8.05e-18 82.0 COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria 28211|Alphaproteobacteria F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase k59_204704_1 1234888.K0A2J2_9VIRU 8.57e-29 114.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_374441_1 397287.C807_04003 4.28e-07 56.6 COG2887@1|root,COG2887@2|Bacteria,1TPIC@1239|Firmicutes,247TB@186801|Clostridia,27IAF@186928|unclassified Lachnospiraceae 186801|Clostridia L Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_119099_1 1692244.A0A0K1RLR5_9CIRC 8.04e-14 70.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_119099_3 1506572.A0A097ZPG0_9CIRC 3.11e-22 99.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_277424_2 49964.Q94MS5_9CAUD 4.21e-50 174.0 4QG38@10239|Viruses,4QY33@35237|dsDNA viruses no RNA stage,4QQVI@28883|Caudovirales,4QNWM@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_83419_2 1089547.KB913013_gene167 0.000394 44.3 COG5362@1|root,COG5362@2|Bacteria,4PMSS@976|Bacteroidetes,47UCE@768503|Cytophagia 976|Bacteroidetes S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_10011_1 485913.Krac_10127 2.2e-16 83.6 COG1061@1|root,COG1061@2|Bacteria,2G94X@200795|Chloroflexi 2|Bacteria L COGs COG1061 DNA or RNA helicase of superfamily II - - - - - - - - - - - - Helicase_C,ResIII,UPF0547 k59_107463_1 1282361.ABAC402_00735 4.9e-162 469.0 COG2304@1|root,COG2304@2|Bacteria,1QW8J@1224|Proteobacteria,2U1R3@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Trove domain-containing protein - - - - - - - - - - - - TROVE k59_204716_2 1336243.JAEA01000002_gene2639 5.79e-05 52.4 2ES2P@1|root,33JMP@2|Bacteria,1NGYH@1224|Proteobacteria,2UMK8@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_314238_1 1304877.KI519399_gene4996 1.53e-35 144.0 COG0454@1|root,COG0827@1|root,COG1203@1|root,COG0456@2|Bacteria,COG0827@2|Bacteria,COG1203@2|Bacteria,1QZ6D@1224|Proteobacteria,2U5JW@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA restriction-modification system - - - - - - - - - - - - AAA_34 k59_157523_1 1304878.AUGD01000002_gene1833 6.43e-14 74.3 2DZ82@1|root,32V6V@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Tube k59_241828_1 1618248.A0A0C5IB82_9CIRC 3.95e-16 79.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_315097_1 526118.D1FNQ5_9CAUD 1.76e-32 132.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_157527_1 196490.AUEZ01000034_gene2665 1.17e-47 167.0 2DWD7@1|root,33ZRR@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_120063_1 1234879.K0A1L0_9CIRC 3.08e-15 77.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_157528_1 485913.Krac_6813 7.97e-26 105.0 COG0290@1|root,COG0290@2|Bacteria,2G6N2@200795|Chloroflexi 200795|Chloroflexi J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC - - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N k59_72280_1 105154.Q9MBU3_9VIRU 1.17e-12 71.6 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_72280_2 105154.Q9MBU6_9VIRU 2.75e-94 293.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_47859_1 1234888.K0A2J2_9VIRU 5.1e-47 167.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_108537_2 1121022.ABENE_05670 5.28e-13 70.9 COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,2TT03@28211|Alphaproteobacteria,2KFU8@204458|Caulobacterales 204458|Caulobacterales L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA - - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k59_72408_1 1121100.JCM6294_535 1.98e-39 147.0 COG0553@1|root,COG0863@1|root,COG0553@2|Bacteria,COG0863@2|Bacteria,4NHHF@976|Bacteroidetes,2FRI5@200643|Bacteroidia,4ATW7@815|Bacteroidaceae 976|Bacteroidetes KL DNA methylase - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_190000_2 1158150.KB906242_gene234 6.87e-84 254.0 2EMTV@1|root,33FG7@2|Bacteria 2|Bacteria S Gene 88 protein - - - - - - - - - - - - GP88 k59_278487_1 330214.NIDE0434 1.2e-06 52.4 COG1686@1|root,COG1686@2|Bacteria,3J179@40117|Nitrospirae 40117|Nitrospirae M Belongs to the peptidase S11 family - - 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Peptidase_S11 k59_265896_2 1618247.A0A0C5IMK7_9CIRC 1.76e-07 57.4 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_190539_2 504346.B5WZS6_BPPAJ 2.01e-64 203.0 4QEAQ@10239|Viruses,4QVWS@35237|dsDNA viruses no RNA stage,4QQWE@28883|Caudovirales 28883|Caudovirales S transferase activity, transferring glycosyl groups - - - - - - - - - - - - - k59_376310_1 1089439.KB902270_gene2574 1.13e-11 71.6 COG4379@1|root,COG4379@2|Bacteria,1MX68@1224|Proteobacteria 1224|Proteobacteria S Tail protein gpP - - - - - - - - - - - Phage_GPD k59_11952_1 1379725.S5TMY9_9CIRC 1.56e-18 85.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_255001_1 1234888.K0A2J2_9VIRU 2.1e-131 394.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_255012_1 1385511.N783_02635 1.77e-06 55.8 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,2Y9TG@289201|Pontibacillus 91061|Bacilli L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A k59_206528_2 1076630.S5VWN6_9CAUD 6.29e-20 91.3 4QG6Q@10239|Viruses,4QZ5J@35237|dsDNA viruses no RNA stage,4QRA8@28883|Caudovirales,4QMRC@10699|Siphoviridae 10699|Siphoviridae S PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - - k59_158731_3 913183.E5RV06_9CAUD 4.94e-38 134.0 4QASP@10239|Viruses,4QVR8@35237|dsDNA viruses no RNA stage,4QR4Z@28883|Caudovirales,4QNQ0@10744|Podoviridae 10744|Podoviridae S deoxyribonuclease IV (phage-T4-induced) activity - - - - - - - - - - - - - k59_146493_1 1144310.PMI07_002360 0.000429 48.5 2DPZ1@1|root,3340X@2|Bacteria,1R2EE@1224|Proteobacteria,2TZIB@28211|Alphaproteobacteria,4BP2Q@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_37054_3 1121861.KB899916_gene1642 4.89e-16 75.5 2DNV9@1|root,32ZB3@2|Bacteria,1R2IQ@1224|Proteobacteria,2TZKJ@28211|Alphaproteobacteria,2JZ35@204441|Rhodospirillales 2|Bacteria - - - - - - - - - - - - - - - k59_97813_1 1618248.A0A0C5IB82_9CIRC 1.66e-20 95.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_24912_1 1234888.K0A2J2_9VIRU 2.39e-42 152.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_292314_1 1552758.NC00_01260 1.85e-29 122.0 COG3566@1|root,COG3566@2|Bacteria,1REIQ@1224|Proteobacteria,1SZWW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2213) - - - - - - - - - - - - DUF2213 k59_207329_1 707757.D5JFT2_9CAUD 5.54e-19 92.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QI82@10662|Myoviridae 10662|Myoviridae S virus tail, fiber - - - - - - - - - - - - - k59_207329_7 520999.PROVALCAL_01154 2.76e-26 115.0 COG0582@1|root,COG0582@2|Bacteria,1MVZB@1224|Proteobacteria,1RP4Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - ko:K14059 - - - - ko00000 - - - Arm-DNA-bind_2,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase k59_207329_11 1415780.JPOG01000001_gene1787 2.57e-15 79.3 COG3756@1|root,COG3756@2|Bacteria,1N7G4@1224|Proteobacteria,1SEVU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - DUF1376 k59_207329_14 546266.NEIMUCOT_06655 5.06e-25 103.0 COG3646@1|root,COG3646@2|Bacteria,1N86G@1224|Proteobacteria,2VYP0@28216|Betaproteobacteria 28216|Betaproteobacteria S Phage regulatory protein, Rha family - - - - - - - - - - - - ORF11CD3,Phage_pRha k59_207329_17 1279038.KB907345_gene3468 4.98e-20 86.7 COG4570@1|root,COG4570@2|Bacteria,1N32D@1224|Proteobacteria,2UG2K@28211|Alphaproteobacteria,2JU2K@204441|Rhodospirillales 204441|Rhodospirillales L Holliday junction resolvase - - - - - - - - - - - - RusA k59_146507_1 1502724.FF80_03327 3.73e-07 50.8 COG3756@1|root,COG3756@2|Bacteria,1NHNH@1224|Proteobacteria,2VGAF@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF1376) - - - - - - - - - - - - DUF1376 k59_255735_1 926564.KI911577_gene452 2.58e-48 172.0 COG0749@1|root,COG0749@2|Bacteria,2I975@201174|Actinobacteria 201174|Actinobacteria L COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_pol_A,DNA_pol_A_exo1 k59_12690_12 1265310.CCBD010000081_gene5127 8.47e-06 56.6 COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,2IBWG@201174|Actinobacteria,236HX@1762|Mycobacteriaceae 201174|Actinobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_1 k59_147123_1 1385658.U5KPZ6_9VIRU 2.31e-71 234.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_341308_3 1609634.A0A0C5AFT2_9VIRU 2.22e-103 312.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_159314_1 1385658.U5KPZ6_9VIRU 6.69e-30 118.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_159314_5 1165094.RINTHH_3920 7.96e-65 213.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_159314_8 1385658.U5KPZ6_9VIRU 3.47e-161 474.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_329403_1 1499967.BAYZ01000197_gene3053 1.2e-38 146.0 COG4383@1|root,COG4383@2|Bacteria 2|Bacteria L Mu-like prophage protein gp29 - - - - - - - - - - - - DUF935 k59_232108_1 145579.CAPSD_BPPHM 2.61e-43 166.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_49962_16 314265.R2601_24040 0.000119 47.8 2CC5E@1|root,3345H@2|Bacteria,1N69Q@1224|Proteobacteria,2UF2K@28211|Alphaproteobacteria 28211|Alphaproteobacteria S IMG reference gene - - - - - - - - - - - - - k59_49962_19 1125863.JAFN01000001_gene3562 6.73e-72 271.0 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,42QDD@68525|delta/epsilon subdivisions,2WIU9@28221|Deltaproteobacteria 28221|Deltaproteobacteria U Phage-related protein, tail - - - - - - - - - - - - Phage-tail_3 k59_317349_2 1609634.A0A0C5ANA6_9VIRU 5.21e-09 61.2 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_159318_2 375286.mma_2202 5.95e-16 77.4 28NGF@1|root,2Z9HT@2|Bacteria,1R9QF@1224|Proteobacteria,2VPSU@28216|Betaproteobacteria,47599@75682|Oxalobacteraceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_122952_1 1205680.CAKO01000001_gene3133 1.54e-24 98.2 COG3409@1|root,COG3409@2|Bacteria,1NAI5@1224|Proteobacteria 1224|Proteobacteria M N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2,PG_binding_1 k59_378036_2 1234888.K0A2J2_9VIRU 7.84e-99 306.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_159321_1 1618248.A0A0C5IB82_9CIRC 2.25e-21 94.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_353879_1 1692244.A0A0K1RLR5_9CIRC 1.66e-64 206.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_13382_3 65071.PYU1_T007658 3.81e-14 77.0 COG0500@1|root,2S9CR@2759|Eukaryota,1MI4H@121069|Pythiales 121069|Pythiales Q methyltransferase activity - - - - - - - - - - - - - k59_208737_1 864069.MicloDRAFT_00064220 1.22e-36 131.0 COG0863@1|root,COG0863@2|Bacteria,1R7RR@1224|Proteobacteria,2TS8Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase k59_208737_2 10704.B4UTY5_BP163 1.18e-20 89.7 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_123583_1 743722.Sph21_3239 3.69e-05 54.3 COG0438@1|root,COG0438@2|Bacteria,4NIWP@976|Bacteroidetes,1IR4B@117747|Sphingobacteriia 976|Bacteroidetes M PFAM Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k59_366124_1 1430440.MGMSRv2_3490 5.26e-23 95.1 COG2227@1|root,COG2227@2|Bacteria,1QYVF@1224|Proteobacteria,2TZ70@28211|Alphaproteobacteria 28211|Alphaproteobacteria H 3-demethylubiquinone-9 3-O-methyltransferase activity - - - - - - - - - - - - - k59_257004_1 105154.Q9MBU6_9VIRU 8.09e-69 225.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_305787_2 1609634.A0A0C5ANA6_9VIRU 7.74e-21 93.6 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_171977_1 756272.Plabr_0241 4.42e-49 168.0 COG0639@1|root,COG0639@2|Bacteria 2|Bacteria T phosphoprotein phosphatase activity - - 3.1.3.16 ko:K07313 - - - - ko00000,ko01000 - - - Metallophos,Metallophos_2 k59_74871_2 1618237.A0A0C5IMG6_9CIRC 1.62e-28 120.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_257007_2 1173021.ALWA01000038_gene1773 4.25e-05 48.9 COG0358@1|root,COG0358@2|Bacteria,1G0TV@1117|Cyanobacteria 1117|Cyanobacteria L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,Toprim_2,Toprim_N,zf-CHC2 k59_305791_1 1120963.KB894511_gene2529 2.01e-56 188.0 COG0175@1|root,COG0175@2|Bacteria,1QF53@1224|Proteobacteria,1RN3J@1236|Gammaproteobacteria 1236|Gammaproteobacteria EH PFAM phosphoadenosine - - - - - - - - - - - - PAPS_reduct k59_305791_2 195105.CN97_02810 2.76e-05 48.1 2CJKM@1|root,314EI@2|Bacteria,1RGVN@1224|Proteobacteria,2UBK7@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_269130_1 313596.RB2501_01415 4.27e-57 194.0 COG1061@1|root,COG2093@1|root,COG1061@2|Bacteria,COG2093@2|Bacteria,4NECV@976|Bacteroidetes,1HXAD@117743|Flavobacteriia 976|Bacteroidetes L Domain of unknown function (DUF3427) - - - - - - - - - - - - Helicase_C,ResIII k59_354403_1 717785.HYPMC_1709 1.05e-26 102.0 COG0270@1|root,COG0863@1|root,COG0270@2|Bacteria,COG0863@2|Bacteria,1R5MR@1224|Proteobacteria,2U53Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_50528_2 1536769.P40081_28605 1.89e-39 145.0 COG0175@1|root,COG0175@2|Bacteria,1TZYA@1239|Firmicutes,4I97T@91061|Bacilli,27157@186822|Paenibacillaceae 91061|Bacilli EH Phosphoadenosine phosphosulfate reductase family - - - - - - - - - - - - PAPS_reduct k59_293591_6 1347392.CCEZ01000043_gene417 7.45e-18 80.9 2E3AH@1|root,32YA0@2|Bacteria,1VGN7@1239|Firmicutes,25DV7@186801|Clostridia,36UF5@31979|Clostridiaceae 186801|Clostridia S Protein of unknown function (DUF1064) - - - - - - - - - - - - DUF1064 k59_282771_1 693746.OBV_23940 0.000793 42.7 COG3728@1|root,COG3728@2|Bacteria 2|Bacteria L DNA packaging xtmA - - ko:K07474 - - - - ko00000 - - - Terminase_2 k59_282771_3 370438.PTH_2144 7.69e-13 72.4 COG0863@1|root,COG1041@1|root,COG0863@2|Bacteria,COG1041@2|Bacteria,1TRDZ@1239|Firmicutes,249ZT@186801|Clostridia,2652N@186807|Peptococcaceae 186801|Clostridia H DNA methylase - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_257583_1 436308.Nmar_1767 4.25e-05 50.4 COG0484@1|root,arCOG02846@2157|Archaea,41T1F@651137|Thaumarchaeota 651137|Thaumarchaeota O DnaJ molecular chaperone homology domain - - - - - - - - - - - - DnaJ k59_75326_1 1121441.AUCX01000001_gene2666 3.54e-98 300.0 28HXV@1|root,2Z83C@2|Bacteria,1PJBP@1224|Proteobacteria,43EA9@68525|delta/epsilon subdivisions,2X050@28221|Deltaproteobacteria,2MAJ5@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_269679_32 305900.GV64_01840 5.01e-05 53.5 COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1XI4U@135619|Oceanospirillales 135619|Oceanospirillales L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 k59_269679_33 1123256.KB907925_gene1522 1.61e-06 56.6 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1X3IJ@135614|Xanthomonadales 135614|Xanthomonadales K Belongs to the ParB family parB - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_269679_37 293826.Amet_0541 1.5e-07 58.9 COG1388@1|root,COG3409@1|root,COG1388@2|Bacteria,COG3409@2|Bacteria,1V10C@1239|Firmicutes 1239|Firmicutes M PFAM LysM domain - - - - - - - - - - - - LysM k59_173125_6 1234888.K0A2J2_9VIRU 5.26e-139 415.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_39065_1 1609634.A0A0C5AFV4_9VIRU 3.66e-79 255.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_39065_3 1385658.U5KNR1_9VIRU 4.96e-68 222.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_39065_6 105154.Q9MBU3_9VIRU 6.84e-20 90.5 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_39065_7 105154.Q9MBU6_9VIRU 3.63e-107 328.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_161087_1 1238450.VIBNISOn1_1190023 7.05e-10 65.5 2F6W9@1|root,33ZCB@2|Bacteria,1NZ0D@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_270185_2 632518.Calow_0833 4.52e-09 64.7 28JC4@1|root,2Z96S@2|Bacteria,1TS1K@1239|Firmicutes,249Q6@186801|Clostridia 186801|Clostridia S P22 coat protein-protein 5 domain protein - - - - - - - - - - - - P22_CoatProtein k59_3254_3 105154.Q9MBU3_9VIRU 3.19e-05 51.2 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_3254_4 105154.Q9MBU6_9VIRU 2.36e-80 257.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_294693_1 1692253.A0A0K1RLM4_9CIRC 7.41e-29 115.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_379686_1 1123269.NX02_21990 1.45e-47 162.0 COG0863@1|root,COG0863@2|Bacteria,1NQ2A@1224|Proteobacteria,2UJ12@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase k59_148686_3 1122997.AUDD01000007_gene814 1.63e-11 65.9 COG0863@1|root,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_319298_2 445970.ALIPUT_01194 9.38e-06 50.4 2E8S0@1|root,3332X@2|Bacteria,4NWIA@976|Bacteroidetes,2FUQI@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_3256_1 1280692.AUJL01000020_gene1850 0.000267 49.3 COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia,36FVZ@31979|Clostridiaceae 186801|Clostridia D Peptidase, M23 - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 k59_222120_11 1115632.JAFW01000001_gene3445 6.06e-23 99.0 arCOG05626@1|root,2Z9D9@2|Bacteria,2IIAB@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_331954_1 1408324.JNJK01000006_gene1391 0.000479 48.9 COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia,27J2F@186928|unclassified Lachnospiraceae 186801|Clostridia S Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_173772_1 1234888.K0A2J2_9VIRU 1.35e-92 287.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_64669_1 596151.DesfrDRAFT_3233 1.93e-25 108.0 COG1216@1|root,COG1216@2|Bacteria,1R554@1224|Proteobacteria,435KX@68525|delta/epsilon subdivisions,2WZZC@28221|Deltaproteobacteria,2M92V@213115|Desulfovibrionales 28221|Deltaproteobacteria S Glycosyl transferase, family 2 - - - - - - - - - - - - - k59_270771_2 1123502.AQXD01000002_gene251 5.24e-15 75.5 COG0279@1|root,COG0279@2|Bacteria,1NVIE@1224|Proteobacteria,1RP6M@1236|Gammaproteobacteria,1X6Q4@135614|Xanthomonadales 135614|Xanthomonadales G SIS domain - - - - - - - - - - - - SIS_2 k59_173776_1 1121378.KB899726_gene4386 1.83e-34 138.0 COG0553@1|root,COG0553@2|Bacteria,1WNE4@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair - - - - - - - - - - - - Helicase_C,SNF2_N k59_161773_2 1226994.AMZB01000137_gene5411 4.85e-21 89.0 2EIQ2@1|root,33CFI@2|Bacteria,1NHAI@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_307548_1 926564.KI911577_gene452 6.92e-67 220.0 COG0749@1|root,COG0749@2|Bacteria,2I975@201174|Actinobacteria 201174|Actinobacteria L COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_pol_A,DNA_pol_A_exo1 k59_355990_2 484018.BACPLE_00805 0.000177 51.2 2EVUA@1|root,33P81@2|Bacteria,4P82D@976|Bacteroidetes,2FV68@200643|Bacteroidia,4AU6A@815|Bacteroidaceae 976|Bacteroidetes - - - - - - - - - - - - - - - k59_343762_1 1574422.A0A0A1ENW9_9CIRC 3.39e-13 71.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_112870_1 1089447.RHAA1_05308 1.75e-24 107.0 COG5281@1|root,COG5281@2|Bacteria,1MX2R@1224|Proteobacteria,1S3MM@1236|Gammaproteobacteria,1Y73U@135625|Pasteurellales 135625|Pasteurellales S tail length tape measure protein - - - - - - - - - - - - - k59_149367_2 1203606.HMPREF1526_01800 3.82e-17 85.5 COG0358@1|root,COG2771@1|root,COG3598@1|root,COG0358@2|Bacteria,COG2771@2|Bacteria,COG3598@2|Bacteria,1TQKP@1239|Firmicutes,247WJ@186801|Clostridia,36FQT@31979|Clostridiaceae 186801|Clostridia L Protein of unknown function (DUF3991) - - - - - - - - - - - - AAA_25,DUF3991,Toprim_2 k59_295352_1 1165094.RINTHH_3920 3.52e-68 220.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_295352_5 1986029.Q9MBM7_9VIRU 6.77e-20 90.9 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_198662_1 1156937.MFUM_720047 9.07e-32 120.0 COG0279@1|root,COG0279@2|Bacteria,46SXU@74201|Verrucomicrobia,37GT1@326457|unclassified Verrucomicrobia 74201|Verrucomicrobia G SIS domain gmhA - 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 - - - SIS_2 k59_113517_1 645512.GCWU000246_00694 3.07e-25 108.0 COG4626@1|root,COG4626@2|Bacteria,3TC4C@508458|Synergistetes 508458|Synergistetes S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_77164_1 198214.SF1372 2.15e-31 122.0 COG0468@1|root,COG0468@2|Bacteria,1PK58@1224|Proteobacteria,1RYHG@1236|Gammaproteobacteria 1236|Gammaproteobacteria L AAA domain - - - - - - - - - - - - AAA_24 k59_77164_2 1469948.JPNB01000001_gene662 3.74e-05 51.6 COG1475@1|root,COG1475@2|Bacteria,1V2SD@1239|Firmicutes,24GNZ@186801|Clostridia,36JZG@31979|Clostridiaceae 186801|Clostridia K Psort location Cytoplasmic, score - - - - - - - - - - - - - k59_381017_2 1417599.U6C6Y4_9CAUD 4.47e-53 183.0 4QF87@10239|Viruses,4QYZ4@35237|dsDNA viruses no RNA stage,4QPVW@28883|Caudovirales,4QNV3@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_381017_3 1417599.U6C6F9_9CAUD 4.2e-41 147.0 4QBD3@10239|Viruses,4QXFU@35237|dsDNA viruses no RNA stage,4QQ7Z@28883|Caudovirales,4QNJ0@10744|Podoviridae 10744|Podoviridae S P22 coat protein - gene protein 5 - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0009987,GO:0016032,GO:0016043,GO:0019012,GO:0019028,GO:0019030,GO:0019058,GO:0019068,GO:0019069,GO:0019075,GO:0022607,GO:0039620,GO:0042802,GO:0042803,GO:0044085,GO:0044403,GO:0044419,GO:0044423,GO:0046729,GO:0046797,GO:0046983,GO:0051704,GO:0071840 - - - - - - - - - - - k59_356683_2 1379719.S5TMX6_9CIRC 1.6e-27 110.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_174661_2 1609634.A0A0C5ANA6_9VIRU 1.67e-12 73.2 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_77165_1 272630.MexAM1_META1p3978 6.03e-33 124.0 COG4643@1|root,COG4643@2|Bacteria,1MW9E@1224|Proteobacteria,2TS3B@28211|Alphaproteobacteria,1JWRA@119045|Methylobacteriaceae 28211|Alphaproteobacteria S Toprim domain - - - ko:K06919 - - - - ko00000 - - - Toprim_3,zf-CHC2 k59_65337_1 1609634.A0A0C5AFV4_9VIRU 1.55e-84 267.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_368510_1 145579.CAPSD_BPPHM 2.05e-91 294.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_40435_1 1165094.RINTHH_3920 6.81e-29 112.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_271485_1 1112217.PPL19_05400 5.54e-64 210.0 COG0582@1|root,COG0582@2|Bacteria,1QB64@1224|Proteobacteria,1RY8S@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_1,Phage_int_SAM_4,Phage_integrase k59_126226_2 500637.PROVRUST_06409 2.28e-50 175.0 COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,1RPM4@1236|Gammaproteobacteria,3Z9II@586|Providencia 1236|Gammaproteobacteria H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family dcm GO:0003674,GO:0003824,GO:0003886,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009008,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0032776,GO:0034641,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044728,GO:0046483,GO:0071704,GO:0090116,GO:0090304,GO:0140097,GO:1901360 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_259410_2 1692256.A0A0K1RL85_9CIRC 5.17e-16 77.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_53080_1 1538804.A0A088F7W8_9CAUD 2.52e-09 58.2 4QAR1@10239|Viruses,4QPJE@28883|Caudovirales 28883|Caudovirales S ATPase activity - - - - - - - - - - - - - k59_235187_1 1340493.JNIF01000004_gene5 2.4e-38 138.0 COG1961@1|root,COG1961@2|Bacteria 2|Bacteria L recombinase activity - - - - - - - - - - - - Recombinase,Resolvase k59_40572_1 742767.HMPREF9456_03236 4.71e-36 135.0 COG1783@1|root,COG1783@2|Bacteria,4NHPB@976|Bacteroidetes,2FR95@200643|Bacteroidia,22WQM@171551|Porphyromonadaceae 976|Bacteroidetes S Terminase RNAseH like domain - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_114193_2 1121459.AQXE01000001_gene2774 8.32e-140 441.0 COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria,42YXG@68525|delta/epsilon subdivisions,2WU1V@28221|Deltaproteobacteria,2M9ED@213115|Desulfovibrionales 28221|Deltaproteobacteria K DNA-dependent RNA polymerase - - - - - - - - - - - - RNA_pol,RPOL_N k59_78071_1 663278.Ethha_0102 6.03e-11 68.2 COG3941@1|root,COG5412@1|root,COG3941@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia,3WJR8@541000|Ruminococcaceae 186801|Clostridia D Phage tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail k59_53733_3 1234888.K0A2R8_9VIRU 1.05e-29 120.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_53733_5 1234888.K0A2J2_9VIRU 1.9e-128 389.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_369263_1 1609634.A0A0C5AFV4_9VIRU 1.61e-36 140.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_16322_3 1122614.JHZF01000011_gene1718 5.66e-17 78.2 2C7JB@1|root,2ZXVG@2|Bacteria,1P7GB@1224|Proteobacteria,2UYPK@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_260032_1 1042209.HK44_029960 2.41e-16 82.8 2D1GK@1|root,32TAP@2|Bacteria,1QV4T@1224|Proteobacteria,1SKJY@1236|Gammaproteobacteria 1236|Gammaproteobacteria L C-5 cytosine-specific DNA methylase - - - - - - - - - - - - DNA_methylase k59_5383_1 866536.Belba_2525 0.000904 45.1 COG1216@1|root,COG1216@2|Bacteria,4NXEZ@976|Bacteroidetes 976|Bacteroidetes S Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 k59_224252_2 1051675.G0YQC7_9CAUD 2.26e-15 75.1 4QAR1@10239|Viruses,4QUNA@35237|dsDNA viruses no RNA stage,4QPJE@28883|Caudovirales,4QNDS@10744|Podoviridae 10744|Podoviridae S ATPase activity - - - - - - - - - - - - - k59_296869_1 1029823.AFIE01000007_gene1883 6.41e-36 149.0 29KX8@1|root,307UQ@2|Bacteria,1RK1N@1224|Proteobacteria,1SNEN@1236|Gammaproteobacteria,3NJMI@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_212307_1 202956.BBNL01000066_gene214 1.57e-30 129.0 2D784@1|root,32TNH@2|Bacteria,1N098@1224|Proteobacteria,1SDM3@1236|Gammaproteobacteria,3NNDQ@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_41381_1 1692256.A0A0K1RL85_9CIRC 1.07e-27 109.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_309112_1 73044.JNXP01000021_gene2564 6.58e-09 63.9 2APGU@1|root,31EJR@2|Bacteria,2IJ12@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_334188_1 1385658.U5KNR1_9VIRU 4.24e-55 184.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_78862_1 1385658.U5KPZ6_9VIRU 3.82e-115 349.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_91448_1 1430440.MGMSRv2_1304 9.91e-45 157.0 COG0535@1|root,COG0535@2|Bacteria,1N5G8@1224|Proteobacteria,2VB0H@28211|Alphaproteobacteria,2JVSF@204441|Rhodospirillales 204441|Rhodospirillales S Iron-sulfur cluster-binding domain - - - - - - - - - - - - Radical_SAM,SPASM k59_248821_1 511.JT27_15735 5.17e-10 61.6 COG0740@1|root,COG0740@2|Bacteria,1MUQ9@1224|Proteobacteria,2VMZZ@28216|Betaproteobacteria,3T3QV@506|Alcaligenaceae 28216|Betaproteobacteria OU Clp protease - - - - - - - - - - - - CLP_protease k59_309856_1 292414.TM1040_1564 0.000186 48.9 COG1943@1|root,COG1943@2|Bacteria,1P8IT@1224|Proteobacteria,2TRKV@28211|Alphaproteobacteria,4NBUY@97050|Ruegeria 28211|Alphaproteobacteria L Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_2 k59_225116_2 1320556.AVBP01000003_gene3982 5.14e-11 68.2 COG1196@1|root,COG1196@2|Bacteria,1MU81@1224|Proteobacteria,2TZCH@28211|Alphaproteobacteria 28211|Alphaproteobacteria D tail length tape measure - - - - - - - - - - - - - k59_30562_2 1260356.D920_01718 4.39e-19 86.3 2DR9Y@1|root,33AUY@2|Bacteria,1VP6K@1239|Firmicutes,4IRHH@91061|Bacilli 91061|Bacilli L HNH endonuclease - - - - - - - - - - - - HNH_3,NUMOD4 k59_358032_1 1500301.JQMF01000006_gene1773 2.58e-35 138.0 COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria,2U1JR@28211|Alphaproteobacteria,4BC0X@82115|Rhizobiaceae 28211|Alphaproteobacteria K DNA-directed RNA polymerase N-terminal - - - - - - - - - - - - RNA_pol,RPOL_N k59_225120_2 1120977.JHUX01000003_gene853 1.11e-70 229.0 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,1RQFD@1236|Gammaproteobacteria,3NJR9@468|Moraxellaceae 1236|Gammaproteobacteria S Terminase RNAseH like domain - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_186213_1 1788449.A0A190WHL0_9CIRC 4.22e-18 81.3 4QBFZ@10239|Viruses,4QUKU@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_186213_2 1618240.A0A0C5IMJ1_9CIRC 2.75e-70 228.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_78868_1 643648.Slip_1825 1.18e-65 214.0 COG0338@1|root,COG0338@2|Bacteria,1UBIY@1239|Firmicutes,24D2Y@186801|Clostridia 186801|Clostridia L D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_358036_1 1268068.PG5_00610 2e-17 85.5 COG3723@1|root,COG3723@2|Bacteria,1R6DB@1224|Proteobacteria,1RZZ3@1236|Gammaproteobacteria 1236|Gammaproteobacteria L COG3723 Recombinational DNA repair protein (RecE pathway) recT GO:0000724,GO:0000725,GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0018130,GO:0019438,GO:0032392,GO:0032508,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043150,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_186216_1 1475143.W8SNN0_9CIRC 2.99e-13 75.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_346303_3 443152.MDG893_20574 1.2e-35 125.0 2CHRA@1|root,32S6D@2|Bacteria,1MZ8I@1224|Proteobacteria,1SHSQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage tail assembly chaperone, TAC - - - - - - - - - - - - Phage_TAC_13 k59_6265_1 1692244.A0A0K1RLR5_9CIRC 3.18e-33 127.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_6265_2 1379725.S5TMY9_9CIRC 3.2e-16 80.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_346304_1 156889.Mmc1_1716 3.96e-12 71.2 28NGF@1|root,2ZBII@2|Bacteria,1R9KY@1224|Proteobacteria,2U1P7@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_92578_1 1234888.K0A2J2_9VIRU 4.83e-37 140.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_128704_1 1502851.FG93_04315 1.73e-22 102.0 COG3170@1|root,COG3170@2|Bacteria,1Q45C@1224|Proteobacteria,2U08F@28211|Alphaproteobacteria 28211|Alphaproteobacteria NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - k59_140610_1 77856.REP_BFDV 1.2e-19 89.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_55408_1 1121940.AUDZ01000013_gene529 2.41e-25 100.0 COG0358@1|root,COG0358@2|Bacteria,1N364@1224|Proteobacteria,1SDEX@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA primase - - - - - - - - - - - - zf-CHC2 k59_31451_2 880071.Fleli_2226 1.22e-07 58.5 COG0270@1|root,COG0270@2|Bacteria,4NG9A@976|Bacteroidetes,47MCJ@768503|Cytophagia 976|Bacteroidetes H PFAM C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558,ko:K17398 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_7104_1 886293.Sinac_5882 5.35e-101 306.0 COG1089@1|root,COG1089@2|Bacteria,2IWZ4@203682|Planctomycetes 203682|Planctomycetes M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose gmd - 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd k59_7104_2 865937.Gilli_1074 4.75e-05 46.2 COG0451@1|root,COG0451@2|Bacteria,4NDV4@976|Bacteroidetes,1HYF4@117743|Flavobacteriia,2P77G@244698|Gillisia 976|Bacteroidetes GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction fcl - 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R05692 RC01014 ko00000,ko00001,ko01000 - - - Epimerase k59_165022_1 1385658.U5KNR1_9VIRU 3.08e-25 105.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_359024_3 1123269.NX02_21990 1.29e-86 270.0 COG0863@1|root,COG0863@2|Bacteria,1NQ2A@1224|Proteobacteria,2UJ12@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase k59_359024_4 1192868.CAIU01000008_gene938 1.65e-121 369.0 COG0553@1|root,COG0553@2|Bacteria,1R7CK@1224|Proteobacteria,2U228@28211|Alphaproteobacteria,43I7K@69277|Phyllobacteriaceae 28211|Alphaproteobacteria KL DEAD-like helicases superfamily - - - - - - - - - - - - Helicase_C,N6_N4_Mtase k59_310922_1 1122951.ATUE01000006_gene1033 6.66e-20 90.9 2EJXI@1|root,33DN6@2|Bacteria,1NKIP@1224|Proteobacteria,1SRVY@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_335319_1 1207063.P24_17192 2.56e-113 344.0 COG4653@1|root,COG4653@2|Bacteria,1MWU1@1224|Proteobacteria,2TSSY@28211|Alphaproteobacteria,2JVTQ@204441|Rhodospirillales 204441|Rhodospirillales S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_43331_3 1446473.JHWH01000040_gene3511 6.45e-15 75.9 COG0827@1|root,COG0827@2|Bacteria,1NRTB@1224|Proteobacteria,2UPPT@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3,HTH_31 k59_227326_1 1211814.CAPG01000027_gene1326 1.18e-07 57.0 COG5301@1|root,COG5301@2|Bacteria,1VEZ9@1239|Firmicutes,4HNUH@91061|Bacilli 91061|Bacilli G cellulose 1,4-beta-cellobiosidase activity - - - - - - - - - - - - - k59_8026_2 1036616.G1DUU3_9CAUD 1.26e-22 90.5 4QCCA@10239|Viruses,4QY28@35237|dsDNA viruses no RNA stage,4QU0Q@28883|Caudovirales,4QNA0@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_8026_3 1449048.JQKU01000001_gene2189 5.42e-12 70.9 COG1652@1|root,COG1652@2|Bacteria,2GK68@201174|Actinobacteria,232DU@1762|Mycobacteriaceae 201174|Actinobacteria S Transglycosylase-like domain rpfA GO:0005575,GO:0005576,GO:0008150,GO:0009892,GO:0010468,GO:0010605,GO:0010629,GO:0019222,GO:0040008,GO:0040009,GO:0040010,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0060255,GO:0065007 - ko:K21687 - - - - ko00000 - GH23 - DUF3235,Transglycosylas k59_44419_2 879628.E1A1F3_9CAUD 3e-09 60.5 4QAJ5@10239|Viruses,4QUS9@35237|dsDNA viruses no RNA stage,4QPY5@28883|Caudovirales,4QHUT@10662|Myoviridae 10662|Myoviridae S Major capsid protein Gp23 - GO:0005575,GO:0019012,GO:0019028,GO:0044423 - - - - - - - - - - - k59_359951_1 1235835.C814_01178 7.01e-29 120.0 COG5525@1|root,COG5525@2|Bacteria,1TQBY@1239|Firmicutes,248DP@186801|Clostridia,3WGMP@541000|Ruminococcaceae 186801|Clostridia S Phage terminase large subunit (GpA) - - - - - - - - - - - - Terminase_GpA k59_93887_1 742726.HMPREF9448_01213 1.64e-17 82.0 COG0860@1|root,COG0860@2|Bacteria,4NR00@976|Bacteroidetes,2FQBB@200643|Bacteroidia,2312Q@171551|Porphyromonadaceae 976|Bacteroidetes M N-acetylmuramoyl-L-alanine amidase - - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3 k59_311999_1 1502852.FG94_04990 2.34e-27 117.0 COG3170@1|root,COG3170@2|Bacteria,1N4R0@1224|Proteobacteria,2VPR6@28216|Betaproteobacteria 28216|Betaproteobacteria NU Tfp pilus assembly protein FimV - - - - - - - - - - - - P22_portal k59_69126_2 691966.D4P725_9CAUD 3.26e-38 140.0 4QAJ3@10239|Viruses,4QVQ1@35237|dsDNA viruses no RNA stage,4QPYB@28883|Caudovirales,4QKSJ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_275414_1 1123263.AUKY01000096_gene1823 2.61e-54 180.0 COG0827@1|root,COG0827@2|Bacteria,1UZYQ@1239|Firmicutes 1239|Firmicutes L DNA restriction-modification system - - - - - - - - - - - - - k59_239604_2 411474.COPEUT_01529 1.83e-23 105.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia 186801|Clostridia L DNA polymerase III, alpha subunit dnaE - 2.7.7.7 ko:K02337,ko:K14162 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k59_349594_1 1618247.A0A0C5IMK7_9CIRC 2.3e-08 59.7 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_188389_1 1692249.A0A0K1RLN8_9CIRC 1.72e-33 126.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_360847_2 145579.CAPSD_BPPHM 3.94e-41 148.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_325616_2 929703.KE386491_gene2677 1.01e-10 63.2 COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,47QZT@768503|Cytophagia 976|Bacteroidetes L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_155295_2 1506994.JNLQ01000002_gene3180 4.02e-08 60.5 COG0438@1|root,COG2227@1|root,COG0438@2|Bacteria,COG2227@2|Bacteria,1VBYX@1239|Firmicutes 1239|Firmicutes H Methyltransferase domain - - - - - - - - - - - - Methyltransf_23 k59_155295_4 252305.OB2597_16030 1.04e-12 81.3 COG1572@1|root,COG1864@1|root,COG3209@1|root,COG3386@1|root,COG3391@1|root,COG1572@2|Bacteria,COG1864@2|Bacteria,COG3209@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,1QW4H@1224|Proteobacteria 1224|Proteobacteria M Rhs Family - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - Autotransporter,Big_3_2,Big_3_5,DUF4082,DUF4347,He_PIG k59_70159_1 1121430.JMLG01000021_gene1374 4.49e-16 84.7 COG4967@1|root,COG4967@2|Bacteria,1VKH2@1239|Firmicutes,24UHG@186801|Clostridia 186801|Clostridia NU type IV pilus modification protein PilV - - - - - - - - - - - - N_methyl k59_20006_1 716928.AJQT01000109_gene1217 6.61e-44 147.0 2FEUE@1|root,346TC@2|Bacteria,1MZPB@1224|Proteobacteria,2UC4Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_216672_1 399741.Spro_0395 1.26e-26 109.0 COG4227@1|root,COG4227@2|Bacteria,1MU8I@1224|Proteobacteria,1RNU7@1236|Gammaproteobacteria,4018J@613|Serratia 1236|Gammaproteobacteria L Domain of unknown function (DUF1738) traC - - - - - - - - - - - DUF1738,Toprim_4 k59_239729_1 665956.HMPREF1032_00634 1.68e-38 139.0 2A0KC@1|root,30NQJ@2|Bacteria,1V3K4@1239|Firmicutes,24HYK@186801|Clostridia,3WN0E@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_276402_2 335543.Sfum_2504 1.13e-13 73.2 COG1948@1|root,COG1948@2|Bacteria,1N91Q@1224|Proteobacteria,42PBQ@68525|delta/epsilon subdivisions,2WJTC@28221|Deltaproteobacteria,2MRX3@213462|Syntrophobacterales 28221|Deltaproteobacteria L ERCC4 domain - - - - - - - - - - - - ERCC4 k59_252132_1 1304878.AUGD01000009_gene6393 3.26e-15 72.4 2EMVQ@1|root,33FHY@2|Bacteria,1NNSC@1224|Proteobacteria,2UWDN@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_252132_3 266779.Meso_0243 6.55e-07 51.6 COG3179@1|root,COG3179@2|Bacteria,1R71F@1224|Proteobacteria,2UD1N@28211|Alphaproteobacteria,43MAV@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S chitinase - - - - - - - - - - - - Glyco_hydro_19 k59_95199_1 1430440.MGMSRv2_0692 4.65e-23 100.0 COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,2U64S@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_360936_1 272568.GDI3669 5.2e-84 270.0 COG1783@1|root,COG1783@2|Bacteria,1RAGC@1224|Proteobacteria,2U6JF@28211|Alphaproteobacteria,2JSIA@204441|Rhodospirillales 204441|Rhodospirillales S phage Terminase large subunit - - - - - - - - - - - - - k59_360936_2 1417296.U879_00355 4.74e-10 62.4 28JTG@1|root,2Z7PY@2|Bacteria,1QVNY@1224|Proteobacteria,2U7ED@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_83433_2 1096546.WYO_0193 2.7e-10 61.2 28JC4@1|root,2Z96S@2|Bacteria,1RI8W@1224|Proteobacteria 1224|Proteobacteria S P22 coat protein-protein 5 domain protein - - - - - - - - - - - - - k59_132383_1 1126411.I1TEL3_9CIRC 2.45e-10 63.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_229830_1 929556.Solca_0378 1.18e-11 71.6 COG0592@1|root,COG0592@2|Bacteria,4NESB@976|Bacteroidetes,1IP8C@117747|Sphingobacteriia 976|Bacteroidetes L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 k59_204727_1 883077.HMPREF9241_00161 7.75e-13 73.6 COG0749@1|root,COG0749@2|Bacteria,2IG0A@201174|Actinobacteria,4D4MC@85005|Actinomycetales 201174|Actinobacteria L DNA polymerase - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_71263_1 1385658.U5KPZ6_9VIRU 4.52e-105 323.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_350654_4 1234888.K0A2J2_9VIRU 8.89e-156 458.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_21197_2 1397527.Q670_07805 3.43e-28 107.0 COG0137@1|root,COG0137@2|Bacteria,1MYHX@1224|Proteobacteria,1S8A1@1236|Gammaproteobacteria,1XQT6@135619|Oceanospirillales 135619|Oceanospirillales E Protein of unknown function (DUF2493) - - - - - - - - - - - - DUF2493 k59_229832_2 1408433.JHXV01000015_gene1722 2.98e-72 243.0 COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,1HXQH@117743|Flavobacteriia,2PAM6@246874|Cryomorphaceae 976|Bacteroidetes J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c k59_302729_1 1618247.A0A0C5I2K0_9CIRC 6.69e-26 112.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_291272_4 1385658.U5KPZ6_9VIRU 1e-220 628.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_291272_6 1385658.U5KNR1_9VIRU 8.92e-47 165.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_168013_1 1385658.U5KPZ6_9VIRU 1.47e-135 405.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_168013_5 1986029.Q9MBM3_9VIRU 5.92e-45 159.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_326895_1 1125863.JAFN01000001_gene3549 0.000168 45.8 COG4653@1|root,COG4653@2|Bacteria,1MWMB@1224|Proteobacteria,42UPY@68525|delta/epsilon subdivisions,2WQZZ@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_326895_2 1500897.JQNA01000001_gene5816 1.67e-06 53.9 COG5511@1|root,COG5511@2|Bacteria,1MVN4@1224|Proteobacteria,2VKKT@28216|Betaproteobacteria,1K1WU@119060|Burkholderiaceae 28216|Betaproteobacteria S Phage portal protein, lambda family - - - - - - - - - - - - Phage_portal_2 k59_96476_1 1335760.ASTG01000033_gene36 1.07e-32 124.0 COG0863@1|root,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_194351_3 563192.HMPREF0179_02946 0.000104 45.8 2DNTW@1|root,32Z46@2|Bacteria,1N82R@1224|Proteobacteria,431IC@68525|delta/epsilon subdivisions,2WWYT@28221|Deltaproteobacteria,2MDJ5@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_194375_1 365659.smi_0426 2.2e-11 63.2 2DJ23@1|root,32UC6@2|Bacteria,1VA3C@1239|Firmicutes,4HM73@91061|Bacilli 91061|Bacilli S VRR-NUC domain - - - - - - - - - - - - VRR_NUC k59_194375_2 1392487.JIAD01000001_gene369 8.34e-08 61.6 COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,25V6T@186806|Eubacteriaceae 186801|Clostridia L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k59_194375_8 795666.MW7_1076 4.44e-28 119.0 COG3378@1|root,COG3378@2|Bacteria,1MV7I@1224|Proteobacteria,2VM9Y@28216|Betaproteobacteria,1K6UZ@119060|Burkholderiaceae 28216|Betaproteobacteria S D5 N terminal like - - - ko:K06919 - - - - ko00000 - - - D5_N,PriCT_2 k59_194406_1 1234888.K0A2J2_9VIRU 3.42e-80 254.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_206803_2 1475143.W8SNN0_9CIRC 5.12e-43 156.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_85284_1 641143.HMPREF9331_02209 5.62e-07 54.3 COG0507@1|root,COG0507@2|Bacteria,4NDYK@976|Bacteroidetes,1HWXU@117743|Flavobacteriia,1EQV2@1016|Capnocytophaga 976|Bacteroidetes L exodeoxyribonuclease V recD2_2 - 3.1.11.5 ko:K01144 - - - - ko00000,ko01000 - - - AAA_30,UvrD_C_2 k59_85284_3 1173762.S4TP20_9CAUD 1e-63 216.0 4QB3X@10239|Viruses,4QWKP@35237|dsDNA viruses no RNA stage,4QPEE@28883|Caudovirales,4QNCI@10744|Podoviridae 10744|Podoviridae S VWA-like domain (DUF2201) - - - - - - - - - - - - - k59_36732_1 1121396.KB893101_gene494 1.03e-12 77.4 COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,42N7D@68525|delta/epsilon subdivisions,2WKJS@28221|Deltaproteobacteria,2MPWR@213118|Desulfobacterales 28221|Deltaproteobacteria O Subtilase family - - - - - - - - - - - - Big_3_2,Big_3_3,Inhibitor_I9,Peptidase_S8 k59_274_1 691965.D4P7I3_9CAUD 2.91e-170 517.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_60995_1 1234888.K0A2J2_9VIRU 1.38e-78 255.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_364696_2 1150599.MPHLEI_07809 1.51e-32 119.0 arCOG05626@1|root,32V4D@2|Bacteria,2I38M@201174|Actinobacteria,23FBM@1762|Mycobacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_364696_5 691965.D4P7L3_9CAUD 1.32e-144 429.0 4QBH7@10239|Viruses,4QWWF@35237|dsDNA viruses no RNA stage,4QQ8R@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_376916_2 582899.Hden_1190 3.22e-13 69.3 COG1694@1|root,COG1694@2|Bacteria,1N3XF@1224|Proteobacteria,2UG4F@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Mazg nucleotide pyrophosphohydrolase - - - - - - - - - - - - - k59_275_1 90813.JQMT01000001_gene1510 1.84e-13 70.9 COG0494@1|root,COG0494@2|Bacteria,1N9TV@1224|Proteobacteria,1SG85@1236|Gammaproteobacteria 1236|Gammaproteobacteria L NUDIX domain - - - - - - - - - - - - NUDIX k59_275_3 717605.Theco_3974 2.39e-20 86.7 2E6SZ@1|root,331CZ@2|Bacteria,1VXJJ@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - k59_60998_1 545694.TREPR_1847 6.39e-17 85.9 2F2X1@1|root,33VSN@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DNA_ligase_A_C k59_231032_11 375286.mma_2769 4.54e-31 132.0 COG0616@1|root,COG0616@2|Bacteria,1QGPW@1224|Proteobacteria,2VJ0N@28216|Betaproteobacteria 28216|Betaproteobacteria OU PFAM peptidase S49 - - - - - - - - - - - - Peptidase_S49 k59_231032_12 1414739.W6ATE0_9CAUD 4.26e-108 336.0 4QHNU@10239|Viruses,4QQZH@28883|Caudovirales,4QKRG@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_231032_13 314262.MED193_12483 2.67e-09 68.9 COG5525@1|root,COG5525@2|Bacteria,1MVS3@1224|Proteobacteria,2TRW8@28211|Alphaproteobacteria,2P4BZ@2433|Roseobacter 28211|Alphaproteobacteria S Phage terminase large subunit (GpA) - - - - - - - - - - - - Terminase_GpA k59_195831_1 28152.DJ57_2245 2.6e-16 87.0 28IJ1@1|root,2Z8K0@2|Bacteria,1R5PC@1224|Proteobacteria,1S1ER@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_147328_2 1283079.M1HMA6_9CAUD 1.86e-50 181.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_268737_2 1795989.A0A140CTP4_9VIRU 4.61e-33 128.0 4QAZA@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_268737_3 1862825.A0A193CDY3_9VIRU 6.59e-65 208.0 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_98762_2 68219.JNXI01000031_gene5502 1.29e-22 104.0 COG0749@1|root,COG0749@2|Bacteria,2IG0A@201174|Actinobacteria 201174|Actinobacteria L DNA polymerase - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_135097_2 46681.XP_001738227.1 1.43e-37 140.0 2CSEE@1|root,2RBK2@2759|Eukaryota,3X9MH@554915|Amoebozoa 554915|Amoebozoa G RNA helicase - - - - - - - - - - - - RNA_helicase k59_110938_2 1157708.KB907450_gene5438 5.66e-49 194.0 28IJ1@1|root,2Z8K0@2|Bacteria,1R5PC@1224|Proteobacteria,2W0IK@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_37978_4 1566993.A0A0A7HER9_9CAUD 4.53e-50 184.0 4QEW8@10239|Viruses,4QTWI@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_37978_9 1042377.AFPJ01000024_gene772 6.42e-22 100.0 COG0463@1|root,COG0463@2|Bacteria,1MX1N@1224|Proteobacteria,1S06M@1236|Gammaproteobacteria,464R2@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyl transferase, family 2 - - - - - - - - - - - - Glycos_transf_2 k59_378218_2 186617.M9M8L2_9VIRU 1.16e-75 247.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_123230_1 317619.ANKN01000020_gene1085 1.02e-10 61.2 COG1403@1|root,COG1403@2|Bacteria,1G9FE@1117|Cyanobacteria 1117|Cyanobacteria V HNH nucleases - - - - - - - - - - - - HNH_3 k59_135099_1 396595.TK90_2683 5.29e-32 122.0 COG0237@1|root,COG0237@2|Bacteria,1NE9C@1224|Proteobacteria,1SCJ4@1236|Gammaproteobacteria 1236|Gammaproteobacteria H dephospho-CoA kinase activity - - - - - - - - - - - - - k59_244349_1 1618259.A0A0C5I2B5_9CIRC 1.06e-46 165.0 4QE84@10239|Viruses,4QUKR@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_159671_2 1618242.A0A0C5IBR9_9CIRC 2.37e-36 140.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_159671_3 1379708.S5SYC3_9CIRC 7.57e-48 165.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_294277_2 1158150.KB906242_gene236 3.31e-15 74.3 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,1SQ0T@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_2704_1 438753.AZC_3607 7.79e-47 171.0 COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria,2U1JR@28211|Alphaproteobacteria 28211|Alphaproteobacteria K DNA-dependent RNA polymerase - - - - - - - - - - - - RNA_pol,RPOL_N k59_136261_1 1788438.A0A190WHE1_9CIRC 9.47e-06 55.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_160733_5 1498011.A0A096XUV3_9CAUD 7.09e-65 209.0 4QAUS@10239|Viruses,4QQ2S@28883|Caudovirales 28883|Caudovirales S flavin adenine dinucleotide binding - - - - - - - - - - - - - k59_160733_7 1429794.A0A0A0Q0P0_9CAUD 4.21e-14 75.5 4QF38@10239|Viruses,4QUXM@35237|dsDNA viruses no RNA stage,4QTDX@28883|Caudovirales,4QIG3@10662|Myoviridae 10662|Myoviridae S AAA domain - GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0044237,GO:0047846 - - - - - - - - - - - k59_160733_8 1204521.I7B2R4_9CAUD 4.55e-47 162.0 4QF3X@10239|Viruses,4QWSV@35237|dsDNA viruses no RNA stage,4QT5P@28883|Caudovirales 28883|Caudovirales S oxidoreductase activity - - - - - - - - - - - - - k59_318914_2 399742.Ent638_2235 2.17e-54 188.0 COG4695@1|root,COG4695@2|Bacteria,1PFTD@1224|Proteobacteria,1RTWZ@1236|Gammaproteobacteria,3X3J3@547|Enterobacter 1236|Gammaproteobacteria S Portal protein - - - - - - - - - - - - - k59_318914_3 1231190.NA8A_23384 4.27e-141 418.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2V9W4@28211|Alphaproteobacteria,43NEB@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Phage portal protein - - - - - - - - - - - - Phage_portal k59_318914_4 194867.ALBQ01000016_gene3018 1.39e-140 419.0 COG4653@1|root,COG4653@2|Bacteria,1Q3BS@1224|Proteobacteria,2TW86@28211|Alphaproteobacteria,2K50B@204457|Sphingomonadales 204457|Sphingomonadales S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_318914_5 13690.CP98_05001 2.06e-49 166.0 COG3740@1|root,COG3740@2|Bacteria,1RKXT@1224|Proteobacteria,2U9UN@28211|Alphaproteobacteria,2K512@204457|Sphingomonadales 204457|Sphingomonadales S Caudovirus prohead serine protease - - - - - - - - - - - - Peptidase_S78 k59_318914_6 504346.B5WZR8_BPPAJ 1.83e-89 279.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_221708_2 105154.Q9MBU3_9VIRU 1.29e-18 86.7 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_366808_1 349163.Acry_0517 5.9e-34 127.0 28N1N@1|root,2ZB7Q@2|Bacteria,1R86T@1224|Proteobacteria,2U0A6@28211|Alphaproteobacteria,2JRMI@204441|Rhodospirillales 204441|Rhodospirillales H Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_1 k59_283003_2 1194526.A284_07970 5.75e-14 69.7 COG1525@1|root,COG1525@2|Bacteria,1W1ZK@1239|Firmicutes,4I0QU@91061|Bacilli,4GZMQ@90964|Staphylococcaceae 91061|Bacilli L COG1525 Micrococcal nuclease (thermonuclease) homologs - - 3.1.31.1 ko:K01174 - - - - ko00000,ko01000 - - - SNase k59_87717_2 344021.Q3YJY4_BPK1F 1.03e-26 112.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_111907_1 349161.Dred_1404 8.79e-24 104.0 2EYIP@1|root,33RSF@2|Bacteria,1VSNU@1239|Firmicutes,24YEW@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_294345_37 1150989.H6WXJ8_9CAUD 1.22e-34 137.0 4QEHG@10239|Viruses,4QVR3@35237|dsDNA viruses no RNA stage,4QSGQ@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_294345_38 1429768.W6ARW6_9CAUD 2.23e-33 124.0 4QDF4@10239|Viruses,4QY75@35237|dsDNA viruses no RNA stage,4QSXV@28883|Caudovirales,4QJB1@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_51345_1 877414.ATWA01000005_gene694 3.88e-11 68.9 COG1066@1|root,COG1066@2|Bacteria,1UHUE@1239|Firmicutes,25E2V@186801|Clostridia 186801|Clostridia O AAA domain - - - - - - - - - - - - AAA_25 k59_342808_1 1219035.NT2_13_00580 4.66e-91 282.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_197210_4 186617.M9M8L2_9VIRU 1.26e-16 87.4 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_331962_3 382638.Hac_0056 5.5e-05 45.1 COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,42KZY@68525|delta/epsilon subdivisions,2YMQF@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose gmd - 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd k59_295229_1 1385658.U5KPZ6_9VIRU 2.71e-79 256.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_355900_1 1618243.A0A0C5IAV0_9CIRC 1.58e-23 103.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_76351_1 1609634.A0A0C5AFV4_9VIRU 1.19e-47 174.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_88671_1 2003327.CAPSD_BPCHP 8.77e-47 172.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_137000_2 1520935.A0A0H3UB63_9CIRC 1.63e-21 99.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_52110_9 864051.BurJ1DRAFT_1864 9.17e-17 77.0 2FKIP@1|root,34C5S@2|Bacteria,1P5YE@1224|Proteobacteria 1224|Proteobacteria S R67 dihydrofolate reductase - - - - - - - - - - - - DHFR_2 k59_52110_11 749222.Nitsa_1194 1.09e-33 120.0 2AJ1X@1|root,319K5@2|Bacteria,1RK0X@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF2829) - - - - - - - - - - - - DUF2829 k59_258707_2 322855.Q52PS6_9CAUD 7.29e-127 394.0 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales 28883|Caudovirales S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_343785_2 103807.Q9MBZ3_9CAUD 2.65e-25 100.0 4QHC8@10239|Viruses,4QZ9A@35237|dsDNA viruses no RNA stage,4QSRC@28883|Caudovirales,4QKFD@10662|Myoviridae 10662|Myoviridae S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - - k59_137135_1 1192868.CAIU01000008_gene927 1.37e-33 130.0 COG1783@1|root,COG1783@2|Bacteria,1PE12@1224|Proteobacteria,2V9EC@28211|Alphaproteobacteria,43QJZ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Mu-like prophage FluMu protein gp28 - - - - - - - - - - - - - k59_88787_1 1131814.JAFO01000001_gene2055 2.02e-29 123.0 COG3723@1|root,COG3723@2|Bacteria,1R6DB@1224|Proteobacteria,2U82T@28211|Alphaproteobacteria 28211|Alphaproteobacteria L RecT family - - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_3910_1 145579.CAPSD_BPPHM 1.91e-75 246.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_161814_2 633131.TR2A62_1805 5.1e-24 99.8 COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,2TR8G@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose gmd - 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd k59_307610_1 1379695.S5SXZ1_9CIRC 2.28e-27 120.0 4QD5V@10239|Viruses 10239|Viruses S Viral coat protein (S domain) - GO:0003674,GO:0003676,GO:0003723,GO:0005198,GO:0005488,GO:0005509,GO:0005575,GO:0008289,GO:0019012,GO:0019028,GO:0019030,GO:0039617,GO:0039660,GO:0043167,GO:0043169,GO:0044423,GO:0046872,GO:0097159,GO:1901363 - - - - - - - - - - - k59_307610_2 1574422.A0A0A1ENW9_9CIRC 3.11e-34 132.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_307610_3 1676184.A0A186YBN5_9CIRC 2.39e-10 65.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_259457_1 186617.M9M8L2_9VIRU 1.92e-52 180.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_40645_5 1609634.A0A0C5AFT2_9VIRU 4.71e-117 348.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_259610_2 1379717.S5SY19_9CIRC 1.64e-10 62.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_259610_3 110365.A0A023B1R5 3.51e-10 65.1 2EWQP@1|root,2SYH6@2759|Eukaryota 2759|Eukaryota S RNA helicase - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_65700_1 652103.Rpdx1_2535 0.000851 49.3 2DQ9V@1|root,335IH@2|Bacteria 2|Bacteria - - - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - - k59_259613_1 742918.D4N3P2_9CIRC 1.67e-11 70.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_40878_2 1123367.C666_12660 7.04e-50 166.0 2EKAP@1|root,33E0Y@2|Bacteria,1NAAI@1224|Proteobacteria,2VZTN@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_199103_2 1536774.H70357_18230 1.68e-73 241.0 COG0464@1|root,COG0464@2|Bacteria,1TQTZ@1239|Firmicutes,4HF00@91061|Bacilli,26TXX@186822|Paenibacillaceae 91061|Bacilli O ATPase family associated with various cellular activities (AAA) - - - - - - - - - - - - AAA k59_344895_2 1123508.JH636439_gene1604 5.28e-12 71.2 29XN2@1|root,30JDF@2|Bacteria,2J498@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_4971_2 118168.MC7420_6803 2.02e-07 64.7 COG2706@1|root,COG2931@1|root,COG3391@1|root,COG2706@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria,1G0EB@1117|Cyanobacteria,1H803@1150|Oscillatoriales 1117|Cyanobacteria G PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - Calx-beta,DUF4347,He_PIG,HemolysinCabind,PPC,TIG,VCBS k59_15921_1 186617.M9M8L2_9VIRU 7.63e-51 177.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_199104_1 1547437.LL06_00810 4.59e-09 57.0 COG0338@1|root,COG0338@2|Bacteria,1PSK1@1224|Proteobacteria,2V4Q7@28211|Alphaproteobacteria,43P30@69277|Phyllobacteriaceae 28211|Alphaproteobacteria L D12 class N6 adenine-specific DNA methyltransferase - - - - - - - - - - - - MethyltransfD12 k59_199104_3 439375.Oant_0230 2.68e-11 62.4 COG0270@1|root,COG0270@2|Bacteria,1R5MR@1224|Proteobacteria,2U53Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_236365_6 1385658.U5KNR1_9VIRU 1.13e-35 132.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_248668_3 1235835.C814_01159 2.08e-15 83.2 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,3WGFC@541000|Ruminococcaceae 186801|Clostridia KL SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N,SNF2_assoc,SWIM k59_213049_3 1609634.A0A0C5AFT2_9VIRU 2.3e-84 259.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_54305_1 163908.KB235895_gene5051 1.63e-08 63.2 COG0507@1|root,COG0507@2|Bacteria,1G4VJ@1117|Cyanobacteria 1117|Cyanobacteria L DNA helicase - - 3.1.11.5 ko:K01144 - - - - ko00000,ko01000 - - - AAA_30,UvrD_C_2 k59_54305_3 1175654.A0A0S0NAG1_9CAUD 2.16e-27 105.0 4QAQV@10239|Viruses,4QUPK@35237|dsDNA viruses no RNA stage,4QPCB@28883|Caudovirales 28883|Caudovirales S protein disulfide oxidoreductase activity - - - - - - - - - - - - - k59_334013_1 582899.Hden_1190 4.42e-43 144.0 COG1694@1|root,COG1694@2|Bacteria,1N3XF@1224|Proteobacteria,2UG4F@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Mazg nucleotide pyrophosphohydrolase - - - - - - - - - - - - - k59_322051_1 1157635.KB892046_gene5783 8.55e-32 119.0 2EB9A@1|root,3359T@2|Bacteria,2INFV@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_163888_1 525246.HMPREF0058_0338 1.59e-16 79.0 COG1670@1|root,COG4696@1|root,COG1670@2|Bacteria,COG4696@2|Bacteria,2IIPK@201174|Actinobacteria,4D3RJ@85005|Actinomycetales 201174|Actinobacteria J Phosphoribosyl-ATP pyrophosphohydrolase - - - - - - - - - - - - Acetyltransf_3,PRA-PH k59_163888_5 59538.XP_005976049.1 1.54e-18 93.6 COG0209@1|root,KOG1112@2759|Eukaryota,38B81@33154|Opisthokonta,3B9IQ@33208|Metazoa,3CUAM@33213|Bilateria,48345@7711|Chordata,48Y78@7742|Vertebrata,3JEFR@40674|Mammalia,4J4KZ@91561|Cetartiodactyla 2759|Eukaryota F Ribonucleoside-diphosphate reductase large - - - - - - - - - - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN k59_91256_4 1692252.A0A0K1RL35_9CIRC 1.35e-17 88.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_224923_2 1449347.JQLN01000004_gene7029 1.84e-16 83.2 2C57A@1|root,33VMF@2|Bacteria,2ITD2@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - Peptidase_C1 k59_297638_6 469617.FUAG_00827 2.88e-69 227.0 COG0863@1|root,COG0863@2|Bacteria,37A63@32066|Fusobacteria 32066|Fusobacteria L DNA methylase - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_5984_4 1234888.K0A2J2_9VIRU 3.2e-33 134.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_54459_2 157783.LK03_06585 2.41e-12 79.7 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_152716_1 1229780.BN381_640016 7.77e-28 115.0 COG0863@1|root,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine bglIM - 2.1.1.113,2.1.1.72 ko:K00571,ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_55228_1 49964.Q94MS4_9CAUD 7.01e-40 150.0 4QCUF@10239|Viruses,4QV7U@35237|dsDNA viruses no RNA stage,4QQ89@28883|Caudovirales,4QNCY@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_6810_1 1168059.KB899087_gene1375 0.000228 47.0 COG4675@1|root,COG4675@2|Bacteria,1MZY9@1224|Proteobacteria,2UC68@28211|Alphaproteobacteria,3F1UQ@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Phage Tail Collar Domain - - - - - - - - - - - - Collar k59_140373_1 151528.Q8W711_9CAUD 2.33e-51 183.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_79634_2 357276.EL88_08355 1.86e-52 187.0 28KN5@1|root,2ZA6E@2|Bacteria,4NIXS@976|Bacteroidetes,2FPAC@200643|Bacteroidia,4AP6T@815|Bacteroidaceae 976|Bacteroidetes - - - - - - - - - - - - - - - k59_310585_3 1173026.Glo7428_1500 2.2e-08 64.7 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1G4RW@1117|Cyanobacteria 1117|Cyanobacteria KL PFAM ParB-like nuclease domain - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - N6_N4_Mtase,ParBc k59_310585_5 1160718.SU9_22210 2.12e-11 70.9 COG1573@1|root,COG1573@2|Bacteria,2GMPT@201174|Actinobacteria 201174|Actinobacteria L Uracil-DNA glycosylase dpo - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_310585_8 1121926.AXWO01000001_gene3487 2.04e-21 91.7 COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,4EYNV@85014|Glycomycetales 201174|Actinobacteria F dUTPase dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase k59_115618_1 691965.D4P7L3_9CAUD 3.91e-74 239.0 4QBH7@10239|Viruses,4QWWF@35237|dsDNA viruses no RNA stage,4QQ8R@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_261325_1 1234888.K0A2J2_9VIRU 5.87e-28 113.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_298812_1 511051.CSE_08420 4.13e-44 155.0 COG0148@1|root,COG0148@2|Bacteria 2|Bacteria G phosphopyruvate hydratase activity eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N k59_298812_2 353496.LBU_1339 2.25e-31 114.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4ISER@91061|Bacilli,3F3U1@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate pps - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N k59_201183_1 1280694.AUJQ01000003_gene1486 2.04e-12 73.9 COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia,3NH13@46205|Pseudobutyrivibrio 186801|Clostridia M Glycosyltransferase like family 2 - - - ko:K20444 - - - - ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 - Glycos_transf_2 k59_128630_1 1236514.BAKL01000015_gene1644 2.31e-14 73.2 2C6KN@1|root,33CID@2|Bacteria,4NW71@976|Bacteroidetes,2FTV3@200643|Bacteroidia,4ARYC@815|Bacteroidaceae 976|Bacteroidetes S VRR_NUC - - - - - - - - - - - - VRR_NUC k59_80455_1 105154.Q9MBU6_9VIRU 5.42e-111 341.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_141149_1 105154.Q9MBU6_9VIRU 9.99e-08 58.5 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_347824_1 1273707.L7TH85_9CAUD 6.16e-13 70.5 4QEMB@10239|Viruses,4QVSG@35237|dsDNA viruses no RNA stage,4QQ55@28883|Caudovirales,4QP45@10744|Podoviridae 10744|Podoviridae S Bacteriophage Lambda NinG protein - - - - - - - - - - - - - k59_32079_1 1235661.K0IP52_9CAUD 2.75e-59 210.0 4QAUF@10239|Viruses,4QWIQ@35237|dsDNA viruses no RNA stage,4QUFS@28883|Caudovirales,4QNVK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_383603_1 1609634.A0A0C5AFV4_9VIRU 5.84e-60 201.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_141386_2 504346.TMP_BPPAJ 4.75e-14 76.6 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - GO:0008150,GO:0044403,GO:0044409,GO:0044411,GO:0044419,GO:0051701,GO:0051704,GO:0051828,GO:0051830,GO:0085027 - - - - - - - - - - - k59_238214_2 187303.BN69_2086 2.79e-12 67.0 COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2TT5T@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB - 4.2.1.46,4.2.1.76,5.1.3.2 ko:K01710,ko:K01784,ko:K12450 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 M00361,M00362,M00632,M00793 R00291,R00293,R02984,R06513 RC00289,RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd k59_311606_5 1282876.BAOK01000001_gene2713 5.9e-07 58.9 COG0110@1|root,COG0673@1|root,COG0110@2|Bacteria,COG0673@2|Bacteria,1MZV9@1224|Proteobacteria,2TWJW@28211|Alphaproteobacteria,4BR7B@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Hexapeptide repeat of succinyl-transferase - - 2.3.1.201 ko:K13018 ko00520,map00520 - R10100 RC00004,RC00166 ko00000,ko00001,ko01000,ko01005 - - - GFO_IDH_MocA,Hexapep,Hexapep_2 k59_187262_3 879630.E1A1X2_9CAUD 7.63e-73 239.0 4QF57@10239|Viruses,4QVID@35237|dsDNA viruses no RNA stage,4QSP7@28883|Caudovirales,4QIC6@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_7733_1 1385658.U5KPZ6_9VIRU 1.05e-88 281.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_202149_3 545695.TREAZ_0592 6.56e-22 91.7 COG1196@1|root,COG1196@2|Bacteria 2|Bacteria D nuclear chromosome segregation - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - Dam,PhageMin_Tail k59_275561_2 1385658.U5KPZ6_9VIRU 4.75e-160 473.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_275561_7 1385658.U5KNR1_9VIRU 8.12e-66 216.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_117267_3 316067.Geob_0714 3.19e-25 99.4 COG0758@1|root,COG0758@2|Bacteria,1NG7X@1224|Proteobacteria,43BE4@68525|delta/epsilon subdivisions,2WXDJ@28221|Deltaproteobacteria 28221|Deltaproteobacteria LU Protein of unknown function (DUF2493) - - - - - - - - - - - - DUF2493 k59_56943_1 1123020.AUIE01000007_gene3217 9.08e-11 66.2 2A70H@1|root,30VVP@2|Bacteria,1NFHJ@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_227584_2 1321782.HMPREF1986_00332 9.81e-16 76.6 2C6KN@1|root,32Y69@2|Bacteria,1VANX@1239|Firmicutes,24MNG@186801|Clostridia 186801|Clostridia S VRR-NUC domain - - - - - - - - - - - - VRR_NUC k59_251219_3 105154.Q9MBU0_9VIRU 4.91e-45 162.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_8480_3 556269.ACDQ01000002_gene1166 2.19e-23 95.9 2CC49@1|root,2ZBQQ@2|Bacteria,1RA92@1224|Proteobacteria,2VYII@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF1367) - - - - - - - - - - - - DUF1367 k59_349011_1 1238182.C882_1989 1.78e-24 110.0 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,2TVGJ@28211|Alphaproteobacteria,2JPR0@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_44908_3 1206741.BAFX01000172_gene7413 2.69e-22 94.4 2CICW@1|root,346YY@2|Bacteria,2HIJU@201174|Actinobacteria,4G48K@85025|Nocardiaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_187938_1 1795988.A0A140CTK3_9VIRU 3.21e-33 130.0 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_105587_2 1457393.AZ09_10465 5.33e-35 128.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2TU8N@28211|Alphaproteobacteria,2JXEZ@204441|Rhodospirillales 204441|Rhodospirillales L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_337035_1 172088.AUGA01000017_gene2388 3.41e-33 130.0 COG0305@1|root,COG0305@2|Bacteria,1QT50@1224|Proteobacteria,2TTND@28211|Alphaproteobacteria,3JW9V@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L TOPRIM - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - AAA_25,DnaB_C,Toprim_2,Toprim_4 k59_179227_1 1165094.RINTHH_3920 4.86e-32 122.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_154787_1 691965.D4P7I3_9CAUD 1.06e-54 193.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_275789_1 1437882.AZRU01000032_gene21 5.19e-11 64.7 28HEE@1|root,2Z7QU@2|Bacteria,1MXU6@1224|Proteobacteria,1RZSJ@1236|Gammaproteobacteria,1YF4W@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_81614_1 654929.REP_PCV1C 3.4e-40 150.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_179228_2 375286.mma_2719 1.67e-33 139.0 COG5283@1|root,COG5283@2|Bacteria,1R5FU@1224|Proteobacteria,2VPNW@28216|Betaproteobacteria,47876@75682|Oxalobacteraceae 28216|Betaproteobacteria NU Phage-related minor tail protein - - - - - - - - - - - - - k59_33263_3 1123487.KB892865_gene1401 9.26e-29 110.0 2CIC0@1|root,2ZUFF@2|Bacteria,1PB71@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_301713_2 1366050.N234_18785 1.16e-19 87.4 2D0K9@1|root,32T8S@2|Bacteria,1MZRW@1224|Proteobacteria,2VW7X@28216|Betaproteobacteria,1KE19@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_106634_1 1121957.ATVL01000009_gene1240 1.08e-05 53.1 COG3541@1|root,COG3541@2|Bacteria,4NFW8@976|Bacteroidetes,47KUZ@768503|Cytophagia 976|Bacteroidetes S Predicted nucleotidyltransferase - - - - - - - - - - - - Nuc-transf k59_46019_1 324602.Caur_0075 4.29e-35 133.0 COG0338@1|root,COG0338@2|Bacteria,2G7SZ@200795|Chloroflexi 200795|Chloroflexi L PFAM D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_203997_1 1089439.KB902270_gene2574 1.24e-08 61.2 COG4379@1|root,COG4379@2|Bacteria,1MX68@1224|Proteobacteria 1224|Proteobacteria S Tail protein gpP - - - - - - - - - - - Phage_GPD k59_58148_2 102125.Xen7305DRAFT_00036340 3.86e-16 80.9 2DKXV@1|root,30THP@2|Bacteria,1GQMH@1117|Cyanobacteria 1117|Cyanobacteria S Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_2 k59_313409_2 402626.Rpic_2295 6.2e-09 61.6 28MJ5@1|root,2ZAVR@2|Bacteria,1R5CR@1224|Proteobacteria,2W1FE@28216|Betaproteobacteria,1KCA3@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_217141_1 1123399.AQVE01000018_gene3340 1.05e-12 70.5 COG3926@1|root,COG3926@2|Bacteria,1MVXW@1224|Proteobacteria,1RRB6@1236|Gammaproteobacteria,462PJ@72273|Thiotrichales 72273|Thiotrichales S Predicted Peptidoglycan domain - - - - - - - - - - - - Glyco_hydro_108,PG_binding_3 k59_155772_1 1218352.B597_019670 4.22e-25 104.0 COG0863@1|root,COG0863@2|Bacteria,1MY4G@1224|Proteobacteria,1RQHA@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.113,2.1.1.72 ko:K00571,ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_338065_1 1385658.U5KPZ6_9VIRU 1.13e-65 221.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_385563_4 537013.CLOSTMETH_01710 3.62e-10 63.2 2EF3G@1|root,338WJ@2|Bacteria,1VHUW@1239|Firmicutes,24R77@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_302156_2 105154.Q9MBU6_9VIRU 1.87e-46 165.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_82837_2 1155714.KB891988_gene1269 1.03e-14 80.5 COG0791@1|root,COG3409@1|root,COG0791@2|Bacteria,COG3409@2|Bacteria,2I61A@201174|Actinobacteria 201174|Actinobacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - NLPC_P60,PG_binding_1 k59_21034_2 105154.Q9MBU3_9VIRU 8.28e-17 82.8 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_21034_3 105154.Q9MBU6_9VIRU 1.88e-125 377.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_291135_2 82654.Pse7367_3949 5.02e-10 63.5 COG0507@1|root,COG5362@1|root,COG0507@2|Bacteria,COG5362@2|Bacteria 2|Bacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD pacB - - - - - - - - - - - Terminase_6,Terminase_6C k59_96337_2 502347.ESCAB7627_2180 9.71e-48 155.0 COG3179@1|root,COG3179@2|Bacteria,1RE8K@1224|Proteobacteria,1S4U8@1236|Gammaproteobacteria 1236|Gammaproteobacteria S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Peptidase_M15_4 k59_204612_2 1499685.CCFJ01000053_gene3043 4.09e-08 55.8 2E2AR@1|root,2ZE28@2|Bacteria,1V2CG@1239|Firmicutes,4HQUA@91061|Bacilli 91061|Bacilli S HNH endonuclease - - - - - - - - - - - - HNH_3 k59_291138_2 1166948.JPZL01000002_gene1629 8.73e-13 67.8 2DRN8@1|root,33CCM@2|Bacteria,1NGRN@1224|Proteobacteria 1224|Proteobacteria - - - - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - - k59_132218_1 1234888.K0A2J2_9VIRU 6.29e-69 228.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_58888_1 557598.LHK_01771 7.16e-05 44.3 2DHT3@1|root,300U6@2|Bacteria,1NHUH@1224|Proteobacteria 1224|Proteobacteria S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 k59_119136_1 1122179.KB890417_gene3273 1.04e-33 131.0 COG2425@1|root,COG2425@2|Bacteria 2|Bacteria S positive regulation of ATPase activity rsr - - ko:K11089 ko05322,map05322 - - - ko00000,ko00001 - - - TROVE,VWA_CoxE k59_386321_2 340435.A0A7I6_9CAUD 3.52e-34 130.0 4QCF5@10239|Viruses,4QV2A@35237|dsDNA viruses no RNA stage,4QPJI@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_265334_1 204773.HEAR2295 9.01e-102 300.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2W3M1@28216|Betaproteobacteria,475QA@75682|Oxalobacteraceae 28216|Betaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_181423_2 1618259.A0A0C5I2B5_9CIRC 2.03e-70 226.0 4QE84@10239|Viruses,4QUKR@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_83941_1 1609634.A0A0C5AFV4_9VIRU 1.43e-55 189.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_96944_1 1055815.AYYA01000003_gene1949 3.05e-78 240.0 COG5527@1|root,COG5527@2|Bacteria,1RD9C@1224|Proteobacteria,1T07W@1236|Gammaproteobacteria,3NTFJ@468|Moraxellaceae 1224|Proteobacteria L Initiator Replication protein - - - - - - - - - - - - Rep_3 k59_218485_1 1788443.A0A190WHA2_9CIRC 3.71e-08 59.3 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_241320_1 691965.D4P7D6_9CAUD 1.02e-53 189.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_35500_1 1341151.ASZU01000008_gene1531 4.77e-10 66.6 COG1783@1|root,COG1783@2|Bacteria,1VK0H@1239|Firmicutes,4HQ2H@91061|Bacilli 91061|Bacilli S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_10400_2 211114.JOEF01000005_gene2053 8.17e-15 77.0 COG0714@1|root,COG0714@2|Bacteria,2IDEW@201174|Actinobacteria,4EAR1@85010|Pseudonocardiales 201174|Actinobacteria O AAA domain (dynein-related subfamily) - - 6.6.1.2 ko:K09882 ko00860,ko01100,map00860,map01100 - R05227 RC02000 ko00000,ko00001,ko01000 - - - AAA_5 k59_84225_1 1118235.CAJH01000041_gene2650 2.4e-72 254.0 COG0740@1|root,COG0740@2|Bacteria,1MUQ9@1224|Proteobacteria,1RRQA@1236|Gammaproteobacteria,1X3TK@135614|Xanthomonadales 135614|Xanthomonadales OU Belongs to the peptidase S14 family - - - - - - - - - - - - CLP_protease,Mu-like_gpT k59_71990_1 589873.EP13_13740 2.44e-28 112.0 COG0457@1|root,COG0457@2|Bacteria,1Q0TK@1224|Proteobacteria,1SFRP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_2 k59_108531_1 691965.D4P7L7_9CAUD 1.79e-85 279.0 4QB9J@10239|Viruses,4QXFE@35237|dsDNA viruses no RNA stage,4QS1Z@28883|Caudovirales,4QN8F@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_241950_1 420324.KI912039_gene1986 1.36e-22 98.2 COG2263@1|root,COG2263@2|Bacteria,1R9Y2@1224|Proteobacteria,2U6HR@28211|Alphaproteobacteria 28211|Alphaproteobacteria J DNA repair - - - - - - - - - - - - MTS k59_303644_2 1280682.AUKA01000008_gene3173 0.000281 48.5 COG3864@1|root,COG3864@2|Bacteria,1TQ6J@1239|Firmicutes,24C34@186801|Clostridia,4BY92@830|Butyrivibrio 186801|Clostridia S Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N k59_387377_2 462590.A9J512_BPPYU 2.06e-25 103.0 4QG7K@10239|Viruses,4QZQI@35237|dsDNA viruses no RNA stage,4QQZP@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_47857_3 1618254.A0A0C5IBG4_9CIRC 1.53e-142 406.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_72629_1 756272.Plabr_0196 1.11e-14 73.6 28HHC@1|root,2Z7T2@2|Bacteria,2J15Z@203682|Planctomycetes 203682|Planctomycetes S AAA domain - - - - - - - - - - - - AAA_24 k59_266083_1 926550.CLDAP_25590 1.82e-48 174.0 COG1572@1|root,COG1572@2|Bacteria 2|Bacteria NU bacterial-type flagellum-dependent cell motility - - - - - - - - - - - - BatA,CARDB,DUF3367,DUF4091,DUF4159 k59_278712_5 105154.Q9MBU0_9VIRU 4e-51 179.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_145743_1 1121430.JMLG01000007_gene2516 1e-19 95.9 COG3598@1|root,COG3598@2|Bacteria,1UJSF@1239|Firmicutes,25F8S@186801|Clostridia,263X1@186807|Peptococcaceae 186801|Clostridia L Bifunctional DNA primase/polymerase, N-terminal - - - - - - - - - - - - PriCT_1,Prim-Pol k59_266292_1 156889.Mmc1_1720 1.21e-28 117.0 28QU5@1|root,2ZD9H@2|Bacteria,1RAU8@1224|Proteobacteria,2UAGW@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_387784_1 1234888.K0A2J2_9VIRU 3.74e-37 141.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_11403_1 1121438.JNJA01000011_gene1810 8.76e-45 167.0 COG0037@1|root,COG0154@1|root,COG0037@2|Bacteria,COG0154@2|Bacteria,1MVXT@1224|Proteobacteria,43BTS@68525|delta/epsilon subdivisions,2X74P@28221|Deltaproteobacteria 28221|Deltaproteobacteria D tRNA processing - - - - - - - - - - - - - k59_48241_1 335284.Pcryo_2482 1.76e-134 384.0 COG2197@1|root,COG2197@2|Bacteria,1N33D@1224|Proteobacteria,1RZCA@1236|Gammaproteobacteria,3NNFM@468|Moraxellaceae 1236|Gammaproteobacteria KT Primase C terminal 1 (PriCT-1) - - - - - - - - - - - - HTH_23,PriCT_1,Replicase k59_169429_1 765869.BDW_04410 0.000171 54.3 COG3210@1|root,COG3210@2|Bacteria,1NED3@1224|Proteobacteria,42WDX@68525|delta/epsilon subdivisions,2MTVC@213481|Bdellovibrionales,2WRDH@28221|Deltaproteobacteria 213481|Bdellovibrionales U cell wall surface anchor family protein - - - - - - - - - - - - Peptidase_S74 k59_254785_3 903814.ELI_1810 8.55e-20 92.4 COG1216@1|root,COG1216@2|Bacteria,1VEIR@1239|Firmicutes,24SFJ@186801|Clostridia,25YYM@186806|Eubacteriaceae 186801|Clostridia S Protein of unknown function (DUF616) - - - - - - - - - - - - DUF616 k59_254785_4 1047013.AQSP01000144_gene834 2.21e-17 89.0 COG0451@1|root,COG0451@2|Bacteria,2NQVT@2323|unclassified Bacteria 2|Bacteria M Polysaccharide biosynthesis protein - - - ko:K13318,ko:K13322,ko:K16439,ko:K19857 ko00523,ko01055,ko01130,map00523,map01055,map01130 M00798,M00799,M00800 R06436,R06629,R11042,R11047 RC00182,RC00261 ko00000,ko00001,ko00002,ko01000 - - - Epimerase k59_254785_6 756272.Plabr_3057 3.29e-07 60.5 COG1216@1|root,COG1216@2|Bacteria,2IZF5@203682|Planctomycetes 203682|Planctomycetes S Glycosyltransferase like family 2 - - - - - - - - - - - - Glyco_transf_7C,Glycos_transf_2 k59_254785_7 1317118.ATO8_19264 7.19e-16 88.2 COG1215@1|root,COG4641@1|root,COG1215@2|Bacteria,COG4641@2|Bacteria,1RIJ7@1224|Proteobacteria,2U1KG@28211|Alphaproteobacteria,4KNKV@93682|Roseivivax 28211|Alphaproteobacteria M Glycosyltransferase like family 2 exoU - - - - - - - - - - - Glycos_transf_2 k59_254785_9 29908.U7Q190 4.94e-05 56.2 2EEPU@1|root,2SK24@2759|Eukaryota,39XQC@33154|Opisthokonta,3NXM7@4751|Fungi,3QM42@4890|Ascomycota,2117A@147550|Sordariomycetes,3UV1P@5151|Ophiostomatales 4751|Fungi O Pectate lyase superfamily protein - - - - - - - - - - - - LysM,Pectate_lyase_3,WSC k59_315786_4 1123508.JH636448_gene7701 0.000146 45.8 COG4422@1|root,COG4422@2|Bacteria 2|Bacteria F Protein of unknown function (DUF5131) - - - - - - - - - - - - DUF5131 k59_315786_5 1033738.CAEP01000047_gene537 4.32e-13 69.3 COG4570@1|root,COG4570@2|Bacteria,1VF2H@1239|Firmicutes,4HJ0V@91061|Bacilli,26HTM@186818|Planococcaceae 91061|Bacilli L Endodeoxyribonuclease RusA rusA - - - - - - - - - - - RusA k59_278938_1 323097.Nham_0587 1.47e-29 126.0 COG1520@1|root,COG1520@2|Bacteria 2|Bacteria S amino acid activation for nonribosomal peptide biosynthetic process - - - - - - - - - - - - FG-GAP_2,PQQ_2 k59_254788_1 1618247.A0A0C5IMK7_9CIRC 0.000475 47.4 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_363676_1 948071.S4S2S9_9CAUD 2.85e-40 148.0 4QBYN@10239|Viruses,4QZT8@35237|dsDNA viruses no RNA stage,4QR5G@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_266484_1 49964.Q94MS5_9CAUD 6.07e-31 132.0 4QG38@10239|Viruses,4QY33@35237|dsDNA viruses no RNA stage,4QQVI@28883|Caudovirales,4QNWM@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_266487_1 644107.SL1157_2511 1.42e-06 56.6 COG3391@1|root,COG3391@2|Bacteria,1MXN7@1224|Proteobacteria,2TR83@28211|Alphaproteobacteria,4NAE9@97050|Ruegeria 28211|Alphaproteobacteria S GTA TIM-barrel-like domain - - - - - - - - - - - - GTA_TIM,Phage-tail_3 k59_170019_1 1211777.BN77_4169 7.04e-24 98.6 2C5GI@1|root,2Z8C1@2|Bacteria,1R8XM@1224|Proteobacteria,2TUME@28211|Alphaproteobacteria,4BJKS@82115|Rhizobiaceae 28211|Alphaproteobacteria S P22 coat protein - gene protein 5 - - - - - - - - - - - - P22_CoatProtein k59_170019_3 367299.JOEE01000003_gene2807 0.000131 48.9 COG0500@1|root,COG2226@2|Bacteria,2HX63@201174|Actinobacteria,4FF0P@85021|Intrasporangiaceae 201174|Actinobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 k59_170019_4 1097668.BYI23_A015210 3e-25 106.0 COG1216@1|root,COG1216@2|Bacteria,1R554@1224|Proteobacteria,2VKBV@28216|Betaproteobacteria,1K6ER@119060|Burkholderiaceae 28216|Betaproteobacteria S Glycosyl transferase, family 2 - - - - - - - - - - - - - k59_170019_6 1219049.SP5_068_01130 3.98e-12 69.3 2CC8M@1|root,308VJ@2|Bacteria,1R789@1224|Proteobacteria,2U2NB@28211|Alphaproteobacteria,2K46P@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - k59_170024_1 1692242.A0A0K1RL37_9CIRC 3.75e-57 188.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_23169_1 1385658.U5KNR1_9VIRU 2.47e-46 161.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_388282_1 1788445.A0A190WHA3_9CIRC 2.37e-23 101.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388282_2 1692252.A0A0K1RL35_9CIRC 2.15e-18 85.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_242960_1 44056.XP_009033424.1 5.88e-46 172.0 COG5108@1|root,KOG1038@2759|Eukaryota 2759|Eukaryota K DNA-directed 5'-3' RNA polymerase activity RpoT GO:0000428,GO:0000959,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006351,GO:0006390,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034245,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0098798,GO:0140053,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K00960,ko:K10908,ko:K11446 - - - - ko00000,ko01000,ko01009,ko03029,ko03036 - - - RNA_pol,RPOL_N k59_12043_1 691965.D4P7I3_9CAUD 0.0 926.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_388334_4 1211115.ALIQ01000188_gene670 0.000232 46.2 COG1876@1|root,COG1876@2|Bacteria,1NIJK@1224|Proteobacteria 1224|Proteobacteria M D-alanyl-D-alanine carboxypeptidase - - 3.4.17.14 ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - TMP_2,VanY k59_267022_1 158500.BV97_01989 5.78e-17 86.3 COG0553@1|root,COG2263@1|root,COG0553@2|Bacteria,COG2263@2|Bacteria,1MXQH@1224|Proteobacteria,2TR5V@28211|Alphaproteobacteria,2K08X@204457|Sphingomonadales 204457|Sphingomonadales KL methylase - - - - - - - - - - - - AAA_34,Helicase_C_4 k59_191191_1 1288298.rosmuc_03156 1.55e-12 68.2 COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2TRU2@28211|Alphaproteobacteria,46P8R@74030|Roseovarius 28211|Alphaproteobacteria L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k59_267023_2 102125.Xen7305DRAFT_00046030 1.13e-30 127.0 COG0457@1|root,COG0457@2|Bacteria,1G3MN@1117|Cyanobacteria 1117|Cyanobacteria K PFAM sulfotransferase - - - - - - - - - - - - Sulfotransfer_1,TPR_1,TPR_11,TPR_2,TPR_8 k59_364189_1 1609634.A0A0C5AFV4_9VIRU 5.75e-104 319.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_364189_3 1609634.A0A0C5AFT2_9VIRU 5.06e-139 404.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_364189_6 1458275.AZ34_10360 1.85e-41 145.0 2EKAP@1|root,33E0Y@2|Bacteria,1NAAI@1224|Proteobacteria,2VZTN@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_364189_8 1609634.A0A0C5ANA6_9VIRU 8.39e-27 109.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_388336_4 645099.MREP_BBTVA 8.42e-09 60.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_191242_1 1218084.BBJK01000130_gene7124 9.78e-23 102.0 COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,2VJNV@28216|Betaproteobacteria,1K2NV@119060|Burkholderiaceae 28216|Betaproteobacteria M Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8 k59_267080_2 948071.S4S2F8_9CAUD 1.18e-08 59.3 4QGCH@10239|Viruses,4QYIQ@35237|dsDNA viruses no RNA stage,4QU4V@28883|Caudovirales,4QNJ3@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_23783_2 350688.Clos_1130 3.42e-08 53.5 COG3108@1|root,COG3108@2|Bacteria,1VFRJ@1239|Firmicutes,24R9N@186801|Clostridia,36TIF@31979|Clostridiaceae 186801|Clostridia S Peptidase M15A - - 3.4.17.14 ko:K08640 - - - - ko00000,ko01000,ko01002,ko01011 - - - PG_binding_1,Peptidase_M15_3 k59_388495_1 1618247.A0A0C5IMK7_9CIRC 6.61e-10 65.1 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_388498_1 1618248.A0A0C5IB82_9CIRC 3.12e-83 259.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388499_2 1618248.A0A0C5IB82_9CIRC 8.04e-13 68.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_243102_1 679935.Alfi_0795 3.91e-43 145.0 2E6PI@1|root,3319W@2|Bacteria,4NSA1@976|Bacteroidetes,2FT5Y@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_170191_4 349163.Acry_0517 3.03e-13 71.6 28N1N@1|root,2ZB7Q@2|Bacteria,1R86T@1224|Proteobacteria,2U0A6@28211|Alphaproteobacteria,2JRMI@204441|Rhodospirillales 204441|Rhodospirillales H Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_1 k59_194492_1 426114.THI_1427 8.53e-09 57.0 COG1846@1|root,COG1846@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity - - - - - - - - - - - - MarR,MarR_2 k59_24351_3 1238190.AMQY01000021_gene1593 7.64e-52 196.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,1S0Q1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L ORF located using Glimmer RBSfinder - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_133716_1 865938.Weevi_0272 1.7e-41 149.0 2DNQJ@1|root,32YKF@2|Bacteria,4PIY6@976|Bacteroidetes,1IAFC@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_145910_2 272563.CD630_31510 1.74e-05 48.5 COG3935@1|root,COG3935@2|Bacteria,1VGQ6@1239|Firmicutes,24J03@186801|Clostridia,25UB2@186804|Peptostreptococcaceae 186801|Clostridia L DnaD domain protein - - - - - - - - - - - - - k59_303847_3 1305708.M9Q2I2_9CAUD 1.9e-13 71.6 4QBDJ@10239|Viruses,4QRE4@28883|Caudovirales,4QN54@10699|Siphoviridae 10699|Siphoviridae S Phage protein (N4 Gp49/phage Sf6 gene 66) family - - - - - - - - - - - - - k59_72963_2 1692255.A0A0K1RL52_9CIRC 8.27e-95 290.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_73106_3 1609634.A0A0C5AFV4_9VIRU 1.05e-229 650.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_73106_4 1609634.A0A0C5ANA6_9VIRU 1.07e-26 109.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_73106_7 1609634.A0A0C5AFT2_9VIRU 3.58e-72 229.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_328268_1 1379695.S5TNA9_9CIRC 1.22e-38 145.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_194627_1 1121381.JNIV01000036_gene3370 1.84e-42 160.0 COG0675@1|root,COG0675@2|Bacteria,1WJ2V@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L Probable transposase - - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon k59_206779_1 1147139.A0A0A6Z5D3_9CAUD 1.12e-23 99.8 4QEQS@10239|Viruses,4QVDS@35237|dsDNA viruses no RNA stage,4QSJE@28883|Caudovirales,4QP20@10744|Podoviridae 10744|Podoviridae S methyltransferase activity - - - - - - - - - - - - - k59_182407_1 105154.Q9MBU6_9VIRU 6.38e-107 328.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_182407_4 1609634.A0A0C5AFT2_9VIRU 5.03e-44 161.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_182407_6 145579.CAPSD_BPPHM 4.15e-72 236.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_146017_2 928210.CALU01000006_gene631 1.45e-09 63.5 COG3756@1|root,COG3756@2|Bacteria,1NQA5@1224|Proteobacteria,2UXA9@28211|Alphaproteobacteria,48UQM@772|Bartonellaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1376) - - - - - - - - - - - - DUF1376 k59_352603_1 1081644.IMCC13023_03410 2.93e-57 189.0 COG0451@1|root,COG0451@2|Bacteria,2GK8K@201174|Actinobacteria,4FMTN@85023|Microbacteriaceae 201174|Actinobacteria M Male sterility protein - - 5.1.3.2,5.1.3.25 ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 M00361,M00362,M00632 R00291,R02984,R10279 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd k59_279744_2 490913.B0FLN5_9CAUD 8.45e-21 97.8 4QGGR@10239|Viruses,4QZHR@35237|dsDNA viruses no RNA stage,4QUGZ@28883|Caudovirales,4QNY3@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_279744_3 1921008.Q6XQF0_BPT1 3.31e-08 58.2 4QAIU@10239|Viruses,4QPDE@28883|Caudovirales,4QKM7@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k59_279744_5 1173762.S4TT67_9CAUD 6.49e-57 195.0 4QCT5@10239|Viruses,4QYJH@35237|dsDNA viruses no RNA stage,4QTPG@28883|Caudovirales,4QNK2@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_255240_2 1161935.H9D1E7_9CAUD 3.03e-60 207.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_133854_2 382464.ABSI01000012_gene1961 3.67e-09 61.6 28N1N@1|root,2ZB7Q@2|Bacteria 2|Bacteria H PFAM sulfotransferase - - - - - - - - - - - - Sulfotransfer_1 k59_97362_1 1458697.W6E8I7_9CAUD 3.51e-22 94.0 4QE4J@10239|Viruses,4QUX0@35237|dsDNA viruses no RNA stage,4QTDJ@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_24518_10 691965.D4P7H8_9CAUD 9.27e-36 132.0 4QG1E@10239|Viruses,4QZE1@35237|dsDNA viruses no RNA stage,4QU6Q@28883|Caudovirales,4QMKH@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_24518_13 665956.HMPREF1032_00640 4.03e-49 172.0 2A0KC@1|root,2ZGJK@2|Bacteria,1V2JS@1239|Firmicutes,24H6R@186801|Clostridia,3WNJK@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_304556_2 1906.SFRA_31460 1.2e-12 65.5 2BEJV@1|root,328B9@2|Bacteria,2IRZR@201174|Actinobacteria 201174|Actinobacteria K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA - - - ko:K18955 - - - - ko00000,ko03000 - - - Whib k59_207458_1 665950.HMPREF1025_02006 9.88e-40 136.0 2ARVA@1|root,31H70@2|Bacteria,1V7JT@1239|Firmicutes,24JPE@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - HK97-gp10_like k59_207458_2 428125.CLOLEP_01422 6.68e-149 503.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,3WN92@541000|Ruminococcaceae 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_134314_3 1463921.JODF01000137_gene5764 0.00022 45.8 2BTRZ@1|root,32NZ8@2|Bacteria,2GXPN@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_25010_1 1279038.KB907337_gene131 4.29e-22 92.0 2E645@1|root,330T3@2|Bacteria,1NEGX@1224|Proteobacteria,2UJTA@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_122331_1 411460.RUMTOR_01342 5.63e-26 106.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_170768_1 1609634.A0A0C5AFV4_9VIRU 2.79e-136 405.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_170768_2 1609634.A0A0C5ANA6_9VIRU 8.31e-17 83.6 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_170768_4 1385658.U5KNR1_9VIRU 3.61e-22 97.8 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_170768_6 186617.M9M8L2_9VIRU 5.23e-56 188.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_377560_3 1300150.EMQU_0719 1.66e-06 59.7 COG3979@1|root,COG3979@2|Bacteria,1UJCX@1239|Firmicutes,4IT5P@91061|Bacilli,4B23H@81852|Enterococcaceae 91061|Bacilli S Peptidase M60-like family - - - - - - - - - - - - CBM_5_12,M60-like_N,Mucin_bdg,Peptidase_M60,fn3 k59_49422_7 1346791.M529_02355 5.66e-37 140.0 COG0175@1|root,COG0175@2|Bacteria,1QZJ1@1224|Proteobacteria,2U233@28211|Alphaproteobacteria 28211|Alphaproteobacteria EH sulfate reduction - - - - - - - - - - - - - k59_219797_1 563192.HMPREF0179_03434 3.1e-90 291.0 28IA2@1|root,2Z8CQ@2|Bacteria,1PQM2@1224|Proteobacteria,42Y9U@68525|delta/epsilon subdivisions,2WTUC@28221|Deltaproteobacteria,2MARZ@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_122424_1 762982.HMPREF9442_01222 1.96e-41 147.0 COG0863@1|root,COG0863@2|Bacteria,4NQQ1@976|Bacteroidetes 976|Bacteroidetes L DNA methylase - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_196214_2 665956.HMPREF1032_00640 8.14e-31 120.0 2A0KC@1|root,2ZGJK@2|Bacteria,1V2JS@1239|Firmicutes,24H6R@186801|Clostridia,3WNJK@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_269052_1 272558.10176158 2.12e-09 59.7 COG2963@1|root,COG2963@2|Bacteria,1V6XW@1239|Firmicutes,4HIUS@91061|Bacilli,1ZNRZ@1386|Bacillus 91061|Bacilli L Homeodomain-like domain - - - - - - - - - - - - HTH_23 k59_269052_2 1437882.AZRU01000132_gene6658 3.06e-42 155.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,1S0WX@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6C k59_50453_1 1476390.A0A060RIN6_9CAUD 3.53e-13 74.3 4QB5N@10239|Viruses,4R0DQ@35237|dsDNA viruses no RNA stage,4QUH8@28883|Caudovirales,4QMVX@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_50453_2 1192868.CAIU01000008_gene924 1.49e-141 409.0 COG5492@1|root,COG5492@2|Bacteria,1R69J@1224|Proteobacteria,2UA50@28211|Alphaproteobacteria 28211|Alphaproteobacteria N domain, Protein - - - - - - - - - - - - - k59_1800_1 694430.Natoc_2278 1.42e-10 72.0 COG3378@1|root,arCOG06914@2157|Archaea,2XYEY@28890|Euryarchaeota,23WKP@183963|Halobacteria 183963|Halobacteria S Phage plasmid primase, P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N k59_98980_4 1234888.K0A2R8_9VIRU 1.09e-24 108.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_98980_6 1234888.K0A2J2_9VIRU 1.64e-117 361.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_282065_1 47839.CCAU010000019_gene3131 8.68e-29 125.0 COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria,234JE@1762|Mycobacteriaceae 201174|Actinobacteria L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3 k59_13483_1 1096930.L284_17150 5.17e-06 52.4 2ATMD@1|root,31J5V@2|Bacteria,1RH31@1224|Proteobacteria,2UBNT@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tail tubular protein - - - - - - - - - - - - Tube k59_183541_1 1197951.I6RT34_9CAUD 5.1e-57 193.0 4QGAG@10239|Viruses,4R0KB@35237|dsDNA viruses no RNA stage,4QUA4@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_38271_3 748280.NH8B_2804 1.42e-12 75.5 COG5377@1|root,COG5377@2|Bacteria,1MWP8@1224|Proteobacteria,2VJH5@28216|Betaproteobacteria,2KSEE@206351|Neisseriales 206351|Neisseriales L YqaJ-like viral recombinase domain - - - - - - - - - - - - YqaJ k59_244682_1 1788454.A0A190WHE4_9CIRC 1.13e-18 91.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_210111_12 1124982.MSI_23280 2.1e-34 127.0 COG4712@1|root,COG4712@2|Bacteria 2|Bacteria S DNA recombination - - - - - - - - - - - - Rad52_Rad22 k59_319348_1 1618257.A0A0C5IBI9_9CIRC 4.99e-27 110.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_367250_1 1266908.AQPB01000051_gene2466 1.88e-115 360.0 COG4653@1|root,COG4653@2|Bacteria,1MWMB@1224|Proteobacteria,1S4MJ@1236|Gammaproteobacteria,1X0RU@135613|Chromatiales 135613|Chromatiales S Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_112411_1 105154.Q9MBU3_9VIRU 3.65e-09 60.5 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_270262_6 105154.Q9MBU6_9VIRU 1.26e-100 316.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_245932_1 31870.EFQ27413 0.000751 48.5 COG1004@1|root,KOG2666@2759|Eukaryota,38BE6@33154|Opisthokonta,3NWU3@4751|Fungi,3QN2B@4890|Ascomycota,215AU@147550|Sordariomycetes,1ETY0@1028384|Glomerellales 4751|Fungi GT Nucleotide sugar dehydrogenase - - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N k59_75959_1 1385658.U5KPZ6_9VIRU 1.14e-163 478.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_75959_5 1609634.A0A0C5AFT2_9VIRU 2.9e-69 225.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_75959_7 105154.Q9MBU6_9VIRU 2.32e-45 161.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_319355_1 1229760.K4I378_9CAUD 5.33e-15 71.2 4QG00@10239|Viruses,4QZDS@35237|dsDNA viruses no RNA stage,4QTM4@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_331565_3 318586.Pden_3182 1.46e-37 146.0 COG0270@1|root,COG0270@2|Bacteria,1R5MR@1224|Proteobacteria,2U53Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_197733_1 1173762.S4TNW6_9CAUD 1.16e-23 101.0 4QEFX@10239|Viruses,4QYYG@35237|dsDNA viruses no RNA stage,4QRRV@28883|Caudovirales,4QNTK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_197733_2 1173762.S4TRT2_9CAUD 9.85e-39 141.0 4QF0B@10239|Viruses,4QX8P@35237|dsDNA viruses no RNA stage,4QSJT@28883|Caudovirales,4QNNK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_270404_3 395492.Rleg2_2432 1.9e-125 381.0 COG5362@1|root,COG5362@2|Bacteria,1NKZK@1224|Proteobacteria,2U4BJ@28211|Alphaproteobacteria,4BMKJ@82115|Rhizobiaceae 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_40598_1 1125863.JAFN01000001_gene1269 1.01e-07 52.8 2C2IA@1|root,2ZW5P@2|Bacteria,1PB15@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_28970_1 1038867.AXAY01000025_gene2082 2.86e-46 167.0 COG0417@1|root,COG0417@2|Bacteria,1R7PE@1224|Proteobacteria,2TRUR@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA replication proofreading - - - - - - - - - - - - - k59_28970_3 1457393.AZ09_10465 3.25e-29 112.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2TU8N@28211|Alphaproteobacteria,2JXEZ@204441|Rhodospirillales 204441|Rhodospirillales L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_259414_3 1609634.A0A0C5AFT2_9VIRU 1.79e-40 145.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_259414_6 1609634.A0A0C5AFV4_9VIRU 1.88e-218 621.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_259414_7 1609634.A0A0C5ANA6_9VIRU 1.51e-21 95.9 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_185224_1 36809.MAB_1796 1.79e-14 79.0 COG0741@1|root,COG3064@1|root,COG5283@1|root,COG5412@1|root,COG0741@2|Bacteria,COG3064@2|Bacteria,COG5283@2|Bacteria,COG5412@2|Bacteria,2I92I@201174|Actinobacteria,239EM@1762|Mycobacteriaceae 201174|Actinobacteria M Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_89692_2 1234888.K0A2J2_9VIRU 2.27e-93 297.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_356802_2 32057.KB217481_gene8623 0.000148 44.3 COG1357@1|root,COG1357@2|Bacteria,1G37B@1117|Cyanobacteria,1HRT0@1161|Nostocales 1117|Cyanobacteria S Pentapeptide repeats (9 copies) - - - - - - - - - - - - Pentapeptide k59_174961_2 1088869.GMO_00980 1.18e-07 57.4 COG5352@1|root,COG5352@2|Bacteria,1RHI6@1224|Proteobacteria,2TS7F@28211|Alphaproteobacteria,2JT05@204441|Rhodospirillales 204441|Rhodospirillales S GcrA cell cycle regulator - - - ko:K13583 ko04112,map04112 - - - ko00000,ko00001 - - - GcrA k59_89864_3 1400525.JNIU01000001_gene590 1.46e-09 59.7 298AD@1|root,2ZVFX@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_40763_1 232348.ADXL01000014_gene732 4.07e-17 80.9 COG5055@1|root,COG5055@2|Bacteria,1GPCA@1117|Cyanobacteria,1H2VP@1129|Synechococcus 1117|Cyanobacteria L COG5055 Recombination DNA repair protein (RAD52 pathway) - - - - - - - - - - - - Rad52_Rad22 k59_162700_1 2002.JOEQ01000057_gene7015 1.47e-40 149.0 COG3740@1|root,COG3740@2|Bacteria,2II2M@201174|Actinobacteria 201174|Actinobacteria S Phage prohead protease, HK97 family - - - - - - - - - - - - - k59_344793_1 1234888.K0A2J2_9VIRU 1.24e-103 320.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_344793_3 1234888.K0A2R8_9VIRU 1.83e-39 145.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_358170_1 291603.MREP_FBNY1 9.57e-08 53.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_164220_1 1588764.A0A0E3GD36_9VIRU 8.15e-15 79.0 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_127897_3 246196.MSMEI_6545 8.14e-28 107.0 arCOG05626@1|root,32V4D@2|Bacteria,2I38M@201174|Actinobacteria,23FBM@1762|Mycobacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_176525_2 1283079.M1HMA6_9CAUD 1.29e-27 113.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_152024_1 742733.HMPREF9469_05036 4.97e-43 145.0 2AIHK@1|root,318ZG@2|Bacteria,1V7P0@1239|Firmicutes,24KNU@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_6292_1 742733.HMPREF9469_05020 4.32e-74 253.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,221IX@1506553|Lachnoclostridium 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_200525_1 1795993.A0A140CTQ1_9CIRC 9.26e-45 160.0 4QB6C@10239|Viruses,4QUKM@29258|ssDNA viruses 10239|Viruses J Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_273408_2 1692248.A0A0K1RLN2_9CIRC 1.49e-88 273.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_287274_1 1507.HMPREF0262_02860 1.12e-13 79.7 COG0749@1|root,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,36EWE@31979|Clostridiaceae 186801|Clostridia L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_17156_1 40373.F991_01440 4.23e-11 61.6 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,3NRIW@468|Moraxellaceae 1236|Gammaproteobacteria L Single-strand binding protein family ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_334343_2 1618238.A0A0C5I2G8_9CIRC 2.43e-12 67.4 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_213418_1 219305.MCAG_02680 2.84e-53 187.0 COG4676@1|root,COG4676@2|Bacteria,2GPA6@201174|Actinobacteria,4DCBY@85008|Micromonosporales 201174|Actinobacteria S Protein conserved in bacteria - - - - - - - - - - - - - k59_238273_1 1122137.AQXF01000008_gene3450 5.92e-21 98.6 COG3914@1|root,COG3914@2|Bacteria 2|Bacteria O protein N-acetylglucosaminyltransferase activity - - - - - - - - - - - - Glyco_transf_41 k59_18677_1 1385658.U5KNR1_9VIRU 8.86e-58 193.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_18677_2 105154.Q9MBT9_9VIRU 1.28e-10 60.5 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_18677_3 1385658.U5KPZ6_9VIRU 1.94e-95 296.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_383862_1 1692257.A0A0K1RL39_9CIRC 4.86e-73 233.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_129618_1 429009.Adeg_2001 2.15e-32 124.0 COG3378@1|root,COG3378@2|Bacteria,1UIXP@1239|Firmicutes,25FUT@186801|Clostridia 186801|Clostridia L Bifunctional DNA primase polymerase - - - - - - - - - - - - PriCT_1,Prim-Pol k59_68821_1 1541960.KQ78_00464 8.04e-06 51.6 2DFHK@1|root,32U5H@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_80767_3 935261.JAGL01000009_gene1160 7.7e-06 51.2 2DUXE@1|root,32UY2@2|Bacteria,1N2YI@1224|Proteobacteria,2UEWK@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage T7 capsid assembly protein - - - - - - - - - - - - Phage_T7_Capsid k59_336365_1 863365.XHC_2843 1.14e-12 73.2 COG1511@1|root,COG2911@1|root,COG1511@2|Bacteria,COG2911@2|Bacteria,1QU6S@1224|Proteobacteria,1S7WY@1236|Gammaproteobacteria 1236|Gammaproteobacteria D tail tape measure protein - - - - - - - - - - - - SLT,Tape_meas_lam_C k59_238530_1 1215114.BBIU01000011_gene1684 1.1e-29 110.0 2DSAB@1|root,33F8C@2|Bacteria 2|Bacteria S Protein of unknown function (DUF3168) - - - - - - - - - - - - DUF3168 k59_300223_4 1609634.A0A0C5AFV4_9VIRU 6.43e-36 139.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_105097_1 1122992.CBQQ010000009_gene1840 4.42e-15 70.9 2C8RN@1|root,32RMQ@2|Bacteria,4NSD0@976|Bacteroidetes,2FVDC@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_348416_1 1265310.CCBD010000069_gene401 9.58e-19 86.3 COG0749@1|root,COG0749@2|Bacteria 2|Bacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_pol_A k59_252987_1 186617.M9M8L2_9VIRU 1.74e-47 167.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_302573_2 326297.Sama_0093 1.34e-08 61.6 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,2Q9N3@267890|Shewanellaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_277230_1 658187.LDG_7434 1.07e-27 111.0 28H9R@1|root,2Z7MD@2|Bacteria,1MVTR@1224|Proteobacteria,1RMPH@1236|Gammaproteobacteria,1JCHJ@118969|Legionellales 118969|Legionellales S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_314058_1 1054213.HMPREF9946_02225 9.98e-43 154.0 COG4695@1|root,COG4695@2|Bacteria,1PNB7@1224|Proteobacteria,2V9W5@28211|Alphaproteobacteria,2JY1F@204441|Rhodospirillales 204441|Rhodospirillales S Phage portal protein - - - - - - - - - - - - Phage_portal k59_350480_2 1211115.ALIQ01000188_gene637 0.000381 45.4 2E46I@1|root,32Z2G@2|Bacteria,1N9GR@1224|Proteobacteria,2UFE5@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_189111_1 1157943.KB892705_gene2039 5.13e-57 192.0 COG3969@1|root,COG3969@2|Bacteria,2H4MT@201174|Actinobacteria 201174|Actinobacteria S Phosphoadenosine phosphosulfate reductase family - - - - - - - - - - - - PAPS_reduct k59_204746_2 701347.Entcl_1845 2.5e-21 95.1 2CWYZ@1|root,32T0P@2|Bacteria,1MZEM@1224|Proteobacteria,1S9HP@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_204746_4 401526.TcarDRAFT_1278 1.58e-65 213.0 COG4422@1|root,COG4422@2|Bacteria,1TPP1@1239|Firmicutes,4H3G7@909932|Negativicutes 909932|Negativicutes S Protein of unknown function (DUF5131) - - - - - - - - - - - - DUF5131 k59_204746_6 1122146.AUHP01000009_gene838 3.34e-06 55.8 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4HA1S@91061|Bacilli,3F441@33958|Lactobacillaceae 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family sftA - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE,Ftsk_gamma k59_204746_7 880072.Desac_2401 0.000332 43.5 COG0863@1|root,COG0863@2|Bacteria,1R7RV@1224|Proteobacteria,42NFT@68525|delta/epsilon subdivisions,2WJMQ@28221|Deltaproteobacteria,2MRAU@213462|Syntrophobacterales 28221|Deltaproteobacteria L DNA methylase - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_326925_1 469596.HMPREF9488_03270 1.37e-13 71.2 COG0758@1|root,COG0758@2|Bacteria,1VNFT@1239|Firmicutes 1239|Firmicutes LU Protein of unknown function (DUF2493) - - - - - - - - - - - - DUF2493 k59_277481_1 1007096.BAGW01000014_gene1102 9.56e-18 82.8 COG0270@1|root,COG0270@2|Bacteria,1TR36@1239|Firmicutes,249XY@186801|Clostridia,2N7CV@216572|Oscillospiraceae 186801|Clostridia L C-5 cytosine-specific DNA methylase - - - - - - - - - - - - DNA_methylase k59_266331_1 1234888.K0A2J2_9VIRU 1.8e-49 174.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_376076_1 484770.UFO1_1695 7.14e-25 110.0 COG5525@1|root,COG5525@2|Bacteria,1TQBY@1239|Firmicutes,4H2HP@909932|Negativicutes 909932|Negativicutes S Phage terminase large subunit (GpA) - - - - - - - - - - - - Terminase_GpA k59_22651_1 1379713.S5SYD9_9CIRC 6.22e-29 114.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_190555_5 489825.LYNGBM3L_45140 6.4e-09 60.1 COG0241@1|root,COG0241@2|Bacteria,1G8EU@1117|Cyanobacteria,1HD16@1150|Oscillatoriales 1117|Cyanobacteria E Polynucleotide kinase 3 phosphatase - - 3.1.3.82,3.1.3.83 ko:K03273 ko00540,ko01100,map00540,map01100 M00064 R05647,R09771 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - - HAD_2,PNK3P k59_315893_2 1082932.ATCR1_06806 1.52e-13 81.3 COG3266@1|root,COG3266@2|Bacteria,1QZ8S@1224|Proteobacteria,2URTR@28211|Alphaproteobacteria,4BG0Y@82115|Rhizobiaceae 28211|Alphaproteobacteria M domain, Protein - - - - - - - - - - - - - k59_22936_2 63577.G9P6P8 3.86e-05 53.9 2CNC5@1|root,2QV54@2759|Eukaryota,39S8X@33154|Opisthokonta,3NW2N@4751|Fungi,3QMXN@4890|Ascomycota,211EZ@147550|Sordariomycetes,3TG8Z@5125|Hypocreales,3TWVF@5129|Hypocreaceae 4751|Fungi G Pectate lyase superfamily protein - - 3.2.1.58 ko:K01210 ko00500,map00500 - R00308,R03115 RC00467 ko00000,ko00001,ko01000 - - - Pectate_lyase_3 k59_376366_1 1609634.A0A0C5AFT2_9VIRU 7e-76 239.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_254899_1 1476391.X5KCC8_9CAUD 5.49e-56 196.0 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_254899_2 1540097.A0A0A0YPX0_9CAUD 6.49e-74 238.0 4QEG2@10239|Viruses,4QRJ9@28883|Caudovirales,4QP0R@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_254899_3 1173762.S4TP25_9CAUD 4.09e-34 132.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_388134_3 145579.REP_BPPHM 2.17e-34 135.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_388134_5 105154.Q9MBU6_9VIRU 4.3e-17 81.3 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_242755_1 1520935.A0A0H3UB63_9CIRC 1.84e-11 69.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_22952_1 1618248.A0A0C5IB82_9CIRC 8.71e-19 88.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388135_1 186617.M9M8L2_9VIRU 8.87e-09 56.6 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_121725_1 57119.REP_BEYDV 3.07e-12 75.1 4QB6C@10239|Viruses,4QUKM@29258|ssDNA viruses 10239|Viruses J Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_291796_1 314230.DSM3645_05250 7.16e-11 69.3 COG4968@1|root,COG4968@2|Bacteria,2J07S@203682|Planctomycetes 203682|Planctomycetes NU Pfam:N_methyl_2 - - - - - - - - - - - - N_methyl k59_328277_1 1498172.A0A0F6N5T0_9CAUD 5.59e-31 123.0 4QAIK@10239|Viruses,4QPEB@28883|Caudovirales,4QP3P@10744|Podoviridae 10744|Podoviridae S phosphoprotein phosphatase activity - - - - - - - - - - - - - k59_328277_2 1380355.JNIJ01000008_gene2003 9.38e-09 61.6 COG4974@1|root,COG4974@2|Bacteria,1QV9T@1224|Proteobacteria,2UBC9@28211|Alphaproteobacteria,3K26N@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Phage integrase family - - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k59_48877_1 471857.Svir_33880 4.09e-56 187.0 COG0451@1|root,COG0451@2|Bacteria,2GJJG@201174|Actinobacteria,4DYHF@85010|Pseudonocardiales 201174|Actinobacteria GM PFAM NAD dependent epimerase dehydratase family sqdB - 3.13.1.1 ko:K06118 ko00520,ko00561,map00520,map00561 - R05775 RC01469 ko00000,ko00001,ko01000 - - - Epimerase k59_73116_1 1692244.A0A0K1RLR5_9CIRC 7.31e-65 207.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_85269_1 1415146.V5Q8Q5_9CAUD 3.24e-65 228.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_133858_1 1298858.AUEL01000029_gene99 3.32e-11 62.0 COG3179@1|root,COG3179@2|Bacteria,1R71F@1224|Proteobacteria,2UD1N@28211|Alphaproteobacteria,43MAV@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S chitinase - - - - - - - - - - - - Glyco_hydro_19 k59_304009_2 1175306.GWL_33000 3.36e-30 119.0 COG2268@1|root,COG2268@2|Bacteria,1P39U@1224|Proteobacteria,2VMEW@28216|Betaproteobacteria 28216|Betaproteobacteria S prohibitin homologues - - - - - - - - - - - - Band_7 k59_194638_1 1463936.JOJI01000017_gene7342 5.13e-60 211.0 COG0210@1|root,COG0210@2|Bacteria,2GU9Z@201174|Actinobacteria 201174|Actinobacteria L UvrD-like helicase C-terminal domain - - - - - - - - - - - - AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2 k59_291799_1 691965.D4P7I3_9CAUD 2.26e-76 258.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_291799_2 428125.CLOLEP_01377 9.16e-07 49.3 2E0G5@1|root,32W28@2|Bacteria,1VAS0@1239|Firmicutes,24NYA@186801|Clostridia,3WNKT@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_60977_1 1408424.JHYI01000032_gene3843 8.21e-33 134.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,4H9Z7@91061|Bacilli,1ZEKP@1386|Bacillus 91061|Bacilli L DNA polymerase A domain - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_121729_2 1634485.A0A0E3JN85_9VIRU 6.25e-56 182.0 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_158274_2 759938.F5BSB4_9CIRC 1.37e-43 163.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_24792_4 192952.MM_0043 4.77e-05 55.8 COG3291@1|root,arCOG02496@1|root,arCOG02496@2157|Archaea,arCOG02507@2157|Archaea,arCOG02546@2157|Archaea,2Y7MW@28890|Euryarchaeota 2157|Archaea S Lactonase, 7-bladed beta-propeller - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - Baseplate_J,CARDB,Cellulase,HYR,NosD,PKD,PQQ_3,Polysacc_deac_1,VWA k59_12559_1 948071.S4S2D9_9CAUD 1.51e-241 688.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae 10744|Podoviridae S ribonucleoside-triphosphate reductase activity - - - - - - - - - - - - - k59_12559_5 1122137.AQXF01000002_gene208 3.41e-18 82.0 2E645@1|root,330T3@2|Bacteria,1NEGX@1224|Proteobacteria,2UJTA@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_49225_1 1609634.A0A0C5AFV4_9VIRU 8.55e-94 292.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_73521_1 1196031.ALEG01000004_gene4654 7.77e-32 125.0 COG4712@1|root,COG4712@2|Bacteria,1VENV@1239|Firmicutes,4HX6K@91061|Bacilli,1ZJDG@1386|Bacillus 91061|Bacilli S Rad52/22 family double-strand break repair protein - - - - - - - - - - - - Rad52_Rad22 k59_73521_2 643648.Slip_1905 9.83e-09 53.5 COG1551@1|root,COG1551@2|Bacteria,1VEEF@1239|Firmicutes,24QPD@186801|Clostridia,42K91@68298|Syntrophomonadaceae 186801|Clostridia J Could accelerate the degradation of some genes transcripts potentially through selective RNA binding csrA - - ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 - - - ko00000,ko00001,ko03019 - - - CsrA k59_122118_1 1385658.U5KPZ6_9VIRU 9.13e-24 102.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_61453_1 1177928.TH2_09534 4.86e-49 167.0 28HS3@1|root,2Z7ZE@2|Bacteria,1QH9A@1224|Proteobacteria,2TVB0@28211|Alphaproteobacteria,2JPPD@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_231399_4 1116232.AHBF01000066_gene8808 6.56e-15 72.0 2B4Q9@1|root,31XGJ@2|Bacteria,2IKKF@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_170524_1 1234888.K0A2J2_9VIRU 1.91e-66 221.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_329267_2 420662.Mpe_A3780 2.88e-12 75.5 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2VIG0@28216|Betaproteobacteria,1KKG2@119065|unclassified Burkholderiales 28216|Betaproteobacteria K Belongs to the ParB family parB - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_220232_2 76869.PputGB1_1746 2.09e-109 338.0 COG0507@1|root,COG0507@2|Bacteria,1R1AT@1224|Proteobacteria,1RS66@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Participates in initiation and elongation during chromosome replication - - - - - - - - - - - - - k59_232083_2 1385658.U5KPZ6_9VIRU 2.29e-209 598.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_353851_1 1609634.A0A0C5AFV4_9VIRU 3.72e-51 177.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_171347_1 1609634.A0A0C5AFV4_9VIRU 5.01e-131 391.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_171347_3 1609634.A0A0C5AFT2_9VIRU 1.39e-134 392.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_171347_7 1609634.A0A0C5ANA6_9VIRU 4.49e-20 91.3 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_378012_3 691965.D4P7E6_9CAUD 2.34e-08 66.6 4QAK6@10239|Viruses,4R01K@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_183114_12 273068.TTE0500 1.13e-12 72.8 COG0438@1|root,COG0438@2|Bacteria,1URHF@1239|Firmicutes,259DD@186801|Clostridia,42ITT@68295|Thermoanaerobacterales 186801|Clostridia M transferase activity, transferring glycosyl groups - - - - - - - - - - - - - k59_134771_2 1001530.BACE01000005_gene27 2e-17 84.0 COG1196@1|root,COG1196@2|Bacteria,1PPPK@1224|Proteobacteria,1TJ76@1236|Gammaproteobacteria,1Y0QY@135623|Vibrionales 135623|Vibrionales D nuclear chromosome segregation - - - - - - - - - - - - - k59_98499_1 1385658.U5KPZ6_9VIRU 8.33e-82 260.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_98499_3 1385658.U5KNR1_9VIRU 3.87e-69 226.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_293912_1 1283079.M1ID95_9CAUD 6.29e-49 187.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_63322_1 145579.CAPSD_BPPHM 2.82e-73 239.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_209229_1 1234888.K0A2J2_9VIRU 4.71e-47 169.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_354740_6 1234888.K0A2J2_9VIRU 4.21e-121 368.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_124086_1 637389.Acaty_c0101 2.38e-62 213.0 COG3378@1|root,COG3378@2|Bacteria,1MV7I@1224|Proteobacteria,1RRN5@1236|Gammaproteobacteria 1236|Gammaproteobacteria L D5 N terminal like - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,PriCT_1,PriCT_2,Toprim_2 k59_221332_1 986075.CathTA2_0705 1.16e-52 201.0 COG5280@1|root,COG5412@1|root,COG5280@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HAFE@91061|Bacilli 91061|Bacilli M Phage tail tape measure protein - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,SLT k59_63324_1 10855.CAPSD_SPV4 6.57e-10 62.4 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_124093_1 105154.Q9MBU3_9VIRU 5.77e-15 76.3 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_233102_3 34839.XP_005374168.1 3.63e-25 108.0 COG1088@1|root,KOG0747@2759|Eukaryota,39ADA@33154|Opisthokonta,3BF2W@33208|Metazoa,3CWS2@33213|Bilateria,484W4@7711|Chordata,4926F@7742|Vertebrata,3J8K7@40674|Mammalia,35B91@314146|Euarchontoglires,4Q0BM@9989|Rodentia 33208|Metazoa G Male sterility protein TGDS - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd k59_50932_1 1609634.A0A0C5AFV4_9VIRU 2.58e-61 205.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_196827_2 1232443.BAIA02000078_gene46 4.36e-15 84.7 COG2887@1|root,COG2887@2|Bacteria,1TPIC@1239|Firmicutes,247TB@186801|Clostridia 186801|Clostridia L Psort location Cytoplasmic, score - - - - - - - - - - - - DUF2800 k59_2306_1 1385658.U5KPZ6_9VIRU 2.16e-33 130.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_100648_1 1122137.AQXF01000002_gene217 9.23e-06 53.9 COG3064@1|root,COG3064@2|Bacteria,1NQ5T@1224|Proteobacteria,2UK7G@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Membrane - - - - - - - - - - - - PTR k59_64375_1 491916.RHECIAT_CH0000838 1.24e-12 71.2 COG1861@1|root,COG1861@2|Bacteria,1RG42@1224|Proteobacteria,2UABZ@28211|Alphaproteobacteria,4BEAT@82115|Rhizobiaceae 28211|Alphaproteobacteria M Cytidylyltransferase - - - ko:K07257 - - - - ko00000 - - - CTP_transf_3 k59_270457_1 1609634.A0A0C5AFT2_9VIRU 3.2e-40 142.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_3602_1 1096546.WYO_0201 2.77e-35 137.0 28P6A@1|root,2ZC10@2|Bacteria,1RBZE@1224|Proteobacteria,2UQEG@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_76185_1 1479238.JQMZ01000001_gene1159 3.38e-35 137.0 COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,43WIM@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_270459_1 80637.XP_007771213.1 2.2e-08 63.2 COG0749@1|root,COG2272@1|root,KOG1516@2759|Eukaryota,KOG3657@2759|Eukaryota,38B9M@33154|Opisthokonta,3NTXD@4751|Fungi,3UYZN@5204|Basidiomycota,2283A@155619|Agaricomycetes 4751|Fungi L DNA polymerase A domain MIP1 GO:0000002,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006264,GO:0006725,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0032042,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02332 ko01100,ko04139,map01100,map04139 M00294 - - ko00000,ko00001,ko00002,ko01000,ko03029,ko03032 - - - DNA_pol_A k59_210320_1 665956.HMPREF1032_00686 7.3e-50 193.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,3WN92@541000|Ruminococcaceae 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_88628_3 1385658.U5KNR1_9VIRU 4.7e-31 122.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_331903_1 1618258.A0A0C5I9K3_9CIRC 1.24e-15 85.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_258553_1 1618241.A0A0C5I2I4_9CIRC 1.6e-74 233.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_367659_2 1618251.A0A0C5I2L8_9CIRC 6.49e-80 251.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_343602_1 1144310.PMI07_002360 1.74e-08 61.6 2DPZ1@1|root,3340X@2|Bacteria,1R2EE@1224|Proteobacteria,2TZIB@28211|Alphaproteobacteria,4BP2Q@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_125339_1 570952.ATVH01000019_gene771 1.93e-52 190.0 COG3170@1|root,COG3170@2|Bacteria,1Q45C@1224|Proteobacteria,2U08F@28211|Alphaproteobacteria 28211|Alphaproteobacteria NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - k59_173672_1 1385658.U5KPZ6_9VIRU 1.07e-68 227.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_39629_1 634504.Bgr_07970 3.39e-56 192.0 28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria,2U265@28211|Alphaproteobacteria,48TMW@772|Bartonellaceae 28211|Alphaproteobacteria S to expressed protein Bartonella henselae str. Houston-1 gi 49238873 emb CAF28166.1 - - - - - - - - - - - - DUF4043 k59_198775_1 1165094.RINTHH_3920 2.08e-65 213.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_15655_3 1385658.U5KPZ6_9VIRU 2.92e-104 322.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_162513_2 1236000.L0ASJ4_9CAUD 6.97e-06 51.2 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QI9F@10662|Myoviridae 10662|Myoviridae S Type III restriction enzyme, res subunit - - - - - - - - - - - - - k59_308455_1 1537917.JU82_00020 2.44e-50 170.0 COG0553@1|root,COG0553@2|Bacteria,1PM15@1224|Proteobacteria,42ZGS@68525|delta/epsilon subdivisions,2YS8B@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria L DEAD-like helicases superfamily - - - - - - - - - - - - - k59_308461_2 105154.Q9MBU6_9VIRU 3.49e-30 122.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_89784_1 260827.Q6R6A4_9CAUD 5.11e-17 87.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales 28883|Caudovirales S N-methyltransferase activity - - - - - - - - - - - - - k59_138068_3 713587.THITH_04235 2.61e-25 110.0 COG4424@1|root,COG4424@2|Bacteria,1N77D@1224|Proteobacteria,1SB49@1236|Gammaproteobacteria,1WZDB@135613|Chromatiales 135613|Chromatiales S PFAM sulfotransferase - - - - - - - - - - - - Sulfotransfer_3 k59_138068_4 1038858.AXBA01000002_gene3749 2.45e-20 83.6 294NR@1|root,2ZS22@2|Bacteria,1P6AD@1224|Proteobacteria,2UWFS@28211|Alphaproteobacteria,3F24E@335928|Xanthobacteraceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_211677_1 1219035.NT2_13_00580 3.41e-33 130.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_213284_2 626887.J057_01685 3.75e-60 196.0 28HS3@1|root,2Z7ZE@2|Bacteria,1QH9A@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_30644_1 105154.Q9MBU6_9VIRU 2.12e-30 120.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_273316_1 551789.ATVJ01000001_gene1244 1.47e-08 58.2 COG2304@1|root,COG2304@2|Bacteria,1RBVD@1224|Proteobacteria,2UQGF@28211|Alphaproteobacteria,43XCY@69657|Hyphomonadaceae 28211|Alphaproteobacteria S von Willebrand factor (vWF) type A domain - - - - - - - - - - - - VWA k59_273318_1 1211640.K4JUV4_9CAUD 3.81e-41 143.0 4QC3Q@10239|Viruses,4QVEE@35237|dsDNA viruses no RNA stage,4QPSH@28883|Caudovirales 28883|Caudovirales S Protein of unknown function DUF262 - - - - - - - - - - - - - k59_127808_1 637390.AFOH01000111_gene2829 5.77e-06 48.1 COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,1S8RG@1236|Gammaproteobacteria,2NCAQ@225057|Acidithiobacillales 225057|Acidithiobacillales M Belongs to the ompA family - - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA k59_127808_2 1317122.ATO12_16480 1.32e-25 105.0 COG0600@1|root,COG0600@2|Bacteria,4NPPC@976|Bacteroidetes,1IIYV@117743|Flavobacteriia,2YK3B@290174|Aquimarina 976|Bacteroidetes P Binding-protein-dependent transport system inner membrane component - - - ko:K02050,ko:K15577 ko00910,ko02010,map00910,map02010 M00188,M00438 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16,3.A.1.16.1,3.A.1.16.2,3.A.1.17 - - BPD_transp_1 k59_151908_1 1280944.HY17_04705 2.72e-10 69.3 2E8SI@1|root,3333B@2|Bacteria,1N7MG@1224|Proteobacteria,2UJSF@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_67214_1 856793.MICA_990 1e-35 132.0 COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2TT5T@28211|Alphaproteobacteria,4BQCW@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB - 4.2.1.46,4.2.1.76,5.1.3.2 ko:K01710,ko:K01784,ko:K12450 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 M00361,M00362,M00632,M00793 R00291,R00293,R02984,R06513 RC00289,RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd k59_67214_2 247639.MGP2080_05417 1.28e-23 97.1 COG4627@1|root,COG4627@2|Bacteria,1N2HA@1224|Proteobacteria,1SJB1@1236|Gammaproteobacteria 1236|Gammaproteobacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Methyltransf_11 k59_128041_2 49964.Q94MV0_9CAUD 1.76e-16 85.5 4QCMA@10239|Viruses,4QZ56@35237|dsDNA viruses no RNA stage,4QSFV@28883|Caudovirales,4QNWQ@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_139911_1 478749.BRYFOR_08534 1.9e-76 261.0 28JED@1|root,2Z98K@2|Bacteria,1TW1U@1239|Firmicutes,24CFD@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - GerE k59_382652_1 1555208.A0A097EW01_9CAUD 3.34e-36 145.0 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - GO:0008150,GO:0044403,GO:0044409,GO:0044411,GO:0044419,GO:0051701,GO:0051704,GO:0051828,GO:0051830,GO:0085027 - - - - - - - - - - - k59_334473_1 243233.MCA2929 1.03e-11 70.1 2EPTJ@1|root,33HE3@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_225401_1 679197.HMPREF9336_02247 4.35e-25 107.0 COG0749@1|root,COG0749@2|Bacteria,2I975@201174|Actinobacteria 201174|Actinobacteria L COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_pol_A,DNA_pol_A_exo1 k59_225401_2 205870.Q857H3_BPMB2 2.43e-10 63.2 4QCVA@10239|Viruses,4QXZJ@35237|dsDNA viruses no RNA stage,4QQHQ@28883|Caudovirales,4QMJC@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_346489_1 745776.DGo_CA1997 3.48e-06 57.8 COG2152@1|root,COG2152@2|Bacteria 2|Bacteria G transferase activity, transferring glycosyl groups - - - - - - - - - - - - CHU_C,Laminin_G_3 k59_359267_1 889338.G3BLT4_9CAUD 7.37e-05 55.8 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QJCH@10662|Myoviridae 10662|Myoviridae S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_359267_4 411460.RUMTOR_01350 4.64e-11 63.5 2EAAT@1|root,334F2@2|Bacteria,1VJJI@1239|Firmicutes,24TQU@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_104633_1 669262.COK_1006 3.48e-28 114.0 COG0582@1|root,COG0582@2|Bacteria,1NWGS@1224|Proteobacteria,1S5J8@1236|Gammaproteobacteria,1Y79G@135625|Pasteurellales 135625|Pasteurellales L Phage integrase family - - - - - - - - - - - - Phage_integrase k59_165450_1 1122599.AUGR01000011_gene4011 2.33e-33 136.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1QZAD@1224|Proteobacteria,1RYP3@1236|Gammaproteobacteria,1XMG9@135619|Oceanospirillales 135619|Oceanospirillales D nuclear chromosome segregation - - - - - - - - - - - - - k59_93264_1 1385658.U5KPZ6_9VIRU 4.57e-68 225.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_383605_1 381666.H16_A2480 5.09e-172 498.0 COG3843@1|root,COG3843@2|Bacteria,1QZ0Y@1224|Proteobacteria,2VTP0@28216|Betaproteobacteria,1KBC9@119060|Burkholderiaceae 28216|Betaproteobacteria U MobA/MobL family - - - - - - - - - - - - MobA_MobL k59_80473_1 1692242.A0A0K1RKZ2_9CIRC 2.93e-22 102.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_187125_1 743974.MBO_05569 4.47e-10 64.7 COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,1S8R3@1236|Gammaproteobacteria,3NSWJ@468|Moraxellaceae 1236|Gammaproteobacteria M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - - - - - - - - - - SLT,Sel1 k59_55994_1 1234888.K0A2J2_9VIRU 1.8e-64 216.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_371608_1 1005995.GTPT_1612 9.25e-23 93.2 COG1403@1|root,COG1403@2|Bacteria,1PSJS@1224|Proteobacteria,1TC4G@1236|Gammaproteobacteria,4BVT4@82986|Tatumella 1236|Gammaproteobacteria V Bacteriophage Lambda NinG protein - - - - - - - - - - - - NinG k59_276071_1 387092.NIS_1675 1.08e-06 59.3 COG1061@1|root,COG1061@2|Bacteria,1PPY3@1224|Proteobacteria,43AP9@68525|delta/epsilon subdivisions 1224|Proteobacteria L SNF2 family N-terminal domain - - - - - - - - - - - - ERCC3_RAD25_C,Helicase_C,PLDc_2,ResIII k59_349325_1 691965.D4P7I3_9CAUD 1.59e-135 423.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_239396_1 1122599.AUGR01000001_gene288 9.59e-47 157.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,1SQ0T@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_203259_1 257313.BP3359 1.77e-07 51.2 2EK5N@1|root,33DW2@2|Bacteria,1NHDG@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_290118_2 440250.A5HL26_9CAUD 3.15e-19 95.1 4QBD3@10239|Viruses,4QXFU@35237|dsDNA viruses no RNA stage,4QQ7Z@28883|Caudovirales,4QNJ0@10744|Podoviridae 10744|Podoviridae S P22 coat protein - gene protein 5 - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0009987,GO:0016032,GO:0016043,GO:0019012,GO:0019028,GO:0019030,GO:0019058,GO:0019068,GO:0019069,GO:0019075,GO:0022607,GO:0039620,GO:0042802,GO:0042803,GO:0044085,GO:0044403,GO:0044419,GO:0044423,GO:0046729,GO:0046797,GO:0046983,GO:0051704,GO:0071840 - - - - - - - - - - - k59_216321_3 298655.KI912266_gene3165 0.000892 43.5 COG0372@1|root,COG0372@2|Bacteria,2GM3G@201174|Actinobacteria 201174|Actinobacteria C Citrate synthase - - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt,HTH_17 k59_19675_2 411460.RUMTOR_01342 1.01e-79 245.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_312664_1 285514.JNWO01000076_gene385 4.07e-44 157.0 2CDQ7@1|root,2Z7KV@2|Bacteria,2IDCC@201174|Actinobacteria 201174|Actinobacteria S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_276081_1 1187851.A33M_3329 1.77e-29 119.0 2C5GI@1|root,2Z8C1@2|Bacteria,1R8XM@1224|Proteobacteria,2TUME@28211|Alphaproteobacteria 28211|Alphaproteobacteria S P22 coat protein - gene protein 5 - - - - - - - - - - - - P22_CoatProtein k59_301169_1 670292.JH26_14575 8.57e-86 270.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TTEX@28211|Alphaproteobacteria,1JX4E@119045|Methylobacteriaceae 28211|Alphaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_349334_1 1476902.A0A067ZJA1_9CAUD 5.09e-52 188.0 4QAXX@10239|Viruses,4QV9W@35237|dsDNA viruses no RNA stage,4QPTB@28883|Caudovirales,4QHV2@10662|Myoviridae 10662|Myoviridae S Phage terminase large subunit (GpA) - - - - - - - - - - - - - k59_325534_1 1123269.NX02_04445 1.43e-16 80.5 2EK9X@1|root,33E07@2|Bacteria,1NP0D@1224|Proteobacteria,2UJQX@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_239526_1 1380894.S5TR92_9CIRC 5.15e-34 132.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_82087_1 1609634.A0A0C5AFV4_9VIRU 3.96e-179 515.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_327239_1 478749.BRYFOR_08535 7.77e-32 118.0 29YRZ@1|root,30KMY@2|Bacteria,1V4Y4@1239|Firmicutes,24HPY@186801|Clostridia 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - DUF2800 k59_327239_2 475178.B2BTN9_9CAUD 4.58e-16 82.8 4QB9J@10239|Viruses,4QXFE@35237|dsDNA viruses no RNA stage,4QS1Z@28883|Caudovirales,4QN8F@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_362282_1 521674.Plim_4253 2.06e-73 242.0 COG4653@1|root,COG4653@2|Bacteria,2J4NE@203682|Planctomycetes 203682|Planctomycetes S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_230169_1 1131814.JAFO01000001_gene2083 1.32e-61 209.0 COG0507@1|root,COG5362@1|root,COG0507@2|Bacteria,COG5362@2|Bacteria,1R90H@1224|Proteobacteria,2U236@28211|Alphaproteobacteria 28211|Alphaproteobacteria L TIGRFAM Phage - - - - - - - - - - - - Terminase_6 k59_168315_1 946235.CAER01000025_gene897 3.34e-39 160.0 COG3378@1|root,COG3378@2|Bacteria,1TQP9@1239|Firmicutes,4I492@91061|Bacilli,23MDS@182709|Oceanobacillus 91061|Bacilli S Phage plasmid primase, P4 family - - - - - - - - - - - - D5_N k59_277799_1 1235689.K4NWZ9_9CAUD 5.51e-12 65.9 4QB0C@10239|Viruses,4QW7S@35237|dsDNA viruses no RNA stage,4QPK3@28883|Caudovirales,4QNHV@10744|Podoviridae 10744|Podoviridae S Endodeoxyribonuclease RusA - - - - - - - - - - - - - k59_386636_2 1692249.A0A0K1RLN8_9CIRC 1.27e-43 154.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_241364_1 1121440.AUMA01000014_gene1949 3.94e-07 51.2 COG3935@1|root,COG3935@2|Bacteria,1P1RD@1224|Proteobacteria,431QE@68525|delta/epsilon subdivisions,2WXDK@28221|Deltaproteobacteria,2MC76@213115|Desulfovibrionales 28221|Deltaproteobacteria L DnaD domain protein - - - - - - - - - - - - - k59_314724_1 1123255.JHYS01000027_gene1746 1.28e-36 150.0 COG1040@1|root,COG1040@2|Bacteria,1QV41@1224|Proteobacteria,2VMZ1@28216|Betaproteobacteria,4AB0B@80864|Comamonadaceae 28216|Betaproteobacteria FL competence protein - - - - - - - - - - - - - k59_386790_1 1526550.A0A088F6W1_9VIRU 1.3e-24 108.0 4QAK6@10239|Viruses 10239|Viruses S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_35536_1 1385658.U5KPZ6_9VIRU 2.56e-38 142.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_253751_1 642227.HA49_08550 1.77e-09 57.8 2BVDA@1|root,30YKI@2|Bacteria,1PKH2@1224|Proteobacteria,1TJIJ@1236|Gammaproteobacteria,4BVW8@82986|Tatumella 1236|Gammaproteobacteria S DNA-packaging protein gp3 - - - - - - - - - - - - GP3_package k59_253751_2 1123405.AUMM01000017_gene2712 1.94e-45 159.0 COG1783@1|root,COG1783@2|Bacteria,1TRQP@1239|Firmicutes,4HDMY@91061|Bacilli 91061|Bacilli L Phage terminase, large subunit yqaT - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_71788_4 1445859.W6E9J9_9CAUD 4.97e-26 100.0 4QB6G@10239|Viruses,4QVYX@35237|dsDNA viruses no RNA stage,4QQS8@28883|Caudovirales 28883|Caudovirales S Peptidase M15 - - - - - - - - - - - - - k59_119634_2 1234888.K0A2J2_9VIRU 2.89e-80 255.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_254959_1 1234888.K0A2J2_9VIRU 1.37e-49 174.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_23026_1 1123487.KB892865_gene1388 2.03e-35 142.0 COG3378@1|root,COG3378@2|Bacteria 2|Bacteria KL Phage plasmid primase P4 family - - - ko:K06919 - - - - ko00000 - - - PriCT_2,Prim-Pol k59_11881_3 445686.E3SL62_9CAUD 1.26e-10 64.7 4QBAK@10239|Viruses,4QY34@35237|dsDNA viruses no RNA stage,4QQBQ@28883|Caudovirales,4QIQI@10662|Myoviridae 10662|Myoviridae S Bacteriophage T4-like capsid assembly protein (Gp20) - GO:0005575,GO:0019012 - - - - - - - - - - - k59_121019_1 1536592.A0A088FB34_9VIRU 5.68e-21 94.7 4QDKA@10239|Viruses 10239|Viruses S nuclease activity - - - - - - - - - - - - - k59_23038_1 691965.D4P7I3_9CAUD 7.8e-112 358.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_266507_2 67281.JNZZ01000024_gene4713 1.56e-79 270.0 COG0467@1|root,COG3378@1|root,COG0467@2|Bacteria,COG3378@2|Bacteria,2H1DT@201174|Actinobacteria 201174|Actinobacteria T Phage plasmid primase, P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N,DUF3854,Pox_D5,PriCT_1,Prim-Pol k59_266507_3 270374.MELB17_09208 2.33e-80 277.0 COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,1SN4D@1236|Gammaproteobacteria 1236|Gammaproteobacteria KL SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_266507_5 1005994.GTGU_01505 3.21e-34 142.0 COG0270@1|root,COG0338@1|root,COG0270@2|Bacteria,COG0338@2|Bacteria,1MV9H@1224|Proteobacteria,1RPSH@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase,MethyltransfD12 k59_266507_15 765698.Mesci_3835 2.31e-85 276.0 COG5323@1|root,COG5323@2|Bacteria,1R049@1224|Proteobacteria 1224|Proteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6 k59_266507_47 1236573.K4LRR0_9CAUD 2.4e-10 66.6 4QBFR@10239|Viruses,4QV1E@35237|dsDNA viruses no RNA stage,4QPRX@28883|Caudovirales,4QKMP@10699|Siphoviridae 10699|Siphoviridae S ERF superfamily - - - - - - - - - - - - - k59_266507_53 1191380.J7I4J7_9CAUD 4.88e-25 100.0 4QB0C@10239|Viruses,4QW7S@35237|dsDNA viruses no RNA stage,4QPK3@28883|Caudovirales,4QKQC@10699|Siphoviridae 10699|Siphoviridae S magnesium ion binding - - - - - - - - - - - - - k59_121315_2 1304275.C41B8_05368 1.59e-118 378.0 28S81@1|root,2ZEJD@2|Bacteria,1RCNN@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_61960_6 1234664.AMRO01000024_gene1822 6.64e-13 77.4 28K55@1|root,2Z9TX@2|Bacteria,1V0P7@1239|Firmicutes,4HEFY@91061|Bacilli,1WEQM@129337|Geobacillus 91061|Bacilli S Siphovirus ReqiPepy6 Gp37-like protein - - - - - - - - - - - - Sipho_Gp37 k59_1050_2 1095772.CAHH01000063_gene639 2.3e-28 111.0 2EES9@1|root,338JX@2|Bacteria,2H5MY@201174|Actinobacteria 201174|Actinobacteria L RNase_H superfamily - - - - - - - - - - - - RNase_H_2 k59_329124_1 1609634.A0A0C5AFV4_9VIRU 1.88e-109 336.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_219955_2 1692252.A0A0K1RL35_9CIRC 2.46e-90 278.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_304850_1 1439940.BAY1663_02356 4.22e-58 192.0 COG5449@1|root,COG5449@2|Bacteria 2|Bacteria S Phage conserved hypothetical protein BR0599 - - - - - - - - - - - - DUF2163,Phage_BR0599 k59_243887_1 313628.LNTAR_16448 1.33e-10 68.9 COG2425@1|root,COG2425@2|Bacteria 2|Bacteria S positive regulation of ATPase activity - - - - - - - - - - - - VWA_2,VWA_CoxE k59_353567_3 1609634.A0A0C5ANA6_9VIRU 8.04e-26 107.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_353567_5 105154.Q9MBU6_9VIRU 1.73e-52 181.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_365301_3 1385658.U5KPZ6_9VIRU 4.23e-63 210.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_12927_1 186617.M9M8L2_9VIRU 8.33e-82 260.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_341119_6 1214101.BN159_7423 2.74e-05 50.1 COG3023@1|root,COG3023@2|Bacteria,2I319@201174|Actinobacteria 201174|Actinobacteria V N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2,PG_binding_1 k59_341119_8 398720.MED217_18361 6.09e-09 54.7 COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,1I54R@117743|Flavobacteriia,2XJPE@283735|Leeuwenhoekiella 976|Bacteroidetes U mttA/Hcf106 family tatA - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 k59_25403_1 1234888.K0A2J2_9VIRU 8.78e-51 177.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_365428_1 1041147.AUFB01000007_gene642 1.62e-42 153.0 COG3567@1|root,COG3567@2|Bacteria,1QNPU@1224|Proteobacteria,2U19C@28211|Alphaproteobacteria,4BA7J@82115|Rhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1073) - - - ko:K09961 - - - - ko00000 - - - DUF1073 k59_220120_1 1161935.H9D1F0_9CAUD 1.97e-17 86.7 4QFN3@10239|Viruses,4QZSZ@35237|dsDNA viruses no RNA stage,4QQ4M@28883|Caudovirales,4QNXC@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_292835_1 1089115.G8I6P9_9CAUD 1.88e-08 62.4 4QUP9@35237|dsDNA viruses no RNA stage,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_317174_1 1379707.S5T672_9CIRC 3.03e-14 75.1 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_317174_2 1475143.W8SNN0_9CIRC 1.2e-28 117.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_342262_1 1331060.RLDS_11480 2.56e-29 114.0 COG0175@1|root,COG0175@2|Bacteria,1QZJ1@1224|Proteobacteria,2U233@28211|Alphaproteobacteria 28211|Alphaproteobacteria EH sulfate reduction - - - - - - - - - - - - - k59_221245_1 105154.Q9MBU6_9VIRU 1.08e-104 321.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_196720_1 172088.AUGA01000071_gene7567 4.23e-14 78.6 COG3740@1|root,COG3740@2|Bacteria,1QVIJ@1224|Proteobacteria,2TVIM@28211|Alphaproteobacteria,3K0XM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Caudovirus prohead serine protease - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_209119_2 291607.MREP_SCSVF 3.69e-15 81.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_282399_1 1276220.STAIW_v1c09600 0.000411 48.1 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,3WT2S@544448|Tenericutes 544448|Tenericutes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A k59_306085_6 1234888.K0A2J2_9VIRU 2.24e-158 465.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_306085_7 1385658.U5KNR1_9VIRU 4.3e-06 54.3 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_244972_2 1379717.S5SY19_9CIRC 2.42e-59 198.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_13639_1 1540097.A0A0A0YRN0_9CAUD 2.6e-146 441.0 4QF3C@10239|Viruses,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_26431_1 1220601.L7TQW5_9CAUD 5.67e-15 80.1 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales 28883|Caudovirales S DNA-dependent RNA polymerase - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_38437_1 1408422.JHYF01000002_gene2313 1.97e-19 99.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,36EWE@31979|Clostridiaceae 186801|Clostridia L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_13643_1 40041.SZO_04860 5.61e-13 74.3 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4H9WA@91061|Bacilli,1M9B1@119603|Streptococcus dysgalactiae group 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family ftsK GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k59_209144_2 322855.Q52PN3_9CAUD 2.73e-39 135.0 4QD4R@10239|Viruses,4QUPD@35237|dsDNA viruses no RNA stage,4QTAJ@28883|Caudovirales 28883|Caudovirales S Protein of unknown function (DUF3268) - - - - - - - - - - - - - k59_318451_1 866771.HMPREF9296_1126 3.22e-11 65.5 COG4422@1|root,COG4422@2|Bacteria,4NJKJ@976|Bacteroidetes,2FNM4@200643|Bacteroidia 976|Bacteroidetes S Bacteriophage protein gp37 - - - - - - - - - - - - DUF5131 k59_99371_1 1692252.A0A0K1RL35_9CIRC 2.93e-61 204.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_135784_1 1609634.A0A0C5AFV4_9VIRU 9.93e-99 307.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_161668_1 439375.Oant_0230 3.04e-69 221.0 COG0270@1|root,COG0270@2|Bacteria,1R5MR@1224|Proteobacteria,2U53Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_64604_1 1123508.JH636445_gene6801 1.07e-09 58.9 COG0629@1|root,COG0629@2|Bacteria,2IZJ8@203682|Planctomycetes 203682|Planctomycetes L Single-stranded DNA-binding protein ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_210551_2 1618258.A0A0C5I9K3_9CIRC 1.09e-17 91.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_246505_2 1609634.A0A0C5AFV4_9VIRU 4.2e-245 689.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_246505_3 1609634.A0A0C5ANA6_9VIRU 1.06e-22 98.6 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_246505_9 1609634.A0A0C5AFT2_9VIRU 9.66e-114 339.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_234504_1 1161935.H9D1F0_9CAUD 2.27e-15 79.7 4QFN3@10239|Viruses,4QZSZ@35237|dsDNA viruses no RNA stage,4QQ4M@28883|Caudovirales,4QNXC@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_234504_6 188350.Q8H9U7_9CAUD 5.54e-84 275.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_234504_7 649754.HMPREF0281_01830 5.2e-05 50.4 COG0749@1|root,COG4643@1|root,COG0749@2|Bacteria,COG4643@2|Bacteria,2I36D@201174|Actinobacteria,22MKB@1653|Corynebacteriaceae 201174|Actinobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_pol_A,DUF3854,Prim-Pol k59_234504_9 1283078.M1IPK2_9CAUD 1.49e-112 352.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_234504_11 1054968.G0X535_9CAUD 2.6e-27 122.0 4QB4B@10239|Viruses,4QWC6@35237|dsDNA viruses no RNA stage,4QQNI@28883|Caudovirales,4QNPA@10744|Podoviridae 10744|Podoviridae S Glutamine amidotransferase domain - - - - - - - - - - - - - k59_234504_12 1141137.K4F6X6_9CAUD 9.84e-16 84.7 4QFSQ@10239|Viruses,4R063@35237|dsDNA viruses no RNA stage,4QT6M@28883|Caudovirales,4QP2G@10744|Podoviridae 10744|Podoviridae S ligase activity - - - - - - - - - - - - - k59_112900_2 679197.HMPREF9336_02239 9.05e-17 77.0 2EI48@1|root,33BVK@2|Bacteria,2GZ85@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_210710_2 1411685.U062_00592 8.17e-76 244.0 2EW57@1|root,33PIB@2|Bacteria,1NQQA@1224|Proteobacteria,1SMVX@1236|Gammaproteobacteria,1J7VZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Phage replication protein CRI - - - - - - - - - - - - Phage_CRI k59_138212_2 1234888.K0A2J2_9VIRU 1.94e-170 496.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_138212_3 1234888.K0A2R8_9VIRU 1.23e-63 209.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_308660_1 1335760.ASTG01000033_gene58 2.94e-07 59.3 29WX1@1|root,30IJ2@2|Bacteria,1NHWP@1224|Proteobacteria,2VGT1@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_185535_3 1046714.AMRX01000006_gene3162 1.8e-25 101.0 2CC49@1|root,2ZBQQ@2|Bacteria,1RA92@1224|Proteobacteria,1S3BM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF1367) - - - - - - - - - - - - DUF1367 k59_185535_4 926569.ANT_21890 6.01e-21 91.3 COG1796@1|root,COG1796@2|Bacteria 2|Bacteria L DNA-directed DNA polymerase activity polX - - ko:K02347,ko:K04477 - - - - ko00000,ko03400 - - - DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP k59_5118_1 688245.CtCNB1_3556 9.05e-05 50.4 COG3391@1|root,COG3391@2|Bacteria,1MXN7@1224|Proteobacteria,2VWQ2@28216|Betaproteobacteria,4AFKK@80864|Comamonadaceae 28216|Betaproteobacteria S Putative phage tail protein - - - - - - - - - - - - Phage-tail_3 k59_16114_1 1161935.H9D1E7_9CAUD 7.74e-97 307.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_163003_1 1499967.BAYZ01000197_gene3021 1.79e-75 254.0 2DSKR@1|root,33GIU@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - RepB_primase k59_126674_1 1195073.I6XKW3_9CAUD 1.15e-18 91.7 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNBD@10744|Podoviridae 10744|Podoviridae S outer membrane - - - - - - - - - - - - - k59_296581_1 1122201.AUAZ01000017_gene2960 4.74e-231 654.0 COG5362@1|root,COG5362@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Terminase_6C k59_41100_1 1120985.AUMI01000001_gene2158 1.42e-21 98.6 COG3299@1|root,COG3299@2|Bacteria,1TQXP@1239|Firmicutes,4H5RU@909932|Negativicutes 909932|Negativicutes S Baseplate J-like protein - - - - - - - - - - - - Baseplate_J k59_272050_1 1122179.KB890417_gene3273 8.57e-40 149.0 COG2425@1|root,COG2425@2|Bacteria 2|Bacteria S positive regulation of ATPase activity rsr - - ko:K11089 ko05322,map05322 - - - ko00000,ko00001 - - - TROVE,VWA_CoxE k59_308862_3 679935.Alfi_2709 3.38e-26 109.0 COG4373@1|root,COG4373@2|Bacteria,4NI4T@976|Bacteroidetes,2FNH0@200643|Bacteroidia 976|Bacteroidetes S Mu-like prophage FluMu protein gp28 - - - - - - - - - - - - - k59_381563_1 1234888.K0A2J2_9VIRU 3.96e-56 191.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_185538_3 543632.JOJL01000029_gene3700 9.28e-07 55.5 COG0467@1|root,COG0467@2|Bacteria,2H1FN@201174|Actinobacteria,4DMU6@85008|Micromonosporales 201174|Actinobacteria T Bifunctional DNA primase/polymerase, N-terminal - - - - - - - - - - - - Prim-Pol k59_272055_2 1395587.P364_0122165 4.05e-11 65.1 COG2887@1|root,COG2887@2|Bacteria,1TPIC@1239|Firmicutes,4HCNN@91061|Bacilli,26S2A@186822|Paenibacillaceae 91061|Bacilli L Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_235592_1 1122604.JONR01000013_gene3288 2.54e-15 87.4 COG2931@1|root,COG2931@2|Bacteria,1NEBQ@1224|Proteobacteria,1SFX0@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Right handed beta helix region - - - - - - - - - - - - Beta_helix k59_29550_1 329726.AM1_2899 3.03e-18 89.0 2C6N9@1|root,32RHI@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - PDDEXK_1 k59_65915_1 105154.Q9MBU0_9VIRU 2.84e-39 143.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_212060_2 679935.Alfi_0779 1.76e-33 122.0 COG3023@1|root,COG3023@2|Bacteria,4PK0G@976|Bacteroidetes,2G1JR@200643|Bacteroidia,22VK1@171550|Rikenellaceae 976|Bacteroidetes V N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2 k59_6488_3 105154.Q9MBU6_9VIRU 1.33e-123 375.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_322680_1 349741.Amuc_1819 7.15e-30 123.0 28I8X@1|root,2Z8BQ@2|Bacteria,46V28@74201|Verrucomicrobia,2IVQE@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - k59_164436_2 478749.BRYFOR_08522 1.54e-61 204.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_128171_1 1788442.A0A190WH98_9CIRC 3.91e-12 72.8 4QB6C@10239|Viruses,4QUKM@29258|ssDNA viruses 10239|Viruses J Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_128172_1 595537.Varpa_2028 1.4e-14 78.6 COG4675@1|root,COG5295@1|root,COG4675@2|Bacteria,COG5295@2|Bacteria,1P3I0@1224|Proteobacteria 1224|Proteobacteria UW Hep Hag repeat protein - - - - - - - - - - - - - k59_186432_1 1609634.A0A0C5AFT2_9VIRU 0.000259 44.7 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_79321_1 13690.CP98_04983 4.05e-12 65.9 29WB4@1|root,30HWN@2|Bacteria,1PDVG@1224|Proteobacteria,2VDTZ@28211|Alphaproteobacteria,2KBWY@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - k59_79321_2 691965.D4P7C3_9CAUD 5.57e-41 139.0 4QDCX@10239|Viruses,4R0GS@35237|dsDNA viruses no RNA stage,4QS3P@28883|Caudovirales,4QKU8@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_79322_1 216594.MMAR_4828 2.45e-09 63.5 2EP1Y@1|root,33GNT@2|Bacteria,2IC2I@201174|Actinobacteria,2380S@1762|Mycobacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_322821_1 105154.Q9MBU0_9VIRU 4.45e-23 102.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_17542_1 1121440.AUMA01000012_gene1362 3.44e-61 209.0 COG5323@1|root,COG5323@2|Bacteria,1R049@1224|Proteobacteria,42UYF@68525|delta/epsilon subdivisions,2WQN3@28221|Deltaproteobacteria,2M90K@213115|Desulfovibrionales 28221|Deltaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6 k59_17542_2 156889.Mmc1_1012 9.38e-103 335.0 COG2268@1|root,COG2268@2|Bacteria,1NT13@1224|Proteobacteria,2U335@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Band 7 protein - - - - - - - - - - - - - k59_17542_4 1132836.RCCGE510_03078 7.87e-11 70.9 2E5FK@1|root,3307A@2|Bacteria,1N95D@1224|Proteobacteria,2UJ05@28211|Alphaproteobacteria,4B8UG@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_17542_7 49964.Q94MS1_9CAUD 1.05e-133 389.0 4QB4H@10239|Viruses,4QYQI@35237|dsDNA viruses no RNA stage,4QUAR@28883|Caudovirales,4QNUV@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_115490_1 1283287.KB822583_gene2825 1.77e-22 97.8 2CHG1@1|root,32YZS@2|Bacteria,2IRMN@201174|Actinobacteria,4DUQ8@85009|Propionibacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - k59_116928_1 1471542.A0A023ZWF6_9CAUD 4.67e-14 74.3 4QM6C@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_81171_1 1261131.lam_651 3.69e-31 128.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,2UNT9@28211|Alphaproteobacteria,4BJFM@82115|Rhizobiaceae 28211|Alphaproteobacteria L COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_178777_1 1121033.AUCF01000009_gene1058 1.26e-38 138.0 COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2U3H1@28211|Alphaproteobacteria,2JR8A@204441|Rhodospirillales 204441|Rhodospirillales E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit - - - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth k59_8107_1 913183.E5RV10_9CAUD 2.4e-125 386.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_275402_1 338966.Ppro_2991 1.86e-46 159.0 COG3409@1|root,COG3409@2|Bacteria,1RAFU@1224|Proteobacteria,42Z43@68525|delta/epsilon subdivisions,2WU3U@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - - k59_93979_1 742159.HMPREF0004_1809 3.31e-18 84.3 COG3740@1|root,COG3740@2|Bacteria,1NHKT@1224|Proteobacteria,2VV07@28216|Betaproteobacteria,3T8GV@506|Alcaligenaceae 28216|Betaproteobacteria S Caudovirus prohead serine protease - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78 k59_93979_4 759913.SDSE_1378 1.34e-66 226.0 COG4695@1|root,COG4695@2|Bacteria,1TP8B@1239|Firmicutes,4HBWE@91061|Bacilli 91061|Bacilli OU Phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_93979_5 1111134.HMPREF1253_0386 1.15e-14 78.6 COG4626@1|root,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,248RI@186801|Clostridia,22FYQ@1570339|Peptoniphilaceae 186801|Clostridia S large subunit - - - - - - - - - - - - Terminase_1 k59_56775_2 1538804.A0A088F6S0_9CAUD 5.52e-34 124.0 4QBY9@10239|Viruses,4QQRZ@28883|Caudovirales,4QKU6@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_275410_2 1477404.A0A023NI07_9CAUD 1.64e-74 245.0 4QF3C@10239|Viruses,4QWIA@35237|dsDNA viruses no RNA stage,4QU4U@28883|Caudovirales,4QNNQ@10744|Podoviridae 10744|Podoviridae S host cell wall - - - - - - - - - - - - - k59_166044_5 375286.mma_2192 0.000275 52.4 2ES6Y@1|root,33JRQ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_166044_6 1121438.JNJA01000039_gene1897 1.9e-05 57.0 2DNH7@1|root,32XH1@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_302312_1 1207063.P24_13825 1.16e-21 98.6 2DIIY@1|root,303ET@2|Bacteria,1RD2S@1224|Proteobacteria,2U8HK@28211|Alphaproteobacteria,2JX0C@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_46350_4 1051006.HMPREF1162_1154 5.37e-24 107.0 2F0SM@1|root,33TUQ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Rep_trans k59_217492_1 1089544.KB912942_gene4069 0.000742 44.3 COG0863@1|root,COG0863@2|Bacteria,2I9DJ@201174|Actinobacteria,4E81H@85010|Pseudonocardiales 201174|Actinobacteria L DNA methylase - - 2.1.1.113,2.1.1.72 ko:K00571,ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_240389_1 1986029.Q9MBM3_9VIRU 4.67e-36 135.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_70798_1 638302.HMPREF0908_1572 6.27e-15 81.6 COG0463@1|root,COG0463@2|Bacteria,1TSF5@1239|Firmicutes,4H2PY@909932|Negativicutes 909932|Negativicutes M Glycosyltransferase, group 2 family protein - - - - - - - - - - - - Glycos_transf_2,TPR_8 k59_95983_2 478749.BRYFOR_08514 1.61e-33 120.0 2ARVA@1|root,31H70@2|Bacteria,1V7JT@1239|Firmicutes,24JPE@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - HK97-gp10_like k59_314002_1 211586.SO_4669 2.03e-16 85.1 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,2Q9N3@267890|Shewanellaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_264685_1 102129.Lepto7375DRAFT_7369 2.02e-40 154.0 COG5323@1|root,COG5323@2|Bacteria 2|Bacteria M Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_3,Terminase_6,Terminase_6C k59_156336_1 520999.PROVALCAL_01902 2.79e-09 59.3 2EJ6P@1|root,33CXW@2|Bacteria,1NPIH@1224|Proteobacteria,1SIRF@1236|Gammaproteobacteria,3ZAE2@586|Providencia 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_9792_1 548476.cauri_1991 1.39e-05 51.6 COG1475@1|root,COG1475@2|Bacteria,2GMF3@201174|Actinobacteria,22NNE@1653|Corynebacteriaceae 201174|Actinobacteria K transcriptional regulators - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_58656_2 1556290.A0A0A0RM05_9CAUD 9.49e-144 423.0 4QAYV@10239|Viruses,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - k59_143883_1 742740.HMPREF9474_02303 7.7e-73 248.0 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia,221YV@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_72798_1 1340826.S5Y506_9CAUD 6.94e-30 118.0 4QARC@10239|Viruses,4QV4E@35237|dsDNA viruses no RNA stage,4QPDS@28883|Caudovirales,4QKXX@10699|Siphoviridae 10699|Siphoviridae S RNase_H superfamily - - - - - - - - - - - - - k59_11380_1 243924.LT42_17145 5.54e-33 127.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1RP8Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria K terminase - - - - - - - - - - - - Terminase_1 k59_242613_1 1479238.JQMZ01000001_gene129 1.88e-51 169.0 COG3926@1|root,COG3926@2|Bacteria,1MVXW@1224|Proteobacteria,2TT3H@28211|Alphaproteobacteria,43ZTM@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Glycosyl hydrolase 108 - - - - - - - - - - - - Glyco_hydro_108,PG_binding_1,PG_binding_3 k59_387982_1 4929.XP_001486882.1 2.78e-37 149.0 COG5108@1|root,KOG1038@2759|Eukaryota,38EAY@33154|Opisthokonta,3NU1C@4751|Fungi,3QN4S@4890|Ascomycota,3RS68@4891|Saccharomycetes,479W3@766764|Debaryomycetaceae 4751|Fungi KL DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates - - 2.7.7.6 ko:K10908 - - - - ko00000,ko01000,ko03029 - - - RNA_pol,RPOL_N k59_352226_1 530564.Psta_0658 3.11e-61 208.0 COG5362@1|root,COG5362@2|Bacteria,2J0FK@203682|Planctomycetes 203682|Planctomycetes S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_278920_1 862908.BMS_1457 4.42e-22 92.0 COG1694@1|root,COG1694@2|Bacteria 2|Bacteria FG Mazg nucleotide pyrophosphohydrolase MA20_27270 - - - - - - - - - - - MazG k59_22806_1 1096930.L284_17610 1.25e-09 64.7 COG1475@1|root,COG1475@2|Bacteria,1MVF9@1224|Proteobacteria,2TR0P@28211|Alphaproteobacteria,2K1WS@204457|Sphingomonadales 204457|Sphingomonadales K partitioning protein, ParB - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_266460_4 1486426.A0A023W6X2_9CAUD 5.96e-63 197.0 4QE7X@10239|Viruses,4QVF0@35237|dsDNA viruses no RNA stage,4QPUM@28883|Caudovirales 28883|Caudovirales S Cytidine and deoxycytidylate deaminase zinc-binding region - - - - - - - - - - - - - k59_206233_2 1502851.FG93_05529 4.64e-37 133.0 COG0847@1|root,COG0847@2|Bacteria,1R9YS@1224|Proteobacteria,2UWDS@28211|Alphaproteobacteria 28211|Alphaproteobacteria L 3' exoribonuclease, RNase T-like - - - - - - - - - - - - DUF5051 k59_97592_13 1437882.AZRU01000104_gene3919 2.16e-20 91.7 COG2404@1|root,COG2404@2|Bacteria,1MXEH@1224|Proteobacteria,1SADM@1236|Gammaproteobacteria,1YI8A@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S phosphoesterase DHHA1 - - - - - - - - - - - - DHHA1 k59_158466_2 1379714.S5TND6_9CIRC 1.7e-56 193.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_453_1 2003327.CAPSD_BPCHP 5.4e-33 135.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_453_6 1234888.K0A2J2_9VIRU 1.32e-46 167.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_170354_3 465515.Mlut_14360 9.93e-36 132.0 COG1652@1|root,COG1652@2|Bacteria,2GK68@201174|Actinobacteria,1W98D@1268|Micrococcaceae 201174|Actinobacteria S Transglycosylase-like domain - - - ko:K21687,ko:K21691 - - - - ko00000 - GH23 - LysM,Transglycosylas k59_170354_4 1172188.KB911820_gene2885 3.19e-268 759.0 COG0209@1|root,COG0209@2|Bacteria,2IC1H@201174|Actinobacteria 201174|Actinobacteria F Ribonucleotide reductase, barrel domain - - - - - - - - - - - - Ribonuc_red_lgC k59_170354_6 953739.SVEN_4145 1.99e-12 76.6 2BZJP@1|root,33QCI@2|Bacteria,2IFNW@201174|Actinobacteria 201174|Actinobacteria S Hyaluronidase protein (HylP) - - - - - - - - - - - - Hyaluronidase_1 k59_73348_3 1056816.JAFQ01000004_gene4203 1.12e-10 58.9 2B5X5@1|root,31YT4@2|Bacteria,2I06K@201174|Actinobacteria,4G515@85025|Nocardiaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_73348_4 1385521.N803_17340 6.94e-56 177.0 COG1487@1|root,COG1487@2|Bacteria,2IMGJ@201174|Actinobacteria 201174|Actinobacteria S Toxic component of a toxin-antitoxin (TA) module. An RNase - GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113 - - - - - - - - - - PIN k59_292038_1 1618254.A0A0C5IBG4_9CIRC 1.27e-109 324.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_49127_1 469378.Ccur_02660 9.7e-41 157.0 COG1340@1|root,COG5283@1|root,COG1340@2|Bacteria,COG5283@2|Bacteria,2I8JB@201174|Actinobacteria,4CX1V@84998|Coriobacteriia 84998|Coriobacteriia S Phage tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail k59_255491_1 1502724.FF80_03352 1.25e-120 401.0 COG4733@1|root,COG4733@2|Bacteria,1Q2WW@1224|Proteobacteria,2TUS9@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Phage-related protein, tail component - - - - - - - - - - - - DUF1983,Phage-tail_3 k59_255491_5 411684.HPDFL43_16336 3.24e-12 79.0 28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TURR@28211|Alphaproteobacteria,43JKV@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_454_1 105154.Q9MBU6_9VIRU 4.2e-71 233.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_255493_1 1042375.AFPL01000042_gene3813 1.61e-29 109.0 2AD08@1|root,312N7@2|Bacteria,1NDC4@1224|Proteobacteria,1SAPT@1236|Gammaproteobacteria,467W0@72275|Alteromonadaceae 1236|Gammaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_158493_6 1122201.AUAZ01000010_gene2520 1.23e-50 174.0 29UKS@1|root,30FY7@2|Bacteria,1RGKW@1224|Proteobacteria,1SKMS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_109792_2 1545915.JROG01000009_gene2733 6.68e-08 55.5 29B7J@1|root,2ZY5Y@2|Bacteria,1NND5@1224|Proteobacteria,2UKRN@28211|Alphaproteobacteria,2K8CI@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - k59_194942_1 1609634.A0A0C5ANA6_9VIRU 8.67e-09 61.6 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_340560_3 873533.HMPREF0663_10799 1.45e-42 147.0 COG1262@1|root,COG1262@2|Bacteria,4NEUZ@976|Bacteroidetes 976|Bacteroidetes KLT PFAM Formylglycine-generating sulfatase enzyme - - - - - - - - - - - - BNR_2,FGE-sulfatase k59_340560_5 1429767.W6AQU3_9CAUD 7.03e-06 49.3 4QAR6@10239|Viruses,4QUTK@35237|dsDNA viruses no RNA stage,4QPS2@28883|Caudovirales,4QNRU@10744|Podoviridae 10744|Podoviridae S dUTPase - - - - - - - - - - - - - k59_12505_2 1692249.A0A0K1RL40_9CIRC 2.54e-39 145.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_328583_1 1123278.KB893560_gene3097 5.53e-09 58.9 2DRJI@1|root,33C1H@2|Bacteria,4P7A3@976|Bacteroidetes,47W9Y@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - VRR_NUC k59_1060_1 497321.C664_02220 9.45e-24 99.4 COG4643@1|root,COG4643@2|Bacteria,1MW9E@1224|Proteobacteria,2VKFM@28216|Betaproteobacteria,2KVKJ@206389|Rhodocyclales 206389|Rhodocyclales S Zinc-binding domain of primase-helicase - - - ko:K06919 - - - - ko00000 - - - Prim_Zn_Ribbon,Toprim_3 k59_122622_1 1220603.L7TJH2_9CAUD 1.43e-27 115.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales 28883|Caudovirales S DNA-dependent RNA polymerase - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_171094_2 1385658.U5KPZ6_9VIRU 2.07e-29 120.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_243893_1 1157635.KB892046_gene5805 4.24e-56 202.0 COG0749@1|root,COG0749@2|Bacteria,2I975@201174|Actinobacteria 201174|Actinobacteria L COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_pol_A,DNA_pol_A_exo1 k59_49814_2 1117943.SFHH103_00136 6.73e-26 103.0 2AIT3@1|root,319A1@2|Bacteria,1Q25I@1224|Proteobacteria,2V9MC@28211|Alphaproteobacteria,4BJY9@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_292764_2 1484479.DI14_04720 0.00061 51.2 COG5280@1|root,COG5283@1|root,COG5412@1|root,COG5280@2|Bacteria,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HAFE@91061|Bacilli,3WF4W@539002|Bacillales incertae sedis 91061|Bacilli S Phage tail tape measure protein - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,SLT k59_98307_5 1219035.NT2_13_00580 3.66e-56 199.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_220070_2 398580.Dshi_1419 7.99e-26 97.8 COG3750@1|root,COG3750@2|Bacteria,1N77J@1224|Proteobacteria,2UFX6@28211|Alphaproteobacteria 28211|Alphaproteobacteria D Belongs to the UPF0335 family - - - - - - - - - - - - DUF2312 k59_231917_1 1000565.METUNv1_00538 1.18e-53 189.0 COG4653@1|root,COG4653@2|Bacteria,1MWMB@1224|Proteobacteria,2VN8K@28216|Betaproteobacteria,2KXMM@206389|Rhodocyclales 206389|Rhodocyclales S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_159172_2 1379725.S5TMY9_9CIRC 6.92e-37 141.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_37520_1 293826.Amet_4047 0.000103 48.9 2BX5K@1|root,32R8G@2|Bacteria,1V9DD@1239|Firmicutes,24K3D@186801|Clostridia,36M5C@31979|Clostridiaceae 186801|Clostridia L HNH endonuclease - - - - - - - - - - - - HNH_3 k59_37520_2 298653.Franean1_2043 4.66e-30 124.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4ES9K@85013|Frankiales 201174|Actinobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_280990_1 1136534.J9PUM4_9CAUD 4.48e-66 216.0 4QY3P@35237|dsDNA viruses no RNA stage,4QQ7H@28883|Caudovirales,4QK0H@10662|Myoviridae 10662|Myoviridae S Terminase-like family - - - - - - - - - - - - - k59_365403_1 49964.Q94MR7_9CAUD 4.79e-63 214.0 4QERB@10239|Viruses,4R014@35237|dsDNA viruses no RNA stage,4QTGJ@28883|Caudovirales,4QNZG@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_13563_6 1385658.U5KPZ6_9VIRU 3.86e-206 590.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_282251_4 585.DR95_28 2.54e-49 159.0 2E1C1@1|root,32WRT@2|Bacteria 2|Bacteria S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Peptidase_M15_4 k59_282251_5 690850.Desaf_0681 1.32e-27 106.0 2AD08@1|root,312N7@2|Bacteria,1NDC4@1224|Proteobacteria,42VQI@68525|delta/epsilon subdivisions,2WS8T@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Holin of 3TMs, for gene-transfer release - - - - - - - - - - - - GTA_holin_3TM k59_282251_6 1429916.X566_20010 4.71e-26 103.0 COG1917@1|root,COG1917@2|Bacteria,1N6Q0@1224|Proteobacteria,2UKI2@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - - k59_282251_8 329254.Q2NPF7_9CAUD 1.07e-37 134.0 4QB0U@10239|Viruses,4QZQJ@35237|dsDNA viruses no RNA stage,4QR5X@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_282251_10 1122604.JONR01000060_gene2302 2.28e-11 68.2 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RQUR@1236|Gammaproteobacteria,1X2Z8@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen - - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC k59_135612_1 938709.AUSH02000051_gene230 3.01e-05 52.0 COG4733@1|root,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - - - - - - - - - - - - k59_63134_1 1165094.RINTHH_3920 3.14e-11 66.6 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_63134_3 2003327.CAPSD_BPCHP 3.43e-115 360.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_63134_9 1385658.U5KNR1_9VIRU 3.1e-39 141.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_232894_1 582899.Hden_0156 4.76e-24 105.0 COG3170@1|root,COG3170@2|Bacteria,1N4R0@1224|Proteobacteria,2UCUV@28211|Alphaproteobacteria 28211|Alphaproteobacteria NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - k59_318313_1 1461693.ATO10_06466 8.52e-12 68.9 COG1086@1|root,COG1086@2|Bacteria,1N0T2@1224|Proteobacteria,2UIA1@28211|Alphaproteobacteria 28211|Alphaproteobacteria GM Methyltransferase domain - - - - - - - - - - - - Methyltransf_24 k59_318313_2 1122226.AUHX01000009_gene2854 1.19e-21 94.7 2DM5Y@1|root,31UPK@2|Bacteria,4P38I@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - k59_366501_1 1556290.A0A0A0RL96_9CAUD 2.13e-67 224.0 4QGMJ@10239|Viruses,4QSYG@28883|Caudovirales,4QM5B@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_99396_1 979533.F1D0U2_9CAUD 4.43e-07 53.9 4QAIV@10239|Viruses,4QYFZ@35237|dsDNA viruses no RNA stage,4QQUY@28883|Caudovirales,4QNQK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_306107_2 1429046.RR21198_3112 1.72e-14 77.0 2BJAQ@1|root,32DKM@2|Bacteria,2H7Z3@201174|Actinobacteria,4G4A8@85025|Nocardiaceae 201174|Actinobacteria S NUMOD4 motif - - - - - - - - - - - - HNH_3,NUMOD4 k59_111538_3 105154.Q9MBU6_9VIRU 1.54e-216 617.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_111538_5 1165094.RINTHH_3920 4.48e-81 254.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_283695_1 1000565.METUNv1_03730 1.7e-05 47.8 2DSGW@1|root,33G2M@2|Bacteria,1NKRQ@1224|Proteobacteria,2VYBE@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF2523) - - - - - - - - - - - - DUF2523 k59_283695_2 1411685.U062_00586 9.47e-15 74.7 COG0433@1|root,COG0433@2|Bacteria,1QTVP@1224|Proteobacteria,1T1IQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_161328_1 1379695.S5TNA9_9CIRC 2.53e-21 100.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_173376_1 1385658.U5KPZ6_9VIRU 6.5e-53 184.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_39333_1 1122165.AUHS01000014_gene2657 2.57e-16 84.0 COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,1JCFU@118969|Legionellales 118969|Legionellales L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS k59_27511_2 925775.XVE_4782 5.11e-67 216.0 COG4128@1|root,COG4128@2|Bacteria,1R51Y@1224|Proteobacteria,1T2BV@1236|Gammaproteobacteria,1X750@135614|Xanthomonadales 135614|Xanthomonadales S Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_355568_1 399739.Pmen_3960 5.25e-17 89.4 2EBVZ@1|root,335VC@2|Bacteria,1RHVC@1224|Proteobacteria,1SND1@1236|Gammaproteobacteria,1YD8D@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_295029_1 145579.CAPSD_BPPHM 8.62e-26 113.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_295029_5 1986029.Q9MBM3_9VIRU 4.27e-21 99.4 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_100676_1 649831.L083_7782 6.11e-06 56.6 COG2304@1|root,COG4719@1|root,COG2304@2|Bacteria,COG4719@2|Bacteria 2|Bacteria IU oxidoreductase activity - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - CHU_C,DUF11,He_PIG,SdrD_B,VWA,VWA_2 k59_88495_2 1385658.U5KPZ6_9VIRU 3.56e-219 623.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_88495_3 105154.Q9MBU3_9VIRU 1.45e-11 68.2 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_88495_4 1986029.Q9MBM6_9VIRU 9.48e-26 102.0 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_88495_6 1165094.RINTHH_3920 5.31e-82 258.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_76193_2 323098.Nwi_1554 9.99e-10 65.5 COG4725@1|root,COG4725@2|Bacteria,1R553@1224|Proteobacteria,2TRP6@28211|Alphaproteobacteria,3JXMZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria KT Belongs to the MT-A70-like family - - - - - - - - - - - - MT-A70,ParBc k59_174926_1 1313421.JHBV01000016_gene5476 3.96e-33 130.0 2CDGZ@1|root,34CGM@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_185318_3 1094508.Tsac_0966 5.91e-08 60.8 COG0209@1|root,COG1372@1|root,COG0209@2|Bacteria,COG1372@2|Bacteria,1TPFH@1239|Firmicutes,249EN@186801|Clostridia,42F6G@68295|Thermoanaerobacterales 186801|Clostridia F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdJ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Intein_splicing,LAGLIDADG_3,Ribonuc_red_2_N,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD k59_101897_1 378806.STAUR_5231 4.64e-23 97.8 COG0582@1|root,COG0582@2|Bacteria 2|Bacteria L DNA integration - - - ko:K14059 - - - - ko00000 - - - Arm-DNA-bind_2,Phage_int_SAM_2,Phage_integrase k59_40712_2 309801.trd_A0646 1.05e-30 120.0 COG0739@1|root,COG0741@1|root,COG0739@2|Bacteria,COG0741@2|Bacteria,2G6NM@200795|Chloroflexi,27XW3@189775|Thermomicrobia 189775|Thermomicrobia M Lytic transglycosylase catalytic - - - - - - - - - - - - Peptidase_M23,SLT k59_320877_1 1519439.JPJG01000011_gene55 3.27e-05 49.3 COG1783@1|root,COG1783@2|Bacteria,1TUW4@1239|Firmicutes,25MM2@186801|Clostridia,2N8F3@216572|Oscillospiraceae 186801|Clostridia S phage Terminase large subunit - - - - - - - - - - - - - k59_174934_1 1126411.I1TEL3_9CIRC 4.66e-31 124.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_211712_1 1692250.A0A0K1RLR1_9CIRC 1.5e-128 374.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_77432_4 1472912.A0A023NG96_9CAUD 6.43e-26 97.4 4QDWQ@10239|Viruses,4QV9H@35237|dsDNA viruses no RNA stage,4QT88@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_247432_6 1449351.RISW2_23880 2.03e-34 124.0 COG3023@1|root,COG3023@2|Bacteria,1N032@1224|Proteobacteria,2U2D2@28211|Alphaproteobacteria,4KN9J@93682|Roseivivax 28211|Alphaproteobacteria V N-acetylmuramoyl-L-alanine amidase - - 3.5.1.28 ko:K01447 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Amidase_2,PG_binding_1 k59_332882_2 794903.OPIT5_06130 1.08e-68 218.0 COG0270@1|root,COG0270@2|Bacteria 2|Bacteria L DNA (cytosine-5-)-methyltransferase activity ydiP - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_89823_2 1197951.I6R9K8_9CAUD 7.61e-129 377.0 4QFIC@10239|Viruses,4QXG2@35237|dsDNA viruses no RNA stage,4QTVA@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_332915_6 694427.Palpr_1970 1.18e-31 133.0 COG4675@1|root,COG4675@2|Bacteria 2|Bacteria M tail collar domain protein - - - - - - - - - - - - Collar k59_78831_1 1357423.S5MAX6_9CAUD 1.49e-19 92.8 4QCR0@10239|Viruses,4QVAV@35237|dsDNA viruses no RNA stage,4QPFK@28883|Caudovirales,4QI4N@10662|Myoviridae 10662|Myoviridae S cell wall macromolecule catabolic process - GO:0003674,GO:0003796,GO:0003824,GO:0004553,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0009405,GO:0009987,GO:0016043,GO:0016787,GO:0016798,GO:0019012,GO:0022607,GO:0033922,GO:0042802,GO:0043933,GO:0044085,GO:0044403,GO:0044409,GO:0044411,GO:0044419,GO:0044423,GO:0051259,GO:0051260,GO:0051701,GO:0051704,GO:0051828,GO:0051830,GO:0061783,GO:0065003,GO:0070206,GO:0070207,GO:0071840,GO:0085027,GO:0098015,GO:0098025 - - - - - - - - - - - k59_151782_2 1229780.BN381_100142 4.86e-33 120.0 COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,3UWQD@52018|unclassified Actinobacteria (class) 201174|Actinobacteria L Single-strand binding protein family ssb GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071944,GO:0097159,GO:1901363 - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_151782_4 1120983.KB894577_gene3655 6.97e-68 230.0 COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,1JNNI@119043|Rhodobiaceae 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_260599_1 1385658.U5KPZ6_9VIRU 5.34e-95 299.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_6068_5 1537917.JU82_03700 2.34e-58 196.0 COG0553@1|root,COG0553@2|Bacteria 2|Bacteria L helicase activity - - - - - - - - - - - - Helicase_C,PLDc_2,ResIII,SNF2_N k59_358014_2 1609634.A0A0C5ANA6_9VIRU 3.84e-16 82.4 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_78836_1 1385658.U5KPZ6_9VIRU 1.54e-94 296.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_346144_1 1618247.A0A0C5I2K0_9CIRC 2.23e-33 130.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_334263_2 1117943.SFHH103_01662 4.46e-08 58.9 COG3740@1|root,COG3740@2|Bacteria,1N2D8@1224|Proteobacteria,2UD3U@28211|Alphaproteobacteria,4B8W0@82115|Rhizobiaceae 28211|Alphaproteobacteria S Phage head maturation protease - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78 k59_334263_5 107636.JQNK01000002_gene125 6.05e-25 114.0 COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,2TRFR@28211|Alphaproteobacteria,37042@31993|Methylocystaceae 28211|Alphaproteobacteria S Phage portal protein - - - - - - - - - - - - Phage_portal k59_334263_15 443152.MDG893_20559 1.27e-99 313.0 COG2911@1|root,COG2911@2|Bacteria,1QU6S@1224|Proteobacteria,1S7WY@1236|Gammaproteobacteria 1236|Gammaproteobacteria D tail tape measure protein - - - - - - - - - - - - SLT,Tape_meas_lam_C k59_67019_1 1562701.BBOF01000081_gene253 1.45e-67 219.0 28NGF@1|root,2Z9HT@2|Bacteria,1R9QF@1224|Proteobacteria,2VPSU@28216|Betaproteobacteria,1KD23@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_91574_2 105425.BBPL01000039_gene2970 1.19e-14 75.5 COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,2GKXQ@201174|Actinobacteria,2NEZI@228398|Streptacidiphilus 201174|Actinobacteria L DnaB-like helicase N terminal domain dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3 k59_226398_1 1127515.H9C0H6_9CAUD 7.94e-06 53.9 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QI9F@10662|Myoviridae 10662|Myoviridae S Type III restriction enzyme, res subunit - - - - - - - - - - - - - k59_371236_1 105154.Q9MBU6_9VIRU 1.17e-77 249.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_201731_2 1218075.BAYA01000007_gene2722 3.71e-57 181.0 2C5J1@1|root,3067M@2|Bacteria,1N4SF@1224|Proteobacteria,2VWDM@28216|Betaproteobacteria,1K9HT@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_226640_1 1609634.A0A0C5AFV4_9VIRU 1.92e-12 67.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_335665_1 3067.XP_002947320.1 1.67e-27 122.0 COG0553@1|root,KOG1000@2759|Eukaryota,37JEZ@33090|Viridiplantae,34K36@3041|Chlorophyta 3041|Chlorophyta A SNF2 family N-terminal domain - - 3.6.4.12 ko:K14440 - - - - ko00000,ko01000,ko03036 - - - Helicase_C,SNF2_N k59_55849_1 313596.RB2501_01425 4.24e-102 322.0 COG5545@1|root,COG5545@2|Bacteria,4PMA3@976|Bacteroidetes,1IJP7@117743|Flavobacteriia 976|Bacteroidetes L VirE N-terminal domain - - - - - - - - - - - - DUF3987,PriCT_2,VirE,VirE_N k59_274592_1 589865.DaAHT2_1096 5.75e-06 50.1 COG0457@1|root,COG0457@2|Bacteria,1Q0TI@1224|Proteobacteria,431FZ@68525|delta/epsilon subdivisions,2WX2R@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_2 k59_335669_1 1392489.JPOL01000002_gene2700 6.59e-36 135.0 COG0381@1|root,COG0381@2|Bacteria,4NFTG@976|Bacteroidetes,1HZTF@117743|Flavobacteriia,2XJF6@283735|Leeuwenhoekiella 976|Bacteroidetes M UDP-N-acetylglucosamine 2-epimerase neuC - 3.2.1.183,3.2.1.184 ko:K08068,ko:K18429 ko00520,map00520 - R10187 RC00005,RC00288 ko00000,ko00001,ko01000 - - - Epimerase_2 k59_153437_1 742740.HMPREF9474_04679 5.83e-19 92.0 COG0338@1|root,COG0338@2|Bacteria,1UBIY@1239|Firmicutes,24D2Y@186801|Clostridia,223ZF@1506553|Lachnoclostridium 186801|Clostridia L D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_153437_2 1338011.BD94_1032 3.3e-31 129.0 COG0338@1|root,COG3392@1|root,COG0338@2|Bacteria,COG3392@2|Bacteria,4NFZ2@976|Bacteroidetes,1I484@117743|Flavobacteriia 976|Bacteroidetes L DNA adenine methylase dam - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_7396_2 159087.Daro_2694 1.39e-21 93.6 COG4643@1|root,COG4643@2|Bacteria,1MW9E@1224|Proteobacteria,2VKFM@28216|Betaproteobacteria,2KVKJ@206389|Rhodocyclales 206389|Rhodocyclales S Zinc-binding domain of primase-helicase - - - ko:K06919 - - - - ko00000 - - - Prim_Zn_Ribbon,Toprim_3 k59_383431_1 1132836.RCCGE510_03078 6.65e-07 57.8 2E5FK@1|root,3307A@2|Bacteria,1N95D@1224|Proteobacteria,2UJ05@28211|Alphaproteobacteria,4B8UG@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_383431_2 216596.RL3934 1.24e-88 275.0 28NGF@1|root,2ZBII@2|Bacteria,1R9KY@1224|Proteobacteria,2U1P7@28211|Alphaproteobacteria,4B747@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_226648_1 633148.Tagg_0328 2.72e-22 105.0 COG1204@1|root,arCOG00553@2157|Archaea,2XPUH@28889|Crenarchaeota 28889|Crenarchaeota L DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks hel308 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - ko:K03726 - - - - ko00000,ko01000 - - - DEAD,HHH_5,Helicase_C k59_165310_3 1123227.KB899334_gene1657 1.6e-81 254.0 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,2TV42@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Terminase large subunit - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_250254_1 1140002.I570_04012 1.28e-22 99.0 COG4653@1|root,COG4653@2|Bacteria,1V0XG@1239|Firmicutes,4HN8Z@91061|Bacilli,4B49Q@81852|Enterococcaceae 91061|Bacilli S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_7399_2 399741.Spro_4945 1.13e-27 104.0 2E3AH@1|root,32YA0@2|Bacteria,1NBUZ@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF1064) - - - - - - - - - - - - DUF1064 k59_43638_1 314230.DSM3645_23406 2.72e-05 44.3 COG1551@1|root,COG1551@2|Bacteria,2J1GQ@203682|Planctomycetes 203682|Planctomycetes T Carbon storage regulator - - - ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 - - - ko00000,ko00001,ko03019 - - - CsrA k59_165311_2 1003200.AXXA_27990 3.3e-59 194.0 28HXV@1|root,2Z83C@2|Bacteria,1PJBP@1224|Proteobacteria,2W8RH@28216|Betaproteobacteria,3T5DR@506|Alcaligenaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_349363_2 485913.Krac_12128 7.86e-20 91.3 COG0305@1|root,COG0305@2|Bacteria,2G64D@200795|Chloroflexi 200795|Chloroflexi L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_228163_2 1618238.A0A0C5IB41_9CIRC 1.86e-22 103.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_239430_2 375286.mma_2211 7.32e-34 121.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2W3M1@28216|Betaproteobacteria,475QA@75682|Oxalobacteraceae 28216|Betaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_251758_1 1172185.KB911526_gene770 1.75e-13 76.3 COG5323@1|root,COG5410@1|root,COG5323@2|Bacteria,COG5410@2|Bacteria,2IEA1@201174|Actinobacteria 201174|Actinobacteria S TIGRFAM Phage - - - - - - - - - - - - Terminase_6,Terminase_6C k59_45229_1 1500386.A0A060AFL1_9CAUD 8.92e-18 82.8 4QAIU@10239|Viruses,4QPDE@28883|Caudovirales,4QKM7@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k59_263572_1 1692257.A0A0K1RL39_9CIRC 3.27e-40 146.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_312689_2 156889.Mmc1_2604 1.75e-81 259.0 COG1475@1|root,COG4725@1|root,COG1475@2|Bacteria,COG4725@2|Bacteria,1R553@1224|Proteobacteria,2TRP6@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT Belongs to the MT-A70-like family - - - - - - - - - - - - MT-A70 k59_312689_3 34007.IT40_02330 6.22e-20 86.3 28PMA@1|root,2ZCAD@2|Bacteria,1RARQ@1224|Proteobacteria,2U6X3@28211|Alphaproteobacteria,2PUUP@265|Paracoccus 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_251760_2 1236504.HMPREF2132_06035 1.27e-14 77.0 COG1864@1|root,COG1864@2|Bacteria,4NFYJ@976|Bacteroidetes,2FNBK@200643|Bacteroidia 976|Bacteroidetes F DNA RNA non-specific endonuclease - - - ko:K01173 ko04210,map04210 - - - ko00000,ko00001,ko03029 - - - Endonuclease_NS k59_179567_1 1692252.A0A0K1RL35_9CIRC 1.96e-62 206.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_94800_1 521000.PROVRETT_05530 1.89e-21 89.0 COG3179@1|root,COG3179@2|Bacteria,1RE8K@1224|Proteobacteria,1S4U8@1236|Gammaproteobacteria,3Z9BP@586|Providencia 1236|Gammaproteobacteria S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Peptidase_M15_4 k59_117789_2 1692242.A0A0K1RKZ2_9CIRC 3.91e-22 97.8 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_312840_3 172088.AUGA01000033_gene4632 3.37e-24 102.0 28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria,2U265@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_276242_1 1230341.MJ3_13664 1.44e-14 84.7 COG0739@1|root,COG5280@1|root,COG5412@1|root,COG0739@2|Bacteria,COG5280@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HAFE@91061|Bacilli 91061|Bacilli M Phage tail tape measure protein - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,SLT k59_188323_1 1123257.AUFV01000013_gene2785 1.33e-31 123.0 COG0863@1|root,COG0863@2|Bacteria,1PCSE@1224|Proteobacteria,1SARI@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_290314_1 1692253.A0A0K1RLM4_9CIRC 1.72e-30 125.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_314525_1 1502851.FG93_01932 1.5e-15 86.3 2DPZ1@1|root,3340X@2|Bacteria,1R2EE@1224|Proteobacteria,2TZIB@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_362214_1 287.DR97_5374 9.49e-32 127.0 COG3723@1|root,COG3723@2|Bacteria,1R6DB@1224|Proteobacteria,1RZZ3@1236|Gammaproteobacteria,1YKA6@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria L RecT family recT GO:0000724,GO:0000725,GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0018130,GO:0019438,GO:0032392,GO:0032508,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043150,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_253713_2 634176.NT05HA_0469 6.93e-30 115.0 28MEG@1|root,2ZAS3@2|Bacteria,1QJWH@1224|Proteobacteria,1RY3Q@1236|Gammaproteobacteria,1Y859@135625|Pasteurellales 135625|Pasteurellales L YqaJ-like viral recombinase domain - - - - - - - - - - - - YqaJ k59_265338_1 575540.Isop_2443 4.85e-143 430.0 COG1061@1|root,COG1061@2|Bacteria,2J0ES@203682|Planctomycetes 203682|Planctomycetes L COGs COG1061 DNA or RNA helicase of superfamily II - - - ko:K19789 - - - - ko00000,ko03400 - - - Helicase_C,ResIII k59_362398_1 1121895.Q765_20725 1.69e-11 70.5 COG2374@1|root,COG3693@1|root,COG2374@2|Bacteria,COG3693@2|Bacteria 2|Bacteria G endo-1,4-beta-xylanase activity cda1 - 3.2.1.8 ko:K01181,ko:K07004 - - - - ko00000,ko01000 - - - CBM_2,CBM_4_9,CBM_5_12_2,CBM_6,Esterase,Glyco_hydro_10,Glyco_hydro_11,Polysacc_deac_1 k59_218502_1 575594.ACOH01000006_gene307 0.000253 44.3 COG1476@1|root,COG1476@2|Bacteria,1U63F@1239|Firmicutes,4IFSU@91061|Bacilli,3F6Y5@33958|Lactobacillaceae 91061|Bacilli K TRANSCRIPTIONal - - - - - - - - - - - - HTH_3 k59_218502_2 1562701.BBOF01000007_gene77 2.11e-07 53.1 COG3561@1|root,COG3645@1|root,COG3561@2|Bacteria,COG3645@2|Bacteria,1N1AT@1224|Proteobacteria,2VT1V@28216|Betaproteobacteria,1KECR@119060|Burkholderiaceae 28216|Betaproteobacteria K AntA/AntB antirepressor - - - ko:K07741 - - - - ko00000 - - - ANT,AntA k59_303129_1 795797.C497_05662 5.67e-13 74.3 COG5283@1|root,arCOG11109@2157|Archaea,2Y67M@28890|Euryarchaeota,23YYB@183963|Halobacteria 183963|Halobacteria S Phage tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail k59_327316_1 478749.BRYFOR_08521 1.8e-37 147.0 28JK5@1|root,2Z9D1@2|Bacteria,1UJZJ@1239|Firmicutes,24D64@186801|Clostridia 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - Peptidase_S78 k59_327316_2 428125.CLOLEP_01413 1.75e-36 126.0 2E2Y0@1|root,32XYV@2|Bacteria,1VD9S@1239|Firmicutes,24PK0@186801|Clostridia,3WPDR@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_327316_4 411460.RUMTOR_01342 4.17e-94 281.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_374938_1 488538.SAR116_0393 1.09e-37 145.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT52@1224|Proteobacteria,2TVNI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_2 k59_132845_1 156889.Mmc1_1722 7.8e-16 85.9 COG4675@1|root,COG4675@2|Bacteria,1Q34D@1224|Proteobacteria,2UJKF@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Membrane - - - - - - - - - - - - - k59_47289_1 1280944.HY17_04705 0.000101 50.8 2E8SI@1|root,3333B@2|Bacteria,1N7MG@1224|Proteobacteria,2UJSF@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_71743_2 1385658.U5KQQ9_9VIRU 0.000359 48.9 4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_388426_1 1692262.A0A0K1RL89_9CIRC 1.69e-32 123.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388426_2 1692257.A0A0K1RL39_9CIRC 2.91e-21 92.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388432_1 1692258.A0A0K1RL51_9CIRC 3.99e-17 87.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388434_2 145579.CAPSD_BPPHM 1.75e-95 307.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_191970_1 314607.KB13_1178 8.52e-27 109.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2VIKN@28216|Betaproteobacteria,1KPR6@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_191970_2 1235457.C404_25690 1.2e-39 152.0 COG0210@1|root,COG0210@2|Bacteria,1R4PV@1224|Proteobacteria,2VPRB@28216|Betaproteobacteria,1K216@119060|Burkholderiaceae 28216|Betaproteobacteria L UvrD-like helicase C-terminal domain - - - - - - - - - - - - AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2 k59_388437_1 105154.Q9MBU0_9VIRU 1.1e-28 119.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_388437_3 1385658.U5KPZ6_9VIRU 3.13e-177 518.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_388437_4 1609634.A0A0C5ANA6_9VIRU 1.36e-06 54.7 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_388684_1 1692249.A0A0K1RLN8_9CIRC 4.33e-18 83.2 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_170294_2 1033991.RLEG12_18560 1.39e-76 258.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria,4BCQ8@82115|Rhizobiaceae 28211|Alphaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_170294_10 388051.AUFE01000035_gene4020 4.14e-86 276.0 COG4653@1|root,COG4653@2|Bacteria 2|Bacteria G Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_170294_13 172088.AUGA01000071_gene7569 1.78e-47 181.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_170294_17 1472912.A0A023NGU4_9CAUD 9.65e-25 112.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019058,GO:0019062,GO:0022610,GO:0039638,GO:0044403,GO:0044406,GO:0044419,GO:0044423,GO:0044650,GO:0051704,GO:0098015,GO:0098024 - - - - - - - - - - - k59_279962_2 691965.D4P7I0_9CAUD 2.7e-46 162.0 4QDSZ@10239|Viruses,4QXJ8@35237|dsDNA viruses no RNA stage,4QPKE@28883|Caudovirales,4QM8R@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_85468_1 1692244.A0A0K1RLR5_9CIRC 8.04e-86 267.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_133967_1 1121456.ATVA01000014_gene690 2.96e-39 145.0 28HS3@1|root,2Z7ZE@2|Bacteria,1QH9A@1224|Proteobacteria,435JV@68525|delta/epsilon subdivisions,2WZY3@28221|Deltaproteobacteria,2M8GN@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_352814_1 1283079.M1HMB6_9CAUD 2.41e-28 112.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNI0@10744|Podoviridae 10744|Podoviridae S viral capsid - GO:0003674,GO:0005488,GO:0005515,GO:0042802 - - - - - - - - - - - k59_194831_1 759938.F5BSB4_9CIRC 2.29e-35 135.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_291972_1 742740.HMPREF9474_02303 4.58e-85 286.0 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia,221YV@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_206996_3 145579.CAPSD_BPPHM 1.19e-24 107.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_328480_3 1249997.JHZW01000003_gene3734 3.45e-09 68.2 COG1511@1|root,COG3210@1|root,COG1511@2|Bacteria,COG3210@2|Bacteria,4PKI0@976|Bacteroidetes,1IKUE@117743|Flavobacteriia,2PI31@252356|Maribacter 976|Bacteroidetes U PFAM Collagen triple helix repeat (20 copies) - - - - - - - - - - - - - k59_418_2 520999.PROVALCAL_02561 1.51e-16 82.4 2DBAD@1|root,2Z82M@2|Bacteria,1QWBK@1224|Proteobacteria,1T363@1236|Gammaproteobacteria,3Z9UV@586|Providencia 1236|Gammaproteobacteria S Bacteriophage replication protein O - - - - - - - - - - - - Phage_rep_O k59_122284_5 2003327.CAPSD_BPCHP 2.12e-44 172.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_25042_1 1385658.U5KPZ6_9VIRU 3.48e-32 125.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_49455_2 1609634.A0A0C5AFT2_9VIRU 7.08e-66 217.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_49455_4 105154.Q9MBU6_9VIRU 1e-202 582.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_49455_5 105154.Q9MBU3_9VIRU 3.2e-12 70.9 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_49455_6 1986029.Q9MBM6_9VIRU 4.58e-13 70.1 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_85815_1 2754.EH55_08555 2.62e-23 109.0 COG4643@1|root,COG5545@1|root,COG4643@2|Bacteria,COG5545@2|Bacteria 2|Bacteria P DNA integration - - - ko:K06919 - - - - ko00000 - - - PriCT_2,Toprim_3,Toprim_4,VirE,VirE_N k59_207478_1 1234888.K0A2J2_9VIRU 1.96e-63 212.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_122360_1 1609634.A0A0C5AFV4_9VIRU 9.87e-146 430.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_122360_2 1609634.A0A0C5ANA6_9VIRU 6.38e-21 92.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_316716_2 204669.Acid345_3158 2.02e-23 99.4 28NSJ@1|root,2ZBRH@2|Bacteria,3Y8AG@57723|Acidobacteria,2JNAQ@204432|Acidobacteriia 204432|Acidobacteriia - - - - - - - - - - - - - - - k59_316716_4 278957.ABEA03000120_gene1182 1.36e-12 74.7 COG4733@1|root,COG4733@2|Bacteria,46YHY@74201|Verrucomicrobia,3K9MG@414999|Opitutae 414999|Opitutae S cellulase activity - - - - - - - - - - - - - k59_146685_2 28369.VG55_BPMD2 5.82e-07 54.3 4QAV0@10239|Viruses,4QY41@35237|dsDNA viruses no RNA stage,4QSR9@28883|Caudovirales,4QKWJ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_146685_3 500637.PROVRUST_04522 3.87e-13 72.4 COG1896@1|root,COG1896@2|Bacteria,1PP1F@1224|Proteobacteria,1TC5Y@1236|Gammaproteobacteria,3ZAD7@586|Providencia 1236|Gammaproteobacteria S Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates - - - - - - - - - - - - - k59_146685_4 68199.JNZO01000002_gene1222 2.19e-08 55.1 2CC1Y@1|root,32RUK@2|Bacteria,2IQ4Q@201174|Actinobacteria 201174|Actinobacteria K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA whmD - - ko:K18955 - - - - ko00000,ko03000 - - - Whib k59_146685_5 883066.HMPREF9233_01230 1.62e-11 63.2 2CC1Y@1|root,32RUK@2|Bacteria,2IQ4Q@201174|Actinobacteria,4D6CU@85005|Actinomycetales 201174|Actinobacteria K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA whiB - - ko:K18955 - - - - ko00000,ko03000 - - - Whib k59_98937_1 105154.Q9MBU6_9VIRU 7.58e-49 174.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_74755_2 645099.MREP_BBTVA 3.25e-10 63.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_208605_1 105154.Q9MBU6_9VIRU 6.49e-117 353.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_123452_1 1220601.L7TJ79_9CAUD 6.58e-87 278.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales 28883|Caudovirales S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_378337_2 1454004.AW11_03825 0.000924 44.3 2E5FX@1|root,3307M@2|Bacteria,1N8E5@1224|Proteobacteria,2VWUI@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_378337_5 220341.16506051 9.56e-49 178.0 COG1783@1|root,COG1783@2|Bacteria,1MWGP@1224|Proteobacteria,1S8D6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_232564_2 1788445.A0A190WHA3_9CIRC 2.05e-19 87.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_147543_1 1145276.T479_03280 1.66e-16 81.6 COG1861@1|root,COG1861@2|Bacteria,1U4YD@1239|Firmicutes,4HG5W@91061|Bacilli,3J061@400634|Lysinibacillus 91061|Bacilli M Cytidylyltransferase - - - ko:K07257 - - - - ko00000 - - - CTP_transf_3 k59_341874_2 1114964.L485_16405 1.19e-20 93.6 29CV4@1|root,2ZZT9@2|Bacteria,1Q8BG@1224|Proteobacteria,2UVSE@28211|Alphaproteobacteria,2KB9F@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - k59_171981_1 195250.CM001776_gene447 8.41e-17 82.4 COG2003@1|root,COG2003@2|Bacteria,1G2BJ@1117|Cyanobacteria,1GYIT@1129|Synechococcus 1117|Cyanobacteria E Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - HHH,RadC k59_378487_2 1123237.Salmuc_02477 2.67e-07 54.3 2DTN7@1|root,33M1C@2|Bacteria,1NHG1@1224|Proteobacteria,2UK42@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_38211_1 1609634.A0A0C5ANA6_9VIRU 1.05e-16 81.3 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_87885_1 115417.EPrPW00000018592 2.84e-07 62.0 COG0553@1|root,KOG0390@2759|Eukaryota,1MCX7@121069|Pythiales 121069|Pythiales L DNA repair and recombination protein RAD54. Source PGD - - - - - - - - - - - - Helicase_C,SNF2_N k59_197255_2 399742.Ent638_1051 3.43e-08 57.8 29XAK@1|root,30J05@2|Bacteria,1PFT8@1224|Proteobacteria,1TAKQ@1236|Gammaproteobacteria,3X45C@547|Enterobacter 399742.Ent638_1051|- - - - - - - - - - - - - - - - k59_148377_9 1380394.JADL01000008_gene3768 3.5e-92 309.0 COG3064@1|root,COG3064@2|Bacteria,1R6JV@1224|Proteobacteria,2U5NE@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Membrane - - - - - - - - - - - - - k59_319053_2 348824.LPU83_1517 4.09e-15 77.0 2AJ3J@1|root,319MZ@2|Bacteria,1Q7B3@1224|Proteobacteria,2VDFQ@28211|Alphaproteobacteria,4BHE6@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - Phage_connect_1 k59_14215_11 742733.HMPREF9469_05020 2.3e-52 187.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,221IX@1506553|Lachnoclostridium 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_197372_1 1176422.I6S6X7_9CAUD 3.57e-18 89.4 4QEB6@10239|Viruses,4QZWZ@35237|dsDNA viruses no RNA stage,4QQYS@28883|Caudovirales,4QMUW@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_355326_1 1380394.JADL01000006_gene5249 3.12e-21 105.0 28QU5@1|root,2ZD9H@2|Bacteria,1RAU8@1224|Proteobacteria,2VC6Q@28211|Alphaproteobacteria,2JY0A@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_342980_1 665956.HMPREF1032_02256 2.3e-16 84.3 COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia,3WH3F@541000|Ruminococcaceae 186801|Clostridia E Phage tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail k59_14219_1 269797.Mbar_A3575 2.08e-10 67.4 COG3291@1|root,arCOG02515@1|root,arCOG02527@1|root,arCOG02510@2157|Archaea,arCOG02515@2157|Archaea,arCOG02527@2157|Archaea 2157|Archaea O PFAM PKD domain containing protein - - - - - - - - - - - - CARDB,CBM_6,CHB_HEX_C_1,DUF3344,NosD,PKD k59_222033_4 1319815.HMPREF0202_02631 7.98e-37 157.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,378G8@32066|Fusobacteria 32066|Fusobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,HHH_5 k59_88037_1 1379713.S5SYD9_9CIRC 1.73e-13 75.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_209931_1 1406780.U5PZU8_9CAUD 5.69e-31 127.0 4QBMV@10239|Viruses,4QUU6@35237|dsDNA viruses no RNA stage,4QQ7Y@28883|Caudovirales,4QNK5@10744|Podoviridae 10744|Podoviridae S DNA-directed RNA polymerase activity - GO:0008150,GO:0016032,GO:0019080,GO:0019083,GO:0039695,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_209931_5 1123508.JH636442_gene4425 3.06e-48 158.0 2CCFB@1|root,32RVJ@2|Bacteria 2|Bacteria S zinc-finger-containing domain - - - - - - - - - - - - DUF3268 k59_344219_1 1379717.S5SY19_9CIRC 1.78e-47 168.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_40199_1 44088.Q6VZJ4_CNPV 8.59e-29 119.0 4QB1C@10239|Viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_101427_3 984262.SGRA_2270 3.21e-21 97.8 COG3409@1|root,COG3409@2|Bacteria 2|Bacteria M Peptidoglycan-binding domain 1 protein MA20_21840 - 3.2.1.96,3.5.1.28 ko:K01227,ko:K01448,ko:K03791,ko:K13277,ko:K17733 ko00511,ko01503,ko02024,map00511,map01503,map02024 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036,ko03110 - GH19 - Amidase_3,DUF1036,Glucosaminidase,PG_binding_1,SH3_3 k59_332386_1 1609634.A0A0C5AFV4_9VIRU 9.57e-103 319.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_15311_1 1304275.C41B8_05408 9.15e-39 142.0 2DVPY@1|root,33WQ8@2|Bacteria,1N9VQ@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_149839_2 1120971.AUCA01000053_gene371 6.72e-49 168.0 COG0863@1|root,COG0863@2|Bacteria,1UZIN@1239|Firmicutes,4HU16@91061|Bacilli 91061|Bacilli L DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_356416_2 428125.CLOLEP_01409 2.03e-259 729.0 COG4626@1|root,COG4626@2|Bacteria,1TT9I@1239|Firmicutes,24AFK@186801|Clostridia,3WNF4@541000|Ruminococcaceae 186801|Clostridia S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_356416_5 665956.HMPREF1032_00668 4.34e-28 107.0 2AIHK@1|root,318ZG@2|Bacteria,1V7P0@1239|Firmicutes,24KNU@186801|Clostridia,3WNH7@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_125843_1 691965.D4P7I3_9CAUD 6.75e-164 501.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_137531_1 1476902.A0A097P6S4_9CAUD 2.55e-55 204.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QHYN@10662|Myoviridae 10662|Myoviridae S amidase activity - - - - - - - - - - - - - k59_52681_1 686439.D0U234_9CAUD 5.56e-32 119.0 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales 28883|Caudovirales S HNH endonuclease - - - - - - - - - - - - - k59_246946_2 1692242.A0A0K1RKZ2_9CIRC 3.47e-24 102.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_101430_1 1141136.K4F774_9CAUD 6.02e-08 51.2 4QBNW@10239|Viruses,4QXIZ@35237|dsDNA viruses no RNA stage,4QTQP@28883|Caudovirales,4QJWG@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_101430_2 1283077.M1INZ1_9CAUD 2.09e-22 102.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales,4QNDH@10744|Podoviridae 10744|Podoviridae S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_198394_3 1401067.HMPREF0872_01230 4.5e-22 109.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4H24B@909932|Negativicutes 909932|Negativicutes L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k59_332390_1 77856.REP_BFDV 1.57e-20 91.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_380729_1 1141137.K4F9T6_9CAUD 1.35e-19 99.0 4QB4B@10239|Viruses,4QWC6@35237|dsDNA viruses no RNA stage,4QQNI@28883|Caudovirales,4QNPA@10744|Podoviridae 10744|Podoviridae S Glutamine amidotransferase domain - - - - - - - - - - - - - k59_89227_6 105154.Q9MBU3_9VIRU 5.45e-07 56.6 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_89227_7 1385658.U5KPZ6_9VIRU 1.28e-102 320.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_184962_5 1385658.U5KPZ6_9VIRU 2.1e-188 546.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_174328_1 913865.DOT_1568 3.4e-34 128.0 28MC2@1|root,2ZAQD@2|Bacteria,1VSEU@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - k59_65245_1 439375.Oant_0261 6.12e-38 137.0 COG3179@1|root,COG3179@2|Bacteria,1R71F@1224|Proteobacteria,2V8ZU@28211|Alphaproteobacteria,1J48B@118882|Brucellaceae 28211|Alphaproteobacteria S chitinase - - - - - - - - - - - - - k59_162315_4 645099.MREP_BBTVA 1.22e-09 67.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_28596_3 101510.RHA1_ro11315 1.74e-05 47.4 2CC1Y@1|root,32BRW@2|Bacteria,2HGF4@201174|Actinobacteria,4G4MC@85025|Nocardiaceae 201174|Actinobacteria K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA - - - - - - - - - - - - Whib k59_223243_1 595460.RRSWK_05083 4.62e-72 238.0 COG0582@1|root,COG0582@2|Bacteria,2IYXX@203682|Planctomycetes 203682|Planctomycetes L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k59_163488_5 1609634.A0A0C5AFT2_9VIRU 4.01e-81 255.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_163488_7 1609634.A0A0C5AFV4_9VIRU 2.17e-90 286.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_224489_1 1178537.BA1_18352 2.1e-25 110.0 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1TPHP@1239|Firmicutes,4HC9M@91061|Bacilli,1ZDFY@1386|Bacillus 91061|Bacilli KL DNA methylase - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_139026_2 2003327.CAPSD_BPCHP 3.69e-14 79.3 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_309311_3 1234888.K0A2J2_9VIRU 5e-152 449.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_309311_4 483216.BACEGG_02720 5.42e-10 67.8 2EVUA@1|root,33P81@2|Bacteria,4P82D@976|Bacteroidetes,2FV68@200643|Bacteroidia,4AU6A@815|Bacteroidaceae 976|Bacteroidetes - - - - - - - - - - - - - - - k59_66363_3 1380367.JIBC01000006_gene298 3.11e-70 221.0 2EKAP@1|root,33E0Y@2|Bacteria,1NAAI@1224|Proteobacteria,2UI39@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_66363_4 1166948.JPZL01000002_gene1629 7.52e-23 95.5 2DRN8@1|root,33CCM@2|Bacteria,1NGRN@1224|Proteobacteria 1224|Proteobacteria - - - - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - - k59_66363_6 1217715.F994_02778 3.42e-31 119.0 2EPAR@1|root,33GXH@2|Bacteria,1N7YQ@1224|Proteobacteria,1STFM@1236|Gammaproteobacteria,3NJS2@468|Moraxellaceae 1236|Gammaproteobacteria S RyR domain - - - - - - - - - - - - RyR k59_66363_7 318586.Pden_3765 2.9e-31 113.0 2D1MV@1|root,32TAZ@2|Bacteria,1N45A@1224|Proteobacteria,2UEJT@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage protein (N4 Gp49/phage Sf6 gene 66) family - - - - - - - - - - - - Phage_gp49_66 k59_66363_8 1366050.N234_18785 2.67e-15 77.4 2D0K9@1|root,32T8S@2|Bacteria,1MZRW@1224|Proteobacteria,2VW7X@28216|Betaproteobacteria,1KE19@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_102719_2 1037409.BJ6T_53000 5.85e-25 105.0 COG4675@1|root,COG4675@2|Bacteria,1N9JB@1224|Proteobacteria,2UIAU@28211|Alphaproteobacteria 28211|Alphaproteobacteria S tail collar domain protein - - - - - - - - - - - - - k59_260224_1 1028800.RG540_CH13740 6.37e-153 459.0 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,2TVEI@28211|Alphaproteobacteria,4BIH2@82115|Rhizobiaceae 28211|Alphaproteobacteria L DNA polymerase A domain - - - - - - - - - - - - DNA_pol_A k59_357636_1 1676184.A0A186YBN5_9CIRC 2.61e-35 137.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_345803_2 1492922.GY26_15975 4.38e-28 128.0 COG1196@1|root,COG1511@1|root,COG1196@2|Bacteria,COG1511@2|Bacteria 2|Bacteria Q domain protein - - - ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - DUF349 k59_309443_3 1232427.CAVS020000011_gene1451 5.04e-40 166.0 COG3103@1|root,COG5412@1|root,COG4991@2|Bacteria,COG5412@2|Bacteria,2I5CG@201174|Actinobacteria,22KNY@1653|Corynebacteriaceae 201174|Actinobacteria M heme binding - - - - - - - - - - - - SLT k59_41773_1 1121434.AULY01000011_gene1829 2.98e-06 57.8 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,42YKK@68525|delta/epsilon subdivisions,2WUDS@28221|Deltaproteobacteria,2M8E7@213115|Desulfovibrionales 28221|Deltaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_90901_2 479435.Kfla_1881 0.0006 47.0 COG1621@1|root,COG1621@2|Bacteria 2|Bacteria G Belongs to the glycosyl hydrolase 32 family - - 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 - GH32 - Glyco_hydro_32N,Glyco_hydro_43 k59_102853_1 1618240.A0A0C5IMJ1_9CIRC 2.45e-94 287.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_139185_2 1166018.FAES_1856 3.52e-39 139.0 COG0270@1|root,COG0270@2|Bacteria,4P3WE@976|Bacteroidetes 976|Bacteroidetes L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_382067_2 1123255.JHYS01000005_gene659 1.59e-119 368.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2VNHP@28216|Betaproteobacteria,4AC68@80864|Comamonadaceae 28216|Betaproteobacteria S Terminase - - - - - - - - - - - - Terminase_1 k59_382067_3 945083.W0LM09_9CAUD 1.14e-66 212.0 4QAIJ@10239|Viruses,4QVZ9@35237|dsDNA viruses no RNA stage,4QPXI@28883|Caudovirales,4QM02@10699|Siphoviridae 10699|Siphoviridae S C-5 cytosine-specific DNA methylase - - - - - - - - - - - - - k59_321809_1 438753.AZC_3585 4.9e-38 139.0 28IR7@1|root,2Z8QR@2|Bacteria,1PBTP@1224|Proteobacteria,2U248@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_54090_1 186617.M9M8L2_9VIRU 8.66e-19 90.1 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_359082_2 1618260.A0A0C5I2C5_9CIRC 1.15e-77 243.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_371212_2 1122147.AUEH01000019_gene948 1.78e-07 56.2 COG0740@1|root,COG0740@2|Bacteria,1TR2H@1239|Firmicutes,4HBZH@91061|Bacilli,3F5E9@33958|Lactobacillaceae 91061|Bacilli OU Belongs to the peptidase S14 family - - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease k59_92817_1 1123504.JQKD01000005_gene4830 7.35e-15 71.6 2EN2V@1|root,33FR1@2|Bacteria,1NJXZ@1224|Proteobacteria,2W3KD@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_226379_2 331869.BAL199_07303 2.06e-88 276.0 COG0451@1|root,COG0451@2|Bacteria,1PB4Y@1224|Proteobacteria,2TTV7@28211|Alphaproteobacteria,4BQC1@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria M 3-beta hydroxysteroid dehydrogenase/isomerase family - - - - - - - - - - - - Epimerase k59_226379_3 316055.RPE_1511 4.1e-106 326.0 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,2TRCN@28211|Alphaproteobacteria,3JTVF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - - - - - - - - - - CTP_transf_like,PfkB k59_153151_4 1548905.A0A0A1IV72_9CAUD 1.45e-40 162.0 4QBQM@10239|Viruses,4QPZ5@28883|Caudovirales,4QMBJ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_347389_1 349521.HCH_05649 2.24e-74 262.0 COG4733@1|root,COG4733@2|Bacteria,1MXB4@1224|Proteobacteria,1RRUV@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative phage tail protein - - - - - - - - - - - - Phage-tail_3 k59_274360_1 1609634.A0A0C5AFV4_9VIRU 5.69e-34 129.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_274360_3 1385658.U5KNR1_9VIRU 2.05e-42 153.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_371218_2 1121896.JMLU01000052_gene1259 1.44e-10 62.0 COG3108@1|root,COG3108@2|Bacteria,4P9W9@976|Bacteroidetes,1INI1@117743|Flavobacteriia,2NZQD@237|Flavobacterium 976|Bacteroidetes S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k59_68242_1 1609634.A0A0C5AFV4_9VIRU 4.05e-67 222.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_177719_1 754477.Q7C_824 2.37e-43 150.0 COG0741@1|root,COG0741@2|Bacteria,1R7P8@1224|Proteobacteria,1S3T1@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - - - - - - - - - - SLT k59_130552_2 742733.HMPREF9469_05065 2.31e-46 155.0 2E0G5@1|root,324TP@2|Bacteria,1UQZN@1239|Firmicutes,258ST@186801|Clostridia,222Q1@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_130552_3 691965.D4P7I3_9CAUD 7.52e-188 566.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_312485_3 1385658.U5KPZ6_9VIRU 2.88e-219 624.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_312485_5 1165094.RINTHH_3920 3.51e-71 230.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_337135_1 679926.Mpet_2297 2.01e-20 94.7 COG0863@1|root,arCOG00115@2157|Archaea,2Y00D@28890|Euryarchaeota 28890|Euryarchaeota L modification methylase - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_44993_1 105154.Q9MBU3_9VIRU 5.36e-14 74.7 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_154880_2 626887.J057_01665 1.38e-14 75.1 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,1RR0M@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_275876_2 1283078.M1IDT1_9CAUD 8.32e-09 56.6 4QAV0@10239|Viruses,4QY41@35237|dsDNA viruses no RNA stage,4QSR9@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_69820_3 1327993.S0A180_9CAUD 9.49e-07 58.5 4QFF1@10239|Viruses,4QWNY@35237|dsDNA viruses no RNA stage,4QPE1@28883|Caudovirales,4QN4T@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_263530_5 156889.Mmc1_2604 1.87e-69 229.0 COG1475@1|root,COG4725@1|root,COG1475@2|Bacteria,COG4725@2|Bacteria,1R553@1224|Proteobacteria,2TRP6@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT Belongs to the MT-A70-like family - - - - - - - - - - - - MT-A70 k59_57356_1 395495.Lcho_0484 5.96e-43 159.0 COG2227@1|root,COG2520@1|root,COG2227@2|Bacteria,COG2520@2|Bacteria 2|Bacteria J tRNA (guanine(37)-N(1))-methyltransferase activity - - - - - - - - - - - - Glycos_transf_2,Methyltransf_11,Methyltransf_21,Methyltransf_23,Methyltransf_25 k59_337335_1 32264.tetur04g07920.1 4.42e-07 58.5 COG5271@1|root,KOG1808@2759|Eukaryota,38FBP@33154|Opisthokonta,3BD9P@33208|Metazoa,3CUCR@33213|Bilateria,41V94@6656|Arthropoda 33208|Metazoa S Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits MDN1 GO:0000027,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005829,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0030684,GO:0030687,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045111,GO:0046483,GO:0051082,GO:0065003,GO:0070013,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - ko:K14572 ko03008,map03008 - - - ko00000,ko00001,ko03009 - - - AAA_5,VWA k59_349300_1 521000.PROVRETT_06008 2.69e-140 435.0 28JKJ@1|root,2Z9DD@2|Bacteria,1MUN2@1224|Proteobacteria,1RQIP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage P22-like portal protein - - - - - - - - - - - - P22_portal k59_349300_2 1417599.U6C6Y4_9CAUD 1.96e-40 149.0 4QF87@10239|Viruses,4QYZ4@35237|dsDNA viruses no RNA stage,4QPVW@28883|Caudovirales,4QNV3@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_142573_1 156889.Mmc1_2921 8.24e-06 51.6 28HHC@1|root,2Z7T2@2|Bacteria,1PZ57@1224|Proteobacteria,2U3R2@28211|Alphaproteobacteria 28211|Alphaproteobacteria S AAA domain - - - - - - - - - - - - AAA_24 k59_35143_1 1158292.JPOE01000002_gene2723 1.33e-40 154.0 COG0358@1|root,COG0358@2|Bacteria,1QX15@1224|Proteobacteria,2WH3N@28216|Betaproteobacteria 28216|Betaproteobacteria L Protein of unknown function (DUF3987) - - - - - - - - - - - - DUF3987 k59_302763_6 864702.OsccyDRAFT_4840 9.93e-06 53.9 COG2189@1|root,COG2189@2|Bacteria,1G2XK@1117|Cyanobacteria,1HA14@1150|Oscillatoriales 1117|Cyanobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_326991_1 1385658.U5KPZ6_9VIRU 8.3e-107 328.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_10067_1 1673638.A0A0H4AJL5_9CIRC 1.97e-18 87.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_71389_1 1517681.HW45_08080 5.32e-35 125.0 COG2131@1|root,COG2131@2|Bacteria,1RD1P@1224|Proteobacteria,1T01V@1236|Gammaproteobacteria,1Y2XW@135623|Vibrionales 135623|Vibrionales F MafB19-like deaminase - - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_107579_3 1410634.JHVD01000028_gene2099 7.44e-11 62.8 COG4570@1|root,COG4570@2|Bacteria,2GV9V@201174|Actinobacteria 201174|Actinobacteria L Endodeoxyribonuclease RusA - - - - - - - - - - - - RusA k59_350728_2 1609634.A0A0C5AFT2_9VIRU 5.1e-154 441.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_350728_5 1609634.A0A0C5AFV4_9VIRU 3.26e-277 771.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_350728_6 1609634.A0A0C5ANA6_9VIRU 5.48e-41 145.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_58970_1 428125.CLOLEP_01423 2.72e-36 137.0 2E2JP@1|root,32XP4@2|Bacteria,1VAIM@1239|Firmicutes,24PPR@186801|Clostridia,3WI4W@541000|Ruminococcaceae 186801|Clostridia S Phage tail protein - - - - - - - - - - - - Sipho_tail k59_21256_2 1150626.PHAMO_80072 9.24e-34 138.0 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,2TV42@28211|Alphaproteobacteria,2JXEM@204441|Rhodospirillales 204441|Rhodospirillales S Terminase-like family - - - - - - - - - - - - - k59_168066_1 438753.AZC_0843 1.3e-67 221.0 28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria,2U265@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_119211_1 1280946.HY29_17480 2.32e-23 99.4 COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,2UETF@28211|Alphaproteobacteria,43X2G@69657|Hyphomonadaceae 28211|Alphaproteobacteria E Belongs to the SOS response-associated peptidase family - - - - - - - - - - - - SRAP k59_363527_1 1226322.HMPREF1545_02860 2.84e-08 60.8 COG0863@1|root,COG0863@2|Bacteria,1UK8T@1239|Firmicutes,25FQR@186801|Clostridia 186801|Clostridia L Psort location Cytoplasmic, score - - - - - - - - - - - - N6_N4_Mtase k59_206172_3 105154.Q9MBU6_9VIRU 5.3e-14 72.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_266359_1 2003327.REP_BPCHP 9.95e-06 55.8 4QCVK@10239|Viruses,4QUMV@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_387892_1 744980.TRICHSKD4_2401 2.21e-46 166.0 COG0863@1|root,COG0863@2|Bacteria,1MY4G@1224|Proteobacteria,2U1X0@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_48381_1 1188256.BASI01000003_gene2624 1.54e-07 58.2 COG5281@1|root,COG5283@1|root,COG5281@2|Bacteria,COG5283@2|Bacteria,1QZFN@1224|Proteobacteria,2TYCH@28211|Alphaproteobacteria,3FEMU@34008|Rhodovulum 28211|Alphaproteobacteria D nuclear chromosome segregation - - - - - - - - - - - - - k59_206196_1 313628.LNTAR_03149 1.22e-24 109.0 COG0028@1|root,COG0028@2|Bacteria 2|Bacteria EH Belongs to the TPP enzyme family ilvB2 - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k59_206305_1 1788455.A0A190WHF5_9CIRC 7.06e-40 143.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_352308_1 665950.HMPREF1025_01991 1.32e-23 95.1 2DHA9@1|root,32U8X@2|Bacteria,1VD44@1239|Firmicutes,24NC3@186801|Clostridia 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - - k59_352308_2 691965.D4P7C0_9CAUD 5.94e-53 170.0 4QDUR@10239|Viruses,4QVMY@35237|dsDNA viruses no RNA stage,4QU8R@28883|Caudovirales,4QKNQ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_254859_2 1618236.A0A0C5IB23_9CIRC 7.64e-27 114.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_49347_12 563192.HMPREF0179_03431 1.02e-25 120.0 COG3170@1|root,COG3170@2|Bacteria,1Q45C@1224|Proteobacteria,42Z4T@68525|delta/epsilon subdivisions,2WTRW@28221|Deltaproteobacteria,2MA4T@213115|Desulfovibrionales 28221|Deltaproteobacteria NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - k59_109970_4 293826.Amet_2582 2.33e-12 72.0 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1TPHP@1239|Firmicutes,249MR@186801|Clostridia,36FKT@31979|Clostridiaceae 186801|Clostridia KL Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_109970_7 1327981.S0A1N4_9CAUD 3.74e-33 128.0 4QFGZ@10239|Viruses,4QY9R@35237|dsDNA viruses no RNA stage,4QPY9@28883|Caudovirales,4QMRF@10699|Siphoviridae 10699|Siphoviridae S Phage terminase large subunit - - - - - - - - - - - - - k59_219548_1 1385658.U5KPZ6_9VIRU 8.86e-37 139.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_292374_1 1618254.A0A0C5IBG4_9CIRC 5.59e-74 234.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_377435_7 440250.A5HL26_9CAUD 8.14e-28 119.0 4QBD3@10239|Viruses,4QXFU@35237|dsDNA viruses no RNA stage,4QQ7Z@28883|Caudovirales,4QNJ0@10744|Podoviridae 10744|Podoviridae S P22 coat protein - gene protein 5 - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0009987,GO:0016032,GO:0016043,GO:0019012,GO:0019028,GO:0019030,GO:0019058,GO:0019068,GO:0019069,GO:0019075,GO:0022607,GO:0039620,GO:0042802,GO:0042803,GO:0044085,GO:0044403,GO:0044419,GO:0044423,GO:0046729,GO:0046797,GO:0046983,GO:0051704,GO:0071840 - - - - - - - - - - - k59_207377_3 102125.Xen7305DRAFT_00048590 7.12e-58 189.0 COG1192@1|root,COG1192@2|Bacteria,1G56I@1117|Cyanobacteria,3VM4Z@52604|Pleurocapsales 1117|Cyanobacteria D VirC1 protein - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 k59_146554_1 1197951.I6RT34_9CAUD 2.93e-67 220.0 4QGAG@10239|Viruses,4R0KB@35237|dsDNA viruses no RNA stage,4QUA4@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_146554_2 1161935.H9D1H5_9CAUD 5.91e-167 496.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales,4QNDH@10744|Podoviridae 10744|Podoviridae S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_243543_2 1385658.U5KNR1_9VIRU 1.13e-64 213.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_243543_4 105154.Q9MBU6_9VIRU 4.21e-197 569.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_243543_5 105154.Q9MBU3_9VIRU 1.88e-09 63.2 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_377442_1 1385658.U5KPZ6_9VIRU 6.09e-96 294.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_340808_2 1234888.K0A2J2_9VIRU 3.57e-69 225.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_219605_1 1071679.BG57_03865 1.56e-32 133.0 COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,2VRW1@28216|Betaproteobacteria,1K380@119060|Burkholderiaceae 28216|Betaproteobacteria S phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_219605_2 575589.HMPREF0018_02852 9.16e-48 169.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,1RP8Z@1236|Gammaproteobacteria,3NSV4@468|Moraxellaceae 1236|Gammaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_231563_4 1122164.JHWF01000003_gene2091 3.29e-23 97.4 2D0K9@1|root,32T8S@2|Bacteria,1MZRW@1224|Proteobacteria,1SF0N@1236|Gammaproteobacteria,1JEKY@118969|Legionellales 118969|Legionellales - - - - - - - - - - - - - - - k59_255764_1 909613.UO65_0508 5.05e-08 63.9 COG0553@1|root,COG0553@2|Bacteria,2GISC@201174|Actinobacteria,4E0BN@85010|Pseudonocardiales 201174|Actinobacteria L SNF2 family N-terminal domain - - - - - - - - - - - - HHH_5,Helicase_C,SNF2_N k59_255764_3 469381.Dpep_0394 1.3e-10 63.5 COG0817@1|root,COG0817@2|Bacteria,3TCBE@508458|Synergistetes 508458|Synergistetes L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group - - - - - - - - - - - - - k59_255764_6 1188256.BASI01000001_gene184 2.87e-08 62.0 COG0582@1|root,COG0582@2|Bacteria,1NH8M@1224|Proteobacteria,2TUHG@28211|Alphaproteobacteria,3FEGA@34008|Rhodovulum 28211|Alphaproteobacteria L Phage integrase family - - - - - - - - - - - - Phage_integrase k59_255764_10 548479.HMPREF0573_11260 2.35e-08 63.5 COG0749@1|root,COG0749@2|Bacteria,2IG0A@201174|Actinobacteria,4D4MC@85005|Actinomycetales 201174|Actinobacteria L DNA polymerase - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_61620_1 484770.UFO1_2472 1.15e-07 51.6 28P3F@1|root,32U60@2|Bacteria,1VDW0@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - k59_329294_3 173443.Q8HAF2_BPST6 1.42e-09 59.3 4QD1J@10239|Viruses,4QW7G@35237|dsDNA viruses no RNA stage,4QQDR@28883|Caudovirales,4QNSF@10744|Podoviridae 10744|Podoviridae S Protein of unknown function (DUF1364) - - - - - - - - - - - - - k59_329294_4 398578.Daci_1937 0.000111 45.1 2CHMJ@1|root,33K4J@2|Bacteria,1NQ8Y@1224|Proteobacteria,2W4HB@28216|Betaproteobacteria,4AI7M@80864|Comamonadaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_268531_1 1117943.SFHH103_00150 1.6e-16 84.3 2DPZ1@1|root,3340X@2|Bacteria,1R2EE@1224|Proteobacteria,2TZIB@28211|Alphaproteobacteria,4BP2Q@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_122849_2 1692249.A0A0K1RL40_9CIRC 7.3e-23 104.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_171287_3 1110502.TMO_0047 2.81e-78 266.0 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,2TVGJ@28211|Alphaproteobacteria,2JPR0@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_147112_1 76869.PputGB1_3432 1.4e-10 62.0 2CJKM@1|root,314EI@2|Bacteria,1N8C9@1224|Proteobacteria,1SGI2@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_37658_1 1211777.BN77_4169 5.9e-29 112.0 2C5GI@1|root,2Z8C1@2|Bacteria,1R8XM@1224|Proteobacteria,2TUME@28211|Alphaproteobacteria,4BJKS@82115|Rhizobiaceae 28211|Alphaproteobacteria S P22 coat protein - gene protein 5 - - - - - - - - - - - - P22_CoatProtein k59_305069_1 1054461.G0XNU2_9CAUD 2.42e-42 151.0 4QEG2@10239|Viruses,4QRJ9@28883|Caudovirales,4QP0R@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_305069_2 655097.C8ZKD6_9CAUD 7.67e-56 197.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_62199_2 1379692.S5SXY7_9CIRC 5.47e-14 81.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_86219_1 1379717.S5SY19_9CIRC 2.03e-57 189.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_86219_2 1618236.A0A0C5IB23_9CIRC 2.01e-14 74.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_147184_5 1123242.JH636438_gene5660 1.72e-27 110.0 COG5362@1|root,COG5362@2|Bacteria,2J0FK@203682|Planctomycetes 203682|Planctomycetes S Terminase-like family - - - - - - - - - - - - Terminase_6 k59_207966_5 96561.Dole_2472 2.66e-22 105.0 COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42YHE@68525|delta/epsilon subdivisions,2WUJ7@28221|Deltaproteobacteria 28221|Deltaproteobacteria C Elongator protein 3, MiaB family, Radical SAM - - - - - - - - - - - - Radical_SAM k59_378015_1 13689.BV96_04105 1.1e-37 137.0 28IFN@1|root,2Z8HC@2|Bacteria,1PQ6C@1224|Proteobacteria,2U2GK@28211|Alphaproteobacteria,2K0VI@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - k59_25542_1 487316.BBNM01000011_gene33 1.23e-05 55.1 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,1S0WX@1236|Gammaproteobacteria,3NK4C@468|Moraxellaceae 1236|Gammaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6C k59_74313_1 1692244.A0A0K1RLR5_9CIRC 4.58e-55 186.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_366088_13 1088869.GMO_17650 1.65e-47 159.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2U5BZ@28211|Alphaproteobacteria,2JRQZ@204441|Rhodospirillales 204441|Rhodospirillales L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_366088_19 1410653.JHVC01000023_gene1221 5.92e-05 51.6 COG2188@1|root,COG2188@2|Bacteria,1VG2E@1239|Firmicutes,25EDC@186801|Clostridia,36UM0@31979|Clostridiaceae 186801|Clostridia K PFAM Firmicute plasmid replication protein (RepL) - - - - - - - - - - - - HTH_36 k59_1811_1 1082931.KKY_297 1.38e-51 179.0 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,2TQWC@28211|Alphaproteobacteria,3N7JI@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria L PIF1-like helicase recD - 3.1.11.5 ko:K01144 - - - - ko00000,ko01000 - - - AAA_30,UvrD_C_2 k59_1811_2 43989.cce_4884 4.08e-05 53.9 COG1475@1|root,COG1475@2|Bacteria,1G2ET@1117|Cyanobacteria,3KJPV@43988|Cyanothece 1117|Cyanobacteria K ParB-like nuclease domain - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_183480_1 1121028.ARQE01000006_gene4535 1.34e-05 49.3 28HHC@1|root,2Z7T2@2|Bacteria,1PZ57@1224|Proteobacteria,2U3R2@28211|Alphaproteobacteria 28211|Alphaproteobacteria S AAA domain - - - - - - - - - - - - AAA_24 k59_208691_1 9258.ENSOANP00000025670 9.1e-07 50.8 2BF6Y@1|root,2S16D@2759|Eukaryota,3A216@33154|Opisthokonta,3BQXI@33208|Metazoa,3D8B1@33213|Bilateria,48BMF@7711|Chordata,49B3K@7742|Vertebrata,3JCMZ@40674|Mammalia 33208|Metazoa S taxis LECT2 GO:0001501,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0006935,GO:0007275,GO:0008150,GO:0009605,GO:0009966,GO:0009968,GO:0010646,GO:0010648,GO:0023051,GO:0023057,GO:0030111,GO:0030178,GO:0032501,GO:0032502,GO:0040011,GO:0042221,GO:0042330,GO:0042802,GO:0044421,GO:0044424,GO:0044464,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0065007 - - - - - - - - - - Peptidase_M23 k59_135343_2 2074.JNYD01000019_gene2494 1.99e-31 122.0 COG4653@1|root,COG4653@2|Bacteria,2I9AZ@201174|Actinobacteria 201174|Actinobacteria S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_123543_1 186617.M9M8L2_9VIRU 2.26e-41 151.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_208801_4 1385658.U5KPZ6_9VIRU 1.96e-75 246.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_269153_1 244582.JQAK01000001_gene870 9.06e-12 69.3 2AJ3M@1|root,319N0@2|Bacteria,1Q39Q@1224|Proteobacteria,2UKWC@28211|Alphaproteobacteria,47FRA@766|Rickettsiales 766|Rickettsiales S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 k59_269153_4 1121448.DGI_2053 2.62e-84 267.0 COG4653@1|root,COG4653@2|Bacteria,1MXMN@1224|Proteobacteria,42UKA@68525|delta/epsilon subdivisions,2WQZV@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_257048_1 1232666.JANE01000046_gene1197 1.24e-22 96.7 COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,4HA8G@91061|Bacilli,4GX4Y@90964|Staphylococcaceae 91061|Bacilli H Transaldolase tal - 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA k59_257048_2 643562.Daes_1974 2.15e-06 50.4 COG0451@1|root,COG0451@2|Bacteria,1PB4Y@1224|Proteobacteria,42QBV@68525|delta/epsilon subdivisions,2WQ8F@28221|Deltaproteobacteria,2MB41@213115|Desulfovibrionales 28221|Deltaproteobacteria M 3-beta hydroxysteroid dehydrogenase/isomerase family - - - - - - - - - - - - Epimerase k59_196355_1 1218075.BAYA01000001_gene421 1.05e-38 145.0 28PTM@1|root,2ZCEU@2|Bacteria,1R5DD@1224|Proteobacteria,2W259@28216|Betaproteobacteria 28216|Betaproteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_330645_2 665956.HMPREF1032_00688 4.35e-50 174.0 28K55@1|root,2Z9TX@2|Bacteria,1V0P7@1239|Firmicutes,24DCX@186801|Clostridia,3WK99@541000|Ruminococcaceae 186801|Clostridia S Psort location Cytoplasmic, score 7.50 - - - - - - - - - - - - Sipho_Gp37 k59_2328_2 1434319.W5RV68_9CAUD 7.24e-14 73.9 4QBHW@10239|Viruses,4QW8N@35237|dsDNA viruses no RNA stage,4QTT7@28883|Caudovirales,4QN92@10699|Siphoviridae 10699|Siphoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_2328_4 160488.PP_2268 4.68e-46 154.0 2E0FP@1|root,32W1T@2|Bacteria,1NCZR@1224|Proteobacteria 1224|Proteobacteria L Phage endonuclease I - - - - - - - - - - - - Phage_endo_I k59_221461_1 66269.NL54_17010 5.41e-12 68.2 2CWYZ@1|root,32T0P@2|Bacteria,1MZEM@1224|Proteobacteria,1S9HP@1236|Gammaproteobacteria,3VZKN@53335|Pantoea 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_221461_3 207559.Dde_0905 4.67e-08 57.0 COG1948@1|root,COG1948@2|Bacteria,1N91Q@1224|Proteobacteria,42PBQ@68525|delta/epsilon subdivisions,2WJTC@28221|Deltaproteobacteria,2MABJ@213115|Desulfovibrionales 28221|Deltaproteobacteria L ERCC4 domain - - - - - - - - - - - - ERCC4 k59_51031_2 1379788.I0CKB2_9VIRU 2.42e-34 144.0 4QD5V@10239|Viruses 10239|Viruses S Viral coat protein (S domain) - GO:0003674,GO:0003676,GO:0003723,GO:0005198,GO:0005488,GO:0005509,GO:0005575,GO:0008289,GO:0019012,GO:0019028,GO:0019030,GO:0039617,GO:0039660,GO:0043167,GO:0043169,GO:0044423,GO:0046872,GO:0097159,GO:1901363 - - - - - - - - - - - k59_51031_3 759938.F5BSB4_9CIRC 1.33e-38 148.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_354901_1 765911.Thivi_3526 1.86e-33 127.0 COG0863@1|root,COG0863@2|Bacteria,1R1SY@1224|Proteobacteria,1T59K@1236|Gammaproteobacteria,1X22Z@135613|Chromatiales 135613|Chromatiales L DNA methylase - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_257557_1 515622.bpr_I0423 1.53e-33 128.0 COG0535@1|root,COG0535@2|Bacteria,1UET7@1239|Firmicutes,24F49@186801|Clostridia,4C058@830|Butyrivibrio 186801|Clostridia C Iron-sulfur cluster-binding domain - - - - - - - - - - - - Fer4_12,Radical_SAM,SPASM k59_26694_1 1609634.A0A0C5AFT2_9VIRU 1.54e-20 94.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_63482_1 1029824.AFID01000005_gene785 1.12e-36 145.0 COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria,1W8BX@1268|Micrococcaceae 201174|Actinobacteria L Participates in initiation and elongation during chromosome replication dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3 k59_245188_1 988656.F0V6Y5_9CAUD 2.53e-07 51.6 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_209391_4 1234888.K0A2J2_9VIRU 1.41e-109 341.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_379053_1 745718.JADT01000019_gene1519 6.45e-61 195.0 COG0847@1|root,COG0847@2|Bacteria 2|Bacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease dnaQ - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T k59_2444_1 1437882.AZRU01000008_gene2966 1.24e-32 120.0 2DNA4@1|root,32WDI@2|Bacteria,1RH8K@1224|Proteobacteria,1S8YN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage tail tube, TTP, lambda-like - - - - - - - - - - - - Phage_TTP_11 k59_2444_2 157783.LK03_13395 8.18e-37 128.0 2DM6W@1|root,32UGB@2|Bacteria,1N425@1224|Proteobacteria,1SGA9@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3168) - - - - - - - - - - - - DUF3168 k59_2444_3 1147150.K7PM60_9CAUD 3.77e-32 121.0 4QB1F@10239|Viruses,4QUYH@35237|dsDNA viruses no RNA stage,4QPSW@28883|Caudovirales,4QKPW@10699|Siphoviridae 10699|Siphoviridae S exonuclease activity - - - - - - - - - - - - - k59_2444_4 1538295.JY96_16180 1.39e-42 149.0 COG1442@1|root,COG1442@2|Bacteria,1QH4S@1224|Proteobacteria,2VN0S@28216|Betaproteobacteria,1KN5D@119065|unclassified Burkholderiales 28216|Betaproteobacteria M glycosyl transferase family 8 - - - - - - - - - - - - - k59_318733_2 1357423.S5MQ23_9CAUD 1.73e-09 60.8 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QI6J@10662|Myoviridae 10662|Myoviridae S sequence-specific DNA binding transcription factor activity - - - - - - - - - - - - - k59_51034_2 1788447.A0A190WHJ9_9CIRC 2.71e-58 193.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_210046_1 1123288.SOV_4c02780 1.03e-202 650.0 COG0503@1|root,COG0553@1|root,COG2263@1|root,COG3846@1|root,COG0503@2|Bacteria,COG0553@2|Bacteria,COG2263@2|Bacteria,COG3846@2|Bacteria,1TSYQ@1239|Firmicutes,4H5A6@909932|Negativicutes 909932|Negativicutes F protein secretion by the type IV secretion system - - - - - - - - - - - - SLT k59_222098_1 1609634.A0A0C5ANA6_9VIRU 4.58e-24 102.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_148642_1 1027292.HMPREF9372_2822 1.12e-62 205.0 COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4HA4S@91061|Bacilli,26D77@186818|Planococcaceae 91061|Bacilli D Rod shape-determining protein mreB - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl k59_148642_2 1211035.CD30_13720 7.94e-30 118.0 COG0438@1|root,COG0438@2|Bacteria,1TQN3@1239|Firmicutes,4HCKM@91061|Bacilli 91061|Bacilli M Glycosyl Transferase - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 k59_233919_3 1129374.AJE_04971 8.26e-181 515.0 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RMJ1@1236|Gammaproteobacteria,465SY@72275|Alteromonadaceae 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase k59_233919_6 231434.JQJH01000030_gene1407 1.62e-24 99.0 COG1974@1|root,COG1974@2|Bacteria,1MZFA@1224|Proteobacteria,2UCXW@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT Belongs to the peptidase S24 family umuD - - ko:K03503 - - - - ko00000,ko01000,ko01002,ko03400 - - - Peptidase_S24 k59_233919_8 658187.LDG_5994 4.49e-157 462.0 COG3378@1|root,COG3378@2|Bacteria,1R6CB@1224|Proteobacteria,1S35E@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage plasmid primase P4 family - - - - - - - - - - - - - k59_173178_2 105154.Q9MBU3_9VIRU 2.24e-13 73.6 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_27350_1 1399115.U719_06655 1.99e-18 90.9 COG0507@1|root,COG0507@2|Bacteria,1TQWH@1239|Firmicutes,4HF2Y@91061|Bacilli 91061|Bacilli L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - - - - - - - - - - AAA_30,Terminase_3 k59_306943_3 1788445.A0A190WHA3_9CIRC 8.24e-66 213.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_270272_1 1618248.A0A0C5IB82_9CIRC 3.76e-44 152.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_222167_2 1281779.H009_14713 2.09e-59 224.0 28IJ1@1|root,2Z8K0@2|Bacteria,1R5PC@1224|Proteobacteria,2U0RA@28211|Alphaproteobacteria,4BBHX@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_222167_4 391596.PBAL39_25275 0.000128 54.7 COG0018@1|root,COG3210@1|root,COG3266@1|root,COG4409@1|root,COG0018@2|Bacteria,COG3210@2|Bacteria,COG3266@2|Bacteria,COG4409@2|Bacteria,4NQ80@976|Bacteroidetes 976|Bacteroidetes G Collagen triple helix repeat (20 copies) - - - - - - - - - - - - Collagen k59_319365_2 1487953.JMKF01000053_gene1805 8.26e-26 107.0 COG2251@1|root,COG2251@2|Bacteria,1G03D@1117|Cyanobacteria,1H8MQ@1150|Oscillatoriales 1117|Cyanobacteria S TIGRFAM RecB family nuclease - - - - - - - - - - - - Cas_Cas4,RNase_H_2 k59_14449_3 457398.HMPREF0326_03042 4.72e-27 110.0 2CWYZ@1|root,32T0P@2|Bacteria,1MZEM@1224|Proteobacteria,4337C@68525|delta/epsilon subdivisions,2WXPD@28221|Deltaproteobacteria,2MCUC@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_258211_1 145579.CAPSD_BPPHM 5.73e-48 171.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_379786_3 948071.S4S2J9_9CAUD 6.47e-35 132.0 4QB79@10239|Viruses,4QX2S@35237|dsDNA viruses no RNA stage,4QS2C@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_367262_1 1234664.AMRO01000024_gene1790 2.09e-08 57.8 COG5377@1|root,COG5377@2|Bacteria,1TS2Y@1239|Firmicutes,4HAFK@91061|Bacilli,1WH73@129337|Geobacillus 91061|Bacilli L YqaJ-like viral recombinase domain yqaJ - - - - - - - - - - - YqaJ k59_197943_1 667121.ET1_07_00870 3.06e-18 93.6 COG4626@1|root,COG4626@2|Bacteria,1R2FH@1224|Proteobacteria,1RN1F@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Terminase - - - - - - - - - - - - - k59_14846_2 1437609.BCAL_2091 5.07e-12 70.9 COG0593@1|root,COG0593@2|Bacteria,2GJKI@201174|Actinobacteria,4CZDW@85004|Bifidobacteriales 201174|Actinobacteria L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C k59_52145_1 1589733.A0A0C5AE50_9CAUD 1.95e-14 73.9 4QB5I@10239|Viruses,4QPQ9@28883|Caudovirales,4QII1@10662|Myoviridae 10662|Myoviridae S N-methyltransferase activity - - - - - - - - - - - - - k59_52145_2 864069.MicloDRAFT_00064220 4.48e-06 48.5 COG0863@1|root,COG0863@2|Bacteria,1R7RR@1224|Proteobacteria,2TS8Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase k59_295262_2 32057.KB217478_gene3579 8.67e-05 48.5 COG3409@1|root,COG3409@2|Bacteria,1GGYA@1117|Cyanobacteria,1HT2F@1161|Nostocales 1117|Cyanobacteria M Predicted Peptidoglycan domain - - - - - - - - - - - - PG_binding_1 k59_100917_1 1200557.JHWV01000001_gene289 4.88e-05 53.5 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H206@909932|Negativicutes 909932|Negativicutes L Participates in initiation and elongation during chromosome replication - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_100917_3 504472.Slin_0543 2.37e-33 144.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,47KYI@768503|Cytophagia 976|Bacteroidetes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_149395_2 1609634.A0A0C5ANA6_9VIRU 6.36e-11 67.8 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_39751_3 1033743.CAES01000113_gene1642 1.21e-07 62.4 COG5301@1|root,COG5301@2|Bacteria,1VEZ9@1239|Firmicutes,4HNUH@91061|Bacilli,26TPX@186822|Paenibacillaceae 91061|Bacilli G cellulose 1,4-beta-cellobiosidase activity - - - - - - - - - - - - - k59_332080_2 1123034.JMKP01000004_gene1737 6.39e-13 68.2 2EMSQ@1|root,33FF4@2|Bacteria,1NDKJ@1224|Proteobacteria,1SDC7@1236|Gammaproteobacteria,3NNBI@468|Moraxellaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1064) - - - - - - - - - - - - DUF1064 k59_14930_1 366602.Caul_5348 2.25e-09 64.7 COG4974@1|root,COG4974@2|Bacteria,1MXZX@1224|Proteobacteria,2U0B6@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_1,Phage_integrase k59_161789_7 203119.Cthe_1722 5.25e-43 169.0 COG1372@1|root,COG4626@1|root,COG1372@2|Bacteria,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,248RI@186801|Clostridia,3WHWB@541000|Ruminococcaceae 186801|Clostridia L large subunit - - - - - - - - - - - - Terminase_1 k59_113407_4 1248916.ANFY01000007_gene2173 4.9e-06 48.9 2EDVK@1|root,337QQ@2|Bacteria,1N33T@1224|Proteobacteria,2UDD4@28211|Alphaproteobacteria,2K6R1@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - k59_77145_2 329254.Q2NPF7_9CAUD 1.7e-26 105.0 4QB0U@10239|Viruses,4QZQJ@35237|dsDNA viruses no RNA stage,4QR5X@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_40406_2 1122225.AULQ01000004_gene2180 4.1e-24 95.5 COG1525@1|root,COG1525@2|Bacteria,4NR4U@976|Bacteroidetes,1I3CI@117743|Flavobacteriia 976|Bacteroidetes L Staphylococcal nuclease homologue - - 3.1.31.1 ko:K01174 - - - - ko00000,ko01000 - - - SNase k59_356662_1 1618258.A0A0C5I9K3_9CIRC 4.67e-21 96.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_332586_1 261726.Q6R4V3_9CAUD 7.29e-27 117.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QJPJ@10662|Myoviridae 10662|Myoviridae S N-acetylmuramoyl-L-alanine amidase activity - GO:0005575,GO:0019012 - - - - - - - - - - - k59_247169_2 1618248.A0A0C5IB82_9CIRC 1.1e-18 87.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_15539_1 1788444.A0A190WHB9_9CIRC 1.06e-32 125.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_101673_2 95619.PM1_0217520 1.48e-15 77.0 COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria 1224|Proteobacteria KT HNH endonuclease - - - - - - - - - - - - HNH_3 k59_4513_1 1379708.S5TNB8_9CIRC 1.02e-15 82.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_247173_1 1234888.K0A2J2_9VIRU 1.36e-28 117.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_223346_1 1609634.A0A0C5AFV4_9VIRU 1.93e-124 374.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_235600_1 1609634.A0A0C5AFV4_9VIRU 6.1e-77 248.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_29564_1 1123269.NX02_21990 1.96e-178 501.0 COG0863@1|root,COG0863@2|Bacteria,1NQ2A@1224|Proteobacteria,2UJ12@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase k59_175284_1 511051.CSE_12250 6.7e-06 48.1 COG0234@1|root,COG0234@2|Bacteria 2|Bacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 k59_296596_3 1276246.SCULI_v1c04630 3.35e-46 173.0 COG0714@1|root,COG0714@2|Bacteria,3WTF0@544448|Tenericutes 544448|Tenericutes S AAA domain (dynein-related subfamily) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_5 k59_224007_1 1234888.K0A2J2_9VIRU 1.01e-37 142.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_77811_1 105154.Q9MBU6_9VIRU 2.64e-156 462.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_199348_1 220664.PFL_3787 8.01e-09 59.3 COG3206@1|root,COG3206@2|Bacteria,1ND5H@1224|Proteobacteria,1RNXC@1236|Gammaproteobacteria 1236|Gammaproteobacteria M DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - - - - - - - - - - - - k59_199348_3 1121949.AQXT01000002_gene1040 5.18e-31 113.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2U5BZ@28211|Alphaproteobacteria,43XK6@69657|Hyphomonadaceae 28211|Alphaproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_65933_4 1121289.JHVL01000007_gene2770 1.12e-67 227.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,36DK9@31979|Clostridiaceae 186801|Clostridia L snf2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_66056_1 1121422.AUMW01000021_gene1621 1.08e-19 87.8 COG3108@1|root,COG3409@1|root,COG3108@2|Bacteria,COG3409@2|Bacteria 2|Bacteria M Peptidoglycan-binding domain 1 protein - - 3.4.17.14 ko:K08640 - - - - ko00000,ko01000,ko01002,ko01011 - - - PG_binding_1,Peptidase_M15_3,Transglycosylas k59_77910_1 997884.HMPREF1068_03186 1.49e-34 132.0 COG1783@1|root,COG1783@2|Bacteria,4NHPB@976|Bacteroidetes,2FR95@200643|Bacteroidia,4AP7A@815|Bacteroidaceae 976|Bacteroidetes S Phage terminase, large subunit, PBSX family - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_150839_2 1385658.U5KPZ6_9VIRU 1.09e-210 602.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_150839_3 105154.Q9MBT9_9VIRU 1.82e-13 68.2 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_200190_6 145579.CAPSD_BPPHM 2.75e-60 213.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_139376_1 626887.J057_01705 4.67e-32 127.0 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,1RZ7H@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_54289_1 1618242.A0A0C5IBR9_9CIRC 7.85e-18 84.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_54289_2 1379719.S5TMX6_9CIRC 2.49e-16 82.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_346008_1 1117943.SFHH103_00150 0.000989 48.9 2DPZ1@1|root,3340X@2|Bacteria,1R2EE@1224|Proteobacteria,2TZIB@28211|Alphaproteobacteria,4BP2Q@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_346008_4 1304877.KI519399_gene5000 3.68e-113 357.0 28S81@1|root,2ZEJD@2|Bacteria,1RCNN@1224|Proteobacteria,2UUXX@28211|Alphaproteobacteria,3K50D@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_346008_9 570952.ATVH01000011_gene340 8.14e-21 105.0 COG0503@1|root,COG1040@1|root,COG0503@2|Bacteria,COG1040@2|Bacteria,1QV41@1224|Proteobacteria 1224|Proteobacteria F acetyltransferase - - - - - - - - - - - - - k59_16828_1 234267.Acid_6881 3.53e-10 69.7 COG1361@1|root,COG3534@1|root,COG4625@1|root,COG1361@2|Bacteria,COG3534@2|Bacteria,COG4625@2|Bacteria,3Y354@57723|Acidobacteria 2|Bacteria M PKD domain containing protein - - 3.4.21.50 ko:K01337,ko:K20276,ko:K21449 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko02000 1.B.40.2 - - Autotransporter,DUF4347,Glyco_hydro_43,He_PIG,P_proprotein,Peptidase_S8,TIG k59_224910_1 1279015.KB908456_gene1597 4.29e-05 50.1 COG5301@1|root,COG5301@2|Bacteria,1N4KH@1224|Proteobacteria,1RXZU@1236|Gammaproteobacteria,1Y5J9@135624|Aeromonadales 135624|Aeromonadales S Phage tail-collar fibre protein - - - - - - - - - - - - DUF3751 k59_78708_1 344747.PM8797T_09094 5.93e-40 157.0 COG3420@1|root,COG3420@2|Bacteria,2J2VK@203682|Planctomycetes 203682|Planctomycetes P Right handed beta helix region - - - - - - - - - - - - Beta_helix k59_114823_1 1385658.U5KPZ6_9VIRU 5.82e-54 187.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_309682_3 1609634.A0A0C5AFT2_9VIRU 3.22e-92 284.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_309682_5 1609634.A0A0C5AFV4_9VIRU 7.7e-247 694.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_309682_7 1609634.A0A0C5ANA6_9VIRU 3.62e-19 88.2 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_42085_2 1121459.AQXE01000001_gene2762 1.09e-10 63.9 2BICQ@1|root,32CIU@2|Bacteria,1Q6ZR@1224|Proteobacteria,43726@68525|delta/epsilon subdivisions,2X1TE@28221|Deltaproteobacteria,2MFN8@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_67418_1 105154.Q9MBU3_9VIRU 1.12e-05 47.0 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_67418_2 1609634.A0A0C5AFV4_9VIRU 1.05e-236 669.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_67418_5 1385658.U5KNR1_9VIRU 6.81e-65 214.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_55154_1 999423.HMPREF9161_01433 5.66e-43 147.0 COG0615@1|root,COG0615@2|Bacteria,1UJSU@1239|Firmicutes,4H4AI@909932|Negativicutes 909932|Negativicutes H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose hldE_2 - - - - - - - - - - - CTP_transf_like k59_80095_1 1303518.CCALI_02520 1.5e-08 57.4 COG0464@1|root,COG0464@2|Bacteria 2|Bacteria O ATPase activity ycf46 - 3.6.4.6 ko:K06027 ko04138,ko04721,ko04727,ko04962,map04138,map04721,map04727,map04962 - - - ko00000,ko00001,ko01000,ko04131 1.F.1.1 - - AAA k59_31699_1 438753.AZC_3598 9.42e-116 355.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT52@1224|Proteobacteria,2TVNI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_2 k59_371246_1 1173022.Cri9333_1963 2.78e-32 134.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1G1P1@1117|Cyanobacteria,1H8EM@1150|Oscillatoriales 1117|Cyanobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_140811_9 529818.AMSG_10002T0 2.67e-06 60.8 KOG1215@1|root,KOG3607@1|root,KOG4348@1|root,KOG1215@2759|Eukaryota,KOG3607@2759|Eukaryota,KOG4348@2759|Eukaryota 2759|Eukaryota S negative regulation of transforming growth factor beta1 production KMT2D GO:0000003,GO:0001654,GO:0001667,GO:0001745,GO:0002064,GO:0002065,GO:0002066,GO:0003006,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005938,GO:0006928,GO:0006996,GO:0007010,GO:0007015,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007297,GO:0007298,GO:0007423,GO:0008150,GO:0009653,GO:0009887,GO:0009888,GO:0009987,GO:0010564,GO:0010631,GO:0016020,GO:0016043,GO:0016477,GO:0017124,GO:0019904,GO:0019953,GO:0022412,GO:0022414,GO:0022607,GO:0030029,GO:0030036,GO:0030100,GO:0030154,GO:0030496,GO:0030707,GO:0030855,GO:0032153,GO:0032154,GO:0032155,GO:0032465,GO:0032501,GO:0032502,GO:0032504,GO:0032794,GO:0032879,GO:0034329,GO:0034330,GO:0034332,GO:0034333,GO:0040011,GO:0043062,GO:0043063,GO:0044085,GO:0044421,GO:0044424,GO:0044425,GO:0044444,GO:0044448,GO:0044459,GO:0044464,GO:0044703,GO:0045171,GO:0045177,GO:0045179,GO:0045216,GO:0045807,GO:0048259,GO:0048260,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048592,GO:0048609,GO:0048731,GO:0048749,GO:0048856,GO:0048869,GO:0048870,GO:0050789,GO:0050794,GO:0050839,GO:0051049,GO:0051050,GO:0051128,GO:0051130,GO:0051179,GO:0051302,GO:0051674,GO:0051704,GO:0051726,GO:0060429,GO:0060627,GO:0065007,GO:0071840,GO:0071944,GO:0090130,GO:0090132,GO:0090596,GO:0097435,GO:0098590,GO:0099568,GO:0099738 2.1.1.43,2.7.11.1 ko:K03068,ko:K06261,ko:K06593,ko:K08867,ko:K09187,ko:K12488,ko:K13738,ko:K14972,ko:K20050,ko:K20371 ko00310,ko04144,ko04150,ko04310,ko04512,ko04520,ko04611,ko04640,ko04666,ko04934,ko05100,ko05200,ko05224,ko05225,ko05226,map00310,map04144,map04150,map04310,map04512,map04520,map04611,map04640,map04666,map04934,map05100,map05200,map05224,map05225,map05226 - R03875,R03938,R04866,R04867 RC00003,RC00060,RC00181,RC00496 ko00000,ko00001,ko01000,ko01001,ko01009,ko03000,ko03036,ko04090,ko04131,ko04147,ko04516 - - - Ig_3,Ldl_recept_a,SET,SH3_1,SH3_9,V-set k59_55751_2 370623.Q1WDG8_9CAUD 1.66e-09 59.7 4QFZ8@10239|Viruses,4QX9I@35237|dsDNA viruses no RNA stage,4QSMM@28883|Caudovirales,4QKS6@10699|Siphoviridae 10699|Siphoviridae S Pfam:Terminase_6C - - - - - - - - - - - - - k59_250123_1 1296416.JACB01000003_gene661 1.07e-18 94.7 COG2356@1|root,COG4935@1|root,COG2356@2|Bacteria,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia,2YHVC@290174|Aquimarina 976|Bacteroidetes LO Metallo-peptidase family M12B Reprolysin-like - - - - - - - - - - - - DUF5011,MAM,P_proprotein,Reprolysin_4,fn3 k59_18131_2 1500301.JQMF01000006_gene1755 3.95e-22 96.3 28MSK@1|root,2ZB0X@2|Bacteria,1R7CY@1224|Proteobacteria,2U2MY@28211|Alphaproteobacteria,4BJ92@82115|Rhizobiaceae 28211|Alphaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_214562_1 1244869.H261_08538 4.2e-09 60.8 COG2071@1|root,COG2071@2|Bacteria,1MV8E@1224|Proteobacteria,2TSU3@28211|Alphaproteobacteria,2JPIW@204441|Rhodospirillales 204441|Rhodospirillales S Peptidase C26 - - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 k59_116170_4 269796.Rru_A1278 4.99e-05 46.6 28N1N@1|root,2ZB7Q@2|Bacteria,1R86T@1224|Proteobacteria,2U0A6@28211|Alphaproteobacteria,2JRMI@204441|Rhodospirillales 204441|Rhodospirillales H Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_1 k59_18134_1 654929.REP_PCV1C 1.8e-24 107.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_68224_1 1385658.U5KPZ6_9VIRU 1.17e-105 325.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_68224_5 1385658.U5KNR1_9VIRU 1.14e-46 164.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_68224_7 1609634.A0A0C5AFV4_9VIRU 4.12e-77 249.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_104351_1 145579.CAPSD_BPPHM 2.99e-21 97.8 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_347529_3 667632.KB890187_gene3034 9.54e-14 68.9 COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2VSKJ@28216|Betaproteobacteria,1K8EE@119060|Burkholderiaceae 28216|Betaproteobacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS - - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 k59_177707_1 626418.bglu_1g15460 8.7e-61 191.0 2C5J1@1|root,3067M@2|Bacteria,1N4SF@1224|Proteobacteria,2VWDM@28216|Betaproteobacteria,1K9HT@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_129842_1 1123487.KB892865_gene1394 1.28e-30 123.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,2VMZW@28216|Betaproteobacteria 28216|Betaproteobacteria L DNA polymerase family A - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_275279_1 1211777.BN77_4169 3.46e-72 229.0 2C5GI@1|root,2Z8C1@2|Bacteria,1R8XM@1224|Proteobacteria,2TUME@28211|Alphaproteobacteria,4BJKS@82115|Rhizobiaceae 28211|Alphaproteobacteria S P22 coat protein - gene protein 5 - - - - - - - - - - - - P22_CoatProtein k59_18897_2 1120980.JQKH01000007_gene2612 3.43e-23 97.1 COG3179@1|root,COG3179@2|Bacteria,1R71F@1224|Proteobacteria,2W8UE@28216|Betaproteobacteria,2KR94@206351|Neisseriales 206351|Neisseriales S Chitinase class I - - - - - - - - - - - - Glyco_hydro_19 k59_372158_1 83406.HDN1F_20760 2.64e-11 69.7 COG2718@1|root,COG2718@2|Bacteria,1MWQM@1224|Proteobacteria,1RQWC@1236|Gammaproteobacteria,1J4X8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the UPF0229 family yeaH - - ko:K09786 - - - - ko00000 - - - DUF444 k59_141687_1 675817.VDA_000172 6.37e-12 68.9 COG1961@1|root,COG1961@2|Bacteria,1R3XB@1224|Proteobacteria,1RSC2@1236|Gammaproteobacteria,1XXK6@135623|Vibrionales 135623|Vibrionales L Resolvase, N terminal domain - - - ko:K14060 - - - - ko00000 - - - HTH_7,Resolvase k59_324407_1 2003327.CAPSD_BPCHP 1.06e-22 104.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_336385_2 84588.SYNW0448 2.56e-15 81.6 COG2089@1|root,COG2089@2|Bacteria,1G4IG@1117|Cyanobacteria,1GZZR@1129|Synechococcus 1117|Cyanobacteria M acid synthetase spsE - 2.5.1.101,2.5.1.56 ko:K01654,ko:K18430 ko00520,ko01100,map00520,map01100 - R01804,R04435,R10304 RC00159 ko00000,ko00001,ko01000 - - - AP_endonuc_2,NeuB,SAF k59_311946_1 679926.Mpet_0475 6.39e-26 110.0 COG4983@1|root,arCOG07809@2157|Archaea,2Y47N@28890|Euryarchaeota,2NB1E@224756|Methanomicrobia 224756|Methanomicrobia C Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I) - - - - - - - - - - - - - k59_154199_2 1234888.K0A2J2_9VIRU 2.8e-111 339.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_289327_1 1692249.A0A0K1RLN8_9CIRC 2.26e-33 127.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_251851_1 1052684.PPM_2769 3.65e-41 152.0 COG0507@1|root,COG0507@2|Bacteria,1TQWH@1239|Firmicutes,4HF2Y@91061|Bacilli,26WBJ@186822|Paenibacillaceae 91061|Bacilli L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - - - - - - - - - - - k59_290242_3 1609634.A0A0C5AFV4_9VIRU 9.19e-82 271.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_81985_1 240016.ABIZ01000001_gene59 8.39e-26 104.0 COG0535@1|root,COG0535@2|Bacteria 2|Bacteria I radical SAM domain protein - - - - - - - - - - - - Fer4_14,Radical_SAM,SPASM k59_239448_4 652103.Rpdx1_2528 2.07e-54 199.0 28QU5@1|root,2ZD9H@2|Bacteria,1RAU8@1224|Proteobacteria,2U2GD@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_239448_5 375286.mma_2199 8.35e-42 149.0 2DQXG@1|root,3396G@2|Bacteria,1NE3G@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_239448_9 221360.RS9917_12950 2.99e-34 129.0 COG1442@1|root,COG1442@2|Bacteria,1G3Z0@1117|Cyanobacteria,1GZDJ@1129|Synechococcus 1117|Cyanobacteria M PFAM Glycosyl transferase, family 8 - - - - - - - - - - - - Glyco_transf_8 k59_239448_12 375286.mma_2202 1.19e-110 332.0 28NGF@1|root,2Z9HT@2|Bacteria,1R9QF@1224|Proteobacteria,2VPSU@28216|Betaproteobacteria,47599@75682|Oxalobacteraceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_45331_1 880526.KE386488_gene1769 5.62e-06 55.5 COG1216@1|root,COG1216@2|Bacteria,4P2CG@976|Bacteroidetes,2G0BU@200643|Bacteroidia 976|Bacteroidetes M Glycosyltransferase, group 2 family protein - - - - - - - - - - - - Glycos_transf_2 k59_385021_3 272943.RSP_3793 3.33e-28 106.0 2E6IZ@1|root,33162@2|Bacteria,1N85B@1224|Proteobacteria,2UH5M@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Domain of unknown function (DUF4326) - - - - - - - - - - - - DUF4326 k59_276196_1 440512.C211_04145 1.23e-23 99.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,1SQ0T@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_70115_2 266779.Meso_0224 3.92e-57 191.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,2U0EG@28211|Alphaproteobacteria,43K78@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_203514_1 948071.S4S2D9_9CAUD 5.46e-69 228.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae 10744|Podoviridae S ribonucleoside-triphosphate reductase activity - - - - - - - - - - - - - k59_188370_1 1385658.U5KPZ6_9VIRU 9.8e-74 239.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_337655_1 526225.Gobs_1726 2.04e-16 79.0 COG3409@1|root,COG3409@2|Bacteria 2|Bacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - CHAP,LysM,PG_binding_1,Phage_lysozyme k59_385143_1 649639.Bcell_2106 1.71e-18 97.1 COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HAFE@91061|Bacilli,1ZS5N@1386|Bacillus 91061|Bacilli D Phage tail tape measure protein - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,SLT k59_45498_1 1611039.A0A0C5C3Z3_9CIRC 1.63e-32 132.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_82152_2 1250232.JQNJ01000001_gene3360 1.59e-53 188.0 COG3291@1|root,COG3291@2|Bacteria,4PMR5@976|Bacteroidetes,1IJX3@117743|Flavobacteriia 976|Bacteroidetes N cellulose binding - - - - - - - - - - - - Big_2 k59_179792_1 388399.SSE37_18682 1.5e-29 126.0 COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,2TU4W@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_290925_1 1072685.IX83_07085 6.55e-121 356.0 28HXV@1|root,2Z83C@2|Bacteria,1PJBP@1224|Proteobacteria,2W8RH@28216|Betaproteobacteria,3T5DR@506|Alcaligenaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_131934_1 1122225.AULQ01000001_gene1526 6.53e-10 67.0 COG1345@1|root,COG1361@1|root,COG1404@1|root,COG3227@1|root,COG3897@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG1404@2|Bacteria,COG3227@2|Bacteria,COG3897@2|Bacteria 2|Bacteria P peptidase activity, acting on L-amino acid peptides - - - - - - - - - - - - DUF1573,Laminin_G_3,MAM,Peptidase_M8,SLH k59_118850_1 574376.BAMA_02055 1.4e-37 145.0 COG4983@1|root,COG5519@1|root,COG4983@2|Bacteria,COG5519@2|Bacteria,1TSFH@1239|Firmicutes,4HFH5@91061|Bacilli,1ZD36@1386|Bacillus 91061|Bacilli L Domain of unknown function (DUF927) - - - - - - - - - - - - DUF927 k59_118850_3 1121865.OMW_00687 2.27e-26 103.0 COG1611@1|root,COG1611@2|Bacteria,1V7HV@1239|Firmicutes,4IBV0@91061|Bacilli,4B43C@81852|Enterococcaceae 91061|Bacilli S Belongs to the LOG family - - - - - - - - - - - - - k59_217625_3 1611039.A0A0C5C3Z3_9CIRC 2.17e-08 56.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_9765_1 1165094.RINTHH_3920 1.43e-53 179.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_20897_1 279010.BL03388 0.00012 52.0 COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,4HB9Q@91061|Bacilli,1ZBKA@1386|Bacillus 91061|Bacilli D peptidase - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 k59_70940_1 2003327.CAPSD_BPCHP 4.84e-05 51.6 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_143832_1 1609634.A0A0C5ANA6_9VIRU 1.96e-19 87.8 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_338546_1 753084.F4YCI4_9CAUD 7.5e-24 103.0 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QS4V@28883|Caudovirales,4QKNC@10699|Siphoviridae 10699|Siphoviridae S hydrolase activity - - - - - - - - - - - - - k59_361644_1 1538804.A0A0A1CM43_9CAUD 5.92e-10 65.9 4QB5I@10239|Viruses,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_386052_1 691965.D4P7I3_9CAUD 2.31e-168 514.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_326569_2 1379707.S5SXZ4_9CIRC 0.000642 44.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_118864_1 1123263.AUKY01000086_gene1006 1.08e-40 150.0 28MKK@1|root,2ZAWR@2|Bacteria,1UYAT@1239|Firmicutes,3VSD5@526524|Erysipelotrichia 526524|Erysipelotrichia S Putative viral replication protein - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_189029_2 1234888.K0A2J2_9VIRU 4.42e-119 364.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_277132_1 1165094.RINTHH_3920 2.17e-51 175.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_339470_1 351016.RAZWK3B_17693 7.99e-07 51.2 COG5281@1|root,COG5281@2|Bacteria,1R47M@1224|Proteobacteria,2TUIV@28211|Alphaproteobacteria,2P2ZC@2433|Roseobacter 28211|Alphaproteobacteria S COG5281 Phage-related minor tail protein - - - - - - - - - - - - - k59_339470_2 1035191.HMPREF0185_03072 3.42e-18 85.5 COG5448@1|root,COG5448@2|Bacteria,1MXM8@1224|Proteobacteria,2TTJ3@28211|Alphaproteobacteria,2KH3M@204458|Caulobacterales 204458|Caulobacterales S Conserved hypothetical protein 2217 (DUF2460) - - - - - - - - - - - - DUF2460 k59_205320_2 1618254.A0A0C5IBG4_9CIRC 1.25e-70 224.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_144792_2 665956.HMPREF1032_00689 5.76e-42 149.0 292XD@1|root,2ZQEV@2|Bacteria,1V48I@1239|Firmicutes,24GZD@186801|Clostridia,3WNVV@541000|Ruminococcaceae 186801|Clostridia S COG NOG18825 non supervised orthologous group - - - - - - - - - - - - - k59_339471_1 552811.Dehly_1476 5.08e-73 237.0 COG0064@1|root,COG0064@2|Bacteria,2G62Q@200795|Chloroflexi,34CT7@301297|Dehalococcoidia 301297|Dehalococcoidia J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB - 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey k59_386884_1 1234888.K0A2J2_9VIRU 2.69e-131 396.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_119744_1 1234888.K0A2J2_9VIRU 5.94e-49 173.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_253858_2 1123248.KB893337_gene2377 2.23e-05 54.3 COG2911@1|root,COG2911@2|Bacteria 2|Bacteria S protein secretion - - - ko:K09800 - - - - ko00000,ko02000 - - - TamB k59_181598_2 196162.Noca_3857 5.54e-16 81.3 COG3583@1|root,COG3583@2|Bacteria,2H4RU@201174|Actinobacteria,4DMZZ@85009|Propionibacteriales 201174|Actinobacteria M G5 rlpA - - ko:K21688 - - - - ko00000 - - - DUF348,G5,Transglycosylas k59_362513_1 243164.DET0022 4.84e-33 119.0 2AWTS@1|root,3304E@2|Bacteria,2G9G6@200795|Chloroflexi,34DNE@301297|Dehalococcoidia 301297|Dehalococcoidia S Bacterial PH domain - - - - - - - - - - - - bPH_3 k59_35647_1 411460.RUMTOR_01335 7.96e-73 248.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_218651_1 395019.Bmul_3835 1.33e-11 68.2 COG0338@1|root,COG0338@2|Bacteria,1QZWQ@1224|Proteobacteria 1224|Proteobacteria L DNA N-6-adenine-methyltransferase (Dam) - - - - - - - - - - - - Dam k59_218651_2 1123508.JH636442_gene4486 9.92e-26 112.0 COG3598@1|root,COG3598@2|Bacteria,2J4W0@203682|Planctomycetes 203682|Planctomycetes L AAA domain - - - - - - - - - - - - AAA_25 k59_278212_1 1676184.A0A186YBN5_9CIRC 6.31e-25 107.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_339564_1 322855.Q52PN4_9CAUD 6.75e-27 112.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales 28883|Caudovirales S N-methyltransferase activity - - - - - - - - - - - - - k59_339564_2 646529.Desaci_1279 8.25e-14 68.6 COG1591@1|root,COG1591@2|Bacteria,1V9FG@1239|Firmicutes 1239|Firmicutes L VRR_NUC - - - - - - - - - - - - VRR_NUC k59_168706_1 1609634.A0A0C5AFV4_9VIRU 2.17e-47 170.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_133143_2 314607.KB13_578 2.88e-27 115.0 COG0028@1|root,COG0028@2|Bacteria,1MYUS@1224|Proteobacteria,2VM1Y@28216|Betaproteobacteria,1KR78@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria EH Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k59_189769_1 1692256.A0A0K1RL85_9CIRC 2.21e-21 99.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_206117_1 484895.A9J745_BPLUZ 8.12e-37 143.0 4QAUF@10239|Viruses,4QQIV@28883|Caudovirales,4QNZ6@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_145763_2 460265.Mnod_2507 1.2e-54 186.0 COG3723@1|root,COG3723@2|Bacteria,1R6DB@1224|Proteobacteria,2U82T@28211|Alphaproteobacteria,1JXG9@119045|Methylobacteriaceae 28211|Alphaproteobacteria L PFAM RecT protein - - - ko:K07455 - - - - ko00000,ko03400 - - - RecT k59_254679_2 1692252.A0A0K1RL35_9CIRC 4.48e-93 285.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_266314_1 1286632.P278_33640 5.55e-94 275.0 28HGS@1|root,2Z7SJ@2|Bacteria,4NERU@976|Bacteroidetes,1HZIZ@117743|Flavobacteriia 976|Bacteroidetes S Major spike protein (G protein) - - - - - - - - - - - - Phage_G k59_266314_2 1270196.JCKI01000013_gene3205 0.0 889.0 28IN7@1|root,2Z8NM@2|Bacteria,4NHTH@976|Bacteroidetes 976|Bacteroidetes S Capsid protein (F protein) - - - - - - - - - - - - Phage_F k59_266314_3 1286632.P278_33670 1.35e-19 79.0 2EFW9@1|root,339NJ@2|Bacteria,4P71N@976|Bacteroidetes,1I6VT@117743|Flavobacteriia 976|Bacteroidetes S Microvirus J protein - - - - - - - - - - - - Microvir_J k59_266314_4 1288298.rosmuc_01661 4.9e-103 298.0 28HVF@1|root,2Z81Q@2|Bacteria,1NZPF@1224|Proteobacteria 1224|Proteobacteria S Bacteriophage scaffolding protein D - - - - - - - - - - - - gpD k59_266314_5 1270196.JCKI01000013_gene3202 4.42e-56 174.0 2AGWD@1|root,3174S@2|Bacteria 2|Bacteria S Phage protein C - - - - - - - - - - - - Phage_C k59_266410_3 1238450.VIBNISOn1_1190014 1.38e-14 82.0 2C7BQ@1|root,33MPW@2|Bacteria,1NYCK@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_266410_4 1054968.G0X4U1_9CAUD 3.25e-17 84.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNI0@10744|Podoviridae 10744|Podoviridae S viral capsid - GO:0005575,GO:0019012,GO:0019028,GO:0019030,GO:0039617,GO:0044423,GO:0046729 - - - - - - - - - - - k59_387945_1 1385658.U5KNR1_9VIRU 1.88e-11 65.5 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_352199_1 1033743.CAES01000020_gene3156 4.35e-05 53.1 COG2887@1|root,COG2887@2|Bacteria,1TPIC@1239|Firmicutes,4HCNN@91061|Bacilli,26S2A@186822|Paenibacillaceae 91061|Bacilli L Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_278882_1 213236.Q716P4_9CAUD 0.000145 53.1 4QEZX@10239|Viruses,4R0NF@35237|dsDNA viruses no RNA stage,4QTYH@28883|Caudovirales,4QKMN@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_315727_3 1673638.A0A0H4AJL5_9CIRC 2e-05 49.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_352201_1 862965.PARA_01820 9.92e-29 124.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1Y7ZN@135625|Pasteurellales 135625|Pasteurellales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_352201_3 935836.JAEL01000005_gene2726 1.97e-14 78.2 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4HC9V@91061|Bacilli,1ZQCZ@1386|Bacillus 91061|Bacilli L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,ResIII,SNF2_N k59_376211_1 868864.Dester_0323 1.22e-15 77.4 COG1351@1|root,COG1351@2|Bacteria,2G4CJ@200783|Aquificae 200783|Aquificae H Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 k59_169612_1 145579.B_BPPHM 7.22e-23 94.4 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_120743_1 553220.CAMGR0001_2120 2.24e-14 75.5 29XS6@1|root,30JHZ@2|Bacteria,1Q8JI@1224|Proteobacteria,431U9@68525|delta/epsilon subdivisions,2YSAT@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria - - - - - - - - - - - - - - - k59_376218_1 1286631.X805_04800 1.06e-06 54.3 2CTXP@1|root,32SUA@2|Bacteria,1N1VX@1224|Proteobacteria,2VW3U@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_316465_1 1692255.A0A0K1RL52_9CIRC 3.61e-80 253.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_12574_2 1193181.BN10_1230014 3.59e-08 65.1 COG1674@1|root,COG1716@1|root,COG1674@2|Bacteria,COG1716@2|Bacteria,2GJBR@201174|Actinobacteria,4FF4U@85021|Intrasporangiaceae 201174|Actinobacteria D FtsK/SpoIIIE family - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE,Yop-YscD_cpl k59_97700_2 1234888.K0A2J2_9VIRU 3.92e-54 187.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_207223_1 765910.MARPU_09550 3.52e-09 62.8 COG4653@1|root,COG4653@2|Bacteria,1MWMB@1224|Proteobacteria,1S4MJ@1236|Gammaproteobacteria,1X0RU@135613|Chromatiales 135613|Chromatiales S Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid k59_585_4 105154.Q9MBU3_9VIRU 1.53e-07 57.4 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_255581_2 1165094.RINTHH_3920 9.01e-61 202.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_340616_1 438753.AZC_3598 4.36e-73 238.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1QT52@1224|Proteobacteria,2TVNI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Toprim-like - - 3.6.4.12 ko:K17680 - - - - ko00000,ko01000,ko03029 - - - DnaB_C,Toprim_2 k59_109883_1 1340745.R9TE46_9VIRU 1.07e-136 409.0 4QHQH@10239|Viruses 10239|Viruses S Bacteriophage replication gene A protein (GPA) - - - - - - - - - - - - - k59_267698_1 935548.KI912159_gene123 8.22e-05 49.7 COG4653@1|root,COG4653@2|Bacteria 2|Bacteria G Phage capsid family xkdG - - - - - - - - - - - Phage_capsid k59_267698_2 765910.MARPU_09545 3.23e-28 107.0 2FDNG@1|root,345PN@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_49244_2 640513.Entas_4197 9.1e-05 48.5 COG1670@1|root,COG1670@2|Bacteria,1RC7M@1224|Proteobacteria,1S20T@1236|Gammaproteobacteria,3X2AE@547|Enterobacter 1236|Gammaproteobacteria J Acetyltransferase (GNAT) domain ydaF_2 - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 k59_134073_4 1165094.RINTHH_3920 1.19e-40 149.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_109886_1 1283283.ATXA01000011_gene4642 6.6e-15 76.3 2CHG1@1|root,32YZS@2|Bacteria,2IRMN@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_219412_1 488538.SAR116_0388 1.06e-31 122.0 COG0270@1|root,COG0270@2|Bacteria,1PPPJ@1224|Proteobacteria,2VAY7@28211|Alphaproteobacteria,4BSZM@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria H C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_243362_2 1385658.U5KPZ6_9VIRU 1.57e-86 273.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_49252_1 1986029.Q9MBM3_9VIRU 8.49e-27 108.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_377270_1 77856.REP_BFDV 1.45e-18 87.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_377270_6 1618256.A0A0C5IM93_9CIRC 3.07e-17 86.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_171095_2 1692257.A0A0K1RL39_9CIRC 4.48e-100 302.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_1069_1 756067.MicvaDRAFT_2914 9.99e-12 72.0 COG0438@1|root,COG1215@1|root,COG3914@1|root,COG0438@2|Bacteria,COG1215@2|Bacteria,COG3914@2|Bacteria,1FZUY@1117|Cyanobacteria,1H72J@1150|Oscillatoriales 1117|Cyanobacteria M glycosyl transferase - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_11,Glyco_transf_4,Glyco_transf_41,Glycos_transf_1,Glycos_transf_2,Methyltransf_21,Methyltransf_23,Methyltransf_24 k59_74006_5 1527469.A0A076G6N0_9CAUD 6.95e-19 83.6 4QGDB@10239|Viruses,4QSG0@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_268366_2 1121406.JAEX01000001_gene217 1.65e-19 94.4 COG1783@1|root,COG4626@1|root,COG1783@2|Bacteria,COG4626@2|Bacteria,1QUEN@1224|Proteobacteria,43CQW@68525|delta/epsilon subdivisions,2X7YG@28221|Deltaproteobacteria,2MHAS@213115|Desulfovibrionales 28221|Deltaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - - k59_207766_2 1475143.W8SNN0_9CIRC 3e-34 133.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_304869_1 31535.D4FUM0_BPD3 5.38e-67 229.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_1073_2 205870.Q857K2_BPMB2 1.28e-22 92.4 4QDQK@10239|Viruses,4QWHN@35237|dsDNA viruses no RNA stage,4QSMZ@28883|Caudovirales,4QMPT@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_49753_1 268748.Q58N42_BPPRP 3.08e-15 80.1 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_377836_1 1280692.AUJL01000044_gene2346 1.5e-28 117.0 COG0553@1|root,COG0553@2|Bacteria,1TP2C@1239|Firmicutes,24DVA@186801|Clostridia,36FNM@31979|Clostridiaceae 186801|Clostridia L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_292752_1 765911.Thivi_2368 3.28e-67 231.0 COG3378@1|root,COG4643@1|root,COG3378@2|Bacteria,COG4643@2|Bacteria,1PGQR@1224|Proteobacteria,1T6BM@1236|Gammaproteobacteria,1X1M4@135613|Chromatiales 135613|Chromatiales S Primase C terminal 2 (PriCT-2) - - - ko:K06919 - - - - ko00000 - - - PriCT_2 k59_243947_2 759938.F5BSB4_9CIRC 0.00012 48.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_304898_1 1220601.L7TJ83_9CAUD 8.77e-73 233.0 4QHD0@10239|Viruses,4QXZW@35237|dsDNA viruses no RNA stage,4QUGC@28883|Caudovirales 28883|Caudovirales S T=7 icosahedral viral capsid - GO:0003674,GO:0005488,GO:0005515,GO:0042802 - - - - - - - - - - - k59_353659_1 691965.D4P7D6_9CAUD 7.85e-54 191.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_196127_1 1385658.U5KPZ6_9VIRU 2.09e-75 243.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_50311_4 411901.BACCAC_00254 3.08e-07 60.5 COG3420@1|root,COG3420@2|Bacteria,4NK37@976|Bacteroidetes 976|Bacteroidetes P Right handed beta helix region - - - - - - - - - - - - Beta_helix k59_378291_2 438753.AZC_0843 1.27e-102 313.0 28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria,2U265@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_38051_1 1095747.HMPREF1049_1850 4.55e-45 166.0 COG2887@1|root,COG2887@2|Bacteria,379RI@32066|Fusobacteria 32066|Fusobacteria L Protein of unknown function (DUF2800) - - - - - - - - - - - - DUF2800 k59_38051_3 1122981.AUME01000026_gene550 2.36e-39 157.0 COG0553@1|root,COG0553@2|Bacteria,4NG6P@976|Bacteroidetes,2FPNU@200643|Bacteroidia 976|Bacteroidetes L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_38051_4 1144932.ATTF01000015_gene1210 1.63e-24 100.0 COG0817@1|root,COG0817@2|Bacteria,1NDKU@1224|Proteobacteria 1224|Proteobacteria L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC - 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - - k59_38051_6 1283078.M1IDT1_9CAUD 8.06e-07 52.4 4QAV0@10239|Viruses,4QY41@35237|dsDNA viruses no RNA stage,4QSR9@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_232507_2 1307759.JOMJ01000003_gene1802 5.45e-90 290.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,43BCR@68525|delta/epsilon subdivisions,2X6RN@28221|Deltaproteobacteria,2MA58@213115|Desulfovibrionales 28221|Deltaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_98871_1 1089546.AQUI01000002_gene1320 4.3e-16 86.7 COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria,409T7@622450|Actinopolysporales 201174|Actinobacteria L DnaB-like helicase N terminal domain dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_244424_5 1123269.NX02_21935 2.25e-38 152.0 COG4695@1|root,COG4695@2|Bacteria,1N4JK@1224|Proteobacteria,2U6BJ@28211|Alphaproteobacteria,2K2MZ@204457|Sphingomonadales 204457|Sphingomonadales S Phage portal protein - - - - - - - - - - - - Phage_portal k59_244424_8 1237149.C900_05366 9.11e-11 67.8 COG3740@1|root,COG3740@2|Bacteria,4NDXV@976|Bacteroidetes,47V54@768503|Cytophagia 976|Bacteroidetes S Phage prohead protease, HK97 family - - - - - - - - - - - - Peptidase_S78 k59_244424_9 1121448.DGI_2056 2.54e-72 247.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,42QKN@68525|delta/epsilon subdivisions,2WK3R@28221|Deltaproteobacteria,2MA6M@213115|Desulfovibrionales 28221|Deltaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_281727_2 1121943.KB900010_gene2723 3.92e-12 68.6 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,1S6BA@1236|Gammaproteobacteria,1XM9H@135619|Oceanospirillales 135619|Oceanospirillales G Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_220689_1 1379725.S5SYG4_9CIRC 1.14e-28 115.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_378898_3 2423.NA23_0202780 6.28e-19 92.0 COG1573@1|root,COG1573@2|Bacteria,2GCA2@200918|Thermotogae 200918|Thermotogae L Uracil-DNA glycosylase - GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_342461_1 1105367.CG50_10605 4.19e-15 87.0 COG2304@1|root,COG2304@2|Bacteria,1QWI7@1224|Proteobacteria,2TY8F@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Putative phage tail protein - - - - - - - - - - - - Phage-tail_3,VWA k59_111643_1 1122201.AUAZ01000017_gene2947 5.94e-32 126.0 COG0749@1|root,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,465DD@72275|Alteromonadaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - - - - - - - - - - - DNA_pol_A k59_306166_2 1313421.JHBV01000049_gene74 6.87e-52 187.0 COG3864@1|root,COG3864@2|Bacteria,4NZN2@976|Bacteroidetes 976|Bacteroidetes S VWA-like domain (DUF2201) - - - - - - - - - - - - DUF2201,DUF2201_N k59_306166_3 743966.MYB_00585 1.99e-18 87.8 COG0692@1|root,COG0692@2|Bacteria,3WTJA@544448|Tenericutes 544448|Tenericutes L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung - 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_306166_13 1327990.S0A384_9CAUD 3.63e-37 148.0 4QAW1@10239|Viruses,4QWUW@35237|dsDNA viruses no RNA stage,4QR8A@28883|Caudovirales,4QNCV@10744|Podoviridae 10744|Podoviridae S nucleic acid binding - - - - - - - - - - - - - k59_233150_1 1385658.U5KPZ6_9VIRU 1.72e-202 578.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_233150_3 1165094.RINTHH_3920 5.18e-64 208.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_233150_6 105154.Q9MBU3_9VIRU 7.76e-18 84.3 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_233150_7 1986029.Q9MBM8_9VIRU 1.94e-26 107.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_233259_1 691965.D4P7L7_9CAUD 4.82e-56 199.0 4QB9J@10239|Viruses,4QXFE@35237|dsDNA viruses no RNA stage,4QS1Z@28883|Caudovirales,4QN8F@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_99589_1 744979.R2A130_3480 3.23e-10 62.4 COG4725@1|root,COG4725@2|Bacteria,1R553@1224|Proteobacteria,2TRP6@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT Belongs to the MT-A70-like family - - - - - - - - - - - - MT-A70 k59_124256_2 205914.HS_1385 5.19e-55 192.0 COG1783@1|root,COG1783@2|Bacteria,1RAGC@1224|Proteobacteria 1224|Proteobacteria S phage Terminase large subunit - - - - - - - - - - - - - k59_343128_1 2003327.CAPSD_BPCHP 2.02e-66 221.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_294701_1 1234888.K0A2J2_9VIRU 5.18e-55 190.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_197510_1 438482.A4ZRC7_9CAUD 9.83e-23 106.0 4QNBD@10744|Podoviridae 10744|Podoviridae S outer membrane - - - - - - - - - - - - - k59_245961_1 82995.CR62_16610 4.4e-10 62.4 COG0817@1|root,COG0817@2|Bacteria,1NDKU@1224|Proteobacteria,1SNR9@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group - - - - - - - - - - - - - k59_319382_1 44251.PDUR_04520 2.08e-06 55.5 28JC4@1|root,2Z96S@2|Bacteria,1TS1K@1239|Firmicutes,4HDVZ@91061|Bacilli,26WIC@186822|Paenibacillaceae 91061|Bacilli S P22 coat protein - gene protein 5 - - - - - - - - - - - - P22_CoatProtein k59_124954_2 1692244.A0A0K1RLR5_9CIRC 1.83e-21 94.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_270283_1 680198.SCAB_32881 8.48e-16 80.5 2EB9A@1|root,3359T@2|Bacteria,2INFV@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_270283_2 679201.HMPREF9334_01066 1.78e-20 91.3 COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4H2DZ@909932|Negativicutes 909932|Negativicutes E Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - RadC k59_307112_1 521674.Plim_4265 2.6e-08 65.5 29XN2@1|root,30JDF@2|Bacteria,2J498@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_245967_2 716928.AJQT01000109_gene1217 2.34e-15 75.5 2FEUE@1|root,346TC@2|Bacteria,1MZPB@1224|Proteobacteria,2UC4Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_136660_5 460265.Mnod_3535 4.57e-06 57.8 COG0741@1|root,COG0741@2|Bacteria 2|Bacteria M lytic transglycosylase activity yjbJ - - - - - - - - - - - SLT k59_136660_15 339671.Asuc_0051 2.81e-08 52.0 COG1551@1|root,COG1551@2|Bacteria,1N6PG@1224|Proteobacteria,1SCB4@1236|Gammaproteobacteria,1Y989@135625|Pasteurellales 135625|Pasteurellales J Could accelerate the degradation of some genes transcripts potentially through selective RNA binding csrA - - ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 - - - ko00000,ko00001,ko03019 - - - CsrA k59_136660_17 557598.LHK_01497 4.11e-12 67.4 COG5377@1|root,COG5377@2|Bacteria,1QXZ4@1224|Proteobacteria 1224|Proteobacteria L YqaJ-like viral recombinase domain - - - - - - - - - - - - YqaJ k59_39292_2 1056816.JAFQ01000004_gene4349 2.7e-14 72.8 2E1PK@1|root,32X02@2|Bacteria,2GUS8@201174|Actinobacteria,4G11C@85025|Nocardiaceae 201174|Actinobacteria S Protein of unknown function (DUF1353) - - - - - - - - - - - - DUF1353 k59_136663_1 1692250.A0A0K1RLR1_9CIRC 2.37e-69 220.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_356140_2 906968.Trebr_0725 0.000369 44.3 COG0739@1|root,COG0739@2|Bacteria,2J5FR@203691|Spirochaetes 203691|Spirochaetes M LysM domain M23 M37 peptidase domain protein - - - - - - - - - - - - LysM,Peptidase_M23 k59_125602_2 1341151.ASZU01000008_gene1531 2.35e-13 79.0 COG1783@1|root,COG1783@2|Bacteria,1VK0H@1239|Firmicutes,4HQ2H@91061|Bacilli 91061|Bacilli S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_88928_1 1234888.K0A2J2_9VIRU 1.6e-42 157.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_113006_2 1283078.M1IPK7_9CAUD 3.23e-05 51.6 4QAM2@10239|Viruses,4QV3W@35237|dsDNA viruses no RNA stage,4QPGK@28883|Caudovirales,4QNW0@10744|Podoviridae 10744|Podoviridae S exonuclease activity - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - - - - - - - - - - - k59_28129_1 1321786.HMPREF1992_01500 1.12e-35 140.0 COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,4H2RV@909932|Negativicutes 909932|Negativicutes U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA - - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k59_15065_1 1297863.APJF01000020_gene2704 2.49e-16 90.9 28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TURR@28211|Alphaproteobacteria,3JUCC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_332256_1 225937.HP15_1957 7.45e-32 123.0 29UKS@1|root,30FY7@2|Bacteria,1RGKW@1224|Proteobacteria,1SKMS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_64861_2 77856.REP_BFDV 7.34e-43 155.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_258787_1 743720.Psefu_1425 1.05e-16 81.6 COG1896@1|root,COG1896@2|Bacteria,1RACF@1224|Proteobacteria 1224|Proteobacteria S hydrolases of HD superfamily yfdR GO:0002953,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897 - ko:K06952 - - - - ko00000 - - - - k59_356149_1 1692257.A0A0K1RL39_9CIRC 5.98e-45 158.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_356149_3 1618248.A0A0C5IB82_9CIRC 5.22e-41 144.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_4082_1 1609634.A0A0C5AFV4_9VIRU 4.17e-63 211.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_113017_1 1210884.HG799462_gene9097 6.49e-65 210.0 arCOG07040@1|root,33NW5@2|Bacteria 2|Bacteria S Gene 88 protein - - - - - - - - - - - - GP88 k59_258904_2 1234888.K0A2J2_9VIRU 6.73e-31 122.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_344068_1 1385658.U5KNR1_9VIRU 2.42e-51 174.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_174912_1 444875.E3SMD8_9CAUD 3.23e-77 234.0 4QD0J@10239|Viruses,4R0A5@35237|dsDNA viruses no RNA stage,4QSK9@28883|Caudovirales,4QNR4@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_247426_1 1618247.A0A0C5I2K0_9CIRC 1.69e-21 100.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_185316_1 574376.BAMA_15745 4.41e-14 78.2 COG5280@1|root,COG5412@1|root,COG5280@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HGP4@91061|Bacilli,1ZBH7@1386|Bacillus 91061|Bacilli D minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_29092_1 1618238.A0A0C5IB41_9CIRC 3.12e-30 124.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_296190_2 1150991.H9NBY0_9CAUD 4.79e-15 86.3 4QCHR@10239|Viruses,4QVIA@35237|dsDNA viruses no RNA stage,4QPSF@28883|Caudovirales,4QKFB@10662|Myoviridae 10662|Myoviridae S Mycoplasma protein of unknown function, DUF285 - - - - - - - - - - - - - k59_113631_33 1283287.KB822575_gene553 3.45e-15 90.5 COG1472@1|root,COG3942@1|root,COG1472@2|Bacteria,COG3942@2|Bacteria,2GJ5H@201174|Actinobacteria,4DTG7@85009|Propionibacteriales 201174|Actinobacteria G Carbohydrate binding domain (family 11) - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Big_3_5,CBM_11,Calx-beta,F5_F8_type_C,Glyco_hydro_3,Glyco_hydro_3_C k59_113631_39 113395.AXAI01000002_gene5437 5.11e-51 179.0 28PTM@1|root,2ZCEU@2|Bacteria,1R5DD@1224|Proteobacteria,2TVG7@28211|Alphaproteobacteria,3JU4C@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_113631_45 348824.LPU83_1721 8.5e-113 353.0 COG0507@1|root,COG0507@2|Bacteria,1R1AT@1224|Proteobacteria,2U1ZX@28211|Alphaproteobacteria,4BAYZ@82115|Rhizobiaceae 28211|Alphaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - - - - - - - - - - Terminase_6 k59_4887_1 1197951.I6RT34_9CAUD 4.41e-93 288.0 4QGAG@10239|Viruses,4R0KB@35237|dsDNA viruses no RNA stage,4QUA4@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_259545_3 445970.ALIPUT_01612 3.19e-31 122.0 COG0270@1|root,COG0270@2|Bacteria,4NJPP@976|Bacteroidetes,2FKYT@200643|Bacteroidia 976|Bacteroidetes H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_127035_1 1122962.AULH01000017_gene98 0.000855 49.7 COG4678@1|root,COG4678@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - PhageMin_Tail k59_224436_1 1234888.K0A2J2_9VIRU 6.32e-25 108.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_175779_2 388399.SSE37_25343 5.55e-36 140.0 COG0616@1|root,COG0616@2|Bacteria,1QGPW@1224|Proteobacteria,2U2TT@28211|Alphaproteobacteria 28211|Alphaproteobacteria OU COG0616 periplasmic serine proteases (ClpP class) - - - - - - - - - - - - Peptidase_S49 k59_163508_2 105154.Q9MBU6_9VIRU 1.41e-136 410.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_357557_2 314232.SKA53_04313 6.98e-12 64.7 2EHGS@1|root,33B8Q@2|Bacteria,1NJUU@1224|Proteobacteria,2UM8J@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_41620_1 942016.E9NIG9_9CAUD 3.56e-24 103.0 4QEG2@10239|Viruses,4QVSD@35237|dsDNA viruses no RNA stage,4QRJ9@28883|Caudovirales,4QP0R@10744|Podoviridae 10744|Podoviridae S exonuclease activity - - - - - - - - - - - - - k59_41620_2 1122201.AUAZ01000017_gene2947 2.94e-46 169.0 COG0749@1|root,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,465DD@72275|Alteromonadaceae 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - - - - - - - - - - - DNA_pol_A k59_272724_1 716928.AJQT01000109_gene1178 1.97e-34 130.0 COG0553@1|root,COG0553@2|Bacteria,1R7CK@1224|Proteobacteria,2U228@28211|Alphaproteobacteria,4BN0G@82115|Rhizobiaceae 28211|Alphaproteobacteria KL DNA methylase N-4 - - - - - - - - - - - - Helicase_C,N6_N4_Mtase k59_272724_2 394503.Ccel_3059 2.35e-30 116.0 COG0863@1|root,COG0863@2|Bacteria,1UZIN@1239|Firmicutes,24CGS@186801|Clostridia,36H80@31979|Clostridiaceae 186801|Clostridia L Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase k59_297191_1 34007.IT40_07655 3.48e-05 52.4 2CV95@1|root,32SX6@2|Bacteria,1N2KM@1224|Proteobacteria,2UEE5@28211|Alphaproteobacteria,2PWVC@265|Paracoccus 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_139083_1 1234888.K0A2J2_9VIRU 1.25e-75 249.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_333656_2 553217.ENHAE0001_2186 3.19e-55 191.0 28J3M@1|root,2Z8ZT@2|Bacteria,1Q2A4@1224|Proteobacteria,1RSHA@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_260267_1 278957.ABEA03000120_gene1182 2.04e-16 89.7 COG4733@1|root,COG4733@2|Bacteria,46YHY@74201|Verrucomicrobia,3K9MG@414999|Opitutae 414999|Opitutae S cellulase activity - - - - - - - - - - - - - k59_322373_1 1385658.U5KPZ6_9VIRU 5.19e-60 204.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_6269_1 1234888.K0A2J2_9VIRU 3e-43 159.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_139764_1 186617.M9M8L2_9VIRU 3.47e-44 159.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_346313_1 105154.Q9MBU6_9VIRU 3.54e-59 200.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_236670_1 1249997.JHZW01000003_gene3734 1.62e-08 65.1 COG1511@1|root,COG3210@1|root,COG1511@2|Bacteria,COG3210@2|Bacteria,4PKI0@976|Bacteroidetes,1IKUE@117743|Flavobacteriia,2PI31@252356|Maribacter 976|Bacteroidetes U PFAM Collagen triple helix repeat (20 copies) - - - - - - - - - - - - - k59_236670_4 391587.KAOT1_22616 3.47e-05 48.1 COG0018@1|root,COG3210@1|root,COG0018@2|Bacteria,COG3210@2|Bacteria,4PKDA@976|Bacteroidetes 976|Bacteroidetes J domain, Protein - - - - - - - - - - - - - k59_287258_1 759938.F5BSB4_9CIRC 7.64e-08 60.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_225271_1 1618247.A0A0C5I2K0_9CIRC 8.6e-51 172.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_139776_1 1121937.AUHJ01000007_gene1948 1.54e-07 59.3 COG2911@1|root,COG3941@1|root,COG2911@2|Bacteria,COG3941@2|Bacteria,1MZWI@1224|Proteobacteria,1S51D@1236|Gammaproteobacteria,4682G@72275|Alteromonadaceae 1236|Gammaproteobacteria D Mu-like prophage protein - - - - - - - - - - - - - k59_273404_1 398511.BpOF4_20894 9.64e-07 60.1 COG4548@1|root,COG4548@2|Bacteria 2|Bacteria P von Willebrand factor (vWF) type A domain norD - - ko:K02448 - - R00294 RC02794 ko00000 3.D.4.10 - - VWA,VWA_2 k59_382517_2 105154.Q9MBU3_9VIRU 3.48e-12 70.9 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_334325_1 1465639.A0A060BR41_9CAUD 3.51e-42 145.0 4QAUS@10239|Viruses,4QURX@35237|dsDNA viruses no RNA stage,4QQ2S@28883|Caudovirales,4QNNP@10744|Podoviridae 10744|Podoviridae S flavin adenine dinucleotide binding - - - - - - - - - - - - - k59_346415_4 349161.Dred_0504 2.46e-12 66.2 COG4570@1|root,COG4570@2|Bacteria,1UDK7@1239|Firmicutes,24T1T@186801|Clostridia,266IZ@186807|Peptococcaceae 186801|Clostridia L PFAM Endodeoxyribonuclease - - 3.1.22.4 ko:K01160 - - - - ko00000,ko01000,ko03400 - - - RusA k59_6354_1 691965.D4P7D6_9CAUD 3.5e-97 313.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_6354_4 742740.HMPREF9474_02267 7.47e-63 202.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia,221N8@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_6354_6 1537917.JU82_06570 2.67e-36 130.0 2CGG9@1|root,2ZVSJ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_103490_2 76114.ebA7273 2.24e-73 230.0 28J67@1|root,2Z91Y@2|Bacteria,1R7RG@1224|Proteobacteria,2VRTM@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_322489_1 145579.CAPSD_BPPHM 5.19e-33 132.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_127993_1 1046714.AMRX01000006_gene3195 2.47e-95 300.0 COG4626@1|root,COG4626@2|Bacteria 2|Bacteria S Terminase - - - - - - - - - - - - Terminase_1 k59_274279_1 795666.MW7_1621 2.13e-11 70.5 COG1511@1|root,COG2911@1|root,COG5283@1|root,COG1511@2|Bacteria,COG2911@2|Bacteria,COG5283@2|Bacteria,1QU6S@1224|Proteobacteria,2VRU1@28216|Betaproteobacteria 28216|Betaproteobacteria D tail tape measure protein - - - - - - - - - - - - - k59_92728_3 1207063.P24_17147 6.76e-11 61.6 2AGRP@1|root,316ZH@2|Bacteria,1PY7M@1224|Proteobacteria,2UZ6S@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_177484_1 1486472.A0A068F1U8_9CAUD 7.65e-75 238.0 4QATB@10239|Viruses,4QVUZ@35237|dsDNA viruses no RNA stage,4QPGA@28883|Caudovirales 28883|Caudovirales S Phosphoadenosine phosphosulfate reductase family - - - - - - - - - - - - - k59_115994_2 1236501.BAJU01000020_gene1989 2.09e-08 55.1 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,2TV42@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Terminase large subunit - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_347337_2 1210884.HG799466_gene12928 1.05e-06 50.4 2EUJ6@1|root,33N15@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_311058_6 585502.HMPREF0645_2521 2.3e-08 56.6 2DP7B@1|root,330UW@2|Bacteria,4PN05@976|Bacteroidetes,2G0NB@200643|Bacteroidia 976|Bacteroidetes S Domain of unknown function (DUF4406) - - - - - - - - - - - - DUF4406 k59_335501_1 411460.RUMTOR_01335 5.24e-61 213.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_104306_1 330214.NIDE1274 1.25e-21 100.0 COG4974@1|root,COG4974@2|Bacteria,3J1FQ@40117|Nitrospirae 40117|Nitrospirae L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k59_237684_1 382245.ASA_0158 0.000861 47.0 COG1442@1|root,COG1442@2|Bacteria,1N9H7@1224|Proteobacteria,1RQGY@1236|Gammaproteobacteria,1Y65T@135624|Aeromonadales 135624|Aeromonadales M Glycosyl transferase family 8 - - - - - - - - - - - - Glyco_transf_8 k59_129000_1 291112.PAU_03129 1.18e-19 87.0 COG3756@1|root,COG3756@2|Bacteria,1R5PT@1224|Proteobacteria,1S00W@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein involved in DNA replication initiation, regulation of DNA replication, viral process and DNA replication ydaU - - - - - - - - - - - DUF1376,Phage_rep_O k59_140861_1 1609634.A0A0C5AFV4_9VIRU 1.23e-39 149.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_371304_2 1122970.AUHC01000004_gene2113 2.99e-34 123.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2U5BZ@28211|Alphaproteobacteria,2K464@204457|Sphingomonadales 204457|Sphingomonadales L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_153986_2 1449351.RISW2_23965 5.53e-31 117.0 2CWYZ@1|root,32T0P@2|Bacteria,1MZEM@1224|Proteobacteria,2UCCZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_80931_3 105154.Q9MBU3_9VIRU 3.97e-15 77.8 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_80931_4 105154.Q9MBU6_9VIRU 4.13e-71 231.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_359863_3 1692253.A0A0K1RLM4_9CIRC 1.67e-41 154.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_165877_1 1165094.RINTHH_3920 8.64e-39 140.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_154141_1 1541960.KQ78_01770 0.000604 43.1 2DSCN@1|root,33FJ2@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_384053_1 1452718.JBOY01000137_gene1482 7.05e-36 140.0 COG3170@1|root,COG3170@2|Bacteria 2|Bacteria NU translation initiation factor activity - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - DUF5067,P22_portal,Pkinase k59_116898_2 1449347.JQLN01000004_gene7028 2.41e-08 65.5 2EK6T@1|root,33DX6@2|Bacteria,2IQ75@201174|Actinobacteria,2M5S0@2063|Kitasatospora 201174|Actinobacteria S Pectate lyase superfamily protein - - - - - - - - - - - - Pectate_lyase_3 k59_250870_1 1096546.WYO_0193 1.1e-109 328.0 28JC4@1|root,2Z96S@2|Bacteria,1RI8W@1224|Proteobacteria 1224|Proteobacteria S P22 coat protein-protein 5 domain protein - - - - - - - - - - - - - k59_18841_3 1692242.A0A0K1RKZ2_9CIRC 1.16e-32 128.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_44298_1 642492.Clole_0830 6.61e-39 150.0 COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes 1239|Firmicutes D Phage tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail k59_178551_1 1200557.JHWV01000001_gene264 2.43e-09 65.1 2DBPZ@1|root,2ZABJ@2|Bacteria,1VJIG@1239|Firmicutes,4H5QI@909932|Negativicutes 909932|Negativicutes - - - - - - - - - - - - - - - k59_348383_4 1385658.U5KPZ6_9VIRU 5.4e-204 585.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_324347_1 1454007.JAUG01000005_gene2805 0.000124 45.8 COG0270@1|root,COG0270@2|Bacteria,4NJPP@976|Bacteroidetes,1IYYG@117747|Sphingobacteriia 976|Bacteroidetes L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_359870_1 1358423.N180_02870 4.44e-08 57.4 2DEUM@1|root,2ZPBE@2|Bacteria,4P78P@976|Bacteroidetes,1IZYU@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_359870_2 1497679.EP56_02095 3.24e-09 59.7 2EGZP@1|root,33ART@2|Bacteria 2|Bacteria S YopX protein - - - - - - - - - - - - YopX k59_129887_2 691965.D4P7L6_9CAUD 1.02e-49 163.0 4QFKG@10239|Viruses,4QV77@35237|dsDNA viruses no RNA stage,4QR6Q@28883|Caudovirales,4QMGT@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_155188_1 691965.D4P7I3_9CAUD 8.34e-81 272.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_82009_1 1304876.AZVC01000011_gene3626 3.41e-08 53.1 2CHN5@1|root,2ZU5I@2|Bacteria,2H9V8@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_94903_1 105154.Q9MBU3_9VIRU 1.56e-10 64.7 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_301290_2 1304885.AUEY01000070_gene1852 1.73e-31 118.0 2EB1Y@1|root,3352R@2|Bacteria,1NASI@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_94904_1 230158.Q7Y5X7_9CAUD 2.73e-41 149.0 4QAQE@10239|Viruses,4QUYF@35237|dsDNA viruses no RNA stage,4QPDM@28883|Caudovirales,4QI35@10662|Myoviridae 10662|Myoviridae S DNA integration - - - - - - - - - - - - - k59_69986_1 1411685.U062_00586 3.36e-08 53.9 COG0433@1|root,COG0433@2|Bacteria,1QTVP@1224|Proteobacteria,1T1IQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) - - - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_69986_8 232346.JHQL01000009_gene2032 9.19e-56 190.0 2D784@1|root,32TNH@2|Bacteria,1N098@1224|Proteobacteria,1SDM3@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_117889_1 1211813.CAPH01000015_gene735 0.000177 43.9 COG4123@1|root,COG4123@2|Bacteria,4NIA1@976|Bacteroidetes,2G2ZH@200643|Bacteroidia 976|Bacteroidetes S DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_312802_1 1234888.K0A2J2_9VIRU 1.8e-21 95.9 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_251998_1 1280664.AUIX01000014_gene3579 1.08e-06 56.6 COG4641@1|root,COG4641@2|Bacteria,1VQPW@1239|Firmicutes,25KMM@186801|Clostridia,4BY3Q@830|Butyrivibrio 186801|Clostridia S Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_2 k59_33787_1 926550.CLDAP_22220 4.33e-12 73.2 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2G5J0@200795|Chloroflexi 200795|Chloroflexi L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_57704_1 1173762.S4TP28_9CAUD 1.05e-160 480.0 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_57704_2 1406780.U5PW40_9CAUD 3.82e-69 219.0 4QEMD@10239|Viruses,4R0JN@35237|dsDNA viruses no RNA stage,4QUGF@28883|Caudovirales,4QNXF@10744|Podoviridae 10744|Podoviridae S AAA domain - - - - - - - - - - - - - k59_180869_1 1196324.A374_09423 1.39e-26 114.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli 91061|Bacilli L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k59_132144_1 1123508.JH636442_gene4470 3.23e-23 98.2 COG3087@1|root,COG3087@2|Bacteria,2IX3F@203682|Planctomycetes 203682|Planctomycetes D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - - - - - - - - - - - k59_21047_2 1499967.BAYZ01000154_gene1524 1.37e-12 66.6 COG2230@1|root,COG2230@2|Bacteria,2NQ94@2323|unclassified Bacteria 2|Bacteria M Mycolic acid cyclopropane synthetase cfa - 2.1.1.317,2.1.1.79 ko:K00574,ko:K20238 - - - - ko00000,ko01000 - - - CMAS k59_96345_1 330779.Saci_1721 7.85e-05 46.6 COG0328@1|root,arCOG02942@2157|Archaea,2XR72@28889|Crenarchaeota 28889|Crenarchaeota L Reverse transcriptase-like rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RVT_3 k59_96345_3 411473.RUMCAL_00178 6.97e-08 62.0 COG3378@1|root,COG4983@1|root,COG3378@2|Bacteria,COG4983@2|Bacteria,1TQP9@1239|Firmicutes,24AY6@186801|Clostridia,3WHX7@541000|Ruminococcaceae 186801|Clostridia S Phage plasmid primase, P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,PriCT_1,Prim-Pol k59_314111_1 948071.S4S2D9_9CAUD 1.97e-38 143.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae 10744|Podoviridae S ribonucleoside-triphosphate reductase activity - - - - - - - - - - - - - k59_21050_2 1123052.AUDF01000003_gene140 0.000155 45.4 COG0629@1|root,COG0629@2|Bacteria,2GQIQ@201174|Actinobacteria,4FPU3@85023|Microbacteriaceae 201174|Actinobacteria L Single-strand binding protein family ssb2 - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_167873_1 1121940.AUDZ01000007_gene2163 1.98e-23 95.5 2AT0I@1|root,31IGD@2|Bacteria,1NAE0@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_264803_1 103807.Q9MBZ3_9CAUD 1.44e-18 82.0 4QHC8@10239|Viruses,4QZ9A@35237|dsDNA viruses no RNA stage,4QSRC@28883|Caudovirales,4QKFD@10662|Myoviridae 10662|Myoviridae S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - - k59_189164_2 988656.F0V6Y2_9CAUD 5.18e-44 149.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNX8@10744|Podoviridae 10744|Podoviridae S N-acetylmuramoyl-L-alanine amidase activity - GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0008150,GO:0008745,GO:0016032,GO:0016787,GO:0016810,GO:0016811,GO:0019048,GO:0019058,GO:0019076,GO:0031640,GO:0032897,GO:0035821,GO:0035890,GO:0035891,GO:0039633,GO:0040011,GO:0043900,GO:0043901,GO:0043903,GO:0044003,GO:0044004,GO:0044364,GO:0044403,GO:0044419,GO:0044659,GO:0044661,GO:0046782,GO:0048519,GO:0048525,GO:0050789,GO:0050792,GO:0051701,GO:0051704,GO:0051817,GO:0051818,GO:0051883,GO:0052126,GO:0052192,GO:0061783,GO:0065007 - - - - - - - - - - - k59_229682_2 1172180.KB911804_gene1132 4.82e-82 258.0 2C8MZ@1|root,2ZA7T@2|Bacteria,2I7QK@201174|Actinobacteria 201174|Actinobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_291160_1 314275.MADE_000001022515 3.53e-31 131.0 COG0749@1|root,COG0749@2|Bacteria,1MWX7@1224|Proteobacteria,1S0Q1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L ORF located using Glimmer RBSfinder - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A,DNA_pol_A_exo1 k59_204630_1 536019.Mesop_3364 1.77e-07 63.5 COG5301@1|root,COG5301@2|Bacteria,1QW67@1224|Proteobacteria,2UGK8@28211|Alphaproteobacteria 28211|Alphaproteobacteria G cellulose 1,4-beta-cellobiosidase activity - - - - - - - - - - - - PTR k59_144002_1 1692249.A0A0K1RL40_9CIRC 8.54e-31 120.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388513_1 1379708.S5SYC3_9CIRC 6.34e-48 165.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_388518_1 1692244.A0A0K1RLR5_9CIRC 1.12e-36 139.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388518_2 1379708.S5SYC3_9CIRC 3.92e-55 185.0 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_192475_2 1458462.JNLK01000001_gene1293 0.000121 48.1 COG3773@1|root,COG5263@1|root,COG3773@2|Bacteria,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - 3.5.1.28 ko:K01449 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - CW_binding_1,Hydrolase_2,SH3_3 k59_388536_1 1618248.A0A0C5IB82_9CIRC 1.49e-24 103.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_194231_6 312153.Pnuc_1279 1.11e-42 145.0 2AV7S@1|root,31KYE@2|Bacteria,1RKQ6@1224|Proteobacteria,2VYWQ@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_194239_2 1692258.A0A0K1RL51_9CIRC 5e-57 192.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_194339_7 1122939.ATUD01000001_gene222 0.000253 42.7 2E3V5@1|root,32JJK@2|Bacteria,2HPIX@201174|Actinobacteria,4CQWE@84995|Rubrobacteria 84995|Rubrobacteria - - - - - - - - - - - - - - - k59_73141_3 1609634.A0A0C5AFV4_9VIRU 3.92e-191 552.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_73141_4 105154.Q9MBU3_9VIRU 2.32e-08 60.1 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_133882_4 722419.PH505_bb00670 1.66e-15 87.0 COG5281@1|root,COG5283@1|root,COG5281@2|Bacteria,COG5283@2|Bacteria 2|Bacteria D sister chromatid segregation - - - - - - - - - - - - PhageMin_Tail,TMP_2,Tape_meas_lam_C k59_12332_8 1555202.A0A097EX03_9CAUD 2.27e-06 50.1 4QHMD@10239|Viruses,4QRG7@28883|Caudovirales,4QIFJ@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_12332_11 321955.AAGP01000022_gene1821 4.26e-07 58.2 COG1961@1|root,COG1961@2|Bacteria,2HSUX@201174|Actinobacteria,4FAUV@85019|Brevibacteriaceae 201174|Actinobacteria L Resolvase, N terminal domain - - - - - - - - - - - - HTH_7,Resolvase k59_12332_15 1121935.AQXX01000130_gene2460 9.89e-36 135.0 2CWYZ@1|root,32T0P@2|Bacteria,1MZEM@1224|Proteobacteria,1S9HP@1236|Gammaproteobacteria,1XPJH@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - k59_12332_17 1385935.N836_31780 3.7e-23 110.0 COG0863@1|root,COG0863@2|Bacteria,1G3H1@1117|Cyanobacteria,1H9NU@1150|Oscillatoriales 1117|Cyanobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_24954_2 1379713.S5SYD9_9CIRC 5.37e-28 109.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_24954_3 1692244.A0A0K1RLR5_9CIRC 7.45e-54 177.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_122287_2 1457393.AZ09_10555 4.45e-34 125.0 2CJW6@1|root,32SAX@2|Bacteria,1N3WF@1224|Proteobacteria,2USGV@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_340829_1 691965.D4P7D6_9CAUD 1.3e-81 264.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_207424_1 1692257.A0A0K1RL39_9CIRC 1.03e-33 132.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_207424_2 1618248.A0A0C5IB82_9CIRC 1.28e-11 64.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_304518_1 373406.Q1A0A4_9CAUD 1.57e-16 83.6 4QG9U@10239|Viruses,4R0A6@35237|dsDNA viruses no RNA stage,4QSKC@28883|Caudovirales,4QM4R@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_74208_2 1788439.A0A190WHD0_9CIRC 9.73e-35 135.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_244047_3 1217715.F994_02776 6.22e-12 66.6 2DYV8@1|root,32V63@2|Bacteria,1QNWV@1224|Proteobacteria,1ST2X@1236|Gammaproteobacteria,3NNP1@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_86204_1 1609634.A0A0C5AFT2_9VIRU 6.02e-91 277.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_1228_3 1385658.U5KPZ6_9VIRU 2.8e-208 596.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_1228_6 1385658.U5KNR1_9VIRU 2.12e-64 213.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_159246_2 1618254.A0A0C5IBG4_9CIRC 3.11e-113 333.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_281258_1 759938.F5BSB4_9CIRC 1.91e-26 112.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_62287_1 1379692.S5SXY7_9CIRC 1.27e-17 92.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_37762_1 1027273.GZ77_21170 4.6e-13 74.3 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1MVH7@1224|Proteobacteria,1S09Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria KL Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_256477_1 1788439.A0A190WHD0_9CIRC 3.81e-23 106.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_122963_1 1618256.A0A0C5IM93_9CIRC 6.16e-27 110.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_171368_3 1609634.A0A0C5ANA6_9VIRU 1.23e-21 95.9 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_171368_5 1041826.FCOL_05440 1.43e-42 150.0 COG0270@1|root,COG0270@2|Bacteria,4P351@976|Bacteroidetes,1I9UJ@117743|Flavobacteriia,2NZ0G@237|Flavobacterium 976|Bacteroidetes L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_171368_7 1609634.A0A0C5AFT2_9VIRU 1.95e-130 380.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_171368_9 1609634.A0A0C5AFV4_9VIRU 1.91e-155 456.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_74343_1 1986029.Q9MBM8_9VIRU 2.7e-101 314.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_74343_4 1986029.Q9MBM3_9VIRU 5.21e-58 194.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_209327_3 1498011.A0A096XUT1_9CAUD 1.16e-35 129.0 4QC50@10239|Viruses,4QS0Z@28883|Caudovirales,4QNPK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_172519_2 1541883.A0A088FRT0_9CAUD 7.42e-51 187.0 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales,4QJPJ@10662|Myoviridae 10662|Myoviridae S N-acetylmuramoyl-L-alanine amidase activity - GO:0005575,GO:0019012 - - - - - - - - - - - k59_51013_1 2003327.CAPSD_BPCHP 2.94e-80 267.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_196936_5 1502724.FF80_03299 6.18e-36 130.0 COG0175@1|root,COG0175@2|Bacteria 2|Bacteria EH sulfate reduction - - - - - - - - - - - - PAPS_reduct k59_282661_1 1126627.BAWE01000004_gene4279 2.52e-58 202.0 2DUMH@1|root,33R9V@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_63420_4 145579.REP_BPPHM 2.71e-12 73.9 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_63420_5 1234888.K0A2J2_9VIRU 1.46e-165 484.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_269647_3 1122919.KB905549_gene2068 1.35e-07 55.1 COG0451@1|root,COG0451@2|Bacteria,1TS59@1239|Firmicutes,4HAY0@91061|Bacilli,26T47@186822|Paenibacillaceae 91061|Bacilli M Male sterility protein arnA - 4.1.1.35,4.2.1.46,5.1.3.2 ko:K01710,ko:K01784,ko:K08678 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 M00361,M00362,M00632,M00793 R00291,R01384,R02984,R06513 RC00289,RC00402,RC00508 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd k59_99644_1 1609634.A0A0C5AFT2_9VIRU 3.61e-37 138.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_221538_1 1463921.JODF01000003_gene2354 7.08e-11 63.9 COG4695@1|root,COG4695@2|Bacteria,2GZFX@201174|Actinobacteria 201174|Actinobacteria S Phage portal protein - - - - - - - - - - - - Phage_portal k59_136120_2 285514.JNWO01000076_gene385 8.96e-05 46.2 2CDQ7@1|root,2Z7KV@2|Bacteria,2IDCC@201174|Actinobacteria 201174|Actinobacteria S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_112479_2 252305.OB2597_04555 4.18e-06 52.0 2CN1W@1|root,32SG3@2|Bacteria,1N0IV@1224|Proteobacteria,2UC9F@28211|Alphaproteobacteria,2PEN7@252301|Oceanicola 28211|Alphaproteobacteria S Phage tail tube protein, GTA-gp10 - - - - - - - - - - - - Phage_TAC_11 k59_112479_8 864051.BurJ1DRAFT_1774 0.000264 49.3 28H5T@1|root,2Z7IB@2|Bacteria,1N7V9@1224|Proteobacteria,2VJZB@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_112479_9 649638.Trad_1617 1.35e-10 65.5 2E5T9@1|root,330HK@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Sulfotransfer_2 k59_112479_10 1370125.AUWT01000052_gene4917 4.83e-10 64.3 COG4122@1|root,COG4122@2|Bacteria,2HU21@201174|Actinobacteria,238TN@1762|Mycobacteriaceae 201174|Actinobacteria S Methyltransferase domain - - - - - - - - - - - - Methyltransf_24 k59_3463_1 391619.PGA1_c18650 7.69e-18 77.4 2EF8R@1|root,32W7B@2|Bacteria,1N6JW@1224|Proteobacteria,2UTFX@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_246027_1 145579.H_BPPHM 3.05e-07 55.5 4QCA6@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_148927_2 375286.mma_2226 2.36e-08 56.6 2C9JF@1|root,32RPD@2|Bacteria,1N8CG@1224|Proteobacteria,2VXEV@28216|Betaproteobacteria 28216|Betaproteobacteria S ERF superfamily - - - - - - - - - - - - ERF k59_197681_1 1609634.A0A0C5AFT2_9VIRU 4.3e-64 206.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_161347_4 1385658.U5KNR1_9VIRU 8.52e-61 202.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_39345_1 1609634.A0A0C5AFV4_9VIRU 8.2e-69 224.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_39345_3 1609634.A0A0C5AFT2_9VIRU 4.78e-76 241.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_222443_1 913970.F8RW84_9VIRU 5.93e-07 52.8 4QCVK@10239|Viruses,4QUMV@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_149066_3 1692250.A0A0K1RLR1_9CIRC 9.46e-75 235.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_136838_2 1692244.A0A0K1RLR5_9CIRC 1.36e-40 149.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_125204_1 1166948.JPZL01000002_gene1853 3.53e-07 57.4 28W3B@1|root,2ZI47@2|Bacteria,1P68T@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_39492_3 1234888.K0A2J2_9VIRU 2.2e-42 154.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_367557_1 1618248.A0A0C5IB82_9CIRC 2.36e-54 183.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_367557_3 1618248.A0A0C5IB82_9CIRC 6.66e-27 106.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_332460_2 1692247.A0A0K1RL30_9CIRC 9.12e-16 83.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_271338_1 1165094.RINTHH_3920 8.14e-62 200.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_40266_1 1968.JOEV01000056_gene4918 2.75e-50 177.0 2EYX9@1|root,33S42@2|Bacteria,2IABS@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - Phage_capsid k59_15415_3 1537917.JU82_09980 2.66e-25 99.8 2ARVA@1|root,31H70@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - HK97-gp10_like k59_320587_1 988656.F0V6Z9_9CAUD 7.44e-05 45.1 4QBMX@10239|Viruses,4QV9I@35237|dsDNA viruses no RNA stage,4QQGF@28883|Caudovirales,4QNC1@10744|Podoviridae 10744|Podoviridae S Pfam:Tube - GO:0005575,GO:0019012 - - - - - - - - - - - k59_320587_2 1220601.L7TJ83_9CAUD 2.08e-61 201.0 4QHD0@10239|Viruses,4QXZW@35237|dsDNA viruses no RNA stage,4QUGC@28883|Caudovirales 28883|Caudovirales S T=7 icosahedral viral capsid - GO:0003674,GO:0005488,GO:0005515,GO:0042802 - - - - - - - - - - - k59_356686_2 1283079.M1IDW1_9CAUD 9.57e-40 136.0 4QASP@10239|Viruses,4QVR8@35237|dsDNA viruses no RNA stage,4QR4Z@28883|Caudovirales,4QNQ0@10744|Podoviridae 10744|Podoviridae S deoxyribonuclease IV (phage-T4-induced) activity - - - - - - - - - - - - - k59_344523_1 1204526.K4I341_9CAUD 9.9e-10 59.7 4QAY9@10239|Viruses,4QV7W@35237|dsDNA viruses no RNA stage,4QPAN@28883|Caudovirales,4QKV1@10699|Siphoviridae 10699|Siphoviridae S hydrolase activity - - - - - - - - - - - - - k59_126113_1 551790.B5BTV3_9CAUD 7.12e-18 90.1 4QAWG@10239|Viruses,4QZ9F@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_28808_2 1004149.AFOE01000018_gene574 5.77e-06 55.5 COG3291@1|root,COG4412@1|root,COG4733@1|root,COG5644@1|root,COG3291@2|Bacteria,COG4412@2|Bacteria,COG4733@2|Bacteria,COG5644@2|Bacteria,4P2UU@976|Bacteroidetes,1HYAX@117743|Flavobacteriia 976|Bacteroidetes DZ TIGRFAM Bacterial surface protein 26-residue repeat - - - - - - - - - - - - CHU_C,Cadherin,DUF285,TIG,TSP_3 k59_295987_1 1105367.CG50_10630 1.48e-11 74.7 COG2911@1|root,COG5281@1|root,COG5283@1|root,COG2911@2|Bacteria,COG5281@2|Bacteria,COG5283@2|Bacteria,1QU6S@1224|Proteobacteria,2TXGV@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Lambda phage tail tape-measure protein (Tape_meas_lam_C) - - - - - - - - - - - - Tape_meas_lam_C k59_101698_2 563192.HMPREF0179_00147 3.98e-11 65.9 28JXH@1|root,2ZA3Z@2|Bacteria,1R8CZ@1224|Proteobacteria,42WKC@68525|delta/epsilon subdivisions,2WUAM@28221|Deltaproteobacteria,2MEKQ@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_296968_5 948071.S4S2D9_9CAUD 7.86e-231 657.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae 10744|Podoviridae S ribonucleoside-triphosphate reductase activity - - - - - - - - - - - - - k59_163401_1 1379719.S5TMX6_9CIRC 5.94e-22 98.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_260117_1 1234888.K0A2J2_9VIRU 1.13e-58 199.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_151079_3 1551642.A0A097BXN7_9CAUD 9.65e-56 193.0 4QAKM@10239|Viruses,4QPEF@28883|Caudovirales,4QKNE@10699|Siphoviridae 10699|Siphoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k59_139087_5 1345697.M493_16385 0.000765 48.5 COG0265@1|root,COG4632@1|root,COG0265@2|Bacteria,COG4632@2|Bacteria,1UW1X@1239|Firmicutes,4I2D9@91061|Bacilli,1WHKS@129337|Geobacillus 91061|Bacilli G PFAM S-layer homology region - - - - - - - - - - - - SLH k59_369506_5 1234888.K0A2J2_9VIRU 2.43e-147 437.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_345687_1 105154.Q9MBU0_9VIRU 1.02e-34 131.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_345687_2 105154.Q9MBU2_9VIRU 8.25e-20 87.4 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_78374_1 1380394.JADL01000006_gene5258 6.18e-52 176.0 28NGF@1|root,2ZBII@2|Bacteria,1R9KY@1224|Proteobacteria,2U1P7@28211|Alphaproteobacteria,2JXPF@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_30087_1 1618237.A0A0C5IMG6_9CIRC 1.61e-12 72.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_297210_2 2003327.CAPSD_BPCHP 9.93e-35 136.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_66429_2 571166.KI421509_gene1199 6.49e-09 63.5 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,2TUXC@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Type III restriction enzyme res subunit - - - ko:K19789 - - - - ko00000,ko03400 - - - DUF3427,HIT,Helicase_C,PLDc_2,ResIII,UPF0547 k59_310263_1 691965.D4P7I3_9CAUD 1.7e-105 345.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_213641_1 1003195.SCAT_0615 8.67e-91 276.0 28MC2@1|root,2ZAQD@2|Bacteria,2IKMZ@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_200772_1 1472912.A0A023NH00_9CAUD 1.98e-63 205.0 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QPEB@28883|Caudovirales 28883|Caudovirales S phosphoprotein phosphatase activity - - - - - - - - - - - - - k59_310269_3 340099.Teth39_1339 5.76e-09 57.0 COG3409@1|root,COG3409@2|Bacteria,1VDWB@1239|Firmicutes,24P7Z@186801|Clostridia,42H0E@68295|Thermoanaerobacterales 186801|Clostridia M PFAM Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - PG_binding_1 k59_115286_2 1510531.JQJJ01000013_gene47 1.47e-13 73.6 COG0500@1|root,COG2226@2|Bacteria,1N73D@1224|Proteobacteria,2U7VH@28211|Alphaproteobacteria,3K61C@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 k59_115286_4 247639.MGP2080_05417 1.94e-36 130.0 COG4627@1|root,COG4627@2|Bacteria,1N2HA@1224|Proteobacteria,1SJB1@1236|Gammaproteobacteria 1236|Gammaproteobacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Methyltransf_11 k59_115286_5 1297569.MESS2_1220034 6.99e-66 211.0 COG1442@1|root,COG1442@2|Bacteria,1QH4S@1224|Proteobacteria,2U9KQ@28211|Alphaproteobacteria,43JIY@69277|Phyllobacteriaceae 28211|Alphaproteobacteria M glycosyl transferase family 8 - - - - - - - - - - - - - k59_115286_6 1147150.K7PM60_9CAUD 1.94e-46 157.0 4QB1F@10239|Viruses,4QUYH@35237|dsDNA viruses no RNA stage,4QPSW@28883|Caudovirales,4QKPW@10699|Siphoviridae 10699|Siphoviridae S exonuclease activity - - - - - - - - - - - - - k59_115286_7 443152.MDG893_20584 1.09e-42 143.0 2DM6W@1|root,32UGB@2|Bacteria,1N425@1224|Proteobacteria,1SB1W@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3168) - - - - - - - - - - - - DUF3168 k59_115286_8 1437882.AZRU01000008_gene2966 9.58e-45 151.0 2DNA4@1|root,32WDI@2|Bacteria,1RH8K@1224|Proteobacteria,1S8YN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage tail tube, TTP, lambda-like - - - - - - - - - - - - Phage_TTP_11 k59_115286_9 1123020.AUIE01000007_gene3223 8.11e-35 124.0 2CHRA@1|root,32S6D@2|Bacteria,1MZ8I@1224|Proteobacteria,1SHSQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage tail assembly chaperone, TAC - - - - - - - - - - - - Phage_TAC_13 k59_115286_11 351746.Pput_4103 3.19e-24 117.0 COG2911@1|root,COG5281@1|root,COG2911@2|Bacteria,COG5281@2|Bacteria,1QU6S@1224|Proteobacteria,1S7WY@1236|Gammaproteobacteria 1236|Gammaproteobacteria D tail tape measure protein - - - - - - - - - - - - SLT,Tape_meas_lam_C k59_115286_12 1397284.AYMN01000049_gene967 7.73e-05 53.1 28P1G@1|root,2ZBXT@2|Bacteria,1QX9M@1224|Proteobacteria,1S177@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_115286_13 1548905.A0A0A1IX16_9CAUD 1.87e-74 235.0 4QBTT@10239|Viruses,4QQUU@28883|Caudovirales,4QKWB@10699|Siphoviridae 10699|Siphoviridae S Phage conserved hypothetical protein BR0599 - - - - - - - - - - - - - k59_115286_14 335283.Neut_1457 3.49e-22 88.2 2CJX7@1|root,32W32@2|Bacteria,1N82M@1224|Proteobacteria,2VY34@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_115286_15 202954.BBNK01000004_gene2057 1.14e-13 65.9 2BM2S@1|root,32FJW@2|Bacteria,1Q0N0@1224|Proteobacteria,1T788@1236|Gammaproteobacteria,3NS9E@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_115286_16 335283.Neut_1455 3.21e-117 397.0 COG2304@1|root,COG4733@1|root,COG2304@2|Bacteria,COG4733@2|Bacteria,1MXB4@1224|Proteobacteria,2VJS7@28216|Betaproteobacteria 28216|Betaproteobacteria M Putative phage tail protein - - - - - - - - - - - - Phage-tail_3 k59_115286_20 585.DR95_513 1.99e-62 207.0 28JXH@1|root,2Z9MZ@2|Bacteria,1MXNC@1224|Proteobacteria,1RNI6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S RecT family STY2074 - - - - - - - - - - - RecT k59_115286_21 1120963.KB894511_gene2520 2.82e-62 206.0 COG5377@1|root,COG5377@2|Bacteria,1MWP8@1224|Proteobacteria,1RN9Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria L COG5377 Phage-related protein - - - - - - - - - - - - YqaJ k59_358383_3 742740.HMPREF9474_02251 2e-15 73.9 2EK5K@1|root,33DW0@2|Bacteria,1UU54@1239|Firmicutes,255II@186801|Clostridia 186801|Clostridia S Putative phage holin Dp-1 - - - - - - - - - - - - Phage_holin_Dp1 k59_358383_4 742740.HMPREF9474_02252 3.91e-30 111.0 2BT3T@1|root,30VXX@2|Bacteria,1U239@1239|Firmicutes,25JN1@186801|Clostridia,2232Q@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_358383_6 665956.HMPREF1032_00688 6.12e-98 301.0 28K55@1|root,2Z9TX@2|Bacteria,1V0P7@1239|Firmicutes,24DCX@186801|Clostridia,3WK99@541000|Ruminococcaceae 186801|Clostridia S Psort location Cytoplasmic, score 7.50 - - - - - - - - - - - - Sipho_Gp37 k59_358383_8 742733.HMPREF9469_05020 9.79e-21 105.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,221IX@1506553|Lachnoclostridium 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_140178_8 994479.GL877878_gene3344 9.46e-19 99.8 COG3941@1|root,COG3953@1|root,COG5412@1|root,COG3941@2|Bacteria,COG3953@2|Bacteria,COG5412@2|Bacteria,2GNNQ@201174|Actinobacteria,4E86P@85010|Pseudonocardiales 201174|Actinobacteria M phage tail tape measure protein - - - - - - - - - - - - PhageMin_Tail,SLT k59_287695_1 691965.D4P7D6_9CAUD 8.98e-117 359.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_334789_1 1168281.I3PUX6_9CAUD 1.02e-29 122.0 4QCM6@10239|Viruses,4QVAQ@35237|dsDNA viruses no RNA stage,4QPVV@28883|Caudovirales,4QNID@10744|Podoviridae 10744|Podoviridae S actin binding - - - - - - - - - - - - - k59_103773_1 1327776.R4JIS0_9CAUD 2.57e-114 343.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_335594_1 1385658.U5KPZ6_9VIRU 9.66e-35 135.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_140931_2 319225.Plut_0075 4.36e-09 60.8 COG0216@1|root,COG0216@2|Bacteria,1FDJD@1090|Chlorobi 1090|Chlorobi J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 k59_347574_2 498848.TaqDRAFT_4764 6.73e-10 63.9 COG0210@1|root,COG0210@2|Bacteria,1WN9U@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L UvrD-like helicase C-terminal domain - - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k59_55802_2 1337093.MBE-LCI_1558 1.56e-13 67.4 2E6JI@1|root,3316K@2|Bacteria,1PP48@1224|Proteobacteria,2UT9Y@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_68288_3 691965.D4P7C0_9CAUD 2.18e-55 176.0 4QDUR@10239|Viruses,4QVMY@35237|dsDNA viruses no RNA stage,4QU8R@28883|Caudovirales,4QKNQ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_31835_2 1552758.NC00_01300 7.14e-50 164.0 COG4678@1|root,COG4678@2|Bacteria,1R92U@1224|Proteobacteria,1S23X@1236|Gammaproteobacteria,1X979@135614|Xanthomonadales 135614|Xanthomonadales G Phage lysozyme - - - - - - - - - - - - Phage_lysozyme k59_335608_2 460265.Mnod_6241 2.47e-08 55.1 2ABTE@1|root,3119Z@2|Bacteria,1NP1V@1224|Proteobacteria,2UKGX@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF4054) - - - - - - - - - - - - DUF4054 k59_68514_1 1122176.KB903547_gene1097 2.35e-06 56.2 COG4733@1|root,COG4733@2|Bacteria,4NPYJ@976|Bacteroidetes,1IV35@117747|Sphingobacteriia 976|Bacteroidetes S Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - Laminin_G_3 k59_32068_1 1234888.K0A2J2_9VIRU 9.04e-68 223.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_55967_1 1609634.A0A0C5AFV4_9VIRU 6.76e-104 318.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_104613_1 1545915.JROG01000004_gene1901 2e-05 53.9 2DSHN@1|root,33G5Q@2|Bacteria,1NGM3@1224|Proteobacteria,2UK0H@28211|Alphaproteobacteria,2K4KJ@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - k59_104613_2 1095743.HMPREF1054_1761 0.000879 43.5 COG1196@1|root,COG3941@1|root,COG1196@2|Bacteria,COG3941@2|Bacteria,1R19H@1224|Proteobacteria,1T4WY@1236|Gammaproteobacteria 1236|Gammaproteobacteria D Prophage tail length tape measure protein - - - - - - - - - - - - TMP_2 k59_104613_5 1049564.TevJSym_bj00150 2.79e-24 118.0 COG2982@1|root,COG3420@1|root,COG2982@2|Bacteria,COG3420@2|Bacteria,1QWWH@1224|Proteobacteria 1224|Proteobacteria P Beta-L-arabinofuranosidase, GH127 - - - - - - - - - - - - Beta_helix,NosD,W_rich_C k59_201911_1 1385658.U5KPZ6_9VIRU 9.97e-117 352.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_359431_1 1609634.A0A0C5AFV4_9VIRU 6.31e-35 136.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_274724_2 575589.HMPREF0018_00194 3.14e-13 66.2 COG2852@1|root,COG2852@2|Bacteria,1N7EJ@1224|Proteobacteria,1SF5D@1236|Gammaproteobacteria,3NP22@468|Moraxellaceae 1236|Gammaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - DUF559 k59_117045_2 865938.Weevi_0254 6.59e-19 92.0 COG1783@1|root,COG1783@2|Bacteria,4P9P0@976|Bacteroidetes,1I733@117743|Flavobacteriia 976|Bacteroidetes S Phage terminase large subunit - - - ko:K06909 - - - - ko00000 - - - Terminase_3 k59_32799_1 289377.HL41_07045 4.75e-19 88.6 COG3948@1|root,COG3948@2|Bacteria 2|Bacteria S Baseplate J-like protein - - - - - - - - - - - - Baseplate_J k59_32799_2 414684.RC1_1132 3e-28 106.0 COG3628@1|root,COG3628@2|Bacteria,1NDEW@1224|Proteobacteria,2UMA9@28211|Alphaproteobacteria,2JY1M@204441|Rhodospirillales 204441|Rhodospirillales S Gene 25-like lysozyme - - - ko:K06903 - - - - ko00000 - - - GPW_gp25 k59_56723_3 293826.Amet_2139 6.97e-07 52.8 COG3108@1|root,COG3108@2|Bacteria,1VFRJ@1239|Firmicutes,24R9N@186801|Clostridia,36TIF@31979|Clostridiaceae 186801|Clostridia S Peptidase M15A - - 3.4.17.14 ko:K08640 - - - - ko00000,ko01000,ko01002,ko01011 - - - PG_binding_1,Peptidase_M15_3 k59_359975_1 269797.Mbar_A2783 0.000313 53.5 COG3291@1|root,arCOG02515@1|root,arCOG02527@1|root,arCOG02510@2157|Archaea,arCOG02515@2157|Archaea,arCOG02527@2157|Archaea,2Y7RP@28890|Euryarchaeota,2NBKZ@224756|Methanomicrobia 224756|Methanomicrobia S Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - - - - - - - - - - CARDB,DUF3344,PKD k59_372429_2 391615.ABSJ01000041_gene59 5.32e-17 88.2 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1J4YE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_178970_1 1692255.A0A0K1RL52_9CIRC 1.45e-11 68.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_238895_1 575540.Isop_3001 3.12e-06 55.1 COG4974@1|root,COG4974@2|Bacteria,2IX6A@203682|Planctomycetes 203682|Planctomycetes D Belongs to the 'phage' integrase family. XerC subfamily - - - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase k59_372432_1 1469245.JFBG01000061_gene2319 4.09e-08 59.3 COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,1S2U7@1236|Gammaproteobacteria,1WWN0@135613|Chromatiales 135613|Chromatiales L TIGRFAM Phage SPO1 DNA polymerase-related protein - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_33044_1 153948.NAL212_1093 1.67e-05 53.5 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2VJ57@28216|Betaproteobacteria,372B8@32003|Nitrosomonadales 28216|Betaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_8291_3 1123401.JHYQ01000001_gene1770 7.49e-44 147.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,460QZ@72273|Thiotrichales 72273|Thiotrichales L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_56937_2 1453501.JELR01000002_gene1496 1.83e-22 94.7 COG0330@1|root,COG0330@2|Bacteria,1MX2I@1224|Proteobacteria 1224|Proteobacteria O COG0330 Membrane protease subunits stomatin prohibitin homologs - - - - - - - - - - - - Band_7 k59_19206_1 186617.M9M8L2_9VIRU 7.72e-44 158.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_360191_1 557598.LHK_01554 4.41e-13 75.1 COG0503@1|root,COG0503@2|Bacteria 2|Bacteria F purine ribonucleoside salvage apt - 2.4.2.22,2.4.2.7 ko:K00759,ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R00190,R01229,R02142,R04378 RC00063,RC00122 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran k59_69375_1 1386969.AWTB01000003_gene2016 1.11e-23 104.0 2C9AC@1|root,2Z7TR@2|Bacteria,2I07F@201174|Actinobacteria,4GCVZ@85026|Gordoniaceae 201174|Actinobacteria S Phage portal protein, SPP1 Gp6-like - - - - - - - - - - - - Phage_prot_Gp6 k59_170294_37 637905.SVI_1978 3.64e-23 94.7 2A3Q7@1|root,30S7S@2|Bacteria,1NP2K@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_170294_55 314282.PCNPT3_11640 5.93e-22 95.1 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,2QHMK@267894|Psychromonadaceae 1236|Gammaproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363,GO:1901576 - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_170294_57 113395.AXAI01000008_gene735 4.16e-09 62.0 COG1403@1|root,COG1403@2|Bacteria,1N0FM@1224|Proteobacteria,2TWQN@28211|Alphaproteobacteria 28211|Alphaproteobacteria V ERF superfamily - - - - - - - - - - - - ERF k59_170294_66 882378.RBRH_01223 4.69e-33 131.0 2EUW1@1|root,33070@2|Bacteria,1QVAM@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_170294_67 1122164.JHWF01000028_gene690 3.37e-71 238.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1JD5F@118969|Legionellales 118969|Legionellales L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_170294_70 1196322.A370_05742 9.74e-14 71.2 2C6KN@1|root,32Y69@2|Bacteria,1VANX@1239|Firmicutes,24MNG@186801|Clostridia,36KM4@31979|Clostridiaceae 186801|Clostridia S VRR-NUC domain - - - - - - - - - - - - VRR_NUC k59_85436_1 888832.HMPREF9420_1956 6.98e-10 68.2 COG5283@1|root,COG5283@2|Bacteria,4NIZH@976|Bacteroidetes,2G14D@200643|Bacteroidia 976|Bacteroidetes D domain protein - - - - - - - - - - - - PhageMin_Tail k59_206957_6 1403819.BATR01000162_gene5299 7.58e-105 327.0 COG0305@1|root,COG0305@2|Bacteria,46SKM@74201|Verrucomicrobia,2ITGD@203494|Verrucomicrobiae 203494|Verrucomicrobiae L DnaB-like helicase C terminal domain - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_206957_8 3712.Bo3g185000.1 9.61e-10 68.2 KOG4197@1|root,KOG4197@2759|Eukaryota 2759|Eukaryota S endonuclease activity - GO:0000003,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006725,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0009451,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016070,GO:0016787,GO:0016788,GO:0022414,GO:0022622,GO:0032501,GO:0032502,GO:0034641,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0048316,GO:0048364,GO:0048367,GO:0048608,GO:0048731,GO:0048856,GO:0061458,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0099402,GO:1901360,GO:1901363 - - - - - - - - - - PPR,PPR_1,PPR_2,PPR_3 k59_49034_2 1692244.A0A0K1RLR5_9CIRC 1.85e-84 261.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_73259_2 2003327.CAPSD_BPCHP 1.35e-46 178.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_219487_2 1420600.W5RNT1_9CIRC 5.03e-35 132.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_158676_1 1692249.A0A0K1RLN8_9CIRC 9.23e-46 159.0 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_267784_2 72558.CBQ72472 2.83e-21 95.5 COG0328@1|root,KOG3752@2759|Eukaryota,39U14@33154|Opisthokonta,3NU3Q@4751|Fungi,3V16N@5204|Basidiomycota 4751|Fungi L Ribonuclease - GO:0000228,GO:0000278,GO:0000785,GO:0000790,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022402,GO:0022616,GO:0031974,GO:0031981,GO:0033260,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0044786,GO:0045005,GO:0046483,GO:0046700,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576,GO:1902298,GO:1902969,GO:1903047,GO:1990505 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - Cauli_VI,RNase_H k59_328689_2 1122614.JHZF01000011_gene1718 5.34e-16 75.9 2C7JB@1|root,2ZXVG@2|Bacteria,1P7GB@1224|Proteobacteria,2UYPK@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_328689_3 428125.CLOLEP_01415 1.01e-34 127.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia,3WNFY@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_1392_2 105154.Q9MBU6_9VIRU 1.72e-222 632.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_317432_1 1234888.K0A2J2_9VIRU 8.9e-22 95.9 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_50028_1 856793.MICA_1841 6.48e-86 265.0 28HS3@1|root,2Z7ZE@2|Bacteria,1QH9A@1224|Proteobacteria,2TVB0@28211|Alphaproteobacteria,4BR65@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_305220_3 10872.VG301_BPPF3 2.18e-45 164.0 4QBME@10239|Viruses,4QUKP@29258|ssDNA viruses,4QP4G@10860|Inoviridae 10860|Inoviridae S Zonular occludens toxin (Zot) - - - - - - - - - - - - - k59_1395_1 357276.EL88_12705 1.09e-57 198.0 COG0863@1|root,COG0863@2|Bacteria,4PMGB@976|Bacteroidetes,2G0C7@200643|Bacteroidia,4APG6@815|Bacteroidaceae 976|Bacteroidetes L Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - - k59_220334_1 1283076.M1IDC7_9CAUD 3.91e-83 285.0 4QEE7@10239|Viruses,4QV59@35237|dsDNA viruses no RNA stage,4QPT7@28883|Caudovirales,4QI2X@10662|Myoviridae 10662|Myoviridae S Pfam:DUF4815 - - - - - - - - - - - - - k59_220334_3 1283076.M1HLR4_9CAUD 1.18e-69 241.0 4QF7I@10239|Viruses,4QYCA@35237|dsDNA viruses no RNA stage,4QT9A@28883|Caudovirales,4QKJH@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_317433_1 1211844.CBLM010000090_gene2699 1.85e-16 85.1 COG0338@1|root,COG0338@2|Bacteria,1TRDX@1239|Firmicutes 1239|Firmicutes L site-specific DNA-methyltransferase (Adenine-specific) dam - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_208346_5 343509.SG1213 1.47e-15 73.2 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,1S99W@1236|Gammaproteobacteria 1236|Gammaproteobacteria G lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_123153_3 1618258.A0A0C5I9K3_9CIRC 5.15e-19 95.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_98708_2 142661.REP_CACV 3.47e-31 126.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_86504_1 1121413.JMKT01000011_gene2344 4.83e-33 120.0 2D1GK@1|root,32TAP@2|Bacteria,1QV4T@1224|Proteobacteria,43CXG@68525|delta/epsilon subdivisions,2X85J@28221|Deltaproteobacteria,2MFAA@213115|Desulfovibrionales 28221|Deltaproteobacteria L C-5 cytosine-specific DNA methylase - - - - - - - - - - - - - k59_86504_3 423476.A3F629_9CAUD 6.74e-45 155.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_50218_1 160488.PP_2266 1.15e-36 145.0 COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria,1SM2Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria K DNA-dependent RNA polymerase - - 2.7.7.6 ko:K21313 - - - - ko00000,ko01000,ko03200 - - - RNA_pol,RPOL_N k59_38662_6 546273.VEIDISOL_00724 3.58e-20 106.0 COG5281@1|root,COG5281@2|Bacteria,1TPWF@1239|Firmicutes,4H3NF@909932|Negativicutes 909932|Negativicutes S tape measure - - - - - - - - - - - - - k59_245477_1 1121904.ARBP01000066_gene2210 8.82e-09 60.1 COG1876@1|root,COG3209@1|root,COG1876@2|Bacteria,COG3209@2|Bacteria 2|Bacteria M self proteolysis cwlK - - ko:K17733 - - - - ko00000,ko01000,ko01002,ko01011 - - - Cu_amine_oxidN1,DUF2809,PG_binding_1,Peptidase_M15_4,VanY k59_283065_1 1379708.S5SYC3_9CIRC 5.7e-15 80.1 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_283065_2 1618236.A0A0C5IB23_9CIRC 7.67e-40 150.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_318967_3 870187.Thini_0411 5.23e-22 100.0 2EP1Y@1|root,33GNT@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_99847_1 1197951.I6R0Y7_9CAUD 8.35e-26 109.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales 28883|Caudovirales S DnaB-like helicase C terminal domain - - - - - - - - - - - - - k59_99847_2 938288.HG326226_gene780 1.29e-20 89.7 COG1351@1|root,COG1351@2|Bacteria,1TRHD@1239|Firmicutes,24AQH@186801|Clostridia 186801|Clostridia F Thymidylate synthase complementing protein - - - - - - - - - - - - Thy1 k59_379334_1 716928.AJQT01000109_gene1217 6.93e-33 119.0 2FEUE@1|root,346TC@2|Bacteria,1MZPB@1224|Proteobacteria,2UC4Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_2805_1 1788447.A0A190WHJ9_9CIRC 8.14e-09 62.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_283068_2 374847.Kcr_0594 0.00038 50.4 COG1633@1|root,arCOG05908@2157|Archaea 2157|Archaea S PFAM Encapsulating protein for peroxidase - - - - - - - - - - - - Linocin_M18,Rubrerythrin k59_148308_2 324602.Caur_1511 1.36e-09 63.2 COG2227@1|root,COG2227@2|Bacteria 2|Bacteria H 3-demethylubiquinone-9 3-O-methyltransferase activity - - - ko:K06219 - - - - ko00000 - - - Methyltransf_11,Methyltransf_23,Methyltransf_25 k59_27059_2 1420600.W5RNT1_9CIRC 4.04e-16 85.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_355100_3 1217710.F969_00036 2.44e-89 287.0 COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,1RY0J@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_38861_1 57119.REP_BEYDV 7.15e-12 68.6 4QB6C@10239|Viruses,4QUKM@29258|ssDNA viruses 10239|Viruses J Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_148310_1 1618236.A0A0C5I2F3_9CIRC 1.45e-31 125.0 4QGVY@10239|Viruses,4QUKN@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_89109_1 1788452.A0A190WHG0_9CIRC 8.03e-53 181.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_113141_1 691965.D4P7D6_9CAUD 2.04e-58 204.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_271109_2 1121028.ARQE01000021_gene2539 1.78e-09 68.9 COG3325@1|root,COG3325@2|Bacteria,1RKP7@1224|Proteobacteria,2UBB4@28211|Alphaproteobacteria 28211|Alphaproteobacteria G nuclear chromosome segregation - - - - - - - - - - - - - k59_307876_2 270673.Q6PVM5_9CAUD 1.13e-14 71.6 4QGQX@10239|Viruses,4QQ2D@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_295663_3 526227.Mesil_1197 6.86e-07 55.8 COG1783@1|root,COG1783@2|Bacteria 2|Bacteria S DNA packaging - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_64991_1 1609634.A0A0C5AFV4_9VIRU 1.95e-106 330.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_89113_4 1343740.M271_23255 3.19e-06 53.1 28NEI@1|root,312GG@2|Bacteria,2GYW8@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_125771_1 89187.ISM_08070 1.05e-45 156.0 28PMA@1|root,2ZCAD@2|Bacteria,1RARQ@1224|Proteobacteria,2U6X3@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_125771_2 1408418.JNJH01000015_gene3301 4.06e-22 99.0 COG0863@1|root,COG0863@2|Bacteria,1R7RR@1224|Proteobacteria,2TS8Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - - - - - - - - - - - N6_N4_Mtase k59_40074_1 279280.Q6J1R6_9CAUD 3.38e-20 90.5 4QBMX@10239|Viruses,4QV9I@35237|dsDNA viruses no RNA stage,4QQGF@28883|Caudovirales,4QNC1@10744|Podoviridae 10744|Podoviridae S Pfam:Tube - GO:0005575,GO:0019012 - - - - - - - - - - - k59_113142_2 1122201.AUAZ01000017_gene2960 8.11e-219 619.0 COG5362@1|root,COG5362@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Terminase_6C k59_210997_2 105154.Q9MBU3_9VIRU 2.77e-07 56.6 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_198444_3 1385658.U5KPZ6_9VIRU 2.61e-06 50.4 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_380760_1 1476888.X4Y7Y5_9CAUD 0.000107 43.5 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_380760_2 411460.RUMTOR_01348 1.45e-95 294.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_52732_2 1357714.A0A067XQP4_9CAUD 1.21e-27 112.0 4QAX9@10239|Viruses,4QVNY@35237|dsDNA viruses no RNA stage,4QPQH@28883|Caudovirales,4QHWN@10662|Myoviridae 10662|Myoviridae S T4 bacteriophage base plate protein - - - - - - - - - - - - - k59_356459_3 1121334.KB911068_gene2299 6.14e-05 55.5 COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia,3WJR8@541000|Ruminococcaceae 186801|Clostridia D Phage tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail k59_28435_1 1788454.A0A190WHE4_9CIRC 4.16e-20 89.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_295784_1 1205680.CAKO01000035_gene155 1.12e-47 171.0 COG0305@1|root,COG0305@2|Bacteria,1QT50@1224|Proteobacteria,2TTND@28211|Alphaproteobacteria,2JV0Y@204441|Rhodospirillales 204441|Rhodospirillales L AAA domain - - - - - - - - - - - - Toprim_4 k59_16523_3 1556290.A0A0A0RQH0_9CAUD 0.000311 46.6 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_199752_1 1123499.KB908020_gene867 1.34e-10 66.2 2DKZC@1|root,30ZS6@2|Bacteria,1RGQ9@1224|Proteobacteria,2W58R@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_199752_2 1110502.TMO_0053 2.14e-67 229.0 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,2TT3N@28211|Alphaproteobacteria,2JQ8P@204441|Rhodospirillales 204441|Rhodospirillales S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_30229_2 1609634.A0A0C5ANA6_9VIRU 4.98e-14 74.3 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_30229_3 1385658.U5KPZ6_9VIRU 1.13e-187 541.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_185953_1 1795993.A0A140CTQ1_9CIRC 3.63e-32 121.0 4QB6C@10239|Viruses,4QUKM@29258|ssDNA viruses 10239|Viruses J Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_272900_3 691965.D4P7H8_9CAUD 5.96e-36 132.0 4QG1E@10239|Viruses,4QZE1@35237|dsDNA viruses no RNA stage,4QU6Q@28883|Caudovirales,4QMKH@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_369670_3 1234888.K0A2J2_9VIRU 5.96e-71 234.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_114623_2 1121459.AQXE01000001_gene2774 7.24e-37 145.0 COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria,42YXG@68525|delta/epsilon subdivisions,2WU1V@28221|Deltaproteobacteria,2M9ED@213115|Desulfovibrionales 28221|Deltaproteobacteria K DNA-dependent RNA polymerase - - - - - - - - - - - - RNA_pol,RPOL_N k59_66568_3 794903.OPIT5_05420 3.75e-08 53.9 COG0451@1|root,COG0451@2|Bacteria,46UCR@74201|Verrucomicrobia 74201|Verrucomicrobia M NmrA-like family - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase k59_16720_1 105154.Q9MBU6_9VIRU 6.99e-124 375.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_102934_3 1249627.D779_1209 7.54e-27 109.0 COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,1S2U7@1236|Gammaproteobacteria,1WWN0@135613|Chromatiales 135613|Chromatiales L TIGRFAM Phage SPO1 DNA polymerase-related protein - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_321863_1 1449069.JMLO01000006_gene990 1.62e-20 95.1 COG4626@1|root,COG4626@2|Bacteria,2GM6F@201174|Actinobacteria,4FYPE@85025|Nocardiaceae 201174|Actinobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_382069_6 543728.Vapar_4333 3.21e-33 128.0 COG0457@1|root,COG0457@2|Bacteria,1RFZN@1224|Proteobacteria,2W0K5@28216|Betaproteobacteria 28216|Betaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - k59_382069_22 356851.JOAN01000003_gene1439 1.71e-08 67.0 COG5412@1|root,COG5412@2|Bacteria,2GQ9P@201174|Actinobacteria,4DFCQ@85008|Micromonosporales 201174|Actinobacteria S phage tail tape measure protein - - - - - - - - - - - - - k59_224705_3 1120965.AUBV01000009_gene3100 5.2e-22 99.8 COG4122@1|root,COG4122@2|Bacteria 2|Bacteria E O-methyltransferase activity - - - - - - - - - - - - Methyltransf_21,SAM_MT k59_201426_1 1121447.JONL01000012_gene3405 1.11e-28 119.0 COG0503@1|root,COG2518@1|root,COG0503@2|Bacteria,COG2518@2|Bacteria 2|Bacteria O Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins apt - 2.1.1.163,2.1.1.201,2.1.1.77,2.4.2.7 ko:K00573,ko:K00759,ko:K03183,ko:K07003 ko00130,ko00230,ko01100,ko01110,map00130,map00230,map01100,map01110 M00116,M00117 R00190,R01229,R04378,R04990,R04993,R06859,R08774,R09736 RC00003,RC00063,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000,ko04147 - - - DUF3560,Methyltransf_21,Pribosyltran k59_214375_1 1161401.ASJA01000008_gene1655 2.21e-46 169.0 COG3567@1|root,COG3567@2|Bacteria,1QNPU@1224|Proteobacteria,2U19C@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM phage-associated protein, HI1409 family - - - ko:K09961 - - - - ko00000 - - - DUF1073 k59_226324_3 1391455.U5XJI9_9VIRU 1.81e-18 86.3 4QEWY@10239|Viruses,4QYU5@35237|dsDNA viruses no RNA stage 10239|Viruses S Pfam:DUF5131 - - - - - - - - - - - - - k59_347354_2 1197906.CAJQ02000023_gene2191 1.14e-07 57.4 COG0673@1|root,COG0673@2|Bacteria,1Q561@1224|Proteobacteria,2UPH1@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA k59_18012_1 1234888.K0A2J2_9VIRU 2.85e-58 197.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_299093_3 1986029.Q9MBM3_9VIRU 5.16e-50 173.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_250011_2 1072685.IX83_07070 1.96e-15 79.0 2DZ82@1|root,32V6V@2|Bacteria,1N3UK@1224|Proteobacteria,2VY68@28216|Betaproteobacteria,3T7VI@506|Alcaligenaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_250263_1 1556290.A0A0A0RQP8_9CAUD 1.33e-55 198.0 4QBG4@10239|Viruses,4QRSK@28883|Caudovirales,4QKVU@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_335687_1 1692249.A0A0K1RLN8_9CIRC 1.2e-13 73.9 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_165317_1 2003327.CAPSD_BPCHP 5.66e-10 65.9 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_335690_2 1484158.PSNIH1_00390 4.91e-09 58.5 2BMAA@1|root,32FU7@2|Bacteria,1Q0QX@1224|Proteobacteria,1TE0I@1236|Gammaproteobacteria,3W2IF@53335|Pantoea 1236|Gammaproteobacteria S HNH endonuclease - - - - - - - - - - - - HNH_3 k59_360441_4 886293.Sinac_4765 2.12e-07 65.5 COG3210@1|root,COG4733@1|root,COG3210@2|Bacteria,COG4733@2|Bacteria,2J50K@203682|Planctomycetes 203682|Planctomycetes U Pkd domain containing protein - - 2.7.11.1 ko:K12567 ko05410,ko05414,map05410,map05414 - - - ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812 - - - - k59_337190_2 1609634.A0A0C5ANA6_9VIRU 3.64e-17 81.3 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_117617_1 1692249.A0A0K1RL40_9CIRC 1.15e-46 159.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_349174_1 186617.M9M8L2_9VIRU 1.67e-58 197.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_337192_1 642492.Clole_0946 7.26e-18 86.3 COG3935@1|root,COG3935@2|Bacteria,1W6YJ@1239|Firmicutes,24P7D@186801|Clostridia 186801|Clostridia L DnaD domain protein - - - - - - - - - - - - - k59_325148_1 1385658.U5KNR1_9VIRU 8.28e-07 52.4 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_325148_3 1385658.U5KPZ6_9VIRU 3.41e-173 506.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_301232_1 1522072.IL54_3330 6.12e-06 54.7 COG0010@1|root,COG0010@2|Bacteria 2|Bacteria E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines - - 3.5.3.11 ko:K01480 ko00330,ko01100,map00330,map01100 M00133 R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase k59_81944_1 1385658.U5KNR1_9VIRU 1.11e-47 166.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_179598_3 105154.Q9MBU6_9VIRU 1.98e-76 248.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_337471_1 1522072.IL54_3178 1.56e-36 132.0 COG2369@1|root,COG2369@2|Bacteria,1RFUM@1224|Proteobacteria,2UIAH@28211|Alphaproteobacteria,2KA1F@204457|Sphingomonadales 204457|Sphingomonadales S Phage Mu protein F like protein - - - - - - - - - - - - Phage_Mu_F k59_337471_2 592026.GCWU0000282_002696 1.73e-07 55.1 COG0653@1|root,COG0653@2|Bacteria,1TRHV@1239|Firmicutes,24C3T@186801|Clostridia 186801|Clostridia U SEC-C motif - - - - - - - - - - - - SEC-C k59_57487_1 279238.Saro_0377 1.29e-59 213.0 COG0553@1|root,COG0553@2|Bacteria,1MXQH@1224|Proteobacteria,2TR5V@28211|Alphaproteobacteria,2K08X@204457|Sphingomonadales 204457|Sphingomonadales KL methylase - - - - - - - - - - - - AAA_34,Helicase_C_4 k59_179599_2 742740.HMPREF9474_02272 1.87e-88 277.0 COG4626@1|root,COG4626@2|Bacteria,1TT9I@1239|Firmicutes,24AFK@186801|Clostridia,222GA@1506553|Lachnoclostridium 186801|Clostridia S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_325394_3 1609634.A0A0C5AFT2_9VIRU 9.62e-141 408.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_45279_1 357804.Ping_1595 8.77e-39 141.0 2CWXD@1|root,32T0J@2|Bacteria,1N3Z7@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_94848_1 2003327.CAPSD_BPCHP 2.13e-11 69.7 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_205223_1 396014.BF93_01780 5.23e-15 80.5 COG4942@1|root,COG4942@2|Bacteria,2I64D@201174|Actinobacteria,4FC6E@85020|Dermabacteraceae 201174|Actinobacteria D Peptidase family M23 - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 k59_339390_1 232346.JHQL01000009_gene2032 1.77e-76 251.0 2D784@1|root,32TNH@2|Bacteria,1N098@1224|Proteobacteria,1SDM3@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_119645_1 1397278.AYMV01000020_gene628 1.11e-06 50.8 COG2189@1|root,COG2189@2|Bacteria,2I8FH@201174|Actinobacteria,4FKE3@85023|Microbacteriaceae 201174|Actinobacteria L DNA methylase xbaIM - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_303192_3 1088868.CIN_21470 2.71e-68 224.0 COG0270@1|root,COG0270@2|Bacteria,1NPQG@1224|Proteobacteria,2U226@28211|Alphaproteobacteria 28211|Alphaproteobacteria L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_362443_3 351348.Maqu_1515 0.000258 53.9 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1R97W@1224|Proteobacteria,1RTIA@1236|Gammaproteobacteria,469KR@72275|Alteromonadaceae 1236|Gammaproteobacteria D Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_71821_1 1609634.A0A0C5ANA6_9VIRU 4.16e-15 78.2 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_97034_1 105154.Q9MBU0_9VIRU 9.15e-36 134.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_218582_1 1417296.U879_13400 1.98e-05 48.1 2E46I@1|root,332Q5@2|Bacteria,1NFBY@1224|Proteobacteria,2UFWQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_21847_1 2003327.CAPSD_BPCHP 7.98e-21 99.8 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_181675_3 187303.BN69_2086 1.32e-34 130.0 COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2TT5T@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB - 4.2.1.46,4.2.1.76,5.1.3.2 ko:K01710,ko:K01784,ko:K12450 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 M00361,M00362,M00632,M00793 R00291,R00293,R02984,R06513 RC00289,RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd k59_339547_1 1211777.BN77_4166 2.99e-134 407.0 COG3170@1|root,COG3170@2|Bacteria,1QVEE@1224|Proteobacteria,2TWDG@28211|Alphaproteobacteria,4BHSG@82115|Rhizobiaceae 28211|Alphaproteobacteria NU Phage P22-like portal protein - - - - - - - - - - - - P22_portal k59_35760_1 246197.MXAN_4416 2.76e-32 121.0 COG3510@1|root,COG3510@2|Bacteria,1MWJ8@1224|Proteobacteria,42M7W@68525|delta/epsilon subdivisions,2WK34@28221|Deltaproteobacteria 28221|Deltaproteobacteria V cephalosporin hydroxylase - - - - - - - - - - - - CmcI k59_388375_2 1234888.K0A2R8_9VIRU 1.39e-43 157.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_388375_3 2003327.CAPSD_BPCHP 2.06e-52 194.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_364422_3 1379722.S5SY31_9CIRC 6.7e-48 163.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388376_2 1618247.A0A0C5I2K0_9CIRC 7.07e-14 76.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_24134_1 2003327.CAPSD_BPCHP 1.3e-50 179.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_193403_1 1232410.KI421417_gene2761 1.4e-17 90.9 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1R97W@1224|Proteobacteria 1224|Proteobacteria D Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_193409_1 2003327.CAPSD_BPCHP 1.62e-09 64.7 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_193432_1 243233.MCA1515 1.35e-23 102.0 COG0438@1|root,COG4627@1|root,COG0438@2|Bacteria,COG4627@2|Bacteria,1N2HA@1224|Proteobacteria,1SJB1@1236|Gammaproteobacteria 1236|Gammaproteobacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Methyltransf_11 k59_193613_1 1429904.V5R9U2_9CAUD 9.63e-63 203.0 4QFVK@10239|Viruses,4QSUR@28883|Caudovirales,4QM8N@10699|Siphoviridae 10699|Siphoviridae S transferase activity - - - - - - - - - - - - - k59_193645_1 115711.CP_0543 1.31e-07 56.2 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_193660_1 1234888.K0A2J2_9VIRU 2.5e-13 70.1 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_193665_1 1234888.K0A2J2_9VIRU 7.2e-75 244.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_193689_1 1443113.LC20_01730 0.000179 48.9 COG1484@1|root,COG1484@2|Bacteria,1MZNW@1224|Proteobacteria,1RQFW@1236|Gammaproteobacteria,41HD1@629|Yersinia 1236|Gammaproteobacteria L IstB-like ATP binding protein dnaC - - ko:K02315 - - - - ko00000,ko03032 - - - IstB_IS21 k59_193769_1 1111732.AZOD01000009_gene1166 4.09e-73 243.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,1X48F@135614|Xanthomonadales 135614|Xanthomonadales F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN k59_193798_8 1122135.KB893141_gene84 1.11e-22 94.7 COG2131@1|root,COG2131@2|Bacteria,1RD1P@1224|Proteobacteria,2UD7X@28211|Alphaproteobacteria 28211|Alphaproteobacteria F COG2131 Deoxycytidylate deaminase - - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_377057_14 1120971.AUCA01000037_gene2881 7.12e-15 72.4 2DP7B@1|root,330UW@2|Bacteria,1VMUH@1239|Firmicutes,4I26A@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF4406) - - - - - - - - - - - - DUF4406 k59_377057_17 1545915.JROG01000003_gene1027 2.41e-30 137.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,2K1KW@204457|Sphingomonadales 204457|Sphingomonadales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_377057_18 1120980.JQKH01000093_gene1747 1.38e-88 284.0 COG2268@1|root,COG2268@2|Bacteria,1P39U@1224|Proteobacteria,2VMEW@28216|Betaproteobacteria,2KSU8@206351|Neisseriales 206351|Neisseriales S prohibitin homologues - - - - - - - - - - - - Band_7 k59_377057_20 859653.HIMB5_00002850 6.83e-27 116.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2TSF9@28211|Alphaproteobacteria,4BPP7@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_328483_2 1788439.A0A190WHD0_9CIRC 5.49e-27 111.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_24700_1 942165.E9KIG9_9CAUD 3.31e-41 156.0 4QASG@10239|Viruses,4QZZU@35237|dsDNA viruses no RNA stage,4QT37@28883|Caudovirales,4QNXD@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_133972_2 145579.CAPSD_BPPHM 8.03e-133 403.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_158397_1 1788438.A0A190WHE1_9CIRC 7.94e-18 90.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_421_2 1234888.K0A2R8_9VIRU 2e-40 147.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_304207_1 1396418.BATQ01000039_gene6491 1.44e-110 357.0 28I8X@1|root,2Z8BQ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_109713_1 935565.JAEM01000006_gene3898 7.24e-20 92.8 2C2XN@1|root,32GT6@2|Bacteria,1REZE@1224|Proteobacteria,2U8HW@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM ERF family protein - - - - - - - - - - - - ERF k59_49074_2 1609634.A0A0C5AFT2_9VIRU 4.6e-69 224.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_49074_4 105154.Q9MBU2_9VIRU 1.6e-13 71.2 4QDBB@10239|Viruses,4QUM0@29258|ssDNA viruses,4QP4D@10841|Microviridae 10841|Microviridae S Chlamydia-phage Chp2 scaffold (Chlamy_scaf) - - - - - - - - - - - - - k59_49074_6 105154.Q9MBU6_9VIRU 5.51e-204 585.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_291990_1 1609634.A0A0C5ANA6_9VIRU 2.39e-26 107.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_291990_2 1609634.A0A0C5AFV4_9VIRU 1.55e-34 130.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_73302_1 1385658.U5KPZ6_9VIRU 3.18e-156 459.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_146214_1 1609634.A0A0C5AFV4_9VIRU 1.98e-63 214.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_73321_2 2003327.CAPSD_BPCHP 3.66e-72 248.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_134376_3 1120936.KB907208_gene1089 2.36e-17 89.4 COG3299@1|root,COG3299@2|Bacteria 2|Bacteria S Baseplate J-like protein yqbT1 - - - - - - - - - - - Baseplate_J k59_49505_1 375286.mma_0323 3.8e-27 115.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2VJ57@28216|Betaproteobacteria,4724B@75682|Oxalobacteraceae 28216|Betaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_377645_1 1307759.JOMJ01000004_gene2473 8.68e-16 80.1 29XPE@1|root,30JF0@2|Bacteria,1Q0TH@1224|Proteobacteria,435Z8@68525|delta/epsilon subdivisions,2WXMG@28221|Deltaproteobacteria,2MC96@213115|Desulfovibrionales 28221|Deltaproteobacteria S Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_2 k59_316758_1 1437608.BBIA_1039 1.01e-07 60.1 28MKK@1|root,2ZAWR@2|Bacteria,2IS2W@201174|Actinobacteria,4D1DD@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_110218_1 1692255.A0A0K1RL52_9CIRC 1.33e-16 84.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_292503_4 588581.Cpap_1262 5.49e-16 79.7 292XD@1|root,2ZQEV@2|Bacteria,1V48I@1239|Firmicutes,24GZD@186801|Clostridia 186801|Clostridia S COG NOG18825 non supervised orthologous group - - - - - - - - - - - - - k59_73802_1 1692244.A0A0K1RLR5_9CIRC 4.96e-63 204.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_73802_3 1788439.A0A190WHD0_9CIRC 1.99e-05 48.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_341062_3 1234888.K0A2J2_9VIRU 7.39e-50 175.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_146839_3 665956.HMPREF1032_00687 3.65e-39 146.0 2E2JP@1|root,32XP4@2|Bacteria,1VAIM@1239|Firmicutes,24PPR@186801|Clostridia,3WI4W@541000|Ruminococcaceae 186801|Clostridia S Phage tail protein - - - - - - - - - - - - Sipho_tail k59_159038_3 1283071.R9R4H0_9CAUD 1.36e-43 154.0 4QEMD@10239|Viruses,4R0JN@35237|dsDNA viruses no RNA stage,4QUGF@28883|Caudovirales,4QNXF@10744|Podoviridae 10744|Podoviridae S AAA domain - - - - - - - - - - - - - k59_280743_1 1609634.A0A0C5AFT2_9VIRU 2.39e-59 197.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_316895_3 2003327.CAPSD_BPCHP 6.28e-20 89.7 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_49640_3 1280671.AUJH01000012_gene3166 3.56e-58 214.0 COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,4BYZK@830|Butyrivibrio 186801|Clostridia L DNA polymerase family A - - 2.7.7.7 ko:K02334 - - - - ko00000,ko01000 - - - DNA_pol_A k59_49640_7 1321782.HMPREF1986_02251 1.58e-27 106.0 28J2E@1|root,2Z8YX@2|Bacteria,1TRF9@1239|Firmicutes,249U3@186801|Clostridia,2PSKA@265975|Oribacterium 186801|Clostridia S Protein of unknown function (DUF2815) - - - - - - - - - - - - DUF2815 k59_256089_1 1197951.I6RT34_9CAUD 3.89e-72 233.0 4QGAG@10239|Viruses,4R0KB@35237|dsDNA viruses no RNA stage,4QUA4@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_256091_1 1408473.JHXO01000005_gene1669 3.7e-35 124.0 COG0698@1|root,COG0698@2|Bacteria,4NNSU@976|Bacteroidetes,2FT1X@200643|Bacteroidia 976|Bacteroidetes G Ribose 5-phosphate isomerase rpiB - 5.3.1.6 ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01056,R09030 RC00376,RC00434 ko00000,ko00001,ko00002,ko01000 - - - LacAB_rpiB k59_256091_2 265072.Mfla_1196 9.65e-16 77.4 COG3634@1|root,COG3634@2|Bacteria,1MUKD@1224|Proteobacteria,2VJ01@28216|Betaproteobacteria,2KM80@206350|Nitrosomonadales 206350|Nitrosomonadales C Alkyl hydroperoxide reductase, F subunit - - - ko:K03387 - - - - ko00000,ko01000 - - - Pyr_redox_2,Thioredoxin_3 k59_123607_1 1219035.NT2_13_00580 3.94e-52 185.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_62894_1 223303.REP_PHUV 7.16e-08 62.4 4QB6C@10239|Viruses,4QUKM@29258|ssDNA viruses 10239|Viruses J Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_232699_1 1609634.A0A0C5AFV4_9VIRU 4.82e-67 224.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_135382_2 1692257.A0A0K1RL39_9CIRC 1.98e-77 245.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_1904_2 1234888.K0A2R8_9VIRU 2.05e-30 122.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_220887_1 665942.HMPREF1022_03298 3.08e-53 184.0 COG5410@1|root,COG5410@2|Bacteria,1N0W2@1224|Proteobacteria,42YNM@68525|delta/epsilon subdivisions,2WU2R@28221|Deltaproteobacteria,2MAIS@213115|Desulfovibrionales 28221|Deltaproteobacteria K chromosome segregation - - - - - - - - - - - - - k59_171990_2 1002367.HMPREF0673_02548 6.6e-05 50.1 COG0207@1|root,COG0207@2|Bacteria,4NEC2@976|Bacteroidetes,2FM46@200643|Bacteroidia 976|Bacteroidetes F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k59_330096_1 177439.DP1991 1.56e-57 202.0 COG1040@1|root,COG1040@2|Bacteria,1QV41@1224|Proteobacteria,42Q37@68525|delta/epsilon subdivisions,2WKE3@28221|Deltaproteobacteria,2MMN4@213118|Desulfobacterales 28221|Deltaproteobacteria K competence protein - - - - - - - - - - - - - k59_62905_1 1234888.K0A2J2_9VIRU 9.88e-34 131.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_354422_2 1609634.A0A0C5AFT2_9VIRU 1.8e-66 213.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_38228_2 759938.F5BSB4_9CIRC 2.08e-34 138.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_147686_1 948071.S4S2N2_9CAUD 2.45e-96 299.0 4QH10@10239|Viruses,4QVVN@35237|dsDNA viruses no RNA stage,4QSY9@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_123620_1 1524882.A0A076G6X1_9CAUD 8.92e-67 210.0 4QCB0@10239|Viruses,4QPFH@28883|Caudovirales,4QKQY@10699|Siphoviridae 10699|Siphoviridae S YqaJ-like viral recombinase domain - - - - - - - - - - - - - k59_99206_1 1692252.A0A0K1RL35_9CIRC 3.37e-20 88.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_245662_1 487796.Flav2ADRAFT_0047 6.34e-32 130.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1HXMT@117743|Flavobacteriia 976|Bacteroidetes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_319155_1 1609634.A0A0C5AFV4_9VIRU 1.37e-115 352.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_100055_1 585503.HMPREF7545_1744 1.37e-05 55.1 2DBPZ@1|root,2ZABJ@2|Bacteria,1VJIG@1239|Firmicutes,4H5QI@909932|Negativicutes 909932|Negativicutes - - - - - - - - - - - - - - - k59_51528_1 7029.ACYPI084172-PA 1.9e-10 59.7 2EA4H@1|root,2SGDU@2759|Eukaryota,3A53V@33154|Opisthokonta,3BVUU@33208|Metazoa,3D7Z1@33213|Bilateria,42A75@6656|Arthropoda,3SSKN@50557|Insecta 7029.ACYPI084172-PA|- - - - - - - - - - - - - - - - k59_173042_2 105154.Q9MBU6_9VIRU 7.48e-93 301.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_173042_6 1609634.A0A0C5AFT2_9VIRU 1.31e-15 80.1 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_379504_2 1121445.ATUZ01000011_gene460 4.78e-29 114.0 COG3023@1|root,COG3023@2|Bacteria,1N032@1224|Proteobacteria,432MJ@68525|delta/epsilon subdivisions,2WX9X@28221|Deltaproteobacteria,2MCUI@213115|Desulfovibrionales 28221|Deltaproteobacteria V PFAM N-acetylmuramoyl-L-alanine amidase family 2 - - - - - - - - - - - - Amidase_2 k59_379504_3 690585.JNNU01000002_gene4556 5.37e-06 56.2 COG1573@1|root,COG1573@2|Bacteria,1MW8T@1224|Proteobacteria,2TSAR@28211|Alphaproteobacteria,4BD94@82115|Rhizobiaceae 28211|Alphaproteobacteria L uracil-DNA glycosylase - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - DUF4130,UDG k59_331332_1 1504822.CCNO01000015_gene594 1.01e-49 178.0 COG0553@1|root,COG0863@1|root,COG0553@2|Bacteria,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_64029_7 411460.RUMTOR_02024 8.69e-64 207.0 2A0KC@1|root,30NQJ@2|Bacteria,1V3K4@1239|Firmicutes,24HYK@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_64029_13 665956.HMPREF1032_00688 3.92e-86 272.0 28K55@1|root,2Z9TX@2|Bacteria,1V0P7@1239|Firmicutes,24DCX@186801|Clostridia,3WK99@541000|Ruminococcaceae 186801|Clostridia S Psort location Cytoplasmic, score 7.50 - - - - - - - - - - - - Sipho_Gp37 k59_64029_15 742740.HMPREF9474_02262 2.86e-41 171.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,221IX@1506553|Lachnoclostridium 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_27321_1 263358.VAB18032_02120 2.16e-68 227.0 COG1215@1|root,COG1215@2|Bacteria,2I97V@201174|Actinobacteria,4DF8X@85008|Micromonosporales 201174|Actinobacteria M Glycosyl transferase family group 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2 k59_306922_2 1618237.A0A0C5IMG6_9CIRC 1.1e-21 99.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_223042_3 1609634.A0A0C5AFV4_9VIRU 8.92e-198 569.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_223042_6 1609634.A0A0C5AFT2_9VIRU 8.36e-92 282.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_258953_1 1521187.JPIM01000048_gene86 2.37e-54 189.0 COG0399@1|root,COG0399@2|Bacteria,2G7XI@200795|Chloroflexi 200795|Chloroflexi E DegT/DnrJ/EryC1/StrS aminotransferase family - - - - - - - - - - - - DegT_DnrJ_EryC1 k59_271238_2 145579.H_BPPHM 1.81e-08 60.1 4QCA6@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_271238_3 1609634.A0A0C5AFV4_9VIRU 1.61e-114 353.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_332392_5 2003327.CAPSD_BPCHP 7.15e-43 167.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_380744_1 1618247.A0A0C5IMK7_9CIRC 0.000687 48.5 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_223130_1 1121441.AUCX01000034_gene1565 1.55e-09 67.4 COG4547@1|root,COG4547@2|Bacteria,1QUKX@1224|Proteobacteria,42RTV@68525|delta/epsilon subdivisions,2WNXE@28221|Deltaproteobacteria,2M943@213115|Desulfovibrionales 28221|Deltaproteobacteria H von Willebrand factor, type A - - - - - - - - - - - - CobT,CobT_C,VWA k59_89247_1 33898.JRHJ01000100_gene6199 1.48e-23 103.0 COG3864@1|root,COG3864@2|Bacteria,2GWVA@201174|Actinobacteria 201174|Actinobacteria S VWA-like domain (DUF2201) - - - - - - - - - - - - DUF2201,DUF2201_N k59_271243_1 1322246.BN4_20440 0.000117 49.3 COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2WMQW@28221|Deltaproteobacteria,2M9T9@213115|Desulfovibrionales 28221|Deltaproteobacteria M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB - 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 k59_332394_1 861208.AGROH133_04846 6.38e-41 151.0 COG4653@1|root,COG4653@2|Bacteria,1MWU1@1224|Proteobacteria,2TSSY@28211|Alphaproteobacteria,4B774@82115|Rhizobiaceae 28211|Alphaproteobacteria S phage phi-C31 gp36 major capsid-like protein gp36 - - - - - - - - - - - Phage_capsid k59_4349_1 142661.REP_CACV 1.1e-07 59.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_380748_1 1385658.U5KPZ6_9VIRU 6.78e-66 218.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_28421_1 1415166.NONO_c73550 2.35e-26 104.0 2AYTU@1|root,31EIZ@2|Bacteria,2HI17@201174|Actinobacteria,4G29H@85025|Nocardiaceae 201174|Actinobacteria S Protein of unknown function (DUF2744) - - - - - - - - - - - - DUF2744,IF2_N k59_28421_2 1077144.AGFF01000007_gene2052 6.2e-43 158.0 2ANQ2@1|root,31DPJ@2|Bacteria,2I9V0@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_52727_1 1417296.U879_13410 9.1e-70 237.0 COG3378@1|root,COG3598@1|root,COG3378@2|Bacteria,COG3598@2|Bacteria,1MV7I@1224|Proteobacteria,2TRS2@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Phage plasmid primase P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N k59_284817_5 145579.CAPSD_BPPHM 1.06e-31 130.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_163495_1 1692252.A0A0K1RL35_9CIRC 6.23e-16 80.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_199769_1 1454004.AW11_03831 1.77e-31 127.0 COG4643@1|root,COG4983@1|root,COG4643@2|Bacteria,COG4983@2|Bacteria,1N636@1224|Proteobacteria,2VNYZ@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF3987) - - - - - - - - - - - - DUF3987 k59_78315_1 926550.CLDAP_25590 2.89e-59 206.0 COG1572@1|root,COG1572@2|Bacteria 2|Bacteria NU bacterial-type flagellum-dependent cell motility - - - - - - - - - - - - BatA,CARDB,DUF3367,DUF4091,DUF4159 k59_381945_1 1185766.DL1_00420 3.39e-08 62.8 COG4678@1|root,COG4678@2|Bacteria,1RDU0@1224|Proteobacteria,2U7AC@28211|Alphaproteobacteria 28211|Alphaproteobacteria G N-Acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - - k59_272672_1 1556290.A0A0A0RM00_9CAUD 2.74e-118 361.0 4QAXQ@10239|Viruses,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_369480_2 1692242.A0A0K1RL37_9CIRC 6.64e-09 63.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_224496_2 1385658.U5KPZ6_9VIRU 3.31e-75 242.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_30038_2 509635.N824_24725 1.41e-43 153.0 COG5526@1|root,COG5526@2|Bacteria,4P28W@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - k59_66365_3 1732201.A0A0N9N7I3_9CIRC 5.61e-28 117.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_163599_1 311402.Avi_0103 4.91e-13 73.2 COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,2TUQM@28211|Alphaproteobacteria,4B7ND@82115|Rhizobiaceae 28211|Alphaproteobacteria M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB - 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 k59_226006_1 1100814.G8FS09_9CAUD 5.01e-33 127.0 4QAJ3@10239|Viruses,4QVQ1@35237|dsDNA viruses no RNA stage,4QPYB@28883|Caudovirales,4QKSJ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_261419_1 1437609.BCAL_0624 3.44e-05 49.7 28MKK@1|root,2ZAWR@2|Bacteria,2IS2W@201174|Actinobacteria,4D1DD@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_152808_1 1028800.RG540_CH13810 1.02e-21 95.5 28MSK@1|root,2ZB0X@2|Bacteria,1R7CY@1224|Proteobacteria,2U2MY@28211|Alphaproteobacteria,4BJ92@82115|Rhizobiaceae 28211|Alphaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_237209_1 1618247.A0A0C5IMK7_9CIRC 3.79e-07 57.4 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_164975_2 234621.RER_39750 1.36e-49 167.0 COG3740@1|root,COG3740@2|Bacteria,2HK8H@201174|Actinobacteria,4G80H@85025|Nocardiaceae 201174|Actinobacteria S Caudovirus prohead serine protease - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78 k59_237415_1 472175.EL18_01353 1.03e-64 207.0 COG3772@1|root,COG3772@2|Bacteria,1N3ZC@1224|Proteobacteria 1224|Proteobacteria S lysozyme - - - - - - - - - - - - - k59_153036_4 1168547.L7P648_9CIRC 5.7e-47 167.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_31512_1 485918.Cpin_3834 4.52e-78 240.0 COG0270@1|root,COG0270@2|Bacteria,4NRFG@976|Bacteroidetes,1IY5U@117747|Sphingobacteriia 976|Bacteroidetes L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_31512_2 1121286.AUMT01000001_gene32 6.15e-139 405.0 COG0270@1|root,COG0270@2|Bacteria,4P3IR@976|Bacteroidetes 976|Bacteroidetes H C-5 cytosine-specific DNA methylase - - - - - - - - - - - - DNA_methylase k59_115934_2 396588.Tgr7_0386 2.69e-15 79.7 COG1345@1|root,COG1345@2|Bacteria,1QZZ9@1224|Proteobacteria 1224|Proteobacteria N Prophage tail length tape measure protein - - - - - - - - - - - - TMP_2 k59_383053_2 1475143.W8SNN0_9CIRC 2.65e-19 91.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_298966_1 1107311.Q767_10995 1.02e-19 93.2 COG4935@1|root,COG4935@2|Bacteria,4PPGZ@976|Bacteroidetes,1IKMN@117743|Flavobacteriia,2NV5K@237|Flavobacterium 976|Bacteroidetes O Reprolysin (M12B) family zinc metalloprotease - - - - - - - - - - - - CUB,Reprolysin_5 k59_92656_1 373415.Q19Y14_9CAUD 3.3e-40 137.0 4QFPC@10239|Viruses,4QXCG@35237|dsDNA viruses no RNA stage,4QPQC@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_384412_1 547559.Nmag_2114 3.78e-11 70.1 arCOG10745@1|root,arCOG10745@2157|Archaea,2XUC2@28890|Euryarchaeota,23S1C@183963|Halobacteria 183963|Halobacteria C molybdopterin cofactor binding - - - - - - - - - - - - - k59_289575_3 1211640.K4JUD3_9CAUD 2.61e-73 234.0 4QB08@10239|Viruses,4QY8E@35237|dsDNA viruses no RNA stage,4QRIV@28883|Caudovirales,4QM5X@10699|Siphoviridae 10699|Siphoviridae S exonuclease activity - - - - - - - - - - - - - k59_300563_1 1618248.A0A0C5IB82_9CIRC 3.22e-21 97.8 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_166164_2 1380346.JNIH01000064_gene5212 2.13e-25 107.0 COG5301@1|root,COG5301@2|Bacteria,2ISHQ@201174|Actinobacteria 201174|Actinobacteria G cellulose 1,4-beta-cellobiosidase activity - - - - - - - - - - - - - k59_348737_1 1476583.DEIPH_ctg017orf0233 1.39e-11 73.6 COG2369@1|root,COG4695@1|root,COG2369@2|Bacteria,COG4695@2|Bacteria 2|Bacteria N Portal protein yqbB3 - - - - - - - - - - - Phage_Mu_F,Phage_portal k59_187742_1 394.NGR_c11420 7.26e-11 72.4 COG1409@1|root,COG1409@2|Bacteria 2|Bacteria S acid phosphatase activity - - - - - - - - - - - - Big_5,Collagen,Peptidase_S74 k59_202681_1 886379.AEWI01000043_gene3315 1.8e-16 92.0 COG3866@1|root,COG3866@2|Bacteria,4P09P@976|Bacteroidetes,2FNQB@200643|Bacteroidia,3XKR0@558415|Marinilabiliaceae 976|Bacteroidetes G pectate lyase K01728 - - - - - - - - - - - - - k59_348741_1 910314.HMPREF9220_0743 4.7e-20 101.0 COG5108@1|root,COG5108@2|Bacteria 2|Bacteria K dna-directed rna polymerase - - 2.7.7.6 ko:K08309,ko:K10908,ko:K21313 - - - - ko00000,ko01000,ko01011,ko03029,ko03200 - GH23 - RNA_pol,RPOL_N k59_154476_1 1234888.K0A2J2_9VIRU 4.38e-17 86.3 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_312191_1 220341.16506051 8.09e-49 177.0 COG1783@1|root,COG1783@2|Bacteria,1MWGP@1224|Proteobacteria,1S8D6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_324764_1 1385658.U5KPZ6_9VIRU 1.33e-66 219.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_130200_1 1121937.AUHJ01000009_gene1510 1.13e-50 181.0 COG0823@1|root,COG0823@2|Bacteria,1R4CN@1224|Proteobacteria,1S0NH@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - PD40 k59_300737_1 186617.M9M8L2_9VIRU 3.22e-48 168.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_143436_1 933262.AXAM01000071_gene2218 5.22e-19 86.3 28XPA@1|root,2ZJK5@2|Bacteria,1P9T2@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_95659_1 439292.Bsel_3022 6.95e-48 174.0 COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,4HCHZ@91061|Bacilli 91061|Bacilli T Virulence-associated protein E - - - - - - - - - - - - VirE k59_188767_1 203122.Sde_0401 1.45e-14 75.5 28H65@1|root,2Z7IN@2|Bacteria,1Q4IY@1224|Proteobacteria,1RZHE@1236|Gammaproteobacteria,46703@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - Phage_lambda_P k59_34347_1 1147150.K7PM60_9CAUD 1.49e-36 132.0 4QB1F@10239|Viruses,4QUYH@35237|dsDNA viruses no RNA stage,4QPSW@28883|Caudovirales,4QKPW@10699|Siphoviridae 10699|Siphoviridae S exonuclease activity - - - - - - - - - - - - - k59_34347_2 1357275.AVEL02000135_gene43 3.73e-31 113.0 2DM6W@1|root,32UGB@2|Bacteria,1N425@1224|Proteobacteria,1SB1W@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3168) - - - - - - - - - - - - DUF3168 k59_20507_1 870967.VIS19158_15144 6.28e-19 94.7 2AWK2@1|root,31NGS@2|Bacteria,1QK7Q@1224|Proteobacteria,1TIAZ@1236|Gammaproteobacteria,1XYSI@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - k59_349987_2 234621.RER_25220 2.76e-07 60.8 COG3941@1|root,COG3941@2|Bacteria 2|Bacteria O tape measure - - - - - - - - - - - - Tape_meas_lam_C k59_95667_1 105154.Q9MBU0_9VIRU 1.42e-12 69.7 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_313547_1 2003327.REP_BPCHP 4.97e-18 87.8 4QCVK@10239|Viruses,4QUMV@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_70642_1 1609634.A0A0C5AFT2_9VIRU 2.59e-33 127.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_70642_3 1609634.A0A0C5AFV4_9VIRU 2.8e-101 317.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_302068_1 936136.ARRT01000006_gene5340 1.46e-77 250.0 COG1783@1|root,COG1783@2|Bacteria,1RAGC@1224|Proteobacteria,2U6JF@28211|Alphaproteobacteria,4BID4@82115|Rhizobiaceae 28211|Alphaproteobacteria S phage Terminase large subunit - - - - - - - - - - - - - k59_95671_2 107635.AZUO01000001_gene908 7.59e-09 60.1 28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TURR@28211|Alphaproteobacteria,36XR3@31993|Methylocystaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_156090_2 439375.Oant_0212 6.79e-11 63.5 2EGVX@1|root,33AN5@2|Bacteria,1NP9T@1224|Proteobacteria,2UMSD@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_362709_1 268746.Q58MN3_BPPRM 4.42e-22 97.8 4QDJF@10239|Viruses,4QVQ0@35237|dsDNA viruses no RNA stage,4QR89@28883|Caudovirales,4QICF@10662|Myoviridae 10662|Myoviridae S Virus neck protein - GO:0005575,GO:0019012 - - - - - - - - - - - k59_189940_1 194699.Q775C7_BPBPP 6.09e-94 286.0 4QH0X@10239|Viruses,4QXIJ@35237|dsDNA viruses no RNA stage,4QSY6@28883|Caudovirales,4QNTU@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_72309_1 1229205.BUPH_02619 2.13e-105 332.0 COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,2VHBK@28216|Betaproteobacteria,1K5QM@119060|Burkholderiaceae 28216|Betaproteobacteria V N-6 DNA Methylase - - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,N6_Mtase k59_278391_1 1391038.T1YSF1_9VIRU 1.02e-90 276.0 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_278391_3 1699094.A0A0K1P922_9VIRU 3.91e-51 175.0 4QAZA@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_278391_4 1792832.A0A125R3J8_9VIRU 4.49e-61 196.0 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_303559_2 765698.Mesci_3835 1.24e-69 235.0 COG5323@1|root,COG5323@2|Bacteria,1R049@1224|Proteobacteria 1224|Proteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6 k59_181861_1 864051.BurJ1DRAFT_2475 1.29e-29 121.0 COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2VIE0@28216|Betaproteobacteria,1KJYI@119065|unclassified Burkholderiales 28216|Betaproteobacteria H DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5 k59_230737_1 1033743.CAES01000033_gene1065 5.56e-05 51.2 COG5434@1|root,COG5434@2|Bacteria 2|Bacteria M polygalacturonase activity - - - - - - - - - - - - Beta_helix,F5_F8_type_C,Laminin_G_3,Pectate_lyase_3,SLH k59_339854_1 1385658.U5KPZ6_9VIRU 1.48e-61 207.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_315112_1 1304877.KI519399_gene4996 3.98e-134 467.0 COG0454@1|root,COG0827@1|root,COG1203@1|root,COG0456@2|Bacteria,COG0827@2|Bacteria,COG1203@2|Bacteria,1QZ6D@1224|Proteobacteria,2U5JW@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA restriction-modification system - - - - - - - - - - - - AAA_34 k59_362931_1 268747.Q58LL8_BPPRS 4.01e-25 118.0 4QBUC@10239|Viruses,4QVRG@35237|dsDNA viruses no RNA stage,4QQGQ@28883|Caudovirales,4QHY3@10662|Myoviridae 10662|Myoviridae - - - - - - - - - - - - - - - k59_22109_2 318586.Pden_4094 4.2e-15 82.4 2E8SI@1|root,3333B@2|Bacteria,1N7MG@1224|Proteobacteria,2UJSF@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_157570_1 1026882.MAMP_01134 5.12e-06 58.5 COG3378@1|root,COG3378@2|Bacteria 2|Bacteria KL Phage plasmid primase P4 family - - - ko:K06919 - - - - ko00000 - - - PriCT_2,Prim-Pol k59_157570_3 417280.A1YZY2_9CAUD 1.08e-126 406.0 4QCZC@10239|Viruses,4QX3V@35237|dsDNA viruses no RNA stage,4QRH3@28883|Caudovirales,4QHVR@10662|Myoviridae 10662|Myoviridae S Bacterial DNA polymerase III alpha subunit - - - - - - - - - - - - - k59_351657_3 420662.Mpe_B0283 2.68e-128 388.0 COG1389@1|root,COG1389@2|Bacteria,1P37I@1224|Proteobacteria 1224|Proteobacteria L DNA topoisomerase II activity - - - - - - - - - - - - - k59_328801_1 1379698.RBG1_1C00001G0977 2.73e-33 127.0 COG0305@1|root,COG0305@2|Bacteria,2NNKG@2323|unclassified Bacteria 2|Bacteria L Participates in initiation and elongation during chromosome replication dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_304458_3 375286.mma_2206 6.92e-126 379.0 COG5323@1|root,COG5323@2|Bacteria 2|Bacteria M Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6 k59_304458_4 49964.Q94MS4_9CAUD 5.67e-145 446.0 4QCUF@10239|Viruses,4QV7U@35237|dsDNA viruses no RNA stage,4QQ89@28883|Caudovirales,4QNCY@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_97853_1 105154.Q9MBU6_9VIRU 1.18e-89 285.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_340774_3 1609634.A0A0C5ANA6_9VIRU 1.69e-14 76.6 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_122229_1 1234888.K0A2J2_9VIRU 5.44e-110 339.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_255759_1 1519439.JPJG01000116_gene2028 1.46e-05 52.0 COG0863@1|root,COG0863@2|Bacteria,1TR56@1239|Firmicutes,248NR@186801|Clostridia,2N7Y1@216572|Oscillospiraceae 186801|Clostridia L DNA methylase cfr9IM - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_304568_1 1226994.AMZB01000137_gene5410 6.43e-16 83.2 2CYA9@1|root,32T3V@2|Bacteria,1RGRN@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_170769_1 650150.ERH_1292 6.05e-09 64.3 28MKK@1|root,2ZAWR@2|Bacteria,1UYAT@1239|Firmicutes,3VSD5@526524|Erysipelotrichia 526524|Erysipelotrichia S Putative viral replication protein - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_802_4 511.JT27_18335 1.92e-10 70.9 COG0305@1|root,COG0305@2|Bacteria,1NY8T@1224|Proteobacteria 1224|Proteobacteria L DnaB-like helicase C terminal domain - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_C k59_340903_1 1250005.PHEL85_2452 3.48e-39 149.0 COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1HXHB@117743|Flavobacteriia,3VVTA@52959|Polaribacter 976|Bacteroidetes F Ribonucleotide reductase, all-alpha domain nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN k59_1576_1 1071177.G3ENB0_9CAUD 2.42e-05 52.8 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - GO:0003674,GO:0003824,GO:0005575,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019012,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 - - - - - - - - - - - k59_98726_1 1234888.K0A2J2_9VIRU 4.34e-27 113.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_268848_1 1788438.A0A190WHE1_9CIRC 1.72e-24 105.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_378194_1 1100720.ALKN01000018_gene1739 2.45e-77 244.0 28J3M@1|root,2Z8ZT@2|Bacteria,1Q2A4@1224|Proteobacteria,2VNFP@28216|Betaproteobacteria,4A9TU@80864|Comamonadaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_378194_2 1175654.A0A0S0NAE1_9CAUD 7.07e-11 67.0 4QB0T@10239|Viruses,4QV4X@35237|dsDNA viruses no RNA stage,4QPUT@28883|Caudovirales,4QKQK@10699|Siphoviridae 10699|Siphoviridae S Protein of unknown function (DUF669) - - - - - - - - - - - - - k59_281692_3 1609634.A0A0C5AFT2_9VIRU 1.64e-46 161.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_317821_3 1618254.A0A0C5IBG4_9CIRC 4.66e-115 338.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_365982_3 1618236.A0A0C5IB23_9CIRC 2.01e-15 82.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_378289_1 323848.Nmul_A1436 3.85e-07 63.2 2E3N6@1|root,32YKC@2|Bacteria,1NDBP@1224|Proteobacteria,2VXQM@28216|Betaproteobacteria,372YA@32003|Nitrosomonadales 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_281704_2 1378168.N510_02468 1.97e-13 71.2 COG4675@1|root,COG4675@2|Bacteria,1VH1P@1239|Firmicutes 1239|Firmicutes S tail collar domain protein - - - - - - - - - - - - - k59_354207_12 631454.N177_1465 1.28e-26 106.0 29CWT@1|root,2ZZUX@2|Bacteria,1REF2@1224|Proteobacteria,2U7K7@28211|Alphaproteobacteria,1JQ26@119043|Rhodobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2585) - - - - - - - - - - - - DUF2585 k59_51399_1 926550.CLDAP_36010 8.61e-17 83.6 COG3103@1|root,COG3103@2|Bacteria 2|Bacteria T Sh3 type 3 domain protein - - 3.5.1.28 ko:K01448,ko:K07448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko02048,ko03036 - - - Muraidase,SH3_3,SLH k59_366946_2 1234888.K0A2J2_9VIRU 1.65e-82 266.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_306664_1 1250005.PHEL85_3300 2.59e-12 74.3 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1HXMT@117743|Flavobacteriia,3VVBS@52959|Polaribacter 976|Bacteroidetes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_75646_3 526222.Desal_2558 4.41e-42 156.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,42QA8@68525|delta/epsilon subdivisions,2WJBW@28221|Deltaproteobacteria,2M8NS@213115|Desulfovibrionales 28221|Deltaproteobacteria S PFAM ATPase associated with various cellular activities - - - - - - - - - - - - AAA_3,AAA_5 k59_379432_1 1379710.S5TNC2_9CIRC 1.47e-16 84.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_379432_2 1618238.A0A0C5I2G8_9CIRC 2.48e-08 61.6 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_245560_1 1385658.U5KPZ6_9VIRU 6.53e-89 280.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_112037_1 1313421.JHBV01000016_gene5476 4.79e-26 115.0 2CDGZ@1|root,34CGM@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_221900_1 1692249.A0A0K1RL40_9CIRC 2.11e-19 87.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_136362_1 1120936.KB907208_gene1107 1.84e-63 213.0 COG0209@1|root,COG0209@2|Bacteria,2IC1H@201174|Actinobacteria 201174|Actinobacteria F Ribonucleotide reductase, barrel domain - - - - - - - - - - - - Ribonuc_red_lgC k59_38916_1 1618248.A0A0C5IB82_9CIRC 6.05e-50 171.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_136364_1 1188256.BASI01000007_gene2321 3.95e-27 114.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage terminase-like protein large subunit - - - - - - - - - - - - Terminase_1 k59_148397_3 186617.M9M8L2_9VIRU 1.37e-63 212.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_379443_1 670487.Ocepr_2254 1.67e-14 79.0 COG0553@1|root,COG0553@2|Bacteria,1WKWF@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus V DEAD-like helicases superfamily - - - - - - - - - - - - Helicase_C k59_367124_2 1197951.I6S2A3_9CAUD 4.21e-38 140.0 4QAIV@10239|Viruses,4QYFZ@35237|dsDNA viruses no RNA stage,4QQUY@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_136452_3 1122201.AUAZ01000017_gene2962 3.31e-15 88.2 COG4675@1|root,COG4675@2|Bacteria 2|Bacteria M tail collar domain protein - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - Collar,Phage_fiber_2 k59_368235_1 349161.Dred_1189 9.02e-33 123.0 28J2E@1|root,2Z8YX@2|Bacteria,1TRF9@1239|Firmicutes,249U3@186801|Clostridia 186801|Clostridia S Protein of unknown function (DUF2815) - - - - - - - - - - - - DUF2815 k59_332359_1 1123321.KB905821_gene4281 5.9e-06 49.3 COG3291@1|root,COG3291@2|Bacteria,2IHHS@201174|Actinobacteria 201174|Actinobacteria S Pkd domain containing protein - - - - - - - - - - - - - k59_198369_1 1144310.PMI07_002360 2.28e-09 66.6 2DPZ1@1|root,3340X@2|Bacteria,1R2EE@1224|Proteobacteria,2TZIB@28211|Alphaproteobacteria,4BP2Q@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_89207_1 1380394.JADL01000008_gene3768 5.6e-27 119.0 COG3064@1|root,COG3064@2|Bacteria,1R6JV@1224|Proteobacteria,2U5NE@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Membrane - - - - - - - - - - - - - k59_4288_1 105154.Q9MBU6_9VIRU 2.39e-37 142.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_101390_5 1115512.EH105704_01_02770 1.24e-33 128.0 COG0629@1|root,COG0629@2|Bacteria,1RC22@1224|Proteobacteria,1S2A9@1236|Gammaproteobacteria 1236|Gammaproteobacteria L ERF superfamily - - - - - - - - - - - - ERF k59_101390_6 1121366.KB892443_gene1946 2.6e-12 68.6 COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,22K8T@1653|Corynebacteriaceae 201174|Actinobacteria L Single-stranded DNA-binding protein ssb GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071944,GO:0097159,GO:1901363 - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_40268_2 926569.ANT_06340 1.18e-25 105.0 COG1086@1|root,COG1086@2|Bacteria,2G8BP@200795|Chloroflexi 200795|Chloroflexi M NmrA-like family - - - - - - - - - - - - Polysacc_synt_2 k59_332467_1 1618258.A0A0C5I9K3_9CIRC 1.3e-16 82.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_332467_3 1618241.A0A0C5I2I4_9CIRC 9.89e-42 147.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_284895_1 1227349.C170_12550 1.09e-27 118.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,26QTS@186822|Paenibacillaceae 91061|Bacilli L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon k59_198527_1 1379725.S5TMY9_9CIRC 3.59e-33 133.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_77045_2 662755.CRES_2134 4.17e-10 61.2 COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,22K8T@1653|Corynebacteriaceae 201174|Actinobacteria L Single-stranded DNA-binding protein ssb GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071944,GO:0097159,GO:1901363 - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_149947_1 1408418.JNJH01000043_gene3127 1.05e-61 202.0 2FITE@1|root,34AIX@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_174484_1 391009.Tmel_1457 1.17e-13 78.6 29ZN0@1|root,30MNI@2|Bacteria 2|Bacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_101541_1 1609634.A0A0C5ANA6_9VIRU 2.47e-26 105.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_151478_4 262316.MAP_0859c 5.13e-53 176.0 COG4186@1|root,COG4186@2|Bacteria,2IRS9@201174|Actinobacteria,23DYC@1762|Mycobacteriaceae 201174|Actinobacteria S Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos,Metallophos_2 k59_286724_2 1219035.NT2_13_00580 6.03e-44 164.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_333844_4 1961.JOAK01000020_gene7320 8.26e-08 53.9 COG3864@1|root,COG3864@2|Bacteria,2GWVA@201174|Actinobacteria 201174|Actinobacteria S VWA-like domain (DUF2201) - - - - - - - - - - - - DUF2201,DUF2201_N k59_54172_7 1120936.KB907208_gene1066 1.15e-88 280.0 28MN1@1|root,2ZAXN@2|Bacteria,2H2TF@201174|Actinobacteria 201174|Actinobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6C k59_78528_1 32057.KB217480_gene8072 3.55e-14 75.5 COG1196@1|root,COG1196@2|Bacteria,1GEKG@1117|Cyanobacteria,1HNKS@1161|Nostocales 1117|Cyanobacteria D DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - Dam k59_30258_1 1313421.JHBV01000038_gene2850 5.69e-08 55.1 COG3409@1|root,COG3409@2|Bacteria,4PPDF@976|Bacteroidetes 976|Bacteroidetes M Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_1 k59_30258_3 744980.TRICHSKD4_4529 6.65e-15 82.4 COG4675@1|root,COG4675@2|Bacteria,1N0FZ@1224|Proteobacteria,2UDXB@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage Tail Collar Domain - - - - - - - - - - - - Collar k59_321900_1 1234888.K0A2J2_9VIRU 2.07e-49 175.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_16731_8 1118054.CAGW01000095_gene4680 5.07e-11 60.1 2EI4V@1|root,33BW7@2|Bacteria,1VKQH@1239|Firmicutes,4HRPN@91061|Bacilli 91061|Bacilli S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_5860_1 1101189.AQUO01000001_gene2294 1.92e-05 49.3 COG1943@1|root,COG1943@2|Bacteria,1P8IT@1224|Proteobacteria,2TRKV@28211|Alphaproteobacteria,2PWVD@265|Paracoccus 28211|Alphaproteobacteria L Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_2 k59_5860_2 189753.AXAS01000006_gene2244 4.96e-32 121.0 2F14A@1|root,33U5N@2|Bacteria,1RJ2V@1224|Proteobacteria 1224|Proteobacteria S Methyltransferase domain - - - - - - - - - - - - Methyltransf_23 k59_91035_1 665950.HMPREF1025_02633 9.25e-45 160.0 28HHC@1|root,2Z7T2@2|Bacteria,1TR3B@1239|Firmicutes,24D5P@186801|Clostridia,27KWD@186928|unclassified Lachnospiraceae 186801|Clostridia S AAA domain - - - - - - - - - - - - AAA_24 k59_91035_2 1140001.I571_01812 3.19e-97 301.0 COG1196@1|root,COG1196@2|Bacteria,1TSKM@1239|Firmicutes,4I7Z5@91061|Bacilli,4B103@81852|Enterococcaceae 91061|Bacilli D AAA domain - - - - - - - - - - - - AAA_23 k59_78529_1 1121448.DGI_0672 1.57e-32 138.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,2M7UN@213115|Desulfovibrionales 28221|Deltaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_176024_2 240016.ABIZ01000001_gene3401 3.67e-44 157.0 2E0FE@1|root,32W1M@2|Bacteria,46TEN@74201|Verrucomicrobia,2IVPU@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_127368_1 1692252.A0A0K1RLN6_9CIRC 1.58e-23 100.0 4QCY8@10239|Viruses,4QUMD@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_91036_1 691965.D4P7L7_9CAUD 1.64e-109 344.0 4QB9J@10239|Viruses,4QXFE@35237|dsDNA viruses no RNA stage,4QS1Z@28883|Caudovirales,4QN8F@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_236248_2 1123519.PSJM300_14835 1.31e-42 160.0 COG0464@1|root,COG0464@2|Bacteria,1QU82@1224|Proteobacteria,1SA9J@1236|Gammaproteobacteria,1Z2EZ@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria O Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_286910_2 1609634.A0A0C5AFV4_9VIRU 4.45e-26 107.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_274200_3 411460.RUMTOR_01339 1.42e-33 124.0 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_274200_5 411460.RUMTOR_01335 1.77e-112 368.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_335234_1 1357279.N018_13055 2.97e-59 192.0 2E0AI@1|root,32VXW@2|Bacteria,1N2A1@1224|Proteobacteria,1SAFV@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_67969_1 1609634.A0A0C5AFV4_9VIRU 8.26e-50 175.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_359159_1 887327.HMPREF0476_1911 4.84e-13 77.8 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2VJ57@28216|Betaproteobacteria,2KPWN@206351|Neisseriales 206351|Neisseriales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_92899_2 1986029.Q9MBM3_9VIRU 4.55e-37 136.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_214508_1 717772.THIAE_06065 2.74e-19 87.8 2A0ES@1|root,30NII@2|Bacteria,1REA8@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_201569_1 488538.SAR116_0382 5.91e-74 243.0 28S81@1|root,2ZEJD@2|Bacteria,1RCNN@1224|Proteobacteria,2U6Z0@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_92903_2 1609634.A0A0C5ANA6_9VIRU 0.000165 47.0 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_69801_4 1220535.IMCC14465_11060 2.09e-17 78.2 COG3108@1|root,COG3108@2|Bacteria,1QDAN@1224|Proteobacteria,2UUNY@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Bacterial protein of unknown function (DUF882) - - - - - - - - - - - - Peptidase_M15_3 k59_57335_1 1379695.S5SXZ1_9CIRC 1.01e-17 94.0 4QD5V@10239|Viruses 10239|Viruses S Viral coat protein (S domain) - GO:0003674,GO:0003676,GO:0003723,GO:0005198,GO:0005488,GO:0005509,GO:0005575,GO:0008289,GO:0019012,GO:0019028,GO:0019030,GO:0039617,GO:0039660,GO:0043167,GO:0043169,GO:0044423,GO:0046872,GO:0097159,GO:1901363 - - - - - - - - - - - k59_57335_2 1379712.S5TMV9_9CIRC 2.33e-20 96.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_33493_1 742725.HMPREF9450_02123 1.41e-36 143.0 COG1196@1|root,COG1196@2|Bacteria,4NMBI@976|Bacteroidetes,2FR6N@200643|Bacteroidia 976|Bacteroidetes D nuclear chromosome segregation - - - - - - - - - - - - - k59_290073_2 1415780.JPOG01000001_gene442 2.59e-12 75.1 COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,1S054@1236|Gammaproteobacteria,1XBY3@135614|Xanthomonadales 135614|Xanthomonadales H DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_301111_2 1123371.ATXH01000021_gene1117 1.73e-33 135.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GHDG@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_142549_1 1461694.ATO9_03915 5.05e-14 70.5 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2TU8N@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_228076_2 1122931.AUAE01000008_gene4048 1.46e-15 81.6 COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,2FNFH@200643|Bacteroidia,231UH@171551|Porphyromonadaceae 976|Bacteroidetes L DnaB-like helicase N terminal domain - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_290075_1 1618258.A0A0C5I9K3_9CIRC 3.95e-12 75.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_155030_2 211165.AJLN01000015_gene2293 2.7e-19 104.0 COG0328@1|root,COG1539@1|root,COG0328@2|Bacteria,COG1539@2|Bacteria,1G326@1117|Cyanobacteria,1JGRS@1189|Stigonemataceae 1117|Cyanobacteria L RNA-DNA hybrid ribonuclease activity - - - - - - - - - - - - - k59_301123_2 861044.E0YPX0_9CAUD 1.79e-13 71.6 4QB02@10239|Viruses,4QUYT@35237|dsDNA viruses no RNA stage,4QRX7@28883|Caudovirales,4QKY2@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_45125_1 673862.BABL1_662 2.35e-23 117.0 COG3209@1|root,COG5184@1|root,COG3209@2|Bacteria,COG5184@2|Bacteria,1QW4H@1224|Proteobacteria,42ZEZ@68525|delta/epsilon subdivisions,2WT5G@28221|Deltaproteobacteria 1224|Proteobacteria M Immunoglobulin-like repeats containing protein domain - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - Autotransporter,Big_3_5,DUF4347,He_PIG,RHS_repeat k59_251667_1 1123508.JH636439_gene766 5.78e-30 122.0 COG0553@1|root,COG0553@2|Bacteria,2IX46@203682|Planctomycetes 203682|Planctomycetes KL helicase superfamily c-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N,SWIM k59_384886_1 478749.BRYFOR_08522 1.35e-57 192.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_82017_1 1144310.PMI07_002360 1.25e-16 87.4 2DPZ1@1|root,3340X@2|Bacteria,1R2EE@1224|Proteobacteria,2TZIB@28211|Alphaproteobacteria,4BP2Q@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_119281_7 756275.H2BCT8_9CAUD 1.94e-15 86.3 4QMPJ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_168158_1 1123057.P872_18430 4.78e-08 59.7 29YBT@1|root,30K65@2|Bacteria,4NY8W@976|Bacteroidetes,47SZM@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_241061_1 536019.Mesop_3364 0.000758 51.2 COG5301@1|root,COG5301@2|Bacteria,1QW67@1224|Proteobacteria,2UGK8@28211|Alphaproteobacteria 28211|Alphaproteobacteria G cellulose 1,4-beta-cellobiosidase activity - - - - - - - - - - - - PTR k59_241061_7 1267533.KB906733_gene3133 1.28e-10 65.9 COG5549@1|root,COG5549@2|Bacteria,3Y7J6@57723|Acidobacteria,2JMQZ@204432|Acidobacteriia 204432|Acidobacteriia O Zinc-dependent metalloprotease - - - - - - - - - - - - - k59_107667_2 1618260.A0A0C5I2C5_9CIRC 4.61e-40 148.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_277662_1 1028800.RG540_CH13580 2.88e-36 142.0 COG5108@1|root,COG5108@2|Bacteria,1PIWB@1224|Proteobacteria,2U1JR@28211|Alphaproteobacteria,4BC0X@82115|Rhizobiaceae 28211|Alphaproteobacteria K DNA-directed RNA polymerase N-terminal - - - - - - - - - - - - RNA_pol,RPOL_N k59_156755_1 1618260.A0A0C5I2C5_9CIRC 2.07e-20 94.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_314422_2 1502724.FF80_03116 1.51e-74 238.0 COG0175@1|root,COG0175@2|Bacteria,1QZJ1@1224|Proteobacteria,2U233@28211|Alphaproteobacteria 28211|Alphaproteobacteria EH sulfate reduction - - - - - - - - - - - - - k59_314425_1 69279.BG36_20845 4.04e-39 145.0 2C5GI@1|root,2Z8C1@2|Bacteria,1R8XM@1224|Proteobacteria,2TUME@28211|Alphaproteobacteria 28211|Alphaproteobacteria S P22 coat protein - gene protein 5 - - - - - - - - - - - - P22_CoatProtein k59_291415_3 145579.CAPSD_BPPHM 2.06e-75 244.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_265098_1 222534.KB893796_gene2604 5.92e-55 182.0 28HEE@1|root,2Z7QU@2|Bacteria,2I1I5@201174|Actinobacteria 201174|Actinobacteria S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_314620_1 55529.EKX42401 5.82e-07 57.0 COG0553@1|root,KOG1000@2759|Eukaryota 2759|Eukaryota L annealing helicase activity - - 3.6.4.12 ko:K14440 - - - - ko00000,ko01000,ko03036 - - - HARP,Helicase_C,SNF2_N k59_21493_1 1433287.X808_8900 5.24e-22 93.6 2CC49@1|root,2ZBQQ@2|Bacteria,1RA92@1224|Proteobacteria,1S3BM@1236|Gammaproteobacteria,1YA38@135625|Pasteurellales 135625|Pasteurellales S Protein of unknown function (DUF1367) - - - - - - - - - - - - DUF1367 k59_96850_1 145579.REP_BPPHM 1.75e-28 117.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_230187_1 105154.Q9MBU3_9VIRU 8.6e-08 58.2 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_230187_3 105154.Q9MBU6_9VIRU 9.2e-135 405.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_181378_1 765869.BDW_00900 3.69e-06 59.3 COG2911@1|root,COG3209@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,1QY1R@1224|Proteobacteria,43C93@68525|delta/epsilon subdivisions,2MUT2@213481|Bdellovibrionales,2X7JI@28221|Deltaproteobacteria 213481|Bdellovibrionales M cell wall surface anchor family protein - - - - - - - - - - - - Peptidase_S74 k59_189539_2 395961.Cyan7425_2019 1.41e-09 67.4 COG1091@1|root,COG2723@1|root,COG1091@2|Bacteria,COG2723@2|Bacteria,1G1CP@1117|Cyanobacteria,3KGFE@43988|Cyanothece 2|Bacteria C Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose rfbD - 1.1.1.133,3.2.1.21 ko:K00067,ko:K05350 ko00460,ko00500,ko00521,ko00523,ko00940,ko01100,ko01110,ko01130,map00460,map00500,map00521,map00523,map00940,map01100,map01110,map01130 M00793 R00026,R02558,R02777,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00182,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_1,RmlD_sub_bind k59_83868_1 484895.A9J702_BPLUZ 1.91e-12 66.6 4QGGJ@10239|Viruses,4R0EM@35237|dsDNA viruses no RNA stage,4QTQW@28883|Caudovirales,4QNRW@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_121071_1 877240.E1AC06_9CAUD 0.000136 44.7 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_388321_1 1385658.U5KPZ6_9VIRU 6.38e-106 327.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_388321_2 1609634.A0A0C5ANA6_9VIRU 5.37e-08 58.9 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_388321_7 1385658.U5KPZ6_9VIRU 4.49e-87 274.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_266916_4 76636.JOEC01000001_gene1138 1.74e-61 211.0 2AYQQ@1|root,31QVM@2|Bacteria,2HT0W@201174|Actinobacteria,4FR6P@85023|Microbacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - k59_266916_9 1172188.KB911820_gene2845 1.18e-29 111.0 2F5XY@1|root,33YGK@2|Bacteria,2H6A2@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_266916_10 1136534.J9PUM4_9CAUD 1.07e-69 235.0 4QY3P@35237|dsDNA viruses no RNA stage,4QQ7H@28883|Caudovirales,4QK0H@10662|Myoviridae 10662|Myoviridae S Terminase-like family - - - - - - - - - - - - - k59_388323_1 1234888.K0A2J2_9VIRU 6.47e-90 286.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_388323_7 1234888.K0A2J2_9VIRU 5.71e-32 124.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_191124_2 1385658.U5KPZ6_9VIRU 1.37e-214 611.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_191124_4 105154.Q9MBU3_9VIRU 5.12e-07 55.5 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_266960_1 1986029.Q9MBM8_9VIRU 1.04e-44 159.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_266960_2 145579.H_BPPHM 2.72e-08 60.5 4QCA6@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_388324_3 1385658.U5KPZ6_9VIRU 3.51e-134 407.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_266964_1 29540.C481_08216 5.03e-11 67.8 COG1573@1|root,arCOG00905@2157|Archaea,2XUC0@28890|Euryarchaeota,23TCN@183963|Halobacteria 183963|Halobacteria L Phage SPO1 DNA - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_191137_2 1618247.A0A0C5IMK7_9CIRC 7.68e-06 49.3 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_388325_2 66366.REP_TYLCI 1.39e-18 94.7 4QB6C@10239|Viruses,4QUKM@29258|ssDNA viruses 10239|Viruses J Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_388326_1 1618257.A0A0C5IBI9_9CIRC 3.63e-48 168.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388440_3 1618248.A0A0C5IB82_9CIRC 7.7e-09 60.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_328607_2 1349767.GJA_1460 3.58e-13 75.9 2C96H@1|root,2Z7Q6@2|Bacteria,1PQG4@1224|Proteobacteria,2W1VI@28216|Betaproteobacteria 28216|Betaproteobacteria S Sulfotransferase domain - - - ko:K13472 ko04626,map04626 - - - ko00000,ko00001 - - - Sulfotransfer_3 k59_97655_1 742733.HMPREF9469_05032 7.85e-131 389.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia,221RR@1506553|Lachnoclostridium 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_134026_9 1031288.AXAA01000008_gene1301 4.09e-05 52.8 COG3409@1|root,COG3773@1|root,COG3409@2|Bacteria,COG3773@2|Bacteria,1TRFW@1239|Firmicutes,24912@186801|Clostridia,36EDT@31979|Clostridiaceae 186801|Clostridia M Cell wall hydrolase sleB - 3.5.1.28 ko:K01449 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Hydrolase_2,PG_binding_1 k59_134026_10 1410618.JNKI01000026_gene1984 2.14e-05 54.3 COG0791@1|root,COG3409@1|root,COG0791@2|Bacteria,COG3409@2|Bacteria,1V9ZW@1239|Firmicutes,4H3PF@909932|Negativicutes 909932|Negativicutes M NlpC P60 family protein lytE - - - - - - - - - - - NLPC_P60,PG_binding_1 k59_134026_14 313612.L8106_16049 0.000296 50.4 COG3409@1|root,COG4990@1|root,COG3409@2|Bacteria,COG4990@2|Bacteria,1G4XP@1117|Cyanobacteria,1HAVP@1150|Oscillatoriales 1117|Cyanobacteria M Peptidase M15B M15C, D,D-carboxypeptidase VanY endolysins - - - - - - - - - - - - PG_binding_1,VanY k59_134026_18 1095747.HMPREF1049_1449 1.62e-16 84.3 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,378G8@32066|Fusobacteria 32066|Fusobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,HHH_5 k59_207166_4 520999.PROVALCAL_01867 3.65e-33 119.0 COG3179@1|root,COG3179@2|Bacteria,1RE8K@1224|Proteobacteria,1S4U8@1236|Gammaproteobacteria,3Z9BP@586|Providencia 1236|Gammaproteobacteria S D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Peptidase_M15_4 k59_109891_1 1165094.RINTHH_3920 2.37e-12 67.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_134097_1 1521187.JPIM01000077_gene1097 1.03e-05 55.8 COG0507@1|root,COG0507@2|Bacteria,2G626@200795|Chloroflexi,376JS@32061|Chloroflexia 32061|Chloroflexia L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 k59_12581_6 43989.cce_1126 7.06e-25 106.0 COG2856@1|root,COG3093@1|root,COG2856@2|Bacteria,COG3093@2|Bacteria,1G3K4@1117|Cyanobacteria,3KI7N@43988|Cyanothece 1117|Cyanobacteria K Pfam:DUF955 - - - ko:K18831 - - - - ko00000,ko02048,ko03000 - - - HTH_3,Peptidase_M78 k59_12581_8 1192034.CAP_1091 1.37e-25 118.0 COG0507@1|root,COG0507@2|Bacteria,1R1AT@1224|Proteobacteria,42UU6@68525|delta/epsilon subdivisions,2X85I@28221|Deltaproteobacteria 28221|Deltaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - - - - - - - - - - - k59_73491_4 1385658.U5KNR1_9VIRU 1.68e-25 107.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_73491_9 1385658.U5KPZ6_9VIRU 4.16e-119 362.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_1257_3 1430331.EP10_10445 9.51e-17 78.6 COG3405@1|root,COG3405@2|Bacteria,1VBUA@1239|Firmicutes,4HMXV@91061|Bacilli 91061|Bacilli G Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - - - - - - - - - - - k59_147135_2 269796.Rru_A3313 1.1e-77 247.0 28IR7@1|root,2Z8QR@2|Bacteria,1PBTP@1224|Proteobacteria,2U248@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_293078_1 1165094.RINTHH_3920 2.83e-65 213.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_341384_1 1234888.K0A2J2_9VIRU 8.16e-135 403.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_341384_2 1234888.K0A2R8_9VIRU 1.25e-53 183.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_341384_7 1234888.K0A2J2_9VIRU 2.6e-23 99.4 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_50013_1 1416009.V9VEH2_9CAUD 3.11e-30 123.0 4QB3X@10239|Viruses,4QWKP@35237|dsDNA viruses no RNA stage,4QPEE@28883|Caudovirales,4QNCI@10744|Podoviridae 10744|Podoviridae S VWA-like domain (DUF2201) - - - - - - - - - - - - - k59_341385_1 105154.Q9MBU6_9VIRU 1.48e-22 102.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_317402_1 242619.PG_1533 3.26e-05 53.5 COG0433@1|root,COG0433@2|Bacteria,4NFAY@976|Bacteroidetes,2FNAZ@200643|Bacteroidia,231MS@171551|Porphyromonadaceae 976|Bacteroidetes S TOPRIM - - - - - - - - - - - - AAA_25,Toprim_2 k59_329470_2 662479.C440_10628 7.07e-31 119.0 COG0338@1|root,arCOG03416@2157|Archaea,2XWJX@28890|Euryarchaeota,23VGM@183963|Halobacteria 183963|Halobacteria L D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_183162_4 926560.KE387023_gene3164 1.99e-05 52.8 COG5263@1|root,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - - - - - - - - - - - Big_2,CAP,CW_binding_1,GLTT,LRR_5,Mac-1,SLH k59_50017_1 151528.Q8W709_9CAUD 1.68e-56 200.0 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_305209_2 291603.MREP_FBNY1 2.11e-38 144.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_98550_1 344747.PM8797T_32170 5.5e-54 176.0 COG0454@1|root,COG0456@2|Bacteria,2IZ5N@203682|Planctomycetes 203682|Planctomycetes K Ribosomal-protein-alanine acetyltransferase - - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 k59_147259_1 506534.Rhein_1689 3.5e-08 60.1 COG4122@1|root,COG4122@2|Bacteria,1NKWV@1224|Proteobacteria,1SP79@1236|Gammaproteobacteria,1X22H@135613|Chromatiales 135613|Chromatiales S Methyltransferase domain - - - - - - - - - - - - Methyltransf_24 k59_62334_3 264730.PSPPH_2788 1.35e-74 240.0 COG4128@1|root,COG4128@2|Bacteria,1N0I7@1224|Proteobacteria,1SAH8@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Zonular occludens toxin (Zot) zot GO:0001906,GO:0006810,GO:0006996,GO:0007010,GO:0008150,GO:0009405,GO:0009987,GO:0016043,GO:0031640,GO:0035821,GO:0042044,GO:0042045,GO:0044364,GO:0044419,GO:0051179,GO:0051234,GO:0051704,GO:0070633,GO:0071840 - ko:K10954 ko05110,map05110 - - - ko00000,ko00001,ko02042 - - - Zot k59_293883_3 349161.Dred_2281 1.33e-24 105.0 COG0860@1|root,COG0860@2|Bacteria,1UYPW@1239|Firmicutes,24BHU@186801|Clostridia,262B5@186807|Peptococcaceae 186801|Clostridia M PFAM cell wall hydrolase autolysin - - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,CW_binding_2,SH3_3,SPOR k59_378819_2 1420600.W5RNT1_9CIRC 1.31e-21 99.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_147873_1 1120956.JHZK01000002_gene859 5.01e-14 74.7 COG3757@1|root,COG3757@2|Bacteria,1R57X@1224|Proteobacteria,2U1NJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria M M1 (1,4-beta-N-acetylmuramidase) - - - ko:K07273 - - - - ko00000 - - - Glyco_hydro_25 k59_147873_8 626522.GCWU000325_00075 1.45e-32 133.0 COG0399@1|root,COG0399@2|Bacteria,4NEBI@976|Bacteroidetes,2FPAJ@200643|Bacteroidia,1WCXS@1283313|Alloprevotella 976|Bacteroidetes M Belongs to the DegT DnrJ EryC1 family - - - - - - - - - - - - DegT_DnrJ_EryC1 k59_245124_2 509191.AEDB02000023_gene3615 1.03e-13 72.8 COG3728@1|root,COG3728@2|Bacteria,1VAD9@1239|Firmicutes,24JSU@186801|Clostridia,3WQ8E@541000|Ruminococcaceae 186801|Clostridia L Terminase small subunit - - - ko:K07474 - - - - ko00000 - - - Terminase_2 k59_172503_1 411460.RUMTOR_01348 2.3e-108 326.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_50993_1 926554.KI912617_gene4762 1.18e-47 171.0 COG1061@1|root,COG1061@2|Bacteria 2|Bacteria L Type III restriction enzyme res subunit res - - - - - - - - - - - Helicase_C,ResIII k59_27691_1 654929.REP_PCV1C 3.69e-27 112.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_88497_2 1379720.S5TNF0_9CIRC 5.83e-47 164.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_161498_1 391600.ABRU01000040_gene1824 4.34e-47 165.0 COG4422@1|root,COG4422@2|Bacteria,1MXQI@1224|Proteobacteria,2TVMB@28211|Alphaproteobacteria,2KIS7@204458|Caulobacterales 204458|Caulobacterales S Pfam:Gp37_Gp68 - - - - - - - - - - - - DUF5131 k59_319705_2 645099.MREP_BBTVA 0.000103 48.9 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_100827_2 1526550.A0A088FAP6_9VIRU 0.000105 52.0 4QAK6@10239|Viruses 10239|Viruses S N-acetylmuramoyl-L-alanine amidase activity - - - - - - - - - - - - - k59_64502_3 1234888.K0A2J2_9VIRU 2.72e-132 399.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_64502_5 1234888.K0A2R8_9VIRU 2.96e-37 138.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_149189_2 1408437.JNJN01000030_gene1055 6.32e-20 104.0 COG5283@1|root,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,2592U@186801|Clostridia,25Y6Z@186806|Eubacteriaceae 186801|Clostridia S Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_307477_1 1169161.KB897728_gene723 9.89e-11 64.7 COG3409@1|root,COG3770@1|root,COG3409@2|Bacteria,COG3770@2|Bacteria,2I94S@201174|Actinobacteria 201174|Actinobacteria M Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus - - - - - - - - - - - - PG_binding_1 k59_173661_1 1609634.A0A0C5AFV4_9VIRU 9.45e-81 261.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_100834_2 1502851.FG93_01941 9.78e-27 115.0 2DIIY@1|root,303ET@2|Bacteria,1R7AV@1224|Proteobacteria,2U40Z@28211|Alphaproteobacteria,3JXSH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_367653_1 1386089.N865_07635 4.27e-05 55.5 COG3420@1|root,COG3420@2|Bacteria,2GXES@201174|Actinobacteria,4FIUK@85021|Intrasporangiaceae 201174|Actinobacteria P Periplasmic copper-binding protein (NosD) - - - - - - - - - - - - Beta_helix k59_332915_9 871968.DESME_08930 7.39e-69 242.0 2E2CM@1|root,32XHK@2|Bacteria,1VCFP@1239|Firmicutes,24Q3M@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_368830_1 661478.OP10G_0157 2.24e-53 185.0 COG1783@1|root,COG1783@2|Bacteria 2|Bacteria S DNA packaging - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_6 k59_332916_1 2003327.CAPSD_BPCHP 3.43e-18 95.1 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_150426_8 1385658.U5KPZ6_9VIRU 8.19e-85 270.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_332922_1 1235788.C802_02967 1.18e-35 130.0 COG0270@1|root,COG0270@2|Bacteria,4NRFG@976|Bacteroidetes,2FWKI@200643|Bacteroidia 976|Bacteroidetes L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_259576_1 1262449.CP6013_3093 2.15e-06 53.9 COG1573@1|root,COG1573@2|Bacteria,1V4M9@1239|Firmicutes,24C6M@186801|Clostridia,36E51@31979|Clostridiaceae 186801|Clostridia L uracil-DNA glycosylase - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_89924_1 1692252.A0A0K1RL35_9CIRC 1.56e-76 240.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_211820_3 910314.HMPREF9220_0734 8.76e-78 266.0 COG0749@1|root,COG0749@2|Bacteria 2|Bacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_pol_A,RNase_H_2 k59_211820_5 1465639.A0A060BKV6_9CAUD 1.54e-14 77.8 4QAM2@10239|Viruses,4QV3W@35237|dsDNA viruses no RNA stage,4QPGK@28883|Caudovirales,4QNW0@10744|Podoviridae 10744|Podoviridae S exonuclease activity - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - - - - - - - - - - - k59_271973_2 1609634.A0A0C5ANA6_9VIRU 5.03e-05 50.4 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_369004_1 1288484.APCS01000031_gene2346 1.81e-20 98.2 COG5362@1|root,COG5362@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Terminase_6C k59_5054_2 608538.HTH_0543 2.77e-28 124.0 COG5362@1|root,COG5362@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Terminase_6C k59_16044_2 1536592.A0A088F894_9VIRU 5.55e-09 56.6 4QAZF@10239|Viruses 10239|Viruses S Protein of unknwon function (DUF3310) - - - - - - - - - - - - - k59_90134_1 1304275.C41B8_05368 2.06e-11 67.8 28S81@1|root,2ZEJD@2|Bacteria,1RCNN@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_273365_2 69279.BG36_03540 1e-48 172.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2TSDW@28211|Alphaproteobacteria,43K5X@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_186261_1 1151126.AQYI01000007_gene1558 9.98e-05 49.7 COG3723@1|root,COG3723@2|Bacteria,2II5R@201174|Actinobacteria,4FPDV@85023|Microbacteriaceae 201174|Actinobacteria L RecT family - - - - - - - - - - - - RecT k59_78992_1 31535.Q9XJT4_BPD3 1e-52 179.0 4QBNM@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPUI@28883|Caudovirales,4QKV6@10699|Siphoviridae 10699|Siphoviridae S Clp protease - - - - - - - - - - - - - k59_382480_3 1234888.K0A2J2_9VIRU 2.88e-23 101.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_346292_1 1692246.A0A0K1RLM8_9CIRC 1.3e-26 107.0 4QBFZ@10239|Viruses,4QUKU@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_176472_2 1219035.NT2_13_00580 3.14e-42 159.0 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_322339_1 1234888.K0A2J2_9VIRU 5.25e-100 310.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_382621_1 518766.Rmar_1022 2.71e-30 123.0 COG4653@1|root,COG4653@2|Bacteria,4NQH5@976|Bacteroidetes 976|Bacteroidetes S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_30824_1 1556290.A0A0A0RM00_9CAUD 9.36e-62 209.0 4QAXQ@10239|Viruses,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_249082_2 264203.ZMO0387 2.02e-05 51.2 28PTM@1|root,2ZCEU@2|Bacteria,1R5DD@1224|Proteobacteria,2TVG7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_115254_2 1385658.U5KNR1_9VIRU 4.64e-49 171.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_165314_1 649764.HMPREF0762_00772 1.31e-12 67.8 COG1573@1|root,COG1573@2|Bacteria,2GMPT@201174|Actinobacteria,4CUM5@84998|Coriobacteriia 84998|Coriobacteriia L Uracil-DNA glycosylase, family 4 - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_383433_1 1122226.AUHX01000014_gene520 4.14e-05 53.5 COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,1HY1D@117743|Flavobacteriia 976|Bacteroidetes L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase k59_383433_2 285514.JNWO01000072_gene10 0.000342 46.2 2A10B@1|root,30P5Q@2|Bacteria,2H2YY@201174|Actinobacteria 201174|Actinobacteria S Helix-turn-helix - - - - - - - - - - - - HTH_3 k59_31913_1 1385658.U5KPZ6_9VIRU 4.93e-91 286.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_80320_1 908340.HMPREF9406_2595 1.25e-38 145.0 COG0553@1|root,COG0553@2|Bacteria,1TP2C@1239|Firmicutes,24DVA@186801|Clostridia,36FNM@31979|Clostridiaceae 186801|Clostridia L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_359468_2 491205.JARQ01000010_gene3602 8.71e-10 55.5 2EIK5@1|root,33CBF@2|Bacteria,4NV2P@976|Bacteroidetes,1IAF5@117743|Flavobacteriia,3ZSQ6@59732|Chryseobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - k59_116512_1 1234888.K0A2J2_9VIRU 7.65e-17 89.7 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_238001_1 1009370.ALO_12301 9.78e-103 345.0 COG0553@1|root,COG0827@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,1VMRR@1239|Firmicutes,4H73C@909932|Negativicutes 909932|Negativicutes L Type III restriction enzyme, res subunit - - - - - - - - - - - - ResIII k59_226838_2 1479238.JQMZ01000001_gene2181 2.02e-14 79.3 COG5511@1|root,COG5511@2|Bacteria,1MVN4@1224|Proteobacteria,2TSGI@28211|Alphaproteobacteria 28211|Alphaproteobacteria OU Phage portal protein lambda family - - - - - - - - - - - - Phage_portal_2 k59_201951_2 1120936.KB907208_gene1066 7.16e-18 85.5 28MN1@1|root,2ZAXN@2|Bacteria,2H2TF@201174|Actinobacteria 201174|Actinobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6C k59_383617_2 7213.XP_004518328.1 1.22e-22 99.8 2CMNT@1|root,2QR3D@2759|Eukaryota,39UHX@33154|Opisthokonta,3B9U3@33208|Metazoa,3D2YM@33213|Bilateria,4201I@6656|Arthropoda,3SMSN@50557|Insecta,44Z6J@7147|Diptera 33208|Metazoa G N-acetylmuramoyl-L-alanine amidase activity. It is involved in the biological process described with peptidoglycan catabolic process PGRPLB - - ko:K01446 - - R04112 RC00064,RC00141 ko00000 - - - Amidase_2 k59_214898_2 1692244.A0A0K1RLR5_9CIRC 3.13e-80 248.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_153628_1 2003327.CAPSD_BPCHP 4.29e-17 87.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_178074_1 1121921.KB898707_gene962 1.14e-17 80.9 COG0270@1|root,COG0270@2|Bacteria,1NPQG@1224|Proteobacteria,1S07Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_262244_1 102129.Lepto7375DRAFT_0587 3.64e-11 64.3 COG5362@1|root,COG5362@2|Bacteria,1GG80@1117|Cyanobacteria,1HGUD@1150|Oscillatoriales 2|Bacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_360921_1 753085.F4YCV3_9CAUD 4.31e-30 124.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_33932_2 1123508.JH636439_gene1925 3.12e-12 70.9 2CHG1@1|root,32YZS@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_216795_1 93220.LV28_24550 9.69e-93 285.0 COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,2VP2Y@28216|Betaproteobacteria 28216|Betaproteobacteria H DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_131184_1 105154.Q9MBU6_9VIRU 8.17e-36 139.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_290550_1 1385658.U5KPZ6_9VIRU 1.28e-75 244.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_57952_1 428125.CLOLEP_01421 2.21e-25 99.0 2ARVA@1|root,31H70@2|Bacteria,1V7JT@1239|Firmicutes,24JPE@186801|Clostridia,3WP7W@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - HK97-gp10_like k59_57952_2 428125.CLOLEP_01417 8.4e-57 183.0 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia,3WMXK@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_57952_3 428125.CLOLEP_01416 2.01e-25 100.0 2ECB3@1|root,3369E@2|Bacteria,1VEV9@1239|Firmicutes,24R69@186801|Clostridia,3WNCY@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_57952_4 742740.HMPREF9474_02267 7.79e-53 174.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia,221N8@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_34065_3 1234888.K0A2J2_9VIRU 6.46e-57 193.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_385389_1 626522.GCWU000325_02069 3.41e-09 55.5 28P3F@1|root,2ZBZ4@2|Bacteria,4NMPC@976|Bacteroidetes,2FSJ3@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_144013_1 580332.Slit_1922 1.5e-54 187.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,2VM59@28216|Betaproteobacteria 28216|Betaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_119212_1 3712.Bo00285s130.1 2.55e-06 48.9 2CYIR@1|root,2S4NT@2759|Eukaryota,37W8S@33090|Viridiplantae,3GKMR@35493|Streptophyta,3I1J5@3699|Brassicales 35493|Streptophyta - - - - - - - - - - - - - - - k59_265024_3 1158150.KB906242_gene234 2.91e-43 148.0 2EMTV@1|root,33FG7@2|Bacteria 2|Bacteria S Gene 88 protein - - - - - - - - - - - - GP88 k59_218109_1 211114.JOEF01000005_gene2053 4.87e-16 82.4 COG0714@1|root,COG0714@2|Bacteria,2IDEW@201174|Actinobacteria,4EAR1@85010|Pseudonocardiales 201174|Actinobacteria O AAA domain (dynein-related subfamily) - - 6.6.1.2 ko:K09882 ko00860,ko01100,map00860,map01100 - R05227 RC02000 ko00000,ko00001,ko01000 - - - AAA_5 k59_277565_1 68170.KL590490_gene1267 2.28e-18 90.1 COG5306@1|root,COG5306@2|Bacteria 2|Bacteria - - exbB2 - - ko:K03561,ko:K12287 - - - - ko00000,ko02000,ko02044 1.A.30.2.1 - - DUF2341,Laminin_G_3,MotA_ExbB k59_189352_2 1618248.A0A0C5IB82_9CIRC 6.25e-83 259.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_10093_1 35754.JNYJ01000015_gene8535 5.45e-84 258.0 COG0451@1|root,COG0451@2|Bacteria,2IDID@201174|Actinobacteria 201174|Actinobacteria GM GDP-mannose 4,6 dehydratase - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase k59_119220_4 1340829.S5Y5F0_9CAUD 1.21e-13 77.0 4QNA2@10699|Siphoviridae 10699|Siphoviridae S AAA domain - - - - - - - - - - - - - k59_58999_1 588932.JHOF01000018_gene940 0.00042 46.2 COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,2TQTD@28211|Alphaproteobacteria,2KIXW@204458|Caulobacterales 204458|Caulobacterales M Transglycosylase SLT domain - - - - - - - - - - - - SLT k59_314354_1 1415775.U729_3168 3.2e-19 82.8 2A5EH@1|root,30U4B@2|Bacteria,1UTI8@1239|Firmicutes,2534V@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_278750_4 665571.STHERM_c13180 1.95e-14 72.8 COG0629@1|root,COG0629@2|Bacteria,2J7A3@203691|Spirochaetes 203691|Spirochaetes L Single-stranded DNA-binding protein - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_278750_5 1218352.B597_019615 2.15e-52 171.0 2E5K5@1|root,330BC@2|Bacteria,1RG8X@1224|Proteobacteria,1S3Z1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Siphovirus Gp157 - - - - - - - - - - - - Sipho_Gp157 k59_278750_6 420662.Mpe_B0362 1.06e-50 173.0 COG3206@1|root,COG3206@2|Bacteria,1ND5H@1224|Proteobacteria,2W2TN@28216|Betaproteobacteria 28216|Betaproteobacteria M protein involved in exopolysaccharide biosynthesis - - - - - - - - - - - - - k59_169488_1 1420600.W5RNT1_9CIRC 8.52e-30 121.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_48326_1 48698.ENSPFOP00000001570 0.000328 47.0 KOG1565@1|root,KOG1565@2759|Eukaryota,39SEW@33154|Opisthokonta,3B9DD@33208|Metazoa,3CVA2@33213|Bilateria,488CT@7711|Chordata,48ZJM@7742|Vertebrata,4A1JX@7898|Actinopterygii 33208|Metazoa OW Belongs to the peptidase M10A family MMP9 GO:0000003,GO:0000302,GO:0001101,GO:0001501,GO:0001503,GO:0001655,GO:0001666,GO:0001704,GO:0001706,GO:0001775,GO:0001822,GO:0001932,GO:0001934,GO:0001968,GO:0002237,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002520,GO:0002521,GO:0002573,GO:0002682,GO:0002684,GO:0002685,GO:0002687,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0004252,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0006810,GO:0006887,GO:0006950,GO:0006955,GO:0006979,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007369,GO:0007492,GO:0007507,GO:0007565,GO:0007566,GO:0007567,GO:0007568,GO:0007584,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008237,GO:0008270,GO:0008284,GO:0008285,GO:0009056,GO:0009266,GO:0009314,GO:0009408,GO:0009416,GO:0009605,GO:0009607,GO:0009612,GO:0009617,GO:0009628,GO:0009636,GO:0009642,GO:0009644,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009888,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0010243,GO:0010466,GO:0010562,GO:0010604,GO:0010605,GO:0010632,GO:0010634,GO:0010638,GO:0010646,GO:0010647,GO:0010648,GO:0010821,GO:0010822,GO:0010941,GO:0010942,GO:0010951,GO:0012505,GO:0014070,GO:0016032,GO:0016043,GO:0016192,GO:0016787,GO:0017171,GO:0019048,GO:0019087,GO:0019220,GO:0019221,GO:0019222,GO:0019538,GO:0022411,GO:0022414,GO:0022603,GO:0022607,GO:0022617,GO:0022898,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030097,GO:0030099,GO:0030141,GO:0030154,GO:0030162,GO:0030198,GO:0030225,GO:0030334,GO:0030335,GO:0030574,GO:0031323,GO:0031324,GO:0031325,GO:0031399,GO:0031401,GO:0031410,GO:0031667,GO:0031668,GO:0031915,GO:0031974,GO:0031982,GO:0032092,GO:0032268,GO:0032269,GO:0032270,GO:0032355,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032496,GO:0032501,GO:0032502,GO:0032526,GO:0032879,GO:0032940,GO:0032963,GO:0032991,GO:0033043,GO:0033189,GO:0033273,GO:0033554,GO:0033993,GO:0034097,GO:0034599,GO:0034612,GO:0034614,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0035094,GO:0035821,GO:0035987,GO:0036230,GO:0036293,GO:0036296,GO:0040012,GO:0040017,GO:0042058,GO:0042119,GO:0042127,GO:0042221,GO:0042325,GO:0042327,GO:0042493,GO:0042802,GO:0042981,GO:0043062,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043086,GO:0043154,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0043269,GO:0043271,GO:0043281,GO:0043299,GO:0043312,GO:0043388,GO:0043393,GO:0043933,GO:0044003,GO:0044085,GO:0044092,GO:0044093,GO:0044238,GO:0044403,GO:0044419,GO:0044421,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0044877,GO:0045055,GO:0045321,GO:0045471,GO:0045742,GO:0045765,GO:0045766,GO:0045861,GO:0045937,GO:0046677,GO:0046686,GO:0046872,GO:0046903,GO:0046914,GO:0048013,GO:0048145,GO:0048147,GO:0048167,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048583,GO:0048584,GO:0048585,GO:0048598,GO:0048646,GO:0048660,GO:0048661,GO:0048731,GO:0048771,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050804,GO:0050896,GO:0051049,GO:0051051,GO:0051094,GO:0051098,GO:0051099,GO:0051101,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051248,GO:0051259,GO:0051270,GO:0051272,GO:0051336,GO:0051346,GO:0051547,GO:0051549,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051817,GO:0052547,GO:0052548,GO:0055093,GO:0055094,GO:0060255,GO:0060548,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070011,GO:0070013,GO:0070482,GO:0070555,GO:0070820,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071241,GO:0071248,GO:0071276,GO:0071281,GO:0071283,GO:0071310,GO:0071345,GO:0071347,GO:0071356,GO:0071396,GO:0071402,GO:0071404,GO:0071460,GO:0071496,GO:0071704,GO:0071840,GO:0072001,GO:0072359,GO:0080090,GO:0090199,GO:0090200,GO:0097305,GO:0097708,GO:0099177,GO:0099503,GO:0101002,GO:0140096,GO:1900120,GO:1900122,GO:1901184,GO:1901186,GO:1901342,GO:1901564,GO:1901698,GO:1901700,GO:1901701,GO:1902531,GO:1902532,GO:1904018,GO:1904062,GO:1904063,GO:1904705,GO:1904707,GO:1904724,GO:1904813,GO:2000026,GO:2000116,GO:2000117,GO:2000145,GO:2000147,GO:2001233,GO:2001234,GO:2001235,GO:2001242,GO:2001243,GO:2001257,GO:2001258,GO:2001267,GO:2001268 3.4.24.35 ko:K01403 ko01522,ko04657,ko04668,ko04670,ko04915,ko04926,ko05161,ko05200,ko05202,ko05205,ko05206,ko05215,ko05219,ko05418,map01522,map04657,map04668,map04670,map04915,map04926,map05161,map05200,map05202,map05205,map05206,map05215,map05219,map05418 - - - ko00000,ko00001,ko01000,ko01002 - - - Hemopexin,PG_binding_1,PT,Peptidase_M10,fn2 k59_242450_2 115711.CP_0543 2.2e-23 95.9 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_266337_1 1234888.K0A2J2_9VIRU 3.24e-106 327.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_266337_6 186617.M9M8L2_9VIRU 1.57e-13 74.7 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_109075_1 1609634.A0A0C5AFV4_9VIRU 2.95e-46 164.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_109075_4 1165094.RINTHH_3920 8.65e-63 208.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_120629_1 1402135.SUH3_12045 4.16e-13 72.8 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2U8JK@28211|Alphaproteobacteria,3ZWVW@60136|Sulfitobacter 28211|Alphaproteobacteria G Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_120629_4 948071.S4S2D9_9CAUD 1.34e-78 254.0 4QAXQ@10239|Viruses,4QUSY@35237|dsDNA viruses no RNA stage,4QRFY@28883|Caudovirales,4QNQ6@10744|Podoviridae 10744|Podoviridae S ribonucleoside-triphosphate reductase activity - - - - - - - - - - - - - k59_254703_3 49964.Q94MR7_9CAUD 1.09e-93 303.0 4QERB@10239|Viruses,4R014@35237|dsDNA viruses no RNA stage,4QTGJ@28883|Caudovirales,4QNZG@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_363514_1 1234888.K0A2R8_9VIRU 2.57e-14 78.2 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_254928_1 1385658.U5KPZ6_9VIRU 1.04e-96 301.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_376388_2 1121946.AUAX01000011_gene3986 2.06e-49 163.0 COG2856@1|root,COG2856@2|Bacteria,2IFC9@201174|Actinobacteria,4DDDK@85008|Micromonosporales 201174|Actinobacteria E Zn peptidase - - - - - - - - - - - - Macro k59_376388_3 118163.Ple7327_1384 0.000856 47.8 COG1216@1|root,COG1216@2|Bacteria,1G5CI@1117|Cyanobacteria,3VNMM@52604|Pleurocapsales 1117|Cyanobacteria S Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 k59_376388_4 558152.IQ37_06585 3.53e-42 154.0 COG0451@1|root,COG0451@2|Bacteria 2|Bacteria GM ADP-glyceromanno-heptose 6-epimerase activity - - 5.1.3.2,5.1.3.6 ko:K01784,ko:K08679 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R01385,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd k59_206771_5 1121378.KB899701_gene2047 5.22e-13 77.4 COG3378@1|root,COG5519@1|root,COG3378@2|Bacteria,COG5519@2|Bacteria 2|Bacteria KL Phage plasmid primase P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N,DUF3854,DUF927,Pox_D5,Prim-Pol,RepB_primase,Toprim_3 k59_206771_7 1146883.BLASA_2675 1.26e-10 63.5 2EFG7@1|root,3398W@2|Bacteria,2ID0P@201174|Actinobacteria 201174|Actinobacteria L Recombination endonuclease VII - - - - - - - - - - - - Endonuclease_7 k59_206771_9 565045.NOR51B_489 8.52e-41 152.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1J4Z9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_146009_2 1609634.A0A0C5AFV4_9VIRU 1.67e-173 507.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_328266_1 1609634.A0A0C5AFT2_9VIRU 8.21e-77 244.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_36705_1 105154.Q9MBU0_9VIRU 7.35e-42 150.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_36705_6 1385658.U5KPZ6_9VIRU 6.99e-158 462.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_267379_2 866776.HMPREF9321_0468 9.07e-25 108.0 COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,4H26C@909932|Negativicutes 909932|Negativicutes M NAD dependent epimerase dehydratase family protein - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase k59_218978_1 1122201.AUAZ01000017_gene2960 1.15e-94 291.0 COG5362@1|root,COG5362@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Terminase_6C k59_121763_1 35128.Thaps263033 1.74e-10 70.9 COG0749@1|root,KOG0950@2759|Eukaryota 2759|Eukaryota L plastid DNA replication POL1A - 2.7.7.7 ko:K02335,ko:K02349 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DEAD,DNA_pol_A,Helicase_C k59_279792_4 1234888.K0A2J2_9VIRU 5.31e-140 419.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_206811_1 1385658.U5KPZ6_9VIRU 3.32e-164 483.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_206811_2 105154.Q9MBU3_9VIRU 6.57e-12 70.1 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_206811_4 1165094.RINTHH_3920 1.11e-62 207.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_85311_1 866536.Belba_0317 3.54e-17 84.7 COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,47MQV@768503|Cytophagia 976|Bacteroidetes M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose rfbD - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind k59_73147_1 1095749.HMPREF1052_0847 1.02e-15 89.4 COG5283@1|root,COG5283@2|Bacteria,1NFKU@1224|Proteobacteria,1RP2D@1236|Gammaproteobacteria,1Y6YZ@135625|Pasteurellales 135625|Pasteurellales S Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_36962_3 926549.KI421517_gene4159 1.62e-42 174.0 COG1196@1|root,COG1196@2|Bacteria,4PP9M@976|Bacteroidetes 976|Bacteroidetes D nuclear chromosome segregation - - - - - - - - - - - - - k59_231325_1 1042209.HK44_029960 4.23e-53 199.0 2D1GK@1|root,32TAP@2|Bacteria,1QV4T@1224|Proteobacteria,1SKJY@1236|Gammaproteobacteria 1236|Gammaproteobacteria L C-5 cytosine-specific DNA methylase - - - - - - - - - - - - DNA_methylase k59_280103_1 226185.EF_2307 6.14e-114 375.0 COG0249@1|root,COG0553@1|root,COG0827@1|root,COG3170@1|root,COG4646@1|root,COG0249@2|Bacteria,COG0553@2|Bacteria,COG0827@2|Bacteria,COG3170@2|Bacteria,COG4646@2|Bacteria,1TPQA@1239|Firmicutes,4I385@91061|Bacilli,4B10R@81852|Enterococcaceae 91061|Bacilli KL SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_316439_1 1366050.N234_18785 1.59e-11 67.8 2D0K9@1|root,32T8S@2|Bacteria,1MZRW@1224|Proteobacteria,2VW7X@28216|Betaproteobacteria,1KE19@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_364934_2 1234888.K0A2J2_9VIRU 1.19e-117 358.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_207231_1 221538.REP_TYCS2 1.57e-09 60.8 4QB6C@10239|Viruses,4QUKM@29258|ssDNA viruses 10239|Viruses J Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_255592_1 575540.Isop_2448 3.09e-15 73.9 COG3613@1|root,COG3613@2|Bacteria 2|Bacteria F nucleoside 2-deoxyribosyltransferase - - - - - - - - - - - - DUF1937 k59_170483_2 1265505.ATUG01000001_gene4770 0.000189 47.0 COG0727@1|root,COG0727@2|Bacteria,1N683@1224|Proteobacteria,42TJ1@68525|delta/epsilon subdivisions,2WQ91@28221|Deltaproteobacteria,2MKF6@213118|Desulfobacterales 28221|Deltaproteobacteria S Putative zinc- or iron-chelating domain - - - - - - - - - - - - CxxCxxCC k59_353010_1 323097.Nham_3219 1.51e-23 101.0 COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,2TT4Q@28211|Alphaproteobacteria,3JU3F@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L UreE urease accessory protein, C-terminal domain udgA - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_353010_2 1231190.NA8A_19588 8.05e-14 69.3 COG0863@1|root,COG0863@2|Bacteria,1R7KV@1224|Proteobacteria,2U3KV@28211|Alphaproteobacteria,43Q9K@69277|Phyllobacteriaceae 28211|Alphaproteobacteria L DNA methylase - - 2.1.1.72 ko:K00571,ko:K07319 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_328671_1 1121921.KB898707_gene986 2.06e-12 73.2 COG4733@1|root,COG4733@2|Bacteria,1NCQ4@1224|Proteobacteria,1SEXE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S cellulase activity - - - - - - - - - - - - DUF1983,DUF3672 k59_122067_1 1609634.A0A0C5AFV4_9VIRU 2.1e-35 132.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_122067_3 1609634.A0A0C5AFT2_9VIRU 8.39e-86 265.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_207237_1 1279017.AQYJ01000028_gene2239 2.92e-18 89.7 COG4675@1|root,COG4675@2|Bacteria,1RESM@1224|Proteobacteria,1S7DU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S tail collar domain protein - - - - - - - - - - - - DUF3751 k59_195061_5 13035.Dacsa_0972 4.63e-09 69.3 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1G1P1@1117|Cyanobacteria 1117|Cyanobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_219415_1 1385658.U5KPZ6_9VIRU 1.76e-72 239.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_170486_1 582744.Msip34_2836 1.9e-49 175.0 COG0464@1|root,COG0464@2|Bacteria,1QU82@1224|Proteobacteria,2WHSD@28216|Betaproteobacteria,2KNN6@206350|Nitrosomonadales 206350|Nitrosomonadales O Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_353927_5 1234888.K0A2J2_9VIRU 7.66e-112 344.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_134864_1 979535.F1D014_9CAUD 2.89e-12 70.1 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QNBW@10744|Podoviridae 10744|Podoviridae S DNA helicase activity - - - - - - - - - - - - - k59_353931_1 1203632.HMPREF1300_01527 2.34e-12 67.8 COG0791@1|root,COG0791@2|Bacteria,2GKHE@201174|Actinobacteria,22JIX@1653|Corynebacteriaceae 201174|Actinobacteria DM Cell wall-associated hydrolases rpfI GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0008150,GO:0008745,GO:0016787,GO:0016810,GO:0016811,GO:0030312,GO:0040007,GO:0044464,GO:0061783,GO:0071944 - ko:K21473,ko:K21474 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60 k59_220344_1 260827.Q6R6B4_9CAUD 6.83e-75 244.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales,4QNDH@10744|Podoviridae 10744|Podoviridae S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_256515_1 1123501.KB902299_gene3814 1.44e-13 70.9 COG3108@1|root,COG3108@2|Bacteria,1QDAN@1224|Proteobacteria,2TV1K@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Bacterial protein of unknown function (DUF882) - - - - - - - - - - - - Peptidase_M15_3 k59_256515_6 1366046.HIMB11_03039 8.18e-08 53.5 COG3108@1|root,COG3108@2|Bacteria,1NEFB@1224|Proteobacteria,2UI1R@28211|Alphaproteobacteria,3ZIGX@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria S Bacterial protein of unknown function (DUF882) - - - - - - - - - - - - Peptidase_M15_2 k59_329497_2 665956.HMPREF1032_02700 1.86e-12 66.6 COG4675@1|root,COG4675@2|Bacteria,1VICV@1239|Firmicutes 1239|Firmicutes S PFAM Tail Collar domain protein - - - - - - - - - - - - Collar k59_268680_2 145579.CAPSD_BPPHM 8.23e-25 107.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_208107_1 1453496.AT03_13345 3.06e-12 63.5 COG4570@1|root,COG4570@2|Bacteria,1N92D@1224|Proteobacteria,1S738@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC - - 3.1.22.4 ko:K01160 - - - - ko00000,ko01000,ko03400 - - - RusA k59_365661_7 202954.BBNK01000010_gene1458 3.36e-19 84.0 2AJ1X@1|root,319K5@2|Bacteria,1RK0X@1224|Proteobacteria,1SG38@1236|Gammaproteobacteria,3NPGD@468|Moraxellaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2829) - - - - - - - - - - - - DUF2829 k59_171457_1 1121448.DGI_2307 1.05e-07 59.3 COG0859@1|root,COG0859@2|Bacteria,1NABN@1224|Proteobacteria,42V15@68525|delta/epsilon subdivisions,2WRJN@28221|Deltaproteobacteria,2MA6E@213115|Desulfovibrionales 28221|Deltaproteobacteria M PFAM glycosyl transferase family 9 - - - - - - - - - - - - Glyco_transf_9 k59_171457_3 1122931.AUAE01000011_gene1861 2.69e-07 57.4 COG0582@1|root,COG0582@2|Bacteria,4NDZJ@976|Bacteroidetes,2FQM2@200643|Bacteroidia,2302J@171551|Porphyromonadaceae 976|Bacteroidetes L Arm DNA-binding domain - - - - - - - - - - - - Arm-DNA-bind_5,Phage_int_SAM_5,Phage_integrase k59_244191_2 1041147.AUFB01000014_gene329 3.17e-37 136.0 2CXZV@1|root,32T32@2|Bacteria,1N4R9@1224|Proteobacteria,2UM96@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_353938_1 1123314.AUIO01000005_gene168 5.17e-10 69.3 28MKK@1|root,2ZAWR@2|Bacteria,1UYAT@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_86467_2 1423144.Gal_02240 1.82e-60 192.0 COG3023@1|root,COG3023@2|Bacteria,1ND21@1224|Proteobacteria,2UGIR@28211|Alphaproteobacteria 28211|Alphaproteobacteria V T7 lysozyme hydrolyzes an amide bond in the host cell wall following its release from the cytoplasm. In addition, T7 lysozyme inhibits T7 RNA polymerase initiation. This inhibition is greater for class II promoters than class III promoters and therefore may aid in temporal regulation of transcription and the switch to particle assembly. In T7, lysozyme, unlike the T7 holin, is expressed with and lies in the same region as the replication genes. Lack of gp3.5 reduces replication and burst size and delays, but does not completely prevent lysis. Mutations in the muralytic domain of gene 16, an inner capsid protein, can partially compensate for a deletion of gp3.5. Other names gp3.5 - - - - - - - - - - - - Amidase_2 k59_171593_1 1094496.m07a_07920 1.28e-28 112.0 COG1044@1|root,COG1044@2|Bacteria,1NBEI@1224|Proteobacteria,2TZFU@28211|Alphaproteobacteria,48URD@772|Bartonellaceae 28211|Alphaproteobacteria M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - - - - - - - - - - - k59_196949_1 1121459.AQXE01000001_gene2737 3.1e-91 273.0 2EMTV@1|root,33FG7@2|Bacteria 2|Bacteria S Gene 88 protein - - - - - - - - - - - - GP88 k59_160508_1 1166948.JPZL01000002_gene1842 2.4e-58 206.0 28P6A@1|root,2ZC10@2|Bacteria,1RBZE@1224|Proteobacteria,1RRNS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_172543_1 1165094.RINTHH_3920 4.68e-36 132.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_124205_3 1429794.A0A0A0Q0K7_9CAUD 6.28e-25 108.0 4QCM7@10239|Viruses,4QVN1@35237|dsDNA viruses no RNA stage,4QPQ5@28883|Caudovirales,4QIHM@10662|Myoviridae 10662|Myoviridae S RNA ligase - - - - - - - - - - - - - k59_63435_1 1609634.A0A0C5AFT2_9VIRU 4.03e-22 100.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_38636_4 648996.Theam_0802 7.77e-20 95.9 COG1087@1|root,COG1087@2|Bacteria 2|Bacteria M UDP-glucose 4-epimerase activity galE - 5.1.3.2,5.1.3.25 ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 M00361,M00362,M00632 R00291,R02984,R10279 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd k59_38636_5 883080.HMPREF9697_00268 1.12e-07 56.6 COG0438@1|root,COG0438@2|Bacteria,1R1XI@1224|Proteobacteria,2TZ6P@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 k59_257618_2 272556.CF65_00531 2.96e-18 97.8 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1Y7ZN@135625|Pasteurellales 135625|Pasteurellales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_306365_1 1692257.A0A0K1RL39_9CIRC 7.17e-102 307.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_75367_2 1121382.JQKG01000001_gene2498 0.000409 47.4 2E2AR@1|root,32XG5@2|Bacteria 2|Bacteria S PFAM Pathogenesis-related transcriptional factor and ERF - - - - - - - - - - - - AP2,HNH_3 k59_172664_2 408672.NBCG_01024 5.73e-16 89.4 COG0739@1|root,COG3568@1|root,COG0739@2|Bacteria,COG3568@2|Bacteria,2GKXN@201174|Actinobacteria,4DRKF@85009|Propionibacteriales 201174|Actinobacteria M Peptidase family M23 - - - - - - - - - - - - Exo_endo_phos,Peptidase_M23 k59_26780_1 375286.mma_2192 7.29e-30 127.0 2ES6Y@1|root,33JRQ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_111785_1 438753.AZC_3597 2.02e-122 369.0 COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,2TVEI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L DNA polymerase family A - - - - - - - - - - - - DNA_pol_A k59_87596_1 105154.Q9MBU0_9VIRU 2.88e-66 215.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_331868_1 105154.Q9MBU3_9VIRU 6.71e-09 60.5 4QCV4@10239|Viruses,4QUKY@29258|ssDNA viruses,4QP4B@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_137052_1 1382356.JQMP01000001_gene954 2.26e-26 121.0 COG3598@1|root,COG3598@2|Bacteria,2G9MF@200795|Chloroflexi 200795|Chloroflexi L AAA domain - - - - - - - - - - - - AAA_25 k59_307513_12 344747.PM8797T_14906 1.41e-89 280.0 COG2165@1|root,COG2165@2|Bacteria,2IXWM@203682|Planctomycetes 203682|Planctomycetes NU Pfam:N_methyl_2 - - - - - - - - - - - - N_methyl,SBP_bac_10 k59_112818_1 1555208.A0A097EW10_9CAUD 0.000561 48.1 4QC60@10239|Viruses,4QPPD@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_3824_1 1618248.A0A0C5IB82_9CIRC 1.31e-23 101.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_76392_1 526222.Desal_1444 0.00021 52.8 2DNU8@1|root,32Z5M@2|Bacteria,1NARQ@1224|Proteobacteria,432SD@68525|delta/epsilon subdivisions,2WY7K@28221|Deltaproteobacteria,2MD12@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_355950_4 1219031.BBJR01000049_gene1548 4.02e-23 96.7 COG3756@1|root,COG3756@2|Bacteria,1QUEM@1224|Proteobacteria,2WHQP@28216|Betaproteobacteria,4AIKF@80864|Comamonadaceae 28216|Betaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - - k59_234463_1 1609634.A0A0C5AFV4_9VIRU 4.51e-84 269.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_112824_1 189425.PGRAT_28930 2.96e-06 54.3 2F5GB@1|root,33Y1Y@2|Bacteria,1VWA9@1239|Firmicutes,4ISQ2@91061|Bacilli,2776D@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - k59_173748_3 765912.Thimo_1718 1.23e-42 141.0 COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,1SCYV@1236|Gammaproteobacteria,1WYTT@135613|Chromatiales 135613|Chromatiales K TIGRFAM Addiction module antidote protein, HigA - - - ko:K21498 - - - - ko00000,ko02048 - - - HTH_3 k59_173748_6 1485545.JQLW01000010_gene1515 7.07e-52 166.0 COG4737@1|root,COG4737@2|Bacteria,1N7N5@1224|Proteobacteria 1224|Proteobacteria K Cytotoxic translational repressor of toxin-antitoxin stability system relE - - - - - - - - - - - RelE k59_173748_7 754476.Q7A_921 1.19e-49 159.0 COG2944@1|root,COG2944@2|Bacteria,1MZGM@1224|Proteobacteria,1SB1E@1236|Gammaproteobacteria,461HY@72273|Thiotrichales 72273|Thiotrichales K Helix-turn-helix XRE-family like proteins - - - ko:K07726 - - - - ko00000,ko03000 - - - - k59_149325_1 272630.MexAM1_META1p3965 5.76e-10 65.1 COG1475@1|root,COG1475@2|Bacteria 2|Bacteria K chromosome segregation - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_125429_2 1230476.C207_01166 1.56e-25 103.0 28PTM@1|root,2ZCEU@2|Bacteria,1R5DD@1224|Proteobacteria,2TVG7@28211|Alphaproteobacteria,3JU4C@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_234471_1 78245.Xaut_3158 2.75e-13 73.2 2CK39@1|root,32SBG@2|Bacteria,1MZ6F@1224|Proteobacteria,2UBT5@28211|Alphaproteobacteria,3EZQI@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 k59_210598_1 509191.AEDB02000023_gene3615 8.41e-20 88.6 COG3728@1|root,COG3728@2|Bacteria,1VAD9@1239|Firmicutes,24JSU@186801|Clostridia,3WQ8E@541000|Ruminococcaceae 186801|Clostridia L Terminase small subunit - - - ko:K07474 - - - - ko00000 - - - Terminase_2 k59_210598_2 1341151.ASZU01000008_gene1531 2.37e-79 258.0 COG1783@1|root,COG1783@2|Bacteria,1VK0H@1239|Firmicutes,4HQ2H@91061|Bacilli 91061|Bacilli S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_272025_3 1051675.G0YQF5_9CAUD 8.74e-17 81.3 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_235573_1 1123020.AUIE01000007_gene3222 4.23e-75 248.0 COG1196@1|root,COG2911@1|root,COG1196@2|Bacteria,COG2911@2|Bacteria,1NJBY@1224|Proteobacteria,1S2RC@1236|Gammaproteobacteria 1236|Gammaproteobacteria D Protein conserved in bacteria - - - - - - - - - - - - - k59_235573_2 1354303.M917_2294 6.47e-14 67.8 2DQXX@1|root,339A9@2|Bacteria,1NBJ3@1224|Proteobacteria,1SRKE@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_212020_1 411460.RUMTOR_01335 1.17e-207 652.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_212020_2 478749.BRYFOR_08514 1.35e-41 141.0 2ARVA@1|root,31H70@2|Bacteria,1V7JT@1239|Firmicutes,24JPE@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - HK97-gp10_like k59_212020_3 742733.HMPREF9469_05023 2.83e-61 195.0 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia,222RY@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_212020_5 742740.HMPREF9474_02267 3.31e-86 261.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia,221N8@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_212020_8 691965.D4P7D6_9CAUD 4.35e-164 492.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_16101_2 570967.JMLV01000018_gene466 1.99e-22 92.4 COG0741@1|root,COG0741@2|Bacteria,1N1XZ@1224|Proteobacteria,2UB2Y@28211|Alphaproteobacteria,2JWX1@204441|Rhodospirillales 204441|Rhodospirillales M Transglycosylase SLT domain - - - - - - - - - - - - SLT k59_113952_2 1609634.A0A0C5ANA6_9VIRU 1.87e-15 80.5 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_77778_1 335283.Neut_1455 7.73e-65 225.0 COG2304@1|root,COG4733@1|root,COG2304@2|Bacteria,COG4733@2|Bacteria,1MXB4@1224|Proteobacteria,2VJS7@28216|Betaproteobacteria 28216|Betaproteobacteria M Putative phage tail protein - - - - - - - - - - - - Phage-tail_3 k59_113956_1 1385658.U5KPZ6_9VIRU 3.21e-58 196.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_175377_1 1161935.H9D1D6_9CAUD 3.99e-42 148.0 4QFN8@10239|Viruses,4QYWE@35237|dsDNA viruses no RNA stage,4QS52@28883|Caudovirales,4QP1K@10744|Podoviridae 10744|Podoviridae S metal ion binding - - - - - - - - - - - - - k59_90323_1 1089549.AZUQ01000001_gene2987 2.4e-17 81.6 COG0237@1|root,COG0237@2|Bacteria,2ISY6@201174|Actinobacteria 201174|Actinobacteria H dephospho-CoA kinase activity - - - - - - - - - - - - - k59_381630_1 691965.D4P7I3_9CAUD 4.78e-43 160.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_296708_2 926692.AZYG01000059_gene78 1.23e-06 57.8 COG3935@1|root,COG3935@2|Bacteria,1UFH2@1239|Firmicutes,25KUA@186801|Clostridia,3WC5Z@53433|Halanaerobiales 186801|Clostridia L DnaD domain protein - - - - - - - - - - - - - k59_247908_1 2754.EH55_01380 3.28e-11 72.4 2DBPZ@1|root,2ZABJ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_200707_1 1385658.U5KPZ6_9VIRU 3.63e-25 106.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_128086_4 756272.Plabr_0991 3.39e-20 86.3 COG0137@1|root,COG0137@2|Bacteria 2|Bacteria E argininosuccinate synthase activity argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - iJN678.argG,iSB619.SA_RS04675 Arginosuc_synth k59_346654_2 935848.JAEN01000019_gene2011 1.36e-06 54.7 COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,2TVB3@28211|Alphaproteobacteria,2PYSH@265|Paracoccus 28211|Alphaproteobacteria S Phage tail sheath C-terminal domain - - - ko:K06907 - - - - ko00000 - - - Phage_sheath_1,Phage_sheath_1C k59_103641_1 691965.D4P7D6_9CAUD 4.95e-69 231.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_42738_3 595536.ADVE02000001_gene3180 1.51e-10 71.6 COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2TV2W@28211|Alphaproteobacteria,36XJ8@31993|Methylocystaceae 28211|Alphaproteobacteria S COG4733 Phage-related protein, tail component - - - - - - - - - - - - Phage-tail_3 k59_103642_1 1094558.ME5_00025 6.97e-10 62.0 2DIG9@1|root,3036R@2|Bacteria,1R0G3@1224|Proteobacteria,2TZFY@28211|Alphaproteobacteria 28211|Alphaproteobacteria L YqaJ-like viral recombinase domain - - - - - - - - - - - - YqaJ k59_42746_1 1121382.JQKG01000015_gene1713 1.88e-21 98.2 COG5362@1|root,COG5362@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Terminase_6C k59_322735_2 46234.ANA_C12634 1.19e-09 65.1 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_trans_1_4,Glycos_transf_1,Sulfotransfer_2 k59_17413_5 362976.HQ_1364A 2.24e-27 122.0 COG0210@1|root,arCOG00797@2157|Archaea,2XUH7@28890|Euryarchaeota,23S3W@183963|Halobacteria 183963|Halobacteria L COG0210 Superfamily I DNA and RNA helicases uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k59_67363_1 156889.Mmc1_1014 2.29e-13 73.9 2C22H@1|root,332AB@2|Bacteria,1NBGI@1224|Proteobacteria,2UFBV@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - Peptidase_S74 k59_213685_3 290315.Clim_2149 3.38e-16 77.4 COG0629@1|root,COG0629@2|Bacteria,1FE0M@1090|Chlorobi 1090|Chlorobi L PFAM single-strand binding protein Primosomal replication protein n - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_104959_2 1379709.S5TMV0_9CIRC 1.87e-39 146.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_187353_1 1157632.AQWQ01000001_gene5726 1.33e-18 89.4 COG0553@1|root,COG0553@2|Bacteria,2GISC@201174|Actinobacteria 201174|Actinobacteria L helicase - - - - - - - - - - - - HHH_5,Helicase_C,SNF2_N k59_68879_1 1385658.U5KPZ6_9VIRU 7.12e-114 351.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_300082_1 1088721.NSU_0323 5.9e-55 189.0 COG5362@1|root,COG5362@2|Bacteria,1NKZK@1224|Proteobacteria,2U4BJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_227114_9 35703.DQ02_13760 1.31e-21 90.9 COG4570@1|root,COG4570@2|Bacteria,1RH5J@1224|Proteobacteria,1S7I6@1236|Gammaproteobacteria 1236|Gammaproteobacteria L endodeoxyribonuclease RusA - - - - - - - - - - - - RusA k59_44160_2 33898.JRHJ01000076_gene413 8.22e-25 113.0 COG1783@1|root,COG1783@2|Bacteria,2I8SC@201174|Actinobacteria 201174|Actinobacteria S Terminase-like family - - - - - - - - - - - - Terminase_3,Terminase_6,Terminase_6C k59_300088_1 1322246.BN4_20100 7.97e-110 330.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,42QA8@68525|delta/epsilon subdivisions,2WJBW@28221|Deltaproteobacteria,2M8NS@213115|Desulfovibrionales 28221|Deltaproteobacteria S PFAM ATPase associated with various cellular activities - - - - - - - - - - - - AAA_3,AAA_5 k59_289143_1 571166.KI421509_gene1199 2.37e-25 111.0 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,2TUXC@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Type III restriction enzyme res subunit - - - ko:K19789 - - - - ko00000,ko03400 - - - DUF3427,HIT,Helicase_C,PLDc_2,ResIII,UPF0547 k59_348437_5 665956.HMPREF1032_00674 2.45e-89 282.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia,3WNJZ@541000|Ruminococcaceae 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_8004_1 1380391.JIAS01000005_gene2445 7.64e-08 61.2 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,2TT3N@28211|Alphaproteobacteria,2JQ8P@204441|Rhodospirillales 204441|Rhodospirillales S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_8004_3 1123355.JHYO01000035_gene588 3.62e-06 55.1 28Q3Q@1|root,2ZCM8@2|Bacteria,1RA4F@1224|Proteobacteria,2U6B5@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_8004_5 1089552.KI911559_gene3374 5.35e-98 295.0 28HS3@1|root,2Z7ZE@2|Bacteria,1QH9A@1224|Proteobacteria,2TVB0@28211|Alphaproteobacteria,2JPPD@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_8004_8 1121033.AUCF01000015_gene1505 6.35e-19 90.1 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,2TVGJ@28211|Alphaproteobacteria,2JPR0@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_250942_2 1278307.KB907051_gene2631 3.73e-25 100.0 COG3409@1|root,COG3409@2|Bacteria,1R4RS@1224|Proteobacteria,1S346@1236|Gammaproteobacteria 1236|Gammaproteobacteria M CHAP domain - - - - - - - - - - - - CHAP k59_359924_2 1283077.M1HLI2_9CAUD 1.14e-99 325.0 4QC24@10239|Viruses,4QZPR@35237|dsDNA viruses no RNA stage,4QRZK@28883|Caudovirales,4QP0N@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_93847_3 312309.VF_A0917 2.05e-11 62.8 COG2131@1|root,COG2131@2|Bacteria,1RD1P@1224|Proteobacteria,1SFR6@1236|Gammaproteobacteria,1Y2XU@135623|Vibrionales 135623|Vibrionales F MafB19-like deaminase - - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 k59_227301_1 1346791.M529_10465 2.89e-05 51.2 COG3409@1|root,COG3409@2|Bacteria,1REI1@1224|Proteobacteria,2U734@28211|Alphaproteobacteria,2K4CS@204457|Sphingomonadales 204457|Sphingomonadales M Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_1 k59_264076_1 665950.HMPREF1025_01957 1.27e-52 188.0 2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_167191_1 1472912.A0A023NGT1_9CAUD 1.56e-79 259.0 4QAW1@10239|Viruses,4QWUW@35237|dsDNA viruses no RNA stage,4QR8A@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_143190_2 742733.HMPREF9469_05026 1.85e-17 80.1 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia,221N8@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_131371_1 357244.OTBS_1771 6.97e-15 72.0 arCOG06669@1|root,2ZC1E@2|Bacteria,1RBUZ@1224|Proteobacteria,2UIVS@28211|Alphaproteobacteria,47FQY@766|Rickettsiales 766|Rickettsiales - - - - - - - - - - - - - - - k59_9185_2 1417296.U879_13410 7.96e-115 365.0 COG3378@1|root,COG3598@1|root,COG3378@2|Bacteria,COG3598@2|Bacteria,1MV7I@1224|Proteobacteria,2TRS2@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Phage plasmid primase P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N k59_155787_1 997346.HMPREF9374_3443 0.000158 50.4 COG0639@1|root,COG4639@1|root,COG0639@2|Bacteria,COG4639@2|Bacteria,1W6XG@1239|Firmicutes,4I9JG@91061|Bacilli,27D7J@186824|Thermoactinomycetaceae 91061|Bacilli T AAA domain - - - - - - - - - - - - AAA_33,Metallophos k59_34269_1 1609634.A0A0C5AFV4_9VIRU 1.38e-81 261.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_70560_2 553217.ENHAE0001_2557 1.45e-11 69.7 COG1961@1|root,COG1961@2|Bacteria,1R3XB@1224|Proteobacteria,1RSC2@1236|Gammaproteobacteria,3NKN4@468|Moraxellaceae 1236|Gammaproteobacteria L Resolvase, N terminal domain - - - - - - - - - - - - HTH_11,HTH_7,Resolvase k59_301948_3 582744.Msip34_1667 2.45e-10 59.3 COG4333@1|root,COG4333@2|Bacteria,1N19M@1224|Proteobacteria,2VVXJ@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF1643) - - - - - - - - - - - - DUF1643 k59_34276_1 1125973.JNLC01000012_gene891 1.03e-14 79.0 2C1TB@1|root,2ZB27@2|Bacteria,1N020@1224|Proteobacteria,2UP9F@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_180321_2 857293.CAAU_0783 3.37e-29 114.0 2DPDW@1|root,331PC@2|Bacteria,1VX8E@1239|Firmicutes 1239|Firmicutes S Domain of unknown function (DUF4373) - - - - - - - - - - - - DUF4373 k59_70567_1 1609634.A0A0C5AFT2_9VIRU 1.3e-94 289.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_59780_1 652103.Rpdx1_2950 7.19e-77 247.0 COG4373@1|root,COG4373@2|Bacteria,1Q1RY@1224|Proteobacteria,2V9ED@28211|Alphaproteobacteria,3K5IV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Mu-like prophage FluMu protein gp28 - - - - - - - - - - - - - k59_327585_2 1449337.JQLL01000001_gene1489 1.2e-06 50.8 COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes 1239|Firmicutes K Transcriptional - - - - - - - - - - - - HTH_3 k59_84404_3 1301098.PKB_5041 4.75e-39 139.0 COG3935@1|root,COG3935@2|Bacteria,1N2SH@1224|Proteobacteria,1SBMX@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DnaD domain protein - - - - - - - - - - - - - k59_10671_1 1088868.CIN_21470 9.95e-19 88.2 COG0270@1|root,COG0270@2|Bacteria,1NPQG@1224|Proteobacteria,2U226@28211|Alphaproteobacteria 28211|Alphaproteobacteria L C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_181768_1 1504822.CCNO01000015_gene597 9.24e-15 76.6 COG5377@1|root,COG5377@2|Bacteria 2|Bacteria L YqaJ viral recombinase family yqaJ - - - - - - - - - - - YqaJ k59_303445_2 1618247.A0A0C5IMK7_9CIRC 8.79e-08 56.2 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_314988_3 497964.CfE428DRAFT_6469 9.26e-66 226.0 COG0305@1|root,COG0305@2|Bacteria,46SKM@74201|Verrucomicrobia 74201|Verrucomicrobia L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_278285_2 56780.SYN_01547 1.11e-07 58.2 COG4932@1|root,COG4932@2|Bacteria 2|Bacteria M domain protein - - - - - - - - - - - - Cna_B,DUF4998,DUF5013,F5_F8_type_C,Gram_pos_anchor,LRR_5,MucBP k59_327600_1 1288494.EBAPG3_28360 1.03e-06 56.2 COG1216@1|root,COG1216@2|Bacteria,1QP7Y@1224|Proteobacteria,2VMI5@28216|Betaproteobacteria,372J3@32003|Nitrosomonadales 28216|Betaproteobacteria M PFAM Glycosyl transferase, family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_2,Methyltransf_23 k59_362738_1 1123288.SOV_1c10720 9.37e-20 95.1 28I8X@1|root,2Z8BQ@2|Bacteria,1TPNC@1239|Firmicutes,4H385@909932|Negativicutes 909932|Negativicutes - - - - - - - - - - - - - - - k59_339699_3 1219035.NT2_06_02780 2.59e-06 50.4 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,2TSMA@28211|Alphaproteobacteria,2K1FG@204457|Sphingomonadales 204457|Sphingomonadales H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribB - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2,SLT k59_362967_2 1094556.MCY_00355 3.49e-08 59.7 COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2TS8U@28211|Alphaproteobacteria,48T2N@772|Bartonellaceae 28211|Alphaproteobacteria I Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD - 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hexapep,Hexapep_2,LpxD k59_362967_4 1463820.JOGW01000007_gene2073 5.41e-41 152.0 COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria 201174|Actinobacteria E Belongs to the DegT DnrJ EryC1 family degT - - - - - - - - - - - DegT_DnrJ_EryC1 k59_254280_1 483216.BACEGG_02723 3.93e-06 51.6 2BP9Z@1|root,32I1T@2|Bacteria,4PE07@976|Bacteroidetes,2FW3U@200643|Bacteroidia,4AUA1@815|Bacteroidaceae 976|Bacteroidetes - - - - - - - - - - - - - - - k59_375545_3 1234888.K0A2J2_9VIRU 1.09e-39 146.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_181892_1 1175654.A0A0S0NAE3_9CAUD 1.04e-40 158.0 4QB5I@10239|Viruses,4QWYV@35237|dsDNA viruses no RNA stage,4QTTK@28883|Caudovirales,4QM8X@10699|Siphoviridae 10699|Siphoviridae S ATP-dependent DNA helicase activity - - - - - - - - - - - - - k59_84646_1 113355.CM001775_gene2574 1.63e-09 62.8 COG0863@1|root,COG0863@2|Bacteria,1G4CX@1117|Cyanobacteria 1117|Cyanobacteria L DNA methylase - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_84646_2 1410676.JNKL01000006_gene262 4.95e-44 157.0 COG0338@1|root,COG0338@2|Bacteria,1P85S@1224|Proteobacteria,1RMNW@1236|Gammaproteobacteria,1Y3DM@135624|Aeromonadales 135624|Aeromonadales L D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_267173_1 1234888.K0A2J2_9VIRU 1.6e-33 130.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_191334_1 1235794.C811_00606 1.53e-10 61.6 COG1327@1|root,COG1327@2|Bacteria,2IHU9@201174|Actinobacteria,4CVYF@84998|Coriobacteriia 84998|Coriobacteriia K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone k59_388351_5 1234888.K0A2J2_9VIRU 3.73e-124 379.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_191349_3 1385658.U5KNR1_9VIRU 6.84e-24 101.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_388352_1 1707330.A0A0S2C3Q2_9VIRU 9.63e-19 86.7 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_388352_2 1592108.A0A0B4UGN8_9VIRU 1.87e-46 165.0 4QHM9@10239|Viruses 10239|Viruses - - - - - - - - - - - - - - - k59_388352_3 1795988.A0A140CTK3_9VIRU 1.93e-21 92.8 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_191371_1 691965.D4P7L3_9CAUD 1.39e-57 196.0 4QBH7@10239|Viruses,4QWWF@35237|dsDNA viruses no RNA stage,4QQ8R@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_388590_1 46681.XP_001738227.1 1.28e-05 54.3 2CSEE@1|root,2RBK2@2759|Eukaryota,3X9MH@554915|Amoebozoa 554915|Amoebozoa G RNA helicase - - - - - - - - - - - - RNA_helicase k59_192753_2 1234888.K0A2J2_9VIRU 2.32e-46 165.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_192765_1 1692257.A0A0K1RL39_9CIRC 5.31e-66 208.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_304601_1 1120705.FG95_02362 2.64e-06 50.1 COG3773@1|root,COG3773@2|Bacteria,1MWX3@1224|Proteobacteria,2TT15@28211|Alphaproteobacteria,2K40Z@204457|Sphingomonadales 204457|Sphingomonadales M Cell Wall Hydrolase - - - - - - - - - - - - Hydrolase_2 k59_170818_1 272942.RCAP_rcc01080 1.35e-27 112.0 2CZBU@1|root,32T60@2|Bacteria,1N7TC@1224|Proteobacteria,2UIQ6@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_365183_5 279303.Q6J7X1_9CAUD 5.45e-137 411.0 4QCM9@10239|Viruses,4QVZV@35237|dsDNA viruses no RNA stage,4QTYN@28883|Caudovirales,4QMZ7@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_146736_1 1385658.U5KNR1_9VIRU 4.16e-28 114.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_25117_1 445692.E3SP51_9CAUD 1.11e-05 49.3 4QBMX@10239|Viruses,4QV9I@35237|dsDNA viruses no RNA stage,4QQGF@28883|Caudovirales,4QNC1@10744|Podoviridae 10744|Podoviridae S Pfam:Tube - GO:0005575,GO:0019012 - - - - - - - - - - - k59_25117_2 438753.AZC_3583 2.14e-18 94.4 28IA2@1|root,2Z8CQ@2|Bacteria,1PQM2@1224|Proteobacteria,2TUAP@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_134382_2 1618249.A0A0C5IBT4_9CIRC 3.18e-19 93.2 4QB6C@10239|Viruses,4QUKM@29258|ssDNA viruses 10239|Viruses J Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_170897_2 1618260.A0A0C5I2C5_9CIRC 1.99e-21 96.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_207542_4 1028800.RG540_CH08880 8.09e-06 47.8 2EJ3I@1|root,33CUS@2|Bacteria,1NGHC@1224|Proteobacteria,2UJVB@28211|Alphaproteobacteria,4BH02@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_353389_1 1385658.U5KPZ6_9VIRU 1.07e-34 134.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_353389_4 1385658.U5KNR1_9VIRU 3.38e-56 192.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_328982_2 749413.E5DV94_9VIRU 5.48e-09 55.1 4QAZF@10239|Viruses,4QUTY@35237|dsDNA viruses no RNA stage 10239|Viruses S Protein of unknwon function (DUF3310) - - - - - - - - - - - - - k59_328982_3 1160721.RBI_I01166 4.39e-07 55.5 COG1896@1|root,COG1896@2|Bacteria,1TSDU@1239|Firmicutes,24FT8@186801|Clostridia,3WGMJ@541000|Ruminococcaceae 186801|Clostridia S PFAM metal-dependent phosphohydrolase HD sub domain yfbR - 3.1.3.89 ko:K07023,ko:K08722 ko00240,ko01100,map00240,map01100 - R01569,R01664,R01968,R02088,R02102,R10776 RC00017 ko00000,ko00001,ko01000 - - - HD_2,HD_3 k59_328982_4 1980924.B2ZYD3_9CAUD 7.89e-68 224.0 4QBA2@10239|Viruses,4QPPI@28883|Caudovirales,4QIA3@10662|Myoviridae 10662|Myoviridae S Thymidylate synthase - - - - - - - - - - - - - k59_328982_5 5341.XP_007333176.1 8.9e-08 60.8 28HY4@1|root,2S2AC@2759|Eukaryota,3A4KP@33154|Opisthokonta,3P4W1@4751|Fungi,3V1CI@5204|Basidiomycota,22917@155619|Agaricomycetes,3W52T@5338|Agaricales 4751|Fungi B Chromo (CHRromatin Organisation MOdifier) domain - - - - - - - - - - - - Chromo k59_25127_3 1476583.DEIPH_ctg017orf0231 0.00019 45.8 COG0507@1|root,COG0507@2|Bacteria 2|Bacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - - - - - - - - - - AAA_30,HTH_31,N_BRCA1_IG k59_85857_1 1122225.AULQ01000009_gene341 1.98e-38 146.0 2EAST@1|root,334US@2|Bacteria,4NRGD@976|Bacteroidetes,1I583@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - k59_25129_1 313596.RB2501_01430 5.75e-73 226.0 COG2887@1|root,COG2887@2|Bacteria,4P6Q6@976|Bacteroidetes 976|Bacteroidetes L Belongs to the helicase family. UvrD subfamily - - - - - - - - - - - - - k59_280586_1 873513.HMPREF6485_0886 5.87e-06 47.4 COG1694@1|root,COG1694@2|Bacteria 2|Bacteria FG Mazg nucleotide pyrophosphohydrolase MA20_27270 - - - - - - - - - - - MazG k59_317499_1 1150469.RSPPHO_00337 1.65e-45 164.0 COG4227@1|root,COG4227@2|Bacteria,1MU8I@1224|Proteobacteria,2TRIT@28211|Alphaproteobacteria,2JRBB@204441|Rhodospirillales 204441|Rhodospirillales L COG4227 Antirestriction protein - - - - - - - - - - - - DUF1738 k59_317499_3 1331060.RLDS_25925 3.18e-07 50.8 COG1961@1|root,COG1961@2|Bacteria,1R3XB@1224|Proteobacteria,2U5C4@28211|Alphaproteobacteria,2K4CC@204457|Sphingomonadales 204457|Sphingomonadales L DNA invertase - - - - - - - - - - - - HTH_7,Resolvase k59_353987_1 679197.HMPREF9336_02235 2.51e-44 150.0 2DN54@1|root,32VJI@2|Bacteria,2I8AX@201174|Actinobacteria 201174|Actinobacteria L Recombination endonuclease VII - - - - - - - - - - - - Endonuclease_7 k59_353987_5 1589274.A0A0B5A489_9CAUD 1.03e-110 326.0 4QAWG@10239|Viruses,4QPII@28883|Caudovirales,4QKWY@10699|Siphoviridae 10699|Siphoviridae S DNA helicase activity - - - - - - - - - - - - - k59_159480_2 1446473.JHWH01000027_gene1784 5.08e-15 77.8 COG3108@1|root,COG3108@2|Bacteria,1QDAN@1224|Proteobacteria,2TV1K@28211|Alphaproteobacteria,2PWHJ@265|Paracoccus 28211|Alphaproteobacteria S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 k59_98615_1 186617.M9M8L2_9VIRU 7.82e-49 171.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_123042_2 1692257.A0A0K1RL39_9CIRC 2.01e-96 293.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_256574_1 1379717.S5SY19_9CIRC 1.41e-33 132.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_37866_5 710111.FraQA3DRAFT_5920 9.12e-13 71.2 COG0741@1|root,COG0741@2|Bacteria,2I54D@201174|Actinobacteria 201174|Actinobacteria M lytic transglycosylase activity - - - - - - - - - - - - Peptidase_M23,SLT k59_244247_1 1609634.A0A0C5AFV4_9VIRU 3.55e-70 233.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_317567_2 1122971.BAME01000006_gene912 2.54e-11 68.2 COG4123@1|root,COG4123@2|Bacteria,4NIA1@976|Bacteroidetes 976|Bacteroidetes S Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - - - - - - - - - - N6_N4_Mtase k59_74515_1 1133849.O3I_003005 7.49e-26 114.0 COG5002@1|root,COG5002@2|Bacteria,2I2DU@201174|Actinobacteria,4FTXC@85025|Nocardiaceae 201174|Actinobacteria T His Kinase A (phosphoacceptor) domain phoR - 2.7.13.3 ko:K02484 - - - - ko00000,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA k59_318173_1 521719.ATXQ01000001_gene261 2.21e-39 144.0 28HEE@1|root,2Z7QU@2|Bacteria,1MXU6@1224|Proteobacteria,1RZSJ@1236|Gammaproteobacteria,1YF4W@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 k59_172073_1 1380394.JADL01000006_gene5263 2.39e-49 182.0 COG2268@1|root,COG2268@2|Bacteria,1NT13@1224|Proteobacteria,2U335@28211|Alphaproteobacteria,2JXVD@204441|Rhodospirillales 204441|Rhodospirillales S Band 7 protein - - - - - - - - - - - - - k59_26231_1 1618247.A0A0C5IMK7_9CIRC 4.92e-10 64.7 4QEEA@10239|Viruses,4QUMF@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_38353_3 1234888.K0A2R8_9VIRU 3.72e-26 109.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_38353_7 2003327.CAPSD_BPCHP 6.6e-19 92.8 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_50692_5 89187.ISM_07470 4.19e-18 86.3 COG0457@1|root,COG0457@2|Bacteria,1RF9I@1224|Proteobacteria,2U8A6@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Tetratricopeptide repeat - - - - - - - - - - - - - k59_330339_1 1414738.V5UQL8_9CAUD 1.97e-71 240.0 4QGA5@10239|Viruses,4QURD@35237|dsDNA viruses no RNA stage,4QT9N@28883|Caudovirales,4QP47@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_38361_2 1026955.F5B441_9CAUD 5.24e-32 118.0 4QAJX@10239|Viruses,4QUZ8@35237|dsDNA viruses no RNA stage,4QPK4@28883|Caudovirales,4QHZF@10662|Myoviridae 10662|Myoviridae S Pfam:DUF5051 - - - - - - - - - - - - - k59_111935_1 1120977.JHUX01000003_gene1256 2.89e-42 160.0 COG0507@1|root,COG0507@2|Bacteria,1QCFP@1224|Proteobacteria,1S1GX@1236|Gammaproteobacteria,3NIRC@468|Moraxellaceae 1236|Gammaproteobacteria L Helix-turn-helix domain pif1 - - - - - - - - - - - HTH_40,PIF1 k59_51283_1 655097.C8ZKI5_9CAUD 2.94e-61 200.0 4QGM6@10239|Viruses,4QYNV@35237|dsDNA viruses no RNA stage,4QRH4@28883|Caudovirales,4QP0P@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_51283_2 655097.C8ZKI4_9CAUD 2.58e-150 440.0 4QEFX@10239|Viruses,4QYYG@35237|dsDNA viruses no RNA stage,4QRRV@28883|Caudovirales,4QNTK@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_294327_2 1298867.AUES01000007_gene4998 7.1e-47 169.0 COG3378@1|root,COG3378@2|Bacteria,1MV7I@1224|Proteobacteria,2TRS2@28211|Alphaproteobacteria,3JUY6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O D5 N terminal like - - - ko:K06919 - - - - ko00000 - - - D5_N,Prim-Pol k59_172814_1 397945.Aave_1768 5.87e-72 239.0 COG4626@1|root,COG4626@2|Bacteria,1MW7K@1224|Proteobacteria,2VNHP@28216|Betaproteobacteria,4AC68@80864|Comamonadaceae 28216|Betaproteobacteria S Terminase - - - - - - - - - - - - Terminase_1 k59_342774_3 1732201.A0A0N9N7I3_9CIRC 3.72e-19 94.7 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_27046_1 156889.Mmc1_1722 1.32e-18 90.1 COG4675@1|root,COG4675@2|Bacteria,1Q34D@1224|Proteobacteria,2UJKF@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Membrane - - - - - - - - - - - - - k59_160782_1 1618248.A0A0C5IB82_9CIRC 8.01e-22 93.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_75563_2 1609634.A0A0C5ANA6_9VIRU 5.75e-09 56.6 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_2786_1 365528.KB891219_gene818 2.16e-49 168.0 2DC0I@1|root,2ZC7X@2|Bacteria,2IG5R@201174|Actinobacteria 201174|Actinobacteria S P22 coat protein - gene protein 5 - - - - - - - - - - - - P22_CoatProtein k59_2786_2 365528.KB891219_gene817 2.04e-18 85.1 2EH1V@1|root,33ATU@2|Bacteria,2GU12@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_246030_2 1692244.A0A0K1RLR5_9CIRC 2.98e-98 296.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_173409_1 1347342.BN863_28570 7.23e-19 95.1 COG5280@1|root,COG5280@2|Bacteria,4NKDN@976|Bacteroidetes,1I134@117743|Flavobacteriia 976|Bacteroidetes D Phage tail tape measure protein, TP901 family - - - - - - - - - - - - PhageMin_Tail k59_112486_1 298386.PBPRB1277 1.47e-10 66.2 COG5281@1|root,COG5281@2|Bacteria,1QUCD@1224|Proteobacteria,1T1T2@1236|Gammaproteobacteria 1236|Gammaproteobacteria D tape measure protein - - - - - - - - - - - - Phage_HK97_TLTM,TMP_2,Tape_meas_lam_C k59_76057_2 1609634.A0A0C5ANA6_9VIRU 4.18e-08 59.7 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_173410_1 323259.Mhun_0724 5.25e-28 110.0 arCOG07591@1|root,arCOG07591@2157|Archaea,2XX06@28890|Euryarchaeota 28890|Euryarchaeota S von Willebrand factor (vWF) type A domain - - - - - - - - - - - - VWA,VWA_2 k59_100459_1 268748.Q58N40_BPPRP 3.08e-12 67.8 4QAM2@10239|Viruses,4QV3W@35237|dsDNA viruses no RNA stage,4QPGK@28883|Caudovirales,4QNW0@10744|Podoviridae 10744|Podoviridae S exonuclease activity - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - - - - - - - - - - - k59_307286_1 580332.Slit_1922 8.05e-81 265.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,2VM59@28216|Betaproteobacteria 28216|Betaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C k59_307286_3 1122201.AUAZ01000017_gene2962 7.77e-15 87.0 COG4675@1|root,COG4675@2|Bacteria 2|Bacteria M tail collar domain protein - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - Collar,Phage_fiber_2 k59_125120_1 1500301.JQMF01000006_gene1755 3.27e-46 165.0 28MSK@1|root,2ZB0X@2|Bacteria,1R7CY@1224|Proteobacteria,2U2MY@28211|Alphaproteobacteria,4BJ92@82115|Rhizobiaceae 28211|Alphaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_112545_1 546805.B5LJN3_9CAUD 2.03e-34 131.0 4QEGS@10239|Viruses,4QVI7@35237|dsDNA viruses no RNA stage,4QS2V@28883|Caudovirales,4QHWF@10662|Myoviridae 10662|Myoviridae S nicotinate-nucleotide diphosphorylase (carboxylating) activity - - - - - - - - - - - - - k59_379927_1 999141.GME_13570 1.09e-52 172.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,1XJHS@135619|Oceanospirillales 135619|Oceanospirillales L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_64311_1 1109711.G9FHX7_9CAUD 2.37e-42 160.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - k59_295524_1 1379717.S5SY19_9CIRC 2.41e-15 82.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_320064_3 483216.BACEGG_02721 9.73e-07 53.5 2F135@1|root,33U4N@2|Bacteria,4P2MK@976|Bacteroidetes,2FTM1@200643|Bacteroidia,4AT68@815|Bacteroidaceae 976|Bacteroidetes S Capsid protein (F protein) - - - - - - - - - - - - Phage_F k59_222983_1 1618238.A0A0C5IB41_9CIRC 1.02e-08 58.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_52508_2 1475143.W8SNN0_9CIRC 2.26e-34 134.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_198213_5 1111131.HMPREF1255_1449 2.58e-51 187.0 COG0553@1|root,COG0553@2|Bacteria,2IC31@201174|Actinobacteria,4DUM1@85009|Propionibacteriales 201174|Actinobacteria KL SNF2 family N-terminal domain - - - - - - - - - - - - SNF2_N k59_284542_2 2003327.CAPSD_BPCHP 1.31e-60 205.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_28237_2 1692242.A0A0K1RL37_9CIRC 9.22e-79 248.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_125723_2 15368.BRADI1G47210.1 4.32e-43 152.0 2CM75@1|root,2QPHU@2759|Eukaryota,37NYC@33090|Viridiplantae,3G7BP@35493|Streptophyta,3KQBV@4447|Liliopsida,3I32Z@38820|Poales 35493|Streptophyta - - - - - - - - - - - - - - - k59_113092_2 1609634.A0A0C5AFV4_9VIRU 9.72e-86 271.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_28249_1 145579.CAPSD_BPPHM 7.68e-69 224.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_4158_6 2003327.CAPSD_BPCHP 3.3e-52 194.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_332898_1 1040987.AZUY01000006_gene1806 1.25e-06 57.4 COG3598@1|root,COG3598@2|Bacteria,1R4GJ@1224|Proteobacteria,2TUNT@28211|Alphaproteobacteria 28211|Alphaproteobacteria L AAA domain - - - - - - - - - - - - AAA_25 k59_89849_2 1537917.JU82_00895 7.41e-28 110.0 COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,42KZY@68525|delta/epsilon subdivisions,2YMQF@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose gmd - 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd k59_344785_2 557598.LHK_01554 3.26e-53 208.0 COG0503@1|root,COG0503@2|Bacteria 2|Bacteria F purine ribonucleoside salvage apt - 2.4.2.22,2.4.2.7 ko:K00759,ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R00190,R01229,R02142,R04378 RC00063,RC00122 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran k59_101913_1 1234888.K0A2J2_9VIRU 2.32e-117 355.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_101913_2 1234888.K0A2R8_9VIRU 1.85e-41 150.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_101913_6 1234888.K0A2J2_9VIRU 7.47e-60 199.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_15839_1 145579.CAPSD_BPPHM 3.64e-45 164.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_126398_1 936136.ARRT01000006_gene5340 9.45e-41 155.0 COG1783@1|root,COG1783@2|Bacteria,1RAGC@1224|Proteobacteria,2U6JF@28211|Alphaproteobacteria,4BID4@82115|Rhizobiaceae 28211|Alphaproteobacteria S phage Terminase large subunit - - - - - - - - - - - - - k59_162681_1 444875.E3SMF7_9CAUD 0.000249 52.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QNBD@10744|Podoviridae 10744|Podoviridae S outer membrane - - - - - - - - - - - - - k59_174954_6 1380391.JIAS01000015_gene25 5.71e-59 194.0 COG1442@1|root,COG1442@2|Bacteria,1QH4S@1224|Proteobacteria,2U2NZ@28211|Alphaproteobacteria,2JTII@204441|Rhodospirillales 204441|Rhodospirillales M glycosyl transferase family 8 - - - - - - - - - - - - - k59_247455_2 1038860.AXAP01000029_gene755 4.29e-05 47.8 COG5283@1|root,COG5283@2|Bacteria,1PF7V@1224|Proteobacteria,2U3IB@28211|Alphaproteobacteria,3K064@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Phage-related minor tail protein - - - - - - - - - - - - PhageMin_Tail k59_356816_22 394503.Ccel_3152 1.26e-39 157.0 COG0863@1|root,COG0863@2|Bacteria,1TR56@1239|Firmicutes,248NR@186801|Clostridia 186801|Clostridia L Belongs to the N(4) N(6)-methyltransferase family cfr9IM - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_356816_25 551275.KB899544_gene1570 7.46e-46 170.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2TSF9@28211|Alphaproteobacteria,43WCZ@69657|Hyphomonadaceae 28211|Alphaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_356816_26 1392540.P256_00731 8.57e-08 59.7 2EPEW@1|root,33H1I@2|Bacteria,1N6N3@1224|Proteobacteria 1224|Proteobacteria S Bacteriophage replication protein O - - - - - - - - - - - - Phage_rep_O k59_356816_32 512565.AMIS_45990 1.27e-15 73.9 2B4Q9@1|root,31XGJ@2|Bacteria,2IKKF@201174|Actinobacteria,4DFR5@85008|Micromonosporales 201174|Actinobacteria - - - - - - - - - - - - - - - k59_235955_1 948071.S4S2F7_9CAUD 9.64e-07 54.7 4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae 10744|Podoviridae S DNA polymerase family A - GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_78263_2 1788452.A0A190WHG0_9CIRC 1.41e-62 206.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_345718_1 909943.HIMB100_00022990 2.6e-18 87.4 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,2TRCN@28211|Alphaproteobacteria,4BRB3@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - - - - - - - - - - CTP_transf_like,PfkB k59_345718_2 1159870.KB907784_gene2767 1.52e-34 121.0 COG0500@1|root,COG2226@2|Bacteria,1QSZ6@1224|Proteobacteria 1224|Proteobacteria Q methyltransferase - - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - Methyltransf_11,Methyltransf_31 k59_321740_7 742740.HMPREF9474_02263 1.14e-30 113.0 2ARVA@1|root,31H70@2|Bacteria,1V7JT@1239|Firmicutes,24JPE@186801|Clostridia,222RD@1506553|Lachnoclostridium 186801|Clostridia S Bacteriophage HK97-gp10, putative tail-component - - - - - - - - - - - - HK97-gp10_like k59_139117_2 186617.M9M8L2_9VIRU 1.4e-34 130.0 4QFNI@10239|Viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_114514_1 1236542.BALM01000007_gene3443 2.59e-09 58.9 COG2852@1|root,COG2852@2|Bacteria,1N7EJ@1224|Proteobacteria,1SF5D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - DUF559 k59_127200_2 351607.Acel_0457 3.75e-11 62.4 2CC1Y@1|root,32RUK@2|Bacteria,2IQ4Q@201174|Actinobacteria,4ET3Z@85013|Frankiales 201174|Actinobacteria K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA whiB2 - - ko:K18955 - - - - ko00000,ko03000 - - - Whib k59_286560_1 1234888.K0A2R8_9VIRU 8.47e-13 73.6 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_248356_1 12348.Q8SDH3_BPLLH 6.82e-09 62.0 4QAX8@10239|Viruses,4QVB1@35237|dsDNA viruses no RNA stage,4QPHH@28883|Caudovirales,4QKTJ@10699|Siphoviridae 10699|Siphoviridae S calcium ion binding - - - - - - - - - - - - - k59_30109_1 269482.Bcep1808_1173 2.21e-31 128.0 2C5GI@1|root,2Z8C1@2|Bacteria,1R8XM@1224|Proteobacteria,2W1HD@28216|Betaproteobacteria,1KC2X@119060|Burkholderiaceae 28216|Betaproteobacteria S P22 coat protein - gene protein 5 - - - - - - - - - - - - P22_CoatProtein k59_345734_1 44088.Q6VZJ4_CNPV 9.72e-18 86.7 4QB1C@10239|Viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_5723_2 1408418.JNJH01000012_gene3580 3.86e-19 89.0 28N1N@1|root,2ZB7Q@2|Bacteria,1R86T@1224|Proteobacteria,2U0A6@28211|Alphaproteobacteria,2JRMI@204441|Rhodospirillales 204441|Rhodospirillales H Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_1 k59_79091_1 356851.JOAN01000003_gene1451 1.3e-31 124.0 COG4695@1|root,COG4695@2|Bacteria,2GZFX@201174|Actinobacteria 201174|Actinobacteria S Phage portal protein - - - - - - - - - - - - Phage_portal k59_334384_1 1383056.S5YDV9_9CAUD 6.21e-33 134.0 4QW0V@35237|dsDNA viruses no RNA stage,4QR4Y@28883|Caudovirales 28883|Caudovirales - - - GO:0003674,GO:0003824,GO:0004518,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - - - - - - - - - - - k59_186323_1 1379708.S5SYC3_9CIRC 2.01e-22 95.5 4QASI@10239|Viruses,4QUM7@29258|ssDNA viruses 10239|Viruses L Geminivirus coat protein/nuclear export factor BR1 family - GO:0005575,GO:0018995,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0042025,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217 - - - - - - - - - - - k59_6338_1 1476391.X5L0Y9_9CAUD 2.97e-22 102.0 4QB3X@10239|Viruses,4QWKP@35237|dsDNA viruses no RNA stage,4QPEE@28883|Caudovirales,4QNCI@10744|Podoviridae 10744|Podoviridae S VWA-like domain (DUF2201) - - - - - - - - - - - - - k59_346376_2 1229780.BN381_10225 3.75e-05 48.5 COG4122@1|root,COG4122@2|Bacteria,2GQ0Z@201174|Actinobacteria 201174|Actinobacteria S Methyltransferase domain - - - - - - - - - - - - Methyltransf_24 k59_42482_1 5874.XP_954352.1 9.72e-20 93.6 COG0349@1|root,COG0749@1|root,KOG2373@1|root,KOG0950@2759|Eukaryota,KOG2206@2759|Eukaryota,KOG2373@2759|Eukaryota,3YBAR@5794|Apicomplexa,3KA43@422676|Aconoidasida,3Z42K@5863|Piroplasmida 422676|Aconoidasida JL DNA polymerase I - GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7,3.6.4.12 ko:K02335,ko:K17680 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03029,ko03032,ko03400 - - - AAA_25,DNA_pol_A,DNA_pol_A_exo1 k59_370256_2 1401067.HMPREF0872_06805 3.58e-10 60.1 291CT@1|root,2ZNZN@2|Bacteria,1W20H@1239|Firmicutes,4H8SV@909932|Negativicutes 909932|Negativicutes - - - - - - - - - - - - - - - k59_115197_1 69279.BG36_20875 2.15e-13 72.8 COG1783@1|root,COG4373@1|root,COG1783@2|Bacteria,COG4373@2|Bacteria,1PE12@1224|Proteobacteria,2V9EC@28211|Alphaproteobacteria,43QJZ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Mu-like prophage FluMu protein gp28 - - - - - - - - - - - - - k59_236675_2 742740.HMPREF9474_02271 6.8e-157 459.0 28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia,221RR@1506553|Lachnoclostridium 186801|Clostridia S Phage portal protein - - - - - - - - - - - - Phage_portal k59_236675_4 691965.D4P7D6_9CAUD 5.51e-205 601.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - - - - - - - - - - - - - k59_236675_5 428125.CLOLEP_01413 1.04e-33 119.0 2E2Y0@1|root,32XYV@2|Bacteria,1VD9S@1239|Firmicutes,24PK0@186801|Clostridia,3WPDR@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_236675_7 742740.HMPREF9474_02267 3.39e-72 226.0 28NM4@1|root,2ZBMQ@2|Bacteria,1V1QD@1239|Firmicutes,24G1B@186801|Clostridia,221N8@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_236675_8 428125.CLOLEP_01417 8.18e-55 178.0 2CGG9@1|root,2ZVSJ@2|Bacteria,1V633@1239|Firmicutes,24HD0@186801|Clostridia,3WMXK@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - k59_236675_14 428125.CLOLEP_01421 4.82e-38 132.0 2ARVA@1|root,31H70@2|Bacteria,1V7JT@1239|Firmicutes,24JPE@186801|Clostridia,3WP7W@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - HK97-gp10_like k59_236675_15 742733.HMPREF9469_05020 2.33e-136 444.0 COG5412@1|root,COG5412@2|Bacteria,1UVV6@1239|Firmicutes,24F0S@186801|Clostridia,221IX@1506553|Lachnoclostridium 186801|Clostridia S phage tail tape measure protein - - - - - - - - - - - - - k59_42490_1 1416009.V9VCY6_9CAUD 2.89e-54 183.0 4QGGR@10239|Viruses,4QZHR@35237|dsDNA viruses no RNA stage,4QUGZ@28883|Caudovirales,4QNY3@10744|Podoviridae 10744|Podoviridae S viral capsid - - - - - - - - - - - - - k59_200576_1 1121334.KB911068_gene2289 2.09e-34 135.0 COG4695@1|root,COG4695@2|Bacteria,1TP8B@1239|Firmicutes,2497C@186801|Clostridia,3WHWY@541000|Ruminococcaceae 186801|Clostridia S Phage portal protein, HK97 family - - - - - - - - - - - - Phage_portal k59_79105_1 1234888.K0A2J2_9VIRU 8.57e-15 75.5 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_358339_2 931627.MycrhDRAFT_6894 8.62e-22 95.5 2C9AC@1|root,2Z7TR@2|Bacteria,2I07F@201174|Actinobacteria,238FQ@1762|Mycobacteriaceae 201174|Actinobacteria S Phage portal protein, SPP1 Gp6-like - - - - - - - - - - - - Phage_prot_Gp6 k59_177266_1 1235792.C808_00622 7.3e-20 91.7 2C6KN@1|root,32Y69@2|Bacteria,1VANX@1239|Firmicutes,24MNG@186801|Clostridia,27RN3@186928|unclassified Lachnospiraceae 186801|Clostridia S VRR_NUC - - - - - - - - - - - - VRR_NUC k59_67821_1 1379712.S5TMV9_9CIRC 8.8e-17 85.5 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_17821_2 1379720.S5TNF0_9CIRC 5.37e-16 77.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_370933_1 1297863.APJF01000020_gene2704 9.49e-05 53.9 28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TURR@28211|Alphaproteobacteria,3JUCC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 k59_370933_3 1205680.CAKO01000006_gene3232 1.03e-11 70.5 2DTAA@1|root,33JEH@2|Bacteria,1NFFI@1224|Proteobacteria,2UFJK@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_214153_1 1172188.KB911820_gene2842 9.49e-103 314.0 28MN1@1|root,2ZAXN@2|Bacteria,2H2TF@201174|Actinobacteria 201174|Actinobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6C k59_214153_2 1120936.KB907208_gene1068 5.5e-48 157.0 2F5XY@1|root,33YGK@2|Bacteria,2H6A2@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_214153_9 1172188.KB911820_gene2847 3e-205 591.0 COG3567@1|root,COG3567@2|Bacteria,2H48H@201174|Actinobacteria 201174|Actinobacteria S Phage portal protein, SPP1 Gp6-like - - - - - - - - - - - - Phage_prot_Gp6 k59_67827_2 1541887.M9NSX5_9CAUD 1.7e-12 67.4 4QCBZ@10239|Viruses,4QSQC@28883|Caudovirales,4QMXV@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_335144_1 76869.PputGB1_1755 9.69e-09 62.4 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,1RR0M@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_201218_2 1481187.A0A075DXC4_9CAUD 5.56e-51 169.0 4QAVB@10239|Viruses,4QV3G@35237|dsDNA viruses no RNA stage,4QQH3@28883|Caudovirales 28883|Caudovirales S chitinase activity - GO:0000270,GO:0001906,GO:0001907,GO:0005975,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009253,GO:0009605,GO:0009607,GO:0009617,GO:0016032,GO:0016052,GO:0019048,GO:0019058,GO:0019076,GO:0030203,GO:0031640,GO:0035821,GO:0035890,GO:0035891,GO:0039633,GO:0040011,GO:0043170,GO:0043207,GO:0044003,GO:0044004,GO:0044033,GO:0044035,GO:0044040,GO:0044041,GO:0044238,GO:0044278,GO:0044364,GO:0044403,GO:0044419,GO:0044659,GO:0044661,GO:0050896,GO:0051672,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051818,GO:0051883,GO:0052126,GO:0052192,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - - - - - - - - - - - k59_164907_1 1556290.A0A0A0RM00_9CAUD 2.06e-18 90.9 4QAXQ@10239|Viruses,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_214189_1 1676184.A0A186YBN5_9CIRC 8.17e-07 50.4 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_92549_1 398513.BBNG_00849 1.73e-24 108.0 COG4653@1|root,COG4653@2|Bacteria,2I9E6@201174|Actinobacteria,4D045@85004|Bifidobacteriales 201174|Actinobacteria S Phage capsid family - - - - - - - - - - - - Phage_capsid k59_324040_1 1385658.U5KNR1_9VIRU 2.9e-73 234.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_165615_1 688245.CtCNB1_3567 1.33e-17 87.4 COG0740@1|root,COG0740@2|Bacteria,1MUQ9@1224|Proteobacteria,2VPIR@28216|Betaproteobacteria,4AEKF@80864|Comamonadaceae 28216|Betaproteobacteria OU Belongs to the peptidase S14 family - - - - - - - - - - - - CLP_protease k59_311572_1 316055.RPE_1516 2.86e-19 87.8 COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2TT5T@28211|Alphaproteobacteria,3JRQ2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB - 4.2.1.46,4.2.1.76,5.1.3.2 ko:K01710,ko:K01784,ko:K12450 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 M00361,M00362,M00632,M00793 R00291,R00293,R02984,R06513 RC00289,RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd k59_311572_2 187303.BN69_2082 1.21e-25 104.0 COG0673@1|root,COG0673@2|Bacteria 2|Bacteria S inositol 2-dehydrogenase activity - - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C k59_262384_2 745310.G432_05115 1e-13 68.9 2DS78@1|root,33EV6@2|Bacteria,1PA7T@1224|Proteobacteria,2UWNK@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_43981_1 596152.DesU5LDRAFT_3296 7.01e-09 61.2 COG0305@1|root,COG0305@2|Bacteria,1PZ6S@1224|Proteobacteria,42YZ3@68525|delta/epsilon subdivisions,2WU0W@28221|Deltaproteobacteria,2MAW9@213115|Desulfovibrionales 28221|Deltaproteobacteria L Toprim-like - - - - - - - - - - - - DnaB_C,Toprim_2 k59_348056_1 1385658.U5KPZ6_9VIRU 2.29e-17 86.3 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_165619_1 331678.Cphamn1_0365 2.52e-18 87.8 COG1573@1|root,COG1573@2|Bacteria,1FDUS@1090|Chlorobi 1090|Chlorobi L TIGRFAM phage SPO1 DNA polymerase-related protein - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_359625_2 1282360.ABAC460_19840 4.81e-75 241.0 COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria 1224|Proteobacteria C SMART Elongator protein 3 MiaB NifB - - - - - - - - - - - - B12-binding,Radical_SAM k59_141359_1 29306.JOBE01000027_gene2209 3.88e-20 93.6 29M5Z@1|root,3083E@2|Bacteria,2IKVT@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_104806_1 158500.BV97_05670 1.09e-104 317.0 COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,2TUCJ@28211|Alphaproteobacteria,2KDAD@204457|Sphingomonadales 204457|Sphingomonadales H C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_80679_1 1031288.AXAA01000004_gene1847 1.51e-07 52.8 COG3339@1|root,COG3339@2|Bacteria,1VAM6@1239|Firmicutes,24KQN@186801|Clostridia,36KET@31979|Clostridiaceae 186801|Clostridia S Protein of unknown function (DUF1232) - - - - - - - - - - - - DUF1232 k59_116683_1 1210884.HG799467_gene13131 3.11e-95 294.0 COG0553@1|root,COG0553@2|Bacteria 2|Bacteria L helicase activity - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_18619_1 391616.OA238_c16240 1.09e-10 71.2 COG3598@1|root,COG3598@2|Bacteria,1R5TK@1224|Proteobacteria,2TZF9@28211|Alphaproteobacteria 28211|Alphaproteobacteria L AAA domain - - - - - - - - - - - - AAA_25 k59_372626_6 1122243.KB903794_gene1727 4.15e-65 217.0 COG0582@1|root,COG0582@2|Bacteria,1MVZB@1224|Proteobacteria,1RP4Y@1236|Gammaproteobacteria,3NK6F@468|Moraxellaceae 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family - - - ko:K14059 - - - - ko00000 - - - Arm-DNA-bind_2,Phage_integrase k59_337017_1 1537917.JU82_03905 2.93e-32 130.0 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,42QJ2@68525|delta/epsilon subdivisions,2YNBV@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S COGs COG3864 conserved - - - - - - - - - - - - DUF2201,DUF2201_N k59_44900_1 1618248.A0A0C5IB82_9CIRC 5.06e-34 125.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_215969_1 1788452.A0A190WHG0_9CIRC 6.22e-12 69.3 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_130453_2 1415148.V5Q7E3_9CAUD 4.66e-23 99.0 4QGPT@10239|Viruses,4QQI9@28883|Caudovirales,4QMUP@10699|Siphoviridae 10699|Siphoviridae S DNA catabolic process, endonucleolytic - - - - - - - - - - - - - k59_19419_2 366394.Smed_1914 1.15e-43 153.0 COG0270@1|root,COG0270@2|Bacteria,1R6IB@1224|Proteobacteria,2TU8N@28211|Alphaproteobacteria,4BDZA@82115|Rhizobiaceae 28211|Alphaproteobacteria L DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - - k59_349078_1 1392486.JIAF01000004_gene2041 6.64e-32 135.0 COG1196@1|root,COG1196@2|Bacteria,4NMBI@976|Bacteroidetes,2FR6N@200643|Bacteroidia 976|Bacteroidetes D nuclear chromosome segregation - - - - - - - - - - - - - k59_179283_4 1396141.BATP01000035_gene4051 1.18e-33 128.0 COG4122@1|root,COG4122@2|Bacteria 2|Bacteria E O-methyltransferase activity - - - - - - - - - - - - Methyltransf_24 k59_130538_1 1475143.W8SNN0_9CIRC 7.19e-47 167.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_8539_4 913970.F8RW84_9VIRU 4.08e-23 104.0 4QCVK@10239|Viruses,4QUMV@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_45900_1 1174529.WSI_05020 1e-12 76.6 290X3@1|root,2ZNIW@2|Bacteria,1P7TA@1224|Proteobacteria,2UXFQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_203886_1 882.DVU_1724 1.93e-45 164.0 COG5362@1|root,COG5362@2|Bacteria,1PYY9@1224|Proteobacteria,435M3@68525|delta/epsilon subdivisions,2WZZT@28221|Deltaproteobacteria,2M981@213115|Desulfovibrionales 28221|Deltaproteobacteria S TIGRFAM Phage - - - - - - - - - - - - - k59_155636_1 1556290.A0A0A0RM00_9CAUD 6.33e-79 255.0 4QAXQ@10239|Viruses,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_95403_1 1340745.R9TE46_9VIRU 2.34e-95 300.0 4QHQH@10239|Viruses 10239|Viruses S Bacteriophage replication gene A protein (GPA) - - - - - - - - - - - - - k59_34110_1 1609634.A0A0C5AFV4_9VIRU 2.32e-37 142.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_290592_2 1122963.AUHB01000028_gene1941 9.17e-103 310.0 28MC2@1|root,2ZAQD@2|Bacteria,1R5I0@1224|Proteobacteria,2TUSQ@28211|Alphaproteobacteria,3710N@31993|Methylocystaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_264170_1 1556290.A0A0A0RM00_9CAUD 4.13e-58 199.0 4QAXQ@10239|Viruses,4QRFY@28883|Caudovirales,4QM52@10699|Siphoviridae 10699|Siphoviridae S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor - - - - - - - - - - - - - k59_118359_13 1502724.FF80_03299 4.52e-128 372.0 COG0175@1|root,COG0175@2|Bacteria 2|Bacteria EH sulfate reduction - - - - - - - - - - - - PAPS_reduct k59_118359_14 1401446.V6F7R7_9CAUD 4.79e-25 107.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QNBP@10744|Podoviridae 10744|Podoviridae S N-methyltransferase activity - - - - - - - - - - - - - k59_118359_15 1408428.JNJP01000061_gene809 2.27e-08 58.5 COG0593@1|root,COG0593@2|Bacteria,1RA1W@1224|Proteobacteria,43BIV@68525|delta/epsilon subdivisions,2X6XA@28221|Deltaproteobacteria,2MH7X@213115|Desulfovibrionales 28221|Deltaproteobacteria L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids - - - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,IstB_IS21 k59_118359_17 1510531.JQJJ01000011_gene2867 2.95e-36 127.0 COG4422@1|root,COG4422@2|Bacteria,1MXQI@1224|Proteobacteria,2TVMB@28211|Alphaproteobacteria,3JSEA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF5131) - - - - - - - - - - - - DUF5131 k59_290691_1 1144342.PMI40_04514 1.01e-19 92.8 COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,2VPZQ@28216|Betaproteobacteria,473VP@75682|Oxalobacteraceae 28216|Betaproteobacteria L uracil-DNA glycosylase dpo - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG k59_203972_2 1121440.AUMA01000005_gene2577 3.24e-19 90.9 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1R7DJ@1224|Proteobacteria,4321W@68525|delta/epsilon subdivisions,2WWR1@28221|Deltaproteobacteria,2M9G9@213115|Desulfovibrionales 28221|Deltaproteobacteria H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - - - - - - - - - - CTP_transf_like,PfkB k59_385544_2 1235792.C808_03072 7.82e-11 62.8 COG0338@1|root,COG0338@2|Bacteria,1UBIY@1239|Firmicutes,24D2Y@186801|Clostridia,27N0A@186928|unclassified Lachnospiraceae 186801|Clostridia L D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 k59_349853_1 1415778.JQMM01000001_gene317 3.89e-96 324.0 COG0823@1|root,COG0823@2|Bacteria,1R4CN@1224|Proteobacteria,1S0NH@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - PD40 k59_338047_1 1122147.AUEH01000027_gene2761 6.96e-23 102.0 COG1061@1|root,COG1061@2|Bacteria,1TQ62@1239|Firmicutes,4HAJ1@91061|Bacilli,3F3YQ@33958|Lactobacillaceae 91061|Bacilli L Helicase C-terminal domain protein - - - - - - - - - - - - Helicase_C,ResIII k59_313392_2 716928.AJQT01000025_gene4005 1.54e-48 164.0 COG3926@1|root,COG3926@2|Bacteria,1MVXW@1224|Proteobacteria,2TT3H@28211|Alphaproteobacteria,4BG95@82115|Rhizobiaceae 28211|Alphaproteobacteria S Glycosyl hydrolase 108 - - - - - - - - - - - - Glyco_hydro_108,PG_binding_1,PG_binding_3 k59_82662_1 1504822.CCNO01000015_gene594 1.08e-08 60.8 COG0553@1|root,COG0863@1|root,COG0553@2|Bacteria,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_46005_3 573.JG24_10890 7.2e-30 109.0 2CH99@1|root,32S5M@2|Bacteria,1N2GH@1224|Proteobacteria,1T0UT@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Recombination enhancement, RecA-dependent nuclease - - - - - - - - - - - - RecA_dep_nuc k59_46005_4 665942.HMPREF1022_00118 9.76e-31 121.0 2C9JF@1|root,32RPD@2|Bacteria,1N8CG@1224|Proteobacteria,42REW@68525|delta/epsilon subdivisions,2WNQ1@28221|Deltaproteobacteria,2MB30@213115|Desulfovibrionales 28221|Deltaproteobacteria S ERF superfamily - - - - - - - - - - - - ERF k59_156623_1 223295.REP_MYMVV 2.21e-12 70.9 4QB6C@10239|Viruses,4QUKM@29258|ssDNA viruses 10239|Viruses J Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_119176_1 1329516.JPST01000008_gene1995 1.08e-09 66.6 COG3023@1|root,COG3023@2|Bacteria,1TR62@1239|Firmicutes,4HGHR@91061|Bacilli,27B79@186824|Thermoactinomycetaceae 91061|Bacilli V Ami_2 - - - - - - - - - - - - Amidase_2,SLT k59_35117_1 1123279.ATUS01000005_gene3102 1.38e-19 94.0 2CJWY@1|root,31CWF@2|Bacteria,1RKEF@1224|Proteobacteria,1S75P@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_361989_1 1609634.A0A0C5AFV4_9VIRU 5.59e-83 265.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_168035_2 589924.Ferp_0513 8.55e-47 171.0 COG0714@1|root,arCOG00436@2157|Archaea,2XWN2@28890|Euryarchaeota,24782@183980|Archaeoglobi 183980|Archaeoglobi S ATPase associated with various cellular activities AAA_5 - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_5 k59_168035_3 1121952.ATXT01000011_gene3059 0.000116 50.8 COG2314@1|root,COG2314@2|Bacteria,2IH46@201174|Actinobacteria,4FNSH@85023|Microbacteriaceae 201174|Actinobacteria S TM2 domain - - - - - - - - - - - - DUF2510,DUF4352 k59_350719_1 1385658.U5KPZ6_9VIRU 3.44e-32 127.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_83509_2 1526550.A0A088F868_9VIRU 1.29e-20 86.3 4QD1J@10239|Viruses 10239|Viruses S Protein of unknown function (DUF1364) - - - - - - - - - - - - - k59_21238_1 1618248.A0A0C5IB82_9CIRC 3.78e-61 201.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_21238_3 1379713.S5SYD9_9CIRC 3.48e-24 98.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_291298_3 1123399.AQVE01000045_gene3190 1.07e-102 322.0 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,1RQFD@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage terminase, large subunit Z012_12305 - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C k59_361992_3 938709.AUSH02000023_gene1941 3.75e-45 159.0 294MN@1|root,2ZS13@2|Bacteria,4P817@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - k59_35124_1 1161931.J7FA60_9CAUD 1.21e-55 198.0 4QB9Y@10239|Viruses,4QWGZ@35237|dsDNA viruses no RNA stage,4QPTT@28883|Caudovirales,4QJD7@10662|Myoviridae 10662|Myoviridae S hydrolase activity - - - - - - - - - - - - - k59_96543_2 7209.EFO25451.1 4.51e-10 63.9 2EWQP@1|root,2SYH6@2759|Eukaryota 2759|Eukaryota S RNA helicase - - - - - - - - - - - - RNA_helicase,Viral_Rep k59_303493_4 1207063.P24_13773 1.97e-05 55.5 COG4733@1|root,COG4733@2|Bacteria,1R7KR@1224|Proteobacteria,2TWI9@28211|Alphaproteobacteria,2JUCZ@204441|Rhodospirillales 204441|Rhodospirillales S Putative phage tail protein - - - - - - - - - - - - Phage-tail_3 k59_120021_1 360910.BAV0432 1.48e-11 69.7 COG3170@1|root,COG3170@2|Bacteria,1Q45C@1224|Proteobacteria,2W196@28216|Betaproteobacteria 28216|Betaproteobacteria NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - k59_375390_1 314265.R2601_22876 1.97e-06 55.8 COG5511@1|root,COG5511@2|Bacteria,1MVN4@1224|Proteobacteria,2TSGI@28211|Alphaproteobacteria 28211|Alphaproteobacteria OU Phage portal protein lambda family - - - - - - - - - - - - Phage_portal_2 k59_145138_1 563192.HMPREF0179_03434 4.14e-39 152.0 28IA2@1|root,2Z8CQ@2|Bacteria,1PQM2@1224|Proteobacteria,42Y9U@68525|delta/epsilon subdivisions,2WTUC@28221|Deltaproteobacteria,2MARZ@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - k59_327665_1 323097.Nham_3328 4.95e-33 133.0 COG5301@1|root,COG5301@2|Bacteria,1N6XX@1224|Proteobacteria,2USJX@28211|Alphaproteobacteria 28211|Alphaproteobacteria G cellulose 1,4-beta-cellobiosidase activity - - - - - - - - - - - - - k59_47706_1 1385658.U5KPZ6_9VIRU 5e-59 201.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_47706_6 1609634.A0A0C5AFT2_9VIRU 4.88e-28 113.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_241785_1 661478.OP10G_0157 3.57e-33 129.0 COG1783@1|root,COG1783@2|Bacteria 2|Bacteria S DNA packaging - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_6 k59_84522_1 1120971.AUCA01000053_gene371 8.5e-14 70.9 COG0863@1|root,COG0863@2|Bacteria,1UZIN@1239|Firmicutes,4HU16@91061|Bacilli 91061|Bacilli L DNA methylase - - - - - - - - - - - - N6_N4_Mtase k59_241823_1 1234888.K0A2J2_9VIRU 5.11e-66 218.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_303511_1 1117108.PAALTS15_09970 1.91e-15 76.6 2EI4V@1|root,33BW7@2|Bacteria,1VKQH@1239|Firmicutes,4HRPN@91061|Bacilli 91061|Bacilli S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 k59_181821_1 105154.Q9MBU6_9VIRU 7.78e-84 267.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_376507_3 1385658.U5KPZ6_9VIRU 1.17e-206 592.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_376507_5 1385658.U5KNR1_9VIRU 4.52e-42 153.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_169975_1 204669.Acid345_2911 2.81e-56 193.0 COG2304@1|root,COG2304@2|Bacteria,3Y6GT@57723|Acidobacteria,2JKSI@204432|Acidobacteriia 204432|Acidobacteriia S TROVE domain - - - - - - - - - - - - TROVE k59_364045_5 459349.CLOAM0215 6.35e-26 102.0 COG3772@1|root,COG3772@2|Bacteria 2|Bacteria S cytolysis by virus of host cell - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_364045_8 1121948.AUAC01000007_gene413 3.79e-16 88.2 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2TS2G@28211|Alphaproteobacteria,43X4X@69657|Hyphomonadaceae 28211|Alphaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k59_364045_12 1121396.KB893112_gene2006 5.52e-44 149.0 COG2110@1|root,COG2110@2|Bacteria,1R2H8@1224|Proteobacteria,42SEQ@68525|delta/epsilon subdivisions,2WPTN@28221|Deltaproteobacteria,2MK9R@213118|Desulfobacterales 28221|Deltaproteobacteria S Macro domain - - - - - - - - - - - - Macro k59_364045_13 1168034.FH5T_14940 1.44e-17 79.3 COG1525@1|root,COG1525@2|Bacteria,4NR4U@976|Bacteroidetes 976|Bacteroidetes L Staphylococcal nuclease homologue - - 3.1.31.1 ko:K01174 - - - - ko00000,ko01000 - - - SNase k59_364045_14 1366055.S5M3Y0_9CAUD 3.96e-32 118.0 4QB2U@10239|Viruses,4QVJC@35237|dsDNA viruses no RNA stage,4QTMH@28883|Caudovirales 28883|Caudovirales S Pfam:GTA_holin_3TM - - - - - - - - - - - - - k59_364045_15 1035191.HMPREF0185_01795 4.39e-17 80.1 2E6PI@1|root,3319W@2|Bacteria,1RCIK@1224|Proteobacteria,2UFSS@28211|Alphaproteobacteria,2KJ8M@204458|Caulobacterales 204458|Caulobacterales - - - - - - - - - - - - - - - k59_376588_2 1449126.JQKL01000003_gene1695 0.000657 47.0 28W6R@1|root,2ZI7D@2|Bacteria,1V1MZ@1239|Firmicutes,24FAN@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - k59_190853_1 1123508.JH636442_gene4470 4.59e-18 93.6 COG3087@1|root,COG3087@2|Bacteria,2IX3F@203682|Planctomycetes 203682|Planctomycetes D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - - - - - - - - - - - k59_170080_1 32057.KB217481_gene8484 2.19e-14 83.2 COG0464@1|root,COG0464@2|Bacteria,1G1UP@1117|Cyanobacteria,1HKFH@1161|Nostocales 1117|Cyanobacteria O AAA domain (Cdc48 subfamily) - - - - - - - - - - - - AAA k59_388287_2 1379715.S5TMW6_9CIRC 7.63e-52 180.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_255093_3 105154.Q9MBU6_9VIRU 1.71e-71 232.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_279343_1 1234888.K0A2J2_9VIRU 1.45e-51 181.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_364052_7 443254.Marpi_0340 4.83e-19 90.9 COG1408@1|root,COG1408@2|Bacteria,2GDNN@200918|Thermotogae 200918|Thermotogae L metallophosphoesterase - - - - - - - - - - - - - k59_255095_1 1692252.A0A0K1RL35_9CIRC 2.77e-54 180.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_255095_3 1692257.A0A0K1RL39_9CIRC 3.38e-43 152.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_388288_7 1795988.A0A140CTK3_9VIRU 8.57e-12 73.2 4QB6C@10239|Viruses 10239|Viruses L Geminivirus Rep catalytic domain - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051701,GO:0051704 - - - - - - - - - - - k59_195138_1 1247726.MIM_c10690 2.15e-32 125.0 COG3756@1|root,COG3756@2|Bacteria,1N7P7@1224|Proteobacteria,2VTUI@28216|Betaproteobacteria,3T864@506|Alcaligenaceae 28216|Betaproteobacteria S Protein of unknown function (DUF1376) - - - - - - - - - - - - DUF1376 k59_146445_2 1122991.BAIZ01000021_gene1635 0.000126 50.4 COG5283@1|root,COG5283@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_280243_3 105154.Q9MBU6_9VIRU 1.84e-12 66.6 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_97765_2 649747.HMPREF0083_01683 1.38e-11 68.9 COG4373@1|root,COG4373@2|Bacteria,1TQNK@1239|Firmicutes,4HDES@91061|Bacilli,26WPR@186822|Paenibacillaceae 91061|Bacilli S Mu-like prophage FluMu protein gp28 gp17a - - - - - - - - - - - Terminase_6,Terminase_6C k59_377343_1 1444712.BN1013_01280 3.01e-235 671.0 COG0209@1|root,COG0209@2|Bacteria,2JFJ7@204428|Chlamydiae 204428|Chlamydiae F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides rtpR - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - - k59_377343_4 260827.Q6R6A4_9CAUD 2.47e-60 216.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales 28883|Caudovirales S N-methyltransferase activity - - - - - - - - - - - - - k59_353092_1 1986029.Q9MBM3_9VIRU 3.35e-28 110.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_12627_1 2340.JV46_20980 1.19e-49 162.0 COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,1S3YC@1236|Gammaproteobacteria,1J5Z7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_H k59_12627_8 595494.Tola_0336 1.46e-05 57.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1Y479@135624|Aeromonadales 135624|Aeromonadales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_292252_1 935866.JAER01000081_gene3681 2.26e-09 63.9 COG5412@1|root,COG5412@2|Bacteria,2IH91@201174|Actinobacteria 201174|Actinobacteria E phage tail tape measure protein - - - - - - - - - - - - - k59_340711_1 1298858.AUEL01000029_gene95 7.44e-55 199.0 COG1345@1|root,COG1345@2|Bacteria,1QZZ9@1224|Proteobacteria,2TZSX@28211|Alphaproteobacteria 28211|Alphaproteobacteria N Prophage tail length tape measure protein - - - - - - - - - - - - TMP_2 k59_340711_3 1408428.JNJP01000077_gene2795 7.11e-21 89.4 2BENR@1|root,328EB@2|Bacteria,1RHI2@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_170579_1 1329516.JPST01000009_gene2081 0.000257 46.6 COG4641@1|root,COG4641@2|Bacteria,1TR7G@1239|Firmicutes 1239|Firmicutes P Spore maturation protein CgeB - - - ko:K06320 - - - - ko00000 - - - DUF3880,Glyco_trans_1_2 k59_170579_2 1415775.U729_3209 3.04e-17 82.8 2DR9Y@1|root,33AUY@2|Bacteria,1VEP1@1239|Firmicutes,24VBK@186801|Clostridia 186801|Clostridia L HNH endonuclease - - - - - - - - - - - - HNH_3,NUMOD4 k59_97808_1 768066.HELO_2629 6.76e-30 129.0 COG0454@1|root,COG0456@2|Bacteria,1RJ9R@1224|Proteobacteria 1224|Proteobacteria K Muramidase (Phage lambda lysozyme) - - - - - - - - - - - - - k59_170609_1 1005995.GTPT_1612 4.99e-37 134.0 COG1403@1|root,COG1403@2|Bacteria,1PSJS@1224|Proteobacteria,1TC4G@1236|Gammaproteobacteria,4BVT4@82986|Tatumella 1236|Gammaproteobacteria V Bacteriophage Lambda NinG protein - - - - - - - - - - - - NinG k59_170609_3 1122201.AUAZ01000021_gene3139 6.28e-19 85.1 2CJKM@1|root,314EI@2|Bacteria,1RGVN@1224|Proteobacteria,1T082@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_170609_4 1408428.JNJP01000003_gene3493 9.33e-64 204.0 COG0270@1|root,COG0270@2|Bacteria 2|Bacteria L DNA (cytosine-5-)-methyltransferase activity - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase k59_170609_5 157783.LK03_14945 4.38e-09 62.8 COG0640@1|root,COG0640@2|Bacteria,1RGKD@1224|Proteobacteria,1S53G@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Helix-turn-helix domain - - - - - - - - - - - - HTH_36 k59_170609_6 693746.OBV_42570 4.98e-82 253.0 COG0175@1|root,COG0175@2|Bacteria,1UZK3@1239|Firmicutes,24CWM@186801|Clostridia,2N8BZ@216572|Oscillospiraceae 186801|Clostridia EH Psort location Cytoplasmic, score - - - - - - - - - - - - - k59_195187_1 1415775.U729_3133 1.86e-16 84.3 COG0791@1|root,COG4193@1|root,COG0791@2|Bacteria,COG4193@2|Bacteria,1TSZR@1239|Firmicutes 1239|Firmicutes G COG4193 Beta- N-acetylglucosaminidase - - - - - - - - - - - - Glucosaminidase k59_328770_1 1692259.A0A0K1RL59_9CIRC 3.55e-22 99.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_158731_1 438753.AZC_3589 1.27e-92 295.0 COG0209@1|root,COG0209@2|Bacteria,1N0E3@1224|Proteobacteria,2UQM4@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Ribonucleotide reductase, barrel domain - - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - Ribonuc_red_lgC k59_122835_3 697282.Mettu_0924 4.58e-09 56.2 COG3926@1|root,COG3926@2|Bacteria,1MVXW@1224|Proteobacteria,1RRB6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S secretion activating protein - - - - - - - - - - - - Glyco_hydro_108,PG_binding_3 k59_183077_1 1391432.V5R3S6_9CAUD 2.68e-57 190.0 4QAIJ@10239|Viruses,4QVZ9@35237|dsDNA viruses no RNA stage,4QPXI@28883|Caudovirales,4QM02@10699|Siphoviridae 10699|Siphoviridae S C-5 cytosine-specific DNA methylase - - - - - - - - - - - - - k59_353771_1 335543.Sfum_1893 1.53e-13 82.4 COG3210@1|root,COG4723@1|root,COG4733@1|root,COG3210@2|Bacteria,COG4723@2|Bacteria,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,42QDD@68525|delta/epsilon subdivisions,2WIU9@28221|Deltaproteobacteria 28221|Deltaproteobacteria U Phage-related protein, tail - - - - - - - - - - - - Phage-tail_3 k59_292884_1 1692258.A0A0K1RL51_9CIRC 6.63e-93 283.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_244054_1 1234888.K0A2J2_9VIRU 1.19e-96 304.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_244054_3 1234888.K0A2R8_9VIRU 3.56e-46 163.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses 10239|Viruses L endonuclease activity - - - - - - - - - - - - - k59_377971_6 1449351.RISW2_03825 5.28e-22 92.0 COG3750@1|root,COG3750@2|Bacteria,1N77J@1224|Proteobacteria,2UFX6@28211|Alphaproteobacteria,4KP04@93682|Roseivivax 28211|Alphaproteobacteria S COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins - - - - - - - - - - - - DUF2312 k59_98437_1 1498011.A0A096XUX6_9CAUD 1.05e-63 223.0 4QCZC@10239|Viruses,4QRH3@28883|Caudovirales 28883|Caudovirales S Bacterial DNA polymerase III alpha subunit - - - - - - - - - - - - - k59_171298_2 1340434.AXVA01000004_gene2641 1.34e-30 126.0 COG1653@1|root,COG3757@1|root,COG4733@1|root,COG1653@2|Bacteria,COG3757@2|Bacteria,COG4733@2|Bacteria 2|Bacteria S cellulase activity lyc GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.17,3.2.1.8 ko:K01181,ko:K01185,ko:K02027,ko:K07273,ko:K07451,ko:K17315,ko:K17318 ko02010,map02010 M00207,M00603,M00605 - - ko00000,ko00001,ko00002,ko01000,ko02000,ko02048 3.A.1.1,3.A.1.1.24,3.A.1.1.29,3.A.1.1.30,3.A.1.1.9 - - Glyco_hydro_25,LysM,Phage-tail_3 k59_365499_1 1327981.S0A1R5_9CAUD 6.07e-25 110.0 4QGUS@10239|Viruses,4QX38@35237|dsDNA viruses no RNA stage,4QRVV@28883|Caudovirales,4QN8J@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_159258_1 856793.MICA_2369 6.69e-08 60.8 COG2911@1|root,COG5295@1|root,COG2911@2|Bacteria,COG5295@2|Bacteria,1NDSM@1224|Proteobacteria,2UK7X@28211|Alphaproteobacteria,4BT5Y@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria UW Chaperone of endosialidase - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - Peptidase_S74 k59_159258_4 716928.AJQT01000109_gene1217 1.48e-47 157.0 2FEUE@1|root,346TC@2|Bacteria,1MZPB@1224|Proteobacteria,2UC4Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_62211_1 1692252.A0A0K1RL35_9CIRC 5.54e-06 53.1 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_317275_1 260827.Q6R6B4_9CAUD 1.49e-84 269.0 4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses no RNA stage,4QQFH@28883|Caudovirales,4QNDH@10744|Podoviridae 10744|Podoviridae S Bacteriophage head to tail connecting protein - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704 - - - - - - - - - - - k59_377974_1 1114964.L485_16320 2.64e-50 173.0 COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1MVH7@1224|Proteobacteria,2TRNA@28211|Alphaproteobacteria,2K05E@204457|Sphingomonadales 204457|Sphingomonadales KL DNA methylase - - - - - - - - - - - - N6_N4_Mtase,ParBc k59_1234_1 102125.Xen7305DRAFT_00008360 3.52e-19 93.2 COG4886@1|root,COG4886@2|Bacteria,1G0NZ@1117|Cyanobacteria,3VKP8@52604|Pleurocapsales 1117|Cyanobacteria S Leucine-rich repeat (LRR) protein - - - ko:K13730 ko05100,map05100 - - - ko00000,ko00001 - - - - k59_268976_2 330214.NIDE2334 5.9e-30 124.0 COG0438@1|root,COG1215@1|root,COG1216@1|root,COG2227@1|root,COG3118@1|root,COG0438@2|Bacteria,COG1215@2|Bacteria,COG1216@2|Bacteria,COG2227@2|Bacteria,COG3118@2|Bacteria 2|Bacteria O belongs to the thioredoxin family celD - - ko:K02453,ko:K07280,ko:K20444,ko:K20543 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko01000,ko01005,ko02000,ko02044 1.B.55.3,3.A.15,4.D.1.3 GT2,GT4 - BCSC_C,Glyco_transf_41,Glycos_transf_2,TPR_16,TPR_19,TPR_8 k59_220772_2 398580.Dshi_0263 2.44e-11 67.0 COG4076@1|root,COG4076@2|Bacteria,1QXIM@1224|Proteobacteria,2TYHF@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 k59_147555_2 1692244.A0A0K1RLR5_9CIRC 1.71e-51 179.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_135295_1 1618259.A0A0C5I2B5_9CIRC 2.88e-69 221.0 4QE84@10239|Viruses,4QUKR@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_305692_1 796940.HMPREF9628_00135 6.6e-17 87.8 COG5283@1|root,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,25E9Q@186801|Clostridia 186801|Clostridia M phage tail tape measure protein - - - - - - - - - - - - PhageMin_Tail k59_86763_1 1692244.A0A0K1RLR5_9CIRC 4.57e-89 272.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_74790_1 945713.IALB_2257 3.38e-44 152.0 COG3298@1|root,COG3298@2|Bacteria 2|Bacteria L Predicted 3'-5' exonuclease related to the exonuclease domain of PolB wlaX - - ko:K07501 - - - - ko00000 - - - DNA_pol_B_exo2 k59_50440_2 192222.Cj1128c 8.22e-08 60.5 COG1215@1|root,COG1215@2|Bacteria,1R5JQ@1224|Proteobacteria,43BVH@68525|delta/epsilon subdivisions,2YMCH@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria M hmm pf00535 pglI GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046527,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.293 ko:K17250 - - - - ko00000,ko01000,ko01003 - GT2 - Glycos_transf_2 k59_293563_3 1556290.A0A0A0RQH0_9CAUD 1.85e-10 73.9 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - k59_256951_2 1609634.A0A0C5AFT2_9VIRU 7.3e-117 348.0 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_256951_4 1609634.A0A0C5AFV4_9VIRU 4.8e-149 444.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - k59_256951_5 1609634.A0A0C5ANA6_9VIRU 3.11e-22 96.7 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_232586_1 1165094.RINTHH_3920 1.66e-21 95.1 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_232586_2 145579.C_BPPHM 4.28e-10 58.2 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_317953_1 1556290.A0A0A0RSX5_9CAUD 1.26e-44 154.0 4QCAU@10239|Viruses,4QPJ6@28883|Caudovirales,4QKZJ@10699|Siphoviridae 10699|Siphoviridae S Pfam:GP88 - - - - - - - - - - - - - k59_111155_1 644107.SL1157_A0033 1.86e-20 92.0 COG1922@1|root,COG2148@1|root,COG1922@2|Bacteria,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,2U7DN@28211|Alphaproteobacteria,4NC2K@97050|Ruegeria 28211|Alphaproteobacteria M hmm pf02397 - - - - - - - - - - - - Bac_transf,CoA_binding_3,Glyco_tran_WecB k59_196202_1 1238450.VIBNISOn1_550017 1.42e-34 123.0 COG2852@1|root,COG2852@2|Bacteria,1N2UX@1224|Proteobacteria,1TIHC@1236|Gammaproteobacteria,1XZ4M@135623|Vibrionales 135623|Vibrionales S Protein conserved in bacteria - - - - - - - - - - - - - k59_196202_6 31033.ENSTRUP00000010399 1.82e-09 60.1 2BF6Y@1|root,2S16D@2759|Eukaryota,3A216@33154|Opisthokonta,3BQXI@33208|Metazoa,3D8B1@33213|Bilateria,48BMF@7711|Chordata,49B3K@7742|Vertebrata,4A478@7898|Actinopterygii 33208|Metazoa S Leukocyte cell-derived LECT2 GO:0001501,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0006935,GO:0007275,GO:0008150,GO:0009605,GO:0009966,GO:0009968,GO:0010646,GO:0010648,GO:0023051,GO:0023057,GO:0030111,GO:0030178,GO:0032501,GO:0032502,GO:0040011,GO:0042221,GO:0042330,GO:0042802,GO:0044421,GO:0044424,GO:0044464,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0065007 - - - - - - - - - - Peptidase_M23 k59_62803_5 691965.D4P7I8_9CAUD 8.48e-61 193.0 4QGJH@10239|Viruses,4QZ35@35237|dsDNA viruses no RNA stage,4QRZS@28883|Caudovirales,4QMAA@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_310382_1 1219035.NT2_13_00580 1.58e-13 74.7 2FC31@1|root,3446Z@2|Bacteria,1P2BX@1224|Proteobacteria,2UVC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_67405_1 911045.PSE_0025 3.17e-26 108.0 COG3774@1|root,COG3774@2|Bacteria,1R0FT@1224|Proteobacteria,2TYQW@28211|Alphaproteobacteria 28211|Alphaproteobacteria M pathogenesis - - - - - - - - - - - - - k59_67405_2 1499967.BAYZ01000061_gene5937 5.28e-09 62.4 COG4122@1|root,COG4122@2|Bacteria 2|Bacteria E O-methyltransferase activity - - - ko:K05303 - - - - ko00000,ko01000 - - - Methyltransf_24,TylF k59_213747_2 1165094.RINTHH_3920 1.72e-79 250.0 2EVUA@1|root,33P81@2|Bacteria 2|Bacteria - - CP_0543 - - - - - - - - - - - - k59_17491_1 1121929.KB898664_gene1318 3.74e-19 91.7 COG0451@1|root,COG0451@2|Bacteria,1V34Y@1239|Firmicutes,4HCJE@91061|Bacilli,4711M@74385|Gracilibacillus 91061|Bacilli GM NAD(P)H-binding - - - - - - - - - - - - Epimerase,GDP_Man_Dehyd k59_92048_4 145579.C_BPPHM 3.97e-31 111.0 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_92048_6 145579.REP_BPPHM 2.86e-14 72.8 4QFB7@10239|Viruses,4QUN2@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_358527_1 696281.Desru_0862 3.58e-36 135.0 COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,24JGH@186801|Clostridia,2626V@186807|Peptococcaceae 186801|Clostridia S Metal-dependent hydrolase - - - ko:K07043 - - - - ko00000 - - - DUF45 k59_358527_2 211586.SO_0380 1.18e-19 89.7 COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,1RP2Q@1236|Gammaproteobacteria,2QA0Z@267890|Shewanellaceae 1236|Gammaproteobacteria V Subunit R is required for both nuclease and ATPase activities, but not for modification - - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - DUF3387,HSDR_N,ResIII k59_164594_5 742733.HMPREF9469_05060 2.36e-09 62.0 2AUTU@1|root,31KGW@2|Bacteria,1V7KU@1239|Firmicutes,24K4D@186801|Clostridia,222Z3@1506553|Lachnoclostridium 186801|Clostridia - - - - - - - - - - - - - - - k59_55063_3 913970.F8RW84_9VIRU 2.53e-05 53.5 4QCVK@10239|Viruses,4QUMV@29258|ssDNA viruses,4QP4A@10841|Microviridae 10841|Microviridae L ATP binding - - - - - - - - - - - - - k59_382873_10 1333523.L593_06050 1.69e-27 122.0 COG5410@1|root,arCOG09550@2157|Archaea,2XW1V@28890|Euryarchaeota,23Z33@183963|Halobacteria 183963|Halobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - - k59_31079_1 702450.CUW_0526 1.47e-06 52.4 COG4570@1|root,COG4570@2|Bacteria,1VF2H@1239|Firmicutes,3VRYF@526524|Erysipelotrichia 526524|Erysipelotrichia L Endodeoxyribonuclease RusA rusA - - - - - - - - - - - RusA k59_103789_1 1331060.RLDS_05840 4.02e-05 50.8 COG0863@1|root,COG0863@2|Bacteria,1R7KV@1224|Proteobacteria,2U3KV@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K00571,ko:K07319 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase k59_250347_2 1449336.JQLO01000001_gene590 3.9e-19 89.7 COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,4H9TP@91061|Bacilli,27FGK@186828|Carnobacteriaceae 91061|Bacilli M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 k59_201843_1 1788454.A0A190WHE4_9CIRC 1.65e-13 71.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_383543_2 1211814.CAPG01000062_gene2973 0.00035 46.2 COG1595@1|root,COG1595@2|Bacteria,1UZSS@1239|Firmicutes,4HJ8P@91061|Bacilli,1ZH1D@1386|Bacillus 91061|Bacilli K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k59_383683_1 691965.D4P7I3_9CAUD 1.27e-85 286.0 4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae 10699|Siphoviridae S nucleic acid binding - - - - - - - - - - - - - k59_383685_1 1134413.ANNK01000119_gene2442 3.77e-07 54.7 COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HU9A@91061|Bacilli 91061|Bacilli D Phage tail tape measure protein, TP901 family - - - - - - - - - - - - SLT k59_226910_2 411684.HPDFL43_04261 8.86e-22 94.7 COG0741@1|root,COG0741@2|Bacteria,1RH42@1224|Proteobacteria,2UST0@28211|Alphaproteobacteria 28211|Alphaproteobacteria M lytic transglycosylase activity - - - - - - - - - - - - SLT k59_7613_1 428125.CLOLEP_01409 1.12e-290 805.0 COG4626@1|root,COG4626@2|Bacteria,1TT9I@1239|Firmicutes,24AFK@186801|Clostridia,3WNF4@541000|Ruminococcaceae 186801|Clostridia S Phage Terminase - - - - - - - - - - - - Terminase_1 k59_7613_4 691965.D4P7C0_9CAUD 6.43e-31 112.0 4QDUR@10239|Viruses,4QVMY@35237|dsDNA viruses no RNA stage,4QU8R@28883|Caudovirales,4QKNQ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_68614_1 1618236.A0A0C5IB23_9CIRC 3.03e-16 83.6 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_165537_1 76869.PputGB1_1750 8.54e-07 55.5 2AXQF@1|root,31PR8@2|Bacteria,1RKX8@1224|Proteobacteria,1S6JS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_165537_2 318586.Pden_3762 1.82e-87 273.0 28HXV@1|root,2Z83C@2|Bacteria,1PJBP@1224|Proteobacteria,2U8DN@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_226923_1 1449065.JMLL01000011_gene2126 0.000314 44.3 COG1475@1|root,COG1475@2|Bacteria 2|Bacteria K chromosome segregation - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - KorB,ParBc k59_141264_1 436308.Nmar_0146 2.43e-26 110.0 COG1086@1|root,arCOG01375@2157|Archaea,41T0C@651137|Thaumarchaeota 651137|Thaumarchaeota M NAD(P)H-binding - - 4.2.1.115 ko:K15894 ko00520,map00520 - R09697 RC02609 ko00000,ko00001,ko01000 - - - Polysacc_synt_2 k59_238092_1 753085.F4YCV3_9CAUD 2.04e-72 241.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_94673_1 1415780.JPOG01000001_gene1744 2.87e-12 72.4 COG0454@1|root,COG0827@1|root,COG1040@1|root,COG3087@1|root,COG0456@2|Bacteria,COG0827@2|Bacteria,COG1040@2|Bacteria,COG3087@2|Bacteria,1PI1K@1224|Proteobacteria,1T6BU@1236|Gammaproteobacteria,1XB7I@135614|Xanthomonadales 135614|Xanthomonadales D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - - - - - - - - - - - k59_142525_2 387344.LVIS_1385 1.83e-07 52.4 COG1694@1|root,COG1694@2|Bacteria,1VIQA@1239|Firmicutes,4HM6C@91061|Bacilli,3F6WJ@33958|Lactobacillaceae 91061|Bacilli S mazG nucleotide pyrophosphohydrolase - - - - - - - - - - - - MazG k59_301091_2 1219076.N646_0606 9.85e-19 81.6 2CHQ6@1|root,33N6R@2|Bacteria,1NM75@1224|Proteobacteria,1SUNZ@1236|Gammaproteobacteria,1Y1UP@135623|Vibrionales 1236|Gammaproteobacteria S Protein of unknown function (DUF2523) - - - - - - - - - - - - DUF2523 k59_105818_1 1121033.AUCF01000015_gene1508 1.61e-39 139.0 28HS3@1|root,2Z7ZE@2|Bacteria,1QH9A@1224|Proteobacteria,2TVB0@28211|Alphaproteobacteria,2JPPD@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_216263_2 1121370.AQUY01000001_gene998 1.24e-21 92.8 COG4570@1|root,COG4570@2|Bacteria,2GV9V@201174|Actinobacteria,22PE8@1653|Corynebacteriaceae 201174|Actinobacteria L Endodeoxyribonuclease RusA - - - - - - - - - - - - RusA k59_203185_1 1150989.H6WXH4_9CAUD 3.19e-32 117.0 4QB6G@10239|Viruses,4QVYX@35237|dsDNA viruses no RNA stage,4QQS8@28883|Caudovirales 28883|Caudovirales S Peptidase M15 - - - - - - - - - - - - - k59_203185_3 69328.PVLB_09335 2.78e-23 99.0 COG3206@1|root,COG3206@2|Bacteria,1ND5H@1224|Proteobacteria,1RNXC@1236|Gammaproteobacteria 1236|Gammaproteobacteria M DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - - - - - - - - - - - Rad52_Rad22 k59_228065_1 36875.HQ29_09565 5.56e-32 129.0 COG2812@1|root,COG2812@2|Bacteria,4NE8A@976|Bacteroidetes,2FN52@200643|Bacteroidia,22W32@171551|Porphyromonadaceae 976|Bacteroidetes H DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 k59_81790_1 1609634.A0A0C5ANA6_9VIRU 4.31e-13 72.4 4QCA6@10239|Viruses,4QUMI@29258|ssDNA viruses,4QP4E@10841|Microviridae 10841|Microviridae - - - - - - - - - - - - - - - k59_372908_3 1235800.C819_03983 1.05e-07 56.6 28NEI@1|root,2ZBH3@2|Bacteria,1U6F4@1239|Firmicutes,24GVI@186801|Clostridia,27RHM@186928|unclassified Lachnospiraceae 186801|Clostridia - - - - - - - - - - - - - - - k59_166618_1 1234888.K0A2J2_9VIRU 9.03e-52 183.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_179462_1 1157708.KB907450_gene5441 4.38e-08 64.3 COG5434@1|root,COG5434@2|Bacteria,1RCW1@1224|Proteobacteria,2W4G2@28216|Betaproteobacteria 28216|Betaproteobacteria M Pectate lyase superfamily protein - - - - - - - - - - - - Pectate_lyase_3 k59_239435_2 1238182.C882_3082 6.43e-22 91.3 COG1396@1|root,COG1396@2|Bacteria,1RIM2@1224|Proteobacteria,2UAD5@28211|Alphaproteobacteria,2JSA3@204441|Rhodospirillales 204441|Rhodospirillales K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 k59_251776_1 693986.MOC_3358 2.03e-07 57.0 COG1216@1|root,COG1216@2|Bacteria,1PNCS@1224|Proteobacteria,2V0YW@28211|Alphaproteobacteria,1JWHH@119045|Methylobacteriaceae 28211|Alphaproteobacteria S Glycosyl transferase, family 2 - - - - - - - - - - - - Glycos_transf_2 k59_57463_1 314275.MADE_1014600 2.41e-61 199.0 28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF4043) - - - - - - - - - - - - DUF4043 k59_384965_2 270374.MELB17_09838 9.41e-07 54.3 COG0210@1|root,COG0210@2|Bacteria,1R4PV@1224|Proteobacteria,1RZXT@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA helicase - - - - - - - - - - - - AAA_19,DUF87,UvrD-helicase,UvrD_C k59_217415_1 999413.HMPREF1094_02025 6.02e-68 223.0 COG0553@1|root,COG0553@2|Bacteria,1TP2C@1239|Firmicutes 1239|Firmicutes L DEAD-like helicases superfamily - - - - - - - - - - - - Helicase_C,N6_N4_Mtase,SNF2_N k59_118620_3 1197906.CAJQ02000023_gene2189 3.39e-27 110.0 COG0451@1|root,COG0451@2|Bacteria,1RKFJ@1224|Proteobacteria,2UAT9@28211|Alphaproteobacteria 28211|Alphaproteobacteria GM 3-beta hydroxysteroid dehydrogenase/isomerase family - - - - - - - - - - - - Epimerase k59_131824_1 1282360.ABAC460_10200 0.000858 50.1 COG4675@1|root,COG4675@2|Bacteria,1RESM@1224|Proteobacteria,2UQQX@28211|Alphaproteobacteria 28211|Alphaproteobacteria S tail collar domain protein - - - - - - - - - - - - - k59_385940_2 1636182.A0A0F6R7B1_9CAUD 2.89e-69 235.0 4QAWG@10239|Viruses,4QPII@28883|Caudovirales,4QI76@10662|Myoviridae 10662|Myoviridae S DNA helicase activity - - - - - - - - - - - - - k59_385940_4 1524880.A0A076G672_9VIRU 4.02e-119 366.0 4QAXQ@10239|Viruses 10239|Viruses S Ribonucleotide reductase, barrel domain - GO:0001959,GO:0001960,GO:0003674,GO:0003824,GO:0004748,GO:0005575,GO:0008150,GO:0008152,GO:0009966,GO:0009968,GO:0010646,GO:0010648,GO:0010803,GO:0010804,GO:0016491,GO:0016725,GO:0016728,GO:0018995,GO:0023051,GO:0023057,GO:0030430,GO:0033643,GO:0033646,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0055114,GO:0060759,GO:0060761,GO:0061731,GO:0065007 - - - - - - - - - - - k59_302352_1 1692242.A0A0K1RKZ2_9CIRC 8.24e-23 100.0 4QFEW@10239|Viruses,4QUKZ@29258|ssDNA viruses 10239|Viruses - - - - - - - - - - - - - - - k59_217506_2 1347393.HG726020_gene1833 4.84e-60 220.0 28IFC@1|root,2Z8H3@2|Bacteria,4NJUZ@976|Bacteroidetes,2FPHP@200643|Bacteroidia,4ASZB@815|Bacteroidaceae 976|Bacteroidetes - - - - - - - - - - - - - - - k59_20803_1 658401.C7F4C0_9CAUD 1.21e-10 70.9 4QC3V@10239|Viruses,4QVEJ@35237|dsDNA viruses no RNA stage,4QT4B@28883|Caudovirales,4QMPJ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_34687_1 1460635.JCM19038_2660 3.9e-06 49.7 COG0602@1|root,COG0602@2|Bacteria,1TQ58@1239|Firmicutes,4HAJ3@91061|Bacilli 91061|Bacilli H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_12,Fer4_14,Radical_SAM k59_34687_2 1121948.AUAC01000002_gene1213 4.21e-40 138.0 COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,2TSZI@28211|Alphaproteobacteria,43ZGY@69657|Hyphomonadaceae 28211|Alphaproteobacteria H GTP cyclohydrolase I folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI k59_338421_2 1121101.HMPREF1532_04034 4.25e-26 108.0 COG3023@1|root,COG3023@2|Bacteria,4P4CH@976|Bacteroidetes,2FRT5@200643|Bacteroidia,4AQU8@815|Bacteroidaceae 976|Bacteroidetes V N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2 k59_9679_1 401526.TcarDRAFT_1283 7.3e-21 98.6 COG1783@1|root,COG3780@1|root,COG5525@1|root,COG1783@2|Bacteria,COG3780@2|Bacteria,COG5525@2|Bacteria 2|Bacteria S Phage terminase large subunit (GpA) - - - ko:K06909 - - - - ko00000 - - - HTH_3,Terminase_6 k59_229400_1 314275.MADE_1014625 7.7e-41 153.0 COG3780@1|root,COG5362@1|root,COG5410@1|root,COG3780@2|Bacteria,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,1S4YH@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C k59_204372_1 997346.HMPREF9374_1030 2.06e-31 125.0 COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,27BIN@186824|Thermoactinomycetaceae 91061|Bacilli M Mur ligase family, glutamate ligase domain murE - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k59_290930_1 1379715.S5TMW6_9CIRC 1.39e-65 215.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_118769_3 291603.REP7_FBNY1 9.76e-06 51.2 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_217519_1 1123519.PSJM300_14835 1.12e-43 163.0 COG0464@1|root,COG0464@2|Bacteria,1QU82@1224|Proteobacteria,1SA9J@1236|Gammaproteobacteria,1Z2EZ@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria O Zonular occludens toxin (Zot) - - - - - - - - - - - - Zot k59_230433_1 1236959.BAMT01000009_gene3358 0.000149 49.7 COG2520@1|root,COG2520@2|Bacteria,1RIYU@1224|Proteobacteria,2VWI0@28216|Betaproteobacteria 28216|Betaproteobacteria M Methyltransferase FkbM family - - - - - - - - - - - - Methyltransf_21 k59_10492_9 517417.Cpar_0523 1.29e-17 96.7 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1FDI1@1090|Chlorobi 1090|Chlorobi L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 k59_10492_11 1465639.A0A060BKV6_9CAUD 8.32e-14 77.8 4QAM2@10239|Viruses,4QV3W@35237|dsDNA viruses no RNA stage,4QPGK@28883|Caudovirales,4QNW0@10744|Podoviridae 10744|Podoviridae S exonuclease activity - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - - - - - - - - - - - k59_10492_18 706587.Desti_1849 4.26e-53 212.0 COG0726@1|root,COG0726@2|Bacteria,1QZSR@1224|Proteobacteria,43D4Q@68525|delta/epsilon subdivisions 1224|Proteobacteria G PFAM Polysaccharide deacetylase - - - - - - - - - - - - Cadherin_3,Polysacc_deac_1 k59_10492_19 1540095.A0A0A0YP73_9CAUD 1.55e-07 60.8 4QAVB@10239|Viruses,4QPIJ@28883|Caudovirales,4QI48@10662|Myoviridae 10662|Myoviridae S defense response to bacterium - - - - - - - - - - - - - k59_168639_1 883077.HMPREF9241_01708 1.42e-32 128.0 2EDV8@1|root,337QD@2|Bacteria,2GTXK@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - k59_303271_1 105154.Q9MBT9_9VIRU 1.41e-11 62.0 4QCC5@10239|Viruses,4QUKW@29258|ssDNA viruses,4QP4C@10841|Microviridae 10841|Microviridae S viral process - - - - - - - - - - - - - k59_218676_2 1692244.A0A0K1RLR5_9CIRC 8.14e-40 148.0 4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses 10239|Viruses S ATPase activity, uncoupled - GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704 - - - - - - - - - - - k59_241523_5 1234888.K0A2J2_9VIRU 3.29e-116 357.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses 10239|Viruses S Capsid protein (F protein) - - - - - - - - - - - - - k59_278117_3 1217652.F954_02876 6.64e-06 52.8 28MJ5@1|root,2ZAVR@2|Bacteria,1R5CR@1224|Proteobacteria,1SCPR@1236|Gammaproteobacteria,3NMDZ@468|Moraxellaceae 1236|Gammaproteobacteria S Phage stabilisation protein - - - - - - - - - - - - Phage_stabilise k59_144830_1 883078.HMPREF9695_02386 2.56e-52 194.0 COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,2TV6G@28211|Alphaproteobacteria,3JR7Q@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O symbiont process - - - ko:K00612 - - - - ko00000,ko01000 - - - Carbam_trans_C,Carbam_trans_N k59_388355_3 2003327.CAPSD_BPCHP 5.76e-97 313.0 4QFNI@10239|Viruses,4QUMX@29258|ssDNA viruses,4QP49@10841|Microviridae 10841|Microviridae S structural molecule activity - - - - - - - - - - - - - ## 9789 queries scanned ## Total time (seconds): 85.47650933265686 ## Rate: 114.52 q/s